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From Bioblast
Year | Reference | Coupling | Pathway | Preparation | Organism | Tissue;cell | |
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Houghton 2018 Free Radic Biol Med | 2018 | Houghton MJ, Kerimi A, Tumova S, Boyle JP, Williamson G (2018) Quercetin preserves redox status and stimulates mitochondrial function in metabolically-stressed HepG2 cells. Free Radic Biol Med 129:296-309. | LEAK ROUTINE ET | ROX | Intact cells | Human | Liver |
Haschka 2018 Mov Disord | 2018 | Haschka D, Volani C, Stefani A, Tymoszuk P, Mitterling T, Holzknecht E, Heidbreder A, Coassin S, Sumbalova Z, Seifert M, Dichtl S, Theurl I, Gnaiger E, Kronenberg F, Frauscher B, Högl B, Weiss G (2018) Association of mitochondrial iron deficiency and dysfunction with idiopathic restless legs syndrome. Mov Disord 34:114-23. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells Lymphocyte |
Ejarque 2018 Int J Obes (Lond) | 2018 | Ejarque M, Ceperuelo-Mallafré V, Serena C, Maymo-Masip E, Duran X, Díaz-Ramos A, Millan-Scheiding M, Núñez-Álvarez Y, Núñez-Roa C, Gama P, Garcia-Roves PM, Peinado MA, Gimble JM, Zorzano A, Vendrell J, Fernández-Veledo S (2018) Adipose tissue mitochondrial dysfunction in human obesity is linked to a specific DNA methylation signature in adipose-derived stem cells. Int J Obes (Lond) 43:1256-68. | LEAK ROUTINE ET | CIV ROX | Intact cells | Human | Fat |
Cronin 2018 Nature | 2018 | Cronin SJF, Seehus C, Weidinger A, Talbot S, Reissig S, Seifert M, Pierson Y, McNeill E, Longhi MS, Turnes BL, Kreslavsky T, Kogler M, Hoffmann D, Ticevic M, da Luz Scheffer D, Tortola L, Cikes D, Jais A, Rangachari M, Rao S, Paolino M, Novatchkova M, Aichinger M, Barrett L, Latremoliere A, Wirnsberger G, Lametschwandtner G, Busslinger M, Zicha S, Latini A, Robson SC, Waisman A, Andrews N, Costigan M, Channon KM, Weiss G, Kozlov AV, Tebbe M, Johnsson K, Woolf CJ, Penninger JM (2018) The metabolite BH4 controls T cell proliferation in autoimmunity and cancer. Nature 563:564-68. | ROUTINE OXPHOS ET LEAK | N S | Permeabilized cells Intact cells | Mouse | Lymphocyte |
Doucet 2018 Mol Pharmacol | 2018 | Doucet MS, Jougleux JL, Poirier SJ, Cormier M, Leger JL, Surette ME, Pichaud N, Touaibia M, Boudreau LH (2018) Identification of peracetylated quercetin as a selective 12-lipoxygenase pathway inhibitor in human platelets. Mol Pharmacol 95:139-50. | LEAK ROUTINE ET | ROX | Intact cells | Human | Platelet Blood cells |
Bombaca 2018 Free Radic Biol Med | 2018 | Bombaça ACS, Viana PG, Santos ACC, Silva TL, Rodrigues ABM, Guimarães ACR, Goulart MOF, Da Silva Júnior EN, Menna-Barreto RFS (2018) Mitochondrial disfunction and ROS production are essential for anti-Trypanosoma cruzi activity of β-lapachone-derived naphthoimidazoles. Free Radic Biol Med 130:408-18. | ROUTINE | ROX | Intact organism | Protists | |
MitoFit Open Seminar 2017-07-14 | 2017-07-14 |
Innsbruck AT, 2017 Jul 14. MitoFit Open Seminar on immune cell bioenergetics. Investigating the role of mitochondria in healthy and psychopathological aging. | LEAK ROUTINE ET | Intact cells | Human | Blood cells | |
Alves 2017 Free Radic Biol Med | 2017 | Alves de Souza CE, Alves de Souza HM, Stipp MC, Corso CR, Galindo CM, Cardoso CR, Dittrich RL, de Souza Ramos EA, Klassen G, Carlos RM, Correia Cadena SMS, Acco A (2017) Ruthenium complex exerts antineoplastic effects that are mediated by oxidative stress without inducing toxicity in Walker-256 tumor-bearing rats. Free Radic Biol Med 110:228-39. | LEAK ROUTINE | ROX | Rat | ||
Rohde 2017 Cell Death Differ | 2017 | Rohde K, Kleinesudeik L, Roesler S, Löwe O, Heidler J, Schröder K, Wittig I, Dröse S, Fulda S (2017) A Bak-dependent mitochondrial amplification step contributes to Smac mimetic/glucocorticoid-induced necroptosis. Cell Death Differ 24:83-97. | LEAK ROUTINE ET | CIV ROX | Intact cells | Mouse | Fibroblast |
Nogueira 2017 Free Radic Biol Med | 2017 | Nogueira NP, Saraiva FMS, Oliveira MP, Mendonca APM, Inacio JDF, Almeida-Amaral EE, Menna-Barreto RF, Laranja GAT, Lopes Torres EJ, Oliveira MF, Paes MC (2017) Heme modulates Trypanosoma cruzi bioenergetics inducing mitochondrial ROS production. Free Radic Biol Med 108:183-91. | LEAK ROUTINE OXPHOS ET | S | Intact organism Permeabilized cells | Protists | |
Da Silva 2017 Life Sci | 2017 | da Silva MH, Peçanha FLM, de Oliveira AM, da-Silva WS (2017) 4-Phenyl butyric acid increases particulate hexokinase activity and protects against ROS injury in L6 myotubes. Life Sci 179:98-102. | ROUTINE | Intact cells | Rat | Skeletal muscle Other cell lines | |
Rezania 2017 Thromb Res | 2017 | Rezania S, Puskarich MA, Petrusca DN, Neto-Neves EM, Rondina MT, Kline JA (2017) Platelet hyperactivation, apoptosis and hypercoagulability in patients with acute pulmonary embolism. Thromb Res 155:106-15. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells Platelet |
Rodolphi 2017 Thesis | 2017 | Rodolphi MS (2017) Efeitos da nandrolona e da ceftriaxona na homeostasia glutamatérgica: uma busca por mecanismos interativos entre astrócitos e neurônios envolvidos no comportamento agressivo. Dissertation p58. | ROUTINE OXPHOS | S CIV ROX | Homogenate | Mouse | Nervous system |
Thaher 2017 Neurochem Int | 2017 | Thaher O, Wolf C, Dey PN, Pouya A, Wüllner V, Tenzer S, Methner A (2017) The thiol switch C684 in Mitofusin-2 mediates redox-induced alterations of mitochondrial shape and respiration. Neurochem Int 117:167-73. | LEAK ROUTINE OXPHOS ET | N NS ROX | Intact cells Permeabilized cells | Mouse | Fibroblast |
Rodrigues-Silva 2017 J Neurooncol | 2017 | Rodrigues-Silva E, Siqueira-Santos ES, Ruas JS, Ignarro RS, Figueira TR, Rogério F, Castilho RF (2017) Evaluation of mitochondrial respiratory function in highly glycolytic glioma cells reveals low ADP phosphorylation in relation to oxidative capacity. 10.1007/s11060-017-2482-0 | LEAK ROUTINE OXPHOS ET | N ROX | Permeabilized cells Isolated mitochondria Intact cells | Rat | Nervous system |
Ounpuu 2017 Biochim Biophys Acta | 2017 | Ounpuu L, Klepinin A, Pook M, Teino I, Peet N, Paju K, Tepp K, Chekulayev V, Shevchuk I, Koks S, Maimets T, Kaambre T (2017) 2102Ep embryonal carcinoma cells have compromised respiration and shifted bioenergetic profile distinct from H9 human embryonic stem cells. Biochim Biophys Acta 1861:2146-54. | LEAK ROUTINE OXPHOS ET | N S NS ROX CIV | Permeabilized cells Intact cells | Human | Stem cells |
Cunha de Padua 2017 Carbohydr Polym | 2017 | Cunha de Padua MM, Suter Correia Cadena SM, de Oliveira Petkowicz CL, Martinez GR, Rodrigues Noleto G (2017) Toxicity of native and oxovanadium (IV/V) galactomannan complexes on HepG2 cells is related to impairment of mitochondrial functions. Carbohydr Polym 173:665-75. | LEAK ROUTINE ET | ROX | Human | Liver | |
Holland 2017 Placenta | 2017 | Holland OJ, Hickey AJR, Alvsaker A, Moran S, Hedges C, Chamley LW, Perkins AV (2017) Changes in mitochondrial respiration in the human placenta over gestation. Placenta 57:102-12. | LEAK ROUTINE OXPHOS | F N CIV NS ROX | Permeabilized cells Intact cells | Genital | |
Asiri 2017 Thesis | 2017 | Asiri A (2017) Effects of asiatic acid on neurite outgrowth in Neuro-2a cells. Master's Thesis p42. | LEAK ROUTINE ET | Intact cells | Mouse | Nervous system | |
Sidlauskas 2017 Neurosci Lett | 2017 | Sidlauskas K, Sidlauskiene R, Li N, Liobikas J (2017) 5-Hydroxy-1,4-naphthalenedione exerts anticancer effects on glioma cells through interaction with the mitochondrial electron transport chain. Neurosci Lett 639:207-14. | OXPHOS LEAK ROUTINE ET | N S | Intact cells Permeabilized cells | Rat | Nervous system Other cell lines |
Shimakawa 2017 Sci Rep | 2017 | Shimakawa G, Matsuda Y, Nakajima K, Tamoi M, Shigeoka S, Miyake C (2017) Diverse strategies of O2 usage for preventing photo-oxidative damage under CO2 limitation during algal photosynthesis. Sci Rep 7:41022. doi: 10.1038/srep41022 | ROUTINE | Eubacteria Plants Algae | |||
Canevarolo 2017 Thesis | 2017 | Canevarolo RR (2017) Resistência ao metotrexato está diretamente associada à concentração de glutationa em linhagens de leucemia linfoide aguda. Dissertation p159. | LEAK ROUTINE ET | Intact cells | Human | Macrophage-derived | |
