SUIT-003 Ce1;ce2SD;ce3U;ce4Rot;ce5Ama: Difference between revisions
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::: '''[[Categories of SUIT protocols |SUIT-category]]:''' RE(S) | ::: '''[[Categories of SUIT protocols |SUIT-category]]:''' RE(S) | ||
::: '''[[SUIT protocol pattern]]:''' complex [[coupling control protocol]] ( | ::: '''[[SUIT protocol pattern]]:''' complex [[coupling control protocol]] (ceCCP) | ||
'''R;L;E | '''R;L;E format_1ce;2ceS;3ceU-''' | ||
[[File:R;L;E format_1R;2S;3U-.jpg|left|200px]] | [[File:R;L;E format_1R;2S;3U-.jpg|left|200px]] | ||
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== | == Cell coupling control protocol == | ||
{| class="wikitable" border="1" | {| class="wikitable" border="1" | ||
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|- | |- | ||
| | | 1ce | ||
| [[ROUTINE]] | | [[ROUTINE]] | ||
| [[Intact cells |ce]] | | [[Intact cells |ce]] | ||
| Intact cells, ce, are in the ROUTINE state of respiration. | | Intact cells, ce, are in the ROUTINE state of respiration. Mitochondria of dead cells (dce) without substrate are in a state of ROX. | ||
|- | |- | ||
| | | 2ceS | ||
| ''R''+S<sub>''L''</sub> | | ''R''+S<sub>''L''</sub> | ||
| [[ROUTINE]] (''R'') + [[S]] (S<sub>''L''</sub>) | | [[ROUTINE]] (''R'') + [[S]] (S<sub>''L''</sub>) | ||
| | | dce are in state S<sub>''L''</sub>. ADP should be added to stimulate mitochondria in dce to the OXPHOS state; see [[CCP(S)02]]. | ||
|- | |- | ||
| | | 3ceU | ||
| ''E''+S<sub>''E''</sub> | | ''E''+S<sub>''E''</sub> | ||
| [[ETS]] (''E'') + [[S]] (S<sub>''E''</sub>) | | [[ETS]] (''E'') + [[S]] (S<sub>''E''</sub>) | ||
| ce and | | ce and dce are in the ETS state. | ||
|- | |- | ||
| | | 4ceRot | ||
| ROX+S<sub>''E''</sub> | | ROX+S<sub>''E''</sub> | ||
| [[ROX]]+[[S]] (S<sub>''E''</sub>) | | [[ROX]]+[[S]] (S<sub>''E''</sub>) | ||
| ce are in the ROX state, | | ce are in the ROX state, dce are in the ETS state. | ||
|- | |- | ||
| | | 5ceAma | ||
| ROX<sub>Ama</sub> | | ROX<sub>Ama</sub> | ||
| [[ROX]] | | [[ROX]] | ||
Revision as of 00:17, 5 August 2017
- high-resolution terminology - matching measurements at high-resolution
SUIT-003 Ce1;ce2SD;ce3U;ce4Rot;ce5Ama
Description
Abbreviation: RE(S)
Reference: B Steinlechner-Maran 1997 Transplantation
MitoPedia concepts:
SUIT protocol,
SUIT B
- SUIT-category: RE(S)
- SUIT protocol pattern: complex coupling control protocol (ceCCP)
R;L;E format_1ce;2ceS;3ceU-
Cell coupling control protocol
| Step | Respiratory state | Pathway control | Comment |
|---|---|---|---|
| 1ce | ROUTINE | ce | Intact cells, ce, are in the ROUTINE state of respiration. Mitochondria of dead cells (dce) without substrate are in a state of ROX. |
| 2ceS | R+SL | ROUTINE (R) + S (SL) | dce are in state SL. ADP should be added to stimulate mitochondria in dce to the OXPHOS state; see CCP(S)02. |
| 3ceU | E+SE | ETS (E) + S (SE) | ce and dce are in the ETS state. |
| 4ceRot | ROX+SE | ROX+S (SE) | ce are in the ROX state, dce are in the ETS state. |
| 5ceAma | ROXAma | ROX |
