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Body mass excess

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Body mass excess

Description

The body mass excess, BME, is a lifestyle metric. The BME with respect to the healthy reference population, HRP, is defined as BME ≝ M/M°. Thus the BME expresses your actual body mass, M [kg], relative to the reference body mass, M° [kg], for your height, H [m], in the HRP. A balanced BME is BME° = 1.0 with a band width of -0.1 towards underweight and +0.2 towards overweight. Considering a height of 1.78 m, the balanced body mass is M° = 65.9 kg, and overweight is reached at a weight gain of 20 % or BME = 1.2 (1.2M° = 79 kg; body mass index BMI1.2 = 24.9 kg·m-2). At a height of 1.84 m, the balanced body mass is M° = 72.4 kg, and obesity is reached at a weight gain of 40 % or BME = 1.4 (1.4M° = 101.4 kg; BMI1.4 = 29.9 kg·m-2).

Abbreviation: BME

Reference: Gnaiger 2019 MiP2019

BME - the body mass excess calculator

» BME calculator
Erich Gnaiger and Paolo Cocco - last update 2019-12-14
Figure 1: Four phases of the allometric relationship between body mass, M°, and height, H, in the healthy reference population (HRP), and shift of M at body mass excess, BME, indicating underweight (BME = 0.8 and 0.9) or overweight (BME = 1.2) and increasing degrees of obesity (1.4 to 2.0). Compared to the HRP, the body mass index, BMI, assumes a more shallow increase of M° with H, hence a BMI of 20 indicates overweight (1.2M°) at 1.38 m, but underweight (0.9M°) at 1.92 m.
Figure 2: Body mass index, BMI, as a function of height in the four phases of the allometric relationship, at reference body mass, M°, of the healthy reference population (HRP), and at body mass excess, BME, from 0.8 to 2.0. Norwegian HUNT 3 study: women and men from the 20-29 to the 60-69 age group; N=1735 and 1815, respectively. Germany - Kiel Obesity Prevention Study: girls and boys in four age groups of 9.2 to 10.4 years; N=6280 and 6171, respectively. The worldwide trend towards an increase in body mass is apparent in comparison to the reference BMI° of the adult HRP, but trends of BMI of children and adolescents are not correlated with those of adults (NCD Risk Factor Collaboration 2017 Lancet).
The BME calculator is based on the WHO database on children up to 10 years of age (WHO Multicentre Growth Reference Study Group, WHO MGRS 2006), and on the Committee on Biological Handbooks data set (CBH; Zimmer 1962) on adoselscents to adults (Fig. 1), according to the tables listed below. The results have to be critically evaluated. The BME calculator applies to healthy controls (except for obesity), without sarcopenia.
  1. Open the BME calculator by clicking here (press Ctrl and left mouse click): BME calculator
  2. Click into the field Height, H [m], and enter your height in meters [m] (not cm), using the dot (not the comma) as a separator for decimal places. Example: 1.70
  3. Click into the field Body mass, M [kg], and enter your mass (weight) in kilograms [kg] (not pounds), using the dot (not the comma) as a separator for decimal places. Example: 63.4
  4. Click into the field Click here for results. This activates the caclulator. Results are displayed in the fields below.
    1. The body mass excess, BME, is calculated from your height and body mass. Example: 1.1 (With a BME of 1.1 you are 10 % above the reference body mass, which is well within the normal range.) The percentage is calculated as (BME-1)*100.
    2. For comparison with a commonly used index, the Body mass index, BMI [kg·m-2], is calculated from your body mass divided by your height squared. Example: 21.9 (What does this index tell you?)
    3. The Reference body mass, M°, is calculated from your height and shows the corresponding body mass of a person from the healthy reference population. Example: 57.7 (Compare your measured body mass of 63.4 kg with the reference body mass of 57.7 kg.)
    4. The expected maximum aerobic exercise capacity per body mass, VO2max/m, at a BME of 1.1 is 55 mL·min-1·kg-1. The calculated VO2max/m applies to healthy adults, and does not apply to BME<1.
    5. The Overweight body mass, 1.2M°, and Obese body mass, 1.4M°, are calculated from the reference body mass. You can compare these cut-off values with your actual body mass. Example: 69.2 (More than 69.2 kg is rated as overweight for a height of 1.70 m with BME=1.2.); 80.8 (More than 80.8 kg is rated as obese for a height of 1.70 m with BME=1.4.)
  5. If you want to edit the height or body mass entered above, click into the corresponding field, delete the previously entered number, enter the new number, and click into the field Click here for results.
The body mass is measured on a calibrated balance in light underware without shoes.


Body mass excess (BME) compared to body mass index (BMI)

  • Balanced standard: BME = 1.0
  • Overweight: BME > 1.2
  • Obese: BME > 1.4
  • For 0.45 to 1.26 m heights (newborns and children), the tables are based on data for WHO Child Growth Standards (WHO Multicentre Growth Reference Study Group, WHO MGRS [8, 9]) compiled from Brazil, Ghana, India, Norway, Oman and the USA, reporting as little as 3 % differences between these groups studied in affluent neighborhoods and raised in environments that do not constrain growth [8]. At the same height the body mass of girls and boys differs less than ±2 % from the common fitted curve, except for a difference of +3 % for boys at 0.70 to 0.77 m and -3 % for girls at 0.62 to 0.64 m.
  • For heights of 1.27 m and above, the tables are based on the Committee on Biological Handbooks data set (CBH [2]), compiled from publications between 1931 to 1944 [3-7]. These agree with WHO MGRS data at heights 1.27 to 1.4 m (children and adolescents) [9] within 1 %, and agree on noting no difference in the curves for females and males, but adult females do not reach the same heights as males. Body mass and heights are not different in girls and boys at the corresponding age of 8 to 10 years.


BME at height 0.45 - 0.62 m

Based on WHO MGRS [9]: M° = 28.60·H3.086
BME 0.45-0.62.png

BME at height 0.63 - 1.02 m

Based on WHO MGRS [9]: M° = 15.08·H1.704
BME 0.63-1.02.png

BME at height 1.03 - 1.26 m

Based on WHO MGRS [9]: M° = 14.89·H2.178
BME 1.03-1.26.png

BME at height 1.27 - 2.0 m

Based on Biological Handbooks [9], extrapolated >1.8 m: M° = 12.68·H2.857
BME 1.27-1.6.png
BME 1.6-1.8.png
BME 1.8-2.0.png


References and links

  1. Gnaiger E (2019) OXPHOS capacity in human muscle tissue and body mass excess – the MitoEAGLE mission towards an integrative database. 14th Conference on Mitochondrial Physiology: Mitochondrial function: changes during life cycle and in noncommunicable diseases - COST MitoEAGLE perspectives and MitoEAGLE WG and MC Meeting. Belgrade RS, 13-16 Oct 2019. - »Bioblast link«
  2. Zucker TF (1962) Regression of standing and sitting weights on body weight: man. In: Altman PL, Dittmer DS, eds: Growth including reproduction and morphological development. Committee on Biological Handbooks, Fed Amer Soc Exp Biol:336-7. – Anthropometry, h and m°, of the healthy reference population, HRP; based on [3-7].
  3. Bayley N, Davis FC (1935) Growth changes in bodily size and proportions during the first three years. Biometrika 27:26-87.
  4. Gray H, Ayres JG (1931) Growth in private school children. Behavior Res Fund Monog, Univ Chicago Press, Chicago:282 pp. – With averages and variabilities based on 3110 measurings on boys and 1473 on girls from the ages of one to nineteen years.
  5. Meredith HV (1935) Univ Iowa studies in child welfare 11(3).
  6. Peatman JG, Higgons RA (1938) Growth norms from birth to the age of five years: a study of children reared with optimal pediatric and home care. Am J Diseases Children 55:1233-1247.
  7. Simmons KW (1944) Monographs Soc Research in Child Develop 9(1).
  8. WHO Multicentre Growth Reference Study Group (2006) WHO child growth standards based on length/height, weight and age. Acta PĂŠdiatrica Suppl 450:76-85.
  9. WHO Multicentre Growth Reference Study Group (2006) WHO child growth standards: length/height-for-age, weight-for-age, weight-for-length, weight-for-height and body mass index-for-age: Methods and development. Geneva: World Health Organization:312 pp.
Links
  1. BME calculator
  2. https://ourworldindata.org/obesity
  3. https://ourworldindata.org/human-height
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Publications BME

