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	Year	Reference	Coupling	Pathway	Preparation	Organism	Tissue;cell
Fisar 2016a Folia Biol (Praha)	2016	Fisar Z, Hroudova J (2016) Pig brain mitochondria as a biological model for study of mitochondrial respiration. Folia Biol (Praha) 62:15-25.	LEAK OXPHOS ET	N S NS ROX	Isolated mitochondria	Pig	Nervous system
Wijermars 2016 Kidney Int	2016	Wijermars LG, Schaapherder AF, de Vries DK, Verschuren L, Wuest RC, Kostidis S, Mayboroda OA, Prins F, Ringers J, Bierau J, Bakker JA, Kooistra T, Lindeman JH (2016) Defective postreperfusion metabolic recovery directly associates with incident delayed graft function. Kidney Int 90:181-91.	OXPHOS	N S NS ROX	Permeabilized tissue	Human	Kidney
Raesaenen 2016 Proc Natl Acad Sci U S A	2016	Räsänen M, Degerman J, Nissinen TA, Miinalainen I, Kerkelä R, Siltanen A, Backman JT, Mervaala E, Hulmi JJ, Kivelä R, Alitalo K (2016) VEGF-B gene therapy inhibits doxorubicin-induced cardiotoxicity by endothelial protection. Proc Natl Acad Sci U S A 113:13144-49.	LEAK OXPHOS ET	N S NS	Homogenate	Mouse	Heart
Asseburg 2016 Neuromolecular Med	2016	Asseburg H, Schäfer C, Müller M, Hagl S, Pohland M, Berressem D, Borchiellini M, Plank C, Eckert GP (2016) Effects of grape skin extract on age-related mitochondrial dysfunction, memory and life span in C57BL/6J mice. Neuromolecular Med 18:378-95.	LEAK OXPHOS ET	N S CIV NS ROX	Isolated mitochondria	Mouse	Nervous system
Johnson 2016 Diabetes	2016	Johnson ML, Distelmaier K, Lanza IR, Irving BA, Robinson MM, Konopka AR, Shulman GI, Nair KS (2016) Mechanism by which caloric restriction improves insulin sensitivity in sedentary obese adults. Diabetes 65:74-84.	LEAK OXPHOS ET	N S NS ROX	Isolated mitochondria	Human	Skeletal muscle
Ryan 2016 J Mol Cell Cardiol	2016	Ryan TE, Schmidt CA, Alleman RJ, Tsang AM, Green TD, Neufer PD, Brown DA, McClung JM (2016) Mitochondrial therapy improves limb perfusion and myopathy following hindlimb ischemia. J Mol Cell Cardiol 97:191-6.	LEAK OXPHOS ET	N S CIV NS ROX	Isolated mitochondria	Mouse	Skeletal muscle
Mezera 2016 Oxid Med Cell Longev	2016	Mezera V, Endlicher R, Kucera O, Sobotka O, Drahota Z, Cervinkova Z (2016) Effects of epigallocatechin gallate on tert-butyl hydroperoxide-induced mitochondrial dysfunction in rat liver mitochondria and hepatocytes. Oxid Med Cell Longev 7573131:8pp.	LEAK OXPHOS	N S	Permeabilized cells Isolated mitochondria	Rat	Liver
Ehinger 2016 Mov Disord	2016	Ehinger JK, Morota S, Hansson MJ, Gesine P, Elmér E (2016) Mitochondrial respiratory function in peripheral blood cells from Huntington’s disease patients. Mov Disord doi:10.1002/mdc3.12308.	LEAK ROUTINE OXPHOS ET	N S CIV NS Other combinations ROX	Permeabilized cells Intact cells	Human	Blood cells Lymphocyte Platelet
Queliconi 2016 PLOS ONE	2016	Queliconi BB, Kowaltowski AJ, Gottlieb RA (2016) Bicarbonate increases ischemia-reperfusion damage by inhibiting mitophagy. PLOS ONE 11:e0167678.	LEAK OXPHOS ET	S ROX	Isolated mitochondria	Rat	Heart
Salin 2016 J Exp Biol	2016	Salin K, Auer SK, Anderson GJ, Selman C, Metcalfe NB (2016) Inadequate food intake at high temperatures is related to depressed mitochondrial respiratory capacity. J Exp Biol 219:1356-62.	LEAK OXPHOS	N S CIV NS Other combinations ROX	Permeabilized tissue	Fishes	Skeletal muscle Liver
Morad 2016 J Lipid Res	2016	Morad SA, Ryan TE, Neufer PD, Zeczycki TN, Davis TS, MacDougall MR, Fox TE, Tan SF, Feith DJ, Loughran TP Jr, Kester M, Claxton DF, Barth BM, Deering TG, Cabot MC (2016) Ceramide-tamoxifen regimen targets bioenergetic elements in acute myelogenous leukemia. J Lipid Res 57:1231-42.	LEAK OXPHOS	N S NS	Permeabilized cells	Human	Blood cells Other cell lines
Mills 2016 Cell	2016	Mills EL, Kelly B, Logan A, Costa ASH, Varma M, Bryant CE, Tourlomousis P, Däbritz JHM, Gottlieb E, Latorre I, Corr SC, McManus G, Ryan D, Jacobs HT, Szibor M, Xavier RJ, Braun T, Frezza C, Murphy MP, O’Neill LA (2016) Succinate dehydrogen2016ase supports metabolic repurposing of mitochondria to drive inflammatory macrophages. Cell 167:457-70.e13. https://doi.org/10.1016/j.cell.2016.08.064.		S			Macrophage-derived
Amigo 2016 Aging Cell	2016	Amigo I, Menezes-Filho SL, Luévano-Martínez LA, Chausse B, Kowaltowski AJ (2016) Caloric restriction increases brain mitochondrial calcium retention capacity and protects against excitotoxicity. Aging Cell 16:73-81.	LEAK OXPHOS ET	N S	Isolated mitochondria	Mouse	Nervous system
Rohlenova 2016 Antioxid Redox Signal	2016	Rohlenova K, Sachaphibulkij K, Stursa J, Bezawork-Geleta A, Blecha J, Endaya B, Werner L, Cerny J, Zobalova R, Goodwin J, Spacek T, Alisadeh E, Yan B, Nguyen M, Vondrusova M, Sobol M, Jezek P, Hozak P, Truksa J, Rohlena J, Dong L, Neuzil J (2016) Selective disruption of respiratory supercomplexes as a new strategy to suppress Her2^high breast cancer. Antioxid Redox Signal 26:84-103.	LEAK ROUTINE ET	N S Other combinations	Permeabilized cells Homogenate	Human Mouse	Liver Genital Other cell lines
Van Schaardenburgh 2016 PLOS ONE	2016	van Schaardenburgh M, Wohlwend M, Rognmo Ø, Mattsson EJ (2016) Mitochondrial respiration after one session of calf raise exercise in patients with peripheral vascular disease and healthy older adults. PLOS ONE 11:e0165038.	LEAK OXPHOS ET	F N S NS	Permeabilized tissue	Human	Skeletal muscle
Singh 2016 Mol Neurobiol	2016	Singh N, Hroudová J, Fišar Z (2016) In vitro effects of cognitives and nootropics on mitochondrial respiration and monoamine oxidase activity. Mol Neurobiol 54:5894-904.	LEAK	N S ROX	Isolated mitochondria	Pig	Nervous system
Hagl 2016 Nutr Neurosci	2016	Hagl S, Berressem D, Grewal R, Grebenstein N, Frank J, Eckert GP (2016) Rice bran extract improves mitochondrial dysfunction in brains of aged NMRI mice. Nutr Neurosci 19:1-10.	LEAK OXPHOS ET	N S CIV NS ROX	Isolated mitochondria	Mouse	Nervous system
Koncsos 2016 Am J Physiol Heart Circ Physiol	2016	Koncsos G, Varga ZV, Baranyai T, Boengler K, Rohrbach S, Li L, Schlüter KD, Schreckenberg R, Radovits T, Oláh A, Mátyás C, Lux Á, Al-Khrasani M, Komlódi T, Bukosza N, Máthé D, Deres L, Barteková M, Rajtík T, Adameová A, Szigeti K, Hamar P, Helyes Z, Tretter L, Pacher P, Merkely B, Giricz Z, Schulz R, Ferdinandy P (2016) Diastolic dysfunction in prediabetic male rats: role of mitochondrial oxidative stress. Am J Physiol Heart Circ Physiol 311:H927-43.	OXPHOS	N S NS	Isolated mitochondria	Rat	Heart
Price 2016 J Thermal Biol	2016	Price ER, Sirsat TS, Sirsat SKG, Kang G, Keereetaweep J, Aziz M, Chapman KD, Dzialowski EM (2016) Thermal acclimation in American alligators: Effects of temperature regime on growth rate, mitochondrial function, and membrane composition. J Thermal Biol p11.	LEAK OXPHOS ET	N S CIV NS ROX	Permeabilized tissue	Reptiles	Heart Skeletal muscle
Casinelli 2016 Cell Death Discov	2016	Casinelli G, LaRosa J, Sharma M, Cherok E, Banerjee S, Branca M, Edmunds L, Wang Y, Sims-Lucas S, Churley L, Kelly S, Sun M, Stolz D, Graves JA (2016) N-Myc overexpression increases cisplatin resistance in neuroblastoma via deregulation of mitochondrial dynamics. Cell Death Discov 2:16082.	OXPHOS LEAK	N S	Permeabilized cells	Human	Nervous system Other cell lines
Tam 2016 Eur J Appl Physiol	2016	Tam E, Bruseghini P, Calabria E, Sacco LD, Doria C, Grassi B, Pietrangelo T, Pogliaghi S, Reggiani C, Salvadego D, Schena F, Toniolo L, Verratti V, Vernillo G, Capelli C (2016) Gokyo Khumbu/Ama Dablam Trek 2012: effects of physical training and high-altitude exposure on oxidative metabolism, muscle composition, and metabolic cost of walking in women. Eur J Appl Physiol 116:129-44.	LEAK OXPHOS	N S NS ROX	Permeabilized tissue	Human	Skeletal muscle
Gorbacheva 2016 International Symposium Mitochondrial Motility	2016	Gorbacheva OS, Strutynskyi RB, Khmil NV, Belosludtseva NV, Murzaeva SV, Korobeynikova MO, Alilova GA, Lezhnev EI, Mironova GD (2016) Study of the influence of flocalin on the energy and ion exchanges in rat liver mitochondria. International Symposium Mitochondrial Motility 73-7.	LEAK	F N S		Rat	Liver
Hartmannova 2016 Hum Mol Genet	2016	Hartmannová H, Piherová L, Tauchmannová K, Kidd K, Acott PD, Crocker JF, Oussedik Y, Mallet M, Hodaňová K, Stránecký V, Přistoupilová A, Barešová V, Jedličková I, Živná M, Sovová J, Hůlková H, Robins V, Vrbacký M, Pecina P, Kaplanová V, Houštěk J, Mráček T, Thibeault Y, Bleyer AJ, Kmoch S (2016) Acadian variant of Fanconi syndrome is caused by mitochondrial respiratory chain complex I deficiency due to a non-coding mutation in complex I assembly factor NDUFAF6. Hum Mol Genet 25:4062-79.	LEAK OXPHOS ET	N S Gp CIV NS ROX	Permeabilized cells	Human	Fibroblast
Granata 2016 FASEB J	2016	Granata C, Oliveira RS, Little JP, Renner K, Bishop DJ (2016) Mitochondrial adaptations to high-volume exercise training are rapidly reversed after a reduction in training volume in human skeletal muscle. FASEB J 30:3413-23. https://doi.org/10.1096/fj.201500100R	LEAK OXPHOS ET	N S CIV NS ROX	Permeabilized tissue	Human	Skeletal muscle
Cecatto 2016 Thesis	2016	Cecatto C (2016) Efeitos de acidos graxos hidroxilados de cadeia longa acumulados nas deficiencias da 3-hidroxiacil CoA desidrogenase de cadeia longa e da proteina trifunctional mitocondrial sobre a homeostase energetica mitochondrial nos musculos cardiaco e esqueletico de ratos jovens. Dissertation p103.	LEAK OXPHOS ET	N S	Permeabilized tissue Isolated mitochondria	Rat	Heart Skeletal muscle
Pamenter 2016 Biol Lett	2016	Pamenter ME, Gomez CR, Richards JG, Milsom WK (2016) Mitochondrial responses to prolonged anoxia in brain of red-eared slider turtles. Biol Lett 12. pii: 20150797.	LEAK OXPHOS ET	N S CIV ROX	Permeabilized tissue	Reptiles	Nervous system
Gregg 2016 Diabetes	2016	Gregg T, Poudel C, Schmidt BA, Dhillon RS, Sdao SM, Truchan NA, Baar EL, Fernandez LA, Denu JM, Eliceiri KW, Rogers JD, Kimple ME, Lamming DW, Merrins MJ (2016) Pancreatic β cells from mice offset age-associated mitochondrial deficiency with reduced K_ATP channel activity. Diabetes 65:2700-10.	LEAK OXPHOS ET	N S NS ROX	Permeabilized tissue	Human Mouse	Islet cell;pancreas;thymus Other cell lines
Timpani 2016 Neurotherapeutics	2016	Timpani CA, Trewin AJ, Stojanovska V, Robinson A, Goodman CA, Nurgali K, Betik AC, Stepto N, Hayes A, McConell GK, Rybalka E (2016) Attempting to compensate for reduced neuronal nitric oxide synthase protein with nitrate supplementation cannot overcome metabolic dysfunction but rather has detrimental effects in Dystrophin-deficient mdx muscle. Neurotherapeutics 14:429-46.	LEAK OXPHOS ET	N CIV NS Other combinations ROX S	Permeabilized tissue	Mouse	Skeletal muscle
Lim 2016 FASEB J	2016	Lim SC, Hroudová J, Van Bergen NJ, Lopez Sanchez MI, Trounce IA, McKenzie M (2016) Loss of mitochondrial DNA-encoded protein ND1 results in disruption of complex I biogenesis during early stages of assembly. FASEB J 30:2236-48.	OXPHOS ET	N S NS ROX	Permeabilized cells	Human	Other cell lines
