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Difference between revisions of "Template:Current week ecosystem agenda"

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  2020 Week 43
{{Template:Science for Ukraine}}
  2024 Week 17


* '''Oct-19 Mo'''  
* '''Apr-22 Mo'''
:{|
:{|
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]
|'''Did you know that safranin can exert an inhibitory effect on mitochondrial respiration?'''<br>
|'''How can I evaluate the effect of one specific titration of a complex SUIT protocol?'''<br>
Application of safranin leads to partial inhibition of NADH-linked respiration and above 2 µM on the succinate-linked respiration. By running a control high-resolution respirometry experiment without the fluorophore, you can detect and do quality control for this inhibitory effect.<br>
Flux control efficiencies express the change in respiration after a single step, in which there is a change in a metabolic control variable.<br>
- You can read more about it in the following publication: »[[Krumschnabel 2014 Methods Enzymol]]« <br>
- »'''[[Flux control efficiency]]'''«, »'''[[Metabolic control variable]]'''«<br>
- communicated by »[[Komlodi Timea]]« and »[[Cecatto Cristiane]]«
- communicated by »[[Cardoso Luiza]]« and »[[Baglivo Eleonora]]«  
|}
|}
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* '''Oct-20 Tu''' - [[12th_%C3%96GMBT_Annual_Meeting_2020_Virtual_Event#Programme|ÖGMBT Life Science Tuesdays]]
* '''Apr-23 Tu'''  
 
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* '''Apr-24 We'''
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* '''Oct-21 We'''
* '''Apr-25 Th'''
:{|
:{|
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]
|'''Blood cell respirometry might be an attractive alternative to skeletal- and cardiac muscle-based assessment of mitochondrial function in human studies '''<br>
|'''"Our results further enhance the understanding and relevance of bioenergetic function in liver ischemia and transplantation and provide the basis for further consideration of these parameters as biomarkers in LT [liver transplantation]."''' <br>
:from the O2k-Network »[[US NC Winston-Salem Molina AJA]]«
* Meszaros AT, Weissenbacher A, Schartner M, Egelseer-Bruendl T, Hermann M, Unterweger J, Mittelberger C, Reyer BA, Hofmann J, Zelger BG, Hautz T, Resch T, Margreiter C, Maglione M, Komlódi T, Ulmer H, Cardini B, Troppmair J, Öfner D, Gnaiger E, Schneeberger S, Oberhuber R (2024) The predictive value of graft viability and bioenergetics testing towards the outcome in liver transplantation. [[Meszaros_2024_Transpl_Int|»Bioblast link«]]
*Tyrrell DJ, Bharadwaj MS, Jorgensen MJ, Register TC, Molina AJ (2016) Blood cell respirometry is associated with skeletal and cardiac muscle bioenergetics: Implications for a minimally invasive biomarker of mitochondrial health. Redox Biol 10:65-77.[[Tyrrell 2016 Redox Biol|»Bioblast link«]]
:from the O2k-Network »[[AT Innsbruck Schneeberger S]] and [[AT Innsbruck Oroboros]]«
|}
|}  
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* '''Apr-26 Fr'''
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'''<big>Next Week</big>'''
2024 Week 18
 
* '''Apr-29 Mo'''
:{|
:{|
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]
|''' Human [[PBMC]] and [[Platelet]] - minimally invasive samples for HRR '''<br>
|'''How can I update DatLab 8 to the latest version?'''<br>
Read about isolation procedures for these sample types.<br>
If your computer with DatLab 8 is connected to the internet, go to “Check for updates” in the Help menu of DatLab 8, and follow the simple installation instructions. <br>
- »'''[[MiPNet21.17_BloodCellsIsolation|MiPNet21.17 Blood Cells Isolation]]'''« <br>
- »'''[[Updating - DatLab]]'''«, »'''[https://www.oroboros.at/index.php/product/datlab/ DatLab 8]'''«<br>
- communicated by »[[Cecatto Cristiane]]« and »[[Garcia-Souza Luiz F]]«  
- communicated by »[[Leo Elettra]]« and »[[Baglivo Eleonora]]«
|}
|}
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* '''Oct-22 Th'''
* '''Apr-30 Tu'''
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* '''May-01 We'''   
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* '''May-02 Th'''  
:{|
:{|
 