Sort in ascending/descending order by a click on one of the small symbols in squares below.
Default sorting: chronological. Empty fields appear first in ascending order. 
 YearReferenceOrganismTissue;cellStressDiseases
National Academies of Sciences, Engineering, and Medicine 2023 BMI and beyond2023National Academies of Sciences, Engineering, and Medicine (2023) BMI and beyond: Considering context in measuring obesity and its applications: Proceedings of a workshop—in brief. The National Academies Press, Washington, DC https://doi.org/10.17226/27185HumanFatObesity
Gnaiger 2020 MitoFit x2021Gnaiger E (2021) The elementary unit — canonical reviewer's comments on: Bureau International des Poids et Mesures (2019) The International System of Units (SI) 9th ed. https://doi.org/10.26124/mitofit:200004.v2Human
Chambers 2020 J Appl Physiol (1985)2020Chambers TL, Burnett TR, Raue U, Lee GA, Finch WH, Graham BM, Trappe TA, Trappe S (2020) Skeletal muscle size, function, and adiposity with lifelong aerobic exercise. J Appl Physiol (1985) 128:368–78.HumanSkeletal muscle
Fat
Aging;senescence
Misra 2019 J Postgrad Med2019Misra P, Singh AK, Archana S, Lohiya A, Kant S (2019) Relationship between body mass index and percentage of body fat, estimated by bio-electrical impedance among adult females in a rural community of North India: A cross-sectional study. J Postgrad Med 65:134-40.HumanFatObesity
Hood 2019 Nutr Diabetes2019Hood K, Ashcraft J, Watts K, Hong S, Choi W, Heymsfield SB, Gautam RK, Thomas D (2019) Allometric scaling of weight to height and resulting body mass index thresholds in two Asian populations. Nutr Diabetes 9:2. doi: 10.1038/s41387-018-0068-3.HumanObesity
Mialich 2018 J Electr Bioimp2018Mialich MS, Silva BR, Jordao AA (2018) Cutoff points of BMI for classification of nutritional status using bioelectrical impedance analysis. J Electr Bioimp 9:24-30.HumanFatObesity
Wollner 2017 J Public Health Res2017Wollner M, Paulo Roberto BB, Alysson Roncally SC, Jurandir N, Edil LS (2017) Accuracy of the WHO's body mass index cut-off points to measure gender- and age-specific obesity in middle-aged adults living in the city of Rio de Janeiro, Brazil. J Public Health Res 6:904.HumanFatObesity
NCD-RisC 2017 Lancet2017NCD Risk Factor Collaboration (NCD-RisC) (2017) Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and adults. Lancet 390:2627–42.HumanObesity
Korre 2016 Am J Cardiol2016Korre M, Porto LG, Farioli A, Yang J, Christiani DC, Christophi CA, Lombardi DA, Kovacs RJ, Mastouri R, Abbasi S, Steigner M, Moffatt S, Smith D, Kales SN (2016) Effect of body mass index on left ventricular mass in career male firefighters. Am J Cardiol 118:1769-1773.HumanHeartCardiovascular
Obesity
Distefano 2016 J Gerontol A Biol Sci Med Sci2016Distefano G, Standley RA, Dubé JJ, Carnero EA, Ritov VB, Stefanovic-Racic M, Toledo FG, Piva SR, Goodpaster BH, Coen PM (2016) Chronological age does not influence ex-vivo mitochondrial respiration and quality control in skeletal muscle. J Gerontol A Biol Sci Med Sci 72:535-42.HumanSkeletal muscleAging;senescence
Indian Academy of Pediatrics Growth Charts Committee 2015 Indian Pediatr2015Indian Academy of Pediatrics Growth Charts Committee, Khadilkar V, Yadav S, Agrawal KK, Tamboli S, Banerjee M, Cherian A, Goyal JP, Khadilkar A, Kumaravel V, Mohan V, Narayanappa D, Ray I, Yewale V (2015) Revised IAP growth charts for height, weight and body mass index for 5- to 18-year-old Indian children. Indian Pediatr 52:47-55.HumanAging;senescence
Obesity
Gnaiger 2015 Scand J Med Sci Sports2015Gnaiger E, Boushel R, SĂžndergaard H, Munch-Andersen T, Damsgaard R, Hagen C, DĂ­ez-SĂĄnchez C, Ara I, Wright-Paradis C, Schrauwen P, Hesselink M, Calbet JAL, Christiansen M, Helge JW, Saltin B (2015) Mitochondrial coupling and capacity of oxidative phosphorylation in skeletal muscle of Inuit and caucasians in the arctic winter. https://doi.org/10.1111/sms.12612HumanSkeletal muscleTemperature
Mialich 2014 Nutr Hosp2014Mialich MS, Martinez EZ, Jordao JJ (2014) Application of body mass index adjusted for fat mass (BMIfat) obtained by bioelectrical impedance in adults. Nutr Hosp 30:417-24.HumanFatObesity
Loe 2013 PLOS ONE2013Loe H, Rognmo Ø, Saltin B, WislÞff U (2013) Aerobic capacity reference data in 3816 healthy men and women 20-90 years. PLOS ONE 8:e64319.Human
Andersen 2013 Int J Circumpolar Health2013Andersen S, Fleischer Rex K, Noahsen P, SĂžrensen HC, Mulvad G, Laurberg P (2013) Raised BMI cut-off for overweight in Greenland Inuit--a review. Int J Circumpolar Health 2013 Aug 5;72. doi: 10.3402/ijch.v72i0.21086.Obesity
Pesta 2011 Am J Physiol Regul Integr Comp Physiol2011Pesta D, Hoppel F, Macek C, Messner H, Faulhaber M, Kobel C, Parson W, Burtscher M, Schocke M, Gnaiger E (2011) Similar qualitative and quantitative changes of mitochondrial respiration following strength and endurance training in normoxia and hypoxia in sedentary humans. Am J Physiol Regul Integr Comp Physiol 301:R1078–87.HumanSkeletal muscleHypoxiaObesity
Meeuwsen 2010 Clin Nutr2010Meeuwsen S, Horgan GW, Elia M (2010) The relationship between BMI and percent body fat, measured by bioelectrical impedance, in a large adult sample is curvilinear and influenced by age and sex. Clin Nutr 29:560-6.HumanFatAging;senescence
Obesity
Pribis 2010 Nutrients2010Pribis P, Burtnack CA, McKenzie SO, Thayer J (2010) Trends in body fat, body mass index and physical fitness among male and female college students. Nutrients 2:1075-85.HumanObesity
Bosy-Westphal 2009 Br J Nutr2009Bosy-Westphal A, Plachta-Danielzik S, Dörhöfer RP, MĂŒller MJ (2009) Short stature and obesity: positive association in adults but inverse association in children and adolescents. Br J Nutr 102:453-61.FatObesity