Hagl 2016 Neuromolecular Med	2016	Hagl S, Asseburg H, Heinrich M, Sus N, Blumrich EM, Dringen R, Frank J, Eckert GP (2016) Effects of long-term rice bran extract supplementation on survival, cognition and brain mitochondrial function in aged NMRI mice. Neuromolecular Med 18:347-63.	LEAK OXPHOS ET	N S CIV NS ROX	Isolated mitochondria	Mouse	Nervous system
Shrum 2016 J Kidney	2016	Shrum S, MacMillan-Crow LA, Parajuli N (2016) Cold storage exacerbates renal and mitochondrial dysfunction following transplantation. J Kidney 2 pii: 114.	OXPHOS	N S CIV	Permeabilized tissue	Rat	Kidney
Karlsson 2016 Shock	2016	Karlsson M, Hara N, Morata S, Sjövall F, Kilbaugh T, Hansson MJ, Uchino H, Elmér E (2016) Diverse and tissue-specific mitochondrial respiratory response in a mouse model of sepsis-induced multiple organ failure. Shock 45:404-10.	LEAK OXPHOS ET	N S CIV NS	Homogenate	Mouse	Nervous system Liver
Fisar 2016b Folia Biol (Praha)	2016	Fisar Z, Hroudova J, Singh N, Koprivova A, Maceckova D (2016) Effect of simvastatin, coenzyme Q10, resveratrol, acetylcysteine and acetylcarnitine on mitochondrial respiration. Folia Biol (Praha) 62:53-66.	OXPHOS ET	N S CIV NS ROX	Isolated mitochondria	Pig	Nervous system
Uecal 2016 J Neurotrauma	2016	Üçal M, Kraitsy K, Weidinger A, Paier-Pourani J, Patz S, Fink B, Molcanyi M, Schäfer U (2016) Comprehensive profiling of modulation of nitric oxide levels and mitochondrial activity in the injured brain: an experimental study based on the fluid percussion injury model in rats. J Neurotrauma 34:475-86.	LEAK OXPHOS	N S	Homogenate	Rat	Nervous system
Pohland 2016 Neurochem Res	2016	Pohland M, Hagl S, Pellowska M, Wurglics M, Schubert-Zsilavecz M, Eckert GP (2016) MH84: a novel γ-secretase modulator/PPARγ agonist-improves mitochondrial dysfunction in a cellular model of Alzheimer's disease. Neurochem Res 41:231-42.	LEAK OXPHOS ET	N S CIV NS ROX	Permeabilized cells	Human	Kidney HEK
Krischek 2016 Mol Reprod Dev	2016	Krischek C, Janisch S, Naraballobh W, Brunner R, Wimmers K, Wicke M (2016) Altered incubation temperatures between embryonic Days 7 and 13 influence the weights and the mitochondrial respiratory and enzyme activities in breast and leg muscles of broiler embryos. Mol Reprod Dev 83:71-8.	LEAK OXPHOS	N S	Permeabilized tissue	Chicken	Skeletal muscle
Stepanova 2016 Biochim Biophys Acta	2016	Stepanova A, Shurubor Y, Valsecchi F, Manfredi G, Galkin A (2016) Differential susceptibility of mitochondrial complex II to inhibition by oxaloacetate in brain and heart. Biochim Biophys Acta 1857:1561-8.		S	Oxidase;biochemical oxidation	Mouse	Heart Nervous system
Frey 2016 Biochim Biophys Acta	2016	Frey S, Geffroy G, Desquiret-Dumas V, Gueguen N, Bris C, Belal S, Amati-Bonneau P, Chevrollier A, Barth M, Henrion D, Lenaers G, Bonneau D, Reynier P, Procaccio V (2016) The addition of ketone bodies alleviates mitochondrial dysfunction by restoring complex I assembly in a MELAS cellular model. Biochim Biophys Acta 1863:284-91.	ROUTINE LEAK ET	N S NS	Permeabilized cells Intact cells	Human	Nervous system
Du 2016 J Exp Biol	2016	Du SN, Mahalingam S, Borowiec BG, Scott GR (2016) Mitochondrial physiology and reactive oxygen species production are altered by hypoxia acclimation in killifish (Fundulus heteroclitus). J Exp Biol 219:1130-8.	LEAK OXPHOS ET	N S CIV NS	Isolated mitochondria	Fishes	Liver
Dias 2016 Neurobiol Aging	2016	Dias C, Lourenço CF, Ferreiro E, Barbosa RM, Laranjinha J, Ledo A (2016) Age-dependent changes in the glutamate-nitric oxide pathway in the hippocampus of the triple transgenic model of Alzheimer's disease: implications for neurometabolic regulation. Neurobiol Aging 46:84-95.	LEAK ET	N S ROX	Permeabilized tissue	Mouse	Nervous system
Zabielski 2016 Diabetes	2016	Zabielski P, Lanza IR, Gopala S, Holtz Heppelmann CJ, Bergen HR 3rd, Dasari S, Nair KS (2016) Altered skeletal muscle mitochondrial proteome as the basis of disruption of mitochondrial function in diabetic mice. Diabetes 65:561-73.	LEAK OXPHOS ET	F N S NS ROX	Permeabilized cells	Mouse	Skeletal muscle
Vevera 2016 Physiol Res	2016	Vevera J, Fišar Z, Nekovářová T, Vrablík M, Zlatohlávek L, Hroudová J, Singh N, Raboch J, Valeš K (2016) Statin-induced changes in mitochondrial respiration in blood platelets in rats and human with dyslipidemia. Physiol Res 65:777-88.	LEAK ROUTINE OXPHOS ET	N S NS Other combinations ROX	Intact cells Permeabilized cells	Human Rat	Blood cells Platelet
Munro 2016 Free Radic Biol Med	2016	Munro D, Banh S, Sotiri E, Tamanna N, Treberg JR (2016) The thioredoxin and glutathione-dependent H₂O₂ consumption pathways in muscle mitochondria: Involvement in H₂O₂ metabolism and consequence to H₂O₂ efflux assays. Free Radic Biol Med 96:334-46.	LEAK OXPHOS	N S	Isolated mitochondria	Rat	Skeletal muscle
Fink 2016 Am J Physiol Regul Integr Comp Physiol	2016	Fink BD, Bai F, Yu L, Sivitz WI (2016) Impaired utilization of membrane potential by complex II-energized mitochondria of obese, diabetic mice assessed using ADP recycling methodology. Am J Physiol Regul Integr Comp Physiol 311:756-63.	OXPHOS LEAK	S	Isolated mitochondria	Mouse	Skeletal muscle
Duteil 2016 Cell Rep	2016	Duteil D, Tosic M, Lausecker F, Nenseth HZ, Müller JM, Urban S, Willmann D, Petroll K, Messaddeq N, Arrigoni L, Manke T, Kornfeld JW, Brüning JC, Zagoriy V, Meret M, Dengjel J, Kanouni T, Schüle R (2016) Lsd1 ablation triggers metabolic reprogramming of brown adipose tissue. Cell Rep 17:1008-21.	ET	F N S NS	Permeabilized tissue	Mouse	Fat
Valek 2016 Redox Biol	2016	Valek L, Häussler A, Dröse S, Eaton P, Schröder K, Tegeder I (2016) Redox-guided axonal regrowth requires cyclic GMP dependent protein kinase 1: Implication for neuropathic pain. Redox Biol 11:176-91.	OXPHOS LEAK	N S CIV ROX	Homogenate	Mouse	Nervous system
Berressem 2016 PLOS ONE	2016	Berressem D, Koch K, Franke N, Klein J, Eckert GP (2016) Intravenous treatment with a long-chain omega-3 lipid emulsion provides neuroprotection in a murine model of ischemic stroke - a pilot study. PLOS ONE 11:e0167329.	LEAK OXPHOS ET	N S CIV NS ROX	Isolated mitochondria	Mouse	Nervous system
Maarman 2016 J Appl Physiol (1985)	2016	Maarman GJ, Andrew BM, Blackhurst DM, Ojuka EO (2016) Melatonin protects against uric acid-induced mitochondrial dysfunction, oxidative stress, and triglyceride accumulation in C₂C₁₂ myotubes. J Appl Physiol (1985) 122:1003-10.	LEAK ROUTINE OXPHOS ET	N S CIV NS ROX	Permeabilized cells Intact cells	Mouse	Skeletal muscle
King 2016 Redox Biol	2016	King AL, Mantena SK, Andringa KK, Millender-Swain T, Dunham-Snary KJ, Oliva CR, Griguer CE, Bailey SM (2016) The methyl donor S-adenosylmethionine prevents liver hypoxia and dysregulation of mitochondrial bioenergetic function in a rat model of alcohol-induced fatty liver disease. Redox Biol 9:188-97.	OXPHOS	S	Isolated mitochondria	Rat	Liver
Sheremet 2016 Biochemistry (Moscow)	2016	Sheremet NL, Nevinitsyna TA, Zhorzholadze NV, Ronzina IA, Itkis YS, Krylova TD, Tsygankova PG, Malakhova VA, Zakharova EY, Tokarchuk AV, Panteleeva AA, Karger EM, Lyamzaev KG, Avetisov SE (2016) Previously unclassified mutation of mtDNA m.3472T>C: evidence of pathogenicity in Leber’s hereditary optic neuropathy. Biochemistry (Moscow) BM16-078.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Permeabilized cells Intact cells	Human	Endothelial;epithelial;mesothelial cell Fibroblast Platelet
Richman 2016 Nat Commun	2016	Richman TR, Spåhr H, Ermer JA, Davies SM, Viola HM, Bates KA, Papadimitriou J, Hool LC, Rodger J, Larsson NG, Rackham O, Filipovska A (2016) Loss of the RNA-binding protein TACO1 causes late-onset mitochondrial dysfunction in mice. Nat Commun 7:11884.	LEAK OXPHOS	N S CIV	Isolated mitochondria	Mouse	Heart Liver
Diana 2016 Surg Endosc	2016	Diana M, Noll E, Charles AL, Diemunsch P, Geny B, Liu YY, Marchegiani F, Schiraldi L, Agnus V, Lindner V, Swanström L, Dallemagne B, Marescaux J (2016) Precision real-time evaluation of bowel perfusion: accuracy of confocal endomicroscopy assessment of stoma in a controlled hemorrhagic shock model. Surg Endosc 31:680-91.	OXPHOS LEAK	S	Permeabilized tissue	Pig	Endothelial;epithelial;mesothelial cell
Nemeth 2016 FASEB J	2016	Németh B, Doczi J, Csete D, Kacso G, Ravasz D, Adams D, Kiss G, Nagy AM, Horvath G, Tretter L, Mócsai A, Csépányi-Kömi R, Iordanov I, Adam-Vizi V, Chinopoulos C (2016) Abolition of mitochondrial substrate-level phosphorylation by itaconic acid produced by LPS-induced Irg1 expression in cells of murine macrophage lineage. FASEB J 30:286-300.	LEAK OXPHOS	S	Isolated mitochondria	Mouse	Liver
Schoepf 2016 FEBS J	2016	Schöpf B, Schäfer G, Weber A, Talasz H, Eder IE, Klocker H, Gnaiger E (2016) Oxidative phosphorylation and mitochondrial function differ between human prostate tissue and cultured cells. https://doi.org/10.1111/febs.13733	LEAK OXPHOS ET	F N S NS Other combinations ROX	Permeabilized cells Permeabilized tissue	Human	Endothelial;epithelial;mesothelial cell Genital Other cell lines Fibroblast
Reich 2016 Thesis	2016	Reich V (2016) Pathophysiologie und Verfahrensentwicklung: Mechanismen der Metabolisierung von Schwefelwasserstoff im mitochondrialen Atmungskreislauf von Lungenalveolarmakrophagen. Dissertation p91.	LEAK OXPHOS ET	N S CIV NS ROX	Intact cells Permeabilized cells	Mouse	Macrophage-derived
Lund 2016 J Physiol	2016	Lund MT, Kristensen M, Hansen M, Tveskov L, Floyd AK, Støckel M, Vainer B, Poulsen SS, Helge JW, Prats C, Dela F (2016) Hepatic mitochondrial oxidative phosphorylation is normal in obese patients with and without type 2 diabetes. J Physiol 594:4351-8.	LEAK OXPHOS ET	F N S CIV NS ROX	Permeabilized tissue	Human	Liver
De Carvalho 2016 J Cell Biochem	2016	de Carvalho AK, da Silva S, Serafini E, de Souza DR, Farias HR, de Bem Silveira G, Silveira PC, de Souza CT, Portela LV, Muller AP (2016) Prior exercise training prevent hyperglycemia in STZ mice by increasing hepatic glycogen and mitochondrial function on skeletal muscle. J Cell Biochem 118:678-85.	LEAK OXPHOS	S	Homogenate	Mouse	Skeletal muscle Liver
Fisar 2016 Curr Alzheimer Res	2016	Fišar Z, Hroudová J, Hansíková H, Spáčilová J, Lelková P, Wenchich L, Jirák R, Zvěřová M, Zeman J, Martásek P, Raboch J (2016) Mitochondrial respiration in the platelets of patients with Alzheimer's disease. Curr Alzheimer Res 13:930-41.	LEAK OXPHOS ET	N S NS ROX	Intact cells Permeabilized cells	Human	Blood cells Platelet
Takahashi 2016 Exp Gerontol	2016	Takahashi K, Ohsawa I, Shirasawa T, Takahashi M (2016) Early-onset motor impairment and increased accumulation of phosphorylated α-synuclein in the motor cortex of normal aging mice are ameliorated by coenzyme Q. Exp Gerontol 81:65-75.	OXPHOS	N S ROX	Isolated mitochondria	Mouse	Nervous system
