Free Radic Biol Med

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Journal title and website Free Radical Biology and Medicine

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Wang 2019 Free Radic Biol MedPMID: 30611867Wang SQ, Yang XY, Cui SX, Gao ZH, Qu XJ (2019) Heterozygous knockout insulin-like growth factor-1 receptor (IGF-1R) regulates mitochondrial functions and prevents colitis and colorectal cancer. Free Radic Biol Med 134:87-98.2019
Antonucci 2019 Free Radic Biol MedPMID: 30731114 Open accessAntonucci S, Mulvey JF, Burger N, Di Sante M, Hall AR, Hinchy EC, Caldwell ST, Gruszczyk AV, Deshwal S, Hartley RC, Kaludercic N, Murphy MP, Di Lisa F, Krieg T (2019) Selective mitochondrial superoxide generation in vivo is cardioprotective through hormesis. Free Radic Biol Med 134:678-687.2019
Rojas-Morales 2019 Free Radic Biol MedPMID: 30818054Rojas-Morales P, León-Contreras JC, Aparicio-Trejo OE, Reyes- Ocampo JG, Medina-Campos ON, Jiménez-Osorio AS, González-Reyes S, Marquina- Castillo B, Hernández-Pando R, Barrera-Oviedo D, Sánchez-Lozada LG, Pedraza-Chaverri J, Tapia E (2019) Fasting reduces oxidative stress, mitochondrial dysfunction and fibrosis induced by renal ischemia-reperfusion injury. Free Radic Biol Med 135:60-67.2019
Pileggi 2018 Free Radic Biol MedPMID: 29909291 »O2k-briefPileggi CA, Hedges CP, D'Souza RF, Durainayagam BR, Markworth JF, Hickey AJR, Mitchell CJ, Cameron-Smith D (2018) Exercise recovery increases skeletal muscle H2O2 emission and mitochondrial respiratory capacity following two-weeks of limb immobilization. Free Radic Biol Med 124:241-8.2018
Christen 2018 Free Radic Biol MedPMID: 29294390Christen F, Desrosiers V, Dupont-Cyr BA, Vandenberg GW, Le François NR, Tardif JC, Dufresne F, Lamarre SG, Blier PU (2018) Thermal tolerance and thermal sensitivity of heart mitochondria: Mitochondrial integrity and ROS production. Free Radic Biol Med 116:11-8.2018
Aparicio-Trejo 2018 Free Radic Biol MedPMID: 30439416 Open AcessAparicio-Trejo OE, Reyes-Fermín LM, Briones-Herrera A, Tapia E, León-Contreras JC, Hernández-Pando R, Sánchez-Lozada LG, Pedraza-Chaverri J (2018) Protective effects of N-acetyl-cysteine in mitochondria bioenergetics, oxidative stress, dynamics and S-glutathionylation alterations in acute kidney damage induced by folic acid. Free Radic Biol Med 130:379-96.2018
Houghton 2018 Free Radic Biol MedPMID: 30266680Houghton MJ, Kerimi A, Tumova S, Boyle JP, Williamson G (2018) Quercetin preserves redox status and stimulates mitochondrial function in metabolically-stressed HepG2 cells. Free Radic Biol Med 129:296-309.2018
Gao 2018 Free Radic Biol MedPMID: 29935261Gao JL, Zhao J, Zhu HB, Peng X, Zhu JX, Ma MH, Fu Y, Hu N, Tai Y, Xuan XC, Dong DL (2018) Characterizations of mitochondrial uncoupling induced by chemical mitochondrial uncouplers in cardiomyocytes. Free Radic Biol Med 124:288-98.2018
Li 2018 Free Radic Biol MedPMID: 29559323Li H, Tang Z, Chu P, Song Y, Yang Y, Sun B, Niu M, Qaed E, Shopit A, Han G, Ma X, Peng J, Hu M, Tang Z (2018) Neuroprotective effect of phosphocreatine on oxidative stress and mitochondrial dysfunction induced apoptosis in vitro and in vivo: Involvement of dual PI3K/Akt and Nrf2/HO-1 pathways. Free Radic Biol Med 120:228-38.2018
