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Difference between revisions of "Vendelin 2018 MiPschool Tromso E1"

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(Created page with "{{Abstract |title=left|90px|Marko Vendelin Restrictions to intracellular diffusion of ATP and ADP in cardiomyocytes. |info=MitoEAGLE |authors=V...")
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{{Abstract
{{Abstract
|title=[[File:Vendelin Marko.jpg|left|90px|Marko Vendelin]] Restrictions to intracellular diffusion of ATP and ADP in cardiomyocytes.
|title=[[File:Vendelin Marko.jpg|left|90px|Marko Vendelin]] Introducing a platform for primary kinetics data analysis.
|info=[[MitoEAGLE]]
|info=[[MitoEAGLE]]
|authors=Vendelin M
|authors=Vendelin M
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|event=MiPschool Tromso-Bergen 2018
|event=MiPschool Tromso-Bergen 2018
|abstract=[[Image:MITOEAGLE-logo.jpg|left|100px|link=http://www.mitoglobal.org/index.php/MITOEAGLE|COST Action MitoEAGLE]]
|abstract=[[Image:MITOEAGLE-logo.jpg|left|100px|link=http://www.mitoglobal.org/index.php/MITOEAGLE|COST Action MitoEAGLE]]
In this talk, I will review the evidence of compartmentalization in the heart muscle cell. On the example of ATP and ADP diffusion, I will show how the system can be studied and which experimental approaches have been applied to analyze the movements of molecules in the cardiac cell. The creatine kinase system and its role in energy transfer between mitochondria, actomyosin and EC coupling system will be discussed.
Typical respiration kinetics study involves many parts with the data analysis playing a large role, as in many other studies. In respiration kinetics data analysis, there are several steps that lead from the measurement data to the desired readout. Here, we present the software package that has been designed for processing kinetics data with the simplicity of the secure access to the data as one of the main focuses of the package. While originally developed for respiration kinetics experiments, we have extended the software to support other experiments, such as patch clamp experiments on cardiomyocytes. The developed software has an extendable plugin system which allows to support multiple hardware providers and experimental protocols.
|editor=[[Beno M]], [[Plangger M]],
|editor=[[Beno M]], [[Plangger M]],
}}
}}

Revision as of 14:23, 2 October 2018

Marko Vendelin
Introducing a platform for primary kinetics data analysis.

Link: MitoEAGLE

Vendelin M (2018)

Event: MiPschool Tromso-Bergen 2018

COST Action MitoEAGLE

Typical respiration kinetics study involves many parts with the data analysis playing a large role, as in many other studies. In respiration kinetics data analysis, there are several steps that lead from the measurement data to the desired readout. Here, we present the software package that has been designed for processing kinetics data with the simplicity of the secure access to the data as one of the main focuses of the package. While originally developed for respiration kinetics experiments, we have extended the software to support other experiments, such as patch clamp experiments on cardiomyocytes. The developed software has an extendable plugin system which allows to support multiple hardware providers and experimental protocols.


β€’ Bioblast editor: Beno M, Plangger M


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Affiliations

Lab Systems Biology, Inst Cybernetics, Tallinn, Estonia