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...Chao T, Reidy PT, Rasmussen BB, Andersen CR, Suman OE, Sidossis LS. (2016) Long-Term Skeletal Muscle Mitochondrial Dysfunction is Associated with Hypermeta ...ive derangements in skeletal muscle bioenergetics likely contribute to the long-term pathophysiological stress response to burn trauma.

..., Koch K, Franke N, Klein J, Eckert GP (2016) Intravenous treatment with a long-chain omega-3 lipid emulsion provides neuroprotection in a murine model of ...to control experiments, neuroprotective effects could be attributed to the long-chain omega-3 content of the emulsion. Intravenous injection of OGV reduced

...cription='''Palmitoylcarnitine''' is an ester derivative of [[carnitine]] (long-chain acylcarnitine) involved in the metabolism of fatty acids. Within the ...ciated with the outer mitochondrial membrane and mediates the transport of long-chain fatty acids across the membrane by binding them to carnitine.

...uire the carnitine shuttle for transport into mitochondria. In contrast to long-chain fatty acids, the transport of short- and medium-chain fatty acids is ::::# Weigh 5 mg etomoxir.

|title=Mejia JF, Hirschi KM, Tsai KYF, Long MG, Tullis BC, Bitter EEK, Bikman BT, Reynolds PR, Arroyo JA (2019) Differenti |authors=Mejia JF, Hirschi KM, Tsai KYF, Long MG, Tullis BC, Bitter EEK, Bikman BT, Reynolds PR, Arroyo JA

...g the release of endogenous Mg²⁺. But contrary to nonesterified long-chain fatty acids, phytanic acid only slightly stimulates the conductance o |keywords=Mg²⁺, Mitochondria, Permeability Transition, Phytanic Acid, Refsum

|title=Sabia S, Kivimaki M, Shipley MJ, Marmot MG, Singh-Manoux A (2009) Body mass index over the adult life course and cogni |authors=Sabia S, Kivimaki M, Shipley MJ, Marmot MG, Singh-Manoux A

...permease of plasma membrane is the key transmembrane transport protein for long chain fatty acids (FA). In the last years, conflicting results have been pu ...oxidation in BAT from SHR and SHR-Cd36 rats (2.1±0.1 vs. 2.1±0.1 nmol palm/mg prot/2h), suggesting that CD36 is not important for FA transport into mitoc

...rga S, Gukalova B, Sevostjanovs E, Liepinsh E, Dambrova M (2023) Decreased long-chain acylcarnitine content increases mitochondrial coupling efficiency and ...etreatment with methyl-GBB (5 mg/kg, p.o.) on brain acylcarnitine (short-, long- and medium-chain) concentrations and brain mitochondrial function were eva

...minor beneficial effect on brain ATP levels and memory of aged mice. Life-long PGE feeding led to a transient but significant shift of survival curve towa

|title=Lai N, Kummitha CM, Rosca MG, Fujioka H, Tandler B, Hoppel CL (2019) Isolation of mitochondrial subpopul |authors=Lai N, Kummitha CM, Rosca MG, Fujioka H, Tandler B, Hoppel CL

...mpairment of bioenergetic capacity. Enalapril (10 mg/kg/d) or losartan (30 mg/kg/d) administered during 16.5 months were unable to prevent the age-depend

...rial impairment could result from oxidative stress-induced accumulation of MG and/or AGEs. Further investigations demonstrated that human plasma AGE accu

...K, Jeong SH, Lee S, Youm JB, Song IS, Seo DY, Kim HJ, Won DN, Cho KI, Choi MG, Rhee BD, Ko KS, Kim N, Won JC, Han J (2018) Resistance exercise improves c ...K, Jeong SH, Lee S, Youm JB, Song IS, Seo DY, Kim HJ, Won DN, Cho KI, Choi MG, Rhee BD, Ko KS, Kim N, Won JC, Han J

...rgan dysfunction, mitochondrial respiration and inflammatory response in a long-term model of fecal peritonitis. ...ate 3 respiration increased from 1357 ± 149 pmol/s/mg to 1822 ± 385 pmol/s/mg, (''P'' = 0.020). In high- and low-MAP groups, permeabilized skeletal muscl

