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From Bioblast
Year | Reference | Coupling | Pathway | Preparation | Organism | Tissue;cell | |
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Larsen 2020 Acta Physiol (Oxf) | 2020 | Larsen FJ, Schiffer TA, Zinner C, Willis SJ, Morales-Alamo D, Calbet J, Boushel R, Holmberg HC (2020) Mitochondrial oxygen affinity increases after sprint interval training and is related to the improvement in peak oxygen uptake. https://doi.org/10.1111/apha.13463 | OXPHOS | N NS | Isolated mitochondria | Human | Skeletal muscle |
Bhaskaran 2020 Aging Cell | 2020 | Bhaskaran S, Pollock N, C Macpherson P, Ahn B, Piekarz KM, Staunton CA, Brown JL, Qaisar R, Vasilaki A, Richardson A, McArdle A, Jackson MJ, Brooks SV, Van Remmen H (2020) Neuron-specific deletion of CuZnSOD leads to an advanced sarcopenic phenotype in older mice. Aging Cell 19:e13225. | LEAK OXPHOS | N S CIV NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
De-Souza 2020 J Biol Chem | 2020 | De-Souza EA, Pimentel FSA, De-Queiroz ALFV, Camara H, Felix-Formiga ML, Machado CM, Pinto S, Galina A, Mori MA, Montero-Lomelí M, Masuda CA (2020) The yeast protein Ubx4p contributes to mitochondrial respiration and lithium-galactose-mediated activation of the unfolded protein response. J Biol Chem 295:3773-82. | LEAK OXPHOS | N Gp NS ROX | Isolated mitochondria Intact cells | Caenorhabditis elegans Saccharomyces cerevisiae | |
Rebane-Klemm 2020 Cancers (Basel) | 2020 | Rebane-Klemm E, Truu L, Reinsalu L, Puurand M, Shevchuk I, Chekulayev V, Timohhina N, Tepp K, Bogovskaja J, Afanasjev V, Suurmaa K, Valvere V, Kaambre T (2020) Mitochondrial respiration in KRAS and BRAF mutated colorectal tumors and polyps. Cancers (Basel) 12:E815. | LEAK OXPHOS | N NS | Permeabilized tissue | Human | Endothelial;epithelial;mesothelial cell |
Falcao-Tebas 2020 J Physiol | 2020 | Falcão-Tebas F, Marin EC, Kuang J, Bishop DJ, McConell GK (2020) Maternal exercise attenuates the lower skeletal muscle glucose uptake and insulin secretion caused by paternal obesity in female adult rat offspring. J Physiol 598:4251-70. | LEAK OXPHOS ET | N NS ROX | Permeabilized tissue | Rat | Skeletal muscle |
Chandramouleeswaran 2020 PLoS One | 2020 | Chandramouleeswaran PM, Guha M, Shimonosono M, Whelan KA, Maekawa H, Sachdeva UM, Ruthel G, Mukherjee S, Engel N, Gonzalez MV, Garifallou J, Ohashi S, Klein-Szanto AJ, Mesaros CA, Blair IA, Pellegrino da Silva R, Hakonarson H, Noguchi E, Baur JA, Nakagawa H (2020) Autophagy mitigates ethanol-induced mitochondrial dysfunction and oxidative stress in esophageal keratinocytes. PLoS One 15:e0239625. | ROUTINE OXPHOS | N S CIV ROX | Permeabilized cells Intact cells | Mouse | Endothelial;epithelial;mesothelial cell |
Grewal 2020 Exp Neurol | 2020 | Grewal R, Reutzel M, Dilberger B, Hein H, Zotzel J, Marx S, Tretzel J, Sarafeddinov A, Fuchs C, Eckert GP (2020) Purified oleocanthal and ligstroside protect against mitochondrial dysfunction in models of early Alzheimer's disease and brain ageing. Exp Neurol 328:113248. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Intact cells | Human | Neuroblastoma |
