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From Bioblast
 YearReferenceOrganismTissue;cellStressDiseases
Hunter-Manseau 2024 Insect Sci2024Hunter-Manseau F, Cormier SB, Strang R, Pichaud N (2024) Fasting as a precursor to high-fat diet enhances mitochondrial resilience in Drosophila melanogaster. Insect Sci [Epub ahead of print]. https://doi.org/10.1111/1744-7917.13355Drosophila
Kim 2024 J Exerc Rehabil2024Kim TW, Park SS, Kim SH, Kim MK, Shin MS, Kim SH (2024) Exercise before pregnancy exerts protective effect on prenatal stress-induced impairment of memory, neurogenesis, and mitochondrial function in offspring. J Exerc Rehabil 20:2-10. https://doi.org/10.12965/jer.2448068.034MouseNervous system
Xiao 2024 Sci Adv2024Xiao L, Yin Y, Sun Z, Liu J, Jia Y, Yang L, Mao Y, Peng S, Xie Z, Fang L, Li J, Xie X, Gan Z (2024) AMPK phosphorylation of FNIP1 (S220) controls mitochondrial function and muscle fuel utilization during exercise. Sci Adv 10:eadj2752. https://doi.org/10.1126/sciadv.adj2752MouseSkeletal muscle
Cefis 2024 Acta Physiol (Oxf)2024Cefis M, Dargegen M, Marcangeli V, Taherkhani S, Dulac M, Leduc-Gaudet JP, Mayaki D, Hussain SNA, Gouspillou G (2024) MFN2 overexpression in skeletal muscles of young and old mice causes a mild hypertrophy without altering mitochondrial respiration and H2O2 emission. Acta Physiol (Oxf) [Epub ahead of print]. https://doi.org/10.1111/apha.14119MouseSkeletal muscleAging;senescence
Donnelly 2024 Redox Biol2024Donnelly C, Komlódi T, Cecatto C, Cardoso LHD, Compagnion A-C, Matera A, Tavernari D, Campiche O, Paolicelli RC, Zanou N, Kayser B, Gnaiger E, Place N (2024) Functional hypoxia reduces mitochondrial calcium uptake. Redox Biol 71:103037. https://doi.org/10.1016/j.redox.2024.103037Human
Mouse		Heart
Skeletal muscle		Hypoxia
Hu 2024 Front Endocrinol (Lausanne)2024Hu Y, Fang B, Tian X, Wang H, Tian X, Yu F, Li T, Yang Z, Shi R (2024) Passive exercise is an effective alternative to HRT for restoring OVX induced mitochondrial dysfunction in skeletal muscle. Front Endocrinol (Lausanne) 15:1356312. https://doi.org/10.3389/fendo.2024.1356312MouseSkeletal muscle
Fitzgerald 2024 J Cachexia Sarcopenia Muscle2024Fitzgerald LF, Lackey J, Moussa A, Shah SV, Castellanos AM, Khan S, Schonk M, Thome T, Salyers ZR, Jakkidi N, Kim K, Yang Q, Hepple RT, Ryan TE (2024) Chronic aryl hydrocarbon receptor activity impairs muscle mitochondrial function with tobacco smoking. https://doi.org/10.1002/jcsm.13439MouseSkeletal muscleCOPD
Qiao 2024 J Sport Health Sci2024Qiao YS, Blackwell TL, Cawthon PM, Coen PM, Cummings SR, Distefano G, Farsijani S, Forman DE, Goodpaster BH, Kritchevsky SB, Mau T, Toledo FGS, Newman AB, Glynn NW (2024) Associations of accelerometry-measured and self-reported physical activity and sedentary behavior with skeletal muscle energetics: The Study of Muscle, Mobility and Aging (SOMMA). https://doi.org/10.1016/j.jshs.2024.02.001HumanSkeletal muscleAging;senescence
Dreher 2023 Int J Obes (Lond)2023Dreher SI, Irmler M, Pivovarova-Ramich O, Kessler K, Jürchott K, Sticht C, Fritsche L, Schneeweiss P, Machann J, Pfeiffer AFH, Hrabě de Angelis M, Beckers J, Birkenfeld AL, Peter A, Niess AM, Weigert C, Moller A (2023) Acute and long-term exercise adaptation of adipose tissue and skeletal muscle in humans: a matched transcriptomics approach after 8-week training-intervention. https://doi.org/10.1038/s41366-023-01271-yHumanSkeletal muscle
Fat		Obesity
Heo 2023 J Cachexia Sarcopenia Muscle2023Heo J, Schifino AG, McFaline-Figueroa J, Miller DL, Hoffman JR, Noble EE, Greising SM, Call JA (2023) Differential effects of Western diet and traumatic muscle injury on skeletal muscle metabolic regulation in male and female mice. https://doi.org/10.1002/jcsm.13361MouseSkeletal muscleObesity
Other
