Pecina Petr

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COST Action CA15203 (2016-2021): MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping

Pecina Petr

MitoPedia topics: EAGLE

COST: Member

COST WG4: WG4

Name	Pecina Petr, Dr.
Institution	Laboratory of Bioenergetics, Institute of Physiology, Academy of Sciences of the Czech Republic, CZ
Address	Videnska 1083, 14220
City	Prague
State/Province
Country	Czech Republic
Email	petr.pecina@fgu.cas.cz
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O2k-Network Lab	CZ Prague Houstek J

Participated at

Labels: Field of research: Basic

Publications

	Published	Reference
Markovic 2022 Biomedicines	2022	Marković A, Tauchmannová K, Šimáková M, Mlejnek P, Kaplanová V, Pecina P, Pecinová A, Papoušek F, Liška F, Šilhavý J, Mikešová J, Neckář J, Houštěk J, Pravenec M, Mráček T (2022) Genetic complementation of ATP synthase deficiency due to dysfunction of TMEM70 assembly factor in rat. https://doi.org/10.3390/biomedicines10020276
Pajuelo-Reguera 2020 Cells	2020	Pajuelo Reguera David, Čunátová Kristýna, Vrbacký Marek, Pecinová Alena, Houštěk Josef, Mráček Tomáš, Pecina Petr (2020) Cytochrome c oxidase subunit 4 isoform exchange results in modulation of oxygen affinity. Cells 9:E443.
BEC 2020.1 doi10.26124bec2020-0001.v1	2020	Gnaiger E et al ― MitoEAGLE Task Group (2020) Mitochondrial physiology. Bioenerg Commun 2020.1. https://doi.org/10.26124/bec:2020-0001.v1
Pajuelo 2020 Cells	2020	Pajuelo Reguera D, Čunátová K, Vrbacký M, Pecinová A, Houštěk J, Mráček T, Pecina P (2020) Cytochrome c oxidase subunit 4 isoform exchange results in modulation of oxygen affinity. Cells 9:443.
Pecinova 2017 Oxid Med Cell Longev	2017	Pecinova A, Drahota Z, Kovalcikova J, Kovarova N, Pecina P, Alan L, Zima M, Houstek J, Mracek T (2017) Pleiotropic effects of biguanides on mitochondrial reactive oxygen species production. Oxid Med Cell Longev 7038603.
Hartmannova 2016 Hum Mol Genet	2016	Hartmannová H, Piherová L, Tauchmannová K, Kidd K, Acott PD, Crocker JF, Oussedik Y, Mallet M, Hodaňová K, Stránecký V, Přistoupilová A, Barešová V, Jedličková I, Živná M, Sovová J, Hůlková H, Robins V, Vrbacký M, Pecina P, Kaplanová V, Houštěk J, Mráček T, Thibeault Y, Bleyer AJ, Kmoch S (2016) Acadian variant of Fanconi syndrome is caused by mitochondrial respiratory chain complex I deficiency due to a non-coding mutation in complex I assembly factor NDUFAF6. Hum Mol Genet 25:4062-79.
Pecina 2014 Biochim Biophys Acta Clinical	2014	Pecina P, Houstkova H, Mracek T, Pecinova A, Nuskova H.Tesarova M, Hansikova H, Janota J, Zemanc J, Houstek J (2014) Noninvasive diagnostics of mitochondrial disorders in isolated lymphocytes with high resolution respirometry. Biochim Biophys Acta Clinical 2:62–71. https://doi.org/10.1016/j.bbacli.2014.09.003
Pecinova 2011 Mitochondrion	2011	Pecinova A, Drahota Z, Nuskova H, Pecina P, Houstek J (2011) Evaluation of basic mitochondrial functions using rat tissue homogenates. Mitochondrion 11:722-8.
Hervouet 2008 Carcinogenesis	2008	Hervouet E, Cízková A, Demont J, Vojtísková A, Pecina P, Franssen-van Hal NL, Keijer J, Simonnet H, Ivánek R, Kmoch S, Godinot C, Houstek J (2008) HIF and reactive oxygen species regulate oxidative phosphorylation in cancer. Carcinogenesis 29:1528-37.
Hervouet 2006 Biochem Biophys Res Commun	2006	Hervouet E, Pecina P, Demont J, Vojtíšková A, Simonnet H, Houštek J, Godinot C (2006) Inhibition of cytochrome c oxidase subunit 4 precursor processing by the hypoxia mimic cobalt chloride. Biochem Biophys Res Commun 344:1086-93.
Hervouet 2005 Carcinogenesis	2005	Hervouet E, Demont J, Pecina P, Vojtísková A, Houstek J, Simonnet H, Godinot C (2005) A new role for the von Hippel-Lindau tumor suppressor protein: Stimulation of mitochondrial oxidative phosphorylation complex biogenesis. Carcinogenesis 26:531-9.
Pecina 2004 Am J Physiol Cell Physiol	2004	Pecina P, Gnaiger E, Zeman J, Pronicka E, Houstek J (2004) Decreased affinity to oxygen of cytochrome c oxidase in Leigh syndrome caused by SURF1 mutations. Am J Physiol Cell Physiol 287:C1384-8.
Jesina 2004 Biochem J	2004	Jesina P, Tesarova M, Fornuskova D, Vojtiskova A, Pecina P, Kaplanova V, Hansikova H, Zeman J, Houstek J (2004) Diminished synthesis of subunit a (ATP6) and altered function of ATP synthase and cytochrome c oxidase due to the mtDNA 2 bp microdeletion of TA at positions 9205 and 9206. Biochem J 383:561-71.
Mayr 2004 Pediatr Res	2004	Mayr JA, Paul J, Pecina P, Kurnik P, Forster H, Fotschl U, Sperl W, Houstek J (2004) Reduced respiratory control with ADP and changed pattern of respiratory chain enzymes as a result of selective deficiency of the mitochondrial ATP synthase. Pediatr Res 55:988-94.
Pecina 2004 Physiol Res	2004	Pecina P, Houstkova H, Hansikova H, Zeman J, Houstek J (2004) Genetic defects of cytochrome c oxidase assembly. Physiol Res 53 Suppl 1:S213-23.
Pecina 2003 Biochim Biophys Acta	2003	Pecina P, Capkova M, Chowdhury SK, Drahota Z, Dubot A, Vojtiskova A, Hansikova H, Houstekova H, Zeman J, Godinot C, Houstek J (2003) Functional alteration of cytochrome c oxidase by SURF1 mutations in Leigh syndrome. Biochim Biophys Acta 1639:53-63.

