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• Unspecific binding of TPP+
  ...ding outside of the inner mt-membrane or on the outer side of the inner mt-membrane, in contrast to internal unspecific binding. |info=[[Mitochondrial membrane potential]]
  527 bytes (71 words) - 00:03, 18 February 2020
• TPP+ inhibitory effect
  ...required to evaluate the necessary limit of detection of TPP⁺, and for restriction of experimental TPP⁺ concentrations below the in {{Keywords: Force and membrane potential}}
  773 bytes (102 words) - 00:03, 18 February 2020
• Uncoupler
  ...847]]) which cycles across the inner mt-membrane with transport of protons and dissipation of the electrochemical proton gradient. Mild uncoupling may be {{Keywords: Uncoupling}}
  755 bytes (88 words) - 11:05, 28 March 2024
• O2k-TPP+ ISE-Module
  ...ometric ion-selective electrodes for measurement of mitochondrial membrane potential ...//www.oroboros.at/index.php/product/o2k-tpp-ise-module/ '''Product details and purchase information''']
  1,012 bytes (118 words) - 11:49, 17 August 2022
• O2k-Publications: mt-Membrane potential
  ...Publications]] [[Instrument and method::Oxygraph-2k]] [[Topic::mt-Membrane potential]] |?Mammal and model=Organism
  1 KB (184 words) - 00:09, 18 February 2020
• MitoEAGLE preprint 2017-09-21
  |title=MitoEAGLE preprint 2018-02-18(21) The protonmotive force and respiratory control. ...owing a primary peer-reviewed publication of the concept of stoichiometric potential differences.
  3 KB (369 words) - 12:48, 23 May 2020
• Klusch 2017 Elife
  ...Yildiz Ö, Kühlbrandt W (2017) Structural basis of proton translocation and force generation in mitochondrial ATP synthase. Elife e33274. doi: 10.7554/eLife. ...e steep potential gradient over the sub-nm inter-channel distance exerts a force on the deprotonated glutamate, resulting in net directional rotation.
  2 KB (220 words) - 17:22, 16 January 2021
• Mitochondrial membrane potential
  ...u>''e''</u>p⁺</sub>, is the electric part of the protonmotive [[force]], Δp = Δ_m''F''_{<u>''e''</u>H⁺}. ...gy change per ‘motive’ charge or per charge moved across the transmembrane potential difference, with the number of ‘motive’ charges expressed in the unit c
  6 KB (847 words) - 17:02, 17 January 2024
• Komlodi 2022 MitoFit
  ...e=Komlódi T, Tretter L (2022) The protonmotive force – not merely membrane potential. https://doi.org/10.26124/mitofit:2022-0012 — ''2022-11-29 published in [ ...di_2022_MitoFit_Preprints.pdf The protonmotive force - not merely membrane potential] [[File:WatchThePresentationYoutube_icon.jpg|200px|link=https://www.youtube
  3 KB (405 words) - 16:58, 4 July 2023
• Komlodi 2022 BEC
  ...e=Komlódi T, Tretter L (2022) The protonmotive force – not merely membrane potential. Bioenerg Commun 2022.16. https://doi.org/10.26124/bec:2022-0016 ...eactive oxygen species production. Measurement of both Δ''Ψ''_mt and ΔpH allows for calculation of ''pmF''. Methods for monitoring Δ''Ψ''<sub
  3 KB (410 words) - 07:00, 8 January 2023
• Komlodi 2022 Abstract Bioblast
  ...i Timea</u>, Tretter L (2022) The protonmotive force – not merely membrane potential. '''Bioblast 2022: BEC Inaugural Conference.''' In: https://doi.org/10.2612 ...ve oxygen species production. Separate measurement of Δ''Ψ''_mt and ΔpH allows for calculation of ''pmF''. Methods for monitoring Δ''Ψ''<sub
  3 KB (394 words) - 08:30, 28 July 2022
• Ghelli 1997 J Biochem
  |title=Ghelli A, Benelli B, Esposti MD (1997) Measurement of the membrane potential generated by Complex I in submitochondrial particles. J Biochem 121: 746-55 ...complex reducing endogenous ubiquinone (i.e. non-steady-state conditions) and are equivalent to a charge separation similar to that of the antimycin-sens
  2 KB (254 words) - 16:41, 7 November 2016
• Quarato 2011 Biochim Biophys Acta
  ...the other respiratory chain complexes at different values of protonmotive force occurs by a threshold mechanism. Biochim Biophys Acta 1807: 1114-1124. ...e-mediated threshold-controlled dynamic equilibrium between supercomplexed and isolated states.