Theisen 2017 Am J Med Genet A | 2017 | Theisen BE, Rumyantseva A, Cohen JS, Alcaraz WA, Shinde DN, Tang S, Srivastava S, Pevsner J, Trifunovic A, Fatemi A (2017) Deficiency of WARS2, encoding mitochondrial tryptophanyl tRNA synthetase, causes severe infantile onset leukoencephalopathy. Am J Med Genet A 173:2505-10. | LEAK ROUTINE ET | ROX | Intact cells | Human | Endothelial;epithelial;mesothelial cell Fibroblast |
Zeidler 2017 J Biol Chem | 2017 | Zeidler JD, Fernandes-Siqueira LO, Carvalho AS, Cararo-Lopes E, Dias MH, Ketzer LA, Galina A, Da Poian AT (2017) Short-term starvation is a strategy to unravel the cellular capacity of oxidizing specific exogenous/endogenous substrates in mitochondria. J Biol Chem 292:14176-87. | LEAK ROUTINE ET | F N ROX | Intact cells | Mouse | |
Tegelberg 2017 Orphanet J Rare Dis | 2017 | Tegelberg S, Tomašić N, Kallijärvi J, Purhonen J, Elmér E, Lindberg E, Nord DG, Soller M, Lesko N, Wedell A, Bruhn H, Freyer C, Stranneheim H, Wibom R, Nennesmo I, Wredenberg A, Eklund EA, Fellman V (2017) Respiratory chain complex III deficiency due to mutated BCS1L: a novel phenotype with encephalomyopathy, partially phenocopied in a Bcs1l mutant mouse model. Orphanet J Rare Dis 12:73. | LEAK ROUTINE OXPHOS ET | N NS ROX S | Permeabilized cells | Human Mouse | Blood cells Platelet |
Phillips 2017 Cancer Res | 2017 | Phillips CM, Zatarain JR, Nicholls ME, Porter C, Widen SG, Thanki K, Johnson P, Jawad MU, Moyer MP, Randall JW, Hellmich JL, Maskey M, Qiu S, Wood TG, Druzhyna N, Szczesny B, Módis K1, Szabo C, Chao C, Hellmich MR. (2017) Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis.. Cancer Res. 77(21):5741-5754. | LEAK ROUTINE ET | Intact cells | Human | Endothelial;epithelial;mesothelial cell | |
Lopez 2017 PLOS ONE | 2017 | López A, Ortiz F, Doerrier C, Venegas C, Fernández-Ortiz M, Aranda P, Díaz-Casado ME, Fernández-Gil B, Barriocanal-Casado E, Escames G, López L, Acuña-Castroviejo D (2017) Mitochondrial impairment and melatonin protection in parkinsonian mice do not depend of inducible or neuronal nitric oxide synthases. PLOS ONE 12:e0183090. | LEAK ROUTINE OXPHOS | N S NS | Isolated mitochondria | Mouse | |
Miettinen 2017 Trends Cell Biol | 2017 | Miettinen TP, Björklund M (2017) Mitochondrial function and cell size: an allometric relationship. Trends Cell Biol 27:393-402. | ROUTINE | Intact organism Intact cells | |||
Beresewicz 2017 PLoS One | 2017 | Beresewicz M, Boratynska-Jasinska A, Charzewski L, Kawalec M, Kabzinska D, Kochanski A, Krzysko KA, Zablocka B (2017) The effect of a novel c.820C>T (Arg274Trp) mutation in the mitofusin 2 gene on fibroblast metabolism and clinical manifestation in a patient. PLoS One 12:0169999. | LEAK ET ROUTINE | Intact cells | Human | Fibroblast Endothelial;epithelial;mesothelial cell | |
Jezek 2017 Biochim Biophys Acta | 2017 | Ježek J, Engstová H, Ježek P (2017) Antioxidant mechanism of mitochondria-targeted plastoquinone SkQ1 is suppressed in aglycemic HepG2 cells dependent on oxidative phosphorylation. Biochim Biophys Acta 1858:750-62. | ET ROUTINE | ROX | Intact cells | Human | Liver |
Li 2017 Oxid Med Cell Longev | 2017 | Li CJ, Chen PK, Sun LY, Pang CY (2017) Enhancement of mitochondrial transfer by antioxidants in human mesenchymal stem cells. Oxid Med Cell Longev 2017:8510805. | ET LEAK ROUTINE | ROX | Intact cells | Human | Fat |
Morrow 2017 Proc Natl Acad Sci U S A | 2017 | Morrow RM, Picard M, Derbeneva O, Leipzig J, McManus MJ, Gouspillou G, Barbat-Artigas S, Dos Santos C, Hepple RT, Murdock DG, Wallace DC (2017) Mitochondrial energy deficiency leads to hyperproliferation of skeletal muscle mitochondria and enhanced insulin sensitivity. Proc Natl Acad Sci U S A 114:2705-10. | ROUTINE OXPHOS LEAK | N NS ROX Other combinations | Permeabilized tissue | Skeletal muscle | |
Uzhachenko 2017 Aging (Albany NY) | 2017 | Uzhachenko R, Boyd K, Olivares-Villagomez D, Zhu Y, Goodwin JS, Rana T, Shanker A, Tan WJ, Bondar T, Medzhitov R, Ivanova AV (2017) Mitochondrial protein Fus1/Tusc2 in premature aging and age-related pathologies: critical roles of calcium and energy homeostasis. Aging (Albany NY) 9:627-49. | LEAK ET ROUTINE | ROX | Intact cells | Mouse | Kidney Endothelial;epithelial;mesothelial cell Fibroblast |
Seo 2017 Elife | 2017 | Seo AY, Lau PW, Feliciano D, Sengupta P, Gros MAL, Cinquin B, Larabell CA, Lippincott-Schwartz J (2017) AMPK and vacuole-associated Atg14p orchestrate μ-lipophagy for energy production and long-term survival under glucose starvation. Elife 6. pii: e21690. | ROUTINE | Saccharomyces cerevisiae | |||
Shuvo 2017 Can J Microbiol | 2017 | Shuvo SR, Kovaltchouk U, Zubaer A, Kumar A, Summers WAT, Donald LJ, Hausner G, Court DA (2017) Functional characterization of an N-terminally-truncated mitochondrial porin expressed in Neurospora crassa. Can J Microbiol 17:1-9. | ROUTINE | Isolated mitochondria | Fungi | ||
Cigliano 2017 Mol Neurobiol | 2017 | Cigliano L, Spagnuolo MS, Crescenzo R, Cancelliere R, Iannotta L, Mazzoli A, Liverini G, Iossa S (2017) Short-term fructose feeding induces inflammation and oxidative stress in the hippocampus of young and adult rats. Mol Neurobiol 55:2869-83. | ROUTINE | CIV Other combinations | Homogenate Intact cells | Rat | Nervous system Other cell lines |
Schaefer 2017 Thesis | 2017 | Schaefer P (2017) Metabolic imaging in Alzheimer´s disease using NADH autofluorescence. Dissertation p93. | LEAK ET ROUTINE | CIV ROX | Intact cells | Human | HEK Other cell lines |
Chang 2017 J Biol Chem | 2017 | Chang JS, Ha K (2017) An unexpected role for the transcriptional coactivator isoform NT-PGC-1α in the regulation of mitochondrial respiration in brown adipocytes. J Biol Chem 292:9958-66. | LEAK ET ROUTINE | ROX | Intact cells | Mouse | Fat |
Greenall 2017 Oncogenesis | 2017 | Greenall SA, Lim YC, Mitchell CB, Ensbey KS, Stringer BW, Wilding AL, O'Neill GM, McDonald KL, Gough DJ, Day BW, Johns TG (2017) Cyclin-dependent kinase 7 is a therapeutic target in high-grade glioma. Oncogenesis 6:e336. | ROUTINE | Intact cells | Human | Nervous system | |
McFarlane 2017 Am J Physiol Regul Integr Comp Physiol | 2017 | McFarlane SV, Mathers KE, Staples JF (2017) Reversible temperature-dependent differences in brown adipose tissue respiration during torpor in a mammalian hibernator. Am J Physiol Regul Integr Comp Physiol 312:R434-42. | LEAK ROUTINE OXPHOS | F N | Isolated mitochondria Intact cells | Other mammals | Fat |
Yang 2017 Cell Death Dis | 2017 | Yang N, Weinfeld M, Lemieux H, Montpetit B, Goping IS (2017) Photo-activation of the delocalized lipophilic cation D112 potentiates cancer selective ROS production and apoptosis. Cell Death Dis 8:e2587. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Intact cells | Saccharomyces cerevisiae Human | Lymphocyte |
Goncalves 2017 J Cell Commun Signal | 2017 | Gonçalves R, Zamoner A, Zanatta L, Zanatta AP, Remor AP, da Luz Scheffer D, Latini A, Silva FR (2017) 1,25(OH)2 vitamin D3 signalling on immature rat Sertoli cells: gamma-glutamyl transpeptidase and glucose metabolism. J Cell Commun Signal 11:233-43. | LEAK ROUTINE ET | ROX | Intact cells | Rat | Genital |
Saintas 2017 PLOS ONE | 2017 | Saintas E, Abrahams L, Ahmad GT, Ajakaiye AM, AlHumaidi AS, Ashmore-Harris C, Clark I, Dura UK, Fixmer CN, Ike-Morris C, Mato Prado M, Mccullough D, Mishra S, Schöler KM, Timur H, Williamson MD, Alatsatianos M, Bahsoun B, Blackburn E, Hogwood CE, Lithgow PE, Rowe M, Yiangou L, Rothweiler F, Cinatl J Jr, Zehner R, Baines AJ, Garrett MD, Gourlay CW, Griffin DK, Gullick WJ, Hargreaves E, Howard MJ, Lloyd DR, Rossman JS, Smales CM, Tsaousis AD, von der Haar T, Wass MN, Michaelis M (2017) Acquired resistance to oxaliplatin is not directly associated with increased resistance to DNA damage in SK-N-ASrOXALI4000, a newly established oxaliplatin-resistant sub-line of the neuroblastoma cell line SK-N-AS. PLOS ONE 12:e0172140. | LEAK ROUTINE ET | Intact cells | Human | Nervous system Other cell lines | |
