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From Bioblast
Year | Reference | Coupling | Pathway | Preparation | Organism | Tissue;cell | |
---|---|---|---|---|---|---|---|
Thomas 2016 Neurodegeneration Therapeutics | 2016 | Thomas RR, Keeney PM, Berr SB, Khan SM, Portell FR, Shakenov MZ, Antkowiak PF, Kundu B, Tustison N, Brohawn DG, Bennett JP (2016) Recombinant human TFAM stimulates rat brain, rat cervical spinal cord and human neural stem cell mitochondrial bioenergetics. Neurodegeneration Therapeutics p41. | LEAK OXPHOS | N S CIV | Isolated mitochondria | Rat | Nervous system |
Gomez 2016 Thesis | 2016 | Gomez CR (2016) Mitochondrial responses to anoxia exposure in red eared sliders (Trachemys scripta). Master's Thesis p102. | LEAK OXPHOS ET | S | Permeabilized cells Isolated mitochondria | Reptiles | Heart Nervous system |
Lemieux 2016 Mitochondrion | 2016 | Lemieux H, Boemer F, van Galen G, Serteyn D, Amory H, Baise E, Cassart D, van Loon G, Marcillaud-Pitel C, Votion DM (2016) Mitochondrial function is altered in horse atypical myopathy. Mitochondrion 30:35-41. | OXPHOS ET | N S NS ROX | Permeabilized tissue | Horse | Skeletal muscle |
Richman 2016 Nat Commun | 2016 | Richman TR, Spåhr H, Ermer JA, Davies SM, Viola HM, Bates KA, Papadimitriou J, Hool LC, Rodger J, Larsson NG, Rackham O, Filipovska A (2016) Loss of the RNA-binding protein TACO1 causes late-onset mitochondrial dysfunction in mice. Nat Commun 7:11884. | LEAK OXPHOS | N S CIV | Isolated mitochondria | Mouse | Heart Liver |
Gariani 2016 Hepatology | 2016 | Gariani K, Menzies KJ, Ryu D, Wegner CJ, Wang X, Ropelle ER, Moullan N, Zhang H, Perino A, Lemos V, Kim B, Park YK, Piersigilli A, Pham TX, Yang Y, Ku SC, Koo SI, Fomitchova A, Cantó C, Schoonjans K, Sauve AA, Lee JY, Auwerx J (2016) Eliciting the mitochondrial unfolded protein response via NAD+ repletion reverses fatty liver disease. Hepatology 63:1190-204. | OXPHOS | N S | Permeabilized tissue | Mouse | Liver |
Gregg 2016 Diabetes | 2016 | Gregg T, Poudel C, Schmidt BA, Dhillon RS, Sdao SM, Truchan NA, Baar EL, Fernandez LA, Denu JM, Eliceiri KW, Rogers JD, Kimple ME, Lamming DW, Merrins MJ (2016) Pancreatic β cells from mice offset age-associated mitochondrial deficiency with reduced KATP channel activity. Diabetes 65:2700-10. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Human Mouse | Islet cell;pancreas;thymus Other cell lines |
Camacho-Pereira 2016 Cell Metab | 2016 | Camacho-Pereira J, Tarragó MG, Chini CC, Nin V, Escande C, Warner GM, Puranik AS, Schoon RA, Reid JM, Galina A, Chini EN (2016) CD38 dictates age-related NAD decline and mitochondrial dysfunction through an SIRT3-dependent mechanism. Cell Metab 23:1127-39. | LEAK ROUTINE OXPHOS ET | S ROX | Isolated mitochondria Intact cells | Human Mouse | Liver Lung;gill Other cell lines |
Ryan 2016 Diabetes | 2016 | Ryan TE, Schmidt CA, Green TD, Spangenburg EE, Neufer PD, McClung JM (2016) Targeted expression of catalase to mitochondria protects against ischemic myopathy in high fat fed mice. Diabetes 65:2553-68. | LEAK OXPHOS ET | N S CIV Other combinations ROX | Isolated mitochondria | Mouse | Skeletal muscle |
Tam 2016 Eur J Appl Physiol | 2016 | Tam E, Bruseghini P, Calabria E, Sacco LD, Doria C, Grassi B, Pietrangelo T, Pogliaghi S, Reggiani C, Salvadego D, Schena F, Toniolo L, Verratti V, Vernillo G, Capelli C (2016) Gokyo Khumbu/Ama Dablam Trek 2012: effects of physical training and high-altitude exposure on oxidative metabolism, muscle composition, and metabolic cost of walking in women. Eur J Appl Physiol 116:129-44. | LEAK OXPHOS | N S NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Lim 2016 FASEB J | 2016 | Lim SC, Hroudová J, Van Bergen NJ, Lopez Sanchez MI, Trounce IA, McKenzie M (2016) Loss of mitochondrial DNA-encoded protein ND1 results in disruption of complex I biogenesis during early stages of assembly. FASEB J 30:2236-48. | OXPHOS ET | N S NS ROX | Permeabilized cells | Human | Other cell lines |
Wang 2016 Toxicol Sci | 2016 | Wang L, Espinoza HM, MacDonald JW, Bammler TK, Williams CR, Yeh A, Louie KW, Marcinek DJ, Gallagher EP (2016) Olfactory Transcriptional Analysis of Salmon Exposed to Mixtures of Chlorpyrifos and Malathion Reveal Novel Molecular Pathways of Neurobehavioral Injury. Toxicol Sci 149:145-57. | LEAK OXPHOS ET | N S CIV NS ROX | Permeabilized tissue | Fishes | Endothelial;epithelial;mesothelial cell |
Farsijani 2016 J Clin Invest | 2016 | Farsijani NM, Liu Q, Kobayashi H, Davidoff O, Sha F, Fandrey J, Ikizler TA, O'Connor PM, Haase VH (2016) Renal epithelium regulates erythropoiesis via HIF-dependent suppression of erythropoietin. J Clin Invest 126:1425-37. | LEAK OXPHOS | N S CIV ROX | Permeabilized tissue | Mouse | Nervous system |
Cannon 2016 Lung | 2016 | Cannon DT, Liu J, Sakurai R, Rossiter HB, Rehan VK (2016) Impaired lung mitochondrial respiration following perinatal nicotine exposure in rats. Lung 194:325-8. | LEAK OXPHOS ET | N S CIV NS | Permeabilized tissue | Rat | Lung;gill |
Hamilton 2016 Am J Physiol Heart Circ Physiol | 2016 | Hamilton DJ, Zhang A, Li S, Cao TN, Smith JA, Vedula I, Cordero-Reyes AM, Youker KA, Torre-Amione G, Gupte AA (2016) Combination of angiotensin II and l-NG-nitroarginine methyl ester exacerbates mitochondrial dysfunction and oxidative stress to cause heart failure. Am J Physiol Heart Circ Physiol 310:H667-80. | LEAK OXPHOS | F N S NS Other combinations ROX | Permeabilized tissue Isolated mitochondria | Mouse | Heart |
Du 2016 J Exp Biol | 2016 | Du SN, Mahalingam S, Borowiec BG, Scott GR (2016) Mitochondrial physiology and reactive oxygen species production are altered by hypoxia acclimation in killifish (Fundulus heteroclitus). J Exp Biol 219:1130-8. | LEAK OXPHOS ET | N S CIV NS | Isolated mitochondria | Fishes | Liver |
Ehinger 2016 Mov Disord | 2016 | Ehinger JK, Morota S, Hansson MJ, Gesine P, Elmér E (2016) Mitochondrial respiratory function in peripheral blood cells from Huntington’s disease patients. Mov Disord doi:10.1002/mdc3.12308. | LEAK ROUTINE OXPHOS ET | N S CIV NS Other combinations ROX | Permeabilized cells Intact cells | Human | Blood cells Lymphocyte Platelet |
Lores-Arnaiz 2016 Neurochem Res | 2016 | Lores-Arnaiz S, Lombardi P, Karadayian AG, Orgambide F, Cicerchia D, Bustamante J (2016) Brain cortex mitochondrial bioenergetics in synaptosomes and non-synaptic mitochondria during aging. Neurochem Res 41:353-63. | LEAK ROUTINE OXPHOS ET | N S | Isolated mitochondria Intact cells | Mouse | Nervous system |
Amaral 2016 J Neurochem | 2016 | Amaral AU, Cecatto C, Castilho RF, Wajner M (2016) 2-methylcitric acid impairs glutamate metabolism and induces permeability transition in brain mitochondria. J Neurochem 137:62-75. | LEAK OXPHOS ET | N S NS | Isolated mitochondria | Rat | Nervous system |
Pamenter 2016 Biol Lett | 2016 | Pamenter ME, Gomez CR, Richards JG, Milsom WK (2016) Mitochondrial responses to prolonged anoxia in brain of red-eared slider turtles. Biol Lett 12. pii: 20150797. | LEAK OXPHOS ET | N S CIV ROX | Permeabilized tissue | Reptiles | Nervous system |
Schoepf 2016 FEBS J | 2016 | Schöpf B, Schäfer G, Weber A, Talasz H, Eder IE, Klocker H, Gnaiger E (2016) Oxidative phosphorylation and mitochondrial function differ between human prostate tissue and cultured cells. https://doi.org/10.1111/febs.13733 | LEAK OXPHOS ET | F N S NS Other combinations ROX | Permeabilized cells Permeabilized tissue | Human | Endothelial;epithelial;mesothelial cell Genital Other cell lines Fibroblast |
Strifler 2016 PLOS ONE | 2016 | Strifler G, Tuboly E, Szél E, Kaszonyi E, Cao C, Kaszaki J, Mészáros A, Boros M, Hartmann P (2016) Inhaled methane limits the mitochondrial electron transport chain dysfunction during experimental liver ischemia-reperfusion injury. PLOS ONE 11:e0146363. | LEAK OXPHOS | N S CIV NS ROX | Homogenate Isolated mitochondria | Rat | Liver |
Li 2016 Neurochem Int | 2016 | Li H, Liu Y, Lin LT, Wang XR, Du SQ, Yan CQ, He T, Yang JW, Liu CZ (2016) Acupuncture reversed hippocampal mitochondrial dysfunction in vascular dementia rats. Neurochem Int 92:35-42. | LEAK OXPHOS | S | Isolated mitochondria | Rat | Nervous system |
Krischek 2016 Mol Reprod Dev | 2016 | Krischek C, Janisch S, Naraballobh W, Brunner R, Wimmers K, Wicke M (2016) Altered incubation temperatures between embryonic Days 7 and 13 influence the weights and the mitochondrial respiratory and enzyme activities in breast and leg muscles of broiler embryos. Mol Reprod Dev 83:71-8. | LEAK OXPHOS | N S | Permeabilized tissue | Chicken | Skeletal muscle |
Johnson 2016 Diabetes | 2016 | Johnson ML, Distelmaier K, Lanza IR, Irving BA, Robinson MM, Konopka AR, Shulman GI, Nair KS (2016) Mechanism by which caloric restriction improves insulin sensitivity in sedentary obese adults. Diabetes 65:74-84. | LEAK OXPHOS ET | N S NS ROX | Isolated mitochondria | Human | Skeletal muscle |
Yamada 2016 J Physiol | 2016 | Yamada T, Takakura H, Jue T, Hashimoto T, Ishizawa R, Furuichi Y, Kato Y, Iwanaka N, Masuda K (2016) Myoglobin and the regulation of mitochondrial respiratory chain complex IV. J Physiol 594:483-95. | LEAK OXPHOS | N S CIV Other combinations ROX | Mouse | Skeletal muscle Other cell lines | |
Mills 2016 Cell Metab | 2016 | Mills KF, Yoshida S, Stein LR, Uchida K, Yoshino J, Imai SI (2016) Long-term administration of nicotinamide mononucleotide mitigates age-associated physiological decline in mice. Cell Metab 24:1–12. | OXPHOS LEAK ET | N S NS | Permeabilized tissue | Mouse | Skeletal muscle |
Doerrier 2016 Mitochondrion | 2016 | Doerrier C, García JA, Volt H, Díaz-Casado ME, Luna-Sánchez M, Fernández-Gil B, Escames G, López LC, Acuña-Castroviejo D (2016) Permeabilized myocardial fibers as model to detect mitochondrial dysfunction during sepsis and melatonin effects without disruption of mitochondrial network. Mitochondrion 27:56-63. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Mouse | Heart |
Berger 2016 Nat Commun | 2016 | Berger E, Rath E, Yuan D, Waldschmitt N, Khaloian S, Allgäuer M, Staszewski O, Lobner EM, Schöttl T, Giesbertz P, Coleman OI, Prinz M, Weber A, Gerhard M, Klingenspor M, Janssen KP, Heikenwalder M, Haller D (2016) Mitochondrial function controls intestinal epithelial stemness and proliferation. Nat Commun 7:13171. | LEAK OXPHOS | S ROX | Mouse | Endothelial;epithelial;mesothelial cell | |
Cacabelos 2016 Acta Neuropathol Commun | 2016 | Cacabelos D, Ramírez-Núñez O, Granado-Serrano AB, Torres P, Ayala V, Moiseeva V, Povedano M, Ferrer I, Pamplona R, Portero-Otin M, Boada J (2016) Early and gender-specific differences in spinal cord mitochondrial function and oxidative stress markers in a mouse model of ALS. Acta Neuropathol Commun 4:3. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized tissue Intact cells | Mouse | Nervous system Other cell lines |
Cagnone 2016 Sci Rep | 2016 | Cagnone GL, Tsai TS, Makanji Y, Matthews P, Gould J, Bonkowski MS, Elgass KD, Wong AS, Wu LE, McKenzie M, Sinclair DA, John JC (2016) Restoration of normal embryogenesis by mitochondrial supplementation in pig oocytes exhibiting mitochondrial DNA deficiency. Sci Rep 6:23229. | LEAK OXPHOS ET | S ROX | Isolated mitochondria | Pig | Genital |