...palmitoyl-CoA (+carnitine and malate) were inhibited at 1-2 nmol PA22 per mg mitochondrial protein. These data indicate that PA22 is selective for the f ...ns described above, mitochondrial inner membrane (mtIM) proteins, the very-long chain acyl-CoA dehydrogenase, the phosphate carrier, and the adenine nucleo

|description='''Carnitine''' is an important factor for the transport of long-chain fatty acids bound to carnitine ([[carnitine acyltransferase]]) into t ::::# Weigh 100 mg of Carnitine.

|title=Lai N, M Kummitha C, Rosca MG, Fujioka H, Tandler B, Hoppel CL (2018) Isolation of mitochondrial subpopul |authors=Lai N, M Kummitha C, Rosca MG, Fujioka H, Tandler B, Hoppel CL

...to be associated with a high cumulative dose of DOX, the mechanisms of its long-term effects have not been completely elucidated. Pioglitazone (Pio) is pre ...model (day 35), the mice were administrated DOX once a week for 5 weeks (5 mg/kg BW/week, i.p.).

...trol supplementation combined with exercise while also informing about the long-term clinical viability of the intervention by evaluating participant safet

...vans Tokushima Otsuka (LETO) rats received either control or L-NAME (65-70 mg/kg/day) containing drinking water for 4-wks. L-NAME treatment significantly

...f young individuals [3,4], but it remains to be established to what extent long-term bed rest induces qualitative and quantitative alterations in mitochond ...from the ''vastus lateralis'' muscle at day -1, 5 and 55. Approximately 12 mg of each muscle biopsy was mechanically separated and permeabilised, followe

...ATP impurities, we use this (Merck-Calbiochem) ADP for preparation of 'ADP-Mg' solution in [[AT_Innsbruck_Oroboros |Oroboros Lab]]. :::: To keep free [Mg²⁺] constant during respiration measurement in [[MiR06]] or MiR

|authors=White Sarah Haverty, Long CR, Randel RD, Welsh TH ...atest citrate synthase activity across muscle groups (9.49 ± 0.70 nmol/min*mg tissue) compared to T1 (6.44 ± 0.68; P = 0.009) or T2 (5.29 ± 0.59; P = 0

were treated telmisartan at 5 mg/kg/day orally or without telmisartan as monocytes from SHRs compared to WKYs. Long-term of telmisartan

...MiPsocietyLOGO.JPG|left|90px|Mitochondrial Physiology Society|MiPsociety]] Long-term sildenafil treatment improves expression of the main mitochondrial dyn ...ted orally for 6 months till old-age (18 months-old) with sildenafil (1.25 mg/kg body weight per day) while control group of rats received water.

...itation, may cause respiratory irritation, very toxic to aquatic life with long-lasting effects}}<!--:::'''Rot: Rotenone''' (C₂₃H₂₂O< ::::# Weigh about 1 mg of rotenone.

...ility, cellular respiration and lactate production under short, medium and long-term incubation periods. ...-dependent manner. Short-term incubation had no effect whereas medium- and long-term incubation induced a maximum of 30% and of 70% reduction in viability,

::::# Weigh 551.1 mg of ATP (M_{anhydrous basis} = 551.1 g·mol^-1). ::::# Store at -20 °C (-80 °C should be preferred for long-time storage).

...skin burns and eye damage, may cause an allergic skin reaction, may cause long-lasting harmful effects to aquatic life ...C₁₀H₅F₃N₄O); Sigma C 2920, 10 mg, store at 4 °C: M = 254.17 g·mol^-1)-->

...gh prolonged or repeated exposure (brain), very toxic to aquatic life with long-lasting effects ::::# Weigh 260 mg of sodium azide.

...ondria from male C57BL/6 mice treated with intraperitoneal injection of 10 mg/kg/day of CQ for 14 days, CQ was found to impair substrate-mediated mitocho

...pe was tested in 30 healthy volunteers. A self-adhesive patch containing 2 mg 5-aminolevulinic acid (ALA) was applied on the skin of the anterior chest w ...34°C and 40°C, respectively. No major discomfort during measurement and no long-term dermatological abnormalities were reported in a survey performed 1 mon

...may contribute to increased vulnerability of brain tissue in hypertension. Long-term treatment with AT1R blockers may prevent brain dysfunction in hyperten

...ically controlled pumps to deliver a dose of SS-31 peptide equivalent to 3 mg/kg of body mass per day for 4 or 8 weeks to 7 and 26-month old mice. After

...ory chain nor de novo protein synthesis was required for these medium- and long-term effects. As de novo lipid synthesis may be involved in ethanol toleran

|0.01 mg protein |1 mg wet weight

...ure (thyroid), very toxic to aquatic life, very toxic to aquatic life with long-lasting effects ::::# Weigh 32.6 mg of KCN.