Campbell 2018 Free Radic Biol MedPMID: 30597195Campbell MD, Duan J, Samuelson AT, Gaffrey MJ, Wang L, Bammler TK, Moore RJ, White CC, Kavanagh TJ, Voss JG, Szeto HH, Rabinovitch PS, Qian WJ, Marcinek DJ (2018) Improving mitochondrial function with SS-31 reverses age-related redox stress and improves exercise tolerance in aged mice. Free Radic Biol Med 134:268-81.2018
Zhou 2018 Free Radic Biol MedPMID: 30223019Zhou L, Yi Y, Yuan Q, Zhang J, Li Y, Wang P, Xu M, Xie S (2018) VAOS, a novel vanadyl complexes of alginate saccharides, inducing apoptosis via activation of AKT-dependent ROS production in NSCLC. Free Radic Biol Med 129:177-85.2018
Kim 2018 Free Radic Biol MedPMID: 30037775 Open AccessKim M, Stepanova A, Niatsetskaya Z, Sosunov S, Arndt S, Murphy MP, Galkin A, Ten VS (2018) Attenuation of oxidative damage by targeting mitochondrial complex I in neonatal hypoxic-ischemic brain injury. Free Radic Biol Med 124:517-24.2018
Rodrigues 2018 Free Radic Biol MedPMID: 29655867Rodrigues NR, Macedo GE, Martins IK, Gomes KK, de Carvalho NR, Posser T, Franco JL (2018) Short-term sleep deprivation with exposure to nocturnal light alters mitochondrial bioenergetics in Drosophila. Free Radic Biol Med 120:395-406.2018
Silva 2018 Free Radic Biol MedPMID: 30118829Silva RP, Carvalho LAC, Patricio ES, Bonifacio JPP, Chaves-Filho AB, Miyamoto S, Meotti FC (2018) Identification of urate hydroperoxide in neutrophils: A novel pro-oxidant generated in inflammatory conditions. Free Radic Biol Med 126:177-86.2018
Orrico 2018 Free Radic Biol MedPMID: 29753074»O2k-briefOrrico F, Möller MN, Cassina A, Denicola A, Thomson L (2018) Kinetic and stoichiometric constraints determine the pathway of Catalase; Glutathione peroxidase; Hydrogen peroxide; Peroxiredoxin; Reaction kinetic; Reaction rate; Red blood cells consumption by red blood cells. Free Radic Biol Med 121:231-9.2018
Cejvanovic 2018 Free Radic Biol MedPMID: 29157668Cejvanovic V, Kjær LK, Bergholdt HKM, Torp-Pedersen A, Henriksen T, Weimann A, Ellervik C, Poulsen HE (2018) Iron induced RNA-oxidation in the general population and in mouse tissue. Free Radic Biol Med 115:127-35.2018
Kamunde 2018 Free Radic Biol MedPMID: 29802890Kamunde C, Sharaf M, MacDonald N (2018) H2O2 metabolism in liver and heart mitochondria: Low emitting-high scavenging and high emitting-low scavenging systems. Free Radic Biol Med 124:135-48.2018
De Paula Martins 2018 Free Radic Biol MedPMID: 29198726de Paula Martins R, Ghisoni K, Lim CK, Aguiar AS Jr, Guillemin GJ, Latini A (2018) Neopterin preconditioning prevents inflammasome activation in mammalian astrocytes. Free Radic Biol Med 115:371-82.2018
Bombaca 2018 Free Radic Biol MedPMID: 30445126 Open AccessBombaça ACS, Viana PG, Santos ACC, Silva TL, Rodrigues ABM, Guimarães ACR, Goulart MOF, Da Silva Júnior EN, Menna-Barreto RFS (2018) Mitochondrial disfunction and ROS production are essential for anti-Trypanosoma cruzi activity of β-lapachone-derived naphthoimidazoles. Free Radic Biol Med 130:408-18.2018
Pfeiffer 2017 Free Radic Biol MedPMID: 28807815Pfeiffer A, Schneider J, Bueno D, Dolga A, Voss TD, Lewerenz J, Wüllner V, Methner A (2017) Bcl-xL knockout attenuates mitochondrial respiration and causes oxidative stress that is compensated by pentose phosphate pathway activity. Free Radic Biol Med 112:350-9.2017