Munro 2016 Free Radic Biol Med | 2016 | Munro D, Banh S, Sotiri E, Tamanna N, Treberg JR (2016) The thioredoxin and glutathione-dependent H2O2 consumption pathways in muscle mitochondria: Involvement in H2O2 metabolism and consequence to H2O2 efflux assays. Free Radic Biol Med 96:334-46. | LEAK OXPHOS | N S | Isolated mitochondria | Rat | Skeletal muscle |
Morad 2016 J Lipid Res | 2016 | Morad SA, Ryan TE, Neufer PD, Zeczycki TN, Davis TS, MacDougall MR, Fox TE, Tan SF, Feith DJ, Loughran TP Jr, Kester M, Claxton DF, Barth BM, Deering TG, Cabot MC (2016) Ceramide-tamoxifen regimen targets bioenergetic elements in acute myelogenous leukemia. J Lipid Res 57:1231-42. | LEAK OXPHOS | N S NS | Permeabilized cells | Human | Blood cells Other cell lines |
Distefano 2016 J Gerontol A Biol Sci Med Sci | 2016 | Distefano G, Standley RA, Dubé JJ, Carnero EA, Ritov VB, Stefanovic-Racic M, Toledo FG, Piva SR, Goodpaster BH, Coen PM (2016) Chronological age does not influence ex-vivo mitochondrial respiration and quality control in skeletal muscle. J Gerontol A Biol Sci Med Sci 72:535-42. | LEAK OXPHOS ET | N S NS | Permeabilized tissue | Human | Skeletal muscle |
Reynolds 2016 Am J Physiol Endocrinol Metab | 2016 | Reynolds MS, Hancock CR, Ray JD, Kener KB, Draney C, Garland K, Hardman J, Bikman BT, Tessem JS (2016) β-cell deletion of Nr4a1 and Nr4a3 nuclear receptors impedes mitochondrial respiration and insulin secretion. Am J Physiol Endocrinol Metab 311:E186-201. | LEAK ROUTINE OXPHOS ET | N S ROX | Permeabilized cells Intact cells | Rat | Islet cell;pancreas;thymus |
Kimball 2016 Thesis | 2016 | Kimball RL (2016) The role of hypoxia on pyruvate kinase M2, mammalian target of rapamycin, mitochondrial function, and cell invasion in the trophoblast. Master Thesis p55. | LEAK OXPHOS ET | N S NS ROX | Permeabilized cells | Human | Genital Other cell lines |
Viola 2016 J Physiol | 2016 | Viola H, Johnstone V, Szappanos HC, Richman T, Tsoutsman T, Filipovska A, Semsarian C, Hool L (2016) The L-type Ca2+ channel facilitates abnormal metabolic activity in the cTnI-G203S mouse model of hypertrophic cardiomyopathy. J Physiol 594:4051-70. | N S CIV | Isolated mitochondria | Mouse | Heart | |
Hagl 2016 Nutr Neurosci | 2016 | Hagl S, Berressem D, Grewal R, Grebenstein N, Frank J, Eckert GP (2016) Rice bran extract improves mitochondrial dysfunction in brains of aged NMRI mice. Nutr Neurosci 19:1-10. | LEAK OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Mouse | Nervous system |
Santos 2016 Insect Biochem Mol Biol | 2016 | Santos DE, Alberici LC, Hartfelder K (2016) Mitochondrial structure and dynamics as critical factors in honey bee (Apis mellifera L.) caste development. Insect Biochem Mol Biol 73:1-11. | LEAK OXPHOS ET | S | Permeabilized tissue | Hexapods | Fat |
Lund 2016 J Physiol | 2016 | Lund MT, Kristensen M, Hansen M, Tveskov L, Floyd AK, Støckel M, Vainer B, Poulsen SS, Helge JW, Prats C, Dela F (2016) Hepatic mitochondrial oxidative phosphorylation is normal in obese patients with and without type 2 diabetes. J Physiol 594:4351-8. | LEAK OXPHOS ET | F N S CIV NS ROX | Permeabilized tissue | Human | Liver |
Shrum 2016 J Kidney | 2016 | Shrum S, MacMillan-Crow LA, Parajuli N (2016) Cold storage exacerbates renal and mitochondrial dysfunction following transplantation. J Kidney 2 pii: 114. | OXPHOS | N S CIV | Permeabilized tissue | Rat | Kidney |
Bai 2016 PLOS ONE | 2016 | Bai F, Fink BD, Yu L, Sivitz WI (2016) Voltage-dependent regulation of Complex II energized mitochondrial oxygen flux. PLOS ONE 11:e0154982. | LEAK OXPHOS ET | N S CIV NS | Isolated mitochondria | Mouse | Heart Skeletal muscle Nervous system Liver |
Xiong 2016 Hypertension | 2016 | Xiong S, Wang P, Ma L, Gao P, Gong L, Li L, Li Q, Sun F, Zhou X, He H, Chen J, Yan Z, Liu D, Zhu Z (2016) Ameliorating endothelial mitochondrial dysfunction restores coronary function via transient receptor potential vanilloid 1-mediated protein kinase A/uncoupling protein 2 pathway. Hypertension 67:451-60. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Intact cells Permeabilized cells | Human | Endothelial;epithelial;mesothelial cell Other cell lines |
LaBarge 2016 FASEB J | 2016 | LaBarge SA, Migdal CW, Buckner EH, Okuno H, Gertsman I, Stocks B, Barshop BA, Nalbandian SR, Philp A, McCurdy CE, Schenk S (2016) p300 is not required for skeletal muscle metabolic adaptation to endurance exercise training. FASEB J 30:1623-33. | LEAK OXPHOS ET | F N NS ROX S Other combinations | Permeabilized tissue | Mouse | Skeletal muscle |
Zabielski 2016 Diabetes | 2016 | Zabielski P, Lanza IR, Gopala S, Holtz Heppelmann CJ, Bergen HR 3rd, Dasari S, Nair KS (2016) Altered skeletal muscle mitochondrial proteome as the basis of disruption of mitochondrial function in diabetic mice. Diabetes 65:561-73. | LEAK OXPHOS ET | F N S NS ROX | Permeabilized cells | Mouse | Skeletal muscle |
Nemeth 2016 FASEB J | 2016 | Németh B, Doczi J, Csete D, Kacso G, Ravasz D, Adams D, Kiss G, Nagy AM, Horvath G, Tretter L, Mócsai A, Csépányi-Kömi R, Iordanov I, Adam-Vizi V, Chinopoulos C (2016) Abolition of mitochondrial substrate-level phosphorylation by itaconic acid produced by LPS-induced Irg1 expression in cells of murine macrophage lineage. FASEB J 30:286-300. | LEAK OXPHOS | S | Isolated mitochondria | Mouse | Liver |
Salin 2016 J Exp Biol | 2016 | Salin K, Auer SK, Anderson GJ, Selman C, Metcalfe NB (2016) Inadequate food intake at high temperatures is related to depressed mitochondrial respiratory capacity. J Exp Biol 219:1356-62. | LEAK OXPHOS | N S CIV NS Other combinations ROX | Permeabilized tissue | Fishes | Skeletal muscle Liver |
Viola 2016 JACC: Basic to Translational Science | 2016 | Viola HM, Johnstone VPA, Szappanos HC, Richman TR, Tsoutsman T, Filipovska A, Semsarian C, Seidman JG, Seidman CE, Hool LC (2016) The role of the L-type Ca2+ channel in altered metabolic activity in a murine model of hypertrophic cardiomyopathy. JACC: Basic to Translational Science 1: 61–72. | OXPHOS | N S CIV | Isolated mitochondria | Mouse | Heart |
Liepinsh 2016 Biochem J | 2016 | Liepinsh E, Makrecka-Kuka M, Volska K, Kuka J, Makarova E, Antone U, Sevostjanovs E, Vilskersts R, Strods A, Tars K, Dambrova M (2016) Long-chain acylcarnitines determine ischaemia/reperfusion-induced damage in heart mitochondria. Biochem J 473:1191-202. | LEAK OXPHOS | S NS | Isolated mitochondria | Rat | Heart |
Jacobs 2016 J Physiol | 2016 | Jacobs RA, Lundby AM, Fenk S, Gehrig S, Siebenmann C, Flück D, Kirk N, Hilty MP, Lundby C (2016) Twenty-eight days of exposure to 3,454 m increases mitochondrial volume density in human skeletal muscle. J Physiol 594:1151-66. | LEAK OXPHOS ET | F N S CIV NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Chu 2016 World J Gastroenterol | 2016 | Chu MJ, Premkumar R, Hickey AJ, Jiang Y, Delahunt B, Phillips AR, Bartlett A (2016) Steatotic livers are susceptible to normothermic ischemia-reperfusion injury from mitochondrial Complex-I dysfunction. World J Gastroenterol 22:4673-84. | LEAK OXPHOS ET | N S NS ROX | Homogenate | Rat | Liver |
Fisar 2016b Folia Biol (Praha) | 2016 | Fisar Z, Hroudova J, Singh N, Koprivova A, Maceckova D (2016) Effect of simvastatin, coenzyme Q10, resveratrol, acetylcysteine and acetylcarnitine on mitochondrial respiration. Folia Biol (Praha) 62:53-66. | OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Pig | Nervous system |
Scott 2016 Thesis | 2016 | Scott KY (2016) Evaluation of cardiac mitochondrial function in the fructose-fed rat. Master's Thesis p98. | LEAK OXPHOS ET | F N S CIV ROX | Isolated mitochondria | Rat | Heart |
Queliconi 2016 PLOS ONE | 2016 | Queliconi BB, Kowaltowski AJ, Gottlieb RA (2016) Bicarbonate increases ischemia-reperfusion damage by inhibiting mitophagy. PLOS ONE 11:e0167678. | LEAK OXPHOS ET | S ROX | Isolated mitochondria | Rat | Heart |
Moll 2016 bioRxiv | 2016 | Moll CWI, Lindtner RA, Vogel GF, Brunner M, Gutleben K, Blauth M, Krumschnabel G, Ebner HL (2016) Bone marrow mesenchymal stem cells from osteoporotic patients do not show altered mitochondrial energetics or ultrastructure. bioRxiv doi.org/10.1101/046300. | LEAK ROUTINE OXPHOS ET | N S ROX | Intact cells Permeabilized cells | Human | Stem cells |
Baris 2016 Am J Physiol Regul Integr Comp Physiol | 2016 | Baris TZ, Blier PU, Pichaud N, Crawford DL, Oleksiak MF (2016) Gene by environmental interactions affecting oxidative phosphorylation and thermal sensitivity. Am J Physiol Regul Integr Comp Physiol 311:R157-65. | LEAK OXPHOS ET | CIV NS ROX S | Permeabilized tissue | Fishes | Heart |
Roy 2016 Free Radic Biol Med | 2016 | Roy J, Fauconnier J, Oger C, Farah C, Angebault-Prouteau C, Thireau J, Bideaux P, Scheuermann V, Bultel-Poncé V, Demion M, Galano JM, Durand T, Lee JC, Le Guennec JY (2016) Non-enzymatic oxidized metabolite of DHA, 4(RS)-4-F4t-neuroprostane protects the heart against reperfusion injury. Free Radic Biol Med 102:229-39. | OXPHOS ET | N S NS | Permeabilized cells | Rat | Heart |
Valek 2016 Redox Biol | 2016 | Valek L, Häussler A, Dröse S, Eaton P, Schröder K, Tegeder I (2016) Redox-guided axonal regrowth requires cyclic GMP dependent protein kinase 1: Implication for neuropathic pain. Redox Biol 11:176-91. | OXPHOS LEAK | N S CIV ROX | Homogenate | Mouse | Nervous system |
Casinelli 2016 Cell Death Discov | 2016 | Casinelli G, LaRosa J, Sharma M, Cherok E, Banerjee S, Branca M, Edmunds L, Wang Y, Sims-Lucas S, Churley L, Kelly S, Sun M, Stolz D, Graves JA (2016) N-Myc overexpression increases cisplatin resistance in neuroblastoma via deregulation of mitochondrial dynamics. Cell Death Discov 2:16082. | OXPHOS LEAK | N S | Permeabilized cells | Human | Nervous system Other cell lines |
Pambianco 2016 Cell Rep | 2016 | Pambianco S, Giovarelli M, Perrotta C, Zecchini S, Cervia D3, Di Renzo I, Moscheni C, Ripolone M, Violano R, Moggio M, Bassi MT, Puri PL, Latella L, Clementi E, De Palma C (2016) Reversal of defective mitochondrial biogenesis in limb-girdle muscular dystrophy 2D by independent modulation of histone and PGC-1α acetylation. Cell Rep 17:3010-23. | LEAK OXPHOS | F N S NS ROX | Permeabilized cells Isolated mitochondria Permeabilized tissue | Mouse | Skeletal muscle |
Fisar 2016a Folia Biol (Praha) | 2016 | Fisar Z, Hroudova J (2016) Pig brain mitochondria as a biological model for study of mitochondrial respiration. Folia Biol (Praha) 62:15-25. | LEAK OXPHOS ET | N S NS ROX | Isolated mitochondria | Pig | Nervous system |
Grundmanova 2016 Physiol Res | 2016 | Grundmanová M, Jarkovská D, Süß A, Tůma Z, Marková M, Grundman Z, El-Kadi A, Čedíková M, Štengl M, Kuncová J (2016) Propofol-induced mitochondrial and contractile dysfunction of the rat ventricular myocardium. Physiol Res 65:S601-9. | LEAK OXPHOS | N S CIV NS ROX | Permeabilized tissue | Rat | Heart |
Diana 2016 Surg Endosc | 2016 | Diana M, Noll E, Charles AL, Diemunsch P, Geny B, Liu YY, Marchegiani F, Schiraldi L, Agnus V, Lindner V, Swanström L, Dallemagne B, Marescaux J (2016) Precision real-time evaluation of bowel perfusion: accuracy of confocal endomicroscopy assessment of stoma in a controlled hemorrhagic shock model. Surg Endosc 31:680-91. | OXPHOS LEAK | S | Permeabilized tissue | Pig | Endothelial;epithelial;mesothelial cell |