Carvalho 2020 BMC Nutr | 2020 | Carvalho E, Adams SH, Borsheim E, Blackburn ML, Ono-Moore KD, Cotter M, Bowlin AK, Yeruva L (2020) Neonatal diet impacts liver mitochondrial bioenergetics in piglets fed formula or human milk. BMC Nutr 6:13. | LEAK OXPHOS | N NS ROX | Permeabilized tissue | Pig | Liver |
Edmunds 2020 Mol Metab | 2020 | Edmunds LR, Xie B, Mills AM, Huckestein BR, Undamatla R, Murali A, Pangburn MM, Martin J, Sipula I, Kaufman BA, Scott I, Jurczak MJ (2020) Liver-specific Prkn knockout mice are more susceptible to diet-induced hepatic steatosis and insulin resistance. Mol Metab 41:101051. | LEAK OXPHOS ET | F N ROX | Homogenate | Mouse | Liver |
Risiglione 2020 Int J Mol Sci | 2020 | Risiglione P, Leggio L, Cubisino SAM, Reina S, Paternò G, Marchetti B, Magrì A, Iraci N, Messina A (2020) High-resolution respirometry reveals MPP+ mitochondrial toxicity mechanism in a cellular model of parkinson's disease. Int J Mol Sci 21:E7809. https://doi.org/10.3390/ijms21217809 | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | Neuroblastoma |
Belosludtsev 2020 Biochimie | 2020 | Belosludtsev KN, Belosludtseva NV, Kosareva EA, Talanov EY, Gudkov SV, Dubinin MV (2020) Itaconic acid impairs the mitochondrial function by the inhibition of complexes II and IV and induction of the permeability transition pore opening in rat liver mitochondria. Biochimie 176:150-57. | LEAK OXPHOS | N S CIV | Isolated mitochondria | Rat | Liver |
Wen 2020 Biomedicines | 2020 | Wen JJ, Cummins CB, Williams TP, Radhakrishnan RS (2020) The genetic evidence of burn-induced cardiac mitochondrial metabolism dysfunction . Biomedicines 8:E566. | LEAK OXPHOS ET | N S NS | Permeabilized tissue | Rat | Heart |
Zhang 2020 Chemosphere | 2020 | Zhang Y, Li Y, Feng Q, Shao M, Yuan F, Liu F (2020) Polydatin attenuates cadmium-induced oxidative stress via stimulating SOD activity and regulating mitochondrial function in Musca domestica larvae. Chemosphere 248:126009. | LEAK OXPHOS | N S ROX | Isolated mitochondria | Hexapods | |
Alexopoulos 2020 Nat Commun | 2020 | Alexopoulos SJ, Chen SY, Brandon AE, Salamoun JM, Byrne FL, Garcia CJ, Beretta M, Olzomer EM, Shah DP, Philp AM, Hargett SR, Lawrence RT, Lee B, Sligar J, Carrive P, Tucker SP, Philp A, Lackner C, Turner N, Cooney GJ, Santos WL, Hoehn KL (2020) Mitochondrial uncoupler BAM15 reverses diet-induced obesity and insulin resistance in mice. Nat Commun 11:2397. | LEAK | N | Permeabilized tissue Homogenate | Mouse | Skeletal muscle Liver Fat |
Magnesa 2020 Thesis | 2020 | Magnesa B (2020) Skeletal muscle mitochondrial oxidative phosphorylation plasticity in two studies on humans: exercise training effect in obese subjects and bed rest effect in healthy subjects. PhD Thesis 81. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Nascimento-Dos-Santos 2020 Biochim Biophys Acta Mol Basis Dis | 2020 | Nascimento-Dos-Santos G, de-Souza-Ferreira E, Lani R, de Faria CC, Araujo VG, Teixeira-Pinheiro LC, de Souza Vasconcelos T, Leandro TG, Santiago MF, Linden R, Galina A, Petrs-Silva H (2020) Neuroprotection from optic nerve injury and modulation of oxidative metabolism by transplantation of active mitochondria to the retina. Biochim Biophys Acta Mol Basis Dis 1866:165686. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Isolated mitochondria Intact cells | Rat | Liver Nervous system |
