O2k-Publications: Topics
- Mitochondria and cell research
Mitochondrial physiology: MiP areas
- mt-Medicine (363 entries)
- Exercise physiology;nutrition;life style
- Comparative MiP;environmental MiP
- Pharmacology;toxicology
- mt-Biogenesis;mt-density
- Genetic knockout;overexpression
- Instruments;methods
Pathological states
- Alphabetical order
- Aging;senescence
- Alzheimer's
- Autism
- Cancer
- Cardiovascular
- COPD
- Diabetes
- Inherited
- Infectious
- Myopathy
- Neurodegenerative
- Obesity
- Parkinson's
- Sepsis
- Other
Stress conditions
- Alphabetical order
- Cell death
- Cryopreservation
- Hypoxia
- Ischemia-reperfusion injury and preservation
- Mitochondrial disease;degenerative disease and defect
- Oxidative stress;RONS
- Permeability transition
- Temperature: hypothermia; hyperthermia
Organisms
- Mammals
- Human
- Pig
- Horse
- Bovines
- Cat
- Dog
- Rabbit
- Mouse
- Rat
- Guinea pig
- Other mammals: including only mammals that are not listed as mammalian species above'.
- Model organisms
- Chicken (» Birds)
- Zebrafish (» Fishes)
- Drosophila (» Hexapods)
- Caenorhabditis elegans (» Nematodes)
- Artemia (» Crustaceans)
- Saccharomyces cerevisiae (» Fungi)
- Comparative MiP
- Non-mammals
- Birds (» Chicken)
- Reptiles - turtles, lizards, snakes, crocodiles, alligators
- Amphibians - frogs, toads, salamanders
- Fishes - bony fishes, carilaginous fishes (sharks, rays, skates) and jawless fishes (hagfish, lampreys); » Zebrafish
- Hexapods - insects, springtails; » Drosophila
- Crustaceans - crabs, shrimp, barnacles, etc.; » Artemia
- Annelids - polychaetes, e.g. lugworm Arenicola marina, oligochaetes, leeches
- Molluscs - gastropods, cephalopods, bivalves
- Nematodes » Caenorhabditis elegans
- Other invertebrates - urocordates (e.g. ascidians, sea squirts); cephalochordates (amphioxus, lancelets); echinoderms; chelicerates (e.g. spiders, scorpions, horseshoe crabs); myriapods (millipedes, centipedes); gastrotrichs; rotifers; ctenophores; nemerteans; tardigrades; platyhelminthes; cnidaria; porifera; ...
- Fungi - yeast, molds, mushrooms, etc.; » Saccharomyces cerevisiae
- Plants
- Protists - amoebas, ciliates, trypanosomes, dinoflagellates, diatoms, green algae, etc.
- Eubacteria - true bacteria, cyanobacteria, spirochetes
- Archaea - archaebacteria
Tissues and cells
- Tissues - alphabetical order
•• Fat •• Genital •• Heart •• Kidney •• Liver •• Lung;Gill •• Nervous system •• Skeletal muscle
- Cell types - alphabetical order
•• Blood cells •• Endothelial;epithelial;mesothelial cell •• Fibroblast •• Islet cell;pancreas;thymus •• Lymphocyte •• Platelet •• Stem cells
- Cell lines - alphabetical order
•• CHO •• HEK •• HeLa •• Neuroblastoma •• HUVEC •• Macrophage-derived cell lines
Preparations
- Intact organism •• Intact organ •• Intact cells •• Permeabilized cells •• Permeabilized tissue •• Homogenate •• Isolated mitochondria •• SMP •• Chloroplasts •• Enzyme •• Oxidase and biochemical oxidation
Enzymes
- Alphabetical order
•• Adenine nucleotide translocase •• Complex I •• Complex II;succinate dehydrogenase •• Complex III •• Complex IV;cytochrome c oxidase •• Complex V;ATP synthase •• Inner mt-membrane transporter •• Marker enzyme •• Supercomplex •• TCA cycle and matrix dehydrogenases •• Uncoupling protein
Regulation
- Alphabetical order
•• ADP •• ATP production •• Aerobic glycolysis •• Amino acid •• Calcium •• Coupling efficiency;uncoupling •• Cyt c •• Fatty acid •• Flux control •• Inhibitor •• Ion;substrate transport •• mt-Membrane potential •• Oxygen kinetics •• Q-junction effect •• Redox state •• Substrate •• Temperature •• Threshold;excess capacity •• Uncoupler
Coupling control states
# O2k-Publications MitoPedia: Pathway control states Comment O2k Total 1 P OXPHOS capacity Oxidative phosphorylation capacity, saturating [ADP] 2864 3093 2 R ROUTINE respiration Physiological state, intact cells 892 979 3 E Electron transfer system capacity Maximal noncoupled respiration 0 0 4 L LEAK respiration Resting state, non-phosphorylating respiration 2609 2768
Pathway control states
# O2k-Publications MitoPedia: Pathway control states Comment O2k Total 1 F F-pathway control state Fatty acid oxidation, level 5 608 752 2 N N-pathway control state NADH-linked, level 4 2473 2621 3 S S-pathway control state Succinate-linked, level 3 1684 1792 4 Gp Gp-pathway control state Glycerophosphate-linked, level 3 157 183 5 DQ Duorquinol-linked, level 2 26 31 6 CIV Complex IV single step Ascorbate & TMPD, level 1 702 730 7 NS NS-pathway control state Convergent CI- and CII-linked electron flow to the Q-junction 1579 1636 8 Other 132 148 9 ROX Residual oxygen consumption includes non-mitochondrial respiration 1519 1571
MiPMap combinations - examples
- Examples for specific combinations
- O2k-Publications: Human skeletal muscle •• O2k-Publications: Human heart •• O2k-Publications: Skeletal muscle - human vs mouse
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