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  • Adenylate nucleotide translocase
    #REDIRECT [[Adenine nucleotide translocase]]
    44 bytes (4 words) - 19:27, 9 May 2017
  • Adenine nucleotide translocase
    |description=The '''adenine nucleotide translocator''', ANT, exchanges [[ADP]] for [[ATP]] in an electrogenic anti
    552 bytes (66 words) - 16:52, 20 July 2016
  • Adenine nucleotide translocator
    #REDIRECT [[Adenine nucleotide translocase]]
    44 bytes (4 words) - 20:01, 23 October 2010
  • O2k-Publications: Adenine nucleotide translocase
    ...ry:Publications]] [[Instrument and method::Oxygraph-2k]] [[Enzyme::Adenine nucleotide translocase]] ...egory:Abstracts]] [[Instrument and method::Oxygraph-2k]] [[Enzyme::Adenine nucleotide translocase]]
    1 KB (183 words) - 11:38, 11 November 2016

Page text matches

  • Danielson 1963 Biochem Z
    ...nt reduction of triphosphopyridine nucleotide by reduced diphosphopyridine nucleotide, coupled to the energy-transfer system of the respiratory chain. Biochem Z |keywords=Triphosphopyridine nucleotide, Diphosphopyridine nucleotide, Energy-transfer, Respiratory chain
    570 bytes (63 words) - 11:40, 28 May 2015
  • Klingenberg 1959 Biochem Z
    |title=Klingenberg M, Slenczka W (1959) Pyridine nucleotide in liver mitochondria. An analysis of their redox relationships. Biochem Z |keywords=Pyridine nucleotide
    422 bytes (53 words) - 10:36, 28 May 2015
  • Chance 1961 J Biol Chem-IV
    ...tive point are involved in succinate-linked reduction of pyridine nucleotide. ...dine nucleotide interaction observed in the oxidation of pyridine nucleotide in phosphorylating mitochondria is also part of the electron tran
    2 KB (258 words) - 09:54, 9 November 2016
  • Adenylate nucleotide translocase
    #REDIRECT [[Adenine nucleotide translocase]]
    44 bytes (4 words) - 19:27, 9 May 2017
  • ANT
    #REDIRECT [[Adenine nucleotide translocase]]
    44 bytes (4 words) - 14:47, 24 April 2012
  • Lee 1964 Biochim Biophys Acta
    ...ilibrium studies of the energy-dependent and non-energy-dependent pyridine nucleotide transhydrogenase reactions. Biochim Biophys Acta 81:187-90. |keywords=Pyridine nucleotide transhydrogenase
    471 bytes (52 words) - 12:03, 28 May 2015
  • Chance 1961 J Biol Chem-I
    ...rties and nature of the products of succinate-linked reduction of pyridine nucleotide. J Biol Chem 236:1534-43. ...ctivity in succinate oxidation passes through the diphosphopyridine nucleotide-linked pathway.
    3 KB (323 words) - 12:06, 8 November 2016
  • DPNH
    reduced Di-Phosphopyridine Nucleotide, former name of [[NADH]], reduced Nicotinamide Adenine Dinucleotide.
    106 bytes (11 words) - 12:56, 18 December 2013
  • Chance 1962 Science
    ...a tenfold difference in oxygen tension. Half-maximal increase in pyridine nucleotide reduction on the brain occurs at a concentration of inspired oxygen of abou
    2 KB (261 words) - 09:46, 3 May 2022
  • Klingenberg 1960 Biochem Z
    ...phosphate-dependent respiratory control and reduction of diphosphopyridine nucleotide in mitochondria. Biochem Z 333:335-51. |keywords=Oxidative phosphorylation, ATP, Diphosphopyridine nucleotide
    651 bytes (73 words) - 17:21, 16 January 2021
  • Chance 1961 J Biol Chem-III
    ...ransfer reactions in mitochondria III. Substrate requirements for pyridine nucleotide reduction in mitochondria. J Biol Chem 236:1555-61. ...uccinate requirement for energy-linked reduction of mitochondrial pyridine nucleotide is demonstrated in pigeon heart and guinea pig kidney mitochondria.
    2 KB (210 words) - 10:45, 6 July 2022
  • Ali 2023 Trends Cell Biol
    |title=Ali ES, Ben-Sahra I (2023) Regulation of nucleotide metabolism in cancers and immune disorders. Trends Cell Biol 33:950-66. htt ...we examine the mechanisms by which these signaling networks affect de novo nucleotide synthesis in mammalian cells. We also discuss how these molecular links can
    1 KB (201 words) - 08:10, 24 October 2023
  • Hoejeberg 1977 Biochem Biophys Res Commun
    ...ification and molecular properties of reconstitutively active nicotinamide nucleotide transhydrogenase from beef heart mitochondria. Biochem Biophys Res Commun 7 |abstract=Nicotinamide nucleotide transhydrogenase from beef heart mitochondria was purified to homogeneity a
    1 KB (148 words) - 12:45, 24 February 2015
  • Rydstroem 1975 Biochem Biophys Res Commun
    ...acker E (1975) Resolution and reconstitution of mitochondrial nicotinamide nucleotide transhydrogenase. Biochem Biophys Res Commun 67:831-9. |abstract=Nicotinamide nucleotide transhydrogenase from bovine heart mitochondria was solubilized with cholat
    1 KB (163 words) - 09:54, 27 November 2015
  • Chance 1961 J Biol Chem-VI
    ...t of entry of adenosine 5’-triphosphate may be at the pyridine nucleotide-flavin couple, but the entry of adenosine 5’-triphosphate simult |keywords=ATP, Pyridine nucleotide, Cytochrome oxidation, Electron transfer, Energy efficiency
    2 KB (259 words) - 09:54, 9 November 2016
  • Tufi 2014 Nat Cell Biol
    ...P, Abramov AY, Willis AE, Mallucci GR, Loh SH, Martins LM (2014) Enhancing nucleotide metabolism protects against mitochondrial dysfunction and neurodegeneration ...e mitochondrial biogenesis. We propose that targeting strategies enhancing nucleotide synthesis pathways may reverse mitochondrial dysfunction and rescue neurode
    2 KB (279 words) - 10:30, 8 November 2016
  • Guillet 2010 neurogenetics
    ...cio V, Amati-Bonneau P, Bonneau D, Reynier P, Chevrollier A (2010) Adenine nucleotide translocase is involved in a mitochondrial coupling defect in ''MFN2''-rela ...investigate mitochondrial oxygen consumption and the expression of adenine nucleotide translocase (ANT) and uncoupling proteins from eight other patients with th
    2 KB (237 words) - 12:38, 16 February 2018
  • Yakovlev 2007 Biochemistry
    ...state. Consequently, we derive kinetic and thermodynamic information about nucleotide binding and interconversion in complex I, relevant to understanding the mec
    2 KB (281 words) - 09:18, 22 October 2023
  • Konrad 2012 PLoS One
    ...itochondrial permeability transition but presence of bongkrekate-sensitive nucleotide exchange in ''C. crangon'' and ''P. serratus''. PLoS One 7:e39839. ...duced mitochondrial permeability transition and the sensitivity of adenine nucleotide translocase to bongkrekate are not necessarily related phenomena.
