Semantic search
From Bioblast
Year | Reference | Coupling | Pathway | Preparation | Organism | Tissue;cell | |
---|---|---|---|---|---|---|---|
Evinova 2020 J Membr Biol | 2020 | Evinova A, Cizmarova B, Hatokova Z, Racay P (2020) High‑resolution respirometry in assessment of mitochondrial function in neuroblastoma SH‑SY5Y intact cells. J Membr Biol 253:129-36. | LEAK ROUTINE ET | N S ROX | Permeabilized cells Intact cells | Human | Neuroblastoma |
Bloise 2020 Thyroid | 2020 | Bloise FF, Santos AT, Brito JT, Andrade CBV, Oliveira TS, Souza AF, Fontes KN, Silva JD, Blanco NG, Silva PL, Rocco PRM, Fliers E, Boelen A, da-Silva WS, Ortiga-Carvalho TM (2020) Sepsis impairs thyroid hormone signaling and mitochondrial function in the mouse diaphragm. Thyroid 30:1079-90. | LEAK OXPHOS ET | N CIV NS | Permeabilized tissue | Mouse | Skeletal muscle |
Catalan-Garcia 2020 J Clin Med | 2020 | Catalán-García M, García-García FJ, Moreno-Lozano PJ, Alcarraz-Vizán G, Tort-Merino A, Milisenda JC, Cantó-Santos J, Barcos-Rodríguez T, Cardellach F, Lladó A, Novials A, Garrabou G, Grau-Junyent JM (2020) Mitochondrial dysfunction: A common hallmark underlying comorbidity between sIBM and other degenerative and age-related diseases. J Clin Med 9:E1446. | LEAK ET | Permeabilized cells | Human | Fibroblast | |
Pelster 2020 PLoS One | 2020 | Pelster B, Wood CM, Campos DF, Val AL (2020) Cellular oxygen consumption, ROS production and ROS defense in two different size-classes of an Amazonian obligate air-breathing fish (Arapaima gigas). PLoS One 15:e0236507. | LEAK OXPHOS ET | N S CIV NS ROX | Permeabilized tissue | Fishes | Kidney Lung;gill |
E-L coupling efficiency | 2020 | Gnaiger E (2020) Biochemical coupling efficiency: from 0 to <1. Mitochondr Physiol Network (2015-01-18) last update 2020-11-12. | LEAK ET | ||||
McCann 2020 Metabolites | 2020 | McCann MR, McHugh CE, Kirby M, Jennaro TS, Jones AE, Stringer KA, Puskarich MA (2020) A multivariate metabolomics method for estimating platelet mitochondrial oxygen consumption rates in patients with sepsis. Metabolites 10:E139. | LEAK ROUTINE ET | ROX | Intact cells | Human | Platelet |
Truong 2020 Cytokine | 2020 | Truong NTT, Lydic TA, Bazil JN, Suryadevara A, Olson LK (2020) Regulation of lipid metabolism in pancreatic beta cells by interferon gamma: a link to anti-viral function. Cytokine 133:155147. | LEAK ROUTINE ET | Intact cells | Rat | Islet cell;pancreas;thymus | |
Chang 2020 J Biol Chem | 2020 | Chang L, Liu X, Diggle CP, Boyle JP, Hopkins PM, Shaw MA, Allen PD (2020) Bioenergetic defects in muscle fibers of RYR1 mutant knock-in mice associated with malignant hyperthermia. J Biol Chem 295:15226-35. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
Thome 2020 JCI Insight | 2020 | Thome T, Kumar RA, Burke SK, Khattri RB, Salyers ZR, Kelley RC, Coleman MD, Christou DD, Hepple RT, Scali ST, Ferreira LF, Ryan TE (2020) Impaired muscle mitochondrial energetics is associated with uremic metabolite accumulation in chronic kidney disease. JCI Insight 6:e139826. | LEAK OXPHOS | F N S | Isolated mitochondria | Mouse | Skeletal muscle |
Ramos 2020 PLoS One | 2020 | Ramos SV, Hughes MC, Delfinis LJ, Bellissimo CA, Perry CGR (2020) Mitochondrial bioenergetic dysfunction in the D2.mdx model of Duchenne muscular dystrophy is associated with microtubule disorganization in skeletal muscle. https://doi.org/10.1371/journal.pone.0237138 | LEAK OXPHOS | N NS | Permeabilized tissue | Mouse | Skeletal muscle |
Schneider 2020 PLoS One | 2020 | Schneider J, Han WH, Matthew R, Sauve Y, Lemieux H (2020) Age and sex as confounding factors in the relationship between cardiac mitochondrial function and type 2 diabetes in the Nile Grass rat. PLoS One 15:e0228710. | LEAK OXPHOS | F N S CIV NS ROX | Permeabilized tissue | Rat | Heart |
Fuller 2020 J Appl Physiol (1985) | 2020 | Fuller KNZ, McCoin CS, Allen J, Bell-Glenn S, Koestler DC, Dorn Ii GW, Thyfault JP (2020) Sex and BNIP3 genotype, rather than acute lipid injection, modulate hepatic mitochondrial function and steatosis risk in mice. J Appl Physiol (1985) 128:1251-61. | LEAK OXPHOS ET | F N NS | Isolated mitochondria | Mouse | Liver |
Severo 2020 Life Sci | 2020 | Severo L, Godinho D, Machado F, Hartmann D, Fighera MR, Soares FA, Furian AF, Oliveira MS, Royes LF (2020) The role of mitochondrial bioenergetics and oxidative stress in depressive behavior in recurrent concussion model in mice. Life Sci 257:117991. | LEAK OXPHOS ET | N S NS ROX | Homogenate | Mouse | Nervous system |
Weaver 2020 Biol Lett | 2020 | Weaver RJ, Carrion G, Nix R, Maeda GP, Rabinowitz S, Iverson ENK, Thueson K, Havird JC (2020) High mitochondrial mutation rates in Silene are associated with nuclear-mediated changes in mitochondrial physiology. Biol Lett 16:20200450. | LEAK OXPHOS | N S CIV NS | Isolated mitochondria | Plants | |
