Klocker Helmut

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COST Action CA15203 (2016-2021): MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping

Klocker Helmut

MitoPedia topics: EAGLE 

COST: Member COST WG1: WG1

Name	Klocker Helmut, Prof., MD
Institution
Address	Department of Urology, Medical University of Innsbruck,
City	Innsbruck
State/Province
Country	Austria
Email
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O2k-Network Lab

Labels: Field of research: Clinical 

Publications

	Published	Reference
Bastos Sant'Anna Silva 2021 Cancers (Basel)	2021	Bastos Sant'Anna Silva AC, Perez Valencia JA, Sciacovelli M, Lalou C, Sarlak S, Tronci L, Nikitopoulou E, Meszaros AT, Frezza C, Rossignol R, Gnaiger E, Klocker H (2021) Succinate anaplerosis has an onco-driving potential in prostate cancer cells. https://doi.org/10.3390/cancers13071727
Schoepf 2020 Nat Commun	2020	Schöpf B, Weissensteiner H, Schäfer G, Fazzini F, Charoentong P, Naschberger A, Rupp B, Fendt L, Bukur V, Giese I, Sorn P, Sant’Anna-Silva AC, Iglesias-Gonzalez J, Sahin U, Kronenberg F, Gnaiger E, Klocker H (2020) OXPHOS remodeling in high-grade prostate cancer involves mtDNA mutations and increased succinate oxidation. Nat Commun 11:1487. https://doi.org/10.1038/s41467-020-15237-5
BEC 2020.1 doi10.26124bec2020-0001.v1	2020	Gnaiger E et al ― MitoEAGLE Task Group (2020) Mitochondrial physiology. Bioenerg Commun 2020.1. https://doi.org/10.26124/bec:2020-0001.v1
Weber 2018 Int J Mol Sci	2018	Weber A, Klocker H, Oberacher H, Gnaiger E, Neuwirt H, Sampson N, Eder IE (2018) Succinate accumulation is associated with a shift of mitochondrial respiratory control and HIF-1α upregulation in PTEN negative prostate cancer cells. Int J Mol Sci 19:2129.
Schoepf 2016 FEBS J	2016	Schöpf B, Schäfer G, Weber A, Talasz H, Eder IE, Klocker H, Gnaiger E (2016) Oxidative phosphorylation and mitochondrial function differ between human prostate tissue and cultured cells. https://doi.org/10.1111/febs.13733
Dueregger 2015 PLoS One	2015	Dueregger A, Schöpf B, Eder T, Höfer J, Gnaiger E, Aufinger A, Kenner L, Perktold B, Ramoner R, Klocker H, Eder IE (2015) Differential utilization of dietary fatty acids in benign and malignant cells of the prostate. PLoS One 10(8):e0135704.
Ofer 2015 Mol Endocrinol	2015	Ofer P, Heidegger I, Eder IE, Schöpf B, Neuwirt H, Geley S, Klocker H, Massoner P (2015) Both IGF1R and INSR knockdown exert anti-tumorigenic effects in prostate cancer in vitro and in vivo. Mol Endocrinol 29:1694-707.

Abstracts

	Published	Reference
Bastos Sant'Anna Silva 2019 Life Sciences Meeting 2019 Innsbruck AT	2019	Cellular succinate transport and mitochondrial respiratory function in prostate cancer.
Schoepf 2018 33rd Annual EAU Congress Copenhagen	2018	Shift of mitochondrial oxidative phosphorylation is associated with mtDNA mutational load in primary prostate cancer tissue.
Bastos Sant'Anna Silva 2018 TRANSMIT Bertinoro di Romagna IT	2018	Cellular succinate transport and mitochondrial respiratory function in prostate cancer.
Bastos Sant'Anna Silva 2018 MiPschool Tromso C4	2018	Role of succinate in prostate cancer cells: uptake and mitochondrial respiratory function.
Gnaiger 2017 Abstract EUROMIT2017 Cologne	2017	Again not a Warburg effect - mitochondrial function in primary prostate cancer.
Gnaiger 2016 Abstract UMDF2016	2016	Schöpf B, Schäfer G, Weber A, Talasz H, Eder IE, Klocker H, Gnaiger E (2016) Oxidative phosphorylation and mitochondrial function differ between human prostate tissue and cultured cells.
Schoepf 2016 Abstract Androgens 2016	2016	Mitochondrial function and mitochondrial heteroplasmy levels differ between benign and malignant prostate tissue.
Weber 2016 Abstract Mito Xmas Meeting Innsbruck	2016	Loss of PTEN in prostate cancer cells leads to a switch to succinate-mediated mitochondrial respiration associated with increased expression of NaDC3 and HIF-1alpha.
Schoepf 2016 Abstract Mito Xmas Meeting Innsbruck	2016	Mitochondrial function in primary prostate cancer.
Schoepf 2014 Abstract MiP2014	2014	OXPHOS analysis in small prostate biopsies.