:::: Hardware and software developments are based on long-term expertise with [[polarographic oxygen sensor]]s (POS) [1] and continuo ...ted (<0.5 mill cultured cells, 1-2 mg of fresh tissue from biopsies; <0.05 mg of mitochondrial protein), ''(3)'' pathological effects result in reduced r

...emonstrates the importance of PGC-1β for oxidative muscle integrity during long-term exposure to a myotoxic agent.

...e tri- and di-glycerides resulting in the release of free fatty acids. The long-chain, fatty acids get oxidized and activate UCP1, which thereby initiates

...dose of 7.5 Gy/day for 5 days in their tongues. Rats were treated with 45 mg/day melatonin or vehicle during 21 days post-irradiation, either by local a Considering the low toxicity of melatonin even during long term, which makes possible its clinical use, our results provide evidence f

...tion]] in conjunction with the [[Q-Module]], since the naturally occurring long-chain coenzyme Q (e.g. CoQ₁₀) is trapped within membrane boundar ::::# Dissolve one commercial vial of CoQ₂ (2 mg) in 628 µL ethanol abs.

|authors=White Sarah Haverty, Latham CM, Long CR, Randel RD, Welsh TH ...ry. Data were analyzed using the MIXED procedure of SAS (9.4). Relative to mg tissue (integrative), the LD from temperamental heifers had greater mitocho

...ogen): C3737 (Calcium Green™-5N, Hexapotassium Salt, cell impermeant); 0.5 mg vial, store at -20°C. ::::# Dissolve the complete vial of CaG (0.5 mg) in 419 µL of deionized H₂O.

...elevated arterial lactate (2.8 mmol/L, IQR, 2-4), C-reactive protein (220 mg/L, IQR, 119-284), and capillary refill time (5.5 s, IQR, 3-8). Respiratory ...ided an earlier recognition of septic shock patients in the ICU at risk of long-term deterioration of health status.

...be determined as a measure of amount of mitochondria or mt-concentration [mg mt-protein/mL]. However, protein cannot be used as a mt-biomarker in other ...al 2011). Expressing structure by functional markers is without problem as long as the structure in question does not undergo any functional (qualitative)

...control or high-fat chow for 21 wk and treated with a single low dose (20 mg/kg) of streptozotocin at week 4 High-fat and streptozotocin treatment induc

...ly, cynomolgus macaques (''Macaca fascicularis'') are well suited to model long-term dietary changes [1]. Similar to humans, these animals exhibit similar ...erred to a wash buffer for 15 minutes on ice. Samples of approximately 2.5 mg (wet weight) are selected and analyzed in the Oroboros O2k using two protoc

...ersistent damage in an organ-specific manner. DMF partially prevents these long-term mitochondrial changes in myocardium and brain. ...n of spontaneous circulation (ROSC). Next, animals received either DMF (30 mg/kg) or vehicle (Placebo) daily for four days. Sham animals underwent identi

...ution of mitochondria to 0.02 mg/mL protein concentration. Dilution of 0.1 mg mitochondrial protein in a 2-mL chamber yields an optimum concentration for ::::* Protein contamination and other macroscopic deposits: After long-term use, a whitish deposit can form on the glass walls of the O2k-Chamber.

...n with Martin's team to study and train the Alaskan dogs in preparation of long-distance races, the most challenging of which is the 1,100 mile Iditarod ra ...rtin incorporates sprint-dog lines and is selected and trained as much for long-distance endurance as for speed - and happiness. "Happy dogs perform better

...onse to autophagic modulation. Treatments were carried out using the U-118 MG (ATCC HTB15(TM)) human glioma cell line cultured in Dulbecco's Modified Eag ...neda FJ, Hardwick JM (2008) Mitochondrial fission and fusion dynamics: the long and short of it. Cell Death Differ 15:1147-52.