Abstracts

	Published	Reference
Mracek 2017 MiP2017	2017	Knockout of DAPIT, an accessory subunit of mitochondrial ATP synthase, causes right ventricular hypertrophy and pulmonary hypertension.
Pecinova 2017 MiP2017	2017	Targeting tumor cell proliferation by inhibition of mitochondrial metabolic pathways.
Pecina 2017 MiP2017	2017	Mitochondrial ATP synthase disorders investigated by quantitative proteomics of CRISPR-Cas9 knockout cell lines.
Pajuelo-Reguera 2017 MiP2017	2017	COX4-1/COX4-2 cell knock-out/knock-in models for the study of cytochrome c oxidase regulation.
Efimova 2017 MiP2017	2017	Purification and subunit composition analysis in the models of mammalian ATP synthase deficiencies.
Cunatova 2017 MiP2017	2017	COX4-1/4-2 knock-out causes total cytochrome c oxidase deficiency and partial impairment of mitochondrial proteosynthesis.
Brazdova 2017 MiP2017	2017	Pleiotropic effects of biguanides on mitochondrial reactive oxygen species production.
Alan 2017 MiP2017	2017	Role of MLQ protein in the structure and function of mammalian F₁F_O ATP-synthase.
Kovarova 2015 Abstract MiP2015	2015	Tissue- and species-specific differences in cytochrome c oxidase assembly induced by SURF1 defects.
Nuskova 2015 Abstract MiP2015	2015	Insufficient energy provision or increased oxidative stress – what matters more in ATP synthase deficiencies?
Tauchmannova 2015 Abstract MiP2015	2015	Assembly of subunit F_o-a into mammalian ATP synthase.
Pecina 2015 Abstract MiP2015	2015	Pharmacological inhibition of fatty-acid oxidation synergistically enhances the effect of L-asparaginase in childhood ALL cells.
Mracek 2015 Abstract MiP2015	2015	Myocardial iron and mitochondrial function in failing and non-failing human heart: direct tissue analysis.
Nuskova 2015 Abstract MiPschool London 2015	2015	Insufficient energy provision or increased oxidative stress – what matters more in ATP synthase deficiencies?
Pecina 2014 Abstract MiP2014	2014	Manifestation of mitochondrial disorders of nuclear origin in lymphocytes.
Pecina 2013 Abstract MiP2013	2013	Pecina P, Houšťková H, Mráček T, Pecinová A, Nůsková H, Tesařová M, Hansíková H, Janota J, Zeman J, Houštěk J (2013) The use of lymphocytes for diagnostics of mitochondrial oxidative phosphorylation disorders. Mitochondr Physiol Network 18.08.
Nuskova 2011 Abstract IOC61	2011	Nuskova H, Pecina P, Kovarova N, Dell’Agnello C, Zeviani M, Houstek J (2011) Cytochrome c oxidase with decreased H+/e− ratio in SURF1 knockout mice. MiPNet16.01.