Gnaiger 2009 Int J Biochem Cell Biol2009Gnaiger E (2009) Capacity of oxidative phosphorylation in human skeletal muscle. New perspectives of mitochondrial physiology. https://doi.org/10.1016/j.biocel.2009.03.013Human
Mouse
Skeletal muscleAging;senescence
Obesity
Raboel 2009 Diabetes Obes Metab2009Raboel R, Hojberg PM, Almdal T, Boushel RC, Haugaard SB, Madsbad S, Dela F (2009) Improved glycaemic control decreases inner mitochondrial membrane leak in type 2 diabetes. Diabetes Obes Metab 11:355-60.HumanSkeletal muscleMitochondrial diseaseDiabetes
Daussin 2008 Am J Physiol Regul Integr Comp Physiol2008Daussin FN, Zoll J, Dufour SP, Ponsot E, Lonsdorfer-Wolf E, Doutreleau S, Mettauer B, Piquard F, Geny B, Richard R (2008) Effect of interval versus continuous training on cardiorespiratory and mitochondrial functions: relationship to aerobic performance improvements in sedentary subjects. Am J Physiol Regul Integr Comp Physiol 295:R264-72.HumanSkeletal muscle
Romero-Corral 2008 Int J Obes (Lond)2008Romero-Corral A, Somers VK, Sierra-Johnson J, Thomas RJ, Collazo-Clavell ML, Korinek J, Allison TG, Batsis JA, Sert-Kuniyoshi FH, Lopez-Jimenez F (2008) Accuracy of body mass index in diagnosing obesity in the adult general population. Int J Obes (Lond) 32:959-66.HumanFatObesity
De Onis 2007 Bull World Health Organization2007de Onis M, Onyango AW, Borghi E, Siyam A, Nishida C, Siekmann J (2007) Development of a WHO growth reference for school-aged children and adolescents. Bull World Health Organization 85:660-7.HumanObesity
Boushel 2007 Diabetologia2007Boushel RC, Gnaiger E, Schjerling P, Skovbro M, Kraunsoee R, Dela F (2007) Patients with Type 2 diabetes have normal mitochondrial function in skeletal muscle. Diabetologia 50:790-6.HumanSkeletal muscleDiabetes
Obesity
Bakkman 2007 ActaPhysiol2007Bakkman L, Sahlin K, Holmberg HC, Tonkonogi M (2007) Quantitative and qualitative adaptation of human skeletal muscle mitochondria to hypoxic compared with normoxic training at the same relative work rate. Acta Physiol (Oxford) 190:243–51.HumanSkeletal muscleOxidative stress;RONS
Mogensen 2006 J Physiol2006Mogensen M, Bagger M, Pedersen PK, Fernström M, Sahlin K (2006) Cycling efficiency in humans is related to low UCP3 content and to type I fibres but not to mitochondrial efficiency. J Physiol 571:669-81.HumanSkeletal muscle
Ponsot 2006 J Appl Physiol (1985)2006Ponsot E, Dufour SP, Zoll J, Doutrelau S, N'Guessan B, Geny B, Hoppeler H, Lampert E, Mettauer B, Ventura-Clapier R, Richard R (2006) Exercise training in normobaric hypoxia in endurance runners. II. Improvement of mitochondrial properties in skeletal muscle. J Appl Physiol (1985) 100:1249-57.HumanSkeletal muscleHypoxia
Garnier 2005 FASEB J2005Garnier A, Fortin D, Zoll J, N'Guessan B, Mettauer B, Lampert E, Veksler V, Ventura-Clapier R (2005) Coordinated changes in mitochondrial function and biogenesis in healthy and diseased human skeletal muscle. FASEB J 19:43-52.HumanSkeletal muscle
N'Guessan 2004 Mol Cell Biochem2004N'Guessan B, Zoll J, Ribera F, Ponsot E, Lampert E, Ventura-Clapier R, Veksler V, Mettauer B (2004) Evaluation of quantitative and qualitative aspects of mitochondrial function in human skeletal and cardiac muscles. Mol Cell Biochem 256-257:267-80.HumanSkeletal muscle
Rasmussen 2003 Eur J Physiol2003Rasmussen UF, Krustrup P, Kjaer M, Rasmussen HN (2003) Human skeletal muscle mitochondrial metabolism in youth and senescence: no signs of functional changes in ATP formation and mitochondrial oxidative capacity. Pflugers Arch – Eur J Physiol 446:270-78.HumanSkeletal muscleAging;senescence
Zoll 2002 J Physiol2002Zoll J, Sanchez H, N'Guessan B, Ribera F, Lampert E, Bigard X, Surrurier B, Fortin D, Geny B, Veksler V, Ventura-Clapier R, Mettauer B (2002) Physical activity changes the regulation of mitochondrial respiration in human skeletal muscle. J Physiol 543:191-200.HumanSkeletal muscle
Deurenberg 2001 Eur J Clin Nutr2001Deurenberg P, Andreoli A, Borg P, Kukkonen-Harjula K, de Lorenzo A, van Marken Lichtenbelt WD, Testolin G, Vigano R, Vollaard N (2001) The validity of predicted body fat percentage from body mass index and from impedance in samples of five European populations. Eur J Clin Nutr 55:973-9.HumanFatObesity
Mettauer 2001 J Am Coll Cardiol2001Mettauer B, Zoll J, Sanchez H, Lampert E, Ribera F, Veksler V, Bigard X, Mateo P, Epailly E, Lonsdorfer J, Ventura-Clapier R (2001) Oxidative capacity of skeletal muscle in heart failure patients versus sedentary or active control subjects. J Am Coll Cardiol 38:947-54.HumanSkeletal muscleCardiovascular
Rasmussen 2001 Am J Physiol Endocrinol Metab2001Rasmussen UF, Rasmussen HN, Krustrup P, Quistorff B, Saltin B, Bangsbo J (2001) Aerobic metabolism of human quadriceps muscle: in vivo data parallel measurements on isolated mitochondria. Am J Physiol Endocrinol Metab 280:E301-7.HumanSkeletal muscle
Gallagher 2000 Am J Clin Nutr2000Gallagher D, Heymsfield SB, Heo M, Jebb SA, Murgatroyd PR, Sakamoto Y (2000) Healthy percentage body fat ranges: an approach for developing guidelines based on body mass index. Am J Clin Nutr 72:694-701.HumanFatObesity
Cole 2000 BMJ2000Cole TJ, Bellizzi MC, Flegal KM, Dietz WH (2000) Establishing a standard definition for child overweight and obesity worldwide: international survey. BMJ 320:1240-3.HumanObesity
Zucker 1962 Committee on Biological Handbooks, Fed Amer Soc Exp Biol1962Zucker TF (1962) Regression of standing and sitting weights on body weight: man. In: Growth including reproduction and morphological development. Altman PL, Dittmer DS, eds: Committee on Biological Handbooks, Fed Amer Soc Exp Biol:336-7.Human


