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From Bioblast
 YearReferenceCouplingPathwayPreparationOrganismTissue;cell
Macheiner 2016 Sci Rep2016Macheiner T, Fengler VH, Agreiter M, Eisenberg T, Madeo F, Kolb D, Huppertz B, Ackbar R, Sargsyan K (2016) Magnetomitotransfer: An efficient way for direct mitochondria transfer into cultured human cells. Sci Rep 6:35571.LEAK
ROUTINE
ET
ROXHumanFibroblast
Lung;gill
Cacabelos 2016 Neurobiol Dis2016Cacabelos D, Ayala V, Granado-Serrano AB, JovĂ© M, Torres P, Boada J, CabrĂ© R, RamĂ­rez-NĂșñez O, Gonzalo H, Soler-Cantero A, Serrano JC, Bellmunt MJ, Romero MP, Motilva MJ, Nonaka T, Hasegawa M, Ferrer I, Pamplona R, Portero-OtĂ­n M (2016) Interplay between TDP-43 and docosahexaenoic acid-related processes in amyotrophic lateral sclerosis. Neurobiol Dis 88:148-60.ROUTINEIntact cellsRatNervous system
Bynum 2016 Transfusion2016Bynum JA, Adam Meledeo M, Getz TM, Rodriguez AC, Aden JK, Cap AP, Pidcoke HF (2016) Bioenergetic profiling of platelet mitochondria during storage: 4°C storage extends platelet mitochondrial function and viability. Transfusion 56 Suppl 1:S76-84.LEAK
ROUTINE
ET
ROXIntact cellsHumanBlood cells
Platelet
Barison 2016 J Bioenerg Biomembr2016BarisĂłn MJ, Damasceno FS, Mantilla BS, Silber AM (2016) The active transport of histidine and its role in ATP production in Trypanosoma cruzi. J Bioenerg Biomembr 48:437-49.LEAK
ROUTINE
ET
Intact cellsProtists
Watala 2016 Int J Pharm2016Watala C, Karolczak K, Kassassir H, Siewiera K, Maczynska K, Pieniazek A, Labieniec-Watala M (2016) How do the full-generation poly(amido)amine (PAMAM) dendrimers activate blood platelets? Platelet membrane zeta potential and other membrane-associated phenomena. Int J Pharm 500:379-89.LEAK
ROUTINE
ET
ROXIntact cellsHumanBlood cells
Platelet
Chabot 2016 J Fish Biol2016Chabot D, McKenzie DJ, Craig JF (2016) Metabolic rate in fishes: definitions, methods and significance for conservation physiology. https://doi.org/10.1111/jfb.12873.ROUTINEFishes
Lores-Arnaiz 2016 Neurochem Res2016Lores-Arnaiz S, Lombardi P, Karadayian AG, Orgambide F, Cicerchia D, Bustamante J (2016) Brain cortex mitochondrial bioenergetics in synaptosomes and non-synaptic mitochondria during aging. Neurochem Res 41:353-63.LEAK
ROUTINE
OXPHOS
ET
N
S
Isolated mitochondria
Intact cells
MouseNervous system
Fonseca-Berzal 2016 Parasitology2016Fonseca-Berzal C, DA Silva CF, Menna-Barreto RF, Batista MM, Escario JA, ArĂĄn VJ, GĂłmez-Barrio A, Soeiro Mde N (2016) Biological approaches to characterize the mode of action of two 5-nitroindazolinone prototypes on Trypanosoma cruzi bloodstream trypomastigotes. Parasitology 143:1469-78.ROUTINEROXIntact organismProtists
Berschneider 2016 Thesis2016Berschneider K (2016) Connecting the functions of the proteasome and mitochondria in the lung. Dissertation p161.LEAK
ROUTINE
ET
ROXPermeabilized cellsMouseLung;gill
Alvarez-Mora 2016 Mol Neurobiol2016Alvarez-Mora MI, Rodriguez-Revenga L, Madrigal I, Guitart-Mampel M, Garrabou G, MilĂ  M (2016) Impaired mitochondrial function and dynamics in the pathogenesis of FXTAS. Mol Neurobiol 54:6896-902.ROUTINEN