Elmer 2017 US Patent | 2017 | Elmer E, Hansson MJ, Ehinger JK, Piel S, Moss S (2017) Succinate prodrugs for use in the treatment of lactic acidosis or drug-induced side-effects due to complex I-related impairment of mitochondrial oxidative phosphorylation. US Patent US20170100359 A1. | LEAK ROUTINE OXPHOS ET | S ROX | Intact cells | Human | Heart Blood cells Fibroblast Macrophage-derived Platelet |
Porter 2017 Adipocyte | 2017 | Porter C (2017) Quantification of UCP1 function in human brown adipose tissue. Adipocyte 6:167-74. | LEAK ROUTINE OXPHOS ET | Permeabilized tissue Isolated mitochondria Intact cells | Fat | ||
Davis 2017 Tissue Eng Part C Methods | 2017 | Davis BN, Santoso JW, Walker MJ, Cheng CS, Koves TR, Kraus WE, Truskey GA (2017) Human, tissue-engineered, skeletal muscle myobundles to measure oxygen uptake and assess mitochondrial toxicity. Tissue Eng Part C Methods 23:189-99. | LEAK ROUTINE ET | ROX | Intact cells | Human | Skeletal muscle |
Ortega 2017 Biol Reprod | 2017 | Ortega MS, Wohlgemuth S, Tribulo P, Siqueira LG, Null DJ, Cole JB, Da Silva MV, Hansen PJ (2017) A single nucleotide polymorphism in COQ9 affects mitochondrial and ovarian function and fertility in Holstein cows. Biol Reprod 96:652-63. | LEAK ROUTINE ET | ROX | Bovines | Blood cells | |
Bernardinelli 2017 PLoS One | 2017 | Bernardinelli E, Costa R, Scantamburlo G, To J, Morabito R, Nofziger C, Doerrier C, Krumschnabel G, Paulmichl M, Dossena S (2017) Mis-targeting of the mitochondrial protein LIPT2 leads to apoptotic cell death. PLoS One 12(6):e0179591. | LEAK ROUTINE ET | ROX | Intact cells | Human | Kidney |
Cunha 2017 Int J Biol Macromol | 2017 | Cunha de Padua MM, Suter Correia Cadena SM, de Oliveira Petkowicz CL, Martinez GR, Rodrigues Noleto G (2017) Galactomannan from Schizolobium amazonicum seed and its sulfated derivatives impair metabolism in HepG2 cells. Int J Biol Macromol 101:64-473. | LEAK ROUTINE ET | ROX | Intact cells | Human | Liver |
Pino 2017 Int J Obes (Lond) | 2017 | Pino MF, Divoux A, Simmonds AV, Smith SR, Sparks LM (2017) Investigating the effects of Orexin-A on thermogenesis in human deep neck brown adipose tissue. Int J Obes (Lond) 41:1646-53. | LEAK ROUTINE | Intact cells | Human | Fat | |
Friederich 2017 Hum Mol Genet | 2017 | Friederich MW, Erdogan AJ, Coughlin CR 2nd, Elos MT, Jiang H, O'Rourke CP, Lovell MA, Wartchow E, Gowan K, Chatfield KC, Chick WS, Spector EB, Van Hove JLK, Riemer J (2017) Mutations in the accessory subunit NDUFB10 result in isolated complex I deficiency and illustrate the critical role of intermembrane space import for complex I holoenzyme assembly. Hum Mol Genet 26:702-16. | ROUTINE OXPHOS ET LEAK | N S CIV NS ROX | Permeabilized cells Intact cells | Human | Fibroblast |
Kang 2017 Mol Cell | 2017 | Kang Y, Stroud DA, Baker MJ, De Souza DP, Frazier AE, Liem M, Tull D, Mathivanan S, McConville MJ, Thorburn DR, Ryan MT, Stojanovski D (2017) Sengers Syndrome-associated mitochondrial acylglycerol kinase is a subunit of the human TIM22 protein import complex. Mol Cell 67:457-70. | ROUTINE ET | Intact cells | Human | ||
Boutant 2017 EMBO J | 2017 | Boutant M, Kulkarni SS, Joffraud M, Ratajczak J, Valera-Alberni M, Combe R, Zorzano A, Cantó C (2017) Mfn2 is critical for brown adipose tissue thermogenic function. EMBO J 36:1543-58. | ROUTINE LEAK OXPHOS ET | ROX N S NS | Intact cells Homogenate Isolated mitochondria | Mouse | Fat Fibroblast |
Westerlund 2017 Pediatr Res | 2017 | Westerlund E, Marelsson SE, Ehinger JK, Sjövall F, Morota S, Åsander Frostner E, Oldfors A, Darin N, Lundgren J, Hansson MJ, Fellman V, Elmér E (2017) Oxygen consumption in platelets as an adjunct diagnostic method for pediatric mitochondrial disease. Pediatr Res 83:455-65. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Intact cells | Human | Platelet Blood cells |
Favero 2017 Thesis | 2017 | Favero BC (2017) Efeitos da leucina sobre a via da mTOR e da miostatina em cultura celular de miotúbulos. Dissertation p55. | LEAK ROUTINE ET | Mouse | Skeletal muscle | ||
Michalak 2017 Oxid Med Cell Longev | 2017 | Michalak S, Florczak-Wyspiańska J, Rybacka-Mossakowska J, Ambrosius W, Osztynowicz K, Baszczuk A, Kozubski W, Wysocka E (2017) Mitochondrial respiration in intact peripheral blood mononuclear cells and sirtuin 3 activity in patients with movement disorders. Oxid Med Cell Longev 2017:9703574. | LEAK ROUTINE ET | ROX | Intact cells | Blood cells | |
Permer 2017 Bachelor Thesis | 2017 | Permer M (2017) Respirometrische Charakterisierung kryopräservierter HEK 239T Zellen. Bachelor Thesis 1-56. | LEAK ROUTINE OXPHOS ET | F N S Gp CIV NS ROX | Permeabilized cells Intact cells | Human | Other cell lines HEK |
Xu 2017 J Hum Genet | 2017 | Xu B, Li X, Du M, Zhou C, Fang H, Lyu J, Yang Y (2017) Novel mutation of ND4 gene identified by targeted next-generation sequencing in patient with Leigh syndrome. J Hum Genet 62:291-7. | LEAK ROUTINE | Intact cells | Human | Blood cells Platelet | |
JanssenDuijghuijsen 2017 Front Physiol | 2017 | JanssenDuijghuijsen LM, Grefte S, de Boer VCJ, Zeper L, van Dartel DAM, van der Stelt I, Bekkenkamp-Grovenstein M, van Norren K, Wichers HJ, Keijer J (2017) Mitochondrial ATP depletion disrupts Caco-2 monolayer integrity and internalizes Claudin 7. Front Physiol 8:794. | LEAK ROUTINE ET | ROX | Intact cells | Human | Endothelial;epithelial;mesothelial cell Other cell lines |
Cunha-de 2017 Thesis | 2017 | Cunha-de Padua MM (2017) Mecanismos citotóxicos da galactomanana de sementes de Schizolobium amazonicum e seus complexos com oxovanádio em células de hepatocarcinoma humano (HepG2) e efeito do silenciamento da enzima glucose-6-fosfato isomerase (GPI) na sobrevivência de células de adenocarcinoma de cólon humano (LS174T). Doctoral Thesis p160. | LEAK ROUTINE OXPHOS ET | N NS ROX | Intact cells Permeabilized cells | Human | Liver Other cell lines |
Mantilla 2017 PLOS Pathog | 2017 | Mantilla BS, Marchese L, Casas-Sánchez A, Dyer NA, Ejeh N, Biran M, Bringaud F, Lehane MJ, Acosta-Serrano A, Silber AM (2017) Proline metabolism is essential for Trypanosoma brucei brucei survival in the tsetse vector. PLOS Pathog 13:e1006158. | LEAK OXPHOS ET ROUTINE | S ROX N | Permeabilized cells Intact cells | Protists | |
Bombaca 2017 Free Radic Biol Med | 2017 | Bombaça ACS, Dias FA, Ennes-Vidal V, Garcia-Gomes ADS, Sorgine MHF, d'Avila-Levy CM, Menna-Barreto RFS (2017) Hydrogen peroxide resistance in Strigomonas culicis: Effects on mitochondrial functionality and Aedes aegypti interaction. Free Radic Biol Med 113:255-66. | ROUTINE | CIV ROX | Intact cells | Protists | |
Pfeiffer 2017 Free Radic Biol Med | 2017 | Pfeiffer A, Schneider J, Bueno D, Dolga A, Voss TD, Lewerenz J, Wüllner V, Methner A (2017) Bcl-xL knockout attenuates mitochondrial respiration and causes oxidative stress that is compensated by pentose phosphate pathway activity. Free Radic Biol Med 112:350-9. | LEAK ROUTINE OXPHOS ET | N NS ROX | Permeabilized cells | Mouse | Fibroblast |
Cervoni 2017 J Exp Biol | 2017 | Cervoni MS, Cardoso-Júnior CAM, Craveiro G, Souza AO, Alberici LC, Hartfelder K (2017) Mitochondrial capacity, oxidative damage and hypoxia gene expression are associated with age-related division of labor in honey bee (Apis mellifera L.) workers. J Exp Biol 220:4035-46. | LEAK ROUTINE OXPHOS ET | N ROX | Intact cells | ||
Xiong 2017 J Am Heart Assoc | 2017 | Xiong S, Wang B, Lin S, Zhang H, Li Y, Wei X, Cui Y, Wei X, Lu Z, Gao P, Li L, Zhao Z, Liu D, Zhu Z (2017) Activation of transient receptor potential melastatin subtype 8 attenuates cold-induced hypertension through ameliorating vascular mitochondrial dysfunction. J Am Heart Assoc 6. pii: e005495. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Mouse | Endothelial;epithelial;mesothelial cell |
Ruiz 2017 Brain Pathol | 2017 | Ruiz M, Bégou M, Launay N, Ranea-Robles P, Bianchi P, López-Erauskin J, Morató L, Guilera C, Petit B, Vaurs-Barriere C, Guéret-Gonthier C, Bonnet-Dupeyron MN, Fourcade S, Auwerx J, Boespflug-Tanguy O, Pujol A (2017) Oxidative stress and mitochondrial dynamics malfunction are linked in Pelizaeus-Merzbacher disease. Brain Pathol 28:611-30. | LEAK ROUTINE ET | ROX | Intact cells | Human Mouse | Nervous system Fibroblast |