Roginski 2020 Biochim Biophys Acta Mol Basis Dis | 2020 | Roginski AC, Wajner A, Cecatto C, Wajner SM, Castilho RF, Wajner M, Amaral AU (2020) Disturbance of bioenergetics and calcium homeostasis provoked by metabolites accumulating in propionic acidemia in heart mitochondria of developing rats. Biochim Biophys Acta Mol Basis Dis 1866:165682. | LEAK OXPHOS ET | N S NS | Permeabilized cells Isolated mitochondria Homogenate | Rat | Heart Other cell lines |
Vulczak 2020 Cells | 2020 | Vulczak A, Souza AO, Ferrari GD, Azzolini AECS, Pereira-da-Silva G, Alberici LC (2020) Moderate exercise modulates tumor metabolism of triple-negative breast cancer. Cells 9:E628. | LEAK OXPHOS ET | N ROX | Permeabilized cells | Mouse | Endothelial;epithelial;mesothelial cell |
Sowton 2020 Mol Genet Metab Rep | 2020 | Sowton AP, Padmanabhan N, Tunster SJ, McNally BD, Murgia A, Yusuf A, Griffin JL, Murray AJ, Watson ED (2020) Mtrr hypomorphic mutation alters liver morphology, metabolism and fuel storage in mice. Mol Genet Metab Rep 23:100580. | LEAK OXPHOS | N NS | Homogenate | Mouse | Liver |
Karabatsiakis 2020 Transl Psychiatry | 2020 | Karabatsiakis DA, Schönfeldt-Lecuona PDC (2020) Depression, mitochondrial bioenergetics, and electroconvulsive therapy: a new approach towards personalized medicine in psychiatric treatment - a short review and current perspective. Transl Psychiatry 10:226. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells |
Gruenig 2020 Biochem Pharmacol | 2020 | Grünig D, Szabo L, Marbet M, Krähenbühl S (2020) Valproic acid affects fatty acid and triglyceride metabolism in HepaRG cells exposed to fatty acids by different mechanisms. Biochem Pharmacol 177:113860. | LEAK OXPHOS ET | N S DQ CIV ROX | Isolated mitochondria | Mouse | Liver |
Allen 2020 Commun Biol | 2020 | Allen ME, Pennington ER, Perry JB, Dadoo S, Makrecka-Kuka M, Dambrova M, Moukdar F, Patel HD, Han X, Kidd GK, Benson EK, Raisch TB, Poelzing S, Brown DA, Shaikh SR (2020) The cardiolipin-binding peptide elamipretide mitigates fragmentation of cristae networks following cardiac ischemia reperfusion in rats. Commun Biol 3:389. | LEAK OXPHOS ET | N S CIV | Permeabilized tissue | Rat | Heart |
Garcia 2020 Mol Hum Reprod | 2020 | Garcia BM, Machado TS, Carvalho KF, Nolasco P, Nociti RP, Del Collado M, Capo Bianco MJD, Grejo MP, Neto JDA, Sugiyama FHC, Tostes K, Pandey AK, Gonçalves LM, Perecin F, Meirelles FV, Ferraz JBS, Vanzela EC, Boschero AC, Guimarães FEG, Abdulkader F, Laurindo FRM, Kowaltowski AJ, Chiaratti MR (2020) Mice born to females with oocyte-specific deletion of mitofusin 2 have increased weight gain and impaired glucose homeostasis. Mol Hum Reprod 26:938-52. | LEAK OXPHOS ET | S | Isolated mitochondria | Mouse | Liver |
Duong 2020 Mitochondrion | 2020 | Duong QV, Hoffman A, Zhong K, Dessinger MJ, Zhang Y, Bazil JN (2020) Calcium overload decreases net free radical emission in cardiac mitochondria. Mitochondrion 51:126-39. | LEAK OXPHOS ET | F N S | Isolated mitochondria | Guinea pig | Heart |
Burgin 2020 Int J Mol Sci | 2020 | Burgin HJ, Lopez Sanchez MIG, Smith CM, Trounce IA, McKenzie M (2020) Pioglitazone and deoxyribonucleoside combination treatment increases mitochondrial respiratory capacity in m.3243A>G MELAS cybrid cells. Int J Mol Sci 21:E2139. | LEAK ROUTINE ET | ROX | Intact cells | Human | Other cell lines |
Fecker 2020 Biomolecules | 2020 | Fecker R, Buda V, Alexa E, Avram S, Pavel IZ, Muntean D, Cocan I, Watz C, Minda D, Dehelean CA, Soica C, Danciu C (2020) Phytochemical and biological screening of Oenothera biennis L. hydroalcoholic extract. Biomolecules 10:E818. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | Endothelial;epithelial;mesothelial cell |
Guo 2020 Hum Gene Ther | 2020 | Guo Y, Zhang K, Gao X, Zhou Z, Liu Z, Yang K, Huang K, Yang Q, Long Q (2020) Sustained oligomycin sensitivity conferring protein expression in cardiomyocytes protects against cardiac hypertrophy induced by pressure-overload via improving mitochondrial function. Hum Gene Ther 31:1178-89. | LEAK OXPHOS ET | N NS ROX | Isolated mitochondria | Mouse | Heart |
Herpich 2020 Exp Gerontol | 2020 | Herpich C, Franz K, Klaus S, Müller-Werdan U, Ost M, Norman K (2020) Age-related fatigue is associated with reduced mitochondrial function in peripheral blood mononuclear cells. Exp Gerontol 144:111177. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells |
Alston 2020 Am J Hum Genet | 2020 | Alston CL, Veling MT, Heidler J, Taylor LS, Alaimo JT, Sung AY, He L, Hopton S, Broomfield A, Pavaine J, Diaz J, Leon E, Wolf P, McFarland R, Prokisch H, Wortmann SB, Bonnen PE, Wittig I, Pagliarini DJ, Taylor RW (2020) Pathogenic bi-allelic mutations in NDUFAF8 cause Leigh syndrome with an isolated complex I deficiency. Am J Hum Genet 106:92-101. | LEAK ROUTINE OXPHOS ET | N NS | Permeabilized cells Intact cells | Human | Fibroblast |
Romeiro 2020 bioRxiv | 2020 | Romeiro NC, Ferreira CM, Oliveira MF (2020) Assessment of mitochondrial physiology of murine white adipose tissue by mechanical permeabilization and lipid depletion. bioRxiv doi: https://doi.org/10.1101/2020.02.19.956870. | LEAK OXPHOS ET | S ROX | Permeabilized tissue | Mouse | Fat |
Politis-Barber 2020 Am J Physiol Endocrinol Metab | 2020 | Politis-Barber V, Brunetta HS, Paglialunga S, Petrick HL, Holloway GP (2020) Long-term high-fat feeding exacerbates short-term increases in adipose mitochondrial reactive oxygen species, without impairing mitochondrial respiration. Am J Physiol Endocrinol Metab 319:E376-87. | LEAK OXPHOS | F N Gp NS | Permeabilized cells | Mouse | Fat |
Russell 2020 Nutrients | 2020 | Russell JS, Griffith TA, Naghipour S, Vider J, Du Toit EF, Patel HH, Peart JN, Headrick JP (2020) Dietary α-linolenic acid counters cardioprotective dysfunction in diabetic mice: unconventional PUFA protection. Nutrients 12:E2679. | LEAK OXPHOS ET | N S NS | Homogenate | Mouse | Heart |
Groennebaek 2020 Cells | 2020 | Groennebaek T, Billeskov TB, Schytz CT, Jespersen NR, Bøtker HE, Olsen RKJ, Eldrup N, Nielsen J, Farup J, De Paoli FV, Vissing K (2020) Mitochondrial structure and function in the metabolic myopathy accompanying patients with critical limb ischemia. Cells 9:E570. | LEAK OXPHOS | N NS ROX | Permeabilized tissue | Human | Skeletal muscle |
MitoEAGLE blood cells 1 | 2020 | Åsander Frostner Eleonor*, Aburel Oana M*, Avram Vlad F*, Calabria Elisa, Castelo Rueda Maria Paulina*, Chamkha Imen*, Čižmárová Beata, Danila Maria-Daniela*, Doerrier Carolina*, Eckert Gunter P*, Ehinger Johannes K, Elmer Eskil*, Garcia-Souza Luiz F*, Gnaiger Erich*, Hoppel Florian*, Karabatsiakis Alexander*, Keppner Gloria, Kidere Dita*, Krako Jakovljević Nina, Labieniec-Watala Magdalena*, Lelcu Theia*, Micankova Petra, Michalak Slawomir*, Molina Anthony JA*, Pavlovic Kasja, Pichler Irene*, Piel Sarah, Rousar Tomas, Rybacka-Mossakowska Joanna, Schartner Melanie, Siewiera Karolina*, Silaidos Carmina*, Sjövall Fredrik*, Sobotka Ondrej*, Sumbalova Zuzana*, Swiniuch Daria, Vernerova Andrea*, Volani Chiara*, Vujacic-Mirski Ksenija*, Watala Cezary* (2020) Interlaboratory guide to mitochondrial respiratory studies with peripheral blood mononuclear cells and platelets. - Updated: 2020-03-06 - *Confirmed | LEAK ROUTINE OXPHOS ET | F N S Gp CIV NS Other combinations ROX | Intact cells Permeabilized cells | Human | Blood cells Platelet |
Hassan 2020 MitoFit Preprint Arch | 2020 | Hassan Hazirah, Gnaiger Erich, Zakaria Fazaine, Makpol Suzana, Abdul Karim Norwahidah (2020) Alterations in mitochondrial respiratory capacity and membrane potential: a link between mitochondrial dysregulation and autism. https://doi.org/10.26124/mitofit:200003 | LEAK OXPHOS ET | N S CIV NS ROX | Permeabilized cells | Human | |
Gutierrez 2020 Sci Signal | 2020 | Gutiérrez T, Qi H, Yap MC, Tahbaz N, Milburn LA, Lucchinetti E, Lou PH, Zaugg M, LaPointe PG, Mercier P, Overduin M, Bischof H, Burgstaller S, Malli R, Ballanyi K, Shuai J, Simmen T (2020) The ER chaperone calnexin controls mitochondrial positioning and respiration . Sci Signal 13:eaax6660. | LEAK ROUTINE ET | Intact cells | Mouse | Fibroblast | |
Gumpp 2020 Proc Natl Acad Sci U S A | 2020 | Gumpp AM, Boeck C, Behnke A, Bach AM, Ramo-Fernández L, Welz T, Gündel H, Kolassa IT, Karabatsiakis A (2020) Childhood maltreatment is associated with changes in mitochondrial bioenergetics in maternal, but not in neonatal immune cells. Proc Natl Acad Sci U S A 117:24778-84. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells |
Jian 2020 Cell Metab | 2020 | Jian C, Fu J, Cheng X, Shen LJ, Ji YX, Wang X, Pan S, Tian H, Tian S, Liao R, Song K, Wang HP, Zhang X, Wang Y, Huang Z, She ZG, Zhang XJ, Zhu L, Li H (2020) Low-dose sorafenib acts as a mitochondrial uncoupler and ameliorates nonalcoholic steatohepatitis. Cell Metab 31:892-908. https://doi.org/10.1016/j.cmet.2020.04.011 | LEAK OXPHOS ET | N S CIV ROX | Permeabilized cells | Mouse | Liver |
Cruz 2020 Cancers (Basel) | 2020 | Cruz B, Oliveira A, Viana LR, Lopes-Aguiar L, Canevarolo R, Colombera MC, Valentim RR, Garcia-Fóssa F, de Sousa LM, Castelucci BG, Consonni SR, Martins-de-Souza D, de Jesus MB, Russell ST, Gomes-Mardondes MCC (2020) Leucine-tich diet modulates the metabolomic and proteomic profile of skeletal muscle during cancer cachexia. Cancers (Basel) 12:E1880. | LEAK ROUTINE ET | Intact cells | Mouse | Skeletal muscle | |