    2 KB (321 words) - 13:20, 10 March 2020
  • Estabrook 1962 Anal Biochem
    |title=Estabrook RW (1962) Fluorometric measurement of reduced pyridine nucleotide in cellular and subcellular particles . Anal Biochem 4:231-45.
    345 bytes (40 words) - 17:04, 16 February 2022
  • Lehninger 1949 J Biol Chem
    ...c phosphate coupled to electron transport between dihydrodiphosphopyridine nucleotide and oxygen II. J Biol Chem 178:625-44.
    373 bytes (46 words) - 13:44, 27 May 2015
  • Guillet 2010 Neurogenetics
    ...cio V, Amati-Bonneau P, Bonneau D, Reynier P, Chevrollier A (2010) Adenine nucleotide translocase is involved in a mitochondrial coupling defect in ''MFN2''-rela ...investigate mitochondrial oxygen consumption and the expression of adenine nucleotide translocase (ANT) and uncoupling proteins from eight other patients with th
    2 KB (235 words) - 12:38, 16 February 2018
  • Hogeboom 1950 J Biol Chem
    ...s of mammalian tissues III. Isocitric dehydrogenase and triphosphopyridine nucleotide-cytochrome c reductase of mouse liver. J Biol Chem 186:417-27.
    409 bytes (51 words) - 14:16, 27 May 2015
  • Friedkin 1949 J Biol Chem
    ...c phosphate coupled to electron transport between dihydrodiphosphopyridine nucleotide and oxygen. J Biol Chem 178:611-44. https://doi.org/10.1016/S0021-9258(18)5 ...show that inorganic phosphate is esterified when dihydrodiphosphopyridine nucleotide (DPNH2) is incubated aerobically with a particulate fraction of rat liver i
    1 KB (188 words) - 11:03, 8 October 2023
  • Bongkrekik acid
    ...'''Bongkrekik acid''' is a selective and potent inhibitor of the [[adenine nucleotide translocator]] (ANT). Bka binds to the matrix (negative) site of ANT, oppos
    366 bytes (47 words) - 20:51, 23 August 2015
  • Kampjut 2019 Nature
    ...nd linkers between the membrane and the soluble domains and their roles in nucleotide exchange. These structures enable us to propose a revised mechanism for a c |additional=Proton-translocating transhydrogenase, nicotinamide nucleotide transhydrogenase, NNT
    2 KB (310 words) - 17:38, 20 January 2023
  • Chinopoulos 2009
    ...ng standard binding equations. The assay is designed such that the adenine nucleotide translocase (ANT) is the sole mediator of changes in [Mg<sup>2+</sup>] in t |keywords=Adenine nucleotide translocase, ANT, ATP-ADP exchange, Magnesium Green
    2 KB (295 words) - 11:52, 9 February 2022
  • Jezek 2010 Physiol Res
    ...it originated from the onset of fatty acid cycling mediated by the adenine nucleotide translocase (major contribution) and mitochondrial uncoupling protein(s) (m ...spholipase A<sub>2</sub>, Fatty acids, Uncoupling of mitochondria, Adenine nucleotide translocase, Defense against oxidative stress
    2 KB (297 words) - 15:25, 26 May 2015
  • Kiss 2014 FASEB J
    ...ratory inhibition, which is manifested in the forward operation of adenine nucleotide translocase. Finally, we show that reoxidation of the reducible substrates |keywords=Succinyl-CoA ligase, Adenine nucleotide translocase, DT-diaphorase, Reducing equivalent, Safranin
    2 KB (278 words) - 13:35, 2 August 2023
  • Konrad 2012 Abstract Bioblast
    ...itochondrial permeability transition but presence of bongkrekate-sensitive nucleotide exchange in ''C. crangon'' and ''P. serratus''. Mitochondr Physiol Network mitochondrial adenine nucleotide exchange, prompting the conjecture that
    4 KB (511 words) - 14:15, 7 March 2020
  • Atractyloside
    ...loside''' is an inhibitor of the [[Adenine nucleotide translocator|adenine nucleotide translocator (ANT)]]. It is an extremely toxic glycoside that inhibits oxid
    1 KB (199 words) - 12:47, 12 February 2021
  • Adenine nucleotide translocase
    |description=The '''adenine nucleotide translocator''', ANT, exchanges [[ADP]] for [[ATP]] in an electrogenic anti
    552 bytes (66 words) - 16:52, 20 July 2016
  • O2k-Publications: Adenine nucleotide translocase
    ...ry:Publications]] [[Instrument and method::Oxygraph-2k]] [[Enzyme::Adenine nucleotide translocase]] ...egory:Abstracts]] [[Instrument and method::Oxygraph-2k]] [[Enzyme::Adenine nucleotide translocase]]
    1 KB (183 words) - 11:38, 11 November 2016
  • Di Noia 2014 J Biol Chem
    ...5A36 genes of solute carrier family 25 encode two mitochondrial pyrimidine nucleotide transporters. J Biol Chem 289:33137-48. ...2, the gene encoding the well characterized yeast mitochondrial pyrimidine nucleotide carrier, were overcome by expressing SLC25A33 or SLC25A36 in these cells. T
    2 KB (335 words) - 16:42, 3 May 2024
  • US MI Mt Pleasant McKee E
    ...tochondrial DNA depletion disease, ovarian cancer metabolism, nicotinamide nucleotide transhydrogenase (NNT) and Type II diabetes
    721 bytes (97 words) - 11:41, 12 October 2021
  • Chinopoulos 2011 Methods Mol Biol
    |keywords=Adenine nucleotide translocase; Adenine nucleotide carrier; Systems biology |enzymes=Adenine nucleotide translocase, Complex V;ATP synthase
    2 KB (311 words) - 17:51, 22 February 2021
  • Baines 2020 Biochim Biophys Acta Bioenerg
    ...al permeability transition pore: Is it formed by the ATP synthase, adenine nucleotide translocators or both? https://doi.org/10.1016/j.bbabio.2020.148249
    615 bytes (72 words) - 14:59, 20 March 2023
  • Chinopoulos 2014 Methods Enzymol
    ...ctions but mitochondrial exchange of ATP with ADP catalyzed by the adenine nucleotide translocase. The rate of ATP appearing in the medium upon the addition of A |keywords=ADP–ATP exchange, Adenine nucleotide carrier, Adenine nucleotide translocase, Bioenergetics, Oxidative phosphorylation, Systems biology, Mag
    3 KB (420 words) - 11:49, 27 October 2023
  • O´Gorman 1997 FEBS Lett
    ...containing octameric mitochondrial creatine kinase, porin and the adenine nucleotide translocator, were reconstituted into malate loaded lipid vesicles. Dimeris |keywords=Adenine nucleotide translocator, Apoptosis, Creatine kinase, Cyclocreatine, Mitochondria, Perm
    2 KB (220 words) - 15:37, 15 June 2015
  • Lou 2007 Biochem J
    ...eals a novel allosteric activation of proton transport through the adenine nucleotide translocase and provides a promising starting point for designing safer unc
    2 KB (239 words) - 15:12, 13 November 2017
  • Chance 1962 J Biol Chem