Silva Ramos 2016 Biochim Biophys Acta	2016	Silva Ramos E, Larsson NG, Mourier A (2016) Bioenergetic roles of mitochondrial fusion. Biochim Biophys Acta 1857:1277-83.	LEAK OXPHOS ET	S Gp	Permeabilized cells	Mouse	Fibroblast
Morton 2016 Nat Med	2016	Morton NM, Beltram J, Carter RN, Michailidou Z, Gorjanc G, McFadden C, Barrios-Llerena ME, Rodriguez-Cuenca S, Gibbins MT, Aird RE, Moreno-Navarrete JM, Munger SC, Svenson KL, Gastaldello A, Ramage L, Naredo G, Zeyda M, Wang ZV, Howie AF, Saari A, Sipilä P, Stulnig TM, Gudnason V, Kenyon CJ, Seckl JR, Walker BR, Webster SP, Dunbar DR, Churchill GA, Vidal-Puig A, Fernandez-Real JM, Emilsson V, Horvat S (2016) Genetic identification of thiosulfate sulfurtransferase as an adipocyte-expressed antidiabetic target in mice selected for leanness. Nat Med 22:771-9.	LEAK OXPHOS	N S	Isolated mitochondria	Mouse	Liver
Hamilton 2016 Am J Physiol Heart Circ Physiol	2016	Hamilton DJ, Zhang A, Li S, Cao TN, Smith JA, Vedula I, Cordero-Reyes AM, Youker KA, Torre-Amione G, Gupte AA (2016) Combination of angiotensin II and l-NG-nitroarginine methyl ester exacerbates mitochondrial dysfunction and oxidative stress to cause heart failure. Am J Physiol Heart Circ Physiol 310:H667-80.	LEAK OXPHOS	F N S NS Other combinations ROX	Permeabilized tissue Isolated mitochondria	Mouse	Heart
Barth 2016 Thesis	2016	Barth C (2016) Effekte einer intermittierenden Hyperoxie auf die mitochondriale Atmung in Alveolarmakrophagen. Dissertation p69.	LEAK ROUTINE OXPHOS	N S CIV NS ROX	Permeabilized cells Intact cells	Mouse	Lung;gill Macrophage-derived
Moon 2016 J Biol Chem	2016	Moon SH, Mancuso DJ, Sims HF, Liu X, Nguyen AL, Yang K, Guan S, Dilthey BG, Jenkins CM, Weinheimer CJ, Kovacs A, Abendschein D, Gross RW (2016) Cardiac myocyte-specific knock-out of calcium-independent phospholipase A2γ (iPLA2γ) decreases oxidized fatty acids during ischemia/reperfusion and reduces infarct size. J Biol Chem 291:19687-700.	LEAK OXPHOS	F N S NS Other combinations ROX	Isolated mitochondria	Mouse	Heart
Bai 2016 PLOS ONE	2016	Bai F, Fink BD, Yu L, Sivitz WI (2016) Voltage-dependent regulation of Complex II energized mitochondrial oxygen flux. PLOS ONE 11:e0154982.	LEAK OXPHOS ET	N S CIV NS	Isolated mitochondria	Mouse	Heart Skeletal muscle Nervous system Liver
Du 2016 Thesis	2016	Du X (2016) Anthropogenic pollution effects on mitochondrial energy metabolism, gene expression, and genotypes of natural Fundulus heteroclitus populations. Dissertation p175.	LEAK OXPHOS ET	S CIV ROX N NS	Permeabilized cells	Fishes	Liver
Wuest 2016 Cardiovasc Res	2016	Wüst RC, de Vries HJ, Wintjes LT, Rodenburg RJ, Niessen HW, Stienen GJ (2016) Mitochondrial complex I dysfunction and altered NAD(P)H kinetics in rat myocardium in cardiac right ventricular hypertrophy and failure. Cardiovasc Res 111:362-72.	LEAK OXPHOS	N S	Intact cells Permeabilized tissue	Rat	Heart
Brecht 2016 Toxicol In Vitro	2016	Brecht K, Riebel V, Couttet P, Paech F, Wolf A, Chibout SD, Pognan F, Krähenbühl S, Uteng M (2016) Mechanistic insights into selective killing of OXPHOS-dependent cancer cells by arctigenin. Toxicol In Vitro 40:55-65.	LEAK OXPHOS ET	N S CIV Other combinations ROX DQ	Permeabilized cells	Human	Islet cell;pancreas;thymus
Amaral 2016 J Neurochem	2016	Amaral AU, Cecatto C, Castilho RF, Wajner M (2016) 2-methylcitric acid impairs glutamate metabolism and induces permeability transition in brain mitochondria. J Neurochem 137:62-75.	LEAK OXPHOS ET	N S NS	Isolated mitochondria	Rat	Nervous system
Edgett 2016 Exp Physiol	2016	Edgett BA, Hughes MC, Matusiak JB, Perry CG, Simpson CA, Gurd BJ (2016) SIRT3 gene expression but not SIRT3 subcellular localization is altered in response to fasting and exercise in human skeletal muscle. Exp Physiol 101:1101-13.	OXPHOS	F N S NS	Permeabilized tissue	Human	Skeletal muscle
Roy 2016 Free Radic Biol Med	2016	Roy J, Fauconnier J, Oger C, Farah C, Angebault-Prouteau C, Thireau J, Bideaux P, Scheuermann V, Bultel-Poncé V, Demion M, Galano JM, Durand T, Lee JC, Le Guennec JY (2016) Non-enzymatic oxidized metabolite of DHA, 4(RS)-4-F_4t-neuroprostane protects the heart against reperfusion injury. Free Radic Biol Med 102:229-39.	OXPHOS ET	N S NS	Permeabilized cells	Rat	Heart
Hawley 2016 Diabetes	2016	Hawley SA, Ford RJ, Smith BK, Gowans GJ, Mancini SJ, Pitt RD, Day EA, Salt IP, Steinberg GR, Hardie DG (2016) The Na+/glucose cotransporter inhibitor canagliflozin activates AMPK by inhibiting mitochondrial function and increasing cellular AMP levels. Diabetes 65:2784-94.	OXPHOS	N S	Permeabilized cells	Human Mouse	Liver HEK
Galli 2016 Am J Physiol Regul Integr Comp Physiol	2016	Galli GL, Crossley J, Elsey RM, Dzialowski EM, Shiels HA, Crossley DA 2nd (2016) Developmental plasticity of mitochondrial function in American alligators, Alligator mississippiensis. Am J Physiol Regul Integr Comp Physiol 311:R1164-72.	LEAK OXPHOS ET	N S CIV Other combinations ROX	Isolated mitochondria	Reptiles	Heart
Cacabelos 2016 Acta Neuropathol Commun	2016	Cacabelos D, Ramírez-Núñez O, Granado-Serrano AB, Torres P, Ayala V, Moiseeva V, Povedano M, Ferrer I, Pamplona R, Portero-Otin M, Boada J (2016) Early and gender-specific differences in spinal cord mitochondrial function and oxidative stress markers in a mouse model of ALS. Acta Neuropathol Commun 4:3.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Permeabilized tissue Intact cells	Mouse	Nervous system Other cell lines
Reis 2016 Aging (Albany NY)	2016	Reis FC, Branquinho JL, Brandão BB, Guerra BA, Silva ID, Frontini A, Thomou T, Sartini L, Cinti S, Kahn CR, Festuccia WT, Kowaltowski AJ, Mori MA (2016) Fat-specific Dicer deficiency accelerates aging and mitigates several effects of dietary restriction in mice. Aging (Albany NY) 8:1201-22.	LEAK	N S ROX	Permeabilized cells	Mouse	Fat
Tretter 2016 Biochim Biophys Acta	2016	Tretter L, Patocs A, Chinopoulos C (2016) Succinate, an intermediate in metabolism, signal transduction, ROS, hypoxia, and tumorigenesis. https://doi.org/10.1016/j.bbabio.2016.03.012	LEAK OXPHOS	N S NS
Lemieux 2016 Mitochondrion	2016	Lemieux H, Boemer F, van Galen G, Serteyn D, Amory H, Baise E, Cassart D, van Loon G, Marcillaud-Pitel C, Votion DM (2016) Mitochondrial function is altered in horse atypical myopathy. Mitochondrion 30:35-41.	OXPHOS ET	N S NS ROX	Permeabilized tissue	Horse	Skeletal muscle
Jacobs 2016 J Physiol	2016	Jacobs RA, Lundby AM, Fenk S, Gehrig S, Siebenmann C, Flück D, Kirk N, Hilty MP, Lundby C (2016) Twenty-eight days of exposure to 3,454 m increases mitochondrial volume density in human skeletal muscle. J Physiol 594:1151-66.	LEAK OXPHOS ET	F N S CIV NS ROX	Permeabilized tissue	Human	Skeletal muscle
Chu 2016 World J Gastroenterol	2016	Chu MJ, Premkumar R, Hickey AJ, Jiang Y, Delahunt B, Phillips AR, Bartlett A (2016) Steatotic livers are susceptible to normothermic ischemia-reperfusion injury from mitochondrial Complex-I dysfunction. World J Gastroenterol 22:4673-84.	LEAK OXPHOS ET	N S NS ROX	Homogenate	Rat	Liver
Santos 2016 Insect Biochem Mol Biol	2016	Santos DE, Alberici LC, Hartfelder K (2016) Mitochondrial structure and dynamics as critical factors in honey bee (Apis mellifera L.) caste development. Insect Biochem Mol Biol 73:1-11.	LEAK OXPHOS ET	S	Permeabilized tissue	Hexapods	Fat
Dechandt 2016 Anal Biochem	2016	Dechandt CRP, Couto-Lima CA, Alberici LC (2016) Triglyceride depletion of brown adipose tissue enables analysis of mitochondrial respiratory function in permeabilized biopsies. Anal Biochem 515:55-60.	LEAK OXPHOS ET	N S ROX	Permeabilized tissue	Rat	Fat
Tsai 2016 Sci Rep	2016	Tsai HH, Chang SC, Chou CH, Weng TP, Hsu CC, Wang JS (2016) Exercise training alleviates hypoxia-induced mitochondrial dysfunction in the lymphocytes of sedentary males. Sci Rep 6:35170.	LEAK ROUTINE OXPHOS ET	F N S NS Other combinations ROX	Permeabilized cells Intact cells	Human	Lymphocyte Blood cells
Bagur 2016 Biochim Biophys Acta	2016	Bagur R, Tanguy S, Foriel S, Grichine A, Sanchez C, Pernet-Gallay K, Kaambre T, Kuznetsov AV, Usson Y, Boucher F, Guzun R (2016) The impact of cardiac ischemia/reperfusion on the mitochondria-cytoskeleton interactions. Biochim Biophys Acta 1862:1159-71.	OXPHOS LEAK	N S	Permeabilized tissue	Rat	Heart
Li 2016 Neurochem Int	2016	Li H, Liu Y, Lin LT, Wang XR, Du SQ, Yan CQ, He T, Yang JW, Liu CZ (2016) Acupuncture reversed hippocampal mitochondrial dysfunction in vascular dementia rats. Neurochem Int 92:35-42.	LEAK OXPHOS	S	Isolated mitochondria	Rat	Nervous system
Franko 2016 Diabetes	2016	Franko A, Huypens P, Neschen S, Irmler M, Rozman J, Rathkolb B, Neff F, Prehn C, Dubois G, Baumann M, Massinger R, Gradinger D, Przemeck GK, Repp B, Aichler M, Feuchtinger A, Schommers P, Stöhr O, Sanchez-Lasheras C, Adamski J, Peter A, Prokisch H, Beckers J, Walch AK, Fuchs H, Wolf E, Schubert M, Wiesner RJ, Hrabě de Angelis M (2016) Bezafibrate improves insulin sensitivity and metabolic flexibility in STZ-treated diabetic mice. Diabetes 65:2540-52.	LEAK OXPHOS	N S CIV ROX	Permeabilized cells Permeabilized tissue	Human	Skeletal muscle Fibroblast
Torres 2016 Redox Biol	2016	Torres S, Matías N, Baulies A, Nuñez S, Alarcon-Vila C, Martinez L, Nuño N, Fernandez A, Caballeria J, Levade T, Gonzalez-Franquesa A, Garcia-Rovés P, Balboa E, Zanlungo S, Fabrías G, Casas J, Enrich C, Garcia-Ruiz C, Fernández-Checa JC (2016) Mitochondrial GSH replenishment as a potential therapeutic approach for Niemann Pick type C disease. Redox Biol 11:60-72.	LEAK ROUTINE OXPHOS ET	N S ROX	Homogenate Intact cells	Human Mouse	Nervous system Liver Endothelial;epithelial;mesothelial cell Fibroblast
Cannon 2016 Lung	2016	Cannon DT, Liu J, Sakurai R, Rossiter HB, Rehan VK (2016) Impaired lung mitochondrial respiration following perinatal nicotine exposure in rats. Lung 194:325-8.	LEAK OXPHOS ET	N S CIV NS	Permeabilized tissue	Rat	Lung;gill
Christensen 2016 J Appl Physiol (1985)	2016	Christensen PM, Jacobs RA, Bonne T, Flück D, Bangsbo J, Lundby C (2016) A short period of high-intensity interval training improves skeletal muscle mitochondrial function and pulmonary oxygen uptake kinetics. J Appl Physiol (1985) 120:1319-27.	LEAK OXPHOS ET	F N S CIV NS Other combinations ROX	Permeabilized tissue	Human	Skeletal muscle
LaBarge 2016 FASEB J	2016	LaBarge SA, Migdal CW, Buckner EH, Okuno H, Gertsman I, Stocks B, Barshop BA, Nalbandian SR, Philp A, McCurdy CE, Schenk S (2016) p300 is not required for skeletal muscle metabolic adaptation to endurance exercise training. FASEB J 30:1623-33.	LEAK OXPHOS ET	F N NS ROX S Other combinations	Permeabilized tissue	Mouse	Skeletal muscle
Chakraborty 2016 Pancreatology	2016	Chakraborty M, Hickey AJ, Petrov MS, Macdonald JR, Thompson N, Newby L, Sim D, Windsor JA, Phillips AR (2016) Mitochondrial dysfunction in peripheral blood mononuclear cells in early experimental and clinical acute pancreatitis. Pancreatology 16:739-47.	LEAK OXPHOS ROUTINE ET	N Gp CIV NS ROX S	Permeabilized cells	Human Rat	Blood cells