De Souza 2017 Thesis | 2017 | de Souza LF (2017) Modulação redox de peroxirredoxinas e a participação dos sistemas da GSH e da Trx na proteção/função celular. Tese (doutorado) p103. | LEAK ROUTINE ET | Intact cells | Human | Other cell lines | |
Djordjevic 2017 Neuroscience | 2017 | Djordjevic J, Thomson E, Chowdhury SR, Snow WM, Perez C, Wong TP, Fernyhough P, Albensi BC (2017) Brain region- and sex-specific alterations in mitochondrial function and NF-κB signaling in the TgCRND8 mouse model of Alzheimer's disease. Neuroscience 361:81-92. | ROUTINE OXPHOS ET | N S ROX | Isolated mitochondria | Mouse | Nervous system |
Welker 2017 Thesis | 2017 | Welker L (2017) Metabolic and morphologic shifts in Neuro2a cells cultured in galactose medium. Master's Thesis p26. | LEAK ROUTINE ET | Intact cells | Mouse | ||
Dechandt 2017 J Bioenerg Biomembr | 2017 | Dechandt CRP, Zuccolotto-Dos-Reis FH, Teodoro BG, Fernandes AMAP, Eberlin MN, Kettelhut IC, Curti C, Alberici LC (2017) Triacsin C reduces lipid droplet formation and induces mitochondrial biogenesis in primary rat hepatocytes. J Bioenerg Biomembr 49:399-411. | LEAK ROUTINE ET | F N ROX | Permeabilized cells Intact cells | Rat | Liver |
Singhal 2017 Mol Biol Cell | 2017 | Singhal RK, Kruse C, Heidler J, Strecker V, Zwicker K, Düsterwald L, Westermann B, Herrmann JM, Wittig I, Rapaport D (2017) Coi1 is a novel assembly factor of the yeast complex III-complex IV supercomplex. Mol Biol Cell 28:2609-22. | ROUTINE ET | Isolated mitochondria | Saccharomyces cerevisiae | ||
Jang 2017 Clin Toxicol (Phila) | 2017 | Jang DH, Kelly M, Hardy K, Lambert DS, Shofer FS, Eckmann DM (2017) A preliminary study in the alterations of mitochondrial respiration in patients with carbon monoxide poisoning measured in blood cells. Clin Toxicol (Phila) 55:579-84. | LEAK ROUTINE OXPHOS ET | F S CIV NS ROX | Intact cells | Blood cells | |
Tueller 2017 Biochem Biophys Res Commun | 2017 | Tueller DJ, Harley JS, Hancock CR (2017) Effects of curcumin and ursolic acid on the mitochondrial coupling efficiency and hydrogen peroxide emission of intact skeletal myoblasts. Biochem Biophys Res Commun 492:368-72. | LEAK ROUTINE OXPHOS | F N NS ROX | Permeabilized cells Intact cells | Skeletal muscle | |
Zhou 2017 Oxid Med Cell Longev | 2017 | Zhou H, Nie K, Qiu R, Xiong J, Shao X, Wang B, Shen L, Lyu J, Fang H (2017) Generation and bioenergetic profiles of cybrids with east Asian mtDNA haplogroups. Oxid Med Cell Longev 2017:1062314. | LEAK ROUTINE | Intact cells | Human | ||
Frawley 2017 Chem Res Toxicol | 2017 | Frawley KL, Cronican AA, Pearce LL, Peterson J (2017) Sulfide toxicity and its modulation by nitric oxide in bovine pulmonary artery endothelial cells. Chem Res Toxicol 30:2100-9. | ROUTINE | Intact cells | Bovines | Endothelial;epithelial;mesothelial cell | |
Profilo 2017 Biochim Biophys Acta | 2017 | Profilo E, Peña-Altamira LE, Corricelli M, Castegna A, Danese A, Agrimi G, Petralla S, Giannuzzi G, Porcelli V, Sbano L, Viscomi C, Massenzio F, Palmieri EM, Giorgi C, Fiermonte G, Virgili M, Palmieri L, Zeviani M, Pinton P, Monti B, Palmieri F, Lasorsa FM (2017) Down-regulation of the mitochondrial aspartate-glutamate carrier isoform 1 AGC1 inhibits proliferation and N-acetylaspartate synthesis in Neuro2A cells. Biochim Biophys Acta 1863:1422-35. | LEAK ET ROUTINE | ROX | Intact cells | Mouse | Nervous system Other cell lines Neuroblastoma |
De Carvalho 2017 Sci Rep | 2017 | de Carvalho AETS, Bassaneze V, Forni MF, Keusseyan AA, Kowaltowski AJ, Krieger JE (2017) Early postnatal cardiomyocyte proliferation requires high oxidative energy metabolism. Sci Rep 7:15434. | ROUTINE | Intact cells | Rat | Heart | |
Wu 2017 Sci Rep | 2017 | Wu LH, Chang SC, Fu TC, Huang CH, Wang JS (2017) High-intensity interval training improves mitochondrial function and suppresses thrombin generation in platelets undergoing hypoxic stress. Sci Rep 7:4191. | LEAK OXPHOS ET ROUTINE | N NS ROX CIV | Permeabilized cells Intact cells | Human | Blood cells Platelet |
Lang 2017 Aging (Albany NY) | 2017 | Lang A, Anand R, Altinoluk-Hambüchen S, Ezzahoini H, Stefanski A, Iram A, Bergmann L, Urbach J, Böhler P, Hänsel J, Franke M, Stühler K, Krutmann J, Scheller J, Stork B, Reichert AS, Piekorz RP (2017) SIRT4 interacts with OPA1 and regulates mitochondrial quality control and mitophagy. Aging (Albany NY) 9:2163-89. | LEAK ET ROUTINE | ROX | Intact cells | Human | Kidney HEK |
Scrima 2017 PLOS ONE | 2017 | Scrima R, Menga M, Pacelli C, Agriesti F, Cela O, Piccoli C, Cotoia A, De Gregorio A, Gefter JV, Cinnella G, Capitanio N (2017) Para-hydroxyphenylpyruvate inhibits the pro-inflammatory stimulation of macrophage preventing LPS-mediated nitro-oxidative unbalance and immunometabolic shift. PLOS ONE 12:e0188683. | LEAK ROUTINE ET | ROX | Intact cells | Human Mouse | Endothelial;epithelial;mesothelial cell Blood cells Fibroblast Macrophage-derived |
Zholobenko 2017 PLOS ONE | 2017 | Zholobenko AV, Mouithys-Mickalad A, Dostal Z, Serteyn D, Modriansky M (2017) On the causes and consequences of the uncoupler-like effects of quercetin and dehydrosilybin in H9c2 cells. PLOS ONE 12:e0185691. | LEAK OXPHOS ET ROUTINE | F N S NS ROX | Permeabilized cells Intact cells | Rat | Heart |
Schaefer 2017 Neurophotonics | 2017 | Schaefer PM, Hilpert D, Niederschweiberer M, Neuhauser L, Kalinina S, Calzia E, Rueck A, von Einem B, von Arnim CAF (2017) Mitochondrial matrix pH as a decisive factor in neurometabolic imaging. Neurophotonics 4:045004. | ROUTINE ET | CIV ROX | Kidney HEK | ||
Comelli 2017 J Bioenerg Biomembr | 2017 | Comelli M, Pretis I, Buso A, Mavelli I (2017) Mitochondrial energy metabolism and signalling in human glioblastoma cell lines with different PTEN gene status. J Bioenerg Biomembr 50:33-52. | LEAK ROUTINE OXPHOS ET | N Gp CIV NS ROX | Intact cells Permeabilized cells | Human | Nervous system |
Jang 2017 Biol Open | 2017 | Jang DH, Seeger SC, Grady ME, Shofer FC, Eckmann DM (2017) Mitochondrial dynamics and respiration within cells with increased open pore cytoskeletal meshes. Biol Open 6:1831-9. | LEAK ROUTINE ET | N S CIV NS ROX | Permeabilized cells Intact cells | Human | Endothelial;epithelial;mesothelial cell Fibroblast |
Ma 2017 Int J Cancer | 2017 | Ma L, Fu Q, Xu B, Zhou H, Gao J, Shao X, Xiong J, Gu Q, Wen S, Li F, Shen L, Chen G, Fang H, Lyu J (2017) Breast cancer-associated mitochondrial DNA haplogroup promotes neoplastic growth via ROS-mediated AKT activation. Int J Cancer 142:1786-96. | LEAK ROUTINE ET | Intact cells | Human | ||
Ortega-Dominguez 2017 Food Chem Toxicol | 2017 | Ortega-Domínguez B, Aparicio-Trejo OE, García-Arroyo FE, León-Contreras JC, Tapia E, Molina-Jijón E, Hernández-Pando R, Sánchez-Lozada LG, Barrera-Oviedo D, Pedraza-Chaverri J (2017) Curcumin prevents cisplatin-induced renal alterations in mitochondrial bioenergetics and dynamic. Food Chem Toxicol 107:373-85. | LEAK ROUTINE OXPHOS | N NS | Isolated mitochondria | ||
Wang 2017 J Am Heart Assoc | 2017 | Wang B, Xiong S, Lin S, Xia W, Li Q, Zhao Z, Wei X, Lu Z, Wei X, Gao P, Liu D, Zhu Z (2017) Enhanced mitochondrial transient receptor potential channel, canonical type 3-mediated calcium handling in the vasculature from hypertensive rats. J Am Heart Assoc 6. pii: e005812. | ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells | Rat | Endothelial;epithelial;mesothelial cell |
Garcia-Neto 2017 PLOS ONE | 2017 | Garcia-Neto W, Cabrera-Orefice A, Uribe-Carvajal S, Kowaltowski AJ, Luévano-Martínez LA (2017) High osmolarity environments activate the mitochondrial alternative oxidase in Debaryomyces Hansenii. PLOS ONE 12:e0169621. https://doi.org/10.1371/journal.pone.0169621 | ROUTINE | CIV ROX | Isolated mitochondria Intact cells | Fungi | |
Blecha 2017 Free Radic Biol Med | 2017 | Blecha J, Novais SM, Rohlenova K, Novotna E, Lettlova S, Schmitt S, Zischka H, Neuzil J, Rohlena J (2017) Antioxidant defense in quiescent cells determines selectivity of electron transport chain inhibition-induced cell death. Free Radic Biol Med 112:253-66. | ROUTINE OXPHOS | S | Intact cells | Endothelial;epithelial;mesothelial cell | |