  2 KB (284 words) - 09:56, 8 November 2017
• Polster 2014 Methods Enzymol
  ...difficult to impossible. Consequently, knowledge of mitochondrial membrane potential is essential to the application of potentiometric fluorophores for the meas ...hydroethidine, dihydroethidium, triphenylphosphonium, superoxide, membrane potential, ROS, Seahorse, respiration, uncoupling
  2 KB (290 words) - 10:57, 28 September 2018
• Stoichiometric number
  ...'ν''_A=-1/6 in the reaction 0 = -1/6 A - 1 B + 1 C (-1/6 glucose and -1 O₂ converted to +1 H₂CO₃). {{Keywords: Force and membrane potential}}
  704 bytes (112 words) - 05:44, 16 September 2022
• Mitchell 1969 Eur J Biochem
  ...969) Estimation of membrane potential and pH difference across the cristae membrane of rat liver mitochondria. Eur J Biochem 7:471-84. ...and the change of these values in the transition from State 5 to States 4 and 3.
  3 KB (410 words) - 12:16, 28 May 2015
• Glancy 2013 Biochemistry
  ...old), Complexes I and III (2.2-fold), ATP production/transport (2.4-fold), and fuel transport/dehydrogenases (1.7-fold). These data support the notion tha |keywords=Metabolic homeostasis, Bioenergetics, Electron transport chain, Cytochrome
  3 KB (344 words) - 14:19, 13 November 2017
• MitoPedia: Ergodynamics
  ...near laws of TIP — implying linear relations between the generalized flows and forces called the ''phenomenological relations'' [2] — must primarily be ...ility of phenomenological coefficients ''L'' non-linearly dependent on the force under simple experimental conditions [3]. This shatters the foundation of t
  2 KB (312 words) - 21:34, 15 October 2022
• Protonmotive force
  ...is a potential for the movement of protons, and force is a measure of the potential for motion. ...e there is no absolute potential, but isomorphic forces are stoichiometric potential differences^§.
  7 KB (1,194 words) - 21:50, 10 July 2022
• Komlodi 2018 J Bioenerg Biomembr
  ...everse electron transport-associated hydrogen peroxide production in brain and heart mitochondria. J Bioenerg Biomembr 50:355-365
  3 KB (439 words) - 04:34, 19 July 2022
• BEC tutorial-Living Communications: pmF to pmP
  :::: '''Mitochondrial membrane potential and Peter Mitchell’s protonmotive force ''pmF'': elements of the science of bioenergetics''' ...tps://doi.org/10.26124/bec:2020-0002 - '''Chapter 8: Protonmotive pressure and respiratory control'''
  9 KB (1,076 words) - 13:10, 18 October 2022
• Goo 2013 Clin Exp Pharmacol Physiol
  ...rmation on oxygen consumption, ATP flux, membrane potential, electron leak and reactive oxygen species production, the latter two of which index energy tr ...rdiac enthalpy production, Cardiac heat production, Mitochondrial membrane potential, Mitochondrial proton leak, Mitochondrial reactive oxygen species productio
  2 KB (222 words) - 11:40, 9 February 2022
• Devin 1997 Biochim Biophys Acta
  ...ng systems (cytochrome c oxidase) and decreased on one of the protonmotive force dissipating systems (adenine nucleotide translocator), even if the fluxes i |keywords=Oxidative phosphorylation efficiency, Kinetic control, Ionic media, Cytochr
  2 KB (285 words) - 13:52, 15 January 2020
• Sumbalova 2011 Abstract Kagoshima
  ...mbrane potential, coupling control, H₂O₂ production, and the upper limit of mitochondrial performance. Abstract Kagoshima. ...passive LEAK state of respiration. The upper limit of respiratory capacity and the scope of ROS signalling, therefore, are significantly higher under cond
  3 KB (457 words) - 18:18, 10 January 2022
• Lane 2022 Abstract Bioblast
  ...lpha and omega of metabolism: why the Krebs cycle brings the earth to life and our own lives to an end. '''Bioblast 2022: BEC Inaugural Conference.''' In: ...organisms, including bacteria, in which fluctuations in membrane potential and the electrical fields generated amount to real-time integrated feedback on
  3 KB (471 words) - 08:26, 28 July 2022
• Chemical potential
  ...r amount of B, ''n''_B [mol], at constant temperature, pressure, and composition other than that of B, ...e sum of the standard chemical potential under defined standard conditions and a concentration ([[activity]])-dependent term,
  3 KB (498 words) - 00:13, 18 February 2020
• Rhodamine 123
  ...534 nm. The recommended excitation and emission wavelengths in PBS are 488 and 515-575 nm, respectively (Sigma-Aldrich). ::::# Weight 1.9 mg of Rh123 and dissolve in 1 mL ethanol;
  5 KB (698 words) - 15:50, 16 March 2021
• Krumschnabel 2014 Methods Enzymol
  ...ssment of mitochondrial membrane potential by high-resolution respirometry and fluorometry. Methods Enzymol 542:163-81. https://doi.org/10.1016/B978-0-12- ...rophore applied for probing mtMP, in any respiratory state, type of tissue and pathophysiological condition.