    ...with a high degree of oxidation of mitochondrial reduced diphosphopyridine nucleotide, which occurs immediately on addition of adenosine diphosphate and is follo ...d on independent evidence for a compartmentation of mitochondrial pyridine nucleotide (approximately one-third available to DPN-linked substrates), it is propos
    2 KB (260 words) - 17:18, 9 November 2017
  • Metelkin 2009 FEBS J
    ...09) Modeling of ATP-ADP steady-state exchange rate mediated by the adenine nucleotide translocase in isolated mitochondria. FEBS J 276:6942-55. ...ional model for the ATP-ADP steady-state exchange rate mediated by adenine nucleotide translocase (ANT) versus mitochondrial membrane potential dependence in iso
    2 KB (267 words) - 11:06, 3 April 2022
  • Puchowicz 2004 Mitochondrion
    ...tudy approach is employed to highlight detection of defects in the adenine nucleotide translocator, the pyruvate dehydrogenase complex, fumarase, coenzyme Q func |keywords=Oxidative phosphorylation; Skeletal muscle mitochondria; Adenine nucleotide translocator; Pyruvate dehydrogenase complex; Uncoupling; Carnitine palmito
    2 KB (233 words) - 12:09, 9 December 2021
  • Kim 2010 Korean Diabetes J
    |title=Kim EH, Koh EH, Park JY, Lee KU (2010) Adenine nucleotide translocator as a regulator of mitochondrial function: implication in the p ...synthesized in the mitochondria is exchanged for cytosolic ADP by adenine nucleotide translocator (ANT) to provide a continuous supply of ADP to mitochondria. W
    2 KB (269 words) - 19:56, 9 November 2023
  • Favia 2021 Int J Mol Sci
    ...linked to each other in the mitochondria thanks to the enzyme nicotinamide nucleotide transhydrogenase (NNT) which, by utilizing the mitochondrial membrane poten ...ic fibrosis, glucose-6-phosphate dehydrogenase, mitochondria, nicotinamide nucleotide transhydrogenase
    2 KB (302 words) - 17:34, 22 February 2022
  • Smith 2020 J Biol Chem
    ...PD (2020) Flux through mitochondrial redox circuits linked to nicotinamide nucleotide transhydrogenase generates counterbalance changes in energy expenditure. J ...H by activation of mitochondrial membrane potential-dependent nicotinamide nucleotide transhydrogenase (NNT). The coupling of reductive stress-induced JH<sub>2</
    3 KB (420 words) - 18:13, 20 October 2021
  • Devin 1997 Biochim Biophys Acta
    ...nd decreased on one of the protonmotive force dissipating systems (adenine nucleotide translocator), even if the fluxes increased. ...on efficiency, Kinetic control, Ionic media, Cytochrome c oxidase, Adenine nucleotide translocator, Rat liver mitochondria
    2 KB (285 words) - 13:52, 15 January 2020
  • Davis 2021 J Appl Physiol
    ...skeletal muscle expression of putative mitochondrial leak pathways adenine nucleotide transporter 1 and uncoupling protein 3, both of which were correlated with |enzymes=Adenine nucleotide translocase, Complex I, Complex II;succinate dehydrogenase, Uncoupling prot
    2 KB (285 words) - 15:33, 13 July 2021
  • Gizatullina 2005 Biochim Biophys Acta
    ...Carboxyatractylate (CAT) and atractylate inhibit the mitochondrial adenine nucleotide translocator (ANT) and stimulate the opening of permeability transition por |keywords=Mitochondria, Permeability transition pore, Adenine nucleotide translocator, Carboxyatractyloside, Bongkrekic acid
    2 KB (301 words) - 15:07, 24 March 2015
  • Klingenberg 1982 Eur J Biochem
    |abstract=The temperature dependence of the adenine nucleotide exchange in mitochondria has been determined by employing a rapid mixing, q |enzymes=Adenine nucleotide translocase
    2 KB (319 words) - 16:47, 11 February 2015
  • Deschauer 2006 Mol Genet Metab
    ...nal allele. This mutation affects the same codon as a C to T transition of nucleotide 823, resulting in a H275Y mutation that was found in two families with HLRC
    2 KB (306 words) - 15:19, 20 November 2018
  • Jastroch 2010 Essays Biochemistry
    ...and correlates with metabolic rate. The inducible leak through the adenine nucleotide translocase (ANT) and uncoupling proteins (UCPs) can be activated by fatty ...ncoupling, reactive oxygen species, superoxide, basal proton leak, adenine nucleotide translocase, uncoupling protein, ucp, superoxide, brown adipose tissue, mit
    2 KB (339 words) - 16:43, 5 March 2019
  • Rajasekaran 2018 FASEB J
    ..., Felser A, Nuoffer JM, Dufour JF, St-Pierre MV (2018) The histidine triad nucleotide-binding protein 2 (HINT-2) positively regulates hepatocellular energy metab |abstract=The histidine triad nucleotide-binding protein 2 (HINT-2) is a mitochondrial adenosine phosphoramidase exp
    2 KB (336 words) - 14:26, 18 September 2018
  • Kamath 2014 J Biol Chem
    ..., Mitochondrial metabolism, Nucleoside/nucleotide biosynthesis, Nucleoside/nucleotide metabolism, Thymidine kinase 2
    2 KB (355 words) - 14:33, 12 October 2021
  • Jennings 1981 Circ Res
    ...gh energy phosphate production, utilization, and depletion, and of adenine nucleotide catabolism in total ischemia in vitro vs. severe ischemia in vivo. Circ Res ...ivo in that the pathways of energy production and depletion and of adenine nucleotide degradation
    3 KB (400 words) - 08:40, 16 June 2015
  • Nicotinamide adenine dinucleotide
    ...''Nicotinamide adenine dinucleotide''', NAD<sup>+</sup> and NADH (pyridine nucleotide coenzymes, NAD and NADP), is an oxidation-reduction coenzyme (redox cofacto ::::* DPNH, reduced diphosphopyridine nucleotide = NADH
    4 KB (477 words) - 10:41, 4 April 2024
  • Kaambre 2013 Front Physiol
    ...ux redirection in cancer cells. A main result obtained is that the adenine nucleotide translocator exhibits the highest control of respiration in human breast ca |enzymes=Adenine nucleotide translocase, Complex I, Complex II;succinate dehydrogenase, Complex III, Co
    2 KB (318 words) - 11:31, 28 April 2015
  • Friederich-Persson 2012 PLoS One
    ...ute knockdown of uncoupling protein-2 increases uncoupling via the adenine nucleotide transporter and decreases oxidative stress in diabetic kidneys. PLoS One 7: ...ndria uncoupling after siRNA towards UCP-2 is mediated through the adenine nucleotide transporter (ANT). The increased oxidative stress in the diabetic kidney, m
    3 KB (345 words) - 16:35, 7 November 2016
  • Gao 2022 Biochim Biophys Acta Bioenerg
    ...to conventional fatty acids, thus apparently via activation of the adenine nucleotide transporter-2. In brown adipose tissue mitochondria, the N-acyl amino acids |keywords=Adenine nucleotide transporter, Fatty acids, N-acyl amino acids, N-arachidonoyl-gly, N-oleoyl-