Abstracts BME
Sort in ascending/descending order by a click on one of the small symbols in squares below.
Default sorting: chronological. Empty fields appear first in ascending order. 
 YearReferenceOrganismTissue;cellStressDiseases
Gnaiger 2019 MiP20192019
Erich Gnaiger
OXPHOS capacity in human muscle tissue and body mass excess – the MitoEAGLE mission towards an integrative database (Version 6; 2020-01-12).
HumanSkeletal muscleObesity
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Publications MitoEAGLE VO2max/BME data base

Sort in ascending/descending order by a click on one of the small symbols in squares below.
Default sorting: chronological. Empty fields appear first in ascending order. 
 YearReferenceOrganismTissue;cellStressDiseases
Gnaiger 2015 Scand J Med Sci Sports2015Gnaiger E, Boushel R, SĂžndergaard H, Munch-Andersen T, Damsgaard R, Hagen C, DĂ­ez-SĂĄnchez C, Ara I, Wright-Paradis C, Schrauwen P, Hesselink M, Calbet JAL, Christiansen M, Helge JW, Saltin B (2015) Mitochondrial coupling and capacity of oxidative phosphorylation in skeletal muscle of Inuit and caucasians in the arctic winter. https://doi.org/10.1111/sms.12612HumanSkeletal muscleTemperature
Pesta 2011 Am J Physiol Regul Integr Comp Physiol2011Pesta D, Hoppel F, Macek C, Messner H, Faulhaber M, Kobel C, Parson W, Burtscher M, Schocke M, Gnaiger E (2011) Similar qualitative and quantitative changes of mitochondrial respiration following strength and endurance training in normoxia and hypoxia in sedentary humans. Am J Physiol Regul Integr Comp Physiol 301:R1078–87.HumanSkeletal muscleHypoxiaObesity
Raboel 2009 Diabetes Obes Metab2009Raboel R, Hojberg PM, Almdal T, Boushel RC, Haugaard SB, Madsbad S, Dela F (2009) Improved glycaemic control decreases inner mitochondrial membrane leak in type 2 diabetes. Diabetes Obes Metab 11:355-60.HumanSkeletal muscleMitochondrial diseaseDiabetes
Daussin 2008 Am J Physiol Regul Integr Comp Physiol2008Daussin FN, Zoll J, Dufour SP, Ponsot E, Lonsdorfer-Wolf E, Doutreleau S, Mettauer B, Piquard F, Geny B, Richard R (2008) Effect of interval versus continuous training on cardiorespiratory and mitochondrial functions: relationship to aerobic performance improvements in sedentary subjects. Am J Physiol Regul Integr Comp Physiol 295:R264-72.HumanSkeletal muscle
Boushel 2007 Diabetologia2007Boushel RC, Gnaiger E, Schjerling P, Skovbro M, Kraunsoee R, Dela F (2007) Patients with Type 2 diabetes have normal mitochondrial function in skeletal muscle. Diabetologia 50:790-6.HumanSkeletal muscleDiabetes
Obesity
Bakkman 2007 ActaPhysiol2007Bakkman L, Sahlin K, Holmberg HC, Tonkonogi M (2007) Quantitative and qualitative adaptation of human skeletal muscle mitochondria to hypoxic compared with normoxic training at the same relative work rate. Acta Physiol (Oxford) 190:243–51.HumanSkeletal muscleOxidative stress;RONS
Mogensen 2006 J Physiol2006Mogensen M, Bagger M, Pedersen PK, Fernström M, Sahlin K (2006) Cycling efficiency in humans is related to low UCP3 content and to type I fibres but not to mitochondrial efficiency. J Physiol 571:669-81.HumanSkeletal muscle
Ponsot 2006 J Appl Physiol (1985)2006Ponsot E, Dufour SP, Zoll J, Doutrelau S, N'Guessan B, Geny B, Hoppeler H, Lampert E, Mettauer B, Ventura-Clapier R, Richard R (2006) Exercise training in normobaric hypoxia in endurance runners. II. Improvement of mitochondrial properties in skeletal muscle. J Appl Physiol (1985) 100:1249-57.HumanSkeletal muscleHypoxia
Garnier 2005 FASEB J2005Garnier A, Fortin D, Zoll J, N'Guessan B, Mettauer B, Lampert E, Veksler V, Ventura-Clapier R (2005) Coordinated changes in mitochondrial function and biogenesis in healthy and diseased human skeletal muscle. FASEB J 19:43-52.HumanSkeletal muscle
N'Guessan 2004 Mol Cell Biochem2004N'Guessan B, Zoll J, Ribera F, Ponsot E, Lampert E, Ventura-Clapier R, Veksler V, Mettauer B (2004) Evaluation of quantitative and qualitative aspects of mitochondrial function in human skeletal and cardiac muscles. Mol Cell Biochem 256-257:267-80.HumanSkeletal muscle
Rasmussen 2004 Comp Biochem Physiol2004Rasmussen UF, Vielwerth SE, Rasmussen HN (2004) Skeletal muscle bioenergetics: a comparative study of mitochondria isolated from pigeon pectoralis, rat soleus, rat biceps brachii, pig biceps femoris and human quadriceps. Comp Biochem Physiol A Molec Integr Physiol 137:435-46.Human
Pig
Rat
Birds
Skeletal muscle
Rasmussen 2003 Eur J Physiol2003Rasmussen UF, Krustrup P, Kjaer M, Rasmussen HN (2003) Human skeletal muscle mitochondrial metabolism in youth and senescence: no signs of functional changes in ATP formation and mitochondrial oxidative capacity. Pflugers Arch – Eur J Physiol 446:270-78.HumanSkeletal muscleAging;senescence
Zoll 2002 J Physiol2002Zoll J, Sanchez H, N'Guessan B, Ribera F, Lampert E, Bigard X, Surrurier B, Fortin D, Geny B, Veksler V, Ventura-Clapier R, Mettauer B (2002) Physical activity changes the regulation of mitochondrial respiration in human skeletal muscle. J Physiol 543:191-200.HumanSkeletal muscle
Echaniz-Laguna 2002 Ann Neurol2002Echaniz-Laguna A, Zoll J, Ribera F, Tranchant C, Warter JM, Lonsdorfer J, Lampert E (2002) Mitochondrial respiratory chain function in skeletal muscle of ALS patients. Ann Neurol 52:623-7.HumanSkeletal muscleNeurodegenerative
Rasmussen 2001 Pflugers Arch2001Rasmussen UF, Krustrup P, Bangsbo J, Rasmussen HN (2001) The effect of high-intensity exhaustive exercise studied in isolated mitochondria from human skeletal muscle. Pflugers Arch 443:180-7.HumanSkeletal muscle
Mettauer 2001 J Am Coll Cardiol2001Mettauer B, Zoll J, Sanchez H, Lampert E, Ribera F, Veksler V, Bigard X, Mateo P, Epailly E, Lonsdorfer J, Ventura-Clapier R (2001) Oxidative capacity of skeletal muscle in heart failure patients versus sedentary or active control subjects. J Am Coll Cardiol 38:947-54.HumanSkeletal muscleCardiovascular
Rasmussen 2001 Am J Physiol Endocrinol Metab2001Rasmussen UF, Rasmussen HN, Krustrup P, Quistorff B, Saltin B, Bangsbo J (2001) Aerobic metabolism of human quadriceps muscle: in vivo data parallel measurements on isolated mitochondria. Am J Physiol Endocrinol Metab 280:E301-7.HumanSkeletal muscle
Rasmussen 2000 Mol Cell Biochem2000Rasmussen UF, Rasmussen HN (2000) Human quadriceps muscle mitochondria: a functional characterization. Mol Cell Biochem 208:37-44.HumanSkeletal muscle
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Publications BMI