Timpani 2016 Neurotherapeutics | 2016 | Timpani CA, Trewin AJ, Stojanovska V, Robinson A, Goodman CA, Nurgali K, Betik AC, Stepto N, Hayes A, McConell GK, Rybalka E (2016) Attempting to compensate for reduced neuronal nitric oxide synthase protein with nitrate supplementation cannot overcome metabolic dysfunction but rather has detrimental effects in Dystrophin-deficient mdx muscle. Neurotherapeutics 14:429-46. | LEAK OXPHOS ET | N CIV NS Other combinations ROX S | Permeabilized tissue | Mouse | Skeletal muscle |
Briston 2016 Sci Rep | 2016 | Briston T, Lewis S, Koglin M, Mistry K, Shen Y, Hartopp N, Katsumata R, Fukumoto H, Duchen MR, Szabadkai G, Staddon JM, Roberts M, Powney B (2016) Identification of ER-000444793, a Cyclophilin D-independent inhibitor of mitochondrial permeability transition, using a high-throughput screen in cryopreserved mitochondria. Sci Rep 6:37798. | LEAK OXPHOS ET | N S ROX | Isolated mitochondria | Rat | Liver |
Strifler 2016b PLOS ONE | 2016 | Strifler G, Tuboly E, Görbe A, Boros M, Pécz D, Hartmann P (2016) Targeting mitochondrial dysfunction with L-alpha glycerylphosphorylcholine. PLOS ONE 11:e0166682. | LEAK OXPHOS ET | N S NS Other combinations ROX | Homogenate | Rat | Liver |
Torres 2016 Redox Biol | 2016 | Torres S, Matías N, Baulies A, Nuñez S, Alarcon-Vila C, Martinez L, Nuño N, Fernandez A, Caballeria J, Levade T, Gonzalez-Franquesa A, Garcia-Rovés P, Balboa E, Zanlungo S, Fabrías G, Casas J, Enrich C, Garcia-Ruiz C, Fernández-Checa JC (2016) Mitochondrial GSH replenishment as a potential therapeutic approach for Niemann Pick type C disease. Redox Biol 11:60-72. | LEAK ROUTINE OXPHOS ET | N S ROX | Homogenate Intact cells | Human Mouse | Nervous system Liver Endothelial;epithelial;mesothelial cell Fibroblast |
Frey 2016 Biochim Biophys Acta | 2016 | Frey S, Geffroy G, Desquiret-Dumas V, Gueguen N, Bris C, Belal S, Amati-Bonneau P, Chevrollier A, Barth M, Henrion D, Lenaers G, Bonneau D, Reynier P, Procaccio V (2016) The addition of ketone bodies alleviates mitochondrial dysfunction by restoring complex I assembly in a MELAS cellular model. Biochim Biophys Acta 1863:284-91. | ROUTINE LEAK ET | N S NS | Permeabilized cells Intact cells | Human | Nervous system |
Mezera 2016 Oxid Med Cell Longev | 2016 | Mezera V, Endlicher R, Kucera O, Sobotka O, Drahota Z, Cervinkova Z (2016) Effects of epigallocatechin gallate on tert-butyl hydroperoxide-induced mitochondrial dysfunction in rat liver mitochondria and hepatocytes. Oxid Med Cell Longev 7573131:8pp. | LEAK OXPHOS | N S | Permeabilized cells Isolated mitochondria | Rat | Liver |
Strifler 2016 Magyar Sebeszet | 2016 | Strifler G, Meszaros A, Pecz D, Ficzere A, Barath B, Mihaly B, Hartmann P (2016) A májfunkció vizsgálata respirometriával - Examination of liver mitochondria with respirometry. Magyar Sebészet 69:194–8. | OXPHOS LEAK | N S CIV NS ROX Other combinations | Homogenate | Rat | Liver |
Ferguson 2016 J Bioenerg Biomembr | 2016 | Ferguson MA, Sutton RM, Karlsson M, Sjövall F, Becker LB, Berg RA, Margulies SS, Kilbaugh TJ (2016) Increased platelet mitochondrial respiration after cardiac arrest and resuscitation as a potential peripheral biosignature of cerebral bioenergetic dysfunction. J Bioenerg Biomembr 48:269-79. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Homogenate Intact cells | Pig | Nervous system Platelet |
Bonifacio 2016 Arch Toxicol | 2016 | Bonifacio A, Mullen PJ, Mityko IS, Navegantes LC, Bouitbir J, Krähenbühl S (2016) Simvastatin induces mitochondrial dysfunction and increased atrogin-1 expression in H9c2 cardiomyocytes and mice in vivo. Arch Toxicol 90:203-15. doi: 10.1007/s00204-014-1378-4 | LEAK OXPHOS ET | N S DQ CIV NS | Permeabilized cells Permeabilized tissue Intact cells | Rat | Heart |
Hancock 2016 Amino Acids | 2016 | Hancock CN, Liu W, Alvord WG, Phang JM (2016) Co-regulation of mitochondrial respiration by proline dehydrogenase/oxidase and succinate. Amino Acids 48:859-72. | LEAK ROUTINE ET | S Other combinations ROX | Isolated mitochondria Oxidase;biochemical oxidation Intact cells | Mouse | Liver |
Singh 2016 Mol Neurobiol | 2016 | Singh N, Hroudová J, Fišar Z (2016) In vitro effects of cognitives and nootropics on mitochondrial respiration and monoamine oxidase activity. Mol Neurobiol 54:5894-904. | LEAK | N S ROX | Isolated mitochondria | Pig | Nervous system |
Chowdhury 2015 Biosci Rep | 2016 | Chowdhury SK, Djordjevic J, Albensi B, Fernyhough P (2015) Simultaneous evaluation of substrate-dependent oxygen consumption rates and mitochondrial membrane potential by TMRM and safranin in cortical mitochondria. Biosci Rep 36:e00286. | LEAK OXPHOS ET | N S NS ROX | Homogenate Isolated mitochondria | Mouse | Nervous system |
Jardim-Messeder 2016 Anticancer Res | 2016 | Jardim-Messeder D, Moreira-Pacheco F (2016) 3-Bromopyruvic acid inhibits tricarboxylic acid cycle and glutaminolysis in HepG2 cells. Anticancer Res 36:2233-41. | OXPHOS | CIV N S | Isolated mitochondria | Mouse | Liver Kidney |
Koncsos 2016 Am J Physiol Heart Circ Physiol | 2016 | Koncsos G, Varga ZV, Baranyai T, Boengler K, Rohrbach S, Li L, Schlüter KD, Schreckenberg R, Radovits T, Oláh A, Mátyás C, Lux Á, Al-Khrasani M, Komlódi T, Bukosza N, Máthé D, Deres L, Barteková M, Rajtík T, Adameová A, Szigeti K, Hamar P, Helyes Z, Tretter L, Pacher P, Merkely B, Giricz Z, Schulz R, Ferdinandy P (2016) Diastolic dysfunction in prediabetic male rats: role of mitochondrial oxidative stress. Am J Physiol Heart Circ Physiol 311:H927-43. | OXPHOS | N S NS | Isolated mitochondria | Rat | Heart |
Mills 2016 Cell | 2016 | Mills EL, Kelly B, Logan A, Costa ASH, Varma M, Bryant CE, Tourlomousis P, Däbritz JHM, Gottlieb E, Latorre I, Corr SC, McManus G, Ryan D, Jacobs HT, Szibor M, Xavier RJ, Braun T, Frezza C, Murphy MP, O’Neill LA (2016) Succinate dehydrogen2016ase supports metabolic repurposing of mitochondria to drive inflammatory macrophages. Cell 167:457-70.e13. https://doi.org/10.1016/j.cell.2016.08.064. | S | Macrophage-derived | |||
Raesaenen 2016 Proc Natl Acad Sci U S A | 2016 | Räsänen M, Degerman J, Nissinen TA, Miinalainen I, Kerkelä R, Siltanen A, Backman JT, Mervaala E, Hulmi JJ, Kivelä R, Alitalo K (2016) VEGF-B gene therapy inhibits doxorubicin-induced cardiotoxicity by endothelial protection. Proc Natl Acad Sci U S A 113:13144-49. | LEAK OXPHOS ET | N S NS | Homogenate | Mouse | Heart |
Alvarez-Mora 2016 Mol Neurobiol | 2016 | Alvarez-Mora MI, Rodriguez-Revenga L, Madrigal I, Guitart-Mampel M, Garrabou G, Milà M (2016) Impaired mitochondrial function and dynamics in the pathogenesis of FXTAS. Mol Neurobiol 54:6896-902. | ROUTINE | N S NS | Intact cells | Human | Fibroblast |
Witt 2016 Metab Brain Dis | 2016 | Witt AM, Larsen FS, Bjerring PN (2016) Accumulation of lactate in the rat brain during hyperammonaemia is not associated with impaired mitochondrial respiratory capacity. Metab Brain Dis 32:461-70. | LEAK OXPHOS ET | N S NS ROX | Homogenate | Rat | Nervous system |
Chakraborty 2016 Pancreatology | 2016 | Chakraborty M, Hickey AJ, Petrov MS, Macdonald JR, Thompson N, Newby L, Sim D, Windsor JA, Phillips AR (2016) Mitochondrial dysfunction in peripheral blood mononuclear cells in early experimental and clinical acute pancreatitis. Pancreatology 16:739-47. | LEAK OXPHOS ROUTINE ET | N Gp CIV NS ROX S | Permeabilized cells | Human Rat | Blood cells |
Maarman 2016 J Appl Physiol (1985) | 2016 | Maarman GJ, Andrew BM, Blackhurst DM, Ojuka EO (2016) Melatonin protects against uric acid-induced mitochondrial dysfunction, oxidative stress, and triglyceride accumulation in C2C12 myotubes. J Appl Physiol (1985) 122:1003-10. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Intact cells | Mouse | Skeletal muscle |
Hartmannova 2016 Hum Mol Genet | 2016 | Hartmannová H, Piherová L, Tauchmannová K, Kidd K, Acott PD, Crocker JF, Oussedik Y, Mallet M, Hodaňová K, Stránecký V, Přistoupilová A, Barešová V, Jedličková I, Živná M, Sovová J, Hůlková H, Robins V, Vrbacký M, Pecina P, Kaplanová V, Houštěk J, Mráček T, Thibeault Y, Bleyer AJ, Kmoch S (2016) Acadian variant of Fanconi syndrome is caused by mitochondrial respiratory chain complex I deficiency due to a non-coding mutation in complex I assembly factor NDUFAF6. Hum Mol Genet 25:4062-79. | LEAK OXPHOS ET | N S Gp CIV NS ROX | Permeabilized cells | Human | Fibroblast |
Shirey 2016 Biochemistry | 2016 | Shirey K, Stover KR, Cleary J, Hoang N, Hosler J (2016) Membrane-anchored cyclic peptides as effectors of mitochondrial oxidative phosphorylation. Biochemistry 55:2100-11. | LEAK OXPHOS ET | CIV NS N S | Isolated mitochondria SMP | Rat | Heart Liver |
Dechandt 2016 Anal Biochem | 2016 | Dechandt CRP, Couto-Lima CA, Alberici LC (2016) Triglyceride depletion of brown adipose tissue enables analysis of mitochondrial respiratory function in permeabilized biopsies. Anal Biochem 515:55-60. | LEAK OXPHOS ET | N S ROX | Permeabilized tissue | Rat | Fat |
Reich 2016 Thesis | 2016 | Reich V (2016) Pathophysiologie und Verfahrensentwicklung: Mechanismen der Metabolisierung von Schwefelwasserstoff im mitochondrialen Atmungskreislauf von Lungenalveolarmakrophagen. Dissertation p91. | LEAK OXPHOS ET | N S CIV NS ROX | Intact cells Permeabilized cells | Mouse | Macrophage-derived |
Berressem 2016 PLOS ONE | 2016 | Berressem D, Koch K, Franke N, Klein J, Eckert GP (2016) Intravenous treatment with a long-chain omega-3 lipid emulsion provides neuroprotection in a murine model of ischemic stroke - a pilot study. PLOS ONE 11:e0167329. | LEAK OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Mouse | Nervous system |
Gorbacheva 2016 International Symposium Mitochondrial Motility | 2016 | Gorbacheva OS, Strutynskyi RB, Khmil NV, Belosludtseva NV, Murzaeva SV, Korobeynikova MO, Alilova GA, Lezhnev EI, Mironova GD (2016) Study of the influence of flocalin on the energy and ion exchanges in rat liver mitochondria. International Symposium Mitochondrial Motility 73-7. | LEAK | F N S | Rat | Liver | |
Stier 2016 Methods Ecol Evol | 2016 | Stier A, Romestaing C, Schull Q, Lefol E, Robin JP, Roussel D, Bize P (2016) How to measure mitochondrial function in birds using red blood cells: a case study in the king penguin and perspectives in ecology and evolution. Methods Ecol Evol doi:10.1111/2041-210X.12724. | LEAK ROUTINE OXPHOS ET | N S ROX | Permeabilized tissue Intact cells | Birds | Skeletal muscle Blood cells |
Pohland 2016 Neurochem Res | 2016 | Pohland M, Hagl S, Pellowska M, Wurglics M, Schubert-Zsilavecz M, Eckert GP (2016) MH84: a novel γ-secretase modulator/PPARγ agonist-improves mitochondrial dysfunction in a cellular model of Alzheimer's disease. Neurochem Res 41:231-42. | LEAK OXPHOS ET | N S CIV NS ROX | Permeabilized cells | Human | Kidney HEK |
Asseburg 2016 Neuromolecular Med | 2016 | Asseburg H, Schäfer C, Müller M, Hagl S, Pohland M, Berressem D, Borchiellini M, Plank C, Eckert GP (2016) Effects of grape skin extract on age-related mitochondrial dysfunction, memory and life span in C57BL/6J mice. Neuromolecular Med 18:378-95. | LEAK OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Mouse | Nervous system |
Nissinen 2016 Sci Rep | 2016 | Nissinen TA, Degerman J, Räsänen M, Poikonen AR, Koskinen S, Mervaala E, Pasternack A, Ritvos O, Kivelä R, Hulmi JJ (2016) Systemic blockade of ACVR2B ligands prevents chemotherapy-induced muscle wasting by restoring muscle protein synthesis without affecting oxidative capacity or atrogenes. Sci Rep 6:32695. | LEAK OXPHOS ET | N S CIV NS ROX | Homogenate | Mouse | Skeletal muscle |