    3 KB (356 words) - 10:26, 5 December 2022
  • McManus 2019 Cell Metab
    ...ivity. Patients sharing the homozygous mutation (c.523delC) in the adenine nucleotide translocator 1 gene (SLC25A4, ANT1) develop cardiomyopathy that varies from |keywords=F(1)F(o)-ATPase, OPA1, Adenine nucleotide translocator, Aging, Cardiomyopathy, Complex I, Complex IV, Mitochondrial D
    2 KB (334 words) - 12:21, 3 April 2019
  • Smith 2013 J Physiol
    ...ZDF rats compared to lean controls, which coincided with decreased adenine nucleotide translocase 2 (ANT2) protein content. This decrease in submaximal ADP-stimu |enzymes=Adenine nucleotide translocase
    2 KB (339 words) - 09:12, 27 January 2020
  • Kiss 2012 Abstract Bioblast
    ...ic mice was attributed to a shift in the reversal potential of the adenine nucleotide translocase towards more negative values due to diminished matrix substrate ...ajda S, Vereczki V, Oh RJ, Adam-Vizi V (2010) Forward operation of adenine nucleotide translocase during F0F1-ATPase reversal: critical role of matrix substrate-
    5 KB (664 words) - 14:03, 16 June 2015
  • Chinopoulos 2010 FASEB J
    ...jda S, Vereczki V, Oh RJ, Adam-Vizi V (2010) Forward operation of adenine nucleotide translocase during F0F1-ATPase reversal: critical role of matrix substrate- ...potential can be more negative than the reversal potential of the adenine nucleotide translocase (ANT) but more positive than that of the F(0)F(1)-ATPase. Exper
    2 KB (330 words) - 10:53, 3 April 2022
  • Menze 2009 J Biol Chem
    ...ding the first 70 N-terminal amino acids of ''AfrLEA3m'' in-frame with the nucleotide sequence for green fluorescence protein. The chimeric protein was readily i
    2 KB (341 words) - 14:28, 28 March 2018
  • Palm 2013 Abstract MiP2013
    ...g the adenosine nucleotide transporter. Increased uncoupling via adenosine nucleotide transporter decreases mitochondrial membrane potential and kidney oxidative |enzymes=Adenine nucleotide translocase, Uncoupling protein
    4 KB (499 words) - 11:20, 28 April 2017
  • Ravasz 2017 Neurochem Int
    ...drial SLP was addressed by interrogating the directionality of the adenine nucleotide translocase during anoxia in isolated mouse brain and liver mitochondria. G |keywords=4-Aminobutyrate, Adenine nucleotide translocase, Aminooxyacetic acid, Anoxia, GHB, SSADH, Succinate, Vigabatrin
    3 KB (357 words) - 08:16, 28 March 2018
  • Gomez 2022 Nutrients
    ...ssociated with the high voltage-dependent anion channel (VDAC) and adenine nucleotide translocase 2 (ANT2), a possible reflection of the increased demand on phos |keywords=Adenine nucleotide translocase, Docosahexaenoic acid (DHA) deficiency, Membrane permeabilizati
    3 KB (344 words) - 13:27, 5 December 2022
  • Deng 2022 Cell Mol Life Sci
    ...B is essential for the maintenance of mitochondrial metabolism, especially nucleotide metabolism, demonstrating that LDHB is crucial for the survival and prolife ...ular plasticity, Lung cancer, Mitochondrial DNA, Mitochondrial metabolism, Nucleotide metabolism, Tumorigenicity
    3 KB (488 words) - 16:22, 3 August 2022
  • Pharaoh 2023 Geroscience
    ...sensitivity in aged mitochondria by increasing uptake through the adenine nucleotide translocator (ANT). https://doi.org/10.1007/s11357-023-00861-y |keywords=ATP production, Adenine nucleotide translocator (ANT), Adenosine diphosphate (ADP) sensitivity, Elamipretide o
    3 KB (370 words) - 09:58, 2 August 2023
  • Sharaf 2017 Biochim Biophys Acta
    ...e (mTRS) results from coordinated activities of complex I and nicotinamide nucleotide transhydrogenase. Biochim Biophys Acta 1858:955-65. ...energy states. Pharmacological inhibition of complex CI (CI), nicotinamide nucleotide transhydrogenase (NNT) and antioxidant system significantly decreased the a
    3 KB (390 words) - 06:29, 20 April 2020
  • Francisco 2018 J Neurochem
    ...co A, Ronchi JA, Navarro CDC, Figueira TR, Castilho RF (2018) Nicotinamide nucleotide transhydrogenase is required for brain mitochondrial redox balance under ha |abstract=Among mitochondrial NADP-reducing enzymes, nicotinamide nucleotide transhydrogenase (NNT) establishes an elevated matrix NADPH/NADP<sup>+</sup
    3 KB (405 words) - 13:20, 17 April 2019
  • O´Gorman 1996 Biochim Biophys Acta
    ...old increase in Mi-CK protein and a concomitant 3-fold increase in adenine nucleotide translocator (ANT) protein, when compared to control. In GPA-fed rats, the ...nic acid; Creatine; Mitochondrial inclusion body; Creatine kinase; Adenine nucleotide translocator; Metabolism; Oxidative phosphorylation; (Rat) Article Outline
    3 KB (364 words) - 14:08, 27 March 2015
  • Kiss 2013 FASEB J
    ...ic mice was attributed to a shift in the reversal potential of the adenine nucleotide translocase toward more negative values due to diminished matrix substrate- |keywords=Adenine nucleotide translocase; Reversal potential; Succinyl-CoA ligase, F<sub>0</sub>–F<sub
    3 KB (346 words) - 10:54, 3 April 2022
  • Schoenfeld 2004 Biochem J
    ...bition of the ADP/ATP carrier. Phytanic acid decreased the rate of adenine nucleotide exchange and increased the degree of control, which the ADP/ATP carrier has |enzymes=Adenine nucleotide translocase
    3 KB (381 words) - 11:04, 27 March 2018
  • Braun 2001 Biochim Biophys Acta
    ...-type counterpart was found, which implies increased permeability for that nucleotide across the mitochondrial outer membrane. In normal cardiac fibers 35% of th
    3 KB (387 words) - 10:54, 23 January 2019
  • Miotto 2016 Biochem J
    ...t ''in vivo'' activation of voltage-dependent anion channel (VDAC)/adenine nucleotide translocase (ANT) can support mitochondrial ADP transport. Altogether, we p |keywords=ADP sensitivity, Adenine nucleotide translocase, Exercise metabolism, Mitochondrial bioenergetics, Mitochondria
    3 KB (394 words) - 09:30, 8 November 2016
  • Walley 2009 Nat Rev Genet
    ...bvious question is how to improve the results obtained so far using single nucleotide polymorphism markers and how to move successfully into the other areas of g
    1 KB (178 words) - 22:09, 14 February 2020
  • Creatine kinase
    ...ane, hydrolyses ATP to ADP, which is directly transported to the [[adenine nucleotide translocase]] (ANT) for regulation of respiration and no release of ATP oc
