Cell respiration channels metabolic fuels into the chemiosmotic coupling (bioenergetic) machinery of oxidative phosphorylation, being regulated by and regulating oxygen consumption (or consumption of an alternative final electron acceptor) and molecular redox states, ion gradients, mitochondrial (or microbial) membrane potential, the phosphorylation state of the ATP system, and heat dissipation in response to intrinsic and extrinsic energy demands. See also respirometry.
In internal or cell respiration in contrast to fermentation, redox balance is maintained by external electron acceptors, transported into the cell from the environment. The chemical potential between electron donors and electron acceptors drives the electron transfer pathway, generating a chemiosmotic potential that in turn drives ATP synthesis.
Reference: Cell ergometry
Contributed by Gnaiger Erich (2011-11-15) last update 2020-09-10
- For the biochemists respiration refers to the minutiae of breathing at a cellular level, the series of tiny steps in which food is reacted with oxygen to generate an internal voltage with the force of lightning (Lane 2009).
|Gnaiger 2020 BEC MitoPathways||Gnaiger E (2020) Mitochondrial pathways and respiratory control. An introduction to OXPHOS analysis. 5th ed. Bioenerg Commun 2020.2:112 pp. https://doi.org/10.26124/bec:2020-0002||2020|
|BEC 2020.1 doi10.26124bec2020-0001.v1||Gnaiger E et al ― MitoEAGLE Task Group (2020) Mitochondrial physiology. Bioenerg Commun 2020.1. https://doi.org/10.26124/bec:2020-0001.v1||2020|
|Lane 2009 Profile Books, London||Lane N (2009) Life ascending. The ten great inventions of evolution. Profile Books, London 344 pp.||2009|
MitoPedia methods: Respirometry