S
NS
Intact cellsHumanFibroblast
Reynolds 2016 Am J Physiol Endocrinol Metab2016Reynolds MS, Hancock CR, Ray JD, Kener KB, Draney C, Garland K, Hardman J, Bikman BT, Tessem JS (2016) ÎČ-cell deletion of Nr4a1 and Nr4a3 nuclear receptors impedes mitochondrial respiration and insulin secretion. Am J Physiol Endocrinol Metab 311:E186-201.LEAK
ROUTINE
OXPHOS
ET
N
S
ROX
Permeabilized cells
Intact cells
RatIslet cell;pancreas;thymus
Liu 2016 Apoptosis2016Liu X, Gao RW, Li M, Si CF, He YP, Wang M, Yang Y, Zheng QY, Wang CY (2016) The ROS derived mitochondrial respiration not from NADPH oxidase plays key role in Celastrol against angiotensin II-mediated HepG2 cell proliferation. Apoptosis 21:1315-26.ROUTINEIntact cellsHumanLiver
Other cell lines
Sengupta 2016 Free Radic Biol Med2016Sengupta S, Yang G, O'Donnell JC, Hinson MD, McCormack SE, Falk MJ, La P, Robinson MB, Williams ML, Yohannes MT, Polyak E, Nakamaru-Ogiso E, Dennery PA (2016) The circadian gene Rev-erbα improves cellular bioenergetics and provides preconditioning for protection against oxidative stress. Free Radic Biol Med 93:177-89.LEAK
ROUTINE
ET
ROXIntact cellsMouseLung;gill
Fibroblast
Moll 2016 bioRxiv2016Moll CWI, Lindtner RA, Vogel GF, Brunner M, Gutleben K, Blauth M, Krumschnabel G, Ebner HL (2016) Bone marrow mesenchymal stem cells from osteoporotic patients do not show altered mitochondrial energetics or ultrastructure. bioRxiv doi.org/10.1101/046300.LEAK
ROUTINE
OXPHOS
ET
N
S
ROX
Intact cells
Permeabilized cells
HumanStem cells
Birkenmeier 2016 Int J Cancer2016Birkenmeier Katrin, Droese Stefan, Wittig Ilka, Winkelmann Ria, Kaefer Viktoria, Doering Claudia, Hartmann Sylvia, Wenz Tina, Reichert Andreas S, Brandt Ulrich, Hansmann Martin‐Leo (2016) Hodgkin and Reed-Sternberg cells of classical Hodgkin lymphoma are highly dependent on oxidative phosphorylation. Int J Cancer 138:2231-46.LEAK
ROUTINE
ET
ROXIntact cellsHumanOther cell lines
HeLa
Macrophage-derived
Svenkrtova 2016 Biogerontology2016Svenkrtova A, Belicova L, Volejnikova A, Sigler K, Jazwinski SM, Pichova A (2016) Stratification of yeast cells during chronological aging by size points to the role of trehalose in cell vitality. Biogerontology 17:395-408.ROUTINECIV
ROX
Intact cellsSaccharomyces cerevisiae
Barth 2016 Thesis2016Barth C (2016) Effekte einer intermittierenden Hyperoxie auf die mitochondriale Atmung in Alveolarmakrophagen. Dissertation p69.LEAK
ROUTINE
OXPHOS
N
S
CIV
NS
ROX
Permeabilized cells
Intact cells
MouseLung;gill
Macrophage-derived
Stier 2016 Methods Ecol Evol2016Stier A, Romestaing C, Schull Q, Lefol E, Robin JP, Roussel D, Bize P (2016) How to measure mitochondrial function in birds using red blood cells: a case study in the king penguin and perspectives in ecology and evolution. Methods Ecol Evol doi:10.1111/2041-210X.12724.LEAK
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OXPHOS
ET
N
S
ROX
Permeabilized tissue
Intact cells
BirdsSkeletal muscle
Blood cells