Mills 2016 Cell Metab	2016	Mills KF, Yoshida S, Stein LR, Uchida K, Yoshino J, Imai SI (2016) Long-term administration of nicotinamide mononucleotide mitigates age-associated physiological decline in mice. Cell Metab 24:1–12.	OXPHOS LEAK ET	N S NS	Permeabilized tissue	Mouse	Skeletal muscle
Assmann 2016 Cell Rep	2016	Assmann N, Dettmer K, Simbuerger JM, Broeker C, Nuernberger N, Renner K, Courtneidge H, Klootwijk ED, Duerkop A, Hall A, Kleta R, Oefner PJ, Reichold M, Reinders J (2016) Renal fanconi syndrome is caused by a mistargeting-based mitochondriopathy. Cell Rep 15:1423-9.	LEAK OXPHOS ET	F N S NS Other combinations ROX	Intact cells	Pig	Kidney Other cell lines
Ferguson 2016 J Bioenerg Biomembr	2016	Ferguson MA, Sutton RM, Karlsson M, Sjövall F, Becker LB, Berg RA, Margulies SS, Kilbaugh TJ (2016) Increased platelet mitochondrial respiration after cardiac arrest and resuscitation as a potential peripheral biosignature of cerebral bioenergetic dysfunction. J Bioenerg Biomembr 48:269-79.	LEAK ROUTINE OXPHOS ET	N S CIV NS ROX	Permeabilized cells Homogenate Intact cells	Pig	Nervous system Platelet
Gariani 2016 J Hepatol	2016	Gariani K, Ryu D, Menzies KJ, Yi HS, Stein S, Zhang H, Perino A, Lemos V, Katsyuba E, Jha P, Vijgen S, Rubbia-Brandt L, Kim YK, Kim JT, Kim KS, Shong M, Schoonjans K, Auwerx J (2016) Inhibiting poly ADP-ribosylation increases fatty acid oxidation and protects against fatty liver disease. J Hepatol 66:132-41.	OXPHOS	N S NS	Permeabilized tissue	Mouse	Liver
Jardim-Messeder 2016 Anticancer Res	2016	Jardim-Messeder D, Moreira-Pacheco F (2016) 3-Bromopyruvic acid inhibits tricarboxylic acid cycle and glutaminolysis in HepG2 cells. Anticancer Res 36:2233-41.	OXPHOS	CIV N S	Isolated mitochondria	Mouse	Liver Kidney
Wijermars 2016 Am J Transplant	2016	Wijermars LG, Schaapherder AF, Kostidis S, Wüst RC, Lindeman JH (2016) Succinate accumulation and ischemia reperfusion injury: of mice but not men - A study in renal ischemia reperfusion. Am J Transplant 16:2741-6.	LEAK OXPHOS ET	N S NS ROX	Permeabilized tissue	Human Pig Mouse Rat	Kidney
Stier 2016 Methods Ecol Evol	2016	Stier A, Romestaing C, Schull Q, Lefol E, Robin JP, Roussel D, Bize P (2016) How to measure mitochondrial function in birds using red blood cells: a case study in the king penguin and perspectives in ecology and evolution. Methods Ecol Evol doi:10.1111/2041-210X.12724.	LEAK ROUTINE OXPHOS ET	N S ROX	Permeabilized tissue Intact cells	Birds	Skeletal muscle Blood cells
Lores-Arnaiz 2016 Neurochem Res	2016	Lores-Arnaiz S, Lombardi P, Karadayian AG, Orgambide F, Cicerchia D, Bustamante J (2016) Brain cortex mitochondrial bioenergetics in synaptosomes and non-synaptic mitochondria during aging. Neurochem Res 41:353-63.	LEAK ROUTINE OXPHOS ET	N S	Isolated mitochondria Intact cells	Mouse	Nervous system
Sobotka 2016 J Bioenerg Biomembr	2016	Sobotka O, Endlicher R, Drahota Z, Kučera O, Rychtrmoc D, Raad M, Hakeem K, Červinková Z (2016) Impaired mitochondrial functions contribute to 3-bromopyruvate toxicity in primary rat and mouse hepatocytes. J Bioenerg Biomembr 48:363-73.	LEAK OXPHOS	N S CIV	Intact cells Permeabilized cells Homogenate Isolated mitochondria	Mouse Rat	Liver
Baris 2016 Am J Physiol Regul Integr Comp Physiol	2016	Baris TZ, Blier PU, Pichaud N, Crawford DL, Oleksiak MF (2016) Gene by environmental interactions affecting oxidative phosphorylation and thermal sensitivity. Am J Physiol Regul Integr Comp Physiol 311:R157-65.	LEAK OXPHOS ET	CIV NS ROX S	Permeabilized tissue	Fishes	Heart
Bonifacio 2016 Arch Toxicol	2016	Bonifacio A, Mullen PJ, Mityko IS, Navegantes LC, Bouitbir J, Krähenbühl S (2016) Simvastatin induces mitochondrial dysfunction and increased atrogin-1 expression in H9c2 cardiomyocytes and mice in vivo. Arch Toxicol 90:203-15. doi: 10.1007/s00204-014-1378-4	LEAK OXPHOS ET	N S DQ CIV NS	Permeabilized cells Permeabilized tissue Intact cells	Rat	Heart
Teulier 2016 Proc Biol Sci	2016	Teulier L, Weber JM, Crevier J, Darveau CA (2016) Proline as a fuel for insect flight: enhancing carbohydrate oxidation in hymenopterans. Proc Biol Sci 283: 20160333.	OXPHOS	F N S Gp NS Other combinations ROX	Permeabilized tissue	Hexapods	Skeletal muscle
Reynolds 2016 Am J Physiol Endocrinol Metab	2016	Reynolds MS, Hancock CR, Ray JD, Kener KB, Draney C, Garland K, Hardman J, Bikman BT, Tessem JS (2016) β-cell deletion of Nr4a1 and Nr4a3 nuclear receptors impedes mitochondrial respiration and insulin secretion. Am J Physiol Endocrinol Metab 311:E186-201.	LEAK ROUTINE OXPHOS ET	N S ROX	Permeabilized cells Intact cells	Rat	Islet cell;pancreas;thymus
Villani 2016 Mol Metab	2016	Villani LA, Smith BK, Marcinko K, Ford RJ, Broadfield LA, Green AE, Houde VP, Muti P, Tsakiridis T, Steinberg GR (2016) The diabetes medication Canagliflozin reduces cancer cell proliferation by inhibiting mitochondrial complex-I supported respiration. Mol Metab 5:1048-56.	OXPHOS	N S ROX	Permeabilized cells	Human	Genital
Kontro 2016 Thesis	2016	Kontro H (2016) Mitochondrial function and sirtuin expression in hippocampus of young and old high and low-capacity runner rats. Master's Thesis p35.	LEAK OXPHOS ET	N S NS ROX	Homogenate	Rat	Nervous system
Wang 2016 J Biol Chem	2016	Wang H, Lu J, Edmunds LR, Kulkarni S, Dolezal J, Tao J, Ranganathan S, Jackson L, Fromherz M, Stolz DB, Uppala R, Bharathi S, Monga SP, Goetzman ES, Prochownik EV (2016) Coordinated activities of multiple Myc-dependent and Myc-independent biosynthetic pathways in Hepatoblastoma. J Biol Chem 291:26241-51.	OXPHOS LEAK	N S NS	Homogenate	Mouse	Liver
Gomez 2016 Thesis	2016	Gomez CR (2016) Mitochondrial responses to anoxia exposure in red eared sliders (Trachemys scripta). Master's Thesis p102.	LEAK OXPHOS ET	S	Permeabilized cells Isolated mitochondria	Reptiles	Heart Nervous system
Witt 2016 Metab Brain Dis	2016	Witt AM, Larsen FS, Bjerring PN (2016) Accumulation of lactate in the rat brain during hyperammonaemia is not associated with impaired mitochondrial respiratory capacity. Metab Brain Dis 32:461-70.	LEAK OXPHOS ET	N S NS ROX	Homogenate	Rat	Nervous system
Liepinsh 2016 Biochem J	2016	Liepinsh E, Makrecka-Kuka M, Volska K, Kuka J, Makarova E, Antone U, Sevostjanovs E, Vilskersts R, Strods A, Tars K, Dambrova M (2016) Long-chain acylcarnitines determine ischaemia/reperfusion-induced damage in heart mitochondria. Biochem J 473:1191-202.	LEAK OXPHOS	S NS	Isolated mitochondria	Rat	Heart
MiPNet17.03 Shredder vs Fibers	2015-06-18	Mitochondrial respiration in permeabilized fibers versus homogenate from fish liver and heart. An application study with the PBI-Shredder.	LEAK OXPHOS ET	N S NS	Homogenate	Fishes	Heart Liver
Ramos-Filho 2015 PLoS One	2015	Ramos-Filho D, Chicaybam G, de-Souza-Ferreira E, Guerra Martinez C, Kurtenbach E, Casimiro-Lopes G, Galina A (2015) High intensity interval training (HIIT) induces specific changes in respiration and electron leakage in the mitochondria of different rat skeletal muscles. PLoS One 10:e0131766.	LEAK OXPHOS ET	F N S Gp NS ROX	Permeabilized tissue	Rat	Skeletal muscle
Weidinger 2015 Antioxid Redox Signal	2015	Weidinger A, Müllebner A, Paier-Pourani J, Banerjee A*, Miller I, Lauterböck L, Duvigneau JC, Skulachev VP, Redl H, Kozlov AV (2015) Vicious inducible nitric oxide synthase-mitochondrial reactive oxygen species cycle accelerates inflammatory response and causes liver injury in rats. Antioxid Redox Signal 22:572-86.	LEAK OXPHOS ET	N S	Homogenate	Rat	Liver
Senyilmaz 2015 Nature	2015	Senyilmaz D, Virtue S, Xu X, Tan CY, Griffin JL, Miller AK, Vidal-Puig A, Teleman AA (2015) Regulation of mitochondrial morphology and function by stearoylation of TFR1. Nature 525:124-8.	OXPHOS ET	N S CIV NS	Permeabilized tissue	Drosophila
Sundstroem 2015 PhD Thesis	2015	Sundstrøm T (2015) Experimental modeling and novel therapeutic strategies in melanoma brain metastasis. PhD Thesis 1-146.	ET	N S NS ROX		Mouse	Nervous system
Jiroutkova 2015 Crit Care	2015	Jiroutková K, Krajčová A, Ziak J, Fric M, Waldauf P, Džupa V, Gojda J, Němcova-Fürstová V, Kovář J, Elkalaf M, Trnka J, Duška F (2015) Mitochondrial function in skeletal muscle of patients with protracted critical illness and ICU-acquired weakness. Crit Care 19:448.	LEAK OXPHOS ET	N S Gp CIV NS Other combinations ROX	Homogenate	Human	Skeletal muscle
Johnson 2015 Aging Cell	2015	Johnson ML, Lalia AZ, Dasari S, Pallauf M, Fitch M, Hellerstein MK, Lanza IR (2015) Eicosapentaenoic acid but not docosahexaenoic acid restores skeletal muscle mitochondrial oxidative capacity in old mice. Aging Cell 14:734-43.	LEAK OXPHOS	F N S NS ROX	Isolated mitochondria	Mouse	Skeletal muscle
Gram 2015 J Physiol	2015	Gram M, Vigelsø A, Yokota T, Helge JW, Dela F, Hey-Mogensen M (2015) Skeletal muscle mitochondrial H₂O₂ emission increases with immobilization and decreases after aerobic training in young and older men. J Physiol 593:4011-27.	LEAK OXPHOS	N S	Isolated mitochondria	Human	Skeletal muscle
Mourier 2015 J Cell Biol	2015	Mourier A, Motori E, Brandt T, Lagouge M, Atanassov I, Galinier A, Rappl G, Brodesser S, Hultenby K, Dieterich C, Larsson NG (2015) Mitofusin 2 is required to maintain mitochondrial coenzyme Q levels. J Cell Biol 208:429-42.	LEAK OXPHOS ET	N S Gp Other combinations	Permeabilized cells Isolated mitochondria	Mouse	Heart Fibroblast
Kilbaugh 2015 Exp Neurol	2015	Kilbaugh TJ, Karlsson M, Byro M, Bebee A, Ralston J, Sullivan S, Duhaime AC, Hansson MJ, Elmér E, Margulies SS (2015) Mitochondrial bioenergetic alterations after focal traumatic brain injury in the immature brain. Exp Neurol 271:136-144.	LEAK ROUTINE OXPHOS ET	N S CIV NS ROX	Permeabilized tissue Homogenate	Pig	Nervous system
Lim 2015 Am J Cancer Res	2015	Lim SC, Carey KT, McKenzie M (2015) Anti-cancer analogues ME-143 and ME-344 exert toxicity by directly inhibiting mitochondrial NADH: ubiquinone oxidoreductase (Complex I). Am J Cancer Res 5:689-701.	LEAK ROUTINE OXPHOS	N S	Permeabilized cells Isolated mitochondria Intact cells	Human	Kidney Other cell lines HEK HeLa Fibroblast
Chekulayev 2015 Biochem Biophys Rep	2015	Chekulayev V, Mado K, Shevchuk I, Koit A, Kaldma A, Klepinin A, Timohhina N, Tepp K, Kandashvili M, Ounpuu L, Heck K, Truu L, Planken A, Valvere V, Kaambre T (2015) Metabolic remodeling in human colorectal cancer and surrounding tissues: alterations in regulation of mitochondrial respiration and metabolic fluxes. Biochem Biophys Rep 4:111-25.	OXPHOS	N S CIV ROX	Permeabilized tissue	Human	Endothelial;epithelial;mesothelial cell
Duicu 2015 Biomed Res Int	2015	Duicu OM, Lighezan R, Sturza A, Ceausu RA, Borza C, Vaduva A, Noveanu L, Gaspar M, Ionac A, Feier H, Muntean DM, Mornos C (2015) Monoamine oxidases as potential contributors to oxidative stress in diabetes: time for a study in patients undergoing heart surgery. Biomed Res Int 2015:515437.	LEAK OXPHOS ET	N S ROX	Permeabilized tissue	Human	Heart
