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News and Events | Working Groups | Short-Term Scientific Missions | Management Committee | Members |
COST Action CA15203 (2016-2021): MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping
Larsen Filip J
MitoPedia topics: EAGLE
Name | Larsen Filip J, Dr.
Assistant Professor |
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Institution |
GIH Swedish School of Sport and Health Sciences |
Address | Box 5626, Room 1239, 114 86 |
City | Stockholm |
State/Province | |
Country | Sweden |
filip.larsen@ki.se | |
Weblink | |
O2k-Network Lab | SE Stockholm Larsen FJ, SE Stockholm Sahlin K |
Labels:
Publications
Published | Reference | |
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Flockhart 2023 Redox Biol | 2023 | Flockhart M, Nilsson LC, Tillqvist EN, Vinge F, Millbert F, Lännerström J, Nilsson PH, Samyn D, Apró W, Sundqvist ML, Larsen FJ (2023) Glucosinolate-rich broccoli sprouts protect against oxidative stress and improve adaptations to intense exercise training. https://doi.org/10.1016/j.redox.2023.102873 |
Horwath 2022 J Physiol | 2022 | Horwath O, Edman S, Andersson A, Larsen FJ, Apró W (2022) THRIFTY: a novel high-throughput method for rapid fibre type identification of isolated skeletal muscle fibres. https://doi.org/10.1113/jp282959 |
Flockhart 2021 Cell Metab | 2021 | Flockhart M, Nilsson LC, Tais S, Ekblom B, Apro W, Larsen FJ (2021) Excessive exercise training causes mitochondrial functional impairment and decreases glucose tolerance in healthy volunteers. Cell Metab 33:957-70. |
Cardinale 2021 J Appl Physiol (1985) | 2021 | Cardinale DA, Gejl KD, Petersen KG, Nielsen J, Ørtenblad N, Larsen FJ (2021) Short-term intensified training temporarily impairs mitochondrial respiratory capacity in elite endurance athletes. J Appl Physiol (1985) 131:388-400. |
Larsen 2020 Acta Physiol (Oxf) | 2020 | Larsen FJ, Schiffer TA, Zinner C, Willis SJ, Morales-Alamo D, Calbet J, Boushel R, Holmberg HC (2020) Mitochondrial oxygen affinity increases after sprint interval training and is related to the improvement in peak oxygen uptake. https://doi.org/10.1111/apha.13463 |
Cardinale 2019 Front Physiol | 2019 | Cardinale DA, Larsen FJ, Lännerström J, Manselin T, Södergård O, Mijwel S, Lindholm P, Ekblom B, Boushel R (2019) Influence of hyperoxic-supplemented high-intensity interval training on hemotological and muscle mitochondrial adaptations in trained cyclists. Front Physiol 10:730. |
Cardinale 2018 Physiol Rep | 2018 | Cardinale DA, Gejl KD, Ørtenblad N, Ekblom B, Blomstrand E, Larsen FJ (2018) Reliability of maximal mitochondrial oxidative phosphorylation in permeabilized fibers from the vastus lateralis employing high-resolution respirometry. Physiol Rep 6. doi: 10.14814/phy2.13611. |
Cardinale 2018 Acta Physiol (Oxf) | 2018 | Cardinale DA, Larsen FJ, Jensen-Urstad M, Rullman E, Søndergaard H, Morales-Alamo D, Ekblom B, Calbet JAL, Boushel R (2018) Muscle mass and inspired oxygen influence oxygen extraction at maximal exercise: Role of mitochondrial oxygen affinity. Acta Physiol (Oxf) 225:e13110. |
Cardinale 2018 Front Physiol | 2018 | Cardinale DA, Larsen FJ, Schiffer TA, Morales-Alamo D, Ekblom B, Calbet JAL, Holmberg HC, Boushel R (2018) Superior intrinsic mitochondrial respiration in women than in men. Front Physiol 9:1133. |
Cardinale 2017 Front Physiol | 2017 | Cardinale DA, Lilja M, Mandić M, Gustafsson T, Larsen FJ, Lundberg TR (2017) Resistance training with co-ingestion of anti-inflammatory drugs attenuates mitochondrial function. Front Physiol 8:1074. |
Zinner 2016 Front Physiol | 2016 | Zinner C, Morales-Alamo D, Ørtenblad N, Larsen FJ, Schiffer TA, Willis SJ, Gelabert-Rebato M, Perez-Valera M, Boushel R, Calbet JA, Holmberg HC (2016) The physiological mechanisms of performance enhancement with sprint interval training fiffer between the upper and lower extremities in humans. Front Physiol 7:426. |
Larsen 2016 FASEB J | 2016 | Larsen FJ, Schiffer TA, Ørtenblad N, Zinner C, Morales-Alamo D, Willis SJ, Calbet JA, Holmberg HC, Boushel R (2016) High-intensity sprint training inhibits mitochondrial respiration through aconitase inactivation. FASEB J 30:417-27. |
Schiffer 2016 Am J Physiol Cell Physiol | 2016 | Schiffer TA, Peleli M, Sundqvist ML, Ekblom B, Lundberg JO, Weitzberg E, Larsen FJ (2016) Control of human energy expenditure by cytochrome c oxidase subunit IV-2. Am J Physiol Cell Physiol 311:C452-61. |
Hezel 2015 Redox Biol | 2015 | Hezel MP, Liu M, Schiffer TA, Larsen FJ, Checa A, Wheelock CE, Carlström M, Lundberg JO, Weitzberg E (2015) Effects of long-term dietary nitrate supplementation in mice. Redox Biol 5:234-42. |
Boushel 2015 Scand J Med Sci Sports | 2015 | Boushel R, Gnaiger E, Larsen FJ, Helge JW, Gonzalez-Alonso J, Ara I, Munch-Andersen T, van Hall G, Søndergaard H, Saltin B, Calbet JAL (2015) Maintained peak leg and pulmonary VO2 despite substantial reduction in muscle mitochondrial capacity. Scand J Med Sci Sports 25 (Suppl 4):135–43. |
Larsen 2014 Am J Clin Nutr | 2014 | Larsen FJ, Schiffer TA, Ekblom B, Mattsson MP, Checa A, Wheelock CE, Nyström T, Lundberg JO, Weitzberg E (2014) Dietary nitrate reduces resting metabolic rate: a randomized, crossover study in humans. Am J Clin Nutr 99:843-50. |
Soltysinska 2014 PLoS One | 2014 | Soltysinska E, Bentzen BH, Barthmes M, Hattel H, Thrush AB, Harper ME, Qvortrup K, Larsen FJ, Schiffer TA, Losa-Reyna J, Straubinger J, Kniess A, Thomsen MB, Brüggemann A, Fenske S, Biel M, Ruth P, Wahl-Schott C, Boushel RC, Olesen SP, Lukowski R (2014) KCNMA1 encoded cardiac BK channels afford protection against ischemia-reperfusion injury. PLoS One 9:e103402. |
Schiffer 2014 FASEB J | 2014 | Schiffer TA, Ekblom B, Lundberg JO, Weitzberg E, Larsen FJ (2014) Dynamic regulation of metabolic efficiency explains tolerance to acute hypoxia in humans. FASEB J 28:4303-11. |
Larsen 2012 Eur J Appl Physiol | 2012 | Larsen FJ, Ekblom B (2012) The low intracellular oxygen tension during exercise is a function of limited oxygen supply and high mitochondrial oxygen affinity. Eur J Appl Physiol 112:3935-6. |
Larsen 2011 Cell Metab | 2011 | Larsen FJ, Schiffer TA, Borniquel S, Sahlin K, Ekblom B, Lundberg JO, Weitzberg E (2011) Dietary inorganic nitrate improves mitochondrial efficiency in humans. Cell Metab 13:149-59. |
Larsen 2011 FASEB J | 2011 | Larsen FJ, Schiffer TA, Sahlin K, Ekblom B, Weitzberg E, Lundberg JO (2011) Mitochondrial oxygen affinity predicts basal metabolic rate in humans. FASEB J 25:2843-52. doi:10.1096/fj.11-182139 |
Abstracts
Published | Reference | |
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Edman 2023 Abstract IOC160 | 2023 | Edman S, Flockhart M, Larsen FJ, Apro W (2023) Need for Speed: Human fast-twitch mitochondria favor power over efficiency. Mitochondr Physiol Network 28.01. |
Schiffer 2013 Abstract MiP2013 | 2013 | Schiffer TA, Weitzberg E, Lundberg JO, Larsen FJ (2013) Dietary inorganic nitrate reduces basal metabolic rate in man. Mitochondr Physiol Network 18.08. |
Larsen FJ 2013 Abstract MiP2013 | 2013 | Larsen FJ, Schiffer TA, Lundberg JO, Weitzberg E (2013) Human mitochondria has a unique response to ischemia-reperfusion injury compared to mitochondria from rat, mouse and pig . Mitochondr Physiol Network 18.08. |