Lesage 2016 Am J Hum Genet2016Lesage S, Drouet V, Majounie E, Deramecourt V, Jacoupy M, Nicolas A, Cormier-Dequaire F, Hassoun SM, Pujol C, Ciura S, Erpapazoglou Z, Usenko T, Maurage CA, Sahbatou M, Liebau S, Ding J, Bilgic B, Emre M, Erginel-Unaltuna N, Guven G, Tison F, Tranchant C, Vidailhet M, Corvol JC, Krack P, Leutenegger AL, Nalls MA, Hernandez DG, Heutink P, Gibbs JR, Hardy J, Wood NW, Gasser T, Durr A, Deleuze JF, Tazir M, Destée A, Lohmann E, Kabashi E, Singleton A, Corti O, Brice A (2016) Loss of VPS13C function in autosomal-recessive parkinsonism causes mitochondrial dysfunction and increases PINK1/Parkin-Dependent Mitophagy. Am J Hum Genet 98:500-13.LEAK
ROUTINE
ET
ROXIntact cellsOther mammalsKidney
Other cell lines
Zhunussova 2016 PLOS ONE2016Zhunussova A, Vitol EA, Polyak B, Tuleukhanov S, Brooks AD, Sensenig R, Friedman G, Orynbayeva Z (2016) Mitochondria-mediated anticancer effects of non-thermal atmospheric plasma. PLOS ONE 11:e0156818.LEAK
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ET
Intact cellsHumanGenital
Other cell lines
Nauta 2016 Thesis2016Nauta TD (2016) HIF-2α regulates in vitro neovascularization during hypoxia. Doctoral Dissertation p206.LEAK
ROUTINE
ET
ROXIntact cellsHumanEndothelial;epithelial;mesothelial cell
Raturi 2016 J Cell Biol2016Raturi A, Gutiérrez T, Ortiz-Sandoval C, Ruangkittisakul A, Herrera-Cruz MS, Rockley JP, Gesson K, Ourdev D, Lou PH, Lucchinetti E, Tahbaz N, Zaugg M, Baksh S, Ballanyi K, Simmen T (2016) TMX1 determines cancer cell metabolism as a thiol-based modulator of ER-mitochondria Ca2+ flux. J Cell Biol 214:433-44.LEAK
ET
ROUTINE
Permeabilized cells
Intact cells
Mouse
Human
HeLa
Other cell lines
Davuluri 2016 J Physiol2016Davuluri G, Allawy A, Thapaliya S, Rennison JH, Singh D, Kumar A, Sandlers Y, Van Wagoner DR, Flask CA, Hoppel C, Kasumov T, Dasarathy S (2016) Hyperammonaemia-induced skeletal muscle mitochondrial dysfunction results in cataplerosis and oxidative stress. J Physiol 594:7341-60.LEAK
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ROXIntact cellsMouseSkeletal muscle
Other cell lines
Holandino 2016 Bioelectrochemistry2016Holandino C, Teixeira CA, de Oliveira FA, Barbosa GM, Siqueira CM, Messeder DJ, de Aguiar FS, da Veiga VF, Girard-Dias W, Miranda K, Galina A, Capella MA, Morales MM (2016) Direct electric current treatment modifies mitochondrial function and lipid body content in the A549 cancer cell line. Bioelectrochemistry 111:83-92.LEAK
ROUTINE
ET
ROXIntact cellsHumanLung;gill
Other cell lines
Anand 2016 PLOS ONE2016Anand R, Strecker V, Urbach J, Wittig I, Reichert AS (2016) Mic13 is essential for formation of crista junctions in mammalian cells. PLOS ONE 11:e0160258.LEAK
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ET
N
CIV
NS
Other combinations
ROX
Permeabilized cells
Intact cells
HEK
Bastow 2016 J Cell Sci2016Bastow EL, Peswani AR, Tarrant DS, Pentland DR, Chen X, Morgan A, Staniforth GL, Tullet JM, Rowe ML, Howard MJ, Tuite MF, Gourlay CW (2016) New links between SOD1 and metabolic dysfunction from a yeast model of amyotrophic lateral sclerosis. J Cell Sci 129:4118-29.LEAK