Colosio 2023 J Appl Physiol (1985)2023Colosio M, Brocca L, Gatti M, Neri M, Crea E, Cadile F, Canepari M, Pellegrino MA, Polla B, Porcelli S, Bottinelli R (2023) Structural and functional impairments of skeletal muscle in patients with post-acute sequelae of SARS-CoV-2 infection. https://doi.org/10.1152/japplphysiol.00158.2023HumanSkeletal muscleInfectious
Frangos 2023 J Biol Chem2023Frangos SM, DesOrmeaux GJ, Holloway GP (2023) Acidosis attenuates CPT-I supported bioenergetics as a potential mechanism limiting lipid oxidation. https://doi.org/10.1016/j.jbc.2023.105079MouseSkeletal muscle
Wang 2023 Nature2023Wang D, Townsend LK, DesOrmeaux GJ, Frangos SM, Batchuluun B, Dumont L, Kuhre RE, Ahmadi E, Hu S, Rebalka IA, Gautam J, Jabile MJT, Pileggi CA, Rehal S, Desjardins EM, Tsakiridis EE, Lally JSV, Juracic ES, Tupling AR, Gerstein HC, Paré G, Tsakiridis T, Harper ME, Hawke TJ, Speakman JR, Blondin DP, Holloway GP, Jørgensen SB, Steinberg GR (2023) GDF15 promotes weight loss by enhancing energy expenditure in muscle. https://doi.org/10.1038/s41586-023-06249-4MouseSkeletal muscleObesity
Diaz 2023 Front Mol Biosci2023Diaz EC, Adams SH, Weber JL, Cotter M, Børsheim E (2023) Elevated LDL-C, high blood pressure, and low peak V˙O2 associate with platelet mitochondria function in children-The Arkansas Active Kids Study. Front Mol Biosci 10:1136975. https://doi.org/10.3389/fmolb.2023.1136975HumanBlood cells
Platelet		Aging;senescence
Mancilla 2023 Physiol Rep2023Mancilla R, Pava-Mejia D, van Polanen N, de Wit V, Bergman M, Grevendonk L, Jorgensen J, Kornips E, Hoeks J, Hesselink MKC, Schrauwen-Hinderling VB (2023) Invasive and noninvasive markers of human skeletal muscle mitochondrial function. https://doi.org/10.14814/phy2.15734HumanSkeletal muscle
Stampley 2023 Physiol Rep2023Stampley JE, Cho E, Wang H, Theall B, Johannsen NM, Spielmann G, Irving BA (2023) Impact of maximal exercise on immune cell mobilization and bioenergetics. https://doi.org/10.14814/phy2.15753HumanBlood cells
Scandalis 2023 JAMA Cardiol2023Scandalis L, Kitzman DW, Nicklas BJ, Lyles M, Brubaker P, Nelson MB, Gordon M, Stone J, Bergstrom J, Neufer PD, Gnaiger E, Molina AJA (2023) Skeletal muscle mitochondrial respiration and exercise intolerance in patients with heart failure with preserved ejection fraction. https://doi.org/10.1001/jamacardio.2023.0957HumanSkeletal muscleCardiovascular
Donnelly 2023 MitoFit2023Donnelly C, Komlódi T, Cecatto C, Cardoso LHD, Compagnion AC, Matera A, Tavernari D, Zanou N, Kayser B, Gnaiger E, Place N (2023) Functional hypoxia reduces mitochondrial calcium uptake. MitoFit Preprints 2023.2. https://doi.org/10.26124/mitofit:2023-0002 — 2024-11-17 published in Redox Biol.Human
Mouse		Skeletal muscle
Heart
Nervous system
Other cell lines		Hypoxia
Kyriazis 2023 Res Sq2023Kyriazis G, Serrano J, Boyd J, Mason C, Smith K, Karolyi K, Kondo S, Brown I, Maurya S, Meshram N, Serna V, Gilger J, Branch D, Gardell S, Baskin K, Ayala J, Pratley R, Goodpaster B, Coen P (2023) The TAS1R2 sweet taste receptor regulates skeletal muscle mass and fitness. https://doi.org/10.21203/rs.3.rs-2475555/v1MouseSkeletal muscleAging;senescence
Obesity
Davis 2023 Am J Physiol Regul Integr Comp Physiol .2023Davis MS, Bayly WM, Hansen CM, Barrett MR, Blake CA (2023) Effects of hyperthermia and acidosis on mitochondrial production of reactive oxygen species. Am J Physiol Regul Integr Comp Physiol . 325(6):R725-R734.HorseSkeletal muscleTemperature
Thoral 2023 J Exp Biol2023Thoral E, Roussel D, Gasset E, Dutto G, Queiros Q, McKenzie DJ, Bourdeix JH, Metral L, Saraux C, Teulier L (2023) Temperature-dependent metabolic consequences of food deprivation in the European sardine. https://doi.org/10.1242/jeb.244984FishesSkeletal muscle