Tomsik 2015 J Organomet Chem	2015	Tomsík P, Muthna D, Rezacova M, Micuda S, Cmielova J, Hroch M, Endlicher R, Cervinkova Z, Rudolf E, Hann S, Stíbal D, Therrien B, Süss-Fink G (2015) [(p-MeC₆H₄Prⁱ)₂Ru₂(SC₆H₄-p-Bu^t)₃]Cl (diruthenium-1), a dinuclear arene ruthenium compound with very high anticancer activity: An in vitro and in vivo study. J Organomet Chem 782:42-51.	LEAK OXPHOS	N S	Isolated mitochondria	Rat	Liver
Ehinger 2015 J Neurol	2015	Ehinger JK, Morota S, Hansson MJ, Paul G, Elmér E (2015) Mitochondrial dysfunction in blood cells from amyotrophic lateral sclerosis patients. J Neurol 262:1493-503.	LEAK ROUTINE OXPHOS ET	N S CIV NS ROX	Permeabilized cells Intact cells	Human	Blood cells Lymphocyte Platelet
Herbst 2015 J Physiol	2015	Herbst EA, Holloway GP (2015) Permeabilization of brain tissue in situ enables multi-region analysis of mitochondrial function in a single mouse brain. J Physiol 593:787-801.	LEAK OXPHOS	N S NS	Permeabilized tissue Isolated mitochondria	Mouse	Nervous system
Labieniec-Watala 2015 Int J Pharm Sci Res	2015	Labieniec-Watala M, Przygodzki T, Siewiera K, Podsedek A, Watala C (2015) Facts and artifacts in the evaluation of the anti-diabetic activity of spent hop extract in rat hearts in the “experimental model of diabetes. Int J Pharm Sci Res 1:106.	LEAK OXPHOS ET	S ROX	Isolated mitochondria	Rat	Heart
Abou-Hamdan 2015 Methods Enzymol	2015	Abou-Hamdan A, Guedouari-Bounihi H, Lenoir V, Andriamihaja M, Blachier F, Bouillaud F (2015) Oxidation of H2S in mammalian cells and mitochondria. Methods Enzymol 554:201-28.	OXPHOS	N S CIV	Intact cells Homogenate Isolated mitochondria	Human Pig Mouse Rat	Heart Nervous system Liver Kidney Genital CHO Neuroblastoma Fibroblast
Kelly 2015 Biotechnol J	2015	Kelly PS, Breen L, Gallagher C, Kelly S, Henry M, Lao NT, Meleady P, O'Gorman D, Clynes M, Barron N (2015) Re-programming CHO cell metabolism using miR-23 tips the balance towards a highly productive phenotype. Biotechnol J 10:1029-40.	LEAK ROUTINE OXPHOS ET	N S CIV NS ROX	Intact cells Permeabilized cells		CHO
Beier 2015 FASEB J	2015	Beier UH, Angelin A, Akimova T, Wang L, Liu Y, Xiao H, Koike MA, Hancock SA, Bhatti TR, Han R, Jiao J, Veasey SC, Sims CA, Baur JA, Wallace DC, Hancock WW (2015) Essential role of mitochondrial energy metabolism in Foxp3⁺ T-regulatory cell function and allograft survival. FASEB J 29:2315-26. https://doi.org/10.1096/fj.14-268409	LEAK OXPHOS ET	N S NS ROX	Homogenate	Mouse	Nervous system
Hagl 2015 J Alzheimers Dis	2015	Hagl S, Grewal R, Ciobanu I, Helal A, Khayyal MT, Muller WE, Eckert GP (2015) Rice bran extract compensates mitochondrial dysfunction in a cellular model of early Alzheimer’s disease. J Alzheimers Dis 43:927-38.	LEAK OXPHOS ET	N S CIV NS ROX	Permeabilized cells	Rat	Nervous system Kidney Other cell lines
Joergensen 2015 J Cereb Blood Flow Metab	2015	Jørgensen T, Grunnet N, Quistorff B (2015) One-year high fat diet affects muscle-but not brain mitochondria. J Cereb Blood Flow Metab 35:943-50.	LEAK OXPHOS	F N S Other combinations	Isolated mitochondria	Rat	Skeletal muscle Nervous system
Karadayian 2015 Neuroscience	2015	Karadayian AG, Bustamante J, Czerniczyniec A, Lombardi P, Cutrera RA, Lores-Arnaiz S (2015) Alcohol hangover induces mitochondrial dysfunction and free radical production in mouse cerebellum. Neuroscience 304:47-59.	LEAK OXPHOS	N S Other combinations	Isolated mitochondria	Mouse	Nervous system
Dungel 2015 Free Radic Biol Med	2015	Dungel P, Perlinger M, Weidinger A, Redl H, Kozlov AV (2015) The cytoprotective effect of nitrite is based on the formation of dinitrosyl iron complexes. Free Radic Biol Med 89:300-10.	LEAK OXPHOS ET	N S	Isolated mitochondria	Rat	Liver
Drechsler 2015 Intensive Care Medicine Experimental	2015	Drechsler S, Weixelbaumer KM, Weidinger A, Raeven P, Khadem A, Redl H, van Griensven M, Bahrami S, Remick D, Kozlov A, Osuchowski MF (2015) Why do they die? Comparison of selected aspects of organ injury and dysfunction in mice surviving and dying in acute abdominal sepsis. Intensive Care Medicine Experimental 3:12.	LEAK OXPHOS ET	N S	Homogenate	Mouse	Liver Kidney
Moore 2015 PhD Thesis	2015	Moore D (2015) Biostabilization of lipid bilayers: dealing with water stress in embryos of Artemia franciscana. PhD Thesis 1-111.	LEAK OXPHOS ET	S	Isolated mitochondria	Rat	Liver
Bonhoure 2015 Genes Dev	2015	Bonhoure N, Byrnes A, Moir RD, Hodroj W, Preitner F, Praz V, Marcelin G, Chua SC Jr, Martinez-Lopez N, Singh R, Moullan N, Auwerx J, Willemin G, Shah H, Hartil K, Vaitheesvaran B, Kurland I, Hernandez N, Willis IM1 (2015) Loss of the RNA polymerase III repressor MAF1 confers obesity resistance. Genes Dev 29:934-47.	OXPHOS	N S NS	Homogenate	Mouse	Liver
Schirris 2015 Cell Metab	2015	Schirris TJ, Renkema GH, Ritschel T, Voermans NC, Bilos A, van Engelen BG, Brandt U, Koopman WJ, Beyrath JD, Rodenburg RJ, Willems PH, Smeitink JA, Russel FG (2015) Statin-induced myopathy is associated with mitochondrial complex III inhibition. Cell Metab 22:399-407.	ROUTINE OXPHOS ET	N S Gp CIV NS ROX	Permeabilized cells	Human Mouse	Skeletal muscle Other cell lines
Truksa 2015 Antioxid Redox Signal	2015	Truksa J, Dong L, Rohlena J, Stursa J, Vondrusova M, Goodwin J, Nguyen M, Kluckova K, Rychtarcikova Z, Lettlova S, Spacilova J, Stapelberg M, Zoratti M, Neuzil J (2015) Mitochondrially targeted vitamin E succinate modulates expression of mitochondrial DNA transcripts and mitochondrial biogenesis. Antioxid Redox Signal 22:883-900.	ROUTINE	S	Intact cells	Human Mouse	Genital Other cell lines
Singh 2015 Free Radic Biol Med	2015	Singh P, Sharma R, McElhanon K, Allen CD, Megyesi JK, Beneš H, Singh SP (2015) Sulforaphane protects the heart from doxorubicin-induced toxicity. Free Radic Biol Med 86:90-101.	OXPHOS	N S CIV ROX	Permeabilized tissue	Mouse	Heart Other cell lines
Kucera 2015 Oxid Med Cell Longev	2015	Kucera O, Mezera V, Moravcova A, Endlicher R, Lotkova H, Drahota Z, Cervinkova Z (2015) In vitro toxicity of epigallocatechin gallate in rat liver mitochondria and hepatocytes. Oxid Med Cell Longev 2015:476180.	LEAK OXPHOS	N S	Isolated mitochondria Intact cells	Rat	Liver
Cell ergometry	2015	Gnaiger E (2015) Cell ergometry and OXPHOS. Mitochondr Physiol Network 2015-01-18.	LEAK OXPHOS ET	N S NS ROX
Christiansen 2015 J Vet Med Sci	2015	Christiansen LB, Dela F, Koch J, Yokota T (2015) Tissue-specific and substrate-specific mitochondrial bioenergetics in feline cardiac and skeletal muscles. J Vet Med Sci 77:669-75.	LEAK OXPHOS ET	F N S CIV NS Other combinations ROX	Permeabilized tissue	Cat	Heart Skeletal muscle
Lark 2015 Front Physiol	2015	Lark DS, Reese LR, Ryan TE, Torres MJ, Smith CD, Lin CT, Neufer PD (2015) Protein kinase A governs oxidative phosphorylation kinetics and oxidant emitting potential at complex I. https://doi.org/10.3389/fphys.2015.00332	LEAK ET OXPHOS	N S	Permeabilized tissue Isolated mitochondria	Mouse	Skeletal muscle Liver
Caito 2015 Antioxid Redox Signal	2015	Caito SW, Aschner M (2015) Mitochondrial redox dysfunction and environmental exposures. Antioxid Redox Signal 23:578-95.	OXPHOS	N S CIV	Isolated mitochondria	Human Mouse Rat Bovines Drosophila Fishes Hexapods	Heart Nervous system Liver Kidney Lung;gill Endothelial;epithelial;mesothelial cell
Morato 2015 Cell Death Differ	2015	Morató L, Ruiz M, Boada J, Calingasan NY, Galino J, Guilera C, Jové M, Naudí A, Ferrer I, Pamplona R, Serrano M, Portero-Otín M, Beal MF, Fourcade S, Pujol A (2015) Activation of sirtuin 1 as therapy for the peroxisomal disease adrenoleukodystrophy. Cell Death Differ 22:1742-53.	LEAK OXPHOS	N S NS ROX	Permeabilized tissue	Mouse	Nervous system
Haegler 2015 Toxicology	2015	Haegler P, Grünig D, Berger B, Krähenbühl S, Bouitbir J (2015) Impaired mitochondrial function in HepG2 cells treated with hydroxy-cobalamin[c-lactam]: A cell model for idiosyncratic toxicity. Toxicology 336:48-58.	OXPHOS	N S CIV NS		Human	Liver Other cell lines
Chin 2015 US Patent	2015	Chin MT, Chien WM, Dinca A (2015) Modified tafazzin proteins and methods of making and using the same. US Patent US20150203827 A1.	OXPHOS	N S CIV	Permeabilized tissue	Mouse	Skeletal muscle
Hals 2015 PLoS One	2015	Hals IK, Bruerberg SG, Ma Z, Scholz H, Björklund A, Grill V (2015) Mitochondrial respiration in insulin-producing β-cells: general characteristics and adaptive effects of hypoxia. PLoS One 10:e0138558.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Permeabilized cells Intact cells	Rat	Islet cell;pancreas;thymus Other cell lines
Clemens 2015 Brain	2015	Clemens LE, Weber JJ, Wlodkowski TT, Yu-Taeger L, Michaud M, Calaminus C, Eckert SH, Gaca J, Weiss A, Magg JC, Jansson EK, Eckert GP, Pichler BJ, Bordet T, Pruss RM, Riess O, Nguyen HP (2015) Olesoxime suppresses calpain activation and mutant huntingtin fragmentation in the BACHD rat. Brain 138:3632-53.	LEAK OXPHOS ET	N S CIV NS ROX	Isolated mitochondria	Rat	Nervous system
Ziak 2015 Mitochondrion	2015	Ziak J, Krajcova A, Jiroutkova K, Nemcova V, Dzupa V, Duska F (2015) Assessing the function of mitochondria in cytosolic context in human skeletal muscle: Adopting high-resolution respirometry to homogenate of needle biopsy tissue samples. Mitochondrion 21:106-12.	LEAK OXPHOS ET	N S NS ROX	Homogenate Isolated mitochondria	Human	Skeletal muscle
Konopka 2015 Diabetes	2015	Konopka AR, Asante A, Lanza IR, Robinson MM, Johnson ML, Dalla Man C, Cobelli C, Amols MH, Irving BA, Nair KS (2015) Defects in mitochondrial efficiency and H₂O₂ emissions in obese women are restored to a lean phenotype with aerobic exercise training. Diabetes 64:2104-15.	LEAK OXPHOS ET	N S NS ROX	Isolated mitochondria	Human	Skeletal muscle
Hey-Mogensen 2015 J Physiol	2015	Hey-Mogensen M, Gram M, Jensen MB, Lund MT, Hansen CN, Scheibye-Knudsen M, Bohr VA, Dela F (2015) A novel method for determining human ex vivo submaximal skeletal muscle mitochondrial function. J Physiol 593:3991-4010.	LEAK OXPHOS	N S	Isolated mitochondria	Human	Skeletal muscle
Kilbaugh 2015 PLoS One	2015	Kilbaugh TJ, Lvova M, Karlsson M, Zhang Z, Leipzig J, Wallace DC, Margulies SS (2015) Peripheral blood mitochondrial DNA as a biomarker of cerebral mitochondrial dysfunction following traumatic brain injury in a porcine model. PLoS One 10:e0130927.	LEAK OXPHOS	N S NS	Homogenate	Pig	Nervous system
Soares 2015 PLoS One	2015	Soares JB, Gaviraghi A, Oliveira MF (2015) Mitochondrial physiology in the major arbovirus vector Aedes aegypti: substrate preferences and sexual differences define respiratory capacity and superoxide production. PLoS One 10:e0120600.	LEAK OXPHOS ET	N S Gp NS Other combinations ROX	Permeabilized tissue Isolated mitochondria	Hexapods	Skeletal muscle