  5 KB (600 words) - 21:53, 23 April 2024
• Mitchell 2011 Biochim Biophys Acta
  |title=Mitchell P (1966) Chemiosmotic coupling in oxidative and photosynthetic phosphorylation. Biochim Biophys Acta Bioenergetics 1807 (20 ...issue by Peter R. Rich. Original title: CHEMIOSMOTIC COUPLING IN OXIDATIVE AND PHOTOSYNTHETIC PHOSPHORYLATION, by Peter Mitchell, Glynn Research Laborator
  6 KB (899 words) - 11:57, 9 May 2024
• Krause 2023 J Transl Med
  ...sing its ''in vitro'' effects on cardiac electrophysiology and metabolism, and translated our findings into the human setting. ...ents, high C18:1AC serum concentrations were associated with the incidence and prevalence of AF.
  3 KB (418 words) - 15:47, 30 August 2023
• O2k-Publications: Coupling efficiency;uncoupling
  {{#ask:[[Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[Topic::Coupling efficiency;uncoupling]] |?Mammal and model=Organism
  1 KB (188 words) - 00:04, 18 February 2020
• Breton-Romero 2014 Biochim Biophys Acta
  ...nar shear stress regulates mitochondrial dynamics, bioenergetics responses and PRX3 activation in endothelial cells. Biochim Biophys Acta 1843:2403-13. ...a in endothelial cells as active players, able to transduce the mechanical force of shear stress in the vascular endothelium into a biological response.
  2 KB (304 words) - 15:56, 9 November 2016
• Gnaiger 1993 Pure Appl Chem
  ...d forces. For illustration, analogous electric, thermal and chemical flows and forces are represented. ...thermodynamics with reference to entropy production, '''[[efficiency]]''' and '''energy dissipation'''. The symbols of nonequilibrium thermodynamics are
  4 KB (655 words) - 13:53, 1 May 2024
• Jezek 2018 Antioxid Redox Signal
  ...physiology and pathology. Moreover, UCP2-mediated aspartate, oxaloacetate, and malate antiport with phosphate is expected to alter metabolism of cancer ce CRITICAL ISSUES: A wide range of UCP antioxidant effects and participations in redox signaling have been reported; however, mechanisms o
  3 KB (346 words) - 18:40, 16 January 2021
• Gnaiger 2018 MiPschool Tromso A2
  ...=[[File:Erich Gnaiger.jpg|left|90px|Erich Gnaiger]] The protonmotive force and respiratory control. 1. Coupling of electron transfer reactions to vectoria ...bs energy change per [[advancement]] of reaction [3]. For the protonmotive force the proton is the motive entity, which can be expressed in a variety of for
  8 KB (1,154 words) - 14:59, 13 February 2020
• Garlid KD 2012 Abstract Bioblast
  ...and I will review recent progress in understanding the K⁺ cycle and its role in the cell. ...66.tb01501.x/abstract Mitchell P (2008) Chemiosmotic coupling in oxidative and photosynthetic phosphorylation. Biol Rev 41: 445-501.]
  4 KB (506 words) - 16:24, 25 November 2015
• Advancement
  ...rtmental diffusion (spontaneous from a high-potential compartment to a low-potential compartment), the advancement is the amount of motive substance that has un ...d to compartmental diffusion and the advancement of charged particles [3], and to any discontinuous transformation in compartmental systems [2],
  6 KB (952 words) - 04:30, 20 March 2023
• Pressure
  ...the [[force]] at the point of [[action]]. More generally, pressure is the force times concentration at the interphase of interaction. |info=* Gnaiger E (2020) Mitochondrial pathways and respiratory control. An introduction to OXPHOS analysis. 5^th ed.