Marin 2023 Exp Gerontol2023Marin CT, de Souza Lino AD, Avelar IDS, Barbosa MR, Scarlato GCG, Cavalini DF, Tamanini F, Alexandrino AV, Vercesi AE, Shiguemoto GE (2023) Resistance training prevents dynamics and mitochondrial respiratory dysfunction in vastus lateralis muscle of ovariectomized rats. https://doi.org/10.1016/j.exger.2023.112081RatSkeletal muscle
Garcia-Roche 2023 PLoS One2023García-Roche M, Talmón D, Cañibe G, Astessiano AL, Mendoza A, Cassina A, Quijano C, Carriquiry M (2023) Hepatic metabolism of grazing cows of two Holstein strains under two feeding strategies with different levels of pasture inclusion. https://doi.org/10.1371/journal.pone.0290551BovinesLiver
Chen 2023 Nat Commun2023Chen M, Zhu JY, Mu WJ, Luo HY, Li Y, Li S, Yan LJ, Li RY, Guo L (2023) Cdo1-Camkk2-AMPK axis confers the protective effects of exercise against NAFLD in mice. https://doi.org/10.1038/s41467-023-44242-7HumanLiverOther
Sharma 2023 Biosci Biotechnol Biochem2023Sharma S, Zhang X, Azhar G, Patyal P, Verma A, Kc G, Wei JY (2023) Valine improves mitochondrial function and protects against oxidative stress. https://doi.org/10.1093/bbb/zbad169MouseSkeletal muscleOxidative stress;RONS
Noone 2023 J Physiol2023Noone J, Damiot A, Kenny H, Chery I, Zahariev A, Normand S, Crampes F, de Glisezinski I, Rochfort KD, Laurens C, Bareille MP, Simon C, Bergouignan A, Blanc S, O'Gorman DJ (2023) The impact of 60 days of -6° head down tilt bed rest on mitochondrial content, respiration and regulators of mitochondrial dynamics. https://doi.org/10.1113/jp284734HumanSkeletal muscle
Harmsen 2023 J Physiol2023Harmsen JF, Kotte M, Habets I, Bosschee F, Frenken K, Jorgensen JA, de Kam S, Moonen-Kornips E, Cissen J, Doligkeit D, van de Weijer T, Erazo-Tapia E, Buitinga M, Hoeks J, Schrauwen P (2023) Exercise training modifies skeletal muscle clock gene expression but not 24-hour rhythmicity in substrate metabolism of men with insulin resistance. https://doi.org/10.1113/jp285523HumanSkeletal muscleDiabetes
Obesity
Wen 2023 PLoS One2023Wen W, Guo C, Chen Z, Yang D, Zhu D, Jing Q, Zheng L, Sun C, Tang C (2023) Regular exercise attenuates alcoholic myopathy in zebrafish by modulating mitochondrial homeostasis. https://doi.org/10.1371/journal.pone.0294700ZebrafishSkeletal muscleMyopathy
Bodis 2023 Diabetes Obes Metab2023Bódis K, Breuer S, Crepzia-Pevzner A, Zaharia OP, Schön M, Saatmann N, Altenhofen D, Springer C, Szendroedi J, Wagner R, Al-Hasani H, Roden M, Pesta D, Chadt A (2023) Impact of physical fitness and exercise training on subcutaneous adipose tissue beiging markers in humans with and without diabetes and a high-fat diet-fed mouse model. https://doi.org/10.1111/dom.15322MouseFatDiabetes
Jiang 2023 Sci Rep2023Jiang N, Wang Z, Guo X, Peng Z, He Y, Wang Q, Wu H, Cui Y (2023) Hepatic Runx1t1 improves body fat index after endurance exercise in obese mice. https://doi.org/10.1038/s41598-023-46302-wMouseLiverObesity
Batterson 2023 Physiol Rep2023Batterson PM, McGowan EM, Borowik AK, Kinter MT, Miller BF, Newsom SA, Robinson MM (2023) High-fat diet increases electron transfer flavoprotein synthesis and lipid respiration in skeletal muscle during exercise training in female mice. https://doi.org/10.14814/phy2.15840MouseSkeletal muscle
Ismaeel 2023 Physiol Rep2023Ismaeel A, Valentino TR, Burke B, Goh J, Saliu TP, Albathi F, Owen A, McCarthy JJ, Wen Y (2023) Acetate and succinate benefit host muscle energetics as exercise-associated post-biotics. https://doi.org/10.14814/phy2.15848MouseSkeletal muscle
Nijholt 2023 Sci Rep2023Nijholt KT, Sánchez-Aguilera PI, Mahmoud B, Gerding A, Wolters JC, Wolters AHG, Giepmans BNG, Silljé HHW, de Boer RA, Bakker BM, Westenbrink BD (2023) A Kinase Interacting Protein 1 regulates mitochondrial protein levels in energy metabolism and promotes mitochondrial turnover after exercise. https://doi.org/10.1038/s41598-023-45961-zMouseHeart
