Difference between revisions of "Uncoupler"
From Bioblast
| Line 6: | Line 6: | ||
*[[Non-coupled respiration]] | *[[Non-coupled respiration]] | ||
*[[Uncoupler titration]] | *[[Uncoupler titration]] | ||
*[[Optimum uncoupler concentration]] | |||
|type=Chemicals | |type=Chemicals | ||
}} | }} | ||
| Line 12: | Line 13: | ||
|type=Chemicals | |type=Chemicals | ||
}} | }} | ||
http://www.bmb.leeds.ac.uk/illingworth/oxphos/poisons.htm | http://www.bmb.leeds.ac.uk/illingworth/oxphos/poisons.htm | ||
Revision as of 11:02, 9 August 2011
- high-resolution terminology - matching measurements at high-resolution
Uncoupler
Description
An uncoupler is a protonophore (FCCP, CCCP, DNP) which cycles across the inner mt-membrane with transport of protons and dissipation of the electrochemical proton gradient. Mild uncoupling may be induced at low uncoupler concentrations, the non-coupled state of ETS capacity is obtained at optimum uncoupler concentration for maximum flux, whereas at higher concentrations an uncoupler-induced inhibition is observed.
See also:
Abbreviation: u
MitoPedia topics:
Uncoupler
... more about "Uncoupler"
An uncoupler is a protonophore (FCCP … An uncoupler is a protonophore (FCCP, CCCP, DNP) which cycles across the inner mt-membrane with transport of protons and dissipation of the electrochemical proton gradient. Mild uncoupling may be induced at low uncoupler concentrations, the non-coupled state of ETS capacity is obtained at optimum uncoupler concentration for maximum flux, whereas at higher concentrations an uncoupler-induced inhibition is observed. </br></br>See also: </br>*Non-coupled respiration</br>*Uncoupler titration</br>*Optimum uncoupler concentrationOptimum uncoupler concentration +
Respirometry +
Uncoupler +