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]
| width="110" align="center" | [[File:BEC-logo.png|left|100px|link=Bioenergetics Communications|Bioenergetics Communications]]
|''' "In respirometric studies on blood cells, the purity of cell preparation should always be emphasized and documented." '''<br>
|''' LEAK respiration relates to intrinsic uncoupling.   '''<br>
- »'''[[MiPNet21.17 BloodCellsIsolation]]'''«<br>
Non-phosphorylating LEAK respiration is measured in the absence of externally added uncouplers (i) in the absence of adenylates, (ii) after depletion of ADP, or (iii) after inhibition of ATP synthase or adenine nucleotide translocase.  <br>
- communicated by »[[Timon-Gomez Alba]]« and »[[Baglivo Eleonora]]«
- »'''[https://www.bioenergetics-communications.org/index.php/BEC_2020.1_doi10.26124bec2020-0001.v1 BEC2020.1: Mitochondrial physiology]'''« - Table 2. Terms on respiratory coupling and uncoupling  <br>
- communicated by »[[Komlodi Timea]]« and »[[Cecatto Cristiane]]« and »[[Gnaiger Erich]]«
|}
|}
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* '''Oct-23 Fr'''  
* '''May-03 Fr'''
:{|
| width="100" align="center" | [[File:O2k-brief.png|45px|link=http://wiki.oroboros.at/index.php/O2k-brief|O2k-brief repository]]
|'''Simultaneous measurement of O<sub>2</sub> flux and mt-membrane potential: A method to detect deficiency in mitochondrial electron transfer system''' <br>
: from the O2k-Network »[[AT Innsbruck Oroboros]]« and »[[AT Innsbruck Gnaiger E]]«<br>
* Krumschnabel G, Eigentler A, Fasching M, Gnaiger E (2014) Use of safranin for the assessment of mitochondrial membrane potential by high-resolution respirometry and fluorometry. Methods Enzymol 542:163-81.  [[Krumschnabel 2014 Methods Enzymol|»Bioblast link«]]
|}

Latest revision as of 08:23, 22 April 2024

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A future for Ukraine is the future of its science
2024 Week 17
  • Apr-22 Mo
MitoPedia
How can I evaluate the effect of one specific titration of a complex SUIT protocol?

Flux control efficiencies express the change in respiration after a single step, in which there is a change in a metabolic control variable.
- »Flux control efficiency«, »Metabolic control variable«
- communicated by »Cardoso Luiza« and »Baglivo Eleonora« 


  • Apr-23 Tu

  • Apr-24 We

  • Apr-25 Th
O2k-Publications in the MiPMap "Our results further enhance the understanding and relevance of bioenergetic function in liver ischemia and transplantation and provide the basis for further consideration of these parameters as biomarkers in LT [liver transplantation]."
  • Meszaros AT, Weissenbacher A, Schartner M, Egelseer-Bruendl T, Hermann M, Unterweger J, Mittelberger C, Reyer BA, Hofmann J, Zelger BG, Hautz T, Resch T, Margreiter C, Maglione M, Komlódi T, Ulmer H, Cardini B, Troppmair J, Öfner D, Gnaiger E, Schneeberger S, Oberhuber R (2024) The predictive value of graft viability and bioenergetics testing towards the outcome in liver transplantation. »Bioblast link«
from the O2k-Network »AT Innsbruck Schneeberger S and AT Innsbruck Oroboros«

  • Apr-26 Fr

Next Week

2024 Week 18
  • Apr-29 Mo
O2k-Open SupportInfo: improve How can I update DatLab 8 to the latest version?

If your computer with DatLab 8 is connected to the internet, go to “Check for updates” in the Help menu of DatLab 8, and follow the simple installation instructions.
- »Updating - DatLab«, »DatLab 8«
- communicated by »Leo Elettra« and »Baglivo Eleonora«


  • Apr-30 Tu

  • May-01 We

  • May-02 Th
O2k-Open SupportInfo: improve "In respirometric studies on blood cells, the purity of cell preparation should always be emphasized and documented."

- »MiPNet21.17 BloodCellsIsolation«
- communicated by »Timon-Gomez Alba« and »Baglivo Eleonora«


  • May-03 Fr