Errea 2015 J Neuroinflammation	2015	Errea O, Moreno B, Gonzalez-Franquesa A, Garcia-Roves PM, Villoslada P (2015) The disruption of mitochondrial axonal transport is an early event in neuroinflammation. J Neuroinflammation 12:152.	LEAK OXPHOS ET	N S CIV NS ROX	Homogenate	Mouse	Nervous system
Darrah-Wiedemeier 2015 Graduate Theses and Dissertations	2015	Darrah-Wiedemeier KL (2015) The physiological effects of the seed treatment Stamina on maize seedling length, ADP:O ratios, and respiration rates. Graduate Theses and Dissertations Paper 14673:55 pp.	LEAK OXPHOS	S	Isolated mitochondria	Plants
Jeger 2015 BioMed Res Internat	2015	Jeger V, Brandt S, Porta F, Jakob SM, Takala J, Djafarzadeh S (2015) Dose response of Endotoxin on hepatocyte and muscle mitochondrial respiration in vitro. BioMed Res Internat Article ID 353074:1-13.	LEAK ROUTINE OXPHOS ET	N S CIV NS ROX	Permeabilized cells Isolated mitochondria Intact cells	Human	Skeletal muscle Liver Other cell lines
Agil 2015 J Pineal Res	2015	Agil A, El-Hammadi M, Jiménez-Aranda A, Tassi M, Abdo W, Fernández-Vázquez G, Reiter RJ (2015) Melatonin reduces hepatic mitochondrial dysfunction in diabetic obese rats. J Pineal Res 59:70-9.	LEAK OXPHOS	S	Isolated mitochondria	Rat	Liver
Schwarzkopf 2015 Neuroscience	2015	Schwarzkopf TM, Koch K, Klein J (2015) Reduced severity of ischemic stroke and improvement of mitochondrial function after dietary treatment with the anaplerotic substance triheptanoin. Neuroscience 300:201-9.	LEAK OXPHOS ET	N S CIV NS ROX	Isolated mitochondria	Mouse	Nervous system
Vincent 2015 Front Physiol	2015	Vincent G, Lamon S, Gant N, Vincent PJ, MacDonald JR, Markworth JF, Edge JA, Hickey AJ (2015) Changes in mitochondrial function and mitochondria associated protein expression in response to 2-weeks of high intensity interval training. Front Physiol 6:51.	LEAK OXPHOS ET	N S ROX	Permeabilized tissue	Human	Skeletal muscle
Gainutdinov 2015 Arch Biochem Biophys	2015	Gainutdinov T, Molkentin JD, Siemen D, Ziemer M, Debska-Vielhaber G, Vielhaber S, Gizatullina Z, Orynbayeva Z, Gellerich FN (2015) Knockout of cyclophilin D in Ppif(-/-) mice increases stability of brain mitochondria against Ca(2+) stress. Arch Biochem Biophys 579:40-6.	LEAK OXPHOS	N S ROX	Isolated mitochondria	Mouse	Nervous system
Lauritzen 2015 Am J Physiol Heart Circ Physiol	2015	Lauritzen KH, Kleppa L, Aronsen JM, Eide L, Carlsen H, Haugen ØP, Sjaastad I, Klungland A, Rasmussen LJ, Attramadal H, Storm-Mathisen J, Bergersen LH (2015) Impaired dynamics and function of mitochondria caused by mtDNA toxicity leads to heart failure. Am J Physiol Heart Circ Physiol 309:H434-49.		S	Homogenate	Mouse	Heart
Singh 2015 Biochim Biophys Acta	2015	Singh F, Charles AL, Schlagowski AI, Bouitbir J, Bonifacio A, Piquard F, Krähenbühl S, Geny B, Zoll J (2015) Reductive stress impairs myoblasts mitochondrial function and triggers mitochondrial hormesis. Biochim Biophys Acta 1853:1574-85.	LEAK OXPHOS	N S NS	Permeabilized tissue	Mouse	Skeletal muscle
Bock 2015 Thesis	2015	Bock UB (2015) Auswirkung von normobarer Hyperoxie auf die mitochondriale Atmung von Alveolarmakrophagen. Dissertation p80.	LEAK ROUTINE OXPHOS ET	N S CIV NS ROX	Permeabilized cells Intact cells	Mouse	Lung;gill Macrophage-derived
Kake-Guena 2015 J Exp Zool A Ecol Genet Physiol	2015	Kake-Guena SA, Touisse K, Vergilino R, Dufresne F, Blier PU, Lemieux H1 (2015) Assessment of mitochondrial functions in Daphnia pulex clones using high-resolution respirometry. J Exp Zool A Ecol Genet Physiol 323:292-300.	LEAK OXPHOS	N S CIV NS ROX	Permeabilized tissue	Crustaceans
Muellebner 2015 Biomolecules	2015	Müllebner A, Moldzio R, Redl H, Kozlov AV, Duvigneau JC (2015) Heme degradation by heme oxygenase protects mitochondria but induces ER stress via formed bilirubin. Biomolecules 5:679-701.	OXPHOS	S	Isolated mitochondria	Rat	Liver
Gnaiger 2015 Scand J Med Sci Sports	2015	Gnaiger E, Boushel R, Søndergaard H, Munch-Andersen T, Damsgaard R, Hagen C, Díez-Sánchez C, Ara I, Wright-Paradis C, Schrauwen P, Hesselink M, Calbet JAL, Christiansen M, Helge JW, Saltin B (2015) Mitochondrial coupling and capacity of oxidative phosphorylation in skeletal muscle of Inuit and caucasians in the arctic winter. https://doi.org/10.1111/sms.12612	LEAK OXPHOS ET	F N S ROX	Permeabilized tissue	Human	Skeletal muscle
Irving 2015 J Clin Endocrinol Metab	2015	Irving BA, Lanza IR, Henderson GC, Rao RR, Spiegelman BM, Nair KS (2015) Combined training enhances skeletal muscle mitochondrial oxidative capacity independent of age. J Clin Endocrinol Metab 100:1654-63.	LEAK OXPHOS ET	N S NS	Isolated mitochondria	Human	Skeletal muscle
Skemiene 2015 FEBS J	2015	Skemiene K, Liobikas J, Borutaite V (2015) Anthocyanins as substrates for mitochondrial complex I - protective effect against heart ischemic injury. FEBS J 282:963-71.	LEAK OXPHOS	N S	Isolated mitochondria	Rat	Heart
Hollis 2015 Proc Natl Acad Sci U S A	2015	Hollis F, van der Kooij MA, Zanoletti O, Lozano L, Cantó C, Sandi C (2015) Mitochondrial function in the brain links anxiety with social subordination. Proc Natl Acad Sci U S A 112:15486-91.	OXPHOS ET	N S NS ROX	Homogenate	Rat	Nervous system
Hejzlarova 2015 Biochem J	2015	Hejzlarová K, Kaplanová V, Nůsková H, Kovářová N, Ješina P, Drahota Z, Mráček T, Seneca S, Houštěk J (2015) Alteration of structure and function of ATP synthase and cytochrome c oxidase by lack of Fo-a and Cox3 subunits caused by mitochondrial DNA 9205delTA mutation. Biochem J 466:601-11.	LEAK OXPHOS ET	S CIV	Permeabilized cells Isolated mitochondria	Human	Other cell lines
Richman 2015 PLoS Genet	2015	Richman TR, Ermer JA, Davies SM, Perks KL, Viola HM, Shearwood AM, Hool LC, Rackham O, Filipovska A (2015) Mutation in MRPS34 compromises protein synthesis and causes mitochondrial dysfunction. PLoS Genet 11:e1005089.	LEAK OXPHOS	N S CIV	Isolated mitochondria	Mouse	Heart Liver
Lehtola 2015 Master's Thesis	2015	Lehtola A (2015) Main protein component of high density lipoprotein, apolipoprotein A1, modulates leukocyte cell respiration. Master's Thesis 1-44.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Intact cells Permeabilized cells	Human	Blood cells Other cell lines Lymphocyte
Wahrheit 2015 Eng Life Sci	2015	Wahrheit J, Nonnenmacher Y, Sperber S, Heinzle E (2015) High-throughput respiration screening of single mitochondrial substrates using permeabilized CHO cells highlights control of mitochondria metabolism. Eng Life Sci 15:184-94.	LEAK OXPHOS	N S ROX	Permeabilized cells	Other mammals	Genital
Sjoevall 2015 US Patent	2015	Sjövall F, Ehinger J, Hansson M, Elmer E, Batcheller DG (2018) Mitochondrial toxicity test. US Patent US20150253306 A1.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Intact cells Permeabilized cells	Human	Blood cells Macrophage-derived Platelet
Antoun 2015 JIMD Rep	2015	Antoun G, McBride S, Vanstone JR, Naas T, Michaud J, Redpath S, McMillan HJ, Brophy J, Daoud H, Chakraborty P, Dyment D, Holcik M, Harper ME, Lines MA (2015) Detailed biochemical and bioenergetic characterization of FBXL4-related encephalomyopathic mitochondrial DNA depletion. JIMD Rep 27:1-9.	LEAK OXPHOS ET	F N S CIV NS ROX	Permeabilized tissue	Human	Skeletal muscle
Angebault 2015 Am J Hum Genet	2015	Angebault C, Guichet PO, Talmat-Amar Y, Charif M, Gerber S, Fares-Taie L, Gueguen N, Halloy F, Moore D, Amati-Bonneau P, Manes G, Hebrard M, Bocquet B, Quiles M, Piro-Mégy C, Teigell M, Delettre C, Rossel M, Meunier I, Preising M, Lorenz B, Carelli V, Chinnery PF, Yu-Wai-Man P, Kaplan J, Roubertie A, Barakat A, Bonneau D, Reynier P, Rozet JM, Bomont P, Hamel CP, Lenaers G (2015) Recessive mutations in RTN4IP1 cause isolated and syndromic optic neuropathies. Am J Hum Genet 97:754-60.		N S CIV NS ROX		Human	Endothelial;epithelial;mesothelial cell Fibroblast
Khera 2015 Placenta	2015	Khera A, Dong LF, Holland OJ, Vanderlelie J, Pasdar EA, Neuzil J, Perkins AV (2015) Selenium supplementation induces mitochondrial biogenesis in trophoblasts. Placenta 36:863-9.	LEAK ROUTINE OXPHOS ET	N S CIV	Permeabilized cells Intact cells	Human	Genital Other cell lines
Schrauwen-Hinderling 2015 Antioxid Redox Signal	2015	Schrauwen-Hinderling VB, Kooi ME, Schrauwen P (2015) Mitochondrial function and diabetes; consequences for skeletal and cardiac muscle metabolism. Antioxid Redox Signal 24:39-51.	LEAK OXPHOS	F N S CIV	Permeabilized tissue Isolated mitochondria	Human	Heart Skeletal muscle
Hagl 2015 Molecules	2015	Hagl S, Berressem D, Bruns B, Sus N, Frank J, Eckert GP (2015) Beneficial Effects of Ethanolic and Hexanic Rice Bran Extract on Mitochondrial Function in PC12 Cells and the Search for Bioactive Components. Molecules 20(9):16524-39.	LEAK ROUTINE OXPHOS ET	N S CIV NS ROX	Permeabilized cells	Rat	Nervous system Other cell lines
Acosta 2015 Obesity (Silver Spring)	2015	Acosta A, Camilleri M, Shin A, Vazquez-Roque MI, Iturrino J, Lanza IR, Nair KS, Burton D, O'Neill J, Eckert D, Carlson P, Vella A, Zinsmeister AR (2015) Association of UCP-3 rs1626521 with obesity and stomach functions in humans. Obesity (Silver Spring) 23:898-906.	LEAK OXPHOS	N S NS	Isolated mitochondria	Human	Skeletal muscle
Hendricks 2015 Thesis	2015	Hendricks EW (2015) The impact of aging and estrogen therapy on synaptic mitochondrial bioenergetics in an Alzheimer's mouse model. Master Thesis 1-67.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Permeabilized cells Isolated mitochondria Intact cells	Mouse	Nervous system
Silachev 2015 Chem Biol Interact	2015	Silachev DN, Gulyaev MV, Zorova LD, Khailova LS, Gubsky LV, Pirogov YA, Plotnikov EY, Sukhikh GT, Zorov DB (2015) Magnetic resonance spectroscopy of the ischemic brain under lithium treatment. Link to mitochondrial disorders under stroke. Chem Biol Interact 237:175-82.	LEAK OXPHOS	S	Isolated mitochondria	Rat	Nervous system
Flatters 2015 Prog Mol Biol Transl Sci	2015	Flatters SJ (2015) The contribution of mitochondria to sensory processing and pain. Prog Mol Biol Transl Sci 131:119-46.	OXPHOS ET	N S CIV NS	Homogenate Isolated mitochondria	Rat	Nervous system
Houben 2015 Mitochondrion	2015	Houben R, Leleu C, Fraipont A, Serteyn D, Votion DM (2015) Determination of muscle mitochondrial respiratory capacity in Standardbred racehorses as an aid to predicting exertional rhabdomyolysis. Mitochondrion 24:99-104.	OXPHOS ET	N S NS ROX	Permeabilized tissue	Horse	Skeletal muscle
Diana 2015 Surg Innov	2015	Diana M, Noll E, Diemunsch P, Moussallieh FM, Namer IJ, Charles AL, Lindner V, Agnus V, Geny B, Marescaux J (2015) Metabolism-guided bowel resection: potential role and accuracy of instant capillary lactates to identify the optimal resection site. Surg Innov 22:453-61.	LEAK OXPHOS	N S CIV		Pig	Endothelial;epithelial;mesothelial cell
Teh 2015 Oncogene	2015	Teh JT, Zhu WL, Ilkayeva OR, Li Y, Gooding J, Casey PJ, Summers SA, Newgard CB, Wang M (2015) Isoprenylcysteine carboxylmethyltransferase regulates mitochondrial respiration and cancer cell metabolism. Oncogene 34:3296-304.	OXPHOS	N S DQ CIV ROX	Permeabilized cells	Human	Other cell lines