  7 KB (1,053 words) - 07:05, 6 July 2023
• Uncoupling proteins
  ...dissipating the electrochemical proton gradient ([[mitochondrial membrane potential]]), generated by the [[electron transfer pathway]] by pumping protons from ...n elicited by cold exposure, including ROS and lipid metabolism, apoptosis and thermogenesis.<ref>Criscuolo F, Gonzalez‐Barroso MdM, Bouillaud F, Ricqui
  4 KB (559 words) - 14:23, 8 June 2020
• Bustamante 2012 Alcohol
  ...ian AG, Lores-Arnaiz S, Cutrera RA (2012) Alterations of motor performance and brain cortex mitochondrial function during ethanol hangover. Alcohol 46:473 ...of animals could be associated with brain cortex mitochondrial dysfunction and the resulting impairment of its energetic metabolism.
  3 KB (368 words) - 10:30, 13 February 2015
• Alencar 2022 BEC
  ...abolism of the bloodstream ''Trypanosoma brucei'' forms: a critical review and hypothesis. Bioenerg Commun 2022.17. https://doi.org/10.26124/bec:2022-0017 ...bolic design” in BSF has no biological parallel outside of trypanosomatids and highlights the enormous diversity of the parasite mitochondrial processes t
  3 KB (445 words) - 07:00, 8 January 2023
• Rodrigues-Ferreira 2012 J Bioenerg Biomembr
  ...a by a proton motive force-dependent dynamic equilibrium between sensitive and less sensitive SDH in the electron transport system. |keywords=hepatocarcinoma cell line HepG2, alkylating agent 3-Bromopyruvate (3-BrPA)
  3 KB (370 words) - 14:23, 9 November 2016
• Grundmanova 2016 Physiol Res
  ...i A, Čedíková M, Štengl M, Kuncová J (2016) Propofol-induced mitochondrial and contractile dysfunction of the rat ventricular myocardium. Physiol Res 65:S ...ary muscle contraction force at 0.1 mmol/l. Propofol did not affect action potential duration at any concentration studied. Our study suggests that mechanisms c
  3 KB (364 words) - 12:33, 22 November 2017
• Tarpey 2019 J Biol Chem
  ...ubicin-induced lesions likely span mitochondrial complexes I-IV, providing potential targets for alleviating doxorubicin myotoxicity. <small>Published under license by The American Society for Biochemistry and Molecular Biology, Inc.</small>
  3 KB (393 words) - 11:24, 3 March 2020
• Ergodynamics
  ...modynamics of irreversible processes (TIP; nonequilibrium thermodynamics), and thus links thermodynamics to kinetics. In its most general scope, ergodynam ...near laws of TIP — implying linear relations between the generalized flows and forces called the ''phenomenological relations'' [5] — must primarily be
  4 KB (555 words) - 21:33, 15 October 2022
• Force
  ...cement]] is the [[work]] (exergy) expended in a process or transformation. Force times flow is [[power]] [W]. ...the resistance is entirely due to frictional effects, then no work is done and the exergy is completely dissipated.
  17 KB (2,612 words) - 06:35, 9 February 2024
• EBEC2014
  == Sponsor and exhibitor == ...ip between cytochrome redox state and oxygen consumption in isolated mouse and beef heart mitochondria during hypoxia. EBEC2014.
  5 KB (720 words) - 12:35, 23 January 2019
• Treberg 2018 Redox Biol
  ...is a function of both mitochondrial H₂O₂ consumption and production capacity, the latter of which is strongly influenced by ΔΨ. Ou |keywords=Antioxidants, Energy sensing, Peroxidase, Peroxiredoxins, Reactive oxygen s
  3 KB (396 words) - 13:35, 7 March 2020
• McLaughlin 2018 Biochem Biophys Res Commun
  ...ced phenotype appears to result from specific reductions in both complex I and complex IV expression, presumably due to compromised mtDNA integrity. Trans |keywords=Bioenergetics, DNA polymerase gamma, Heart, Mitochondrial DNA, Reactive oxy
  2 KB (319 words) - 11:29, 14 January 2019
• Dlaskova 2008 Int J Biochem Cell Biol
  ...II substrates. Sole 5-(N-ethyl-N-isopropyl) amiloride alone suppressed 20% and 30% of total H₂O₂ production, respectively, under th |keywords=Mitochondrial H₂O₂ production, Uncoupling, Proton-pum
  3 KB (360 words) - 15:45, 20 March 2015

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