Vaccari 2020 Eur J Appl Physiol | 2020 | Vaccari F, Passaro A, D'Amuri A, Sanz JM, Di Vece F, Capatti E, Magnesa B, Comelli M, Mavelli I, Grassi B, Fiori F, Bravo G, Avancini A, Parpinel M, Lazzer S (2020) Effects of 3-month high-intensity interval training vs. moderate endurance training and 4-month follow-up on fat metabolism, cardiorespiratory function and mitochondrial respiration in obese adults. Eur J Appl Physiol 120:1787-803. | LEAK OXPHOS ET | N S NS | Permeabilized tissue | Human | Skeletal muscle |
Rodrigues 2020 J Appl Physiol (1985) | 2020 | Rodrigues GC, Rocha NN, Maia LA, Melo I, Simões AC, Antunes MA, Bloise FF, Woyames J, da-Silva WS, Capelozzi VL, Abela G, Ball L, Pelosi P, Rocco PRM, Silva PL (2020) Impact of experimental obesity on diaphragm structure, function and bioenergetics. J Appl Physiol (1985) 129:1062-74. | LEAK OXPHOS ET | N CIV NS | Permeabilized tissue | Rat | Skeletal muscle |
Ehrlicher 2020 FASEB J | 2020 | Ehrlicher SE, Stierwalt HD, Miller BF, Newsom SA, Robinson MM (2020) Mitochondrial adaptations to exercise do not require Bcl2-mediated autophagy but occur with BNIP3/Parkin activation. FASEB J 34:4602-18. | LEAK OXPHOS ET | F N S NS | Isolated mitochondria | Mouse | Skeletal muscle |
Song 2020 Life Sci | 2020 | Song K, Zhang Y, Ga Q, Bai Z, Ge RL (2020) High-altitude chronic hypoxia ameliorates obesity-induced non-alcoholic fatty liver disease in mice by regulating mitochondrial and AMPK signaling. Life Sci 252:117633. | LEAK OXPHOS ET | F N NS | Homogenate | Mouse | Liver |
Pereira 2020 PLoS One | 2020 | Pereira GC, Lee L, Rawlings N, Ouwendijk J, Parker JE, Andrienko TN, Henley JM, Halestrap AP (2020) Hexokinase II dissociation alone cannot account for changes in heart mitochondrial function, morphology and sensitivity to permeability transition pore opening following ischemia. PLoS One 15:e0234653. | LEAK OXPHOS | N | Isolated mitochondria | Rat | Heart |
Hroudova 2020 Mol Neurobiol | 2020 | Hroudová J, Nováková T, Korábečný J, Maliňák D, Górecki L, Fišar Z (2020) Effects of novel tacrine derivatives on mitochondrial energy metabolism and monoamine oxidase activity-in vitro study. Mol Neurobiol 58:1102-13. | OXPHOS | N S ROX | Isolated mitochondria | Pig | Nervous system |
Szibor 2020 J Biol Chem | 2020 | Szibor Marten, Gizatullina Zemfira, Gainutdinov Timur, Endres Thomas, Debska-Vielhaber Grazyna, Kunz Matthias, Karavasili Niki, Hallmann Kerstin, Schreiber Frank, Bamberger Alexandra, Schwarzer Michael, Doenst Torsten, Heinze Hans-Jochen, Leßmann Volkmar, Vielhaber Stefan, Kunz Wolfram S, Gellerich Frank Norbert (2020) Cytosolic, but not matrix, calcium is essential for adjustment of mitochondrial pyruvate supply. J Biol Chem 295:4383-97. | LEAK OXPHOS | N S Gp CIV NS ROX | Isolated mitochondria Intact cells | Mouse | Nervous system |