Spagnuolo 2022 Mol Neurobiol2022Spagnuolo MS, Mazzoli A, Nazzaro M, Troise AD, Gatto C, Tonini C, Colardo M, Segatto M, Scaloni A, Pallottini V, Iossa S, Cigliano L (2022) Long-lasting Impact of sugar intake on neurotrophins and neurotransmitters from adolescence to young adulthood in rat frontal cortex. https://doi.org/10.1007/s12035-022-03115-8RatNervous system
Broome 2022 Redox Biol2022Broome SC, Pham T, Braakhuis AJ, Narang R, Wang HW, Hickey AJR, Mitchell CJ, Merry TL (2022) MitoQ supplementation augments acute exercise-induced increases in muscle PGC1α mRNA and improves training-induced increases in peak power independent of mitochondrial content and function in untrained middle-aged men. https://doi.org/10.1016/j.redox.2022.102341HumanSkeletal muscle
Cho 2022 BMC Med2022Cho J, Johnson BD, Watt KD, Niven AS, Yeo D, Kim CH (2022) Exercise training attenuates pulmonary inflammation and mitochondrial dysfunction in a mouse model of high-fat high-carbohydrate-induced NAFLD. https://doi.org/10.1186/s12916-022-02629-1MouseLung;gillOther
Donnelly 2022 BEC2022Donnelly C, Schmitt S, Cecatto C, Cardoso LHD, Komlódi T, Place N, Kayser B, Gnaiger E (2022) The ABC of hypoxia – what is the norm. Bioenerg Commun 2022.12.v2. https://doi.org/10.26124/bec:2022-0012.v2Oxidative stress;RONS
Hypoxia
Kullmann 2022 JCI Insight2022Kullmann S, Goj T, Veit R, Fritsche L, Wagner L, Schneeweiss P, Hoene M, Hoffmann C, Machann J, Niess A, Preissl H, Birkenfeld AL, Peter A, Häring HU, Fritsche A, Moller A, Weigert C, Heni M (2022) Exercise restores brain insulin sensitivity in sedentary adults who are overweight and obese. https://doi.org/10.1172/jci.insight.161498Obesity
Zhu 2022 Metabolism2022Zhu JY, Chen M, Mu WJ, Luo HY, Guo L (2022) Higd1a facilitates exercise-mediated alleviation of fatty liver in diet-induced obese mice. https://doi.org/10.1016/j.metabol.2022.155241MouseLiverObesity
Other
McKenna 2022 J Appl Physiol (1985)2022McKenna CF, Salvador AF, Keeble AR, Khan NA, De Lisio M, Konopka AR, Paluska SA, Burd NA (2022) Muscle strength after resistance training correlates to mediators of muscle mass and mitochondrial respiration in middle-aged adults. https://doi.org/10.1152/japplphysiol.00186.2022HumanSkeletal muscle
Trewin 2022 BMC Biol2022Trewin AJ, Silver J, Dillon HT, Della Gatta PA, Parker L, Hiam DS, Lee YP, Richardson M, Wadley GD, Lamon S (2022) Long non-coding RNA Tug1 modulates mitochondrial and myogenic responses to exercise in skeletal muscle. https://doi.org/10.1186/s12915-022-01366-4MouseSkeletal muscle
Laehteenmaeki 2022 Physiol Rep2022Lähteenmäki EI, Koski M, Koskela I, Lehtonen E, Kankaanpää A, Kainulainen H, Walker S, Lehti M (2022) Resistance exercise with different workloads have distinct effects on cellular respiration of peripheral blood mononuclear cells. https://doi.org/10.14814/phy2.15394HumanBlood cells
Dias 2022 Free Radic Biol Med2022Dias C, Lourenço CF, Laranjinha J, Ledo A (2022) Modulation of oxidative neurometabolism in ischemia/reperfusion by nitrite. https://doi.org/10.1016/j.freeradbiomed.2022.11.021RatNervous systemIschemia-reperfusion
De Goede 2022 FASEB J2022de Goede P, Wüst RCI, Schomakers BV, Denis S, Vaz FM, Pras-Raves ML, van Weeghel M, Yi CX, Kalsbeek A, Houtkooper RH (2022) Time-restricted feeding during the inactive phase abolishes the daily rhythm in mitochondrial respiration in rat skeletal muscle. FASEB J 36:e22133.RatSkeletal muscleDiabetes
Jelenik 2022 Pharmacol Res2022Jelenik T, Kodde A, Pesta D, Phielix E, Oosting A, Rohbeck E, Dewidar B, Mastrototaro L, Trenkamp S, Keijer J, van der Beek EM, Roden M (2022) Dietary lipid droplet structure in postnatal life improves hepatic energy and lipid metabolism in a mouse model for postnatal programming. https://doi.org/10.1016/j.phrs.2022.106193MouseSkeletal muscle
