Chandel 2021 Cold Spring Harb Perspect Biol
From Bioblast
Revision as of 16:54, 1 March 2023 by Gnaiger Erich (talk | contribs)
Chandel NS (2021) Mitochondria. Cold Spring Harb Perspect Biol 13:a040543. doi: 10.1101/cshperspect.a040543 |
Chandel NS (2021) Cold Spring Harb Perspect Biol
Abstract:
β’ Bioblast editor: Gnaiger E
Correction: FADH2 and S-pathway
- A commonly found error on FADH2 in the S-pathway requires correction. For clarification, see page 48 in Gnaiger (2020)
- Quote (p 48): "The substrate of CII is succinate, which is oxidized forming fumarate while reducing flavin adenine dinucleotide FAD to FADH2, with further electron transfer to the quinone pool. Whereas reduced NADH is a substrate of Complex I linked to dehydrogenases of the TCA cycle and mt-matrix upstream of CI, reduced FADH2 is a product of Complex II with downstream electron flow from CII to Q."
- A commonly found error on FADH2 in the S-pathway requires correction. For clarification, see page 48 in Gnaiger (2020)
- Gnaiger E (2020) Mitochondrial pathways and respiratory control. An introduction to OXPHOS analysis. 5th ed. Bioenerg Commun 2020.2. https://doi.org/10.26124/bec:2020-0002