Sort in ascending/descending order by a click on one of the small symbols in squares below.
Default sorting: chronological. Empty fields appear first in ascending order. 
 YearReferenceOrganismTissue;cellStressDiseases
National Academies of Sciences, Engineering, and Medicine 2023 BMI and beyond2023National Academies of Sciences, Engineering, and Medicine (2023) BMI and beyond: Considering context in measuring obesity and its applications: Proceedings of a workshop—in brief. The National Academies Press, Washington, DC https://doi.org/10.17226/27185HumanFatObesity
Wiebe 2021 JAMA Netw Open2021Wiebe N, Ye F, Crumley ET, Bello A, Stenvinkel P, Tonelli M (2021) Temporal associations among body mass index, fasting insulin, and systemic inflammation. A systematic review and meta-analysis. JAMA Netw Open 4:e211263. doi:10.1001/jamanetworkopen.2021.1263.Diabetes
Obesity
Kong 2020 JAMA Netw Open2020Kong L, Nilsson IAK, Brismar K, Gissler M, Lavebratt C (2020) Associations of different types of maternal diabetes and body mass index with offspring psychiatric disorders. JAMA Netw Open 2020 Feb 5;3(2):e1920787.HumanAutism
Diabetes
Neurodegenerative
Obesity
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Skeletal muscle
Gram 2014 Exp Gerontol2014Gram M, Vigelsoe A, Yokota T, Hansen CN, Helge JW, Hey-Mogensen M, Dela F (2014) Two weeks of one-leg immobilization decreases skeletal muscle 2 respiratory capacity equally in young and elderly men. Exp Gerontol 58C:269-78.HumanSkeletal muscleAging;senescence
Mialich 2014 Nutr Hosp2014Mialich MS, Martinez EZ, Jordao JJ (2014) Application of body mass index adjusted for fat mass (BMIfat) obtained by bioelectrical impedance in adults. Nutr Hosp 30:417-24.HumanFatObesity
Dube 2014 Am J Physiol Endocrinol Metab2014Dube JJ, Coen PM, DiStefano G, Chacon AC, Helbling NL, Desimone ME, Stafanovic-Racic M, Hames KC, Despines AA, Toledo FG, Goodpaster BH (2014) Effects of acute lipid overload on skeletal muscle insulin resistance, metabolic flexibility, and mitochondrial performance. Am J Physiol Endocrinol Metab 307:E1117-24.HumanSkeletal muscleDiabetes
Genne-Bacon 2014 Yale J Biol Med2014Genné-Bacon EA (2014) Thinking evolutionarily about obesity. Yale J Biol Med 87:99-112.HumanObesity
Karabatsiakis 2014 Transl Psychiatry2014Karabatsiakis A, Boeck C, Salinas-Manrique J, Kolassa S, Calzia E, Dietrich DE, Kolassa IT (2014) Mitochondrial respiration in peripheral blood mononuclear cells correlates with depressive subsymptoms and severity of major depression. Transl Psychiatry 4:e397.HumanBlood cellsCryopreservationNeurodegenerative
Zeng 2014 Br J Nutr2014Zeng Q, He Y, Dong S, Zhao X, Chen Z, Song Z, Chang G, Yang F, Wang Y (2014) Optimal cut-off values of BMI, waist circumference and waist:height ratio for defining obesity in Chinese adults. Br J Nutr 112:1735-44.HumanCardiovascular
Diabetes
Obesity
Keys 2014 Int J Epidemiol2014Keys A, Fidanza F, Karvonen MJ, Kimura N, Taylor HL (2014) Indices of relative weight and obesity. Int J Epidemiol 43:655-65.HumanFatObesity
Bonthuis 2013 PLOS ONE2013Bonthuis M, Jager KJ, Abu-Hanna A, Verrina E, Schaefer F, van Stralen KJ (2013) Application of body mass index according to height-age in short and tall children. PLOS ONE 8:e72068.Human
Hernandez-Aguilera 2013 Mediators Inflamm2013Hernåndez-Aguilera A, Rull A, Rodríguez-Gallego E, Riera-Borrull M, Luciano-Mateo F, Camps J, Menéndez JA, Joven J (2013) Mitochondrial dysfunction: a basic mechanism in inflammation-related non-communicable diseases and therapeutic opportunities. Mediators Inflamm 2013:135698.HumanFatOxidative stress;RONSObesity
Johnson 2013 Obesity (Silver Spring)2013Johnson RJ, Stenvinkel P, Martin SL, Jani A, SĂĄnchez-Lozada LG, Hill JO, Lanaspa MA (2013) Redefining metabolic syndrome as a fat storage condition based on studies of comparative physiology. Obesity (Silver Spring) 21:659-64.HumanObesity
Andersen 2013 Int J Circumpolar Health2013Andersen S, Fleischer Rex K, Noahsen P, SĂžrensen HC, Mulvad G, Laurberg P (2013) Raised BMI cut-off for overweight in Greenland Inuit--a review. Int J Circumpolar Health 2013 Aug 5;72. doi: 10.3402/ijch.v72i0.21086.Obesity
Dagan 2013 Nutr J2013Dagan SS, Segev S, Novikov I, Dankner R (2013) Waist circumference vs body mass index in association with cardiorespiratory fitness in healthy men and women: a cross sectional analysis of 403 subjects. Nutr J 12:12.Human
Loe 2013 PLOS ONE2013Loe H, Rognmo Ø, Saltin B, WislÞff U (2013) Aerobic capacity reference data in 3816 healthy men and women 20-90 years. PLOS ONE 8:e64319.Human
Setty 2013 Int J Med Sci Public Health2013Setty P, Padmanabha BV, Doddamani BR (2013) Correlation between obesity and cardio respiratory fitness. Int J Med Sci Public Health 2:300-4.HumanObesity
Afolabi 2013 Int J Sci Engin Res2013Afolabi BO, Akanbi OG (2013) Effects of body mass index on aerobic power (VO2max) and energy expenditure (EE): a case of manual load lifting in agro-processing. Int J Sci Engin Res 4:1718-21.Human
Tipton 2012 Nursing2012Tipton PH, Aigner MJ, Finto D, Haislet JA, Pehl L, Sanford P, Williams M (2012) Consider the accuracy of height and weight measurements. Nursing 42:50-2.Human
Thomas 2012 Nutr Res Rev2012Thomas EL, Frost G, Taylor-Robinson SD, Bell JD (2012) Excess body fat in obese and normal-weight subjects. Nutr Res Rev 25:150–61.HumanFatObesity
Phielix 2012 Diabetes2012Phielix E, Meex R, Ouwens DM, Sparks LM, Hoeks J, Schaart G, Moonen-Kornips E, Hesselink MK, Schrauwen P (2012) High oxidative capacity due to chronic exercise training attenuates lipid-induced insulin resistance. Diabetes 61:2472-8.HumanSkeletal muscleMitochondrial diseaseDiabetes
Timmers 2011 Cell Metab2011Timmers S, Konings E, Bilet L, Houtkooper RH, van de Weijer T, Goossens GH, Hoeks J, van der Krieken S, Ryu D, Kersten S, Moonen-Kornips E, Hesselink MK, Kunz I, Schrauwen-Hinderling VB, Blaak EE, Auwerx J, Schrauwen P (2011) Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans. Cell Metab 14:612-22.HumanSkeletal muscleObesity
Misra 2011 Int J Obes (Lond)2011Misra A, Khurana L (2011) Obesity-related non-communicable diseases: South Asians vs White Caucasians. Int J Obes (Lond) 35:167–87.HumanFatCardiovascular
Diabetes
Obesity
Studenski 2011 JAMA2011Studenski Stephanie, Perera Subashan, Patel Kushang, Rosano Caterina, Faulkner Kimberly, Inzitari Marco, Brach Jennifer, Chandler Julie, Cawthon Peggy, Connor Elizabeth Barrett, Nevitt Michael, Visser Marjolein, Kritchevsky Stephen, Badinelli Stefania, Harris Tamara, Newman Anne B, Cauley Jane, Ferrucci Luigi, Guralnik Jack (2011) Gait speed and survival in older adults. JAMA 305:50–8.HumanAging;senescence
Pesta 2011 Am J Physiol Regul Integr Comp Physiol2011Pesta D, Hoppel F, Macek C, Messner H, Faulhaber M, Kobel C, Parson W, Burtscher M, Schocke M, Gnaiger E (2011) Similar qualitative and quantitative changes of mitochondrial respiration following strength and endurance training in normoxia and hypoxia in sedentary humans. Am J Physiol Regul Integr Comp Physiol 301:R1078–87.HumanSkeletal muscleHypoxiaObesity