Lensu 2020 Nutrients | 2020 | Lensu S, Pariyani R, Mäkinen E, Yang B, Saleem W, Munukka E, Lehti M, Driuchina A, Lindén J, Tiirola M, Lahti L, Pekkala S (2020) Prebiotic xylo-oligosaccharides ameliorate high-fat-diet-induced hepatic steatosis in rats . Nutrients 12:E3225. | LEAK OXPHOS ET | N S NS ROX | Homogenate | Rat | Liver |
Kawamura 2021 Mol Ther Nucleic Acids | 2020 | Kawamura E, Maruyama M, Abe J, Sudo A, Takeda A, Takada S, Yokota T, Kinugawa S, Harashima H, Yamada Y (2021) Validation of gene therapy for mutant mitochondria by delivering mitochondrial RNA using a MITO-porter. Mol Ther Nucleic Acids 20:687-98. | LEAK OXPHOS | Permeabilized cells | Human | Fibroblast | |
Ledur 2020 Sci Rep | 2020 | Ledur PF, Karmirian K, Pedrosa CDSG, Souza LRQ, Assis-de-Lemos G, Martins TM, Ferreira JCCG, de Azevedo Reis GF, Silva ES, Silva D, Salerno JA, Ornelas IM, Devalle S, Madeiro da Costa RF, Goto-Silva L, Higa LM, Melo A, Tanuri A, Chimelli L, Murata MM, Garcez PP, Filippi-Chiela EC, Galina A, Borges HL, Rehen SK (2020) Zika virus infection leads to mitochondrial failure, oxidative stress and DNA damage in human iPSC-derived astrocytes. Sci Rep 10:1218. | LEAK ROUTINE ET | ROX | Intact cells | Human | Nervous system |
Tichanek 2020 Sci Rep | 2020 | Tichanek F, Salomova M, Jedlicka J, Kuncova J, Pitule P, Macanova T, Petrankova Z, Tuma Z, Cendelin J (2020) Hippocampal mitochondrial dysfunction and psychiatric-relevant behavioral deficits in spinocerebellar ataxia 1 mouse model. Sci Rep 10:5418. | LEAK OXPHOS ET | N S CIV NS ROX | Homogenate | Mouse | Nervous system |
Heinonen 2020 Sci Rep | 2020 | Heinonen I, Sorop O, van Dalen BM, Wüst RCI, van de Wouw J, de Beer VJ, Octavia Y, van Duin RWB, Hoogstrate Y, Blonden L, Alkio M, Anttila K, Stubbs A, van der Velden J, Merkus D, Duncker DJ (2020) Cellular, mitochondrial and molecular alterations associate with early left ventricular diastolic dysfunction in a porcine model of diabetic metabolic derangement. Sci Rep 10:13173. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Pig | Heart |
Piel 2020 FEBS J | 2020 | Piel MS, Masscheleyn S, Bouillaud F, Moncoq K, Miroux B (2020) Structural models of mitochondrial uncoupling proteins obtained in DPC micelles are not functionally relevant. FEBS J 288:3024-33. | LEAK OXPHOS ET | Permeabilized cells | Saccharomyces cerevisiae | ||
Szibor 2020 J Cell Mol Med | 2020 | Szibor M, Schreckenberg R, Gizatullina Z, Dufour E, Wiesnet M, Dhandapani PK, Debska-Vielhaber G, Heidler J, Wittig I, Nyman TA, Gaertner U, Hall AR, Pell V, Viscomi C, Krieg T, Murphy MP, Braun T, Gellerich FN, Schlueter KD, Jacobs HT(2020) Respiratory chain signalling is essential for adaptive remodelling following cardiac ischaemia. J Cell Mol Med 24:3534-48. | LEAK OXPHOS | N S CIV | Permeabilized tissue Isolated mitochondria | Mouse | Heart |
Piel 2020 PLoS One | 2020 | Piel S, Chamkha I, Dehlin AK, Ehinger JK, Sjövall F, Elmér E, Hansson MJ (2020) Cell-permeable succinate prodrugs rescue mitochondrial respiration in cellular models of acute acetaminophen overdose. PLoS One 15:e0231173. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | Liver Platelet |
Dolezelova 2020 PLoS Biol | 2020 | Doleželová E, Kunzová M, Dejung M, Levin M, Panicucci B, Regnault C, Janzen CJ, Barrett MP, Butter F, Zíková A (2020) Cell-based and multi-omics profiling reveals dynamic metabolic repurposing of mitochondria to drive developmental progression of Trypanosoma brucei. PLoS Biol 18:e3000741. | LEAK ROUTINE | S Gp CIV | Permeabilized cells Intact cells | Protists | |
Assis-de-Lemos 2020 Curr Protoc Toxicol | 2020 | Assis-de-Lemos G, Ledur PF, Karmirian K, Rehen SK, Galina A (2020) A protocol to study mitochondrial function in human neural progenitors and iPSC-derived astrocytes. Curr Protoc Toxicol 85:e97. | LEAK ROUTINE ET | ROX | Intact cells | Human | Nervous system |
Plecita-Hlavata 2020 Antioxid Redox Signal | 2020 | Plecitá-Hlavatá L, Engstová H, Holendová B, Tauber J, Špaček T, Petrásková L, Křen V, Špačková J, Gotvaldová K, Ježek J, Dlasková A, Smolková K, Ježek P (2020) Mitochondrial superoxide production decreases on glucose-stimulated insulin secretion in pancreatic β cells due to decreasing mitochondrial matrix NADH/NAD+ ratio. Antioxid Redox Signal 33:789-815. | LEAK ROUTINE ET | ROX | Intact cells | Rat | Islet cell;pancreas;thymus |
Dirks 2020 J Physiol | 2020 | Dirks ML, Miotto PM, Goossens GH, Senden JM, Petrick HL, van Kranenburg J, van Loon LJC, Holloway GP (2020) Short-term bed rest-induced insulin resistance cannot be explained by increased mitochondrial H2O2 emission. J Physiol 598:123-37. | LEAK OXPHOS | N NS | Permeabilized tissue | Human | Skeletal muscle |