Nogueira 2017 Free Radic Biol MedPMID: 28363600Nogueira NP, Saraiva FMS, Oliveira MP, Mendonca APM, Inacio JDF, Almeida-Amaral EE, Menna-Barreto RF, Laranja GAT, Lopes Torres EJ, Oliveira MF, Paes MC (2017) Heme modulates Trypanosoma cruzi bioenergetics inducing mitochondrial ROS production. Free Radic Biol Med 108:183-91.2017
Yu 2017 Free Radic Biol MedPMID: 28826719Yu Y, Wang L, Delguste F, Durand A, Guilbaud A, Rousselin C, Schmidt AM, Tessier F, Boulanger E, Neviere R (2017) Advanced glycation end products receptor RAGE controls myocardial dysfunction and oxidative stress in high-fat fed mice by sustaining mitochondrial dynamics and autophagy-lysosome pathway. Free Radic Biol Med 112:397-410.2017
Dixit 2017 Free Radic Biol MedPMID: 28863942Dixit S, Fessel JP, Harrison FE (2017) Mitochondrial dysfunction in the APP/PSEN1 mouse model of Alzheimer's disease and a novel protective role for ascorbate. Free Radic Biol Med 112:515-23.2017
Alves 2017 Free Radic Biol MedPMID: 28629835Alves de Souza CE, Alves de Souza HM, Stipp MC, Corso CR, Galindo CM, Cardoso CR, Dittrich RL, de Souza Ramos EA, Klassen G, Carlos RM, Correia Cadena SMS, Acco A (2017) Ruthenium complex exerts antineoplastic effects that are mediated by oxidative stress without inducing toxicity in Walker-256 tumor-bearing rats. Free Radic Biol Med 110:228-39.2017
Bombaca 2017 Free Radic Biol MedPMID: 28993269Bombaça ACS, Dias FA, Ennes-Vidal V, Garcia-Gomes ADS, Sorgine MHF, d'Avila-Levy CM, Menna-Barreto RFS (2017) Hydrogen peroxide resistance in Strigomonas culicis: Effects on mitochondrial functionality and Aedes aegypti interaction. Free Radic Biol Med 113:255-66.2017
Menezes-Filho 2017 Free Radic Biol MedPMID: 28642067Menezes-Filho SL, Amigo I, Prado FM, Ferreira NC, Koike MK, Pinto IFD, Miyamoto S, Montero EFS, Medeiros MHG, Kowaltowski AJ (2017) Caloric restriction protects livers from ischemia/reperfusion damage by preventing Ca2+-induced mitochondrial permeability transition. Free Radic Biol Med 110:219-27.2017
Xu 2017 Free Radic Biol MedPMID: 28219781Xu J, Bian X, Liu Y, Hong L, Teng T, Sun Y, Xu Z (2017) Adenosine A2 receptor activation ameliorates mitochondrial oxidative stress upon reperfusion through the posttranslational modification of NDUFV2 subunit of complex I in the heart. Free Radic Biol Med 106:208-18.2017
Blecha 2017 Free Radic Biol MedPMID: 28774815Blecha J, Novais SM, Rohlenova K, Novotna E, Lettlova S, Schmitt S, Zischka H, Neuzil J, Rohlena J (2017) Antioxidant defense in quiescent cells determines selectivity of electron transport chain inhibition-induced cell death. Free Radic Biol Med 112:253-66.2017
Sengupta 2016 Free Radic Biol MedPMID: 26855417Sengupta S, Yang G, O'Donnell JC, Hinson MD, McCormack SE, Falk MJ, La P, Robinson MB, Williams ML, Yohannes MT, Polyak E, Nakamaru-Ogiso E, Dennery PA (2016) The circadian gene Rev-erbα improves cellular bioenergetics and provides preconditioning for protection against oxidative stress. Free Radic Biol Med 93:177-89.2016
Peleli 2016 Free Radic Biol MedPMID: 27609225Peleli M, Zollbrecht C, Montenegro MF, Hezel M, Zhong J, Persson EG, Holmdahl R, Weitzberg E, Lundberg JO, Carlström M (2016) Enhanced XOR activity in eNOS-deficient mice: Effects on the nitrate-nitrite-NO pathway and ROS homeostasis. Free Radic Biol Med 99:472-84.2016