Bergman 2011 Obesity (Silver Spring)2011Bergman RN, Stefanovski D, Buchanan TA, Sumner AE, Reynolds JC, Sebring NG, Xiang AH, Watanabe RM (2011) A better index of body adiposity. Obesity (Silver Spring) 19:1083-9.HumanFatObesity
Chomentowski 2011 J Clin Endocrinol Metab2011Chomentowski P, Coen PM, RadikovĂĄ Z, Goodpaster BH, Toledo FG (2011) Skeletal muscle mitochondria in insulin resistance: Differences in intermyofibrillar versus subsarcolemmal subpopulations and relationship to metabolic flexibility. J Clin Endocrinol Metab 96: 494-503.HumanSkeletal muscleDiabetes
Obesity
Meeuwsen 2010 Clin Nutr2010Meeuwsen S, Horgan GW, Elia M (2010) The relationship between BMI and percent body fat, measured by bioelectrical impedance, in a large adult sample is curvilinear and influenced by age and sex. Clin Nutr 29:560-6.HumanFatAging;senescence
Obesity
Pribis 2010 Nutrients2010Pribis P, Burtnack CA, McKenzie SO, Thayer J (2010) Trends in body fat, body mass index and physical fitness among male and female college students. Nutrients 2:1075-85.HumanObesity
So 2010 J Sports Sci Med2010So WY, Choi DH (2010) Differences in physical fitness and cardiovascular function depend on BMI in Korean men. J Sports Sci Med 9:239-44.Human
Wang 2010 Biomed Environ Sci2010Wang C, Hou XH, Zhang ML, Bao YQ, Zou YH, Zhong WH, Xiang KS, Jia WP (2010) Comparison of body mass index with body fat percentage in the evaluation of obesity in Chinese. Biomed Environ Sci 23:173-9.HumanDiabetes
Obesity
Volkow 2009 Obesity (Silver Spring)2009Volkow ND, Wang GJ, Telang F, Fowler JS, Goldstein RZ, Alia-Klein N, Logan J, Wong C, Thanos PK, Ma Y, Pradhan K (2009) Inverse association between BMI and prefrontal metabolic activity in healthy adults. Obesity (Silver Spring) 17:60-5.HumanNervous systemObesity
Walley 2009 Nat Rev Genet2009Walley AJ, Asher JE, Froguel P (2009) The genetic contribution to non-syndromic human obesity. Nat Rev Genet 10:431–42.HumanObesity
Raboel 2009 Diabetes Obes Metab2009Raboel R, Hojberg PM, Almdal T, Boushel RC, Haugaard SB, Madsbad S, Dela F (2009) Improved glycaemic control decreases inner mitochondrial membrane leak in type 2 diabetes. Diabetes Obes Metab 11:355-60.HumanSkeletal muscleMitochondrial diseaseDiabetes
Gnaiger 2009 Int J Biochem Cell Biol2009Gnaiger E (2009) Capacity of oxidative phosphorylation in human skeletal muscle. New perspectives of mitochondrial physiology. https://doi.org/10.1016/j.biocel.2009.03.013Human
Mouse
Skeletal muscleAging;senescence
Obesity
Bosy-Westphal 2009 Br J Nutr2009Bosy-Westphal A, Plachta-Danielzik S, Dörhöfer RP, MĂŒller MJ (2009) Short stature and obesity: positive association in adults but inverse association in children and adolescents. Br J Nutr 102:453-61.FatObesity
Misra 2009 J Assoc Physicians India2009Misra A, Chowbey P, Makkar BM, Vikram NK, Wasir JS, Chadha D, Joshi Shashank R, Sadikot S, Gupta R, Gulati Seema, Munjal YP, Concensus Group (2009) Consensus statement for diagnosis of obesity, abdominal obesity and the metabolic syndrome for Asian Indians and recommendations for physical activity, medical and surgical management. J Assoc Physicians India 57:163–70.HumanFatCardiovascular
Diabetes
Obesity
Cohen 2008 Am J Clin Nutr2008Cohen DA, Sturm R (2008) Body mass index is increasing faster among taller persons. Am J Clin Nutr 87:445-8.HumanObesity
Romero-Corral 2008 Int J Obes (Lond)2008Romero-Corral A, Somers VK, Sierra-Johnson J, Thomas RJ, Collazo-Clavell ML, Korinek J, Allison TG, Batsis JA, Sert-Kuniyoshi FH, Lopez-Jimenez F (2008) Accuracy of body mass index in diagnosing obesity in the adult general population. Int J Obes (Lond) 32:959-66.HumanFatObesity
Nakhostin-Roohi 2008 J Sports Med Phys Fitness2008Nakhostin-Roohi B, Niknam Z (2008) BMI, fat percentage and VO2max in college female staff. J Sports Med Phys Fitness 48:211-6.Human
Daussin 2008 Am J Physiol Regul Integr Comp Physiol2008Daussin FN, Zoll J, Dufour SP, Ponsot E, Lonsdorfer-Wolf E, Doutreleau S, Mettauer B, Piquard F, Geny B, Richard R (2008) Effect of interval versus continuous training on cardiorespiratory and mitochondrial functions: relationship to aerobic performance improvements in sedentary subjects. Am J Physiol Regul Integr Comp Physiol 295:R264-72.HumanSkeletal muscle
Brien 2007 Can J Public Health2007Brien SE, Katzmarzyk PT, Craig CL, Gauvin L (2007) Physical activity, cardiorespiratory fitness and body mass index as predictors of substantial weight gain and obesity: the Canadian physical activity longitudinal study. Can J Public Health 98:121-4..HumanObesity
Barquera 2007 Int J Obes (Lond)2007Barquera S, Peterson KE, Must A, Rogers BL, Flores M, Houser R, Monterrubio E, Rivera-Dommarco JA (2007) Coexistence of maternal central adiposity and child stunting in Mexico. Int J Obes (Lond) 31:601-7.HumanObesity
Joshi 2007 JAMA2007Joshi P, Islam S, Pais P, Reddy S, Dorairaj P, Kazmi K, Pandey MR, Haque S, Mendis S, Rangarajan S, Yusuf S (2007) Risk factors for early myocardial infarction in South Asians compared with individuals in other countries. JAMA 297:286-94.HumanCardiovascular
Obesity
Boushel 2007 Diabetologia2007Boushel RC, Gnaiger E, Schjerling P, Skovbro M, Kraunsoee R, Dela F (2007) Patients with Type 2 diabetes have normal mitochondrial function in skeletal muscle. Diabetologia 50:790-6.HumanSkeletal muscleDiabetes
Obesity
De Onis 2007 Bull World Health Organization2007de Onis M, Onyango AW, Borghi E, Siyam A, Nishida C, Siekmann J (2007) Development of a WHO growth reference for school-aged children and adolescents. Bull World Health Organization 85:660-7.HumanObesity
Rabinovich 2007 Eur Respir J2007Rabinovich RA, Bastos R, Ardite E, LlinĂ s L, Orozco-Levi M, Gea J, VilarĂł J, BarberĂ  JA, RodrĂ­guez-Roisin R, FernĂĄndez-Checa JC, Roca J (2007) Mitochondrial dysfunction in COPD patients with low body mass index. Eur Respir J 29:643-50.HumanSkeletal muscleOxidative stress;RONS
Heymsfield 2007 Am J Clin Nutr2007Heymsfield SB, Gallagher D, Mayer L, Beetsch J, Pietrobelli A (2007) Scaling of human body composition to stature: new insights into body mass index. Am J Clin Nutr 86:82-91.HumanSkeletal muscle
Nervous system
Liver
Fat
Obesity
Bakkman 2007 ActaPhysiol2007Bakkman L, Sahlin K, Holmberg HC, Tonkonogi M (2007) Quantitative and qualitative adaptation of human skeletal muscle mitochondria to hypoxic compared with normoxic training at the same relative work rate. Acta Physiol (Oxford) 190:243–51.HumanSkeletal muscleOxidative stress;RONS
Wells 2007 Biol Rev Camb Philos Soc2007Wells JC (2007) The thrifty phenotype as an adaptive maternal effect. Biol Rev Camb Philos Soc 82:143-72.HumanObesity
WHO 2006 Geneva: World Health Organization2006WHO Multicentre Growth Reference Study Group (2006) WHO child growth standards: length/height-for-age, weight-for-age, weight-for-length, weight-for-height and body mass index-for-age: Methods and development. Geneva: World Health Organization 312 pp.HumanObesity
