Difference between revisions of "Oroboros Laboratory"
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{{Template:OROBOROS header page name}} | {{Template:OROBOROS header page name}} | ||
:::: <big>''' | {{Template:OROBOROS Slogan}} | ||
[[File: | |||
[[ | :::: <big>'''Scientists with a gentle touch of entrepreneurship'''</big> | ||
[[File:Lab in action.jpg|right|500px|Oroboros Laboratory]] | |||
<!--[[File:OROBOROS MitoFit-Lab.jpg|left|240px |Oroboros O2k-Laboratory]]--> | |||
__TOC__ | __TOC__ | ||
:::: The '''Oroboros | == Oroboros O2k-Laboratory == | ||
:::: '''42 O2k-Chambers (21 O2k)''' | |||
:::: The '''Oroboros O2k-Laboratory''' ('Mitochondriales Forschungslabor') is a scientific research laboratory in Innsbruck, Austria, and likely the best equipped lab for high-resolution respirometry (HRR) worldwide. The O2k-Lab was opened during the course of the K-Regio project [[MitoCom_O2k-Fluorometer| MitoCom Tyrol]] in June 2013. It comprises 140 sqm which are divided into the office and research areas. | |||
::::* | ::::* Twenty-one O2k instruments for HRR (42 chambers) equipped with automatic Titration-Injection microPumps and the newest O2k-MultiSensor Modules or the NextGen-O2k configuration are available for research and biomedical applications. The newest instrumental designs are used for rigorous testing of our innovations. | ||
::::* Two additional O2ks (4 chambers) are devoted to instrumental development. | ::::* Two additional O2ks (4 chambers) are devoted to instrumental development. | ||
::::* According to the concept of open innovation, the | ::::* According to the concept of open innovation, the Oroboros O2k-Laboratory welcomes visiting researchers from all over the world. | ||
::::» ''More details:'' [[O2k-technical_support_and_open_innovation|Oroboros Support]] | ::::» ''More details:'' [[O2k-technical_support_and_open_innovation|Oroboros Support]] | ||
=== | === Joint projects === | ||
:::: ''' | {| style="color: black; width: 90%" | ||
|- | |||
| style="text-align: left; background-color: #EFF5FB" | '''[[Functional Mitochondrial Diagnostics]]''' (VASCage) | |||
| style="text-align: center; background-color: #ffffff" | | |||
<gallery heights="165px" mode="nolines" perrow="4" widths="192px"> | |||
File:Hardorp Rebecka.jpg|'''[[Hardorp Rebecka|Rebecka Hardorp]]''' | |||
File:Romero Martinez Alejandra.jpeg|'''[[Romero Martinez Alejandra|Alejandra Romero-Martinez, Dr.]]''' | |||
File:Wieser-Insole J.jpg|'''[[Wieser-Insole Joshua|Joshua Wieser-Insole]]''' | |||
</gallery> | |||
|- | |||
| style="text-align: left; background-color: #ffffff" | '''[[ALAS]]''' | |||
| style="text-align: center; background-color: #EFF5FB" | | |||
<gallery heights="165px" mode="nolines" perrow="4" widths="192px"> | |||
File:Profile-icon-9.png|'''[[Pfleger Ana|Ana Pfleger, Mag. ]]''' | |||
File:Roach_T.jpg|'''[[Roach Thomas|Thomas Roach, PhD ]]''' | |||
</gallery> | |||
|- | |||
| style="text-align: left; background-color: #EFF5FB" | '''[[TissueModels]]''' | |||
| style="text-align: center; background-color: #ffffff" | | |||
<gallery heights="165px" mode="nolines" perrow="4" widths="192px"> | |||
File:Keller M.PNG|'''[[Keller Markus A| Markus Keller, Dr.]]''' | |||
File:IOC 2366 cropped.jpg|'''[[Smaling Anna|Anna Smaling, MRes]]''' | |||
:::: | </gallery> | ||
:: | |- | ||
| style="text-align: left; background-color: #ffffff" | '''[[MitoKIN]]''' | |||
| style="text-align: center; background-color: #EFF5FB" | | |||
