Kane Daniel A

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COST Action CA15203 (2016-2021): MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping

Kane Daniel A

MitoPedia topics: EAGLE

COST: Member

COST WG2: WG2

Name	Kane Daniel A, Assistant Prof., PhD ORCID ID
Institution	Department of Human Kinetics, St. Francis Xavier University, CA
Address	1 West Street Nova Scotia B2G 2W5,
City	Antigonish
State/Province
Country	Canada
Email	dkane@stfx.ca
Weblink
O2k-Network Lab	CA Antigonish Kane DA, US NC Greenville Neufer PD

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Publications

	Published	Reference
BEC 2020.1 doi10.26124bec2020-0001.v1	2020	Gnaiger E et al ― MitoEAGLE Task Group (2020) Mitochondrial physiology. Bioenerg Commun 2020.1. https://doi.org/10.26124/bec:2020-0001.v1
D'Souza 2018 J Lipid Res	2018	D'Souza K, Nzirorera C, Cowie AM, Varghese GP, Trivedi P, Eichmann TO, Biswas D, Touaibia M, Morris AJ, Aidinis V, Kane DA, Pulinilkunnil T, Kienesberger PC (2018) Autotaxin-LPA signaling contributes to obesity-induced insulin resistance in muscle and impairs mitochondrial metabolism. J Lipid Res 59:1805-17.
Herbst 2017 Appl Physiol Nutr Metab	2017	Herbst EAF, George MAJ, Brebner K, Holloway GP, Kane DA (2017) Lactate is oxidized outside of the mitochondrial matrix in rodent brain. Appl Physiol Nutr Metab 43:467-74.
Hughes 2015 Front Physiol	2015	Hughes MC, Ramos SV, Turnbull PC, Nejatbakhsh A, Baechler BL, Tahmasebi H, Laham R, Gurd BJ, Quadrilatero J, Kane DA, Perry CG (2015) Mitochondrial bioenergetics and fiber type assessments in microbiopsy vs. Bergstrom percutaneous sampling of human skeletal muscle. Front Physiol 6:360.
Elustondo 2014 Biochim Biophys Acta	2014	Elustondo PA, Negoda A, Kane CL, Kane DA, Pavlov EV (2014) Spermine selectively inhibits high-conductance, but not low-conductance calcium-induced permeability transition pore. Biochim Biophys Acta 1847:231–40.
Perry 2013 Diabetes	2013	Perry CG, Kane DA, Lanza IR, Neufer PD (2013) Methods for assessing mitochondrial function in diabetes. Diabetes 62:1041-53. https://doi.org/10.2337/db12-1219
Elustondo 2013 J Biol Chem	2013	Elustondo PA, White AE, Hughes ME, Brebner K, Pavlov E, Kane DA (2013) Physical and functional association of lactate dehydrogenase (LDH) with skeletal muscle mitochondria. J Biol Chem 288:25309-17.
Smith 2013 Biochem J	2013	Smith ME, Tippetts TS, Brassfield ES, Tucker BJ, Ockey A, Swensen AC, Anthonymuthu TS, Washburn TD, Kane DA, Prince JT, Bikman BT (2013) Mitochondrial fission mediates ceramide-induced metabolic disruption in skeletal muscle. Biochem J 456:427-39.
Kwak 2012 Free Radic Biol Med	2012	Kwak HB, Thalacker-Mercer A, Anderson EJ, Lin CT, Kane DA, Lee NS, Cortright RN, Bamman MM, Neufer PD (2012) Simvastatin impairs ADP-stimulated respiration and increases mitochondrial oxidative stress in primary human skeletal myotubes. Free Radic Biol Med 52:198-207.
Perry 2012 J Physiol	2012	Perry CG, Kane DA, Herbst EA, Mukai K, Lark DS, Wright DC, Heigenhauser GJ, Neufer PD, Spriet LL, Holloway GP (2012) Mitochondrial creatine kinase activity and phosphate shuttling are acutely regulated by exercise in human skeletal muscle. J Physiol 590: 5475-5486.
Kane 2011 Am J Physiol Endocrinol Metab	2011	Kane DA, Lin CT, Anderson EJ, Kwak HB, Cox JH, Brophy PM, Hickner RC, Neufer PD, Cortright RN (2011) Progesterone increases skeletal muscle mitochondrial H₂O₂ emission in non-menopausal women. Am J Physiol Endocrinol Metab 300:E528-35.
Perry 2011 Biochem J	2011	Perry CG, Kane DA, Lin CT, Kozy R, Cathey BL, Lark DS, Kane CL, Brophy PM, Gavin TP, Anderson EJ, Neufer PD (2011) Inhibiting myosin-ATPase reveals a dynamic range of mitochondrial respiratory control in skeletal muscle. Biochem J 437:215-22.
Kane 2010 Free Radic Biol Med	2010	Kane DA, Anderson EJ, Price III JW, Woodlief TL, Lin C-T, Bikman BT, Cortright RN, Neufer PD (2010) Metformin selectively attenuates mitochondrial H₂O₂ emission without affecting respiratory capacity in skeletal muscle of obese rats. Free Radic Biol Med 49:1082–7.
Anderson 2009 J Clin Invest	2009	Anderson EJ, Lustig ME, Boyle KE, Woodlief TL, Kane DA, Lin C-T, Price JW, Kang L, Rabinovitch PS, Szeto HH, Houmard JA, Cortright RN, Wasserman DH, Neufer PD (2009) Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans. J Clin Invest 119:573-81.

Abstracts

	Published	Reference
Wallace 2018 FASEB J	2018	Effects of H₁/H₂ histamine receptor blockade on mitochondrial function in rodent brain following prolonged exercise.
Kane 2016 Abstract MitoFit Science Camp 2016	2016	Effects of inhibiting myosin-ATPase on mitochondrial respiratory capacity in permeabilized skeletal muscle.
George 2015 Abstract MiPschool Greenville 2015	2015	Mitochondria do not directly oxidize lactate within the cerebral cortex or hippocampus.
Kane 2015 Fatty Acid Oxidation O2k-Network Discussion Forum	2015	Kane 2015 Fatty Acid Oxidation O2k-Network Discussion Forum
Perry 2014 Abstract MiP2014	2014	Evaluation of critical experimental parameters for assessing mitochondrial bioenergetics in permeabilized myofibers.
Kane 2014 Abstract MiP2014	2014	Assessing mitochondrial lactate oxidation in permeabilized skeletal muscle fibers highlights important experimental considerations: malate concentration and the cytochrome c effect.

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