Liver
Pileggi 2022 EBioMedicine2022Pileggi CA, Blondin DP, Hooks BG, Parmar G, Alecu I, Patten DA, Cuillerier A, O'Dwyer C, Thrush AB, Fullerton MD, Bennett SAL, Doucet É, Haman F, Cuperlovic-Culf M, McPherson R, Dent RRM, Harper ME (2022) Exercise training enhances muscle mitochondrial metabolism in diet-resistant obesity. https://doi.org/10.1016/j.ebiom.2022.104192HumanSkeletal muscleObesity
Donnelly 2022 MitoFit Hypoxia2022Donnelly C, Schmitt S, Cecatto C, Cardoso LHD, Komlodi T, Place N, Kayser B, Gnaiger E (2022) The ABC of hypoxia – what is the norm. https://doi.org/10.26124/mitofit:2022-0025.v2 — 2022-11-14 published in Bioenerg Commun 2022.12.Oxidative stress;RONS
Hypoxia
Chinas 2022 Metabolites2022Chiñas Merlin A, Gonzalez K, Mockler S, Perez Y, Jia UA, Chicco AJ, Ullevig SL, Chung E (2022) Switching to a standard chow diet at weaning improves the effects of maternal and postnatal high-fat and high-sucrose diet on cardiometabolic health in adult male mouse offspring. https://doi.org/10.3390/metabo12060563MouseHeartCardiovascular
Heimler 2022 BEC2022Heimler SR, Phang HJ, Bergstrom J, Mahapatra G, Dozier S, Gnaiger E, Molina AJA (2022) Platelet bioenergetics are associated with resting metabolic rate and exercise capacity in older adult women. Bioenerg Commun 2022.2. https://doi.org/10.26124/bec:2022-0002HumanBlood cells
Niemann 2022 Biology (Basel)2022Niemann B, Pan R, Issa H, Simm A, Schulz R, Rohrbach S (2022) AMPK activation is indispensable for the protective effects of caloric restriction on left ventricular function in postinfarct myocardium. https://doi.org/10.3390/biology11030448Mouse
Rat		HeartIschemia-reperfusion
Greenwood 2022 BMC Nephrol2022Greenwood SA, Beckley-Hoelscher N, Asgari E, Ayis S, Baker LA, Banerjee D, Bhandari S, Bramham K, Chilcot J, Burton J, Kalra PA, Lightfoot CJ, McCafferty K, Mercer TH, Okonko DO, Oliveira B, Reid C, Smith AC, Swift PA, Mangelis A, Watson E, Wheeler DC, Wilkinson TJ, Reid F, Macdougall IC (2022) The effect of intravenous iron supplementation on exercise capacity in iron-deficient but not anaemic patients with chronic kidney disease: study design and baseline data for a multicentre prospective double-blind randomised controlled trial. https://doi.org/10.1186/s12882-022-02896-3HumanSkeletal muscleOther
Wagner 2022 J Muscle Res Cell Motil2022Wagner PD (2022) Determinants of maximal oxygen consumption. https://doi.org/10.1007/s10974-022-09636-y
Lemminger 2022 Antioxidants (Basel)2022Lemminger AK, Fiorenza M, Eibye K, Bangsbo J, Hostrup M (2022) High-intensity exercise training alters the effect of N-acetylcysteine on exercise-related muscle ionic shifts in men. https://doi.org/10.3390/antiox12010053HumanSkeletal muscle
Hansen 2022 Free Radic Biol Med2022Hansen C, Møller S, Ehlers T, Wickham KA, Bangsbo J, Gliemann L, Hellsten Y (2022) Redox balance in human skeletal muscle-derived endothelial cells - Effect of exercise training. https://doi.org/10.1016/j.freeradbiomed.2021.12.265HumanEndothelial;epithelial;mesothelial cell
Sumbalova 2022 Front Mol Biosci2022Sumbalová Z, Kucharská J, Rausová Z, Palacka P, Kovalčíková E, Takácsová T, Mojto V, Navas P, Lopéz-Lluch G, Gvozdjáková A (2022) Reduced platelet mitochondrial respiration and oxidative phosphorylation in patients with post COVID-19 syndrome are regenerated after spa rehabilitation and targeted ubiquinol therapy. https://doi.org/10.3389/fmolb.2022.1016352HumanPlateletOther
Damgaard 2022 iScience2022Damgaard MV, Nielsen TS, Basse AL, Chubanava S, Trost K, Moritz T, Dellinger RW, Larsen S, Treebak JT (2022) Intravenous nicotinamide riboside elevates mouse skeletal muscle NAD+ without impacting respiratory capacity or insulin sensitivity. https://doi.org/10.1016/j.isci.2022.103863MouseSkeletal muscle