Wells 2006 Biol Rev Camb Philos Soc2006Wells JC (2006) The evolution of human fatness and susceptibility to obesity: an ethological approach. Biol Rev Camb Philos Soc 81:183-205.HumanObesity
Mogensen 2006 J Physiol2006Mogensen M, Bagger M, Pedersen PK, Fernström M, Sahlin K (2006) Cycling efficiency in humans is related to low UCP3 content and to type I fibres but not to mitochondrial efficiency. J Physiol 571:669-81.HumanSkeletal muscle
Ponsot 2006 J Appl Physiol (1985)2006Ponsot E, Dufour SP, Zoll J, Doutrelau S, N'Guessan B, Geny B, Hoppeler H, Lampert E, Mettauer B, Ventura-Clapier R, Richard R (2006) Exercise training in normobaric hypoxia in endurance runners. II. Improvement of mitochondrial properties in skeletal muscle. J Appl Physiol (1985) 100:1249-57.HumanSkeletal muscleHypoxia
Dufour 2006 J Appl Physiol (1985)2006Dufour SP, Ponsot E, Zoll J, Doutreleau S, Lonsdorfer-Wolf E, Geny B, Lampert E, FlĂŒck M, Hoppeler H, Billat V, Mettauer B, Richard R, Lonsdorfer J (2006) Exercise training in normobaric hypoxia in endurance runners. I. Improvement in aerobic performance capacity. J Appl Physiol (1985) 100:1238-48.HumanHypoxia
WHO 2006 Acta Paediatr2006WHO Multicentre Growth Reference Study Group (2006) WHO Child Growth Standards based on length/height, weight and age. Acta Paediatr Suppl 450:76-85.Human
Garnier 2005 FASEB J2005Garnier A, Fortin D, Zoll J, N'Guessan B, Mettauer B, Lampert E, Veksler V, Ventura-Clapier R (2005) Coordinated changes in mitochondrial function and biogenesis in healthy and diseased human skeletal muscle. FASEB J 19:43-52.HumanSkeletal muscle
Diverse Populations Collaborative Group 2005 Am J Phys Anthropol2005Diverse Populations Collaborative Group (2005) Weight-height relationships and body mass index: some observations from the Diverse Populations Collaboration. Am J Phys Anthropol 128:220-9.Human
WHO Expert Consultation 2004 Lancet2004WHO Expert Consultation (2004) Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies. Lancet 363:157-63.HumanObesity
N'Guessan 2004 Mol Cell Biochem2004N'Guessan B, Zoll J, Ribera F, Ponsot E, Lampert E, Ventura-Clapier R, Veksler V, Mettauer B (2004) Evaluation of quantitative and qualitative aspects of mitochondrial function in human skeletal and cardiac muscles. Mol Cell Biochem 256-257:267-80.HumanSkeletal muscle
Rasmussen 2003 Eur J Physiol2003Rasmussen UF, Krustrup P, Kjaer M, Rasmussen HN (2003) Human skeletal muscle mitochondrial metabolism in youth and senescence: no signs of functional changes in ATP formation and mitochondrial oxidative capacity. Pflugers Arch – Eur J Physiol 446:270-78.HumanSkeletal muscleAging;senescence
Echaniz-Laguna 2002 Ann Neurol2002Echaniz-Laguna A, Zoll J, Ribera F, Tranchant C, Warter JM, Lonsdorfer J, Lampert E (2002) Mitochondrial respiratory chain function in skeletal muscle of ALS patients. Ann Neurol 52:623-7.HumanSkeletal muscleNeurodegenerative
Colin 2002 Am J Epidemiol2002Colin Bell A, Adair LS, Popkin BM (2002) Ethnic differences in the association between body mass index and hypertension. Am J Epidemiol 155:346-53.HumanCardiovascular
Obesity
Zoll 2002 J Physiol2002Zoll J, Sanchez H, N'Guessan B, Ribera F, Lampert E, Bigard X, Surrurier B, Fortin D, Geny B, Veksler V, Ventura-Clapier R, Mettauer B (2002) Physical activity changes the regulation of mitochondrial respiration in human skeletal muscle. J Physiol 543:191-200.HumanSkeletal muscle
Chen 2002 Obes Rev2002Chen W, Lin CC, Peng CT, Li CI, Wu HC, Chiang J, Wu JY, Huang PC (2002) Approaching healthy body mass index norms for children and adolescents from health-related physical fitness. Obes Rev 3:225-32.HumanObesity
Mettauer 2001 J Am Coll Cardiol2001Mettauer B, Zoll J, Sanchez H, Lampert E, Ribera F, Veksler V, Bigard X, Mateo P, Epailly E, Lonsdorfer J, Ventura-Clapier R (2001) Oxidative capacity of skeletal muscle in heart failure patients versus sedentary or active control subjects. J Am Coll Cardiol 38:947-54.HumanSkeletal muscleCardiovascular
Deurenberg 2001 Eur J Clin Nutr2001Deurenberg P, Andreoli A, Borg P, Kukkonen-Harjula K, de Lorenzo A, van Marken Lichtenbelt WD, Testolin G, Vigano R, Vollaard N (2001) The validity of predicted body fat percentage from body mass index and from impedance in samples of five European populations. Eur J Clin Nutr 55:973-9.HumanFatObesity
Rasmussen 2001 Am J Physiol Endocrinol Metab2001Rasmussen UF, Rasmussen HN, Krustrup P, Quistorff B, Saltin B, Bangsbo J (2001) Aerobic metabolism of human quadriceps muscle: in vivo data parallel measurements on isolated mitochondria. Am J Physiol Endocrinol Metab 280:E301-7.HumanSkeletal muscle
Cole 2000 BMJ2000Cole TJ, Bellizzi MC, Flegal KM, Dietz WH (2000) Establishing a standard definition for child overweight and obesity worldwide: international survey. BMJ 320:1240-3.HumanObesity
WHO 2000 Sydney Health Comm AU2000WHO Regional Office for the Western Pacific (2000) The Asia-Pacific perspective: redefining obesity and its treatment. World Health Organization Western Pacific Region 55 pp.HumanObesity
Gallagher 2000 Am J Clin Nutr2000Gallagher D, Heymsfield SB, Heo M, Jebb SA, Murgatroyd PR, Sakamoto Y (2000) Healthy percentage body fat ranges: an approach for developing guidelines based on body mass index. Am J Clin Nutr 72:694-701.HumanFatObesity
Wei 1999 JAMA1999Wei M, Kampert JB, Barlow CE, Nichaman MZ, Gibbons LW, Paffenbarger RS Jr, Blair SN (1999) Relationship between low cardiorespiratory fitness and mortality in normal-weight, overweight, and obese men. JAMA 282:1547-53.HumanCardiovascular
Diabetes
Obesity
Zucker 1962 Committee on Biological Handbooks, Fed Amer Soc Exp Biol1962Zucker TF (1962) Regression of standing and sitting weights on body weight: man. In: Growth including reproduction and morphological development. Altman PL, Dittmer DS, eds: Committee on Biological Handbooks, Fed Amer Soc Exp Biol:336-7.Human
Neel 1962 Am J Hum Genet1962Neel JV (1962) Diabetes mellitus: a "thrifty" genotype rendered detrimental by "progress"? Am J Hum Genet 14:353-62.HumanObesity
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 YearReferenceOrganismTissue;cellStressDiseases
Calabria 2023 Biomedicines2023Calabria E, Muollo V, Cavedon V, Capovin T, Saccenti L, Passarotti F, Ghiotto L, Milanese C, Gelati M, Rudi D, Salvagno GL, Lippi G, Tam E, Schena F, Pogliaghi S (2023) Type 2 diabetes related mitochondrial defects in peripheral mononucleated blood cells from overweight postmenopausal women. https://doi.org/10.3390/biomedicines11010121HumanBlood cellsDiabetes
Hadanny 2022 Sports Med Open2022Hadanny A, Hachmo Y, Rozali D, Catalogna M, Yaakobi E, Sova M, Gattegno H, Abu Hamed R, Lang E, Polak N, Friedman M, Finci S, Zemel Y, Bechor Y, Gal N, Efrati S (2022) Effects of hyperbaric oxygen therapy on mitochondrial respiration and physical performance in middle-aged athletes: a blinded, randomized controlled trial.HumanSkeletal muscle
PĂŒhringer 2021 High Alt Med Biol2021PĂŒhringer R, Gatterer H, Berger M, Said M, Faulhaber M, Burtscher M (2021) Does moderate altitude affect VO2max in acclimatized mountain guides? High Alt Med Biol doi: 10.1089/ham.2021.0081HumanHypoxia