Beresewicz 2017 PLOS ONE | 2017 | Beręsewicz M, Boratyńska-Jasińska A, Charzewski Ł, Kawalec M, Kabzińska D, Kochański A, Krzyśko KA, Zabłocka B (2017) The effect of a novel c.820C>T (Arg274Trp) mutation in the mitofusin 2 gene on fibroblast metabolism and clinical manifestation in a patient. PLOS ONE 12:e0169999. | LEAK ET ROUTINE | Intact cells | Human | Endothelial;epithelial;mesothelial cell Fibroblast | |
Radenkovic 2017 Biochem Pharmacol | 2017 | Radenkovic F, Holland OJ, Vanderlelie JJ, Perkins AV (2017) Selective inhibition of endogenous antioxidants with Auranofin causes mitochondrial oxidative stress which can be countered by selenium supplementation. Biochem Pharmacol 146:42-52. | ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells | Human | Other cell lines |
Bansal 2017 Environ Health Perspect | 2017 | Bansal A, Rashid C, Xin F, Li C, Polyak E, Duemler A, van der Meer T, Stefaniak M, Wajid S, Doliba N, Bartolomei MS, Simmons RA (2017) Sex- and dose-specific effects of maternal bisphenol A exposure on pancreatic islets of first- and second-generation adult mice offspring. Environ Health Perspect 125:097022. | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Islet cell;pancreas;thymus |
MiPNet21.14 Reference sample HRR | 2016-10-19 | Development of a reference sample for HRR. | LEAK ROUTINE OXPHOS ET | F N S Gp CIV NS Other combinations ROX | Intact cells Permeabilized cells | Human | HEK |
MiPNet21.12 Comparison mt respiration media | 2016-10-18 | O2k-MultiSensor: Mitochondrial respiration media for HRR and simultaneous O2k-Fluorometry. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Intact cells Permeabilized cells | Human | HEK |
MiPNet08.09 CellRespiration | 2016-08-11 | High-resolution respirometry and coupling-control protocol with living cells: ROUTINE, LEAK, ET-pathway, ROX. | LEAK ROUTINE ET | Intact cells | Human | Blood cells Lymphocyte | |
MiPNet10.04 CellRespiration | 2016-08-08 | An experiment with high-resolution respirometry: coupling control in cell respiration. | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Blood cells |
Jang 2016 J Intensive Care Med | 2016 | Jang DH, Greenwood JC, Spyres MB, Eckmann D (2016) Measurement of mitochondrial respiration and motility in acute care: sepsis, trauma, and poisoning. J Intensive Care Med 32:86-94. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells Lymphocyte |
Zhunussova 2016 PLOS ONE | 2016 | Zhunussova A, Vitol EA, Polyak B, Tuleukhanov S, Brooks AD, Sensenig R, Friedman G, Orynbayeva Z (2016) Mitochondria-mediated anticancer effects of non-thermal atmospheric plasma. PLOS ONE 11:e0156818. | LEAK ROUTINE ET | Intact cells | Human | Genital Other cell lines | |
Zelenka 2016 Oxid Med Cell Longev | 2016 | Zelenka J, Dvořák A, Alán L, Zadinová M, Haluzík M, Vítek L (2016) Hyperbilirubinemia protects against aging-associated inflammation and metabolic deterioration. Oxid Med Cell Longev ID 6190609:10p. | ROUTINE | Intact cells Isolated mitochondria | Rat | Liver Kidney Fibroblast | |
Camacho-Pereira 2016 Cell Metab | 2016 | Camacho-Pereira J, Tarragó MG, Chini CC, Nin V, Escande C, Warner GM, Puranik AS, Schoon RA, Reid JM, Galina A, Chini EN (2016) CD38 dictates age-related NAD decline and mitochondrial dysfunction through an SIRT3-dependent mechanism. Cell Metab 23:1127-39. | LEAK ROUTINE OXPHOS ET | S ROX | Isolated mitochondria Intact cells | Human Mouse | Liver Lung;gill Other cell lines |
Kawalec 2016 Praca doktorska | 2016 | Kawalec MM (2016) Badanie komórkowych skutków mutacji w genie mitofuzyny 2. Próba zaproponowania testu patogenności mutacji. Praca doktorska p86. | LEAK ROUTINE ET | Intact cells | Mouse | Fibroblast | |
Barth 2016 Thesis | 2016 | Barth C (2016) Effekte einer intermittierenden Hyperoxie auf die mitochondriale Atmung in Alveolarmakrophagen. Dissertation p69. | LEAK ROUTINE OXPHOS | N S CIV NS ROX | Permeabilized cells Intact cells | Mouse | Lung;gill Macrophage-derived |
Oliveira 2016 PLOS ONE | 2016 | Oliveira MP, Correa Soares JB, Oliveira MF (2016) Sexual preferences in nutrient utilization regulate oxygen consumption and reactive oxygen species generation in Schistosoma mansoni: potential implications for parasite redox biology. PLOS ONE 11:e0158429. | LEAK ROUTINE | F ROX | Intact organism | Other invertebrates | |
Vevera 2016 Physiol Res | 2016 | Vevera J, Fišar Z, Nekovářová T, Vrablík M, Zlatohlávek L, Hroudová J, Singh N, Raboch J, Valeš K (2016) Statin-induced changes in mitochondrial respiration in blood platelets in rats and human with dyslipidemia. Physiol Res 65:777-88. | LEAK ROUTINE OXPHOS ET | N S NS Other combinations ROX | Intact cells Permeabilized cells | Human Rat | Blood cells Platelet |
Boeck 2016 Mitochondrion | 2016 | Boeck C, Koenig AM, Schury K, Geiger ML, Karabatsiakis A, Wilker S, Waller C, Gündel H, Fegert JM, Calzia E, Kolassa IT (2016) Inflammation in adult women with a history of child maltreatment: The involvement of mitochondrial alterations and oxidative stress. Mitochondrion 30:197-207. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells Lymphocyte |
Davuluri 2016 Proc Natl Acad Sci U S A | 2016 | Davuluri G, Song P, Liu Z, Wald D, Sakaguchi TF, Green MR, Devireddy L (2016) Inactivation of 3-hydroxybutyrate dehydrogenase 2 delays zebrafish erythroid maturation by conferring premature mitophagy. Proc Natl Acad Sci U S A 113:E1460-9. | LEAK ROUTINE ET | Intact cells | Zebrafish | Blood cells | |
Schinagl 2016 PLoS One | 2016 | Schinagl CW, Vrabl P, Burgstaller W (2016) Adapting high-resolution respirometry to glucose-limited steady state mycelium of the filamentous fungus Penicillium ochrochloron: method development and standardisation. PLoS One 11:e0146878. | ROUTINE ET | Intact cells | Fungi | ||
Puskarich 2016 J Crit Care | 2016 | Puskarich MA, Kline JA, Watts JA, Shirey K, Hosler J, Jones AE (2016) Early alterations in platelet mitochondrial function are associated with survival and organ failure in patients with septic shock. J Crit Care 31:63-7. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells Platelet |
Cacabelos 2016 Neurobiol Dis | 2016 | Cacabelos D, Ayala V, Granado-Serrano AB, Jové M, Torres P, Boada J, Cabré R, Ramírez-Núñez O, Gonzalo H, Soler-Cantero A, Serrano JC, Bellmunt MJ, Romero MP, Motilva MJ, Nonaka T, Hasegawa M, Ferrer I, Pamplona R, Portero-Otín M (2016) Interplay between TDP-43 and docosahexaenoic acid-related processes in amyotrophic lateral sclerosis. Neurobiol Dis 88:148-60. | ROUTINE | Intact cells | Rat | Nervous system | |
Raturi 2016 J Cell Biol | 2016 | Raturi A, Gutiérrez T, Ortiz-Sandoval C, Ruangkittisakul A, Herrera-Cruz MS, Rockley JP, Gesson K, Ourdev D, Lou PH, Lucchinetti E, Tahbaz N, Zaugg M, Baksh S, Ballanyi K, Simmen T (2016) TMX1 determines cancer cell metabolism as a thiol-based modulator of ER-mitochondria Ca2+ flux. J Cell Biol 214:433-44. | LEAK ET ROUTINE | Permeabilized cells Intact cells | Mouse Human | HeLa Other cell lines | |
Fonseca-Berzal 2016 Parasitology | 2016 | Fonseca-Berzal C, DA Silva CF, Menna-Barreto RF, Batista MM, Escario JA, Arán VJ, Gómez-Barrio A, Soeiro Mde N (2016) Biological approaches to characterize the mode of action of two 5-nitroindazolinone prototypes on Trypanosoma cruzi bloodstream trypomastigotes. Parasitology 143:1469-78. | ROUTINE | ROX | Intact organism | Protists | |
Birkenmeier 2016 Int J Cancer | 2016 | Birkenmeier Katrin, Droese Stefan, Wittig Ilka, Winkelmann Ria, Kaefer Viktoria, Doering Claudia, Hartmann Sylvia, Wenz Tina, Reichert Andreas S, Brandt Ulrich, Hansmann Martin‐Leo (2016) Hodgkin and Reed-Sternberg cells of classical Hodgkin lymphoma are highly dependent on oxidative phosphorylation. Int J Cancer 138:2231-46. | LEAK ROUTINE ET | ROX | Intact cells | Human | Other cell lines HeLa Macrophage-derived |
Jang 2016 Clin Toxicol (Phila) | 2016 | Jang DH, Shofer FS, Weiss SL, Becker LB (2016) Impairment of mitochondrial respiration following ex vivo cyanide exposure in peripheral blood mononuclear cells. Clin Toxicol (Phila) 54:303-7. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells Lymphocyte |