Chu 2015 Liver Transpl	2015	Chu MJ, Hickey AJ, Jiang Y, Petzer A, Bartlett AS, Phillips AR (2015) Mitochondrial dysfunction in steatotic rat livers occurs because a defect in complex I makes the liver susceptible to prolonged cold ischemia. Liver Transpl 21:396-407.	LEAK OXPHOS ET	N S ROX	Homogenate	Rat	Liver
Crombie 2015 Biochem Biophys Rep	2015	Crombie DE, van Bergena N, Davidsona KC, Anjomani Virmounib S, Mckelviec PA, Chrysostomoua V, Conquesta A, Corbend LA, Pookb MA, Kulkarnia T, Trouncea IA, Peraf MF, Delatyckid MB, Pébaya A (2015) Characterization of the retinal pigment epithelium in Friedreich ataxia. Biochem Biophys Rep 4:141–7.	LEAK OXPHOS ET	N S NS ROX	Permeabilized cells	Human	Nervous system Endothelial;epithelial;mesothelial cell Stem cells
Pasdar 2015 PLoS One	2015	Pasdar EA, Smits M, Stapelberg M, Bajzikova M, Stantic M, Goodwin J, Yan B, Stursa J, Kovarova J, Sachaphibulkij K, Bezawork-Geleta A, Sobol M, Filimonenko A, Tomasetti M, Zobalova R, Hozak P, Dong LF, Neuzil J (2015) Characterisation of mesothelioma-initiating cells and their susceptibility to anti-cancer agents. PLoS One 10:e0119549.	LEAK ROUTINE OXPHOS ET	N S NS	Permeabilized cells Intact cells	Human Mouse	Endothelial;epithelial;mesothelial cell Other cell lines
Boushel 2015 Scand J Med Sci Sports	2015	Boushel R, Gnaiger E, Larsen FJ, Helge JW, Gonzalez-Alonso J, Ara I, Munch-Andersen T, van Hall G, Søndergaard H, Saltin B, Calbet JAL (2015) Maintained peak leg and pulmonary V_O2 despite substantial reduction in muscle mitochondrial capacity. Scand J Med Sci Sports 25 (Suppl 4):135–43.	OXPHOS	F N S NS	Intact organ Permeabilized tissue	Human	Skeletal muscle
Kluckova 2015 Methods Mol Biol	2015	Kluckova K, Dong L, Bajzikova M, Rohlena J, Neuzil J (2015) Evaluation of respiration of mitochondria in cancer cells exposed to mitochondria-targeted agents. Methods Mol Biol 1265:181-94.	LEAK OXPHOS ET	N S NS ROX	Permeabilized cells Homogenate Intact cells	Mouse	Endothelial;epithelial;mesothelial cell Genital Other cell lines
Rodrigues 2016 Biochem J	2015	Rodrigues MF, Obre E, Melo FH, Santos-Jr GC, Galina A, Jasiulionis MG, Rossignol R, Rumjanek FD, Amoedo ND (2016) Enhanced OXPHOS, glutaminolysis and beta-oxidation constitute the metastatic phenotype of melanoma cells. https://doi.org/10.1042/BJ20150645	LEAK ROUTINE OXPHOS ET	F N S ROX	Permeabilized cells Intact cells	Mouse	Endothelial;epithelial;mesothelial cell Other cell lines
Kang 2015 Int J Clin Exp Med	2015	Kang M, Zhao L, Ren M, Deng M, Li C (2015) Reduced metallothionein expression induced by Zinc deficiency results in apoptosis in hepatic stellate cell line LX-2. Int J Clin Exp Med 8:20603-9.	LEAK OXPHOS	S	Isolated mitochondria	Human	Liver Other cell lines
Grabez 2015 J Anim Sci	2015	Grabež V, Kathri M, Phung V, Moe KM, Slinde E, Skaugen M, Saarem K, Egelandsdal B (2015) Protein expression and oxygen consumption rate of early postmortem mitochondria relate to meat tenderness. J Anim Sci 93:1967-79.	LEAK OXPHOS ET	F N S NS Other combinations ROX	Permeabilized tissue	Bovines	Skeletal muscle
Fliri 2015 US Patent	2015	Fliri HG, Ford RL, Scowen DA, Batcheller DG, Ehinger J, Elmér E, Hansson MJ, Sjövall F (2015) Protected succinates for enhancing mitochondrial atp-production. US Patent US20150259317 A1.	ET	S NS ROX	Permeabilized cells Intact cells	Human	Blood cells Platelet
Burtscher 2015 Mitochondrion	2015	Burtscher J, Zangrandi L, Schwarzer C, Gnaiger E (2015) Differences in mitochondrial function in homogenated samples from healthy and epileptic specific brain tissues revealed by high-resolution respirometry. Mitochondrion 25:104-12.	LEAK OXPHOS ET	N S CIV NS ROX	Permeabilized tissue Homogenate	Mouse	Nervous system
Arden 2015 Webvision	2015	Arden GB, Ramsey DJ (2015) Diabetic retinopathy and a novel treatment based on the biophysics of rod photoreceptors and dark adaptation. In: Kolb H, Fernandez E, Nelson R, eds. Webvision: The organization of the retina and visual system [Internet]. Salt Lake City (UT): University of Utah Health Sciences Center; 1995-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK310272/		S
McCommis 2015 Cell Metab	2015	McCommis KS, Chen Z, Fu X, McDonald WG, Colca JR, Kletzien RF, Burgess SC, Finck BN (2015) Loss of mitochondrial pyruvate carrier 2 in the liver leads to defects in gluconeogenesis and compensation via pyruvate-alanine cycling. Cell Metab 22:682-94.	OXPHOS	N S	Permeabilized cells Isolated mitochondria	Mouse	Liver
Zelenka 2015 Oxid Med Cell Longev	2015	Zelenka J, Dvořák A, Alán L (2015) L-lactate protects skin fibroblasts against aging-associated mitochondrial dysfunction via mitohormesis. Oxid Med Cell Longev 2015:351698.	LEAK ROUTINE ET	N S	Isolated mitochondria Intact cells	Rat	Liver Endothelial;epithelial;mesothelial cell Fibroblast
Baris 2015 Am J Physiol Regul Integr Comp Physiol	2015	Baris TZ, Crawford DL, Oleksiak MF (2015) Acclimation and acute temperature effects on population differences in oxidative phosphorylation. Am J Physiol Regul Integr Comp Physiol 310:R185-96.	LEAK OXPHOS ET	N S CIV NS Other combinations ROX	Permeabilized tissue	Fishes	Heart
Zhunussova 2015 Am J Cancer Res	2015	Zhunussova A, Sen B, Friedman L, Tuleukhanov S, Brooks AD, Sensenig R, Orynbayeva Z (2015) Tumor microenvironment promotes dicarboxylic acid carrier-mediated transport of succinate to fuel prostate cancer mitochondria. Am J Cancer Res 5:1665-79.	ROUTINE ET	S	Permeabilized cells Intact cells	Human Rat	Endothelial;epithelial;mesothelial cell Genital Other cell lines
Banh 2015 Comp Biochem Physiol B Biochem Mol Biol	2015	Banh S, Wiens L, Sotiri E, Treberg JR (2015) Mitochondrial reactive oxygen species production by fish muscle mitochondria: Potential role in acute heat-induced oxidative stress. Comp Biochem Physiol B Biochem Mol Biol 191:99-107.	LEAK OXPHOS	S	Isolated mitochondria	Rat Fishes	Skeletal muscle
Hagl 2015 Neurochem Int	2015	Hagl S, Kocher A, Schiborr C, Kolesova N, Frank J, Eckert GP (2015) Curcumin micelles improve mitochondrial function in neuronal PC12 cells and brains of NMRI mice - Impact on bioavailability. Neurochem Int 89:234-42.	LEAK OXPHOS ET	N S CIV	Isolated mitochondria	Mouse	Nervous system
Tan 2015 Cell Metab	2015	Tan AS, Baty JW, Dong L, Bezawork-Geleta A, Endaya B, Goodwin J, Bajzikova M, Kovarova J, Peterka M, Yan B, Pesdar EA, Sobol M, Filimonenko A, Stuart S, Vondrusova M, Kluckova K, Sachaphibulkij K, Rohlena J, Hozak P, Truksa J, Eccles D, Haupt LM, Griffiths LR, Neuzil J, Berridge MV (2015) Mitochondrial genome acquisition restores respiratory function and tumorigenic potential of cancer cells without mitochondrial DNA. Cell Metab 21:81-94.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Permeabilized cells Isolated mitochondria Intact cells	Human Mouse	Endothelial;epithelial;mesothelial cell Genital Other cell lines
Youcef 2015 Biochem Pharmacol	2015	Youcef G, Belaidi E, Waeckel L, Fazal L, Clemessy M, Vincent MP, Zadigue G, Richer C, Alhenc-Gelas F, Ovize M, Pizard A (2015) Tissue kallikrein is required for the cardioprotective effect of cyclosporin A in myocardial ischemia in the mouse. Biochem Pharmacol 94:22-9.	LEAK OXPHOS	N S CIV	Isolated mitochondria	Mouse	Heart
Hasli 2015 Master Thesis	2015	Hasli PR (2015) Characterization of mitochondrial respiration and quality differences in diploid and triploid Atlantic salmon (Salmo salar L.) at 5 °C, 10 °C and 15 °C. Master Thesis:1-147.	LEAK OXPHOS ET	N S NS ROX	Permeabilized tissue Homogenate	Fishes	Heart Skeletal muscle
Wuest 2015 J Physiol	2015	Wüst RC, Helmes M, Stienen GJ (2015) Rapid changes in NADH and flavin autofluorescence in rat cardiac trabeculae reveal large mitochondrial complex II reserve capacity. J Physiol 593:1829-40.	LEAK OXPHOS	N S NS ROX	Permeabilized tissue	Rat	Heart
Du 2015 Aquat Toxicol	2015	Du X, Crawford DL, Oleksiak MF (2015) Effects of anthropogenic pollution on the oxidative phosphorylation pathway of hepatocytes from natural populations of Fundulus heteroclitus. Aquat Toxicol 165:231-40.	LEAK OXPHOS ET	N S CIV ROX	Permeabilized cells	Fishes	Liver
Wessels 2015 Diabetes Obes Metab	2015	Wessels B, Ciapaite J, van den Broek NM, Houten SM, Nicolay K, Prompers JJ (2015) Pioglitazone treatment restores in vivo muscle oxidative capacity in a rat model of diabetes. Diabetes Obes Metab 17:52-60.	LEAK OXPHOS ET	F N S	Isolated mitochondria	Rat	Skeletal muscle
Melo Hanchuk 2015 Cell Signal	2015	Melo Hanchuk TD, Papa PF, La Guardia PG, Vercesi AE, Kobarg J (2015) Nek5 interacts with mitochondrial proteins and interferes negatively in mitochondrial mediated cell death and respiration. Cell Signal 27:1168-77.	LEAK OXPHOS	N S CIV ROX	Permeabilized cells	Human	HEK
Imran 2015 J Neurochem	2015	Imran I, Hillert MH, Klein J (2015) Early metabolic responses to lithium/pilocarpine-induced status epilepticus in rat brain. J Neurochem 135:1007-18.	LEAK OXPHOS ET	N S CIV NS ROX	Isolated mitochondria	Rat	Nervous system
Assmann 2014 PhD Thesis	2015	Assmann N (2015) Impact of Fanconi-associated protein on the mitochonrial proteome. PhD Thesis 1-111.	LEAK ROUTINE OXPHOS ET	F N S CIV NS ROX	Permeabilized cells Intact cells	Pig	Kidney Other cell lines
Kluckova 2015 Cell Death Dis	2015	Kluckova K, Sticha M, Cerny J, Mracek T, Dong L, Drahota Z, Gottlieb E, Neuzil J, Rohlena J (2015) Ubiquinone-binding site mutagenesis reveals the role of mitochondrial complex II in cell death initiation. Cell Death Dis 6:e1749.	OXPHOS ET	S ROX	Permeabilized cells Isolated mitochondria	Other mammals	Lung;gill Other cell lines Fibroblast
Miwa 2015 Free Radic Biol Med	2015	Miwa S, Treumann A, Bell A, Vistoli G, Nelson G, Hay S, von Zglinicki T (2015) Carboxylesterase converts Amplex red to resorufin: Implications for mitochondrial H₂O₂ release assays. Free Radic Biol Med 90:173-83.	LEAK OXPHOS ET	N S ROX	Isolated mitochondria	Mouse	Liver
Aroor 2015 Diabetes	2015	Aroor AR, Habibi J, Ford DA, Nistala R, Lastra G, Manrique C, Dunham MM, Ford KD, Thyfault JP, Parks EJ, Sowers JR, Rector RS (2015) Dipeptidyl peptidase-4 inhibition ameliorates western diet-induced hepatic steatosis and insulin resistance through hepatic lipid remodeling and modulation of hepatic mitochondrial function. Diabetes 64:1988-2001.	LEAK ROUTINE OXPHOS ET	F N S NS	Isolated mitochondria	Mouse	Liver
Leman 2015 Int J Biochem Cell Biol	2015	Leman G, Gueguen N, Desquiret-Dumas V, Kane MS, Wettervald C, Chupin S, Chevrollier A, Lebre AS, Bonnefont JP, Barth M, Amati-Bonneau P, Verny C, Henrion D, Bonneau D, Reynier P, Procaccio V (2015) Assembly defects induce oxidative stress in inherited mitochondrial complex I deficiency. Int J Biochem Cell Biol 65:91-103.		N S CIV	Permeabilized cells	Human	Endothelial;epithelial;mesothelial cell Fibroblast