Feng 2020 Int J Biol Macromol | 2020 | Feng Q, Shao M, Han J, Tang T, Zhang Y, Liu F (2020) TFAM, a potential oxidative stress biomarker used for monitoring environment pollutants in Musca domestica. Int J Biol Macromol 155:524-34. | LEAK OXPHOS | N S ROX | Isolated mitochondria | Hexapods | |
Skemiene 2020 J Bioenerg Biomembr | 2020 | Skemiene K, Pampuscenko K, Rekuviene E, Borutaite V (2020) Protective effects of anthocyanins against brain ischemic damage. J Bioenerg Biomembr 52:71-82. | LEAK OXPHOS | N | Isolated mitochondria | Rat | Nervous system |
Buch 2020 FASEB J | 2020 | Buch BT, Halling JF, Ringholm S, Gudiksen A, Kjøbsted R, Olsen MA, Wojtaszewski JFP, Pilegaard H (2020) Colchicine treatment impairs skeletal muscle mitochondrial function and insulin sensitivity in an age-specific manner. FASEB J 34:8653-70. | LEAK OXPHOS | N NS | Permeabilized tissue | Mouse | Skeletal muscle |
Visavadiya 2020 Mol Cell Biochem | 2020 | Visavadiya NP, Pena GS, Khamoui AV (2020) Mitochondrial dynamics and quality control are altered in a hepatic cell culture model of cancer cachexia. Mol Cell Biochem 476:23-34. | LEAK OXPHOS ET | N S NS ROX | Permeabilized cells | Mouse | Liver |
Purhonen 2020 Nat Commun | 2020 | Purhonen J, Grigorjev V, Ekiert R, Aho N, Rajendran J, Pietras R, Truvé K, Wikström M, Sharma V, Osyczka A, Fellman V, Kallijärvi J (2020) A spontaneous mitonuclear epistasis converging on Rieske Fe-S protein exacerbates complex III deficiency in mice. Nat Commun 11:322. | LEAK OXPHOS ET | N NS ROX | Isolated mitochondria | Mouse | Liver Kidney |
Bloise 2020 Thyroid | 2020 | Bloise FF, Santos AT, Brito JT, Andrade CBV, Oliveira TS, Souza AF, Fontes KN, Silva JD, Blanco NG, Silva PL, Rocco PRM, Fliers E, Boelen A, da-Silva WS, Ortiga-Carvalho TM (2020) Sepsis impairs thyroid hormone signaling and mitochondrial function in the mouse diaphragm. Thyroid 30:1079-90. | LEAK OXPHOS ET | N CIV NS | Permeabilized tissue | Mouse | Skeletal muscle |
Barsottini 2020 Commun Biol | 2020 | Barsottini MRO, Copsey A, Young L, Baroni RM, Cordeiro AT, Pereira GAG, Moore AL (2020) Biochemical characterization and inhibition of the alternative oxidase enzyme from the fungal phytopathogen Moniliophthora perniciosa. Commun Biol 3:263. | OXPHOS | F N S CIV | Protists | ||
Musi 2020 Aging Cell | 2020 | Musi N, Valentine JM, Sickora KR, Baeuerle E, Thompson CS, Shen Q, Orr ME (2020) Tau protein aggregation is associated with cellular senescence in the brain. Aging Cell 17:e12840. | LEAK OXPHOS ET | N S NS ROX | Homogenate | Mouse | Nervous system |
Hardee 2020 Mol Metab | 2020 | Hardee JP, Martins KJB, Miotto PM, Ryall JG, Gehrig SM, Reljic B, Naim T, Chung JD, Trieu J, Swiderski K, Philp AM, Philp A, Watt MJ, Stroud DA, Koopman R, Steinberg GR, Lynch GS (2020) Metabolic remodeling of dystrophic skeletal muscle reveals biological roles for dystrophin and utrophin in adaptation and plasticity. Mol Metab 45:101157. | OXPHOS LEAK | N NS | Permeabilized tissue | Mouse | Skeletal muscle |
Pena 2020 Int J Chronic Dis | 2020 | Pena GS, Paez HG, Johnson TK, Halle JL, Carzoli JP, Visavadiya NP, Zourdos MC, Whitehurst MA, Khamoui AV (2020) Hippocampal growth factor and myokine cathepsin B expression following aerobic and resistance training in 3xTg-AD mice. Int J Chronic Dis 2020:Article ID 5919501. | LEAK OXPHOS ET | N S NS ROX | Homogenate | Mouse | Nervous system |