Munro 2016 Free Radic Biol MedPMID: 27101737Munro D, Banh S, Sotiri E, Tamanna N, Treberg JR (2016) The thioredoxin and glutathione-dependent H2O2 consumption pathways in muscle mitochondria: Involvement in H2O2 metabolism and consequence to H2O2 efflux assays. Free Radic Biol Med 96:334-46.2016
Roy 2016 Free Radic Biol MedPMID: 27932075Roy J, Fauconnier J, Oger C, Farah C, Angebault-Prouteau C, Thireau J, Bideaux P, Scheuermann V, Bultel-Poncé V, Demion M, Galano JM, Durand T, Lee JC, Le Guennec JY (2016) Non-enzymatic oxidized metabolite of DHA, 4(RS)-4-F4t-neuroprostane protects the heart against reperfusion injury. Free Radic Biol Med 102:229-39.2016
Torelli 2015 Free Radic Biol MedPMID:25578655Torelli NQ, Ferreira-Júnior JR, Kowaltowski AJ, da Cunha FM (2015) RTG1- and RTG2-dependent retrograde signaling controls mitochondrial activity and stress resistance in Saccharomyces cerevisiae. Free Radic Biol Med 81C:30-7.2015
Singh 2015 Free Radic Biol MedPMID: 26025579Singh P, Sharma R, McElhanon K, Allen CD, Megyesi JK, Beneš H, Singh SP (2015) Sulforaphane protects the heart from doxorubicin-induced toxicity. Free Radic Biol Med 86:90-101.2015
Miwa 2015 Free Radic Biol MedPMID: 26577176 Open AccessMiwa S, Treumann A, Bell A, Vistoli G, Nelson G, Hay S, von Zglinicki T (2015) Carboxylesterase converts Amplex red to resorufin: Implications for mitochondrial H2O2 release assays.. Free Radic Biol Med 90:173-83.2015
Adesina 2015 Free Radic Biol MedOpen AccessAdesina SE, Kang BY, Bijli KM, Ma J, Cheng J, Murphy TC, Michael Hart C, Sutliff RL (2015) Targeting mitochondrial reactive oxygen species to modulate hypoxia-induced pulmonary hypertension. Free Radic Biol Med 87:36-47.2015
Dungel 2015 Free Radic Biol MedPMID: 26415027Dungel P, Perlinger M, Weidinger A, Redl H, Kozlov AV (2015) The cytoprotective effect of nitrite is based on the formation of dinitrosyl iron complexes. Free Radic Biol Med 89:300-10.2015
Hermes-Lima 2015PubMedHermes-Lima M, Moreira DC, Rivera-Ingraham GA, Giraud-Billoud M, Genaro-Mattos TC, Campos ÉG (2015) Preparation for oxidative stress under hypoxia and metabolic depression: Revisiting the proposal two decades later. Free Radic Biol Med 2015 Dec;89:1122-43.2015
Miquel 2014 Free Radic Biol MedPMID: 24582549Miquel E, Cassina A, Martínez-Palma L, Souza JM, Bolatto C, Rodríguez-Bottero S, Logan A, Smith RA, Murphy MP, Barbeito L, Radi R, Cassina P (2014) Neuroprotective effects of the mitochondria-targeted antioxidant MitoQ in a model of inherited amyotrophic lateral sclerosis. Free Radic Biol Med 70:204-13.2014
Hernansanz-Agustín 2014 Free Radic Biol MedPMID: 24637263Hernansanz-Agustín P, Izquierdo-Álvarez A, Sánchez-Gómez FJ, Ramos E, Villa-Piña T, Lamas S, Bogdanova A, Martínez-Ruiz A (2014) Acute hypoxia produces a superoxide burst in cells. Free Radic Biol Med 71:146-56.2014
Ambrosio 2014 Free Radic Biol MedPMID: 24960579Ambrosio F, Brown E, Stolz D, Ferrari R, Goodpaster BH, Deasy B, Distefano G, Roperti A, Cheikhi A, Garciafigueroa Y, Barchowsky A (2014) Arsenic induces sustained impairment of skeletal muscle and muscle progenitor cell ultrastructure and bioenergetics. Free Radic Biol Med 74C:64-73.2014
