Jones 2017 Elsevier
From Bioblast
Jones PM, Bennett MJ (2017) Chapter 4 - Disorders of mitochondrial fatty acid Ξ²-oxidation. Elsevier In: Garg U, Smith LD , eds. Biomarkers in inborn errors of metabolism. Clinical aspects and laboratory determination:87-101. https://doi.org/10.1016/C2014-0-03841-5 |
Jones PM, Bennett MJ (2017) Elsevier
Abstract:
β’ Bioblast editor: Gnaiger E
Correction: FADH2 and S-pathway
- A commonly found error on FADH2 in the S-pathway requires correction. For clarification, see page 48 in Gnaiger (2020)
- Quote (p 48): "The substrate of CII is succinate, which is oxidized forming fumarate while reducing flavin adenine dinucleotide FAD to FADH2, with further electron transfer to the quinone pool. Whereas reduced NADH is a substrate of Complex I linked to dehydrogenases of the TCA cycle and mt-matrix upstream of CI, reduced FADH2 is a product of Complex II with downstream electron flow from CII to Q."
- A commonly found error on FADH2 in the S-pathway requires correction. For clarification, see page 48 in Gnaiger (2020)
- Gnaiger E (2020) Mitochondrial pathways and respiratory control. An introduction to OXPHOS analysis. 5th ed. Bioenerg Commun 2020.2. https://doi.org/10.26124/bec:2020-0002
Labels:
Pathway: F, S