<gallery heights="165px" mode="nolines" perrow="4" widths="192px"> | |||
File:Stefan E.jpg|'''[[Stefan Eduard|Eduard Stefan, PhD]]''' | |||
File:Profile-icon-9.png|'''[[Strich Sophie|Sophie Strich]]''' | |||
File:Torres-QuesadaO.jpg|'''[[Torres-Quesada O|Omar Torres-Quesada, PhD]]''' | |||
</gallery> | |||
|- | |||
| style="text-align: left; background-color: #EFF5FB" | '''[[CureMILS]]''' | |||
| style="text-align: center; background-color: #ffffff" | | |||
<gallery heights="165px" mode="nolines" perrow="4" widths="192px"> | |||
File:Suarez.png|'''[[Suarez-Cubero Marta|Marta Suarez-Cubero]]''' | |||
</gallery> | |||
|} | |||
== OXPHOS analysis == | |||
:::: SUIT protocols are applied in tissue samples from animal models and human patients. Using cultured cells or cells extracted from blood samples, the effects of genotypic variations or of various drugs are studied on OXPHOS parameters, using | :::: SUIT protocols are applied in tissue samples from animal models and human patients. Using cultured cells or cells extracted from blood samples, the effects of genotypic variations or of various drugs are studied on OXPHOS parameters, using | ||
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::::» [[ | ::::» [[Projects|'''Current projects''']] | ||
::::» '''[[Partners in the Oroboros Ecosystem]]''' | |||
::::» [[ | ::::» [[Oroboros Laboratories: visiting scientists |'''Visiting scientists''']] | ||
== Keywords == | |||
{{Keywords: Oroboros Laboratories}} | |||
Latest revision as of 16:58, 15 February 2024
Oroboros Laboratory
- Mitochondria and Cell Research - the Oroboros Ecosystem
- Scientists with a gentle touch of entrepreneurship
Oroboros O2k-Laboratory
- 42 O2k-Chambers (21 O2k)
- The Oroboros O2k-Laboratory ('Mitochondriales Forschungslabor') is a scientific research laboratory in Innsbruck, Austria, and likely the best equipped lab for high-resolution respirometry (HRR) worldwide. The O2k-Lab was opened during the course of the K-Regio project MitoCom Tyrol in June 2013. It comprises 140 sqm which are divided into the office and research areas.
- Twenty-one O2k instruments for HRR (42 chambers) equipped with automatic Titration-Injection microPumps and the newest O2k-MultiSensor Modules or the NextGen-O2k configuration are available for research and biomedical applications. The newest instrumental designs are used for rigorous testing of our innovations.
- Two additional O2ks (4 chambers) are devoted to instrumental development.
- According to the concept of open innovation, the Oroboros O2k-Laboratory welcomes visiting researchers from all over the world.
- » More details: Oroboros Support
Joint projects
| Functional Mitochondrial Diagnostics (VASCage) |
|
| ALAS |
|
| TissueModels |
|
| MitoKIN |
|
| CureMILS |
|
OXPHOS analysis
- SUIT protocols are applied in tissue samples from animal models and human patients. Using cultured cells or cells extracted from blood samples, the effects of genotypic variations or of various drugs are studied on OXPHOS parameters, using
- coupling control protocols (CCP) in intact cells to evaluate effects on ROUTINE respiration, biochemical coupling efficiency and extracellular ROS production under physiological conditions;
- various substrate-uncoupler-inhibitor titration (SUIT) protocols in permeabilized cells for deep OXPHOS phenotyping (cell ergometry).
Keywords
- Bioblast links: Oroboros Laboratory - >>>>>>> - Click on [Expand] or [Collapse] - >>>>>>>