Harris 2015 Diabetes	2015	Harris LA, Skinner JR, Shew TM, Pietka TA, Abumrad NA, Wolins NE (2015) Perilipin 5-driven lipid droplet accumulation in skeletal muscle stimulates the expression of fibroblast growth factor 21. Diabetes 64:2757-68.	OXPHOS ET	N S NS ROX	Permeabilized tissue	Mouse	Skeletal muscle
Chausse 2015 PLoS One	2015	Chausse B, Vieira-Lara MA, Sanchez AB, Medeiros MH, Kowaltowski AJ (2015) Intermittent fasting results in tissue-specific changes in bioenergetics and redox state. PLoS One 10:e0120413.	LEAK OXPHOS	N S CIV	Isolated mitochondria	Rat	Heart Skeletal muscle Nervous system Liver
Ortiz 2015 J Pineal Res	2015	Ortiz F, Acuña-Castroviejo D, Doerrier C, Dayoub JC, López LC, Venegas C, García JA, López A, Volt H, Luna-Sánchez M, Escames G (2015) Melatonin blunts the mitochondrial/NLRP3 connection and protects against radiation-induced oral mucositis. J Pineal Res 58:34-49.	LEAK OXPHOS ET	N S	Homogenate Isolated mitochondria
Sobotka 2015 Physiol Res	2015	Sobotka O, Drahota Z, Kučera O, Endlicher R, Rauchová H, Červinková Z (2015) The effect of α-tocopheryl succinate on succinate respiration in rat liver mitochondria. Physiol Res 64 Suppl 5:S609-15.	OXPHOS ET	S	Permeabilized cells Homogenate Isolated mitochondria	Rat	Liver
Makrecka-Kuka 2015 Biomolecules	2015	Makrecka-Kuka M, Krumschnabel G, Gnaiger E (2015) High-resolution respirometry for simultaneous measurement of oxygen and hydrogen peroxide fluxes in permeabilized cells, tissue homogenate and isolated mitochondria. https://doi.org/10.3390/biom5031319	LEAK ROUTINE OXPHOS ET	N S NS ROX	Permeabilized cells Homogenate Isolated mitochondria Intact cells	Human Mouse	Heart Nervous system HEK
Porter 2015 Shock	2015	Porter C, Herndon DN, Bhattarai N, Ogunbileje JO, Szczesny B, Szabo C, Toliver-Kinsky T, Sidossis LS (2015) Severe burn injury induces thermogenically functional mitochondria in murine white adipose tissue. Shock 44:258-64.	LEAK	F N S NS Other combinations	Permeabilized tissue	Mouse	Fat
Valet 2015 US Patent	2015	Valet P, Dray C, Knauf C, Kunduzova O, Castan-Laurell I (2015) Pharmaceutical composition for use in the treatment of dysfunction associated with aging. US Patent US20150290286 A1.	OXPHOS	N S	Permeabilized tissue	Mouse	Skeletal muscle
Herbst 2015 Neuroscience	2015	Herbst EA, Holloway GP (2015) Exercise training normalizes mitochondrial respiratory capacity within the striatum of the R6/1 model of Huntington's disease. Neuroscience 303:515-23.	OXPHOS	N S NS	Permeabilized tissue	Mouse	Nervous system
Schoettl 2015 Endocrinology	2015	Schöttl T, Kappler L, Braun K, Fromme T, Klingenspor M (2015) Limited mitochondrial capacity of visceral versus subcutaneous white adipocytes in male C57BL/6N mice. Endocrinology 156:923-33.	LEAK ROUTINE OXPHOS ET	N S ROX	Permeabilized cells Isolated mitochondria Intact cells	Mouse	Fat
Boerma 2015 Radiat Res	2015	Boerma M, Singh P, Sridharan V, Tripathi P, Sharma S, Singh SP (2015) Effects of local heart irradiation in a glutathione S-transferase alpha 4-null mouse model. Radiat Res 183:610-9.	OXPHOS	N S CIV ROX	Permeabilized tissue	Mouse	Heart
Maiti 2015 PhD Thesis	2015	Maiti P (2015) The role of caseinolytic mitochondrial matrix peptidase proteolytic subunit (CLPP) in regulation of mitochondrial ribosome biogenesis in mammals. PhD Thesis 1-120.	LEAK OXPHOS ET	N S NS ROX	Isolated mitochondria	Mouse	Heart
Iftikar 2015 Comp Biochem Physiol A Mol Integr Physiol	2015	Iftikar FI, Morash AJ, Cook DG, Herbert NA, Hickey AJ (2015) Temperature acclimation of mitochondria function from the hearts of a temperate wrasse (Notolabrus celidotus). Comp Biochem Physiol A Mol Integr Physiol 184:46-55.	LEAK OXPHOS ET	N S CIV NS ROX	Permeabilized tissue	Fishes	Heart
Correa 2015 Critical Care Horizon	2015	Corrêa TD, Jakob SM, Takala J (2015) Mitochondrial function in sepsis. Critical Care Horizon 1:31-41 .	LEAK OXPHOS	N S CIV ROX	Isolated mitochondria	Pig	Liver
Kilbaugh 2015 J Am Heart Assoc	2015	Kilbaugh TJ, Sutton RM, Karlsson M, Hansson MJ, Naim MY, Morgan RW, Bratinov G, Lampe JW, Nadkarni VM, Becker LB, Margulies SS, Berg RA (2015) Persistently altered brain mitochondrial bioenergetics after apparently successful resuscitation from cardiac arrest. J Am Heart Assoc 4(9) pii: e002232.	LEAK OXPHOS ET	N S CIV NS ROX	Homogenate	Pig	Nervous system
Porter 2015 Med Sci Sports Exerc	2015	Porter C, Reidy PT, Bhattarai N, Sidossis LS, Rasmussen BB (2015) Resistance exercise training alters mitochondrial function in human skeletal muscle. Med Sci Sports Exerc 47:1922-31.	LEAK OXPHOS ET	N S NS	Permeabilized tissue	Human	Skeletal muscle
Li 2015 Sci Rep	2015	Li P, Wang B, Sun F, Li Y, Li Q, Lang H, Zhao Z, Gao P, Zhao Y, Shang Q, Liu D, Zhu Z (2015) Mitochondrial respiratory dysfunctions of blood mononuclear cells link with cardiac disturbance in patients with early-stage heart failure. Sci Rep 5:10229.	LEAK ROUTINE OXPHOS ET	N S NS	Intact cells	Human	Blood cells Lymphocyte
Jardim-Messeder 2015 New Phytol	2015	Jardim-Messeder D, Caverzan A, Rauber R, de Souza Ferreira E, Margis-Pinheiro M, Galina A (2015) Succinate dehydrogenase (mitochondrial Complex II) is a source of reactive oxygen species in plants and regulates development and stress responses. New Phytol 208:776-89.	LEAK OXPHOS	S	Isolated mitochondria	Plants
Patil 2015 J Nutr Biochem	2015	Patil YN, Dille KN, Burk DH, Cortez CC, Gettys TW (2015) Cellular and molecular remodeling of inguinal adipose tissue mitochondria by dietary methionine restriction. J Nutr Biochem 26:1235-47.	LEAK OXPHOS ET	F N S Gp ROX	Isolated mitochondria	Mouse	Skeletal muscle Liver Fat
Christiansen 2015 Am J Physiol Heart Circ Physiol	2015	Christiansen LB, Dela F, Koch J, Hansen CN, Leifsson PS, Yokota T (2015) Impaired cardiac mitochondrial oxidative phosphorylation and enhanced mitochondrial oxidative stress in feline hypertrophic cardiomyopathy. Am J Physiol Heart Circ Physiol 308:H1237-47.	LEAK OXPHOS ET	F N S CIV NS ROX	Permeabilized tissue Isolated mitochondria	Cat	Heart Skeletal muscle
Cahill 2015 J Biol Chem	2015	Cahill TJ, Leo V, Kelly M, Stockenhuber A, Kennedy NW, Bao L, Cereghetti G, Harper AR, Czibik G, Lao C, Bellahcene M, Steeples V, Ghaffari S, Yavari A, Mayer A, Poulton J, Ferguson D, Scorrano L, Hettiarachchi NT, Peers C, Boyle J, Hill RB, Simmons A, Watkins H, Dear TN, Ashrafian H (2015) Resistance of dynamin-related protein 1 oligomers to disassembly impairs mitophagy resulting in myocardial inflammation and heart failure. J Biol Chem 290:25907-19.	LEAK OXPHOS ET	N S NS ROX	Permeabilized tissue	Mouse	Heart
Hansson 2015 Eur J Pharmacol	2015	Hansson MJ, Llwyd O, Morin D, de Paulis D, Arnoux T, Gouarné C, Koul S, Engblom H, Bordet T, Tissier R, Arheden H, Erlinge D, Halestrap AP, Berdeaux A, Pruss RM, Schaller S (2015) Differences in the profile of protection afforded by TRO40303 and mild hypothermia in models of cardiac ischemia/reperfusion injury. Eur J Pharmacol 760:7-19.	LEAK OXPHOS ET	N S NS	Permeabilized tissue	Pig	Heart
Yan 2015 BMC Cancer	2015	Yan B, Stantic M, Zobalova R, Bezawork-Geleta A, Stapelberg M, Stursa J, Prokopova K, Dong L, Neuzil J (2015) Mitochondrially targeted vitamin E succinate efficiently kills breast tumour-initiating cells in a complex II-dependent manner. BMC Cancer 15:401.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Permeabilized cells Intact cells	Human Mouse	Genital Other cell lines
Kruse 2015 Aging Cell	2015	Kruse SE, Karunadharma PP, Basisty N, Johnson R, Beyer RP, MacCoss MJ, Rabinovitch PS, Marcinek DJ (2015) Age modifies respiratory complex I and protein homeostasis in a muscle type-specific manner. Aging Cell 15:89-99.	LEAK OXPHOS ET	N S CIV NS ROX	Permeabilized tissue	Mouse	Skeletal muscle
Ping 2015 Oxid Med Cell Longev	2015	Ping Z, Zhang LF, Cui YJ, Chang YM, Jiang CW, Meng ZZ, Xu P, Liu HY, Wang DY, Cao XB (2015) The protective effects of Salidroside from exhaustive exercise-induced heart injury by enhancing the PGC-1𝛼–NRF1/NRF2 pathway and mitochondrial respiratory function in rats. Oxid Med Cell Longev Article ID 876825.	OXPHOS ET	N S CIV ROX	Permeabilized tissue	Rat	Heart
Paeaesuke 2015 Oxid Med Cell Longev	2015	Pääsuke R, Eimre M, Piirsoo A, Peet N, Laada L, Kadaja L, Roosimaa M, Pääsuke M, Märtson A, Seppet E, Paju K (2015) Proliferation of human primary myoblasts is associated with altered energy metabolism in dependence of ageing in vivo and in vitro. Oxid Med Cell Longev 8296150:10p.	OXPHOS	N S CIV ROX	Permeabilized cells	Human	Skeletal muscle
Krumschnabel 2015 Methods Mol Biol	2015	Krumschnabel G, Fontana-Ayoub M, Sumbalova Z, Heidler J, Gauper K, Fasching M, Gnaiger E (2015) Simultaneous high-resolution measurement of mitochondrial respiration and hydrogen peroxide production. Methods Mol Biol 1264:245-61.	LEAK OXPHOS ET	N S NS ROX	Isolated mitochondria	Mouse	Nervous system
Wang 2015 Nat Commun	2015	Wang Y, Oxer D, Hekimi S (2015) Mitochondrial function and lifespan of mice with controlled ubiquinone biosynthesis. Nat Commun 6:6393.	LEAK OXPHOS	N S	Isolated mitochondria	Mouse	Heart Skeletal muscle Kidney
Schoettl 2015 Mol Metab	2015	Schöttl T, Kappler L, Fromme T, Klingenspor M (2015) Limited OXPHOS capacity in white adipocytes is a hallmark of obesity in laboratory mice irrespective of the glucose tolerance status. Mol Metab 4:631-42.	LEAK ROUTINE OXPHOS ET	F N S ROX	Isolated mitochondria Intact cells	Mouse	Fat Other cell lines
Doerrier 2015 Thesis	2015	Doerrier C (2015) Estudio bioenergetica mitochondrial en la sepsis experimental y efecto protector de la Melatonina. Doctoral Thesis p154.	LEAK OXPHOS ET	N S NS	Permeabilized tissue Isolated mitochondria	Mouse	Heart Liver
Nelson 2015 Master Thesis	2015	Nelson MB (2015) The role of receptors for advanced glycation end-products (RAGE) and ceramide in cardiovascular disease. Master Thesis 1-53.	LEAK OXPHOS ET	N S NS	Permeabilized cells Permeabilized tissue	Mouse Rat	Heart Other cell lines
Canto 2015 Curr Protoc Mouse Biol	2015	Cantó C, Garcia-Roves PM (2015) High-resolution respirometry for mitochondrial characterization of ex vivo mouse tissues. Curr Protoc Mouse Biol 5:135-53.	LEAK OXPHOS ET	N S NS	Permeabilized tissue Homogenate	Mouse	Heart Skeletal muscle Nervous system Liver Fat
MiPNet12.11 MitoRespiration	2014-02-20	Flux control ratios in isolated mitochondria. OXPHOS capacity and respiratory control.		S	Isolated mitochondria	Artemia Crustaceans
Baggio 2014 Nucleic Acids Res	2014	Baggio F, Bratic A, Mourier A, Kauppila TE, Tain LS, Kukat C, Habermann B, Partridge L, Larsson NG5 (2014) Drosophila melanogaster LRPPRC2 is involved in coordination of mitochondrial translation. Nucleic Acids Res 42:13920-38.	LEAK OXPHOS ET	N S Gp CIV Other combinations	Permeabilized tissue	Drosophila Hexapods

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