ROUTINE
ET
ROXIntact cellsSaccharomyces cerevisiae
Puskarich 2016 J Crit Care2016Puskarich MA, Kline JA, Watts JA, Shirey K, Hosler J, Jones AE (2016) Early alterations in platelet mitochondrial function are associated with survival and organ failure in patients with septic shock. J Crit Care 31:63-7.LEAK
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ET
ROXIntact cellsHumanBlood cells
Platelet
Wos 2016 Arch Biochem Biophys2016Woƛ M, Szczepanowska J, PikuƂa S, Tylki-SzymaƄska A, ZabƂocki K, Bandorowicz-PikuƂa J (2016) Mitochondrial dysfunction in fibroblasts derived from patients with Niemann-Pick type C disease. Arch Biochem Biophys 593:50-9.LEAK
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ET
Intact cellsHumanEndothelial;epithelial;mesothelial cell
Fibroblast
Oliveira 2016 PLOS ONE2016Oliveira MP, Correa Soares JB, Oliveira MF (2016) Sexual preferences in nutrient utilization regulate oxygen consumption and reactive oxygen species generation in Schistosoma mansoni: potential implications for parasite redox biology. PLOS ONE 11:e0158429.LEAK
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F
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Intact organismOther invertebrates
Mesquita 2016 Thesis2016Mesquita Rodrigues C (2016) Efeito da depleção de ferro sobre Leishmania (Viannia) braziliensisuma anålise ultraestrutural, proteÎmica e interação com matrizes de colågeno sintéticas. Doctoral Dissertation p210.ROUTINEROXIntact cellsProtists
Heimer 2016 Am J Hum Genet2016Heimer G, KerÀtÀr JM, Riley LG, Balasubramaniam S, Eyal E, PietikÀinen LP, Hiltunen JK, Marek-Yagel D, Hamada J, Gregory A, Rogers C, Hogarth P, Nance MA, Shalva N, Veber A, Tzadok M, Nissenkorn A, Tonduti D, Renaldo F, Kraoua I, Panteghini C, Valletta L, Garavaglia B, Cowley MJ, Gayevskiy V, Roscioli T, Silberstein JM, Hoffmann C, Raas-Rothschild A, Tiranti V, Anikster Y, Christodoulou J, Kastaniotis AJ, Ben-Zeev B, Hayflick SJ (2016) MECR mutations cause childhood-onset dystonia and optic atrophy, a mitochondrial fatty acid synthesis disorder. Am J Hum Genet 99:1229-44.LEAK
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ROXIntact cellsHumanFibroblast
Jang 2016 Clin Toxicol (Phila)2016Jang DH, Shofer FS, Weiss SL, Becker LB (2016) Impairment of mitochondrial respiration following ex vivo cyanide exposure in peripheral blood mononuclear cells. Clin Toxicol (Phila) 54:303-7.LEAK
ROUTINE
ET
ROXIntact cellsHumanBlood cells
Lymphocyte
Sanchez-Calvo 2016 PLOS ONE2016SĂĄnchez-Calvo B, Cassina A, Rios N, Peluffo G, Boggia J, Radi R, Rubbo H, Trostchansky A (2016) Nitro-arachidonic acid prevents Angiotensin II-induced mitochondrial dysfunction in a cell line of kidney proximal tubular cells. PLOS ONE 11:e0150459.LEAK
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ROXIntact cellsHumanKidney
Other cell lines
Jang 2016 J Intensive Care Med2016Jang DH, Greenwood JC, Spyres MB, Eckmann D (2016) Measurement of mitochondrial respiration and motility in acute care: sepsis, trauma, and poisoning. J Intensive Care Med 32:86-94.LEAK