Chambers 2020 J Appl Physiol (1985)2020Chambers TL, Burnett TR, Raue U, Lee GA, Finch WH, Graham BM, Trappe TA, Trappe S (2020) Skeletal muscle size, function, and adiposity with lifelong aerobic exercise. J Appl Physiol (1985) 128:368–78.HumanSkeletal muscle
Fat
Aging;senescence
Caspi 2020 J Am Heart Assoc2020Caspi T, Straw S, Cheng C, Garnham JO, Scragg JL, Smith J, Koshy AO, Levelt E, Sukumar P, Gierula J, Beech DJ, Kearney MT, Cubbon RM, Wheatcroft SB, Witte KK, Roberts LD, Bowen TS (2020) Unique transcriptome signature distinguishes patients with heart failure with myopathy. J Am Heart Assoc 9:e017091. https://doi.org/10.1161/JAHA.120.017091HumanHeart
Skeletal muscle
Cardiovascular
Myopathy
Murthy 2020 JAMA Cardiol2020Murthy VL, Xia R, Baldridge AS, Carnethon MR, Sidney S, Bouchard C, Sarzynski MA, Lima JAC, Lewis GD, Shah SJ, Fornage M, Shah RV (2020) Polygenic risk, fitness, and obesity in the Coronary Artery Risk Development In Young Adults (CARDIA) study. JAMA Cardiol 5:40-8. doi: 10.1001/jamacardio.2019.5220HumanCardiovascular
Obesity
Hunter 2019 J Appl Physiol (1985)2019Hunter GR, Moellering DR, Windham ST, Mathis SL, Bamman MM, Fisher G (2019) Relationship between VO2max, cycle economy & mitochondrial respiration in untrained/trained. J Appl Physiol (1985) 127:1562-68.HumanSkeletal muscle
Hunter 2019 J Appl Physiol2019Hunter GR, Moellering DR, Windham ST, Mathis SL, Bamman MM, Fisher G (2019) Relationship between V̇o2peak, cycle economy, and mitochondrial respiration in untrained/trained. J Appl Physiol 127:1562-8.HumanSkeletal muscle
Chroeis 2019 Eur J Sport Sci2019ChrĂžis KM, Dohlmann TL, SĂžgaard D, Hansen CV, Dela F, Helge JW, Larsen S (2019) Mitochondrial adaptations to high intensity interval training in older females and males. Eur J Sport Sci 20:135-45.HumanSkeletal muscleAging;senescence
Cardinale 2019 Front Physiol2019Cardinale DA, Larsen FJ, LÀnnerström J, Manselin T, SödergÄrd O, Mijwel S, Lindholm P, Ekblom B, Boushel R (2019) Influence of hyperoxic-supplemented high-intensity interval training on hemotological and muscle mitochondrial adaptations in trained cyclists. Front Physiol 10:730.HumanSkeletal muscle
Allard 2018 J Clin Endocrinol Metab2018Allard NAE, Schirris TJJ, Verheggen RJ, Russel FGM, Rodenburg RJ, Smeitink JAM, Thompson PD, Hopman MTE, Timmers S (2018) Statins affect skeletal muscle performance: evidence for disturbances in energy metabolism. J Clin Endocrinol Metab 103:75-84.HumanSkeletal muscleMyopathy
Distefano 2018 J Cachexia Sarcopenia Muscle2018Distefano G, Standley RA, Zhang X, Carnero EA, Yi F, Cornnell HH, Coen PM (2018) Physical activity unveils the relationship between mitochondrial energetics, muscle quality, and physical function in older adults. J Cachexia Sarcopenia Muscle 9:279-94.HumanSkeletal muscleAging;senescence
Cardinale 2018 Front Physiol2018Cardinale DA, Larsen FJ, Schiffer TA, Morales-Alamo D, Ekblom B, Calbet JAL, Holmberg HC, Boushel R (2018) Superior intrinsic mitochondrial respiration in women than in men. Front Physiol 9:1133.HumanSkeletal muscle
Gonzalez-Freire 2018 Aging Cell2018Gonzalez-Freire M, Scalzo P, D'Agostino J, Moore ZA, Diaz-Ruiz A, Fabbri E, Zane A, Chen B, Becker KG, Lehrmann E, Zukley L, Chia CW, Tanaka T, Coen PM, Bernier M, de Cabo R, Ferrucci L (2018) Skeletal muscle ex vivo mitochondrial respiration parallels decline in vivo oxidative capacity, cardiorespiratory fitness, and muscle strength: the Baltimore longitudinal study of aging. Aging Cell 17.HumanSkeletal muscleAging;senescence
Robach 2018 Scand J Med Sci Sports2018Robach P, Hansen J, Pichon A, Meinild Lundby AK, Dandanell S, SlettalÞkken Falch G, Hammarström D, Pesta DH, Siebenmann C, Keiser S, Kérivel P, Whist JE, RÞnnestad BR, Lundby C (2018) Hypobaric live high-train low does not improve aerobic performance more than live low-train low in cross-country skiers. Scand J Med Sci Sports 28:1636-52.HumanSkeletal muscleHypoxia
Lund 2018 Acta Physiol (Oxf)2018Lund MT, Larsen S, Hansen M, Courraud J, Floyd AK, StĂžckel M, Helge JW, Dela F (2018) Mitochondrial respiratory capacity remains stable despite a comprehensive and sustained increase in insulin sensitivity in obese patients undergoing gastric bypass surgery. Acta Physiol (Oxf) 223:e13032.HumanSkeletal muscleDiabetes
Obesity
Asping 2017 Eur J Clin Pharmacol2017Asping M, Stride N, SĂžgaard D, Dohlmann TL, Helge JW, Dela F, Larsen S (2017) The effects of 2 weeks of statin treatment on mitochondrial respiratory capacity in middle-aged males: the LIFESTAT study. Eur J Clin Pharmacol 73:679-87.Human
Lalia 2017 Aging (Albany NY)2017Lalia AZ, Dasari S, Robinson MM, Abid H, Morse DM, Klaus KA, Lanza IR (2017) Influence of omega-3 fatty acids on skeletal muscle protein metabolism and mitochondrial bioenergetics in older adults. Aging (Albany NY) 9:1096-1129.HumanSkeletal muscleAging;senescence
Goedecke 2017 JMIR Res Protoc2017Goedecke JH, Mendham AE, Clamp L, Nono Nankam PA, Fortuin-de Smidt MC, Phiri L, Micklesfield LK, Keswell D, Woudberg NJ, Lecour S, Alhamud A, Kaba M, Lutomia FM, van Jaarsveld PJ, de Villiers A, Kahn SE, Chorell E, Hauksson J, Olsson T (2017) An exercise intervention to unravel the mechanisms underlying insulin resistance in a cohort of black South African women: Protocol for a randomized controlled trial. JMIR Res Protoc 03/10/2017:9098.HumanSkeletal muscle
Fat
Diabetes
Obesity
Kenny 2017 Diabetologia2017Kenny HC, Rudwill F, Breen L, Salanova M, Blottner D, Heise T, Heer M, Blanc S, O'Gorman DJ (2017) Bed rest and resistive vibration exercise unveil novel links between skeletal muscle mitochondrial function and insulin resistance. Diabetologia 60:1491-501.HumanSkeletal muscleDiabetes
Wu 2017 Sci Rep2017Wu LH, Chang SC, Fu TC, Huang CH, Wang JS (2017) High-intensity interval training improves mitochondrial function and suppresses thrombin generation in platelets undergoing hypoxic stress. Sci Rep 7:4191.HumanBlood cells
Platelet
Hypoxia
Greggio 2017 Cell Metab2017Greggio C, Jha P, Kulkarni SS, Lagarrigue S, Broskey NT, Boutant M, Wang X, Alonso SC, Ofori E, Auwerx J, CantĂł C, Amati F (2017) Enhanced respiratory chain supercomplex formation in response to exercise in human skeletal muscle. Cell Metab 25:301-11.HumanSkeletal muscle
Mondal 2017 J Clin Diagn Res2017Mondal H, Mishra SP (2017) Effect of BMI, body fat percentage and fat free mass on maximal oxygen consumption in healthy young adults. J Clin Diagn Res 11:CC17-20.HumanObesity
Nabben 2017 Am J Physiol Regul Integr Comp Physiol2017Nabben M, Schmitz JP, Ciapaite J, Le Clercq CM, van Riel NA, Haak HR, Nicolay K, de Coo IF, Smeets HJ, Praet SF, van Loon LJ, Prompers JJ (2017) Dietary nitrate does not reduce oxygen cost of exercise or improve muscle mitochondrial function in mitochondrial myopathy patients. Am J Physiol Regul Integr Comp Physiol 312:689-701.HumanSkeletal muscleMyopathy
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