Gariani 2016 J Hepatol | 2016 | Gariani K, Ryu D, Menzies KJ, Yi HS, Stein S, Zhang H, Perino A, Lemos V, Katsyuba E, Jha P, Vijgen S, Rubbia-Brandt L, Kim YK, Kim JT, Kim KS, Shong M, Schoonjans K, Auwerx J (2016) Inhibiting poly ADP-ribosylation increases fatty acid oxidation and protects against fatty liver disease. J Hepatol 66:132-41. | OXPHOS | N S NS | Permeabilized tissue | Mouse | Liver |
Du 2016 Thesis | 2016 | Du X (2016) Anthropogenic pollution effects on mitochondrial energy metabolism, gene expression, and genotypes of natural Fundulus heteroclitus populations. Dissertation p175. | LEAK OXPHOS ET | S CIV ROX N NS | Permeabilized cells | Fishes | Liver |
Fisar 2016 Curr Alzheimer Res | 2016 | Fišar Z, Hroudová J, Hansíková H, Spáčilová J, Lelková P, Wenchich L, Jirák R, Zvěřová M, Zeman J, Martásek P, Raboch J (2016) Mitochondrial respiration in the platelets of patients with Alzheimer's disease. Curr Alzheimer Res 13:930-41. | LEAK OXPHOS ET | N S NS ROX | Intact cells Permeabilized cells | Human | Blood cells Platelet |
Fink 2016 Am J Physiol Regul Integr Comp Physiol | 2016 | Fink BD, Bai F, Yu L, Sivitz WI (2016) Impaired utilization of membrane potential by complex II-energized mitochondria of obese, diabetic mice assessed using ADP recycling methodology. Am J Physiol Regul Integr Comp Physiol 311:756-63. | OXPHOS LEAK | S | Isolated mitochondria | Mouse | Skeletal muscle |
Amigo 2016 Aging Cell | 2016 | Amigo I, Menezes-Filho SL, Luévano-Martínez LA, Chausse B, Kowaltowski AJ (2016) Caloric restriction increases brain mitochondrial calcium retention capacity and protects against excitotoxicity. Aging Cell 16:73-81. | LEAK OXPHOS ET | N S | Isolated mitochondria | Mouse | Nervous system |
Wolter 2016 J Thromb Haemost | 2016 | Wolter J, Schild L, Bock F, Hellwig A, Gadi I, Al-Dabet MM, Ranjan S, Rönicke R, Nawroth PP, Petersen KU, Mawrin C, Shahzad K, Isermann B (2016) Thrombomodulin-dependent protein C activation is required for mitochondrial function and myelination in the central nervous system. J Thromb Haemost 14:2212-26. | OXPHOS | N S | Isolated mitochondria | Mouse | Nervous system |
Villani 2016 Mol Metab | 2016 | Villani LA, Smith BK, Marcinko K, Ford RJ, Broadfield LA, Green AE, Houde VP, Muti P, Tsakiridis T, Steinberg GR (2016) The diabetes medication Canagliflozin reduces cancer cell proliferation by inhibiting mitochondrial complex-I supported respiration. Mol Metab 5:1048-56. | OXPHOS | N S ROX | Permeabilized cells | Human | Genital |
Galli 2016 Am J Physiol Regul Integr Comp Physiol | 2016 | Galli GL, Crossley J, Elsey RM, Dzialowski EM, Shiels HA, Crossley DA 2nd (2016) Developmental plasticity of mitochondrial function in American alligators, Alligator mississippiensis. Am J Physiol Regul Integr Comp Physiol 311:R1164-72. | LEAK OXPHOS ET | N S CIV Other combinations ROX | Isolated mitochondria | Reptiles | Heart |
King 2016 Redox Biol | 2016 | King AL, Mantena SK, Andringa KK, Millender-Swain T, Dunham-Snary KJ, Oliva CR, Griguer CE, Bailey SM (2016) The methyl donor S-adenosylmethionine prevents liver hypoxia and dysregulation of mitochondrial bioenergetic function in a rat model of alcohol-induced fatty liver disease. Redox Biol 9:188-97. | OXPHOS | S | Isolated mitochondria | Rat | Liver |
Granata 2016 FASEB J | 2016 | Granata C, Oliveira RS, Little JP, Renner K, Bishop DJ (2016) Mitochondrial adaptations to high-volume exercise training are rapidly reversed after a reduction in training volume in human skeletal muscle. FASEB J 30:3413-23. https://doi.org/10.1096/fj.201500100R | LEAK OXPHOS ET | N S CIV NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Rackham 2016 Cell Rep | 2016 | Rackham O, Busch JD, Matic S, Siira SJ, Kuznetsova I, Atanassov I, Ermer JA, Shearwood AM, Richman TR, Stewart JB, Mourier A, Milenkovic D, Larsson NG, Filipovska A (2016) Hierarchical RNA processing is required for mitochondrial ribosome assembly. Cell Rep 16:1874-90. | LEAK OXPHOS ET | N S CIV NS Other combinations | Isolated mitochondria | Mouse | Heart |
Kilbaugh 2016 Mitochondrion | 2016 | Kilbaugh TJ, Karlsson M, Duhaime AC, Hansson MJ, Elmer E, Margulies SS (2016) Mitochondrial response in a toddler-aged swine model following diffuse non-impact traumatic brain injury. Mitochondrion 26:19-25. | LEAK OXPHOS ET | N S CIV NS ROX | Homogenate | Pig | Nervous system |
Tsai 2016 Sci Rep | 2016 | Tsai HH, Chang SC, Chou CH, Weng TP, Hsu CC, Wang JS (2016) Exercise training alleviates hypoxia-induced mitochondrial dysfunction in the lymphocytes of sedentary males. Sci Rep 6:35170. | LEAK ROUTINE OXPHOS ET | F N S NS Other combinations ROX | Permeabilized cells Intact cells | Human | Lymphocyte Blood cells |
De Carvalho 2016 J Cell Biochem | 2016 | de Carvalho AK, da Silva S, Serafini E, de Souza DR, Farias HR, de Bem Silveira G, Silveira PC, de Souza CT, Portela LV, Muller AP (2016) Prior exercise training prevent hyperglycemia in STZ mice by increasing hepatic glycogen and mitochondrial function on skeletal muscle. J Cell Biochem 118:678-85. | LEAK OXPHOS | S | Homogenate | Mouse | Skeletal muscle Liver |
Karlsson 2016 Shock | 2016 | Karlsson M, Hara N, Morata S, Sjövall F, Kilbaugh T, Hansson MJ, Uchino H, Elmér E (2016) Diverse and tissue-specific mitochondrial respiratory response in a mouse model of sepsis-induced multiple organ failure. Shock 45:404-10. | LEAK OXPHOS ET | N S CIV NS | Homogenate | Mouse | Nervous system Liver |
Brecht 2016 Toxicol In Vitro | 2016 | Brecht K, Riebel V, Couttet P, Paech F, Wolf A, Chibout SD, Pognan F, Krähenbühl S, Uteng M (2016) Mechanistic insights into selective killing of OXPHOS-dependent cancer cells by arctigenin. Toxicol In Vitro 40:55-65. | LEAK OXPHOS ET | N S CIV Other combinations ROX DQ | Permeabilized cells | Human | Islet cell;pancreas;thymus |
Silva Ramos 2016 Biochim Biophys Acta | 2016 | Silva Ramos E, Larsson NG, Mourier A (2016) Bioenergetic roles of mitochondrial fusion. Biochim Biophys Acta 1857:1277-83. | LEAK OXPHOS ET | S Gp | Permeabilized cells | Mouse | Fibroblast |
Duteil 2016 Cell Rep | 2016 | Duteil D, Tosic M, Lausecker F, Nenseth HZ, Müller JM, Urban S, Willmann D, Petroll K, Messaddeq N, Arrigoni L, Manke T, Kornfeld JW, Brüning JC, Zagoriy V, Meret M, Dengjel J, Kanouni T, Schüle R (2016) Lsd1 ablation triggers metabolic reprogramming of brown adipose tissue. Cell Rep 17:1008-21. | ET | F N S NS | Permeabilized tissue | Mouse | Fat |
Van Schaardenburgh 2016 PLOS ONE | 2016 | van Schaardenburgh M, Wohlwend M, Rognmo Ø, Mattsson EJ (2016) Mitochondrial respiration after one session of calf raise exercise in patients with peripheral vascular disease and healthy older adults. PLOS ONE 11:e0165038. | LEAK OXPHOS ET | F N S NS | Permeabilized tissue | Human | Skeletal muscle |
McCurdy 2016 JCI Insight | 2016 | McCurdy CE, Schenk S, Hetrick B, Houck J, Drew BG, Kaye S, Lashbrook M, Bergman BC, Takahashi DL, Dean TA, Nemkov T, Gertsman I, Hansen KC, Philp A, Hevener AL, Chicco AJ, Aagaard KM, Grove KL, Friedman JE (2016) Maternal obesity reduces oxidative capacity in fetal skeletal muscle of Japanese macaques. JCI Insight 1:e86612. | LEAK OXPHOS ET | F N S NS | Permeabilized tissue | Other mammals | Skeletal muscle |
Wang 2016 J Biol Chem | 2016 | Wang H, Lu J, Edmunds LR, Kulkarni S, Dolezal J, Tao J, Ranganathan S, Jackson L, Fromherz M, Stolz DB, Uppala R, Bharathi S, Monga SP, Goetzman ES, Prochownik EV (2016) Coordinated activities of multiple Myc-dependent and Myc-independent biosynthetic pathways in Hepatoblastoma. J Biol Chem 291:26241-51. | OXPHOS LEAK | N S NS | Homogenate | Mouse | Liver |
Tretter 2016 Biochim Biophys Acta | 2016 | Tretter L, Patocs A, Chinopoulos C (2016) Succinate, an intermediate in metabolism, signal transduction, ROS, hypoxia, and tumorigenesis. https://doi.org/10.1016/j.bbabio.2016.03.012 | LEAK OXPHOS | N S NS | |||
Melenovsky 2016 Eur J Heart Fail | 2016 | Melenovsky V, Petrak J, Mracek T, Benes J, Borlaug BA, Nuskova H, Pluhacek T, Spatenka J, Kovalcikova J, Drahota Z, Kautzner J, Pirk J, Houstek J (2016) Myocardial iron content and mitochondrial function in human heart failure: a direct tissue analysis. Eur J Heart Fail 19:522-30. | N S | Homogenate | Human | Heart | |
Bagur 2016 Biochim Biophys Acta | 2016 | Bagur R, Tanguy S, Foriel S, Grichine A, Sanchez C, Pernet-Gallay K, Kaambre T, Kuznetsov AV, Usson Y, Boucher F, Guzun R (2016) The impact of cardiac ischemia/reperfusion on the mitochondria-cytoskeleton interactions. Biochim Biophys Acta 1862:1159-71. | OXPHOS LEAK | N S | Permeabilized tissue | Rat | Heart |
MiPNet17.03 Shredder vs Fibers | 2015-06-18 | Mitochondrial respiration in permeabilized fibers versus homogenate from fish liver and heart. An application study with the PBI-Shredder. | LEAK OXPHOS ET | N S NS | Homogenate | Fishes | Heart Liver |
Johnson 2015 Aging Cell | 2015 | Johnson ML, Lalia AZ, Dasari S, Pallauf M, Fitch M, Hellerstein MK, Lanza IR (2015) Eicosapentaenoic acid but not docosahexaenoic acid restores skeletal muscle mitochondrial oxidative capacity in old mice. Aging Cell 14:734-43. | LEAK OXPHOS | F N S NS ROX | Isolated mitochondria | Mouse | Skeletal muscle |
Agil 2015 J Pineal Res | 2015 | Agil A, El-Hammadi M, Jiménez-Aranda A, Tassi M, Abdo W, Fernández-Vázquez G, Reiter RJ (2015) Melatonin reduces hepatic mitochondrial dysfunction in diabetic obese rats. J Pineal Res 59:70-9. | LEAK OXPHOS | S | Isolated mitochondria | Rat | Liver |
Li 2015 Sci Rep | 2015 | Li P, Wang B, Sun F, Li Y, Li Q, Lang H, Zhao Z, Gao P, Zhao Y, Shang Q, Liu D, Zhu Z (2015) Mitochondrial respiratory dysfunctions of blood mononuclear cells link with cardiac disturbance in patients with early-stage heart failure. Sci Rep 5:10229. | LEAK ROUTINE OXPHOS ET | N S NS | Intact cells | Human | Blood cells Lymphocyte |
Youcef 2015 Biochem Pharmacol | 2015 | Youcef G, Belaidi E, Waeckel L, Fazal L, Clemessy M, Vincent MP, Zadigue G, Richer C, Alhenc-Gelas F, Ovize M, Pizard A (2015) Tissue kallikrein is required for the cardioprotective effect of cyclosporin A in myocardial ischemia in the mouse. Biochem Pharmacol 94:22-9. | LEAK OXPHOS | N S CIV | Isolated mitochondria | Mouse | Heart |
Acosta 2015 Obesity (Silver Spring) | 2015 | Acosta A, Camilleri M, Shin A, Vazquez-Roque MI, Iturrino J, Lanza IR, Nair KS, Burton D, O'Neill J, Eckert D, Carlson P, Vella A, Zinsmeister AR (2015) Association of UCP-3 rs1626521 with obesity and stomach functions in humans. Obesity (Silver Spring) 23:898-906. | LEAK OXPHOS | N S NS | Isolated mitochondria | Human | Skeletal muscle |
Boerma 2015 Radiat Res | 2015 | Boerma M, Singh P, Sridharan V, Tripathi P, Sharma S, Singh SP (2015) Effects of local heart irradiation in a glutathione S-transferase alpha 4-null mouse model. Radiat Res 183:610-9. | OXPHOS | N S CIV ROX | Permeabilized tissue | Mouse | Heart |
Schwarzkopf 2015 Neuroscience | 2015 | Schwarzkopf TM, Koch K, Klein J (2015) Reduced severity of ischemic stroke and improvement of mitochondrial function after dietary treatment with the anaplerotic substance triheptanoin. Neuroscience 300:201-9. | LEAK OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Mouse | Nervous system |