Hadanny 2022 Sports Med Open2022Hadanny A, Hachmo Y, Rozali D, Catalogna M, Yaakobi E, Sova M, Gattegno H, Abu Hamed R, Lang E, Polak N, Friedman M, Finci S, Zemel Y, Bechor Y, Gal N, Efrati S (2022) Effects of hyperbaric oxygen therapy on mitochondrial respiration and physical performance in middle-aged athletes: a blinded, randomized controlled trial.HumanSkeletal muscle
De Jong 2022 Nutrients2022De Jong NP, Rudolph MC, Jackman MR, Sharp RR, Jones K, Houck J, Pan Z, Reusch JEB, MacLean PS, Bessesen DH, Bergouignan A (2022) Short-term adaptations in skeletal muscle mitochondrial oxidative capacity and metabolic pathways to breaking up sedentary behaviors in overweight or obese adults. https://doi.org/10.3390/nu14030454HumanSkeletal muscleObesity
Bikman 2022 Eur J Clin Nutr2022Bikman BT, Shimy KJ, Apovian CM, Yu S, Saito ER, Walton CM, Ebbeling CB, Ludwig DS (2022) A high-carbohydrate diet lowers the rate of adipose tissue mitochondrial respiration. https://doi.org/10.1038/s41430-022-01097-3HumanFat
Remie 2021 Diabetologia2021Remie CME, Janssens GE, Bilet L, van Weeghel M, Duvivier BMFM, de Wit VHW, Connell NJ, Jörgensen JA, Schomakers BV, Schrauwen-Hinderling VB, Hoeks J, Hesselink MKC, Phielix E, Houtkooper RH, Schrauwen P (2021) Sitting less elicits metabolic responses similar to exercise and enhances insulin sensitivity in postmenopausal women. Diabetologia 64:2817-28.HumanSkeletal muscleObesity
Cardinale 2021 J Appl Physiol (1985)2021Cardinale DA, Gejl KD, Petersen KG, Nielsen J, Ørtenblad N, Larsen FJ (2021) Short-term intensified training temporarily impairs mitochondrial respiratory capacity in elite endurance athletes. J Appl Physiol (1985) 131:388-400.HumanSkeletal muscle
Scheffer 2021 Brain Commun2021Scheffer DDL, Freitas FC, Aguiar AS Jr, Ward C, Guglielmo LGA, Prediger RD, Cronin SJF, Walz R, Andrews NA, Latini A (2021) Impaired dopamine metabolism is linked to fatigability in mice and fatigue in Parkinson's disease patients. Brain Commun 3:fcab116.RatSkeletal muscleParkinson's
Alves 2021 Eur J Nutr2021Alves BL, Araújo TDR, Guimarães DSPSF, Zoppi CC, Figueiredo MS, Carneiro EM (2021) Amino acid restriction alters survival mechanisms in pancreatic beta cells: possible role of the PI3K/Akt pathway. Eur J Nutr 60:3947-57.RatIslet cell;pancreas;thymus
Apostolopoulou 2021 Sci Adv2021Apostolopoulou M, Mastrototaro L, Hartwig S, Pesta D, Straßburger K, de Filippo E, Jelenik T, Karusheva Y, Gancheva S, Markgraf D, Herder C, Nair KS, Reichert AS, Lehr S, Müssig K, Al-Hasani H, Szendroedi J, Roden M (2021) Metabolic responsiveness to training depends on insulin sensitivity and protein content of exosomes in insulin-resistant males. https://doi.org/10.1126/sciadv.abi9551HumanSkeletal muscleDiabetes
Gomez-Valades 2021 Cell Metab2021Gómez-Valadés AG, Pozo M, Varela L, Boudjadja MB, Ramírez S, Chivite I, Eyre E, Haddad-Tóvolli R, Obri A, Milà-Guasch M, Altirriba J, Schneeberger M, Imbernón M, Garcia-Rendueles AR, Gama-Perez P, Rojo-Ruiz J, Rácz B, Alonso MT, Gomis R, Zorzano A, D'Agostino G, Alvarez CV, Nogueiras R, Garcia-Roves PM, Horvath TL, Claret M (2021) Mitochondrial cristae-remodeling protein OPA1 in POMC neurons couples Ca2+ homeostasis with adipose tissue lipolysis . Cell Metab 33:1820-35.e9.MouseNervous system
Hoene 2021 Mol Metab2021Hoene M, Kappler L, Kollipara L, Hu C, Irmler M, Bleher D, Hoffmann C, Beckers J, Hrabě de Angelis M, Häring HU, Birkenfeld AL, Peter A, Sickmann A, Xu G, Lehmann R, Weigert C (2021) Exercise prevents fatty liver by modifying the compensatory response of mitochondrial metabolism to excess substrate availability. Mol Metab 54:101359.MouseLiver