Bertero 2020 Circ Res | 2020 | Bertero E, O'Rourke B, Maack C (2020) Mitochondria do not survive calcium overload during transplantation. Circ Res 126:784-86. | LEAK OXPHOS | N | Isolated mitochondria | Mouse | Skeletal muscle |
Krabbendam 2020 Cell Death Dis | 2020 | Krabbendam IE, Honrath B, Dilberger B, Iannetti EF, Branicky RS, Meyer T, Evers B, Dekker FJ, Koopman WJH, Beyrath J, Bano D, Schmidt M, Bakker BM, Hekimi S, Culmsee C, Eckert GP, Dolga AM (2020) SK channel-mediated metabolic escape to glycolysis inhibits ferroptosis and supports stress resistance in C. elegans. Cell Death Dis 11:263. | LEAK OXPHOS | N S | Isolated mitochondria | Mouse | Nervous system |
Irion 2020 Stem Cells Int | 2020 | Irion CI, Martins EL, Christie MLA, de Andrade CBV, de Moraes ACN, Ferreira RP, Pimentel CF, Suhett GD, Campos de Carvalho AC, Lindoso RS, Vieyra A, Galina A, Goldenberg RCS (2020) Acute myocardial infarction reduces respiration in rat cardiac fibers, despite adipose tissue mesenchymal stromal cell transplant. Stem Cells Int 2020:4327965 . | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Rat | Heart |
Song 2020 Obes Facts | 2020 | Song K, Zhang Y, Ga Q, Bai Z, Ge RL (2020) Increased insulin sensitivity by high-altitude hypoxia in mice with high-fat diet-induced obesity is associated with activated AMPK signaling and subsequently enhanced mitochondrial biogenesis in skeletal muscles. Obes Facts 13:455-72. | LEAK OXPHOS | F N | Permeabilized tissue | Skeletal muscle | |
Mann 2020 Sci Rep | 2020 | Mann J, Yang N, Montpetit R, Kirschenman R, Lemieux H, Goping IS (2020) BAD sensitizes breast cancer cells to docetaxel with increased mitotic arrest and necroptosis. https://doi.org/10.1038/s41598-019-57282-1 | LEAK ROUTINE ET | Intact cells | Human | Other cell lines | |
Wefers 2020 Mol Metab | 2020 | Wefers J, Connell NJ, Fealy CE, Andriessen C, de Wit V, van Moorsel D, Moonen-Kornips E, Jörgensen JA, Hesselink MKC, Havekes B, Hoeks J, Schrauwen P (2020) Day-night rhythm of skeletal muscle metabolism is disturbed in older, metabolically compromised individuals. Mol Metab 41:101050. | LEAK OXPHOS ET | F N NS | Permeabilized tissue | Human | Skeletal muscle |
Kamarauskaite 2020 Biomed Res Int | 2020 | Kamarauskaite J, Baniene R, Trumbeckas D, Strazdauskas A, Trumbeckaite S (2020) Increased succinate accumulation induces ROS generation in in vivo ischemia/reperfusion-affected rat kidney mitochondria. Biomed Res Int 2020:8855585. | LEAK OXPHOS | N S | Rat | Kidney | |
Al-Azab 2020 FEBS J | 2020 | Al-Azab M, Qaed E, Ouyang X, Elkhider A, Walana W, Li H, Li W, Tang Y, Adlat S, Wei J, Wang B, Li X (2020) TL1A/TNFR2-mediated mitochondrial dysfunction of fibroblast-like synoviocytes increases inflammatory response in patients with rheumatoid arthritis via reactive oxygen species generation. FEBS J 287:3088-104. | LEAK ROUTINE OXPHOS ET | N ROX | Permeabilized cells Intact cells | Human | Other cell lines |
Ayari 2020 Commun Biol | 2020 | Ayari Asma, Rosa-Calatrava Manuel, Lancel Steve, Barthelemy Johanna, Pizzorno Andres, Mayeuf-Louchart Alicia, Baron Morgane, Hot David, Deruyter Lucie, Soulard Daphnee, Julien Thomas, Faveeuw Christelle, Molendi-Coste Olivier, Dombrowicz David, Sedano Laura, Sencio Valentin, Le Goffic Ronan, Trottein Francois, Wolowczuk Isabelle (2020) Influenza infection rewires energy metabolism and induces browning features in adipose cells and tissues. Commun Biol 3:237. | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Fat |
Marrocco 2020 Thesis | 2020 | Marrocco A (2020) Alterations of CCSP expression and macrophages metabolism in the development of silica-induced pulmonary inflammation and fibrosis. PhD Thesis 108. | LEAK OXPHOS ET | S ROX | Intact cells | Mouse | Macrophage-derived |
Anand 2020 Toxicol In Vitro | 2020 | Anand CR, Bhavya B, Jayakumar K, Harikrishnan VS, Gopala S (2020) Inorganic nitrite alters mitochondrial dynamics without overt changes in cell death and mitochondrial respiration in cardiomyoblasts under hyperglycemia. Toxicol In Vitro 70:105048. | LEAK ROUTINE ET | ROX | Intact cells | Rat | Heart |
Pena 2020 Int J Chronic Dis | 2020 | Pena GS, Paez HG, Johnson TK, Halle JL, Carzoli JP, Visavadiya NP, Zourdos MC, Whitehurst MA, Khamoui AV (2020) Hippocampal growth factor and myokine cathepsin B expression following aerobic and resistance training in 3xTg-AD mice. Int J Chronic Dis 2020:Article ID 5919501. | LEAK OXPHOS ET | N S NS ROX | Homogenate | Mouse | Nervous system |
Luevano-Martinez 2020 FEBS Lett | 2020 | Luévano-Martínez LA, Girard RMBM, Alencar MB, Silber AM (2020) ATP regulates the activity of an alternative oxidase in Trypanosoma brucei. FEBS Lett [Epub ahead of print]. | LEAK ROUTINE ET | Intact cells | Protists | ||