Labieniec-Watala 2015 Int J Pharm Sci Res | 2015 | Labieniec-Watala M, Przygodzki T, Siewiera K, Podsedek A, Watala C (2015) Facts and artifacts in the evaluation of the anti-diabetic activity of spent hop extract in rat hearts in the “experimental model of diabetes. Int J Pharm Sci Res 1:106. | LEAK OXPHOS ET | S ROX | Isolated mitochondria | Rat | Heart |
Yan 2015 BMC Cancer | 2015 | Yan B, Stantic M, Zobalova R, Bezawork-Geleta A, Stapelberg M, Stursa J, Prokopova K, Dong L, Neuzil J (2015) Mitochondrially targeted vitamin E succinate efficiently kills breast tumour-initiating cells in a complex II-dependent manner. BMC Cancer 15:401. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human Mouse | Genital Other cell lines |
Kluckova 2015 Cell Death Dis | 2015 | Kluckova K, Sticha M, Cerny J, Mracek T, Dong L, Drahota Z, Gottlieb E, Neuzil J, Rohlena J (2015) Ubiquinone-binding site mutagenesis reveals the role of mitochondrial complex II in cell death initiation. Cell Death Dis 6:e1749. | OXPHOS ET | S ROX | Permeabilized cells Isolated mitochondria | Other mammals | Lung;gill Other cell lines Fibroblast |
Pasdar 2015 PLoS One | 2015 | Pasdar EA, Smits M, Stapelberg M, Bajzikova M, Stantic M, Goodwin J, Yan B, Stursa J, Kovarova J, Sachaphibulkij K, Bezawork-Geleta A, Sobol M, Filimonenko A, Tomasetti M, Zobalova R, Hozak P, Dong LF, Neuzil J (2015) Characterisation of mesothelioma-initiating cells and their susceptibility to anti-cancer agents. PLoS One 10:e0119549. | LEAK ROUTINE OXPHOS ET | N S NS | Permeabilized cells Intact cells | Human Mouse | Endothelial;epithelial;mesothelial cell Other cell lines |
Muellebner 2015 Biomolecules | 2015 | Müllebner A, Moldzio R, Redl H, Kozlov AV, Duvigneau JC (2015) Heme degradation by heme oxygenase protects mitochondria but induces ER stress via formed bilirubin. Biomolecules 5:679-701. | OXPHOS | S | Isolated mitochondria | Rat | Liver |
Bonhoure 2015 Genes Dev | 2015 | Bonhoure N, Byrnes A, Moir RD, Hodroj W, Preitner F, Praz V, Marcelin G, Chua SC Jr, Martinez-Lopez N, Singh R, Moullan N, Auwerx J, Willemin G, Shah H, Hartil K, Vaitheesvaran B, Kurland I, Hernandez N, Willis IM1 (2015) Loss of the RNA polymerase III repressor MAF1 confers obesity resistance. Genes Dev 29:934-47. | OXPHOS | N S NS | Homogenate | Mouse | Liver |
Vincent 2015 Front Physiol | 2015 | Vincent G, Lamon S, Gant N, Vincent PJ, MacDonald JR, Markworth JF, Edge JA, Hickey AJ (2015) Changes in mitochondrial function and mitochondria associated protein expression in response to 2-weeks of high intensity interval training. Front Physiol 6:51. | LEAK OXPHOS ET | N S ROX | Permeabilized tissue | Human | Skeletal muscle |
Jeger 2015 BioMed Res Internat | 2015 | Jeger V, Brandt S, Porta F, Jakob SM, Takala J, Djafarzadeh S (2015) Dose response of Endotoxin on hepatocyte and muscle mitochondrial respiration in vitro. BioMed Res Internat Article ID 353074:1-13. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Isolated mitochondria Intact cells | Human | Skeletal muscle Liver Other cell lines |
Ehinger 2015 J Neurol | 2015 | Ehinger JK, Morota S, Hansson MJ, Paul G, Elmér E (2015) Mitochondrial dysfunction in blood cells from amyotrophic lateral sclerosis patients. J Neurol 262:1493-503. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Intact cells | Human | Blood cells Lymphocyte Platelet |
Kilbaugh 2015 Exp Neurol | 2015 | Kilbaugh TJ, Karlsson M, Byro M, Bebee A, Ralston J, Sullivan S, Duhaime AC, Hansson MJ, Elmér E, Margulies SS (2015) Mitochondrial bioenergetic alterations after focal traumatic brain injury in the immature brain. Exp Neurol 271:136-144. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized tissue Homogenate | Pig | Nervous system |
Ramos-Filho 2015 PLoS One | 2015 | Ramos-Filho D, Chicaybam G, de-Souza-Ferreira E, Guerra Martinez C, Kurtenbach E, Casimiro-Lopes G, Galina A (2015) High intensity interval training (HIIT) induces specific changes in respiration and electron leakage in the mitochondria of different rat skeletal muscles. PLoS One 10:e0131766. | LEAK OXPHOS ET | F N S Gp NS ROX | Permeabilized tissue | Rat | Skeletal muscle |
Porter 2015 Shock | 2015 | Porter C, Herndon DN, Bhattarai N, Ogunbileje JO, Szczesny B, Szabo C, Toliver-Kinsky T, Sidossis LS (2015) Severe burn injury induces thermogenically functional mitochondria in murine white adipose tissue. Shock 44:258-64. | LEAK | F N S NS Other combinations | Permeabilized tissue | Mouse | Fat |
Wahrheit 2015 Eng Life Sci | 2015 | Wahrheit J, Nonnenmacher Y, Sperber S, Heinzle E (2015) High-throughput respiration screening of single mitochondrial substrates using permeabilized CHO cells highlights control of mitochondria metabolism. Eng Life Sci 15:184-94. | LEAK OXPHOS | N S ROX | Permeabilized cells | Other mammals | Genital |
Gainutdinov 2015 Arch Biochem Biophys | 2015 | Gainutdinov T, Molkentin JD, Siemen D, Ziemer M, Debska-Vielhaber G, Vielhaber S, Gizatullina Z, Orynbayeva Z, Gellerich FN (2015) Knockout of cyclophilin D in Ppif(-/-) mice increases stability of brain mitochondria against Ca(2+) stress. Arch Biochem Biophys 579:40-6. | LEAK OXPHOS | N S ROX | Isolated mitochondria | Mouse | Nervous system |
Correa 2015 Critical Care Horizon | 2015 | Corrêa TD, Jakob SM, Takala J (2015) Mitochondrial function in sepsis. Critical Care Horizon 1:31-41 . | LEAK OXPHOS | N S CIV ROX | Isolated mitochondria | Pig | Liver |
Kelly 2015 Biotechnol J | 2015 | Kelly PS, Breen L, Gallagher C, Kelly S, Henry M, Lao NT, Meleady P, O'Gorman D, Clynes M, Barron N (2015) Re-programming CHO cell metabolism using miR-23 tips the balance towards a highly productive phenotype. Biotechnol J 10:1029-40. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Intact cells Permeabilized cells | CHO | |
Zhunussova 2015 Am J Cancer Res | 2015 | Zhunussova A, Sen B, Friedman L, Tuleukhanov S, Brooks AD, Sensenig R, Orynbayeva Z (2015) Tumor microenvironment promotes dicarboxylic acid carrier-mediated transport of succinate to fuel prostate cancer mitochondria. Am J Cancer Res 5:1665-79. | ROUTINE ET | S | Permeabilized cells Intact cells | Human Rat | Endothelial;epithelial;mesothelial cell Genital Other cell lines |
Sundstroem 2015 PhD Thesis | 2015 | Sundstrøm T (2015) Experimental modeling and novel therapeutic strategies in melanoma brain metastasis. PhD Thesis 1-146. | ET | N S NS ROX | Mouse | Nervous system | |
Karadayian 2015 Neuroscience | 2015 | Karadayian AG, Bustamante J, Czerniczyniec A, Lombardi P, Cutrera RA, Lores-Arnaiz S (2015) Alcohol hangover induces mitochondrial dysfunction and free radical production in mouse cerebellum. Neuroscience 304:47-59. | LEAK OXPHOS | N S Other combinations | Isolated mitochondria | Mouse | Nervous system |
McCommis 2015 Cell Metab | 2015 | McCommis KS, Chen Z, Fu X, McDonald WG, Colca JR, Kletzien RF, Burgess SC, Finck BN (2015) Loss of mitochondrial pyruvate carrier 2 in the liver leads to defects in gluconeogenesis and compensation via pyruvate-alanine cycling. Cell Metab 22:682-94. | OXPHOS | N S | Permeabilized cells Isolated mitochondria | Mouse | Liver |
Khera 2015 Placenta | 2015 | Khera A, Dong LF, Holland OJ, Vanderlelie J, Pasdar EA, Neuzil J, Perkins AV (2015) Selenium supplementation induces mitochondrial biogenesis in trophoblasts. Placenta 36:863-9. | LEAK ROUTINE OXPHOS ET | N S CIV | Permeabilized cells Intact cells | Human | Genital Other cell lines |
Ortiz 2015 J Pineal Res | 2015 | Ortiz F, Acuña-Castroviejo D, Doerrier C, Dayoub JC, López LC, Venegas C, García JA, López A, Volt H, Luna-Sánchez M, Escames G (2015) Melatonin blunts the mitochondrial/NLRP3 connection and protects against radiation-induced oral mucositis. J Pineal Res 58:34-49. | LEAK OXPHOS ET | N S | Homogenate Isolated mitochondria | ||
Leman 2015 Int J Biochem Cell Biol | 2015 | Leman G, Gueguen N, Desquiret-Dumas V, Kane MS, Wettervald C, Chupin S, Chevrollier A, Lebre AS, Bonnefont JP, Barth M, Amati-Bonneau P, Verny C, Henrion D, Bonneau D, Reynier P, Procaccio V (2015) Assembly defects induce oxidative stress in inherited mitochondrial complex I deficiency. Int J Biochem Cell Biol 65:91-103. | N S CIV | Permeabilized cells | Human | Endothelial;epithelial;mesothelial cell Fibroblast | |
Konopka 2015 Diabetes | 2015 | Konopka AR, Asante A, Lanza IR, Robinson MM, Johnson ML, Dalla Man C, Cobelli C, Amols MH, Irving BA, Nair KS (2015) Defects in mitochondrial efficiency and H2O2 emissions in obese women are restored to a lean phenotype with aerobic exercise training. Diabetes 64:2104-15. | LEAK OXPHOS ET | N S NS ROX | Isolated mitochondria | Human | Skeletal muscle |
Silachev 2015 Chem Biol Interact | 2015 | Silachev DN, Gulyaev MV, Zorova LD, Khailova LS, Gubsky LV, Pirogov YA, Plotnikov EY, Sukhikh GT, Zorov DB (2015) Magnetic resonance spectroscopy of the ischemic brain under lithium treatment. Link to mitochondrial disorders under stroke. Chem Biol Interact 237:175-82. | LEAK OXPHOS | S | Isolated mitochondria | Rat | Nervous system |
Skemiene 2015 FEBS J | 2015 | Skemiene K, Liobikas J, Borutaite V (2015) Anthocyanins as substrates for mitochondrial complex I - protective effect against heart ischemic injury. FEBS J 282:963-71. | LEAK OXPHOS | N S | Isolated mitochondria | Rat | Heart |
Du 2015 Aquat Toxicol | 2015 | Du X, Crawford DL, Oleksiak MF (2015) Effects of anthropogenic pollution on the oxidative phosphorylation pathway of hepatocytes from natural populations of Fundulus heteroclitus. Aquat Toxicol 165:231-40. | LEAK OXPHOS ET | N S CIV ROX | Permeabilized cells | Fishes | Liver |
Singh 2015 Free Radic Biol Med | 2015 | Singh P, Sharma R, McElhanon K, Allen CD, Megyesi JK, Beneš H, Singh SP (2015) Sulforaphane protects the heart from doxorubicin-induced toxicity. Free Radic Biol Med 86:90-101. | OXPHOS | N S CIV ROX | Permeabilized tissue | Mouse | Heart Other cell lines |
Kilbaugh 2015 PLoS One | 2015 | Kilbaugh TJ, Lvova M, Karlsson M, Zhang Z, Leipzig J, Wallace DC, Margulies SS (2015) Peripheral blood mitochondrial DNA as a biomarker of cerebral mitochondrial dysfunction following traumatic brain injury in a porcine model. PLoS One 10:e0130927. | LEAK OXPHOS | N S NS | Homogenate | Pig | Nervous system |
Senyilmaz 2015 Nature | 2015 | Senyilmaz D, Virtue S, Xu X, Tan CY, Griffin JL, Miller AK, Vidal-Puig A, Teleman AA (2015) Regulation of mitochondrial morphology and function by stearoylation of TFR1. Nature 525:124-8. | OXPHOS ET | N S CIV NS | Permeabilized tissue | Drosophila | |
Schoettl 2015 Mol Metab | 2015 | Schöttl T, Kappler L, Fromme T, Klingenspor M (2015) Limited OXPHOS capacity in white adipocytes is a hallmark of obesity in laboratory mice irrespective of the glucose tolerance status. Mol Metab 4:631-42. | LEAK ROUTINE OXPHOS ET | F N S ROX | Isolated mitochondria Intact cells | Mouse | Fat Other cell lines |
Jardim-Messeder 2015 New Phytol | 2015 | Jardim-Messeder D, Caverzan A, Rauber R, de Souza Ferreira E, Margis-Pinheiro M, Galina A (2015) Succinate dehydrogenase (mitochondrial Complex II) is a source of reactive oxygen species in plants and regulates development and stress responses. New Phytol 208:776-89. | LEAK OXPHOS | S | Isolated mitochondria | Plants | |