Schaefer 2016 PLOS ONE | 2016 | Schaefer PM, von Einem B, Walther P, Calzia E, von Arnim CA (2016) Metabolic characterization of intact cells reveals intracellular amyloid beta but not its precursor protein to reduce mitochondrial respiration. PLOS ONE 11:e0168157. | LEAK ROUTINE ET | CIV ROX | Intact cells | Human Mouse | Nervous system HEK |
Sengupta 2016 Free Radic Biol Med | 2016 | Sengupta S, Yang G, O'Donnell JC, Hinson MD, McCormack SE, Falk MJ, La P, Robinson MB, Williams ML, Yohannes MT, Polyak E, Nakamaru-Ogiso E, Dennery PA (2016) The circadian gene Rev-erbα improves cellular bioenergetics and provides preconditioning for protection against oxidative stress. Free Radic Biol Med 93:177-89. | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Lung;gill Fibroblast |
Salvi 2016 Oxid Med Cell Longev | 2016 | Salvi A, Patki G, Khan E, Asghar M, Salim S (2016) Protective effect of tempol on buthionine sulfoximine (BSO)-induced mitochondrial impairment in hippocampal derived HT22 cells. Oxid Med Cell Longev 2016:5059043. | ROUTINE | Intact cells | Mouse | Nervous system Other cell lines | |
Reynolds 2016 Am J Physiol Endocrinol Metab | 2016 | Reynolds MS, Hancock CR, Ray JD, Kener KB, Draney C, Garland K, Hardman J, Bikman BT, Tessem JS (2016) β-cell deletion of Nr4a1 and Nr4a3 nuclear receptors impedes mitochondrial respiration and insulin secretion. Am J Physiol Endocrinol Metab 311:E186-201. | LEAK ROUTINE OXPHOS ET | N S ROX | Permeabilized cells Intact cells | Rat | Islet cell;pancreas;thymus |
Holandino 2016 Bioelectrochemistry | 2016 | Holandino C, Teixeira CA, de Oliveira FA, Barbosa GM, Siqueira CM, Messeder DJ, de Aguiar FS, da Veiga VF, Girard-Dias W, Miranda K, Galina A, Capella MA, Morales MM (2016) Direct electric current treatment modifies mitochondrial function and lipid body content in the A549 cancer cell line. Bioelectrochemistry 111:83-92. | LEAK ROUTINE ET | ROX | Intact cells | Human | Lung;gill Other cell lines |
Xiong 2016 Hypertension | 2016 | Xiong S, Wang P, Ma L, Gao P, Gong L, Li L, Li Q, Sun F, Zhou X, He H, Chen J, Yan Z, Liu D, Zhu Z (2016) Ameliorating endothelial mitochondrial dysfunction restores coronary function via transient receptor potential vanilloid 1-mediated protein kinase A/uncoupling protein 2 pathway. Hypertension 67:451-60. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Intact cells Permeabilized cells | Human | Endothelial;epithelial;mesothelial cell Other cell lines |
Scrima 2016 Biochim Biophys Acta | 2016 | Scrima R, Cela O, Merla G, Augello B, Rubino R, Quarato G, Fugetto S, Menga M, Fuhr L, Relógio A, Piccoli C, Mazzoccoli G, Capitanio N (2016) Clock-genes and mitochondrial respiratory activity: Evidence of a reciprocal interplay. Biochim Biophys Acta 1857:1344-51. | LEAK ROUTINE ET | ROX | Intact cells | Human | Liver Endothelial;epithelial;mesothelial cell Other cell lines Fibroblast |
Sheremet 2016 Biochemistry (Moscow) | 2016 | Sheremet NL, Nevinitsyna TA, Zhorzholadze NV, Ronzina IA, Itkis YS, Krylova TD, Tsygankova PG, Malakhova VA, Zakharova EY, Tokarchuk AV, Panteleeva AA, Karger EM, Lyamzaev KG, Avetisov SE (2016) Previously unclassified mutation of mtDNA m.3472T>C: evidence of pathogenicity in Leber’s hereditary optic neuropathy. Biochemistry (Moscow) BM16-078. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | Endothelial;epithelial;mesothelial cell Fibroblast Platelet |
Gdynia 2016 Nat Commun | 2016 | Gdynia G, Sauer SW, Kopitz J, Fuchs D, Duglova K, Ruppert T, Miller M, Pahl J, Cerwenka A, Enders M, Mairbäurl H, Kamiński MM, Penzel R, Zhang C, Fuller JC, Wade RC, Benner A, Chang-Claude J, Brenner H, Hoffmeister M, Zentgraf H, Schirmacher P, Roth W (2016) The HMGB1 protein induces a metabolic type of tumour cell death by blocking aerobic respiration. Nat Commun 7:10764. | ROUTINE | ROX | Permeabilized cells | Human | Endothelial;epithelial;mesothelial cell Other cell lines |
Sanchez-Calvo 2016 PLOS ONE | 2016 | Sánchez-Calvo B, Cassina A, Rios N, Peluffo G, Boggia J, Radi R, Rubbo H, Trostchansky A (2016) Nitro-arachidonic acid prevents Angiotensin II-induced mitochondrial dysfunction in a cell line of kidney proximal tubular cells. PLOS ONE 11:e0150459. | LEAK ROUTINE ET | ROX | Intact cells | Human | Kidney Other cell lines |
Lesage 2016 Am J Hum Genet | 2016 | Lesage S, Drouet V, Majounie E, Deramecourt V, Jacoupy M, Nicolas A, Cormier-Dequaire F, Hassoun SM, Pujol C, Ciura S, Erpapazoglou Z, Usenko T, Maurage CA, Sahbatou M, Liebau S, Ding J, Bilgic B, Emre M, Erginel-Unaltuna N, Guven G, Tison F, Tranchant C, Vidailhet M, Corvol JC, Krack P, Leutenegger AL, Nalls MA, Hernandez DG, Heutink P, Gibbs JR, Hardy J, Wood NW, Gasser T, Durr A, Deleuze JF, Tazir M, Destée A, Lohmann E, Kabashi E, Singleton A, Corti O, Brice A (2016) Loss of VPS13C function in autosomal-recessive parkinsonism causes mitochondrial dysfunction and increases PINK1/Parkin-Dependent Mitophagy. Am J Hum Genet 98:500-13. | LEAK ROUTINE ET | ROX | Intact cells | Other mammals | Kidney Other cell lines |
Bynum 2016 Transfusion | 2016 | Bynum JA, Adam Meledeo M, Getz TM, Rodriguez AC, Aden JK, Cap AP, Pidcoke HF (2016) Bioenergetic profiling of platelet mitochondria during storage: 4°C storage extends platelet mitochondrial function and viability. Transfusion 56 Suppl 1:S76-84. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells Platelet |
Cheng 2016 Nat Immunol | 2016 | Cheng SC, Scicluna BP, Arts RJ, Gresnigt MS, Lachmandas E, Giamarellos-Bourboulis EJ, Kox M, Manjeri GR, Wagenaars JA, Cremer OL, Leentjens J, van der Meer AJ, van de Veerdonk FL, Bonten MJ, Schultz MJ, Willems PH, Pickkers P, Joosten LA, van der Poll T, Netea MG (2016) Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis. Nat Immunol 17:406-13. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells Lymphocyte |
Ehinger 2016 Mov Disord | 2016 | Ehinger JK, Morota S, Hansson MJ, Gesine P, Elmér E (2016) Mitochondrial respiratory function in peripheral blood cells from Huntington’s disease patients. Mov Disord doi:10.1002/mdc3.12308. | LEAK ROUTINE OXPHOS ET | N S CIV NS Other combinations ROX | Permeabilized cells Intact cells | Human | Blood cells Lymphocyte Platelet |
Lores-Arnaiz 2016 Neurochem Res | 2016 | Lores-Arnaiz S, Lombardi P, Karadayian AG, Orgambide F, Cicerchia D, Bustamante J (2016) Brain cortex mitochondrial bioenergetics in synaptosomes and non-synaptic mitochondria during aging. Neurochem Res 41:353-63. | LEAK ROUTINE OXPHOS ET | N S | Isolated mitochondria Intact cells | Mouse | Nervous system |
Castellano-Gonzalez 2016 Oncotarget | 2016 | Castellano-González G, Pichaud N, Ballard JW, Bessede A, Marcal H, Guillemin GJ (2016) Epigallocatechin-3-gallate induces oxidative phosphorylation by activating cytochrome c oxidase in human cultured neurons and astrocytes. Oncotarget 7:7426-40 | LEAK ROUTINE ET | ROX | Intact cells | Human | Nervous system |
Silva 2016 Thesis | 2016 | Silva Luana Caroline Schüeler da (2016) Fucoxantina inibe a oxidação de LDL e ativação de macrófagos in vitro. PhD Thesis:93 pp. | LEAK ROUTINE ET | ROX | Intact cells | Human | |
Siewiera 2016 Life Sci | 2016 | Siewiera K, Kassassir H, Talar M, Wieteska L, Watala C (2016) Higher mitochondrial potential and elevated mitochondrial respiration are associated with excessive activation of blood platelets in diabetic rats. Life Sci 148:293-304. | LEAK ROUTINE ET | ROX | Intact cells | Rat | Blood cells Platelet |
Rohlenova 2016 Antioxid Redox Signal | 2016 | Rohlenova K, Sachaphibulkij K, Stursa J, Bezawork-Geleta A, Blecha J, Endaya B, Werner L, Cerny J, Zobalova R, Goodwin J, Spacek T, Alisadeh E, Yan B, Nguyen M, Vondrusova M, Sobol M, Jezek P, Hozak P, Truksa J, Rohlena J, Dong L, Neuzil J (2016) Selective disruption of respiratory supercomplexes as a new strategy to suppress Her2high breast cancer. Antioxid Redox Signal 26:84-103. | LEAK ROUTINE ET | N S Other combinations | Permeabilized cells Homogenate | Human Mouse | Liver Genital Other cell lines |
