Moisoi Nicoleta

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BEC 2020.1 Mitochondrial physiology
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COST Action CA15203 (2016-2021): MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping

Moisoi Nicoleta

MitoPedia topics: EAGLE 

COST: Member

COST WG4: WG4 COST Mentor: Mentor

WG4 Leader - Management Committee MitoEAGLE

Name Moisoi Nicoleta, Dr.
Nicoleta Moisoi
Leicester School of Pharmacy,

Faculty of Health Sciences,

De Montfort University, UK

Address The Gateway

Hawthorn Building 1.03, LE1 9BH

City Leicester
Country United Kingdom
O2k-Network Lab UK Cambridge Martins LM, UK Leicester Giorgini F, UK Leicester Moisoi N

Bioenergetics Communications

Keywords: animal models, cell models, mitochondria-nucleus crosstalk, neurodegeneration, signaling

Participated at


        • Benefits for COST and for the COST Action MitoEAGLE
My current research focuses on the role of mitochondria in neurodegenerative disease, particularly in Parkinson's disease.

Labels: Field of research: Basic 


Temelie 2023 Int J Mol Sci2023Temelie M, Talpur R, Dominguez-Prieto M, Dantas Silva A, Cenusa C, Craciun L, Savu DI, Moisoi N (2023) Impaired integrated stress response and mitochondrial integrity modulate genotoxic stress impact and lower the threshold for immune signalling.
Ebanks 2023 PLoS One2023Ebanks B, Kwiecinska P, Moisoi N, Chakrabarti L (2023) A method to assess the mitochondrial respiratory capacity of complexes I and II from frozen tissue using the Oroboros O2k-FluoRespirometer.
Krako Jakovljevic 2021 BEC PD2021Krako Jakovljevic N, Ebanks B, Katyal G, Chakrabarti L, Markovic I, Moisoi N (2021) Mitochondrial homeostasis in cellular models of Parkinson’s Disease. Bioenerg Commun 2021.2.
BEC 2020.1 doi10.26124bec2020-0001.v12020Gnaiger E et al ― MitoEAGLE Task Group (2020) Mitochondrial physiology. Bioenerg Commun 2020.1.
Temelie 2018 Oxid Med Cell Longev2018Temelie M, Savu DI, Moisoi N (2018) Intracellular and intercellular signalling mechanisms following DNA damage are modulated by PINK1. Oxid Med Cell Longev 1391387.
Pimenta 2012 Cell Death Differ2012Pimenta de Castro I, Costa AC, Lam D, Tufi R, Fedele V, Moisoi N, Dinsdale D, Deas E, Loh SH, Martins LM (2012) Genetic analysis of mitochondrial protein misfolding in Drosophila melanogaster. Cell Death Differ doi:10.1038/cdd.2012.5.
Moisoi 2009 Cell Death Differ2009Moisoi N, Klupsch K, Fedele V, East P, Sharma S, Renton A, Plun-Favreau H, Edwards RE, Teismann P, Esposti MD, Morrison AD, Wood NW, Downward J, Martins LM (2009) Mitochondrial dysfunction triggered by loss of HtrA2 results in the activation of a brain-specific transcriptional stress response. Cell Death Differ 16:449-64.


Ebanks 2022 Abstract Bioblast2022P09.
Brad Ebanks
Ebanks Brad, Wang Y, Katyal G, Sargent C, Ingram TL, Bowman A, Moisoi N, Chakrabarti L (2022) Exercise alters mitochondrial physiology and has age-specific impacts on the fitness and lifespan of D. melanogaster. Bioblast 2022: BEC Inaugural Conference. In:
Moisoi 2019 MiP20192019
Nicoletta Moisoi
The integrated stress response mediates mitochondria-nucleus communication in neurodegeneration.
Moisoi 2018 MiP2018a2018
Nicoleta Moisoi
Mitochondria-nucleus communication: Who talks first? Who talks louder?
Moisoi 2018 MiP2018b2018
Nicoleta Moisoi
Integrating published data of mitochondrial function in cell lines as models of neurodegenerative disease.
Moisoi 2017 Abstract MITOEAGLE Barcelona2017
Mitochondrial quality control signaling in Parkinson’s disease models.
Moisoi 2017 MiP20172017
Nicoleta Moisoi
Mitochondria-nucleus communication. Linking Parkinson’s related mitochondrial dysfunction with DNA damage signaling.
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