Magnesa 2020 Thesis | 2020 | Magnesa B (2020) Skeletal muscle mitochondrial oxidative phosphorylation plasticity in two studies on humans: exercise training effect in obese subjects and bed rest effect in healthy subjects. PhD Thesis 81. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Cipullo 2020 Nucleic Acids Res | 2020 | Cipullo M, Pearce SF, Lopez Sanchez IG, Gopalakrishna S, Krüger A, Schober F, Busch JD, Li X, Wredenberg A, Atanassov I, Rorbach J (2020) Human GTPBP5 is involved in the late stage of mitoribosome large subunit assembly. Nucleic Acids Res 49:354-70. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | HEK |
Frambach 2020 Biochim Biophys Acta Mol Basis Dis | 2020 | Frambach SJCM, van de Wal MAE, van den Broek PHH, Smeitink JAM, Russel FGM, de Haas R, Schirris TJJ (2020) Effects of clofibrate and KH176 on life span and motor function in mitochondrial complex I-deficient mice. Biochim Biophys Acta Mol Basis Dis 1866:165727. | LEAK OXPHOS | F N S Gp CIV Other combinations ROX | Permeabilized tissue | Mouse | Skeletal muscle |
Andrade 2020 Nutr Metab Cardiovasc Dis | 2020 | Andrade D, Oliveira G, Menezes L, Nascimento AL, Carvalho S, Stumbo AC, Thole A, Garcia-Souza É, Moura A, Carvalho L, Cortez E (2020) Insulin-like growth factor-1 short-period therapy improves cardiomyopathy stimulating cardiac progenitor cells survival in obese mice. Nutr Metab Cardiovasc Dis 30:151-61. | LEAK OXPHOS | F N NS | Permeabilized tissue | Mouse | Heart |
Kuzniewska 2020 EMBO Rep | 2020 | Kuzniewska B, Cysewski D, Wasilewski M, Sakowska P, Milek J, Kulinski TM, Winiarski M, Kozielewicz P, Knapska E, Dadlez M, Chacinska A, Dziembowski A, Dziembowska M (2020) Mitochondrial protein biogenesis in the synapse is supported by local translation. EMBO Rep 21:e48882. | LEAK ET | N S | Permeabilized cells | Human Mouse | Nervous system HEK |
Hingst 2020 Mol Metab | 2020 | Hingst JR, Kjøbsted R, Birk JB, Jørgensen NO, Larsen MR, Kido K, Larsen JK, Kjeldsen SAS, Fentz J, Frøsig C, Holm S, Fritzen AM, Dohlmann TL, Larsen S, Foretz M, Viollet B, Schjerling P, Overby P, Halling JF, Pilegaard H, Hellsten Y, Wojtaszewski JFP (2020) Inducible deletion of skeletal muscle AMPKα reveals that AMPK is required for nucleotide balance but dispensable for muscle glucose uptake and fat oxidation during exercise. Mol Metab 40:101028. | LEAK OXPHOS ET | N S NS | Permeabilized tissue | Mouse | Skeletal muscle |
Ferreira 2020 PLoS Genet | 2020 | Ferreira N, Andoniou CE, Perks KL, Ermer JA, Rudler DL, Rossetti G, Periyakaruppiah A, Wong JKY, Rackham O, Noakes PG, Degli-Esposti MA, Filipovska A (2020) Murine cytomegalovirus infection exacerbates complex IV deficiency in a model of mitochondrial disease. PLoS Genet 16:e1008604. | LEAK OXPHOS ET | N ROX | Isolated mitochondria | Mouse | Liver |
Reutzel 2020 Oxid Med Cell Longev | 2020 | Reutzel M, Grewal R, Dilberger B, Silaidos C, Joppe A, Eckert GP (2020) Cerebral mitochondrial function and cognitive performance during aging: A longitudinal study in NMRI mice. Oxid Med Cell Longev 2020:4060769. | LEAK ET OXPHOS | N S CIV ROX | Isolated mitochondria | Mouse | Nervous system |
Ajime 2020 Nicotine Tob Res | 2020 | Ajime TT, Serré J, Wüst RCI, Messa GAM, Poffé C, Swaminathan A, Maes K, Janssens W, Troosters T, Degens H, Gayan-Ramirez G (2020) Two weeks smoking cessation reverses cigarette smoke-induced skeletal muscle atrophy and mitochondrial dysfunction in mice. Nicotine Tob Res 23:143-51. | LEAK ET | S | Permeabilized tissue | Mouse | Skeletal muscle |
Yadav 2020 Cell Death Dis | 2020 | Yadav SK, Kambis TN, Kar S, Park SY, Mishra PK (2020) MMP9 mediates acute hyperglycemia-induced human cardiac stem cell death by upregulating apoptosis and pyroptosis in vitro. Cell Death Dis 11:186. | LEAK OXPHOS ET | N CIV NS ROX | Permeabilized cells | Human | Heart Stem cells |
Allen 2020 Thesis | 2020 | Allen FM (2020) Mitochondrial metabolism elucidated by rapid fractionation from tissue. PhD Thesis 298. | LEAK ET | S | Isolated mitochondria | Mouse Rat | Heart Liver |
Seo 2020 J Clin Med | 2020 | Seo DY, Heo JW, No MH, Yoo SZ, Ko JR, Park DH, Kang JH, Kim CJ, Jung SJ, Han J, Kwak HB (2020) Exercise training protects against atorvastatin-induced skeletal muscle dysfunction and mitochondrial dysfunction in the skeletal muscle of rats. J Clin Med 9:E2292. | LEAK OXPHOS | N | Permeabilized tissue | Rat | Skeletal muscle |
Risiglione 2020 Int J Mol Sci | 2020 | Risiglione P, Leggio L, Cubisino SAM, Reina S, Paternò G, Marchetti B, Magrì A, Iraci N, Messina A (2020) High-resolution respirometry reveals MPP+ mitochondrial toxicity mechanism in a cellular model of parkinson's disease. Int J Mol Sci 21:E7809. https://doi.org/10.3390/ijms21217809 | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | Neuroblastoma |