    1 KB (182 words) - 12:24, 17 May 2016
  • Wallace 1988 Science
    ...thus providing a simple diagnostic test. This finding demonstrated that a nucleotide change in a mitochondrial DNA energy production gene can result in a neurol
    1 KB (160 words) - 16:19, 13 September 2023
  • Guerrero 2005 Am J Physiol Regul Integr Comp Physiol
    ...avanon O, Imbeaud S, Saks V, Pison C (2005) Functional coupling of adenine nucleotide translocase and mitochondrial creatine kinase is enhanced after exercise tr ...iration by creatine linked to a more efficient functional coupling adenine nucleotide translocase-mitochondrial creatine kinase, resulting in better exercise per
    3 KB (413 words) - 15:20, 26 March 2018
  • Chinopoulos C 2012 Abstract Bioblast
    ...e mitochondrial permeability transition in human cells lacking the adenine nucleotide translocase isoform 1. Mitochondr Physiol Network 17.12. ...ay also result in rupture of the outer membrane [1]. For long, the adenine nucleotide translocase ([[ANT]]) was suspected to be a structural component of the por
    4 KB (541 words) - 15:23, 9 November 2016
  • Holloway 2013 Abstract MiP2013
    ...ere lower (''P''<0.05) in ZDF rats, which coincided with decreased adenine nucleotide translocase 2 (ANT2) protein content. This decrease in submaximal ADP-stimu |enzymes=Adenine nucleotide translocase
    3 KB (414 words) - 15:15, 20 October 2017
  • Loew 1963 Biochim Biophys Acta
    |title=Loew H, Vallin I (1963) Succinate-linked diphosphopyridine nucleotide reduction in submitochondrial particles. Biochim Biophys Acta 69:361-4.
    1 KB (175 words) - 14:34, 24 November 2015
  • Guzun 2015 Acta Physiol (Oxf)
    ...tochondrial outer membrane (mtOM) which represents a bottleneck in adenine nucleotide and other energy metabolite transfer and micro-compartmentalization. Based |enzymes=Adenine nucleotide translocase, Inner mt-membrane transporter, Supercomplex
    3 KB (400 words) - 12:44, 16 February 2018
  • Sparks 2016 Diabetologia
    ...)-induced uncoupling, which is driven by the mitochondrial protein adenine nucleotide translocase 1 (ANT1). ...''p'' = 0.008). This difference disappeared in the presence of the adenine nucleotide translocator inhibitor carboxyatractyloside. Partial knockdown of ANT1 in C
    3 KB (422 words) - 16:10, 13 November 2017
  • Baines 2018 Cell Calcium
    |keywords=ATP synthase, Adenine nucleotide translocase, Bioenergetics, Cell death, Cyclophilin D, Cyclosporin A, Mitoc
    1 KB (196 words) - 19:43, 20 March 2023
  • Pasdois 2007 Am J Physiol Heart Circ Physiol
    ...and preserved half-saturation constant of respiration for ADP and adenine nucleotide translocase-mitochondrial creatine kinase coupling, respectively. Ouabain-i
    3 KB (436 words) - 12:42, 16 February 2018
  • McManus 2015 Abstract MiP2015
    ...somal recessive cardiomyopathy due a mutation in the mitochondrial adenine nucleotide translocator-1 (ANT1). Substantial variability in the progression of heart ...la J, Wallace DC (2013) Severity of cardiomyopathy associated with adenine nucleotide translocator-1 deficiency correlates with mtDNA haplogroup. Proc Natl Acad
    3 KB (415 words) - 15:59, 4 September 2015
  • Ruiz-Pesini 2004 Science
    ...bal human mitochondrial DNA (mtDNA) sequences permitted positioning of all nucleotide substitutions according to their order of occurrence. The relative frequenc
    1 KB (179 words) - 12:23, 26 February 2015
  • Schlattner 2018 MiPschool Tromso B1
    ...and its functional consequences beyond the simple maintenance of proper [[nucleotide]] pools: stimulation of respiration, “energy export”, and regulation of
    2 KB (187 words) - 22:22, 17 October 2018
  • Pruuchova 2022 Antioxidants (Basel)
    ...ids (FAs) for FA-dependent H<sup>+</sup> transport mediated by the adenine nucleotide translocase (ANT) or uncoupling protein 2 (UCP2). The resulting mild mitoch |keywords=Adenine nucleotide translocase, Cardiolipin remodeling, Mitochondria, Phospholipase iPLA2γ/PN
    3 KB (456 words) - 11:06, 5 December 2022
  • Hingst 2020 Mol Metab
    ...ucible deletion of skeletal muscle AMPKα reveals that AMPK is required for nucleotide balance but dispensable for muscle glucose uptake and fat oxidation during ...t mice reveals that AMPK is required for maintaining muscle ATP levels and nucleotide balance during exercise but is dispensable for regulating muscle glucose up
    3 KB (439 words) - 21:06, 24 September 2020
  • Chinopoulos 2011 J Neurosci Res
    ...ely depolarizing mitochondria, the F(0) -F(1) ATP synthase and the adenine nucleotide translocase (ANT) may change directionality independently from each other (
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    ...e outlined. It is found that absolute quantification of the total pyridine nucleotide pool from tissue is dependent on the assay method. NADH ED-FRAP has been sh
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    ...m in neurodegeneration. Both mitochondrial dysfunction and enhanced NLRP3 (nucleotide-binding oligomerization domain (NOD)-like receptor protein 3) inflammasome
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    ...d retinitis pigmentosa) or Leigh syndromes, especially a point mutation at nucleotide position 8993. M.8969G>A is a rare MT-ATP6 mutation, previously reported on
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    ...espiration was reduced in S females by silencing expression of the adenine nucleotide translocator (ANT), hydrogen peroxide generation was higher and the mRNA le
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    ...lthy, coupled, and energy-transforming mitochondria. Recently, the protein nucleotide-binding protein-like (NUBPL or IND1) was identified as an iron-sulfur clust
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    ...e specifically as the '''P»-system'''. The P»-system consists of [[adenine nucleotide translocase]], [[phosphate carrier]], and [[ATP synthase]]. Mitochondrial [
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    ...rats. The sequences of these insertions revealed that they contain single nucleotide polymorphisms identical to those present in mtDNA of the same animal. Inter
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    ...cytotoxic effect of paraquat and high-resolution respirometry, showed that nucleotide variant m.14597 A>G can be classified as pathogenic mutation.