Zelenka 2015 Oxid Med Cell Longev | 2015 | Zelenka J, Dvořák A, Alán L (2015) L-lactate protects skin fibroblasts against aging-associated mitochondrial dysfunction via mitohormesis. Oxid Med Cell Longev 2015:351698. | LEAK ROUTINE ET | N S | Isolated mitochondria Intact cells | Rat | Liver Endothelial;epithelial;mesothelial cell Fibroblast |
Hejzlarova 2015 Biochem J | 2015 | Hejzlarová K, Kaplanová V, Nůsková H, Kovářová N, Ješina P, Drahota Z, Mráček T, Seneca S, Houštěk J (2015) Alteration of structure and function of ATP synthase and cytochrome c oxidase by lack of Fo-a and Cox3 subunits caused by mitochondrial DNA 9205delTA mutation. Biochem J 466:601-11. | LEAK OXPHOS ET | S CIV | Permeabilized cells Isolated mitochondria | Human | Other cell lines |
Arden 2015 Webvision | 2015 | Arden GB, Ramsey DJ (2015) Diabetic retinopathy and a novel treatment based on the biophysics of rod photoreceptors and dark adaptation. In: Kolb H, Fernandez E, Nelson R, eds. Webvision: The organization of the retina and visual system [Internet]. Salt Lake City (UT): University of Utah Health Sciences Center; 1995-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK310272/ | S | ||||
Beier 2015 FASEB J | 2015 | Beier UH, Angelin A, Akimova T, Wang L, Liu Y, Xiao H, Koike MA, Hancock SA, Bhatti TR, Han R, Jiao J, Veasey SC, Sims CA, Baur JA, Wallace DC, Hancock WW (2015) Essential role of mitochondrial energy metabolism in Foxp3⁺ T-regulatory cell function and allograft survival. FASEB J 29:2315-26. https://doi.org/10.1096/fj.14-268409 | LEAK OXPHOS ET | N S NS ROX | Homogenate | Mouse | Nervous system |
Maiti 2015 PhD Thesis | 2015 | Maiti P (2015) The role of caseinolytic mitochondrial matrix peptidase proteolytic subunit (CLPP) in regulation of mitochondrial ribosome biogenesis in mammals. PhD Thesis 1-120. | LEAK OXPHOS ET | N S NS ROX | Isolated mitochondria | Mouse | Heart |
Singh 2015 Biochim Biophys Acta | 2015 | Singh F, Charles AL, Schlagowski AI, Bouitbir J, Bonifacio A, Piquard F, Krähenbühl S, Geny B, Zoll J (2015) Reductive stress impairs myoblasts mitochondrial function and triggers mitochondrial hormesis. Biochim Biophys Acta 1853:1574-85. | LEAK OXPHOS | N S NS | Permeabilized tissue | Mouse | Skeletal muscle |
Porter 2015 Med Sci Sports Exerc | 2015 | Porter C, Reidy PT, Bhattarai N, Sidossis LS, Rasmussen BB (2015) Resistance exercise training alters mitochondrial function in human skeletal muscle. Med Sci Sports Exerc 47:1922-31. | LEAK OXPHOS ET | N S NS | Permeabilized tissue | Human | Skeletal muscle |
Ziak 2015 Mitochondrion | 2015 | Ziak J, Krajcova A, Jiroutkova K, Nemcova V, Dzupa V, Duska F (2015) Assessing the function of mitochondria in cytosolic context in human skeletal muscle: Adopting high-resolution respirometry to homogenate of needle biopsy tissue samples. Mitochondrion 21:106-12. | LEAK OXPHOS ET | N S NS ROX | Homogenate Isolated mitochondria | Human | Skeletal muscle |
Schoettl 2015 Endocrinology | 2015 | Schöttl T, Kappler L, Braun K, Fromme T, Klingenspor M (2015) Limited mitochondrial capacity of visceral versus subcutaneous white adipocytes in male C57BL/6N mice. Endocrinology 156:923-33. | LEAK ROUTINE OXPHOS ET | N S ROX | Permeabilized cells Isolated mitochondria Intact cells | Mouse | Fat |
Joergensen 2015 J Cereb Blood Flow Metab | 2015 | Jørgensen T, Grunnet N, Quistorff B (2015) One-year high fat diet affects muscle-but not brain mitochondria. J Cereb Blood Flow Metab 35:943-50. | LEAK OXPHOS | F N S Other combinations | Isolated mitochondria | Rat | Skeletal muscle Nervous system |
Wang 2015 Nat Commun | 2015 | Wang Y, Oxer D, Hekimi S (2015) Mitochondrial function and lifespan of mice with controlled ubiquinone biosynthesis. Nat Commun 6:6393. | LEAK OXPHOS | N S | Isolated mitochondria | Mouse | Heart Skeletal muscle Kidney |
Truksa 2015 Antioxid Redox Signal | 2015 | Truksa J, Dong L, Rohlena J, Stursa J, Vondrusova M, Goodwin J, Nguyen M, Kluckova K, Rychtarcikova Z, Lettlova S, Spacilova J, Stapelberg M, Zoratti M, Neuzil J (2015) Mitochondrially targeted vitamin E succinate modulates expression of mitochondrial DNA transcripts and mitochondrial biogenesis. Antioxid Redox Signal 22:883-900. | ROUTINE | S | Intact cells | Human Mouse | Genital Other cell lines |
Chausse 2015 PLoS One | 2015 | Chausse B, Vieira-Lara MA, Sanchez AB, Medeiros MH, Kowaltowski AJ (2015) Intermittent fasting results in tissue-specific changes in bioenergetics and redox state. PLoS One 10:e0120413. | LEAK OXPHOS | N S CIV | Isolated mitochondria | Rat | Heart Skeletal muscle Nervous system Liver |
Lark 2015 Front Physiol | 2015 | Lark DS, Reese LR, Ryan TE, Torres MJ, Smith CD, Lin CT, Neufer PD (2015) Protein kinase A governs oxidative phosphorylation kinetics and oxidant emitting potential at complex I. https://doi.org/10.3389/fphys.2015.00332 | LEAK ET OXPHOS | N S | Permeabilized tissue Isolated mitochondria | Mouse | Skeletal muscle Liver |
Irving 2015 J Clin Endocrinol Metab | 2015 | Irving BA, Lanza IR, Henderson GC, Rao RR, Spiegelman BM, Nair KS (2015) Combined training enhances skeletal muscle mitochondrial oxidative capacity independent of age. J Clin Endocrinol Metab 100:1654-63. | LEAK OXPHOS ET | N S NS | Isolated mitochondria | Human | Skeletal muscle |
Kluckova 2015 Methods Mol Biol | 2015 | Kluckova K, Dong L, Bajzikova M, Rohlena J, Neuzil J (2015) Evaluation of respiration of mitochondria in cancer cells exposed to mitochondria-targeted agents. Methods Mol Biol 1265:181-94. | LEAK OXPHOS ET | N S NS ROX | Permeabilized cells Homogenate Intact cells | Mouse | Endothelial;epithelial;mesothelial cell Genital Other cell lines |
Aroor 2015 Diabetes | 2015 | Aroor AR, Habibi J, Ford DA, Nistala R, Lastra G, Manrique C, Dunham MM, Ford KD, Thyfault JP, Parks EJ, Sowers JR, Rector RS (2015) Dipeptidyl peptidase-4 inhibition ameliorates western diet-induced hepatic steatosis and insulin resistance through hepatic lipid remodeling and modulation of hepatic mitochondrial function. Diabetes 64:1988-2001. | LEAK ROUTINE OXPHOS ET | F N S NS | Isolated mitochondria | Mouse | Liver |
Ping 2015 Oxid Med Cell Longev | 2015 | Ping Z, Zhang LF, Cui YJ, Chang YM, Jiang CW, Meng ZZ, Xu P, Liu HY, Wang DY, Cao XB (2015) The protective effects of Salidroside from exhaustive exercise-induced heart injury by enhancing the PGC-1𝛼–NRF1/NRF2 pathway and mitochondrial respiratory function in rats. Oxid Med Cell Longev Article ID 876825. | OXPHOS ET | N S CIV ROX | Permeabilized tissue | Rat | Heart |
Abou-Hamdan 2015 Methods Enzymol | 2015 | Abou-Hamdan A, Guedouari-Bounihi H, Lenoir V, Andriamihaja M, Blachier F, Bouillaud F (2015) Oxidation of H2S in mammalian cells and mitochondria. Methods Enzymol 554:201-28. | OXPHOS | N S CIV | Intact cells Homogenate Isolated mitochondria | Human Pig Mouse Rat | Heart Nervous system Liver Kidney Genital CHO Neuroblastoma Fibroblast |
Christiansen 2015 J Vet Med Sci | 2015 | Christiansen LB, Dela F, Koch J, Yokota T (2015) Tissue-specific and substrate-specific mitochondrial bioenergetics in feline cardiac and skeletal muscles. J Vet Med Sci 77:669-75. | LEAK OXPHOS ET | F N S CIV NS Other combinations ROX | Permeabilized tissue | Cat | Heart Skeletal muscle |
Iftikar 2015 Comp Biochem Physiol A Mol Integr Physiol | 2015 | Iftikar FI, Morash AJ, Cook DG, Herbert NA, Hickey AJ (2015) Temperature acclimation of mitochondria function from the hearts of a temperate wrasse (Notolabrus celidotus). Comp Biochem Physiol A Mol Integr Physiol 184:46-55. | LEAK OXPHOS ET | N S CIV NS ROX | Permeabilized tissue | Fishes | Heart |
Mourier 2015 J Cell Biol | 2015 | Mourier A, Motori E, Brandt T, Lagouge M, Atanassov I, Galinier A, Rappl G, Brodesser S, Hultenby K, Dieterich C, Larsson NG (2015) Mitofusin 2 is required to maintain mitochondrial coenzyme Q levels. J Cell Biol 208:429-42. | LEAK OXPHOS ET | N S Gp Other combinations | Permeabilized cells Isolated mitochondria | Mouse | Heart Fibroblast |
Wuest 2015 J Physiol | 2015 | Wüst RC, Helmes M, Stienen GJ (2015) Rapid changes in NADH and flavin autofluorescence in rat cardiac trabeculae reveal large mitochondrial complex II reserve capacity. J Physiol 593:1829-40. | LEAK OXPHOS | N S NS ROX | Permeabilized tissue | Rat | Heart |
Hendricks 2015 Thesis | 2015 | Hendricks EW (2015) The impact of aging and estrogen therapy on synaptic mitochondrial bioenergetics in an Alzheimer's mouse model. Master Thesis 1-67. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Isolated mitochondria Intact cells | Mouse | Nervous system |
Cell ergometry | 2015 | Gnaiger E (2015) Cell ergometry and OXPHOS. Mitochondr Physiol Network 2015-01-18. | LEAK OXPHOS ET | N S NS ROX | |||
Chu 2015 Liver Transpl | 2015 | Chu MJ, Hickey AJ, Jiang Y, Petzer A, Bartlett AS, Phillips AR (2015) Mitochondrial dysfunction in steatotic rat livers occurs because a defect in complex I makes the liver susceptible to prolonged cold ischemia. Liver Transpl 21:396-407. | LEAK OXPHOS ET | N S ROX | Homogenate | Rat | Liver |
Kake-Guena 2015 J Exp Zool A Ecol Genet Physiol | 2015 | Kake-Guena SA, Touisse K, Vergilino R, Dufresne F, Blier PU, Lemieux H1 (2015) Assessment of mitochondrial functions in Daphnia pulex clones using high-resolution respirometry. J Exp Zool A Ecol Genet Physiol 323:292-300. | LEAK OXPHOS | N S CIV NS ROX | Permeabilized tissue | Crustaceans | |
Wessels 2015 Diabetes Obes Metab | 2015 | Wessels B, Ciapaite J, van den Broek NM, Houten SM, Nicolay K, Prompers JJ (2015) Pioglitazone treatment restores in vivo muscle oxidative capacity in a rat model of diabetes. Diabetes Obes Metab 17:52-60. | LEAK OXPHOS ET | F N S | Isolated mitochondria | Rat | Skeletal muscle |
Drechsler 2015 Intensive Care Medicine Experimental | 2015 | Drechsler S, Weixelbaumer KM, Weidinger A, Raeven P, Khadem A, Redl H, van Griensven M, Bahrami S, Remick D, Kozlov A, Osuchowski MF (2015) Why do they die? Comparison of selected aspects of organ injury and dysfunction in mice surviving and dying in acute abdominal sepsis. Intensive Care Medicine Experimental 3:12. | LEAK OXPHOS ET | N S | Homogenate | Mouse | Liver Kidney |
Nelson 2015 Master Thesis | 2015 | Nelson MB (2015) The role of receptors for advanced glycation end-products (RAGE) and ceramide in cardiovascular disease. Master Thesis 1-53. | LEAK OXPHOS ET | N S NS | Permeabilized cells Permeabilized tissue | Mouse Rat | Heart Other cell lines |
Herbst 2015 J Physiol | 2015 | Herbst EA, Holloway GP (2015) Permeabilization of brain tissue in situ enables multi-region analysis of mitochondrial function in a single mouse brain. J Physiol 593:787-801. | LEAK OXPHOS | N S NS | Permeabilized tissue Isolated mitochondria | Mouse | Nervous system |
Makrecka-Kuka 2015 Biomolecules | 2015 | Makrecka-Kuka M, Krumschnabel G, Gnaiger E (2015) High-resolution respirometry for simultaneous measurement of oxygen and hydrogen peroxide fluxes in permeabilized cells, tissue homogenate and isolated mitochondria. https://doi.org/10.3390/biom5031319 | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Homogenate Isolated mitochondria Intact cells | Human Mouse | Heart Nervous system HEK |