Tretter 2014 Free Radic Biol MedPMID: 25277417 Open AccessTretter L, Horvath G, Hölgyesi A, Essek F, Adam-Vizi V (2014) Enhanced hydrogen peroxide generation accompanies the beneficial bioenergetic effects of methylene blue in isolated brain mitochondria. Free Radic Biol Med 77:317-30.2014
Bleier 2014 Free Radic Biol MedPMID: 25451644Bleier L, Wittig I, Heide H, Steger M, Brandt U, Droese S4 (2014) Generator-specific targets of mitochondrial reactive oxygen species. Free Radic Biol Med 78:1-10.2014
Li 2013 Free Radic Biol MedPMID:23643721 Open AccessLi H, Kumar Sharma L, Li Y, Hu P, Idowu A, Liu D, Lu J, Bai Y (2013) Comparative bioenergetic study of neuronal and muscle mitochondria during aging. Free Radic Biol Med 63:30-40.2013
Gilliam 2013 Free Radic Biol MedPMID: 24017970 Open AccessGilliam LA, Fisher-Wellman KH, Lin CT, Maples JM, Cathey BL, Neufer PD (2013) The anticancer agent doxorubicin disrupts mitochondrial energy metabolism and redox balance in skeletal muscle. Free Radic Biol Med 65:988-96.2013
Piccoli 2012 Free Radic Biol MedPMID: 22240155Piccoli C, D'Aprile A, Scrima R, Ambrosi L, Zefferino R, Capitanio N (2012) Subcytotoxic mercury chloride inhibits gap junction intercellular communication by a redox- and phosphorylation-mediated mechanism. Free Radic Biol Med 52: 916-927.2012
Kwak 2012 Free Radic Biol MedPMID: 22080086Kwak HB, Thalacker-Mercer A, Anderson EJ, Lin CT, Kane DA, Lee NS, Cortright RN, Bamman MM, Neufer PD (2012) Simvastatin impairs ADP-stimulated respiration and increases mitochondrial oxidative stress in primary human skeletal myotubes. Free Radic Biol Med 52:198-207.2012
Tretter 2012 Free Radic Biol MedPMID: 23022874Tretter L, Adam-Vizi V (2012) High Ca2+ load promotes hydrogen peroxide generation via activation of α-glycerophosphate dehydrogenase in brain mitochondria. Free Radic Biol Med 53:2119-30.2012
Zhao 2011 Free Radic Biol MedPMID: 22576106Zhao B, Ranguelova K, Jiang J, Mason RP (2011) Studies on the photosensitized reduction of resorufin and implications for the detection of oxidative stress with Amplex Red. Free Radic Biol Med 51:153-92011
Hernandez-Mijares 2011 Free Radic Biol MedPMID: 21262346Hernandez-Mijares A, Rocha M, Apostolova N, Borras C, Jover A, Bañuls C, Sola E, Victor VM (2011) Mitochondrial complex I impairment in leukocytes from type 2 diabetic patients. Free Radic Biol Med 50:1215-21.2011
Bullon 2011 Free Radic Biol MedPMID: 21354301Bullon P, Cordero MD, Quiles JL, Morillo JM, del Carmen Ramirez-Tortosa M, Battino M (2011) Mitochondrial dysfunction promoted by Porphyromonas gingivalis lipopolysaccharide as a possible link between cardiovascular disease and periodontitis. Free Radic Biol Med 50:1336-43.2011
Sangle 2010 Free Radic Biol MedPMID: 20036735Sangle GV, Chowdhury SK, Xie X, Stelmack GL, Halayko AJ, Shen GX (2010) Impairment of mitochondrial respiratory chain activity in aortic endothelial cells induced by glycated low-density lipoprotein. Free Radic Biol Med 48:781-90.2010
Kane 2010 Free Radic Biol MedPMID: 20600832 Open AccessKane DA, Anderson EJ, Price III JW, Woodlief TL, Lin C-T, Bikman BT, Cortright RN, Neufer PD (2010) Metformin selectively attenuates mitochondrial H2O2 emission without affecting respiratory capacity in skeletal muscle of obese rats. Free Radic Biol Med 49:1082–7.2010