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    ...played specific IMM defects: futile proton leak dependent upon the adenine nucleotide translocase and an increased sensitivity to the opening of the mitochondria
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    ...ntly reduce the regulated proton leak via uncoupling protein-2 and adenine nucleotide translocase. Inactin also contributes to increased mitochondrial hydrogen p
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    ...healthy, coupled, and energy-producing mitochondria. Recently, the protein nucleotide binding protein like (NUBPL or IND1) was identified as an iron-sulfur clust
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    ...influenced by changes in the concentration of ADP, stimulating the adenine nucleotide translocase and oxidative phosphorylation. Secondly, as a consequence of th
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    :::## The requirement for DPN and other nucleotide additions in the oxidative metabolism of tumors
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    ...uctive stress. Whether or not NADH shuttles and mitochondrial nicotinamide nucleotide transhydrogenase enzyme can regulate hypoxia-induced reductive stress is al
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    ...mitochondrial creatine kinase (MtCK), which functional coupling to adenine nucleotide translocase is enhanced by selective limitation of permeability of mitochon
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    ...cells and investigated whether CL or CL synthesis was required to support nucleotide synthesis in S-phase. HeLa cells were made quiescent by serum depletion for ...r, normal de novo CL biosynthesis or CL itself is not essential to support nucleotide synthesis during entry into S-phase of the human cell cycle.
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    ...ion. A model is proposed according to which complex I has two redox active nucleotide binding sites. One site (F) serves as an entry for the NADH oxidation and t
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    ...postanoxic impairments in structure and function of acinar cells, adenine nucleotide levels and the rates of phosphorylating and non-phosphorylating respiration
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    ...n-DNA interactions and is necessary for both accurate mitotic division and nucleotide excision repair. To demonstrate if complete loss of NRMT1 subsequently resu
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    ...ar BAT and rodent interscapular BAT. Human BAT was sensitive to the purine nucleotide GDP, providing the first direct evidence that human BAT mitochondria have t
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    ...tionally, mitochondria revealed highly coupled, as ATP synthase or adenine nucleotide translocator inhibition strongly impacted respiration. Finally, we determin
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    ...ion time is linked to the inactivation, specifically, of the mitochondrial nucleotide carrier, longevity is affected by other, and hitherto unknown, target(s) of
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    ...ould be long-chain acyl CoA esters that are known to inhibit the [[Adenine nucleotide translocase|ANT]] [3] from either side of the inner mitochondrial membrane. ...rner E, Shug AL, Elson C, Shrago E (1972) Reversible inhibition of adenine nucleotide translocation by long chain fatty acyl coenzyme A esters in liver mitochond
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    ...ths in aged rats led to a partial restoration of androgens, NO, and cyclic nucleotide levels, as well as the expression of steroidogenic and NO/cGMP signaling ge
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    ...hese isolated mitochondria by oxidised-reduced difference spectra. Adenine nucleotide translocase (ANT) was measured by titration of mitochondrial respiration wi
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    ...nderstood mechanisms, but includes the uncoupling proteins and the adenine nucleotide translocator (ANT). Beyond decreasing the efficiency of OXPHOS, proton leak
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    ...em, ATP synthesis at F1FO ATPase, substrate transporters including adenine nucleotide translocase and the phosphate-hydrogen co-transporter, and cation fluxes ac
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    ...he mitochondrial creatine kinase reaction was fully coupled to the adenine nucleotide translocator. Metabolites were released from mitochondrial fraction (MF) by
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    ...ts tight functional coupling to oxidative phosphorylation, via the adenine nucleotide translocase, can modulate mitochondrial permeability transition in the pres
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    ...e of non-phosphorylating preparations, especially with respect to pyridine nucleotide, flavoprotein, and cytochrome ''c''. In addition to cytochromes ''a''<sub>3
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    ...rs of the sodium–potassium ATPase ouabain and of the mitochondrial adenine nucleotide translocator atractyloside. This finding suggested an increased mitochondri
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    ...by actomyosin ATPase. The flux control coefficients of H+-ATPase, adenine-nucleotide translocase, phosphate transporter, NADH :ubiquinone oxidoreductase and cyt
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    ...mutations is regularly updated. In this study we describe the homoplasmic nucleotide substitution m.3472T>C in the MT-ND1 gene and specific changes in cell meta
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    ...tance of genome wide sequence variation? While much research exists on the nucleotide variation in the 1,000 Human Genomes, there are few quantitative measures o
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    ...g, but multiple lineages have undergone dramatic accelerations in rates of nucleotide substitution and extreme changes in mt genome structure. While molecular ev
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    ...cause of phosphocreatine hydrolysis and adenylate catabolism in the purine nucleotide cycle. At low ADP availability and suboptimal phosphate (less than 5 mM), a
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    ...es the maintenance of two highly divergent mtDNAs (F- and M-type, 8–40% of nucleotide divergence) associated with gametes, and occasionally coexisting in somatic
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    ...r system A: Complex I - 0.19, Complex III - 0.06, Complex IV 0.18, adenine nucleotide translocase (ANT) - 0.11, ATP synthase - 0.01, Pi carrier - 0.20, and the s
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    ...proteins, including carnitine-palmitoyl transferase-I (CPT-I) and adenine-nucleotide translocase have redox sensitive sites. Interestingly muscle contraction ha
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    ...independent of changes in fiber type composition. In conclusion, a single nucleotide mutation (R225Q) in the AMPK gamma3 subunit is associated with mitochondria
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    ...in the G1- and S-phase by exposure to the glucocorticoid dexamethasone and nucleotide analogue gemcitabine. At 30 % apoptosis, opposite effects were observed on
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    ...termembrane space mitochondrial creatine kinase connects VDAC with adenine nucleotide translocase and ATP synthase complex, on the cytoplasmic side VDAC is linke