Hagl 2015 J Alzheimers Dis | 2015 | Hagl S, Grewal R, Ciobanu I, Helal A, Khayyal MT, Muller WE, Eckert GP (2015) Rice bran extract compensates mitochondrial dysfunction in a cellular model of early Alzheimer’s disease. J Alzheimers Dis 43:927-38. | LEAK OXPHOS ET | N S CIV NS ROX | Permeabilized cells | Rat | Nervous system Kidney Other cell lines |
Krumschnabel 2015 Methods Mol Biol | 2015 | Krumschnabel G, Fontana-Ayoub M, Sumbalova Z, Heidler J, Gauper K, Fasching M, Gnaiger E (2015) Simultaneous high-resolution measurement of mitochondrial respiration and hydrogen peroxide production. Methods Mol Biol 1264:245-61. | LEAK OXPHOS ET | N S NS ROX | Isolated mitochondria | Mouse | Nervous system |
Grabez 2015 J Anim Sci | 2015 | Grabež V, Kathri M, Phung V, Moe KM, Slinde E, Skaugen M, Saarem K, Egelandsdal B (2015) Protein expression and oxygen consumption rate of early postmortem mitochondria relate to meat tenderness. J Anim Sci 93:1967-79. | LEAK OXPHOS ET | F N S NS Other combinations ROX | Permeabilized tissue | Bovines | Skeletal muscle |
Hansson 2015 Eur J Pharmacol | 2015 | Hansson MJ, Llwyd O, Morin D, de Paulis D, Arnoux T, Gouarné C, Koul S, Engblom H, Bordet T, Tissier R, Arheden H, Erlinge D, Halestrap AP, Berdeaux A, Pruss RM, Schaller S (2015) Differences in the profile of protection afforded by TRO40303 and mild hypothermia in models of cardiac ischemia/reperfusion injury. Eur J Pharmacol 760:7-19. | LEAK OXPHOS ET | N S NS | Permeabilized tissue | Pig | Heart |
Richman 2015 PLoS Genet | 2015 | Richman TR, Ermer JA, Davies SM, Perks KL, Viola HM, Shearwood AM, Hool LC, Rackham O, Filipovska A (2015) Mutation in MRPS34 compromises protein synthesis and causes mitochondrial dysfunction. PLoS Genet 11:e1005089. | LEAK OXPHOS | N S CIV | Isolated mitochondria | Mouse | Heart Liver |
Hasli 2015 Master Thesis | 2015 | Hasli PR (2015) Characterization of mitochondrial respiration and quality differences in diploid and triploid Atlantic salmon (Salmo salar L.) at 5 °C, 10 °C and 15 °C. Master Thesis:1-147. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue Homogenate | Fishes | Heart Skeletal muscle |
Tan 2015 Cell Metab | 2015 | Tan AS, Baty JW, Dong L, Bezawork-Geleta A, Endaya B, Goodwin J, Bajzikova M, Kovarova J, Peterka M, Yan B, Pesdar EA, Sobol M, Filimonenko A, Stuart S, Vondrusova M, Kluckova K, Sachaphibulkij K, Rohlena J, Hozak P, Truksa J, Eccles D, Haupt LM, Griffiths LR, Neuzil J, Berridge MV (2015) Mitochondrial genome acquisition restores respiratory function and tumorigenic potential of cancer cells without mitochondrial DNA. Cell Metab 21:81-94. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Isolated mitochondria Intact cells | Human Mouse | Endothelial;epithelial;mesothelial cell Genital Other cell lines |
Caito 2015 Antioxid Redox Signal | 2015 | Caito SW, Aschner M (2015) Mitochondrial redox dysfunction and environmental exposures. Antioxid Redox Signal 23:578-95. | OXPHOS | N S CIV | Isolated mitochondria | Human Mouse Rat Bovines Drosophila Fishes Hexapods | Heart Nervous system Liver Kidney Lung;gill Endothelial;epithelial;mesothelial cell |
Schrauwen-Hinderling 2015 Antioxid Redox Signal | 2015 | Schrauwen-Hinderling VB, Kooi ME, Schrauwen P (2015) Mitochondrial function and diabetes; consequences for skeletal and cardiac muscle metabolism. Antioxid Redox Signal 24:39-51. | LEAK OXPHOS | F N S CIV | Permeabilized tissue Isolated mitochondria | Human | Heart Skeletal muscle |
Soares 2015 PLoS One | 2015 | Soares JB, Gaviraghi A, Oliveira MF (2015) Mitochondrial physiology in the major arbovirus vector Aedes aegypti: substrate preferences and sexual differences define respiratory capacity and superoxide production. PLoS One 10:e0120600. | LEAK OXPHOS ET | N S Gp NS Other combinations ROX | Permeabilized tissue Isolated mitochondria | Hexapods | Skeletal muscle |
Lim 2015 Am J Cancer Res | 2015 | Lim SC, Carey KT, McKenzie M (2015) Anti-cancer analogues ME-143 and ME-344 exert toxicity by directly inhibiting mitochondrial NADH: ubiquinone oxidoreductase (Complex I). Am J Cancer Res 5:689-701. | LEAK ROUTINE OXPHOS | N S | Permeabilized cells Isolated mitochondria Intact cells | Human | Kidney Other cell lines HEK HeLa Fibroblast |
Christiansen 2015 Am J Physiol Heart Circ Physiol | 2015 | Christiansen LB, Dela F, Koch J, Hansen CN, Leifsson PS, Yokota T (2015) Impaired cardiac mitochondrial oxidative phosphorylation and enhanced mitochondrial oxidative stress in feline hypertrophic cardiomyopathy. Am J Physiol Heart Circ Physiol 308:H1237-47. | LEAK OXPHOS ET | F N S CIV NS ROX | Permeabilized tissue Isolated mitochondria | Cat | Heart Skeletal muscle |
Melo Hanchuk 2015 Cell Signal | 2015 | Melo Hanchuk TD, Papa PF, La Guardia PG, Vercesi AE, Kobarg J (2015) Nek5 interacts with mitochondrial proteins and interferes negatively in mitochondrial mediated cell death and respiration. Cell Signal 27:1168-77. | LEAK OXPHOS | N S CIV ROX | Permeabilized cells | Human | HEK |
Flatters 2015 Prog Mol Biol Transl Sci | 2015 | Flatters SJ (2015) The contribution of mitochondria to sensory processing and pain. Prog Mol Biol Transl Sci 131:119-46. | OXPHOS ET | N S CIV NS | Homogenate Isolated mitochondria | Rat | Nervous system |
Miwa 2015 Free Radic Biol Med | 2015 | Miwa S, Treumann A, Bell A, Vistoli G, Nelson G, Hay S, von Zglinicki T (2015) Carboxylesterase converts Amplex red to resorufin: Implications for mitochondrial H2O2 release assays. Free Radic Biol Med 90:173-83. | LEAK OXPHOS ET | N S ROX | Isolated mitochondria | Mouse | Liver |
Crombie 2015 Biochem Biophys Rep | 2015 | Crombie DE, van Bergena N, Davidsona KC, Anjomani Virmounib S, Mckelviec PA, Chrysostomoua V, Conquesta A, Corbend LA, Pookb MA, Kulkarnia T, Trouncea IA, Peraf MF, Delatyckid MB, Pébaya A (2015) Characterization of the retinal pigment epithelium in Friedreich ataxia. Biochem Biophys Rep 4:141–7. | LEAK OXPHOS ET | N S NS ROX | Permeabilized cells | Human | Nervous system Endothelial;epithelial;mesothelial cell Stem cells |
Assmann 2014 PhD Thesis | 2015 | Assmann N (2015) Impact of Fanconi-associated protein on the mitochonrial proteome. PhD Thesis 1-111. | LEAK ROUTINE OXPHOS ET | F N S CIV NS ROX | Permeabilized cells Intact cells | Pig | Kidney Other cell lines |
Lauritzen 2015 Am J Physiol Heart Circ Physiol | 2015 | Lauritzen KH, Kleppa L, Aronsen JM, Eide L, Carlsen H, Haugen ØP, Sjaastad I, Klungland A, Rasmussen LJ, Attramadal H, Storm-Mathisen J, Bergersen LH (2015) Impaired dynamics and function of mitochondria caused by mtDNA toxicity leads to heart failure. Am J Physiol Heart Circ Physiol 309:H434-49. | S | Homogenate | Mouse | Heart | |
Hals 2015 PLoS One | 2015 | Hals IK, Bruerberg SG, Ma Z, Scholz H, Björklund A, Grill V (2015) Mitochondrial respiration in insulin-producing β-cells: general characteristics and adaptive effects of hypoxia. PLoS One 10:e0138558. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Rat | Islet cell;pancreas;thymus Other cell lines |
Antoun 2015 JIMD Rep | 2015 | Antoun G, McBride S, Vanstone JR, Naas T, Michaud J, Redpath S, McMillan HJ, Brophy J, Daoud H, Chakraborty P, Dyment D, Holcik M, Harper ME, Lines MA (2015) Detailed biochemical and bioenergetic characterization of FBXL4-related encephalomyopathic mitochondrial DNA depletion. JIMD Rep 27:1-9. | LEAK OXPHOS ET | F N S CIV NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Valet 2015 US Patent | 2015 | Valet P, Dray C, Knauf C, Kunduzova O, Castan-Laurell I (2015) Pharmaceutical composition for use in the treatment of dysfunction associated with aging. US Patent US20150290286 A1. | OXPHOS | N S | Permeabilized tissue | Mouse | Skeletal muscle |
Burtscher 2015 Mitochondrion | 2015 | Burtscher J, Zangrandi L, Schwarzer C, Gnaiger E (2015) Differences in mitochondrial function in homogenated samples from healthy and epileptic specific brain tissues revealed by high-resolution respirometry. Mitochondrion 25:104-12. | LEAK OXPHOS ET | N S CIV NS ROX | Permeabilized tissue Homogenate | Mouse | Nervous system |
Herbst 2015 Neuroscience | 2015 | Herbst EA, Holloway GP (2015) Exercise training normalizes mitochondrial respiratory capacity within the striatum of the R6/1 model of Huntington's disease. Neuroscience 303:515-23. | OXPHOS | N S NS | Permeabilized tissue | Mouse | Nervous system |
Weidinger 2015 Antioxid Redox Signal | 2015 | Weidinger A, Müllebner A, Paier-Pourani J, Banerjee A*, Miller I, Lauterböck L, Duvigneau JC, Skulachev VP, Redl H, Kozlov AV (2015) Vicious inducible nitric oxide synthase-mitochondrial reactive oxygen species cycle accelerates inflammatory response and causes liver injury in rats. Antioxid Redox Signal 22:572-86. | LEAK OXPHOS ET | N S | Homogenate | Rat | Liver |
Schirris 2015 Cell Metab | 2015 | Schirris TJ, Renkema GH, Ritschel T, Voermans NC, Bilos A, van Engelen BG, Brandt U, Koopman WJ, Beyrath JD, Rodenburg RJ, Willems PH, Smeitink JA, Russel FG (2015) Statin-induced myopathy is associated with mitochondrial complex III inhibition. Cell Metab 22:399-407. | ROUTINE OXPHOS ET | N S Gp CIV NS ROX | Permeabilized cells | Human Mouse | Skeletal muscle Other cell lines |
Gnaiger 2015 Scand J Med Sci Sports | 2015 | Gnaiger E, Boushel R, Søndergaard H, Munch-Andersen T, Damsgaard R, Hagen C, Díez-Sánchez C, Ara I, Wright-Paradis C, Schrauwen P, Hesselink M, Calbet JAL, Christiansen M, Helge JW, Saltin B (2015) Mitochondrial coupling and capacity of oxidative phosphorylation in skeletal muscle of Inuit and caucasians in the arctic winter. https://doi.org/10.1111/sms.12612 | LEAK OXPHOS ET | F N S ROX | Permeabilized tissue | Human | Skeletal muscle |
Kucera 2015 Oxid Med Cell Longev | 2015 | Kucera O, Mezera V, Moravcova A, Endlicher R, Lotkova H, Drahota Z, Cervinkova Z (2015) In vitro toxicity of epigallocatechin gallate in rat liver mitochondria and hepatocytes. Oxid Med Cell Longev 2015:476180. | LEAK OXPHOS | N S | Isolated mitochondria Intact cells | Rat | Liver |
Boushel 2015 Scand J Med Sci Sports | 2015 | Boushel R, Gnaiger E, Larsen FJ, Helge JW, Gonzalez-Alonso J, Ara I, Munch-Andersen T, van Hall G, Søndergaard H, Saltin B, Calbet JAL (2015) Maintained peak leg and pulmonary VO2 despite substantial reduction in muscle mitochondrial capacity. Scand J Med Sci Sports 25 (Suppl 4):135–43. | OXPHOS | F N S NS | Intact organ Permeabilized tissue | Human | Skeletal muscle |
Sobotka 2015 Physiol Res | 2015 | Sobotka O, Drahota Z, Kučera O, Endlicher R, Rauchová H, Červinková Z (2015) The effect of α-tocopheryl succinate on succinate respiration in rat liver mitochondria. Physiol Res 64 Suppl 5:S609-15. | OXPHOS ET | S | Permeabilized cells Homogenate Isolated mitochondria | Rat | Liver |
Kruse 2015 Aging Cell | 2015 | Kruse SE, Karunadharma PP, Basisty N, Johnson R, Beyer RP, MacCoss MJ, Rabinovitch PS, Marcinek DJ (2015) Age modifies respiratory complex I and protein homeostasis in a muscle type-specific manner. Aging Cell 15:89-99. | LEAK OXPHOS ET | N S CIV NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
Paeaesuke 2015 Oxid Med Cell Longev | 2015 | Pääsuke R, Eimre M, Piirsoo A, Peet N, Laada L, Kadaja L, Roosimaa M, Pääsuke M, Märtson A, Seppet E, Paju K (2015) Proliferation of human primary myoblasts is associated with altered energy metabolism in dependence of ageing in vivo and in vitro. Oxid Med Cell Longev 8296150:10p. | OXPHOS | N S CIV ROX | Permeabilized cells | Human | Skeletal muscle |