Eshima 2020 J Appl Physiol (1985) | 2020 | Eshima H, Siripoksup P, Mahmassani ZS, Johnson JM, Ferrara PJ, Verkerke ARP, Salcedo A, Drummond MJ, Funai K (2020) Neutralizing mitochondrial ROS does not rescue muscle atrophy induced by hindlimb unloading in female mice. J Appl Physiol (1985) 129:124-32. | LEAK OXPHOS ET | N NS | Isolated mitochondria | Mouse | Skeletal muscle |
Bose 2020 Aging Cell | 2020 | Bose C, Alves I, Singh P, Palade PT, Carvalho E, Børsheim E, Jun SR, Cheema A, Boerma M, Awasthi S, Singh SP (2020) Sulforaphane prevents age-associated cardiac and muscular dysfunction through Nrf2 signaling. Aging Cell 19:e13261. | LEAK OXPHOS | F N CIV NS ROX | Permeabilized tissue | Mouse | Heart |
Hafstad 2020 Antioxidants (Basel) | 2020 | Hafstad AD, Hansen SS, Lund J, Santos CXC, Boardman NT, Shah AM, Aasum E (2020) NADPH oxidase 2 mediates myocardial oxygen wasting in obesity. Antioxidants (Basel) 9:E171. | LEAK OXPHOS | F N | Isolated mitochondria | Mouse | Heart |
Burtscher 2020 Int J Mol Sci | 2020 | Burtscher J, Di Pardo A, Maglione V, Schwarzer C, Squitieri F (2020) Mitochondrial respiration changes in R6/2 Huntington's Disease model mice during aging in a brain region specific manner. Int J Mol Sci 21:5412. | LEAK OXPHOS ET | N S CIV NS ROX | Homogenate | Mouse | Nervous system |
Matsuo 2020 Am J Physiol Endocrinol Metab | 2020 | Matsuo FS, Araújo PHC, Mota RF, Carvalho AJR, Queiroz MS, Almeida BB, Ferreira KCOS, Metzner RJM, Ferrari GD, Alberici LC, Osako MK (2020) RANKL induces beige adipocyte differentiation in preadipocytes. Am J Physiol Endocrinol Metab 318:E866-77. | LEAK OXPHOS | N | Permeabilized cells | Mouse | Fat |
Weber 2020 FASEB J | 2020 | Weber M, Mera P, Casas J, Salvador J, Rodríguez A, Alonso S, Sebastián D, Soler-Vázquez MC, Montironi C, Recalde S, Fucho R, Calderón-Domínguez M, Mir JF, Bartrons R, Escola-Gil JC, Sánchez-Infantes D, Zorzano A, Llorente-Cortes V, Casals N, Valentí V, Frühbeck G, Herrero L, Serra D (2020) Liver CPT1A gene therapy reduces diet-induced hepatic steatosis in mice and highlights potential lipid biomarkers for human NAFLD. FASEB J 34:11816-37. | LEAK OXPHOS | N NS | Isolated mitochondria | Mouse | Liver |
Contreras Mostazo 2020 Cancers (Basel) | 2020 | Mostazo MGC, Kurrle N, Casado M, Fuhrmann D, Alshamleh I, Häupl B, Martín-Sanz P, Brüne B, Serve H, Schwalbe H, Schnütgen F, Marin S, Cascante M (2020) Metabolic plasticity is an essential requirement of acquired tyrosine kinase inhibitor resistance in chronic myeloid leukemia. Cancers (Basel) 12:E3443. | LEAK ROUTINE OXPHOS ET | F N S Gp CIV ROX | Permeabilized cells Intact cells | Human | Blood cells |