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    ...sed by quercetin is lowered by increased [ADP] and is increased by adenine nucleotide transporter inhibitor, atractyloside, but not bongkrekic acid. Both quercet
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    ...g, but multiple lineages have undergone dramatic accelerations in rates of nucleotide substitution and extreme changes in mt genome structure. While molecular ev
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    ...MgATP reflects effective cycling of ATP and ADP between uMtCK and adenine nucleotide translocase (ANT). These results emphasize important role and various patho
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    |abstract=The hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are encoded by a family of four genes (HCN1-4). All is
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    ...proton (PMF) and potassium motive force (KMF), respiratory chain, adenine nucleotide translocator, Pi carrier, and K+/H+ exchanger (KHEmito) was able to simulat
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    ...n HEK293 cells without triggering reverse-mode action of CV or the adenine nucleotide translocase (ANT). Hyperpolarization was associated with low levels of CII-
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    ...CypD; parallel immunodetection revealed also the same contents of adenine nucleotide translocator or voltage-dependent anion channel. Increased resistance of fe
    3 KB (373 words) - 09:30, 8 November 2016
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    ...cluding redox signaling. Recent Advances: UCP2 structure, including purine nucleotide and fatty acid (FA) binding sites, strongly support the FA cycling mechanis
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    ...via specialized pathways mediated by CK and AK isoforms and direct adenine nucleotide channeling, these complexes do not exist in HL-1 cells due to less organize
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    ...cells complexes II and IV. Results obtained for the phosphate and adenine nucleotide carriers showed that in dN2a cells these carriers exerted lower control ove
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    ...t HK naturally bound to the outer mitochondrial membrane. When the adenine nucleotide transporter (ANT) was blocked by the carboxyatractiloside, the 3-BrPA effec
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    ...into both cytosolic and mitochondrial transfer RNA to generate a queuosine nucleotide at position 34 of the anticodon loop. The transfer RNA of primary tumors ha
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    .... One candidate is long-chain acyl CoA esters known to inhibit the adenine nucleotide translocator. Addition of oleoyl-CoA to post-diapause lysates markedly decr
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    ...drial integrity and is prevented by atractyloside, an inhibitor of adenine nucleotide translocator (ANT), suggesting that the regulatory mechanism occurs on the
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    ...ed by NADH were not affected by atractyloside, an inhibitor of the adenine nucleotide translocase, suggesting that these processes may not be ascribed to mitocho
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    ...troversial. A long-standing puzzle is that in permeabilized cells, adenine nucleotide translocase (ANT) is less accessible to cytosolic ADP than in isolated mito
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    ...iated with the function of both mitochondrial ATP synthase and the adenine nucleotide translocator, but not the phosphate carrier. Altogether, these data indicat
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    ...developed Silexoseqencing, a methodology to map the RNAse trail at single-nucleotide resolution, and identified ''in situ'' cleavage by Myg1 on specific transcr
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    ...t), submaximal ADP-stimulated respiration rates and the content of adenine nucleotide translocase 2 (ANT2) content were depressed compared to lean control animal
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    ...es transcription of a key NAD<sup>+</sup> biosynthetic enzyme nicotinamide nucleotide adenylyltransferase 1 (NMNAT1). NAD<sup>+</sup> repletion restores NAD<sup>
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    ...lexes. In addition, cerebellar glucocorticoid hormone receptor and adenine nucleotide translocase (ANT1) were downregulated at 128 dGA and 142 dGA, respectively.
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    ...Metabolic stress, as well as several antidiabetic agents, increase hepatic nucleotide monophosphate levels (NMP), activate AMP-activated protein kinase (AMPK), a
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    ...L). In order to estimate the mitochondrial proton leak through the adenine nucleotide translocator (ANT), atractyloside (25 µM) was also added. The protocol was
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    ...hosphate Dehydrogenase (H6PDH) is the only known generator of the pyridine nucleotide NADPH from NADP<sup>+</sup> in the Endoplasmic/Sarcoplasmic Reticulum (ER/S
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    ...abetes. This was confirmed in mice in which the heart-muscle-brain adenine nucleotide translocator isoform 1 (ANT1) was inactivated. ANT1-deficient animals are i
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    ...ctosome. The main rate-controlling steps in HBC are complex IV and adenine nucleotide transporter, but in HCC, complexes I and III. Our kinetic measurements conf
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    ...ondrial creatine kinase (miCK). However, ADP/ATP diffusion through adenine nucleotide translocase ([[ANT]]) and voltage-dependent anion carriers (VDACs) is also
    3 KB (407 words) - 14:46, 28 March 2018
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    ...during recovery from anoxia without affecting the restoration of cellular nucleotide triphosphates. Based on these data, it appears that oxidative phosphorylati
    3 KB (444 words) - 09:35, 9 November 2016
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    ...er experiments indicated that oligomycin cannot be replaced by the adenine nucleotide translocase inhibitors bongkrekic acid or carboxyatractyloside because, alt
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    3 KB (449 words) - 18:46, 1 January 2021
  • Phillips 2017 Cancer Res
    ...tes (65 increased and 20 decreased) clustered into the glycolytic pathway, nucleotide sugars, intermediates of the pentose phosphate pathway, and lipogenesis, in
    3 KB (388 words) - 22:31, 1 August 2018
  • Jumbo-Lucioni 2012 BMC Genomics
    ...ce, we performed genome-wide association mapping and identified 141 single nucleotide polymorphisms (SNPs) associated with differences in mitochondrial respirati
    3 KB (412 words) - 12:21, 9 August 2019
  • Yoval-Sanchez 2022 Redox Biol
    ...long NDUFV3 isoform can reach toward the FMN binding pocket and affect the nucleotide affinity to the apoenzyme. For the first time, we demonstrated a potential
    3 KB (440 words) - 12:07, 5 December 2022
  • Stincone 2014 Biol Rev Camb Philos Soc
    ...PP is important to maintain carbon homoeostasis, to provide precursors for nucleotide and amino acid biosynthesis, to provide reducing molecules for anabolism, a
    3 KB (429 words) - 16:15, 10 February 2022
  • Komlodi 2017 Neuropharmacology
    ...mitochondria, ATP produced by SLP can prevent the reversal of the adenine nucleotide translocase and thus the hydrolysis of glycolytic ATP. The aim of the prese
    3 KB (405 words) - 18:43, 16 January 2021