Shi 2020 Diabetes | 2020 | Shi JH, Lu JY, Chen HY, Wei CC, Xu X, Li H, Bai Q, Xia FZ, Lam SM, Zhang H, Shi YN, Cao D, Chen L, Shui G, Yang X, Lu Y, Chen YX, Zhang WJ (2020) Liver ChREBP protects against fructose-induced glycogenic hepatotoxicity by regulating L-type pyruvate kinase. Diabetes 120:29. | LEAK ROUTINE ET | Intact cells | Mouse | Liver | |
Ugarteburu 2020 J Clin Med | 2020 | Ugarteburu O, Sánchez-Vilés M, Ramos J, Barcos-Rodríguez T, Garrabou G, García-Villoria J, Ribes A, Tort F (2020) Physiopathological bases of the disease caused by HACE1 mutations: alterations in autophagy, mitophagy and oxidative stress response. J Clin Med 9:E913. | LEAK ROUTINE ET | ROX | Intact cells | Human | Fibroblast |
Pham 2020 Eur J Appl Physiol | 2020 | Pham T, MacRae CL, Broome SC, D'souza RF, Narang R, Wang HW, Mori TA, Hickey AJR, Mitchell CJ, Merry TL (2020) MitoQ and CoQ10 supplementation mildly suppresses skeletal muscle mitochondrial hydrogen peroxide levels without impacting mitochondrial function in middle-aged men. Eur J Appl Physiol 120:1657-69. | LEAK OXPHOS ET | N CIV NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Visavadiya 2020 Mol Cell Biochem | 2020 | Visavadiya NP, Pena GS, Khamoui AV (2020) Mitochondrial dynamics and quality control are altered in a hepatic cell culture model of cancer cachexia. Mol Cell Biochem 476:23-34. | LEAK OXPHOS ET | N S NS ROX | Permeabilized cells | Mouse | Liver |
Wen 2020 Biomedicines | 2020 | Wen JJ, Cummins CB, Williams TP, Radhakrishnan RS (2020) The genetic evidence of burn-induced cardiac mitochondrial metabolism dysfunction . Biomedicines 8:E566. | LEAK OXPHOS ET | N S NS | Permeabilized tissue | Rat | Heart |
Grewal 2020 Exp Neurol | 2020 | Grewal R, Reutzel M, Dilberger B, Hein H, Zotzel J, Marx S, Tretzel J, Sarafeddinov A, Fuchs C, Eckert GP (2020) Purified oleocanthal and ligstroside protect against mitochondrial dysfunction in models of early Alzheimer's disease and brain ageing. Exp Neurol 328:113248. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Intact cells | Human | Neuroblastoma |
Boel 2020 J Exp Biol | 2020 | Boël M, Romestaing C, Duchamp C, Veyrunes F, Renaud S, Roussel D, Voituron Y (2020) Improved mitochondrial coupling as a response to high mass-specific metabolic rate in extremely small mammals. J Exp Biol 223:jeb215558. | LEAK ET | N NS | Permeabilized tissue | Mouse | Skeletal muscle |
Falcao-Tebas 2020 J Physiol | 2020 | Falcão-Tebas F, Marin EC, Kuang J, Bishop DJ, McConell GK (2020) Maternal exercise attenuates the lower skeletal muscle glucose uptake and insulin secretion caused by paternal obesity in female adult rat offspring. J Physiol 598:4251-70. | LEAK OXPHOS ET | N NS ROX | Permeabilized tissue | Rat | Skeletal muscle |
Simard 2020 Metabolites | 2020 | Simard C, Lebel A, Allain EP, Touaibia M, Hebert-Chatelain E, Pichaud N (2020) Metabolic characterization and consequences of mitochondrial pyruvate carrier deficiency in Drosophila melanogaster. Metabolites 109:E363. | LEAK OXPHOS ET | N S Gp NS ROX | Permeabilized tissue | Drosophila | |
Esselun 2020 Neuromolecular Med | 2020 | Esselun C, Dilberger B, Silaidos CV, Koch E, Schebb NH, Eckert GP (2020) A walnut diet in combination with enriched environment improves cognitive function and affects lipid metabolites in brain and liver of aged NMRI mice. Neuromolecular Med 23:140-60. | LEAK OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Mouse | Nervous system |
Cruz 2020 Drug Alcohol Depend | 2020 | Cruz JV, Maba IK, Correia D, Kaziuk FD, Cadena SMSC, Zampronio AR (2020) Intermittent binge-like ethanol exposure during adolescence attenuates the febrile response by reducing brown adipose tissue thermogenesis in rats. Drug Alcohol Depend 209:107904. | LEAK OXPHOS | N | Isolated mitochondria | Rat | Fat |
Juarez-Flores 2020 Antioxidants (Basel) | 2020 | Juarez-Flores DL, Ezquerra M, Gonzalez-Casacuberta I, Ormazabal A, Moren C, Tolosa E, Fucho R, Guitart-Mampel M, Casado M, Valldeoriola F, de la Torre-Lara J, Munoz E, Tobias E, Compta Y, Garcia-Garcia FJ, Garcia-Ruiz C, Fernandez-Checa JC, Marti MJ, Grau JM, Cardellach F, Artuch R, Fernandez-Santiago R, Garrabou G (2020) Disrupted mitochondrial and metabolic plasticity underlie comorbidity between age-related and degenerative disorders as Parkinson disease and type 2 diabetes mellitus. Antioxidants (Basel) 9:1063. | LEAK ROUTINE ET | ROX | Permeabilized cells Intact cells | Human | Fibroblast |