Szczerbinski 2021 Cells2021Szczerbinski L, Taylor MA, Puchta U, Konopka P, Paszko A, Citko A, Szczerbinski K, Goscik J, Gorska M, Larsen S, Kretowski A (2021) The response of mitochondrial respiration and quantity in skeletal muscle and adipose tissue to exercise in humans with prediabetes. Cells 10:3013.HumanSkeletal muscle
Fat		Diabetes
Dall 2021 J Biol Chem2021Dall M, Hassing AS, Niu L, Nielsen TS, Ingerslev LR, Sulek K, Trammell SAJ, Gillum MP, Barrès R, Larsen S, Poulsen SS, Mann M, Ørskov C, Treebak JT (2021) Hepatocyte-specific perturbation of NAD+ biosynthetic pathways in mice induces reversible nonalcoholic steatohepatitis-like phenotypes. J Biol Chem 297:101388.MouseLiverOther
Theall 2021 Physiol Rep2021Theall B, Stampley J, Cho E, Granger J, Johannsen NM, Irving BA, Spielmann G (2021) Impact of acute exercise on peripheral blood mononuclear cells nutrient sensing and mitochondrial oxidative capacity in healthy young adults. Physiol Rep 9:e15147.HumanBlood cells
Zanou 2021 Nat Commun2021Zanou N, Dridi H, Reiken S, Imamura de Lima T, Donnelly C, De Marchi U, Ferrini M, Vidal J, Sittenfeld L, Feige JN, Garcia-Roves PM, Lopez-Mejia IC, Marks AR, Auwerx J, Kayser B, Place N (2021) Acute RyR1 Ca2+ leak enhances NADH-linked mitochondrial respiratory capacity. Nat Commun 12:7219.MouseSkeletal muscle
Sarabhai 2021 Diabetologia2021Sarabhai T, Koliaki C, Mastrototaro L, Kahl S, Pesta D, Apostolopoulou M, Wolkersdorfer M, Bönner AC, Bobrov P, Markgraf DF, Herder C, Roden M (2021) Dietary palmitate and oleate differently modulate insulin sensitivity in human skeletal muscle. Diabetologia 65:301-14.HumanSkeletal muscleDiabetes
Davis 2021 Comparative Exercise Physiology2021Davis Michael, Barrett Montana, Popken Andrea (2021) Effect of hyperthermia and acidosis on equine skeletal muscle mitochondrial oxygen consumption. Comparative Exercise Physiology 17:171-179.HorseSkeletal muscleTemperature
Pesta 2021 Front Endocrinol (Lausanne)2021Pesta D, Jelenik T, Zaharia OP, Bobrov P, Görgens S, Bódis K, Karusheva Y, Krako Jakovljevic N, Lalic NM, Markgraf DF, Burkart V, Müssig K, Knebel B, Kotzka J, Eckel J, Strassburger K, Szendroedi J, Roden M (2021) NDUFB6 polymorphism is associated with physical activity-mediated metabolic changes in type 2 diabetes. https://doi.org/10.3389/fendo.2021.693683MouseSkeletal muscleDiabetes
Newsom 2021 Med Sci Sports Exerc2021Newsom SA, Stierwalt HD, Ehrlicher SE, Robinson MM (2021) Substrate-specific respiration of isolated skeletal muscle mitochondria after 1 h of moderate cycling in sedentary adults. https://doi.org/10.1249/mss.0000000000002615HumanSkeletal muscle
Krako Jakovljevic 2021 Int J Mol Sci2021Krako Jakovljevic N, Pavlovic K, Jotic A, Lalic K, Stoiljkovic M, Lukic L, Milicic T, Macesic M, Stanarcic Gajovic J, Lalic NM (2021) Targeting mitochondria in diabetes. Int J Mol Sci 22:6642.HumanSkeletal muscle
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Yoshino 2021 Science2021Yoshino M, Yoshino J, Kayser BD, Patti GJ, Franczyk MP, Mills KF, Sindelar M, Pietka T, Patterson BW, Imai SI, Klein S (2021) Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women. Science 372:1224-29. https://doi.org/10.1126/science.abe9985HumanSkeletal muscleDiabetes
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Stankova 2021 Int J Mol Sci2021Staňková P, Kučera O, Peterová E, Elkalaf M, Rychtrmoc D, Melek J, Podhola M, Zubáňová V, Červinková Z (2021) Western diet decreases the liver mitochondrial oxidative flux of succinate: insight from a murine NAFLD model. https://doi.org/10.3390/ijms22136908MouseLiverOxidative stress;RONSObesity
Hamm 2021 Mol Ther Methods Clin Dev2021Hamm SE, Fathalikhani DD, Bukovec KE, Addington AK, Zhang H, Perry JB, McMillan RP, Lawlor MW, Prom MJ, Vanden Avond MA, Kumar SN, Coleman KE, Dupont JB, Mack DL, Brown DA, Morris CA, Gonzalez JP, Grange RW (2023) Voluntary wheel running complements microdystrophin gene therapy to improve muscle function in mdx mice. https://doi.org/10.1016/j.omtm.2021.02.024MouseSkeletal muscleOther