Cacabelos 2016 Acta Neuropathol Commun | 2016 | Cacabelos D, Ramírez-Núñez O, Granado-Serrano AB, Torres P, Ayala V, Moiseeva V, Povedano M, Ferrer I, Pamplona R, Portero-Otin M, Boada J (2016) Early and gender-specific differences in spinal cord mitochondrial function and oxidative stress markers in a mouse model of ALS. Acta Neuropathol Commun 4:3. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized tissue Intact cells | Mouse | Nervous system Other cell lines |
Barison 2016 J Bioenerg Biomembr | 2016 | Barisón MJ, Damasceno FS, Mantilla BS, Silber AM (2016) The active transport of histidine and its role in ATP production in Trypanosoma cruzi. J Bioenerg Biomembr 48:437-49. | LEAK ROUTINE ET | Intact cells | Protists | ||
Svenkrtova 2016 Biogerontology | 2016 | Svenkrtova A, Belicova L, Volejnikova A, Sigler K, Jazwinski SM, Pichova A (2016) Stratification of yeast cells during chronological aging by size points to the role of trehalose in cell vitality. Biogerontology 17:395-408. | ROUTINE | CIV ROX | Intact cells | Saccharomyces cerevisiae | |
Hancock 2016 Amino Acids | 2016 | Hancock CN, Liu W, Alvord WG, Phang JM (2016) Co-regulation of mitochondrial respiration by proline dehydrogenase/oxidase and succinate. Amino Acids 48:859-72. | LEAK ROUTINE ET | S Other combinations ROX | Isolated mitochondria Oxidase;biochemical oxidation Intact cells | Mouse | Liver |
Gerber 2016 J Med Genet | 2016 | Gerber S, Ding MG, Gérard X, Zwicker K, Zanlonghi X, Rio M, Serre V, Hanein S, Munnich A, Rotig A, Bianchi L, Amati-Bonneau P, Elpeleg O, Kaplan J, Brandt U, Rozet JM (2016) Compound heterozygosity for severe and hypomorphic NDUFS2 mutations cause non-syndromic LHON-like optic neuropathy. J Med Genet 54:346-56. | LEAK ROUTINE ET | ROX | Intact cells | Human | Endothelial;epithelial;mesothelial cell Fibroblast |
Strecker 2016 Biochim Biophys Acta | 2016 | Strecker V, Kadeer Z, Heidler J, Cruciat CM, Angerer H, Giese H, Pfeiffer K, Stuart RA, Wittig I (2016) Supercomplex-associated Cox26 protein binds to cytochrome c oxidase. Biochim Biophys Acta 1863:1643-52. | ROUTINE ET | ROX | Intact cells | Saccharomyces cerevisiae | |
Chakraborty 2016 Pancreatology | 2016 | Chakraborty M, Hickey AJ, Petrov MS, Macdonald JR, Thompson N, Newby L, Sim D, Windsor JA, Phillips AR (2016) Mitochondrial dysfunction in peripheral blood mononuclear cells in early experimental and clinical acute pancreatitis. Pancreatology 16:739-47. | LEAK OXPHOS ROUTINE ET | N Gp CIV NS ROX S | Permeabilized cells | Human Rat | Blood cells |
Kang 2016 Elife | 2016 | Kang Y, Baker MJ, Liem M, Louber J, McKenzie M, Atukorala I, Ang CS, Keerthikumar S, Mathivanan S, Stojanovski D (2016) Tim29 is a novel subunit of the human TIM22 translocase and is involved in complex assembly and stability. Elife 5:e17463. | ROUTINE ET | ROX | Intact cells | Human | |
Berschneider 2016 Thesis | 2016 | Berschneider K (2016) Connecting the functions of the proteasome and mitochondria in the lung. Dissertation p161. | LEAK ROUTINE ET | ROX | Permeabilized cells | Mouse | Lung;gill |
Davuluri 2016 J Physiol | 2016 | Davuluri G, Allawy A, Thapaliya S, Rennison JH, Singh D, Kumar A, Sandlers Y, Van Wagoner DR, Flask CA, Hoppel C, Kasumov T, Dasarathy S (2016) Hyperammonaemia-induced skeletal muscle mitochondrial dysfunction results in cataplerosis and oxidative stress. J Physiol 594:7341-60. | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Skeletal muscle Other cell lines |
Dutra 2016 Acta Trop | 2016 | Dutra FL, Oliveira MM, Santos RS, Silva WS, Alviano DS, Vieira DP, Lopes AH (2016) Effects of linalool and eugenol on the survival of Leishmania (L.) infantum chagasi within macrophages. Acta Trop 164:69-76. | ROUTINE | ROX | Intact organism Intact cells | Protists | |
Yao 2016 Biochem Biophys Res Commun | 2016 | Yao K, Zhang WW, Yao L, Yang S, Nie W, Huang F (2016) Carvedilol promotes mitochondrial biogenesis by regulating the PGC-1/TFAM pathway in human umbilical vein endothelial cells (HUVECs). Biochem Biophys Res Commun 470:961-6. | ROUTINE | Intact cells | Human | Endothelial;epithelial;mesothelial cell HUVEC | |
Alvarez-Mora 2016 Mol Neurobiol | 2016 | Alvarez-Mora MI, Rodriguez-Revenga L, Madrigal I, Guitart-Mampel M, Garrabou G, Milà M (2016) Impaired mitochondrial function and dynamics in the pathogenesis of FXTAS. Mol Neurobiol 54:6896-902. | ROUTINE | N S NS | Intact cells | Human | Fibroblast |
Ferguson 2016 J Bioenerg Biomembr | 2016 | Ferguson MA, Sutton RM, Karlsson M, Sjövall F, Becker LB, Berg RA, Margulies SS, Kilbaugh TJ (2016) Increased platelet mitochondrial respiration after cardiac arrest and resuscitation as a potential peripheral biosignature of cerebral bioenergetic dysfunction. J Bioenerg Biomembr 48:269-79. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Homogenate Intact cells | Pig | Nervous system Platelet |
Anand 2016 PLOS ONE | 2016 | Anand R, Strecker V, Urbach J, Wittig I, Reichert AS (2016) Mic13 is essential for formation of crista junctions in mammalian cells. PLOS ONE 11:e0160258. | LEAK ROUTINE OXPHOS ET | N CIV NS Other combinations ROX | Permeabilized cells Intact cells | HEK | |
Maarman 2016 J Appl Physiol (1985) | 2016 | Maarman GJ, Andrew BM, Blackhurst DM, Ojuka EO (2016) Melatonin protects against uric acid-induced mitochondrial dysfunction, oxidative stress, and triglyceride accumulation in C2C12 myotubes. J Appl Physiol (1985) 122:1003-10. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Intact cells | Mouse | Skeletal muscle |
Mesquita 2016 Thesis | 2016 | Mesquita Rodrigues C (2016) Efeito da depleção de ferro sobre Leishmania (Viannia) braziliensisuma análise ultraestrutural, proteômica e interação com matrizes de colágeno sintéticas. Doctoral Dissertation p210. | ROUTINE | ROX | Intact cells | Protists | |
Wos 2016 Arch Biochem Biophys | 2016 | Woś M, Szczepanowska J, Pikuła S, Tylki-Szymańska A, Zabłocki K, Bandorowicz-Pikuła J (2016) Mitochondrial dysfunction in fibroblasts derived from patients with Niemann-Pick type C disease. Arch Biochem Biophys 593:50-9. | LEAK ROUTINE ET | Intact cells | Human | Endothelial;epithelial;mesothelial cell Fibroblast | |
Chabot 2016 J Fish Biol | 2016 | Chabot D, McKenzie DJ, Craig JF (2016) Metabolic rate in fishes: definitions, methods and significance for conservation physiology. https://doi.org/10.1111/jfb.12873. | ROUTINE | Fishes | |||
Lukasiak 2016 Eur J Pharmacol | 2016 | Łukasiak A, Skup A, Chlopicki S, Łomnicka M, Kaczara P, Proniewski B, Szewczyk A, Wrzosek A (2016) SERCA, complex I of the respiratory chain and ATP-synthase inhibition are involved in pleiotropic effects of NS1619 on endothelial cells. Eur J Pharmacol 786:137-47. | ROUTINE ET | Other combinations | Intact cells | Human | Other cell lines Endothelial;epithelial;mesothelial cell |
Safiedeen 2016 Antioxid Redox Signal | 2016 | Safiedeen Z, Rodríguez-Gómez I, Vergori L, Soleti R, Vaithilingam D, Douma I, Agouni A, Leiber D, Dubois S, Simard G, Zibara K, Andriantsitohaina R, Martínez MC (2016) Temporal cross talk between endoplasmic reticulum and mitochondria regulates oxidative stress and mediates microparticle-induced endothelial dysfunction. Antioxid Redox Signal 26:15-27. | LEAK ET ROUTINE | ROX | Intact cells | Human | Endothelial;epithelial;mesothelial cell |
Liu 2016 Apoptosis | 2016 | Liu X, Gao RW, Li M, Si CF, He YP, Wang M, Yang Y, Zheng QY, Wang CY (2016) The ROS derived mitochondrial respiration not from NADPH oxidase plays key role in Celastrol against angiotensin II-mediated HepG2 cell proliferation. Apoptosis 21:1315-26. | ROUTINE | Intact cells | Human | Liver Other cell lines | |
Schiffer 2016 Am J Physiol Cell Physiol | 2016 | Schiffer TA, Peleli M, Sundqvist ML, Ekblom B, Lundberg JO, Weitzberg E, Larsen FJ (2016) Control of human energy expenditure by cytochrome c oxidase subunit IV-2. Am J Physiol Cell Physiol 311:C452-61. | LEAK OXPHOS ET ROUTINE | N NS | Permeabilized cells Isolated mitochondria Intact cells | Human | Skeletal muscle HEK |
Shao 2016 Cell Res | 2016 | Shao LW, Niu R, Liu Y (2016) Neuropeptide signals cell non-autonomous mitochondrial unfolded protein response. Cell Res 26:1182-96. | ROUTINE | Intact organism | Caenorhabditis elegans | ||