Zielonka 2010 Free Radic Biol MedPMC3587154 Open AccessZielonka J, KalyanaramanB (2010) Hydroethidine- and Mito-SOX-derived red fluorescence is not a reliable indicator of intracellular superoxide formation: Another inconvenient truth. Free Radic Biol Med 48:983–1001..2010
Mishin 2010 Free Radical Biol MedPMID: 20188819 Open accessMishin V, Gray JP, Heck DE, Laskin DL, Laskin JD (2010) Application of Amplex red/horseradish peroxidase assay to measure hydrogen peroxide production by recombinant microsomal enzymes. Free Radic Biol Med 48:1485-91.2010
Tahara 2009 Free Radic Biol MedPMID: 19245829Tahara EB, Navarete FD, Kowaltowski AJ (2009) Tissue-, substrate-, and site-specific characteristics of mitochondrial reactive oxygen species generation. Free Radic Biol Med 46:1283-97.2009
Menna-Barreto 2009 Free Radic Biol MedPMID: 19501647Menna-Barreto RF, Goncalves RL, Costa EM, Silva RS, Pinto AV, Oliveira MF, de Castro SL (2009) The effects on Trypanosoma cruzi of novel synthetic naphthoquinones are mediated by mitochondrial dysfunction. Free Radic Biol Med 47:644-53.2009
Schoenfeld 2009 Free Radic Biol MedPMID: 19442717Schönfeld P, Dymkowska D, Wojtczak L (2009) Acyl-CoA-induced generation of reactive oxygen species in mitochondrial preparations is due to the presence of peroxisomes. Free Radic Biol Med 47:503-9.2009
Samper 2009 Free Radic Biol MedPMID: 19038329 Open AccessSamper E, Morgado L, Estrada JC, Bernad A, Hubbard A, Cadenas S, Melov S (2009) Increase in mitochondrial biogenesis, oxidative stress, and glycolysis in murine lymphomas. Free Radic Biol Med 46:387-96.2009
Hansson 2008 Free Radic Biol MedPMID: 18466779Hansson Magnus J, Månsson R, Morota S, Uchino H, Kallur T, Sumi T, Ishii N, Shimazu M, Keep MF, Jegorov A, Elmér E (2008) Calcium-induced generation of reactive oxygen species in brain mitochondria is mediated by permeability transition. Free Radic Biol Med 45:284-94.2008
Boada 2004 Free Radical Biol MedPMID: 15182857Boada J, Cuesta E, Perales JC, Roig T, Bermudez J (2004) Glutathione content and adaptation to endogenously induced energy depletion in Mv1Lu cells. Free Radic Biol Med 15:1555-65.2004
Borras 2003 Free Radic Biol MedPMID: 12614843Borrás C, Sastre J, García-Sala D, Lloret A, Pallardó FV, Viña J (2003) Mitochondria from females exhibit higher antioxidant gene expression and lower oxidative damage than males. Free Radic Biol Med 34:546-52..2003
Perry 2002 Free Radic Biol MedPMID: 12446204Perry G, Nunomura A, Hirai K, Zhu X, Pérez M, Avila J, Castellani RJ, Atwood CS, Aliev G, Sayre LM, Takeda A, Smith MA (2002) Is oxidative damage the fundamental pathogenic mechanism of Alzheimer's and other neurodegenerative diseases? Free Radic Biol Med 33:1475-9.2002
Schafer 2001 Free Radic Biol MedPMID: 11368918Schafer FQ, Buettner GR (2001) Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple. Free Radic Biol Med 30(11):1191-212.2001
Du 1999 Free Radic Biol MedPMID: 10490280Du G, Willet K, Mouithys-Mickalad A, Sluse-Goffart CM, Droy-Lefaix M-T, Sluse FE (1999) EGb 761 protects liver mitochondria against injury induced by in vitro anoxia/reoxygenation. Free Radic Biol Med 27:596-604.1999
Du 1998 Free Radic Biol MedPMID: 9870560Du G, Mouithys-Mickalad A, Sluse FE (1998) Generation of superoxide anion by mitochondria and impairment of their functions during anoxia and reoxygenation. Free Radic Biol Med 25:1066-74.1998