  • Hoppel 2018 MiPschool Tromso D2
    ...s due to a defect in Complex I, as well as in ATP synthase and the adenine nucleotide translocase. These defects are resolved with reperfusion. Subsequently, a
    3 KB (463 words) - 23:45, 25 January 2021
  • Kopinski 2019 Proc Natl Acad Sci U S A
    ...ample, increasing heteroplasmy levels of the mtDNA tRNA<sup>Leu(UUR)</sup> nucleotide (nt) 3243A > G mutation result successively in diabetes, neuromuscular dege
    3 KB (404 words) - 15:29, 15 October 2019
  • Horvath 2022 Antioxidants (Basel)
    ...itochondria energized with α-KG was decreased after inhibiting the adenine nucleotide translocase and Complex I (CI) in the transgenic strains compared to the co
    3 KB (448 words) - 15:57, 15 December 2022
  • Chouchani 2014 Nature
    ...te dehydrogenase, which in turn is driven by fumarate overflow from purine nucleotide breakdown and partial reversal of the malate/aspartate shuttle. After reper
    3 KB (424 words) - 21:37, 13 February 2022
  • McKee 2010 Abstract IOC60
    ...thymidine in the medium and was also the only mitochondrially synthesized nucleotide to freely equilibrate with the medium. The other mitochondrially synthesize
    3 KB (469 words) - 14:37, 8 November 2016
  • Bellissimo 2023 BEC
    |enzymes=Adenine nucleotide translocase
    4 KB (491 words) - 15:35, 31 July 2023
  • Visker 2024 Exp Physiol
    ...ng protein 3, peroxiredoxin-6, voltage-dependent anion channel and adenine nucleotide translocator 1 to provide further insight into mitochondrial function. ANOV
    3 KB (391 words) - 15:40, 10 January 2024
  • Pesta 2021 Front Endocrinol (Lausanne)
    ...us, Insulin sensitivity, Mitochondrial function, Physical activity, Single nucleotide polymorphism
    3 KB (406 words) - 14:07, 22 June 2022
  • Harper 2018 MiPschool Tromso E1
    ...UCP1 protein, and this is thought to occur through interfering with purine nucleotide inhibition of UCP1. When UCP1 is active, it allows protons to leak back int
    3 KB (502 words) - 12:14, 17 October 2018
  • Carboxyatractyloside
    ...yloside''' CAT is a highly selective and potent inhibitor of the [[adenine nucleotide translocator]] (ANT). CAT stabilizes the nucleoside binding site of ANT on
    3 KB (491 words) - 14:55, 7 February 2024
  • Piel 2015 Abstract MiPschool London 2015
    ...calcium, phosphate and oxidative stress while still suffering from adenine nucleotide depletion. This triggers MPTP opening through the mitochondrial matrix prot
    3 KB (423 words) - 09:10, 16 June 2015
  • Porter 2018 MiP2018b
    ...4% of maximal uncoupled respiration, P<0.001). The response to the adenine nucleotide translocase (ANT) inhibitor bongkrekic acid during state 4 respiration was
    3 KB (434 words) - 08:11, 13 September 2018
  • Lemasters 1998 Biochim Biophys Acta
    ...induced by t-butylhydroperoxide, onset of the mtPT is preceded by pyridine nucleotide oxidation, mitochondrial generation of reactive oxygen species, and an incr
    3 KB (471 words) - 18:46, 16 January 2021
  • Negmadjanov 2015 PLOS ONE
    ...tage-dependent anion channels (0.54 ± 0.05 vs. 0.23 ± 0.05 RU) and adenine nucleotide transporter (0.61 ± 0.11 vs. 0.22 ± 0.05 RU), as well as mitochondrial DN
    3 KB (422 words) - 00:09, 16 June 2021
  • Garcia-Rivas 2013 Abstract MiP2013
    ...proteins modulate the PTP, including the cyclophilin D (CyD), the adenine nucleotide translocator (ANT) and the SIRTUINS. In this regard, SIRT-3 has emerged rec
    3 KB (422 words) - 09:10, 18 July 2022
  • Wollenman 2017 PLOS ONE
    ...ics obtained with the substrate combinations, we conclude that the adenine nucleotide translocase, the dicarboxylate carrier, and the alpha-ketoglutarate exchang ::::* The most likely targets of chloride inhibition are the adenine nucleotide translocase and substrate transporters involved with succinate, glutamate,
    10 KB (1,407 words) - 19:20, 9 February 2022
  • Japiassu 2011 Crit Care Med
    ...(0.51 vs. 1.00 ng oligo/mL/10(6) cells, ''P'' = .02), but not the adenine nucleotide translocator, was significantly lower in patients with septic shock compare
    4 KB (485 words) - 10:27, 15 April 2020
  • Chicco 2018 J Biol Chem
    ...edox balance and help mitigate the effects of increased protein and purine nucleotide catabolism in hypoxia. Muscle accumulation of free amino acids favor these
    3 KB (455 words) - 12:50, 27 December 2021
  • Garlid KD 2012 Abstract Bioblast
    ...</sup> and H<sup>+</sup>. Also necessary for ATP synthesis are the adenine nucleotide translocase, which catalyzes electrophoretic ATP/ADP exchange, and the phos
    4 KB (506 words) - 16:24, 25 November 2015
  • Schoepf 2018 33rd Annual EAU Congress Copenhagen
    counterpart. In total, we detected 93 nucleotide variants in malignant samples, 26 (28%) thereof with heteroplasmy (HP) leve
    3 KB (467 words) - 13:00, 23 March 2018
  • Porter 2018 MiP2018a
    ...06±0.13 vs. 5.88±0.61 pmol/s/mg; P<0.001), a component of which was purine nucleotide (GDP) sensitive, indicating functional UCP1 (0.04±0.02 vs. 0.80±0.18 pmol
    3 KB (458 words) - 08:11, 13 September 2018
  • Kenny 2017 Diabetologia
    ...itrate synthase. This was accompanied by a significant decrease in adenine nucleotide translocase protein content.
    3 KB (472 words) - 10:31, 16 August 2018
  • Pereira 2015 Abstract MiPschool London 2015
    ...ries correlated to the formation of a complex between VDAC and the adenine nucleotide translocase: this affects Bax-dependent cytochrome c release. Biochim Bioph
    4 KB (479 words) - 12:09, 27 March 2018
  • Casanova 2014 Biochim Biophys Acta
    ..., ROX, Reactive oxygen species, Rhd123, Rhodamine 123, Ucp2, Ucp3, adenine nucleotide translocase 1, arbitrary fluorescence units, carbonyl cyanide 4-(trifluorom
    4 KB (470 words) - 17:12, 9 November 2017
  • Nedergaard 2017 MiP2017
    ...coupling of mitochondrial creatine kinase (sarcomeric isoform) and adenine nucleotide translocase and catalysed transfer of phosphoryl groups from ATP generated
    4 KB (531 words) - 17:56, 22 November 2017
  • Chicco 2018 MiP2018c
    ...edox balance and help mitigate the effects of increased protein and purine nucleotide catabolism. Muscle accumulation of free amino acids supports these adjustm
    4 KB (473 words) - 19:04, 10 January 2022
  • Galina 2013 Abstract MiP2013
    |enzymes=Adenine nucleotide translocase, Complex I, Complex II;succinate dehydrogenase, Marker enzyme,
    4 KB (493 words) - 14:15, 13 November 2017
  • Wojtczak 2012 Abstract Bioblast
    ...arboxyatractyloside, specific inhibitor of the mitochondrial [[ANT|adenine nucleotide transporter]]. Much lower effect of GDP or GTP on the release of ROS was ob
    4 KB (550 words) - 16:37, 7 November 2016
  • Melin 2022 JHEP Rep
    ...tion therapy, SASP, Senescence-associated secretory phenotype, SNP, Single nucleotide polymorphism, SOS, Sinusoidal obstruction syndrome, Fibrosis, Image guided
    4 KB (476 words) - 14:35, 28 November 2022
  • Shabalina 2017 MiP2017
    ...boxyatractyloside effects on brown-fat mitochondria imply that the adenine nucleotide translocator isoforms ANT1 and ANT2 may be responsible for basal and fatty-
    4 KB (522 words) - 13:45, 17 October 2017
  • Hoppel 2016a Abstract MitoFit Science Camp 2016
    ...oleoylcarnitine, as substrates and separately the activity of the adenine nucleotide translocase. We also directly measure Complex V (ATPase), and creatine kin
    4 KB (546 words) - 15:34, 20 October 2017
  • Chinopoulos 2012 Abstract Bioblast
    ...lavetz BI (2004) Expression of two succinyl-CoA synthetases with different nucleotide specificities in mammalian tissues. J Biol Chem 279: 36621-36624.
    4 KB (474 words) - 17:15, 3 February 2016

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