ROUTINE
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ROXIntact cellsHumanBlood cells
Lymphocyte
McFarlane 2016 Thesis2016McFarlane SV (2016) Temperature-dependent alterations of brown adipose tissue metabolism during hibernation in the thirteen-lined ground squirrel, Ictidomys tridecemlineatus. Dissertation p74.LEAK
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ET
F
N
Isolated mitochondria
Intact cells
Other mammalsFat
Ehinger 2016 Mov Disord2016Ehinger JK, Morota S, Hansson MJ, Gesine P, ElmĂ©r E (2016) Mitochondrial respiratory function in peripheral blood cells from Huntington’s disease patients. Mov Disord doi:10.1002/mdc3.12308.LEAK
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ET
N
S
CIV
NS
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ROX
Permeabilized cells
Intact cells
HumanBlood cells
Lymphocyte
Platelet
Scrima 2016 Biochim Biophys Acta2016Scrima R, Cela O, Merla G, Augello B, Rubino R, Quarato G, Fugetto S, Menga M, Fuhr L, RelĂłgio A, Piccoli C, Mazzoccoli G, Capitanio N (2016) Clock-genes and mitochondrial respiratory activity: Evidence of a reciprocal interplay. Biochim Biophys Acta 1857:1344-51.LEAK
ROUTINE
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ROXIntact cellsHumanLiver
Endothelial;epithelial;mesothelial cell
Other cell lines
Fibroblast
Shao 2016 Cell Res2016Shao LW, Niu R, Liu Y (2016) Neuropeptide signals cell non-autonomous mitochondrial unfolded protein response. Cell Res 26:1182-96.ROUTINEIntact organismCaenorhabditis elegans
Peruzzo 2016 Cell Cycle2016Peruzzo P, Comelli M, Di Giorgio E, Franforte E, Mavelli I, Brancolini C (2016) Transformation by different oncogenes relies on specific metabolic adaptations. Cell Cycle 15:2656-68.LEAK
ROUTINE
ET
ROXIntact cellsMouseFibroblast
Chubanov 2016 Elife2016Chubanov V, Ferioli S, Wisnowsky A, Simmons DG, Leitzinger C, Einer C, Jonas W, Shymkiv Y, Bartsch H, Braun A, Akdogan B, Mittermeier L, Sytik L, Torben F, Jurinovic V, van der Vorst EP, Weber C, Yildirim ÖA, Sotlar K, SchĂŒrmann A, Zierler S, Zischka H, Ryazanov AG, Gudermann T (2016) Epithelial magnesium transport by TRPM6 is essential for prenatal development and adult survival. Elife 5. pii: e20914.ROUTINE
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ROXIntact cellsHumanFibroblast
Other cell lines
Siewiera 2016 Life Sci2016Siewiera K, Kassassir H, Talar M, Wieteska L, Watala C (2016) Higher mitochondrial potential and elevated mitochondrial respiration are associated with excessive activation of blood platelets in diabetic rats. Life Sci 148:293-304.LEAK
ROUTINE
ET
ROXIntact cellsRatBlood cells
Platelet
Gerber 2016 J Med Genet2016Gerber S, Ding MG, GĂ©rard X, Zwicker K, Zanlonghi X, Rio M, Serre V, Hanein S, Munnich A, Rotig A, Bianchi L, Amati-Bonneau P, Elpeleg O, Kaplan J, Brandt U, Rozet JM (2016) Compound heterozygosity for severe and hypomorphic NDUFS2 mutations cause non-syndromic LHON-like optic neuropathy. J Med Genet 54:346-56.LEAK
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ET
ROXIntact cellsHumanEndothelial;epithelial;mesothelial cell