Macedo 2020 FASEB J | 2020 | Macedo F, Romanatto T, Gomes de Assis C, Buis A, Kowaltowski AJ, Aguilaniu H, Marques da Cunha F (2020) Lifespan-extending interventions enhance lipid-supported mitochondrial respiration in Caenorhabditis elegans. FASEB J 34:9972-81. | LEAK OXPHOS | F N CIV ROX | Intact organism Isolated mitochondria | Caenorhabditis elegans | |
Avila-Rojas 2020 Food Chem Toxicol | 2020 | Avila-Rojas SH, Aparicio-Trejo OE, Briones-Herrera A, Medina-Campos ON, Reyes-Fermín LM, Martínez-Klimova E, León-Contreras JC, Hernández-Pando R, Tapia E, Pedraza-Chaverri J (2020) Alterations in mitochondrial homeostasis in a potassium dichromate model of acute kidney injury and their mitigation by curcumin. Food Chem Toxicol 145:111774. | LEAK OXPHOS ET | N S NS ROX | Isolated mitochondria | Rat | Kidney |
Stepanova 2020 Methods Cell Biol | 2020 | Stepanova A, Galkin A (2020) Measurement of mitochondrial H2O2 production under varying O2 tensions. https://doi.org/10.1016/bs.mcb.2019.12.008 | LEAK OXPHOS | S N Gp | Isolated mitochondria | Mouse | Nervous system |
De Souza 2020 Heliyon | 2020 | De Souza CEA, Andrade Pires AR, Cardoso CR, Carlos RM, Cadena SMSC, Acco A (2020) Antineoplastic activity of a novel ruthenium complex against human hepatocellular carcinoma (HepG2) and human cervical adenocarcinoma (HeLa) cells. Heliyon 6:e03862. | LEAK ROUTINE ET | ROX | Intact cells | Human | Liver HeLa |
Davidson 2020 Circ Res | 2020 | Davidson MT, Grimsrud P, Lai L, Draper J, Fisher-Wellman KH, Narowski TM, Koves TR, Kelly DP, Muoio DM (2020) Extreme acetylation of the cardiac mitochondrial proteome does not promote heart failure. Circ Res 127:1094-108. | LEAK | F N | Isolated mitochondria | Mouse | Heart |
Dymkowska 2020 J Appl Toxicol | 2020 | Dymkowska D, Wrzosek A, Zabłocki K (2020) Atorvastatin and pravastatin stimulate nitric oxide and reactive oxygen species generation, affect mitochondrial network architecture and elevate nicotinamide N-methyltransferase level in endothelial cells. J Appl Toxicol 41:1076-88. | LEAK ET ROUTINE | Intact cells | Human | Endothelial;epithelial;mesothelial cell | |
Lara-Marqueza 2020 J Funct Foods | 2020 | Lara-Márquez M, Báez-Magaña M, Raymundo-Ramos C, Spagnuolo PA, Macías-Rodríguez L, Salgado-Garciglia R, Ochoa-Zarzosa A, López-Meza JE (2020) Lipid-rich extract from Mexican avocado (Persea americana var. drymifolia) induces apoptosis and modulates the inflammatory response in Caco-2 human colon cancer cells. J Funct Foods 64:103658. | LEAK ROUTINE ET | Intact cells | Human | Endothelial;epithelial;mesothelial cell | |
Hayes 2020 Nutrients | 2020 | Hayes P, Fergus C, Ghanim M, Cirzi C, Burtnyak L, McGrenaghan CJ, Tuorto F, Nolan DP, Kelly VP (2020) Queuine micronutrient deficiency promotes Warburg metabolism and reversal of the mitochondrial ATP synthase in HeLa cells. Nutrients 12:E871. | LEAK ROUTINE OXPHOS ET | N S Gp CIV ROX | Permeabilized cells Intact cells | Human | HeLa |
Beninca 2020 J Med Genet | 2020 | Beninca C, Zanette V, Brischigliaro M, Johnson M, Reyes A, Valle DAD, Robinson AJ, Degiorgi A, Yeates A, Telles BA, Prudent J, Baruffini E, Santos ML, de Souza RL, Fernandez-Vizarra E, Whitworth A, Zeviani M (2020) Mutation in the MICOS subunit gene APOO (MIC26) associated with an X-linked recessive mitochondrial myopathy, lactic acidosis, cognitive impairment and autistic features. J Med Genet 58:155-67. | LEAK ROUTINE ET | Intact cells | Human | Fibroblast | |
Larsen 2020 Cardiovasc Drugs Ther | 2020 | Larsen AH, Wiggers H, Dollerup OL, Jespersen NR, Hansson NH, Frøkiær J, Brøsen K, Nørrelund H, Bøtker HE, Møller N, Jessen N (2020) Metformin lowers body weight but fails to increase insulin sensitivity in chronic heart failure patients without diabetes: a randomized, double-blind, placebo-controlled study. Cardiovasc Drugs Ther 35:491-503. | LEAK OXPHOS ET | N NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Kupats 2020 Oxid Med Cell Longev | 2020 | Kupats E, Stelfa G, Zvejniece B, Grinberga S, Vavers E, Makrecka-Kuka M, Svalbe B, Zvejniece L, Dambrova M (2020) Mitochondrial-protective effects of R-phenibut after experimental traumatic brain injury. Oxid Med Cell Longev 2020:9364598. | LEAK OXPHOS ET | N S NS | Homogenate Isolated mitochondria | Mouse | Nervous system |
Ehrlicher 2020 FASEB J | 2020 | Ehrlicher SE, Stierwalt HD, Miller BF, Newsom SA, Robinson MM (2020) Mitochondrial adaptations to exercise do not require Bcl2-mediated autophagy but occur with BNIP3/Parkin activation. FASEB J 34:4602-18. | LEAK OXPHOS ET | F N S NS | Isolated mitochondria | Mouse | Skeletal muscle |
Jaber 2020 BM Exp Neurol | 2020 | Jaber SM, Yadava N, Polster BM (2020) Mapping mitochondrial respiratory chain deficiencies by respirometry: beyond the Mito Stress Test. BM Exp Neurol 328:113282. | LEAK ROUTINE ET | ROX | Intact cells | Nervous system |