...species, matrix cyclophilin D, Pi, and matrix pH. When PTP opening becomes long-lasting, it causes collapse of the proton gradient preventing ATP synthesis ...annel forms after a conformational change that would follow replacement of Mg²⁺ with Ca²⁺ at the catalytic sites located in the β

...f 10 to 20 kPa, rather than at physiological 0.5 to 3 kPa. This is fine as long as a concentration-independent saturating concentration range is obtained, ...to artificial diffusion gradients resulting from the spatial constraints (long diffusion distances) in the fiber preparation ([[Gnaiger 2003 Adv Exp Med B

...''_''m'',X = ''J''_''V'',X/(mg/mL) | Units: [pmol/(s·mg)] ...'_''V'',X - ''J''_''V'',0)/(mg/mL) | Units: [pmol/(s·mg)]

...tract=After overcoming COVID-19, some people develop a variety of mid- and long-term effects like fatigue, breathlessness, cognitive dysfunction as part of

...alibration-SOP (Version 18)]]: Prepare "zero solution" by dissolving c. 20 mg sodium hydrosulfite ([[OroboPOS-Service Kit]]) or two tips of a spatula in ...0 and 30 mM. Due to the oxidation process that occurs when Dit is open for long time, we recommend to use a concentration of 30 mM for performing the instr

It has long been believed that TCS is harmless to mammals, since they do not have the E ...tar rats by differential centrifugation. The swelling of mitochondria (0.4 mg/mL) was measured as a decrease in A₅₄₀ in a stirred cuvette at r

...otic organisms are scarce: these drugs were introduced into practice not a long time ago and in quite a hasty manner [2]. The available literature data ind ...ria) at 25 °C under continuous stirring. The swelling of mitochondria (0.4 mg/mL) was measured as a decrease in A₅₄₀ in a stirred cuvette at r

...plex® UltraRed''' from Life Technologies (former Invitrogen): A36006; 5* 1 mg commercial vials, store at -20°C. ...10 mM storage solution is stable for 6 months. We have observed that after long-term storage AmR may exert a profound inhibitory effect on cell respiration

...öger and Klingenberg [22]. Interactions occur by collisional processes and long-lived intermediates are not readily observed, since electron transfer is ra ::::* cytochrome ''bc''₁ content of around 0.2 nmol per mg protein [26]

...asuring neuronal cells - everything looks perfect! I should have bought it long time ago.'' '''[[Galkin A| Galkin Alexander]]''', Queen's University Belfas ...me Resolution]. I reduced the mitochondrial concentration (from 0.5 to 0.3 mg protein/ml ) and I´ve reduced the data recording interval to the minimum

...aiger 2012) have made it possible to reduce the amount of tissue to ca. 10 mg based on a needle biopsy with local anesthesia. Respiratory diagnostic prot ...project outputs, including a summary for the future strategy, to ensure a long-term impact of the project activities.

...in isolated mitochondria (threshold: 121±60 vs. 40±10 nmol Ca²⁺/mg protein in WG and Sol)''". ::::'''1.''' Lai N, M Kummitha C, Rosca MG, Fujioka H, Tandler B, Hoppel CL (2019) Isolation of mitochondrial subpopul

:::# Lai N, M Kummitha C, Rosca MG, Fujioka H, Tandler B, Hoppel CL (2018) Isolation of mitochondrial subpopul ...ham O, Shearwood AM, Mercer TR, Davies SM, Mattick JS, Filipovska A (2011) Long noncoding RNAs are generated from the mitochondrial genome and regulated by

...Abumrad NA, Acuna-Castroviejo D, Adiele RC, Ahn B, Ali SS, Alton L, Alves MG, Amati F, Amoedo ND, Andreadou I, Arago M, Aragones J, Aral C, Arandarcikai ...as become established despite deficiencies of accuracy and meaning. In the long run, superior standards will become accepted. We hope to contribute to this

|'''"1 mg/L treatment [of microplastics] resulted in a decrease in hepatic mitochondr :::: '''»[[Long Night of Research 2022 Innsbruck AT]]«'''

:::# Lai N, M Kummitha C, Rosca MG, Fujioka H, Tandler B, Hoppel CL (2018) Isolation of mitochondrial subpopul ...ham O, Shearwood AM, Mercer TR, Davies SM, Mattick JS, Filipovska A (2011) Long noncoding RNAs are generated from the mitochondrial genome and regulated by

:::: '''1.23. Ref 67''' Gammon ST, Pisaneschi F, Bandi ML, Smith MG, Sun Y, Rao Y, Muller F, Wong F, De Groot J, Ackroyd J, Mawlawi O, Davies M :::: '''1.30. Ref 74''' Jaramillo-Jimenez A, Giil LM, Borda MG, Tovar-Rios DA, Kristiansen KA, Bruheim P, Aarsland D, Barreto GE, Berge RK