Fibroblast
Vevera 2016 Physiol Res2016Vevera J, Fiơar Z, Nekováƙová T, Vrablík M, Zlatohlávek L, Hroudová J, Singh N, Raboch J, Valeơ K (2016) Statin-induced changes in mitochondrial respiration in blood platelets in rats and human with dyslipidemia. Physiol Res 65:777-88.LEAK
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OXPHOS
ET
N
S
NS
Other combinations
ROX
Intact cells
Permeabilized cells
Human
Rat
Blood cells
Platelet
Safiedeen 2016 Antioxid Redox Signal2016Safiedeen Z, RodrĂ­guez-GĂłmez I, Vergori L, Soleti R, Vaithilingam D, Douma I, Agouni A, Leiber D, Dubois S, Simard G, Zibara K, Andriantsitohaina R, MartĂ­nez MC (2016) Temporal cross talk between endoplasmic reticulum and mitochondria regulates oxidative stress and mediates microparticle-induced endothelial dysfunction. Antioxid Redox Signal 26:15-27.LEAK
ET
ROUTINE
ROXIntact cellsHumanEndothelial;epithelial;mesothelial cell
Frey 2016 Biochim Biophys Acta2016Frey S, Geffroy G, Desquiret-Dumas V, Gueguen N, Bris C, Belal S, Amati-Bonneau P, Chevrollier A, Barth M, Henrion D, Lenaers G, Bonneau D, Reynier P, Procaccio V (2016) The addition of ketone bodies alleviates mitochondrial dysfunction by restoring complex I assembly in a MELAS cellular model. Biochim Biophys Acta 1863:284-91.ROUTINE
LEAK
ET
N
S
NS
Permeabilized cells
Intact cells
HumanNervous system
Maarman 2016 J Appl Physiol (1985)2016Maarman GJ, Andrew BM, Blackhurst DM, Ojuka EO (2016) Melatonin protects against uric acid-induced mitochondrial dysfunction, oxidative stress, and triglyceride accumulation in C2C12 myotubes. J Appl Physiol (1985) 122:1003-10.LEAK
ROUTINE
OXPHOS
ET
N
S
CIV
NS
ROX
Permeabilized cells
Intact cells
MouseSkeletal muscle
Gdynia 2016 Nat Commun2016Gdynia G, Sauer SW, Kopitz J, Fuchs D, Duglova K, Ruppert T, Miller M, Pahl J, Cerwenka A, Enders M, MairbĂ€url H, KamiƄski MM, Penzel R, Zhang C, Fuller JC, Wade RC, Benner A, Chang-Claude J, Brenner H, Hoffmeister M, Zentgraf H, Schirmacher P, Roth W (2016) The HMGB1 protein induces a metabolic type of tumour cell death by blocking aerobic respiration. Nat Commun 7:10764.ROUTINEROXPermeabilized cellsHumanEndothelial;epithelial;mesothelial cell
Other cell lines
Zelenka 2016 Oxid Med Cell Longev2016Zelenka J, Dvoƙák A, Alán L, Zadinová M, Haluzík M, Vítek L (2016) Hyperbilirubinemia protects against aging-associated inflammation and metabolic deterioration. Oxid Med Cell Longev ID 6190609:10p.ROUTINEIntact cells
Isolated mitochondria
RatLiver
Kidney
Fibroblast
Giraldos Jimenez 2016 Thesis2016Giraldos JimĂ©nez D (2016) Oxidative phosphorylation system’s role in adipogenic differentiation. Thesis p25.LEAK
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ROX
Schiffer 2016 Am J Physiol Cell Physiol2016Schiffer TA, Peleli M, Sundqvist ML, Ekblom B, Lundberg JO, Weitzberg E, Larsen FJ (2016) Control of human energy expenditure by cytochrome c oxidase subunit IV-2. Am J Physiol Cell Physiol 311:C452-61.LEAK
OXPHOS
ET
ROUTINE
N
NS
Permeabilized cells
Isolated mitochondria
Intact cells
HumanSkeletal muscle
HEK