Clemens 2015 Brain | 2015 | Clemens LE, Weber JJ, Wlodkowski TT, Yu-Taeger L, Michaud M, Calaminus C, Eckert SH, Gaca J, Weiss A, Magg JC, Jansson EK, Eckert GP, Pichler BJ, Bordet T, Pruss RM, Riess O, Nguyen HP (2015) Olesoxime suppresses calpain activation and mutant huntingtin fragmentation in the BACHD rat. Brain 138:3632-53. | LEAK OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Rat | Nervous system |
Rodrigues 2016 Biochem J | 2015 | Rodrigues MF, Obre E, Melo FH, Santos-Jr GC, Galina A, Jasiulionis MG, Rossignol R, Rumjanek FD, Amoedo ND (2016) Enhanced OXPHOS, glutaminolysis and beta-oxidation constitute the metastatic phenotype of melanoma cells. https://doi.org/10.1042/BJ20150645 | LEAK ROUTINE OXPHOS ET | F N S ROX | Permeabilized cells Intact cells | Mouse | Endothelial;epithelial;mesothelial cell Other cell lines |
Kang 2015 Int J Clin Exp Med | 2015 | Kang M, Zhao L, Ren M, Deng M, Li C (2015) Reduced metallothionein expression induced by Zinc deficiency results in apoptosis in hepatic stellate cell line LX-2. Int J Clin Exp Med 8:20603-9. | LEAK OXPHOS | S | Isolated mitochondria | Human | Liver Other cell lines |
Jiroutkova 2015 Crit Care | 2015 | Jiroutková K, Krajčová A, Ziak J, Fric M, Waldauf P, Džupa V, Gojda J, Němcova-Fürstová V, Kovář J, Elkalaf M, Trnka J, Duška F (2015) Mitochondrial function in skeletal muscle of patients with protracted critical illness and ICU-acquired weakness. Crit Care 19:448. | LEAK OXPHOS ET | N S Gp CIV NS Other combinations ROX | Homogenate | Human | Skeletal muscle |
Gram 2015 J Physiol | 2015 | Gram M, Vigelsø A, Yokota T, Helge JW, Dela F, Hey-Mogensen M (2015) Skeletal muscle mitochondrial H2O2 emission increases with immobilization and decreases after aerobic training in young and older men. J Physiol 593:4011-27. | LEAK OXPHOS | N S | Isolated mitochondria | Human | Skeletal muscle |
Darrah-Wiedemeier 2015 Graduate Theses and Dissertations | 2015 | Darrah-Wiedemeier KL (2015) The physiological effects of the seed treatment Stamina on maize seedling length, ADP:O ratios, and respiration rates. Graduate Theses and Dissertations Paper 14673:55 pp. | LEAK OXPHOS | S | Isolated mitochondria | Plants | |
Hey-Mogensen 2015 J Physiol | 2015 | Hey-Mogensen M, Gram M, Jensen MB, Lund MT, Hansen CN, Scheibye-Knudsen M, Bohr VA, Dela F (2015) A novel method for determining human ex vivo submaximal skeletal muscle mitochondrial function. J Physiol 593:3991-4010. | LEAK OXPHOS | N S | Isolated mitochondria | Human | Skeletal muscle |
Angebault 2015 Am J Hum Genet | 2015 | Angebault C, Guichet PO, Talmat-Amar Y, Charif M, Gerber S, Fares-Taie L, Gueguen N, Halloy F, Moore D, Amati-Bonneau P, Manes G, Hebrard M, Bocquet B, Quiles M, Piro-Mégy C, Teigell M, Delettre C, Rossel M, Meunier I, Preising M, Lorenz B, Carelli V, Chinnery PF, Yu-Wai-Man P, Kaplan J, Roubertie A, Barakat A, Bonneau D, Reynier P, Rozet JM, Bomont P, Hamel CP, Lenaers G (2015) Recessive mutations in RTN4IP1 cause isolated and syndromic optic neuropathies. Am J Hum Genet 97:754-60. | N S CIV NS ROX | Human | Endothelial;epithelial;mesothelial cell Fibroblast | ||
Baris 2015 Am J Physiol Regul Integr Comp Physiol | 2015 | Baris TZ, Crawford DL, Oleksiak MF (2015) Acclimation and acute temperature effects on population differences in oxidative phosphorylation. Am J Physiol Regul Integr Comp Physiol 310:R185-96. | LEAK OXPHOS ET | N S CIV NS Other combinations ROX | Permeabilized tissue | Fishes | Heart |
Hollis 2015 Proc Natl Acad Sci U S A | 2015 | Hollis F, van der Kooij MA, Zanoletti O, Lozano L, Cantó C, Sandi C (2015) Mitochondrial function in the brain links anxiety with social subordination. Proc Natl Acad Sci U S A 112:15486-91. | OXPHOS ET | N S NS ROX | Homogenate | Rat | Nervous system |
Fliri 2015 US Patent | 2015 | Fliri HG, Ford RL, Scowen DA, Batcheller DG, Ehinger J, Elmér E, Hansson MJ, Sjövall F (2015) Protected succinates for enhancing mitochondrial atp-production. US Patent US20150259317 A1. | ET | S NS ROX | Permeabilized cells Intact cells | Human | Blood cells Platelet |
Chekulayev 2015 Biochem Biophys Rep | 2015 | Chekulayev V, Mado K, Shevchuk I, Koit A, Kaldma A, Klepinin A, Timohhina N, Tepp K, Kandashvili M, Ounpuu L, Heck K, Truu L, Planken A, Valvere V, Kaambre T (2015) Metabolic remodeling in human colorectal cancer and surrounding tissues: alterations in regulation of mitochondrial respiration and metabolic fluxes. Biochem Biophys Rep 4:111-25. | OXPHOS | N S CIV ROX | Permeabilized tissue | Human | Endothelial;epithelial;mesothelial cell |
Banh 2015 Comp Biochem Physiol B Biochem Mol Biol | 2015 | Banh S, Wiens L, Sotiri E, Treberg JR (2015) Mitochondrial reactive oxygen species production by fish muscle mitochondria: Potential role in acute heat-induced oxidative stress. Comp Biochem Physiol B Biochem Mol Biol 191:99-107. | LEAK OXPHOS | S | Isolated mitochondria | Rat Fishes | Skeletal muscle |
Morato 2015 Cell Death Differ | 2015 | Morató L, Ruiz M, Boada J, Calingasan NY, Galino J, Guilera C, Jové M, Naudí A, Ferrer I, Pamplona R, Serrano M, Portero-Otín M, Beal MF, Fourcade S, Pujol A (2015) Activation of sirtuin 1 as therapy for the peroxisomal disease adrenoleukodystrophy. Cell Death Differ 22:1742-53. | LEAK OXPHOS | N S NS ROX | Permeabilized tissue | Mouse | Nervous system |
Patil 2015 J Nutr Biochem | 2015 | Patil YN, Dille KN, Burk DH, Cortez CC, Gettys TW (2015) Cellular and molecular remodeling of inguinal adipose tissue mitochondria by dietary methionine restriction. J Nutr Biochem 26:1235-47. | LEAK OXPHOS ET | F N S Gp ROX | Isolated mitochondria | Mouse | Skeletal muscle Liver Fat |
Tomsik 2015 J Organomet Chem | 2015 | Tomsík P, Muthna D, Rezacova M, Micuda S, Cmielova J, Hroch M, Endlicher R, Cervinkova Z, Rudolf E, Hann S, Stíbal D, Therrien B, Süss-Fink G (2015) [(p-MeC6H4Pri)2Ru2(SC6H4-p-But)3]Cl (diruthenium-1), a dinuclear arene ruthenium compound with very high anticancer activity: An in vitro and in vivo study. J Organomet Chem 782:42-51. | LEAK OXPHOS | N S | Isolated mitochondria | Rat | Liver |
Harris 2015 Diabetes | 2015 | Harris LA, Skinner JR, Shew TM, Pietka TA, Abumrad NA, Wolins NE (2015) Perilipin 5-driven lipid droplet accumulation in skeletal muscle stimulates the expression of fibroblast growth factor 21. Diabetes 64:2757-68. | OXPHOS ET | N S NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
Chin 2015 US Patent | 2015 | Chin MT, Chien WM, Dinca A (2015) Modified tafazzin proteins and methods of making and using the same. US Patent US20150203827 A1. | OXPHOS | N S CIV | Permeabilized tissue | Mouse | Skeletal muscle |
Sjoevall 2015 US Patent | 2015 | Sjövall F, Ehinger J, Hansson M, Elmer E, Batcheller DG (2018) Mitochondrial toxicity test. US Patent US20150253306 A1. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Intact cells Permeabilized cells | Human | Blood cells Macrophage-derived Platelet |
Duicu 2015 Biomed Res Int | 2015 | Duicu OM, Lighezan R, Sturza A, Ceausu RA, Borza C, Vaduva A, Noveanu L, Gaspar M, Ionac A, Feier H, Muntean DM, Mornos C (2015) Monoamine oxidases as potential contributors to oxidative stress in diabetes: time for a study in patients undergoing heart surgery. Biomed Res Int 2015:515437. | LEAK OXPHOS ET | N S ROX | Permeabilized tissue | Human | Heart |
Houben 2015 Mitochondrion | 2015 | Houben R, Leleu C, Fraipont A, Serteyn D, Votion DM (2015) Determination of muscle mitochondrial respiratory capacity in Standardbred racehorses as an aid to predicting exertional rhabdomyolysis. Mitochondrion 24:99-104. | OXPHOS ET | N S NS ROX | Permeabilized tissue | Horse | Skeletal muscle |
Imran 2015 J Neurochem | 2015 | Imran I, Hillert MH, Klein J (2015) Early metabolic responses to lithium/pilocarpine-induced status epilepticus in rat brain. J Neurochem 135:1007-18. | LEAK OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Rat | Nervous system |
Teh 2015 Oncogene | 2015 | Teh JT, Zhu WL, Ilkayeva OR, Li Y, Gooding J, Casey PJ, Summers SA, Newgard CB, Wang M (2015) Isoprenylcysteine carboxylmethyltransferase regulates mitochondrial respiration and cancer cell metabolism. Oncogene 34:3296-304. | OXPHOS | N S DQ CIV ROX | Permeabilized cells | Human | Other cell lines |
Cahill 2015 J Biol Chem | 2015 | Cahill TJ, Leo V, Kelly M, Stockenhuber A, Kennedy NW, Bao L, Cereghetti G, Harper AR, Czibik G, Lao C, Bellahcene M, Steeples V, Ghaffari S, Yavari A, Mayer A, Poulton J, Ferguson D, Scorrano L, Hettiarachchi NT, Peers C, Boyle J, Hill RB, Simmons A, Watkins H, Dear TN, Ashrafian H (2015) Resistance of dynamin-related protein 1 oligomers to disassembly impairs mitophagy resulting in myocardial inflammation and heart failure. J Biol Chem 290:25907-19. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Mouse | Heart |
Errea 2015 J Neuroinflammation | 2015 | Errea O, Moreno B, Gonzalez-Franquesa A, Garcia-Roves PM, Villoslada P (2015) The disruption of mitochondrial axonal transport is an early event in neuroinflammation. J Neuroinflammation 12:152. | LEAK OXPHOS ET | N S CIV NS ROX | Homogenate | Mouse | Nervous system |
Hagl 2015 Molecules | 2015 | Hagl S, Berressem D, Bruns B, Sus N, Frank J, Eckert GP (2015) Beneficial Effects of Ethanolic and Hexanic Rice Bran Extract on Mitochondrial Function in PC12 Cells and the Search for Bioactive Components. Molecules 20(9):16524-39. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells | Rat | Nervous system Other cell lines |
Hagl 2015 Neurochem Int | 2015 | Hagl S, Kocher A, Schiborr C, Kolesova N, Frank J, Eckert GP (2015) Curcumin micelles improve mitochondrial function in neuronal PC12 cells and brains of NMRI mice - Impact on bioavailability. Neurochem Int 89:234-42. | LEAK OXPHOS ET | N S CIV | Isolated mitochondria | Mouse | Nervous system |
Kilbaugh 2015 J Am Heart Assoc | 2015 | Kilbaugh TJ, Sutton RM, Karlsson M, Hansson MJ, Naim MY, Morgan RW, Bratinov G, Lampe JW, Nadkarni VM, Becker LB, Margulies SS, Berg RA (2015) Persistently altered brain mitochondrial bioenergetics after apparently successful resuscitation from cardiac arrest. J Am Heart Assoc 4(9) pii: e002232. | LEAK OXPHOS ET | N S CIV NS ROX | Homogenate | Pig | Nervous system |
Diana 2015 Surg Innov | 2015 | Diana M, Noll E, Diemunsch P, Moussallieh FM, Namer IJ, Charles AL, Lindner V, Agnus V, Geny B, Marescaux J (2015) Metabolism-guided bowel resection: potential role and accuracy of instant capillary lactates to identify the optimal resection site. Surg Innov 22:453-61. | LEAK OXPHOS | N S CIV | Pig | Endothelial;epithelial;mesothelial cell | |
Haegler 2015 Toxicology | 2015 | Haegler P, Grünig D, Berger B, Krähenbühl S, Bouitbir J (2015) Impaired mitochondrial function in HepG2 cells treated with hydroxy-cobalamin[c-lactam]: A cell model for idiosyncratic toxicity. Toxicology 336:48-58. | OXPHOS | N S CIV NS | Human | Liver Other cell lines | |
Lehtola 2015 Master's Thesis | 2015 | Lehtola A (2015) Main protein component of high density lipoprotein, apolipoprotein A1, modulates leukocyte cell respiration. Master's Thesis 1-44. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Intact cells Permeabilized cells | Human | Blood cells Other cell lines Lymphocyte |