Groennebaek 2020 Cells | 2020 | Groennebaek T, Billeskov TB, Schytz CT, Jespersen NR, Bøtker HE, Olsen RKJ, Eldrup N, Nielsen J, Farup J, De Paoli FV, Vissing K (2020) Mitochondrial structure and function in the metabolic myopathy accompanying patients with critical limb ischemia. Cells 9:E570. | LEAK OXPHOS | N NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Reutzel 2020 Oxid Med Cell Longev | 2020 | Reutzel M, Grewal R, Dilberger B, Silaidos C, Joppe A, Eckert GP (2020) Cerebral mitochondrial function and cognitive performance during aging: A longitudinal study in NMRI mice. Oxid Med Cell Longev 2020:4060769. | LEAK ET OXPHOS | N S CIV ROX | Isolated mitochondria | Mouse | Nervous system |
Larsen 2020 Cardiovasc Drugs Ther | 2020 | Larsen AH, Wiggers H, Dollerup OL, Jespersen NR, Hansson NH, Frøkiær J, Brøsen K, Nørrelund H, Bøtker HE, Møller N, Jessen N (2020) Metformin lowers body weight but fails to increase insulin sensitivity in chronic heart failure patients without diabetes: a randomized, double-blind, placebo-controlled study. Cardiovasc Drugs Ther 35:491-503. | LEAK OXPHOS ET | N NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Oellermann 2020 Sci Rep | 2020 | Oellermann M, Hickey AJR, Fitzgibbon QP, Smith G (2020) Thermal sensitivity links to cellular cardiac decline in three spiny lobsters. Sci Rep 10:202. | LEAK OXPHOS ET | N S NS | Homogenate | Crustaceans | Heart |
Khamoui 2020 Physiol Genomics | 2020 | Khamoui AV, Tokmina-Roszyk D, Rossiter HB, Fields GB, Visavadiya NP (2020) Hepatic proteome analysis reveals altered mitochondrial metabolism and suppressed acyl-CoA synthetase-1 in colon-26 tumor-induced cachexia. Physiol Genomics 52:203-16. | LEAK OXPHOS ET | N NS | Intact cells | Mouse | Liver |
Brunetta 2020 J Physiol | 2020 | Brunetta HS, Politis-Barber V, Petrick HL, Dennis KMJH, Kirsh AJ, Barbeau PA, Nunes EA, Holloway GP (2020) Nitrate attenuates HFD-induced glucose intolerance in association with reduced epididymal adipose tissue inflammation and mitochondrial ROS emission. J Physiol 598:3357-71. | LEAK OXPHOS | N NS | Permeabilized tissue | Mouse | Fat |
Bundgaard 2020 J Exp Biol | 2020 | Bundgaard A, Qvortrup K, Rasmussen LJ, Fago A (2020) Turtles maintain mitochondrial integrity but reduce mitochondrial respiratory capacity in the heart after cold acclimation and anoxia. J Exp Biol 222:jeb200410. | LEAK OXPHOS ET | N NS | Permeabilized tissue | Amphibians | Heart |
Duong 2020 Mitochondrion | 2020 | Duong QV, Hoffman A, Zhong K, Dessinger MJ, Zhang Y, Bazil JN (2020) Calcium overload decreases net free radical emission in cardiac mitochondria. Mitochondrion 51:126-39. | LEAK OXPHOS ET | F N S | Isolated mitochondria | Guinea pig | Heart |
Kanellopoulos 2020 Cell | 2020 | Kanellopoulos AK, Mariano V, Spinazzi M, Woo YJ, McLean C, Pech U, Li KW, Armstrong JD, Giangrande A, Callaerts P, Smit AB, Abrahams BS, Fiala A, Achsel T, Bagni C (2020) Aralar sequesters GABA into hyperactive mitochondria, causing social behavior deficits. Cell 180:1178-97. | LEAK OXPHOS ET | N S CIV NS ROX | Homogenate | Drosophila | Nervous system Other cell lines |
Dulac 2020 J Physiol | 2020 | Dulac M, Leduc-Gaudet JP, Reynaud O, Ayoub MB, Guérin A, Finkelchtein M, Hussain SN, Gouspillou G (2020) Drp1 knockdown induces severe muscle atrophy and remodelling, mitochondrial dysfunction, autophagy impairment and denervation . J Physiol 598:3691-710. | LEAK OXPHOS | N NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |