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NextGen-O2k

From Bioblast
Revision as of 15:26, 13 May 2019 by Gnaiger C (talk | contribs)

Template:MitoFit highlights page name The revolutionary all-in-one instrument to conquer mitochondrial disease NextGen-O2k

Mission

Oroboros - as a driving force in mitochondrial physiology - extends the analytical and diagnostic power of high-resolution respirometry by integration of NADH- and Q-redox monitoring in the NextGen-O2k. We aim at establishing the Oroboros quality control management for dissemination to our worldwide O2k-Network laboratories. This will become an effective contribution to address the acute reproducibility crisis of scientific investigation. In the spirit of Open Science and global networking, we will enable data sharing across projects and institutions in an Open Access database on mitochondrial physiology and pathology, to resolve the inflation crisis and ultimately the value-impact crisis of present academic publication. This will support key developments in mitochondrial medicine. In addition, we expand our business to biotechnology and ecology with the photobiology module of the NextGen-O2k, widening our focus from medicine to environment and climate.


Gentle Science

In addition to O2k-Workshops and on-site training, Oroboros will disseminate the not-for-profit initiatives on Mitochondrial Physiology and Bioenergetics Science Camps, specialized Mitochondrial Physiology Conferences, and Preprint publications:
» Oroboros is a key player in support of the COST Action MitoEAGLE
» MitoGlobal - the world-wide platform for societies and organizations supporting mitochondrial research and medicine
» MitoEAGLE with cooperation by Oroboros launched MitoFit Preprint Archives - the preprint server for mitochondrial physiology and bioenergetics
» A vision on preprints
» Mitochondrial respiratory states and rates : >530 coauthors join forces towards harmonization on nomenclature
» Gentle Science - recognizes the responsibility of the scientific community - for the quality of science, the quality of life in science, and its mission


NextGen-O2k H2020-SMEInst

NextGen-O2k
  • Horizon 2020 Framework Programme Proposal: 859770 — NextGen-O2k
  • EIC-SMEInst-2018-2020 — SME instrument phase 2
  • The project NextGen-O2k is supported by the Standortagentur Tyrol and the FFG (Österreichische Forschungsförderungsgesellschaft)
  • Duration of the action: 24 months
  • Partners: About Oroboros, WGT Elektronik, SHTech, software security networks.
  • Application: 2019-01-09 ; Granted: 2019-03-05 Start: 2019-06-01 (total budget € 2.35Mil)



O2k

High-resolution respirometry (HRR) and unique combinations of the O2k with
Oroboros products timeline.jpg


NextGen-O2k

Extend high-resolution respirometry (HRR) to the all-in-one device
  • (+1) Cyclic voltammetry: the Q-redox sensor
(+2) Controlled wavelengths and light intensity: PhotoBiology module
  • Save on experimental time, reagents and samples
  • Minimize errors and ensure reproducible and accurate results
  • Highest oxygen sensitivity (5 nM detection limit)
  • Exceptional resolution (wide oxygen concentration range, between 0 - 1,000 μM)
  • Robustness (>10 years lifespan)
Respiration and photosynthesis.png


Top 10 reasons for Oroboros.jpg



NextGen-O2k modules.jpg

MitoFit

MitoEAGLE Q-workshop


Open positions