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Mazzoli 2021 Antioxidants (Basel)2021Mazzoli A, Spagnuolo MS, Nazzaro M, Gatto C, Iossa S, Cigliano L (2021) Fructose removal from the diet reverses inflammation, mitochondrial dysfunction, and oxidative stress in hippocampus. Antioxidants (Basel) 10:487.RatNervous system
Hoppel 2021 Front Physiol2021Hoppel F, Calabria E, Pesta DH, Kantner-Rumplmair W, Gnaiger E, Burtscher M (2021) Effects of ultramarathon running on mitochondrial function of platelets and oxidative stress parameters: a pilot study. https://doi.org/10.3389/fphys.2021.632664HumanPlateletOxidative stress;RONS
Cormier 2021 Insect Biochem Mol Biol2021Cormier RJ, Strang R, Menail H, Touaibia M, Pichaud N (2021) Systemic and mitochondrial effects of metabolic inflexibility induced by high fat diet in Drosophila melanogaster. Insect Biochem Mol Biol 133:103556.DrosophilaObesity
Scalzo 2021 J Physiol2021Scalzo RL, Schauer IE, Rafferty D, Knaub LA, Kvaratskhelia N, Johnson TK, Pott GB, Abushamat LA, Whipple MO, Huebschmann AG, Cree-Green M, Reusch JEB, Regensteiner JG (2021) Single-leg exercise training augments in vivo skeletal muscle oxidative flux and vascular content and function in adults with type 2 diabetes. J Physiol 600:963-78.HumanSkeletal muscleDiabetes
Moon 2021 J Lipid Res2021Moon SH, Dilthey BG, Liu X, Guan S, Sims HF, Gross RW (2021) High-Fat diet activates liver iPLA2γ generating eicosanoids that mediate metabolic stress. J Lipid Res 62:100052.MouseLiverObesity
Braga 2021 Sci Rep2021Braga RR, Crisol BM, Brícola RS, Sant'ana MR, Nakandakari SCBR, Costa SO, Prada PO, da Silva ASR, Moura LP, Pauli JR, Cintra DE, Ropelle ER (2021) Exercise alters the mitochondrial proteostasis and induces the mitonuclear imbalance and UPRmt in the hypothalamus of mice. Sci Rep 11:3813.MouseNervous system
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Mendham 2021 Diabetologia2021Mendham AE, Goedecke JH, Zeng Y, Larsen S, George C, Hauksson J, Fortuin-de Smidt MC, Chibalin AV, Olsson T, Chorell E (2021) Exercise training improves mitochondrial respiration and is associated with an altered intramuscular phospholipid signature in women with obesity. Diabetologia 64:1642-59.HumanSkeletal muscleObesity
Flensted-Jensen 2021 Free Radic Biol Med2021Flensted-Jensen M, Gram M, Dela F, Helge JW, Larsen S (2021) Six weeks of high intensity cycle training reduces H2O2 emission and increases antioxidant protein levels in obese adults with risk factors for type 2 diabetes. Free Radic Biol Med 173:1-6.HumanSkeletal muscleObesity
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Avin 2021 Sci Rep2021Avin KG, Hughes MC, Chen NX, Srinivasan S, O'Neill KD, Evan AP, Bacallao RL, Schulte ML, Moorthi RN, Gisch DL, Perry CGR, Moe SM, O'Connell TM (2021) Skeletal muscle metabolic responses to physical activity are muscle type specific in a rat model of chronic kidney disease. Sci Rep 11:9788.RatSkeletal muscleOther
MacCannell 2021 Int J Obes (Lond)2021MacCannell ADV, Futers TS, Whitehead A, Moran A, Witte KK, Roberts LD (2021) Sexual dimorphism in adipose tissue mitochondrial function and metabolic flexibility in obesity. Int J Obes (Lond) 45:1773-81.MouseFatObesity
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Trinity 2021 J Appl Physiol2021Trinity JD, Craig JC, Fermoyle CC, McKenzie AI, Lewis MT, Park SH, Rondina MT, Richardson RS (2021) Impact of presymptomatic COVID-19 on vascular and skeletal muscle function: a case study. J Appl Physiol (1985) 130:1961-70.HumanSkeletal muscleInfectious
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