Giraldos Jimenez 2016 Thesis | 2016 | Giraldos Jiménez D (2016) Oxidative phosphorylation system’s role in adipogenic differentiation. Thesis p25. | LEAK ROUTINE | ROX | |||
Larsen 2016 FASEB J | 2016 | Larsen FJ, Schiffer TA, Ørtenblad N, Zinner C, Morales-Alamo D, Willis SJ, Calbet JA, Holmberg HC, Boushel R (2016) High-intensity sprint training inhibits mitochondrial respiration through aconitase inactivation. FASEB J 30:417-27. | LEAK ROUTINE OXPHOS | N NS | Permeabilized cells Isolated mitochondria Intact cells | Human | Skeletal muscle |
Brandt 2016 Chem Biol Interact | 2016 | Brandt AP, Gozzi GJ, Pires Ado R, Martinez GR, Dos Santos Canuto AV, Echevarria A, Di Pietro A, Cadena SM (2016) Impairment of oxidative phosphorylation increases the toxicity of SYD-1 on hepatocarcinoma cells (HepG2). Chem Biol Interact 256:154-60. | LEAK ROUTINE ET | ROX | Intact cells | Human | Liver Other cell lines |
Tsai 2016 Sci Rep | 2016 | Tsai HH, Chang SC, Chou CH, Weng TP, Hsu CC, Wang JS (2016) Exercise training alleviates hypoxia-induced mitochondrial dysfunction in the lymphocytes of sedentary males. Sci Rep 6:35170. | LEAK ROUTINE OXPHOS ET | F N S NS Other combinations ROX | Permeabilized cells Intact cells | Human | Lymphocyte Blood cells |
Peruzzo 2016 Cell Cycle | 2016 | Peruzzo P, Comelli M, Di Giorgio E, Franforte E, Mavelli I, Brancolini C (2016) Transformation by different oncogenes relies on specific metabolic adaptations. Cell Cycle 15:2656-68. | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Fibroblast |
Watala 2016 Int J Pharm | 2016 | Watala C, Karolczak K, Kassassir H, Siewiera K, Maczynska K, Pieniazek A, Labieniec-Watala M (2016) How do the full-generation poly(amido)amine (PAMAM) dendrimers activate blood platelets? Platelet membrane zeta potential and other membrane-associated phenomena. Int J Pharm 500:379-89. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells Platelet |
McFarlane 2016 Thesis | 2016 | McFarlane SV (2016) Temperature-dependent alterations of brown adipose tissue metabolism during hibernation in the thirteen-lined ground squirrel, Ictidomys tridecemlineatus. Dissertation p74. | LEAK ROUTINE OXPHOS ET | F N | Isolated mitochondria Intact cells | Other mammals | Fat |
Drehmer 2016 Stem Cell Res | 2016 | Drehmer DL, de Aguiar AM, Brandt AP, Petiz L, Cadena SM, Rebelatto CK, Brofman PR, Filipak Neto F, Dallagiovanna B, Abud AP (2016) Metabolic switches during the first steps of adipogenic stem cells differentiation. Stem Cell Res 17:413-421. | LEAK ROUTINE ET | ROX | Intact cells | Human | Fat Stem cells |
Macheiner 2016 Sci Rep | 2016 | Macheiner T, Fengler VH, Agreiter M, Eisenberg T, Madeo F, Kolb D, Huppertz B, Ackbar R, Sargsyan K (2016) Magnetomitotransfer: An efficient way for direct mitochondria transfer into cultured human cells. Sci Rep 6:35571. | LEAK ROUTINE ET | ROX | Human | Fibroblast Lung;gill | |
Stier 2016 Methods Ecol Evol | 2016 | Stier A, Romestaing C, Schull Q, Lefol E, Robin JP, Roussel D, Bize P (2016) How to measure mitochondrial function in birds using red blood cells: a case study in the king penguin and perspectives in ecology and evolution. Methods Ecol Evol doi:10.1111/2041-210X.12724. | LEAK ROUTINE OXPHOS ET | N S ROX | Permeabilized tissue Intact cells | Birds | Skeletal muscle Blood cells |
Frey 2016 Biochim Biophys Acta | 2016 | Frey S, Geffroy G, Desquiret-Dumas V, Gueguen N, Bris C, Belal S, Amati-Bonneau P, Chevrollier A, Barth M, Henrion D, Lenaers G, Bonneau D, Reynier P, Procaccio V (2016) The addition of ketone bodies alleviates mitochondrial dysfunction by restoring complex I assembly in a MELAS cellular model. Biochim Biophys Acta 1863:284-91. | ROUTINE LEAK ET | N S NS | Permeabilized cells Intact cells | Human | Nervous system |
Bueno 2016 Thesis | 2016 | Bueno e Silva MM (2016) Alterações mitocondriais e reprogramação metabólica em células de glioblastoma após tratamento com temozolomida. Dissertation p71. | LEAK ROUTINE ET | Intact cells | Human | Nervous system Other cell lines | |
Nauta 2016 Thesis | 2016 | Nauta TD (2016) HIF-2α regulates in vitro neovascularization during hypoxia. Doctoral Dissertation p206. | LEAK ROUTINE ET | ROX | Intact cells | Human | Endothelial;epithelial;mesothelial cell |
Chubanov 2016 Elife | 2016 | Chubanov V, Ferioli S, Wisnowsky A, Simmons DG, Leitzinger C, Einer C, Jonas W, Shymkiv Y, Bartsch H, Braun A, Akdogan B, Mittermeier L, Sytik L, Torben F, Jurinovic V, van der Vorst EP, Weber C, Yildirim ÖA, Sotlar K, Schürmann A, Zierler S, Zischka H, Ryazanov AG, Gudermann T (2016) Epithelial magnesium transport by TRPM6 is essential for prenatal development and adult survival. Elife 5. pii: e20914. | ROUTINE ET | ROX | Intact cells | Human | Fibroblast Other cell lines |
Bastow 2016 J Cell Sci | 2016 | Bastow EL, Peswani AR, Tarrant DS, Pentland DR, Chen X, Morgan A, Staniforth GL, Tullet JM, Rowe ML, Howard MJ, Tuite MF, Gourlay CW (2016) New links between SOD1 and metabolic dysfunction from a yeast model of amyotrophic lateral sclerosis. J Cell Sci 129:4118-29. | LEAK ROUTINE ET | ROX | Intact cells | Saccharomyces cerevisiae | |
Moll 2016 bioRxiv | 2016 | Moll CWI, Lindtner RA, Vogel GF, Brunner M, Gutleben K, Blauth M, Krumschnabel G, Ebner HL (2016) Bone marrow mesenchymal stem cells from osteoporotic patients do not show altered mitochondrial energetics or ultrastructure. bioRxiv doi.org/10.1101/046300. | LEAK ROUTINE OXPHOS ET | N S ROX | Intact cells Permeabilized cells | Human | Stem cells |
Torres 2016 Redox Biol | 2016 | Torres S, Matías N, Baulies A, Nuñez S, Alarcon-Vila C, Martinez L, Nuño N, Fernandez A, Caballeria J, Levade T, Gonzalez-Franquesa A, Garcia-Rovés P, Balboa E, Zanlungo S, Fabrías G, Casas J, Enrich C, Garcia-Ruiz C, Fernández-Checa JC (2016) Mitochondrial GSH replenishment as a potential therapeutic approach for Niemann Pick type C disease. Redox Biol 11:60-72. | LEAK ROUTINE OXPHOS ET | N S ROX | Homogenate Intact cells | Human Mouse | Nervous system Liver Endothelial;epithelial;mesothelial cell Fibroblast |
Heimer 2016 Am J Hum Genet | 2016 | Heimer G, Kerätär JM, Riley LG, Balasubramaniam S, Eyal E, Pietikäinen LP, Hiltunen JK, Marek-Yagel D, Hamada J, Gregory A, Rogers C, Hogarth P, Nance MA, Shalva N, Veber A, Tzadok M, Nissenkorn A, Tonduti D, Renaldo F, Kraoua I, Panteghini C, Valletta L, Garavaglia B, Cowley MJ, Gayevskiy V, Roscioli T, Silberstein JM, Hoffmann C, Raas-Rothschild A, Tiranti V, Anikster Y, Christodoulou J, Kastaniotis AJ, Ben-Zeev B, Hayflick SJ (2016) MECR mutations cause childhood-onset dystonia and optic atrophy, a mitochondrial fatty acid synthesis disorder. Am J Hum Genet 99:1229-44. | LEAK ROUTINE ET | ROX | Intact cells | Human | Fibroblast |
Alonso-Vale 2015 FASEB J | 2015 | Alonso-Vale MI, Cruz M, Bolsoni-Lopes A, de Sá R, Bresciani Martins de Andrade P (2015) Palmitoleic acid (C16:1n7) treatment enhances fatty acid oxidation and oxygen consumption in white adipocytes. FASEB J 29:884.25. | ROUTINE | Intact cells | Mouse | Fat | |
Park 2015 Proc Natl Acad Sci USA | 2015 | Park JH, Kang HJ, Lee YK, Kang H, Kim J, Chung JH, Chang JS, McPherron AC, Lee SB (2015) Inactivation of EWS reduces PGC-1α protein stability and mitochondrial homeostasis. Proc Natl Acad Sci USA 112:6074-9. | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Fat |
Sjoevall 2015 US Patent | 2015 | Sjövall F, Ehinger J, Hansson M, Elmer E, Batcheller DG (2018) Mitochondrial toxicity test. US Patent US20150253306 A1. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Intact cells Permeabilized cells | Human | Blood cells Macrophage-derived Platelet |
Smolkova 2015 Int J Biochem Cell Biol | 2015 | Smolková K, Dvořák A, Zelenka J, Vítek L, Ježek P (2015) Reductive carboxylation and 2-hydroxyglutarate formation by wild-type IDH2 in breast carcinoma cells. Int J Biochem Cell Biol 65:125-33. | LEAK ROUTINE ET | ROX | Intact cells | Human | Endothelial;epithelial;mesothelial cell Other cell lines |
Neves 2015 Elife | 2015 | Neves A, Busso C, Gönczy P (2015) Cellular hallmarks reveal restricted aerobic metabolism at thermal limits. Elife 4:e04810. | ROUTINE | Intact organism | Caenorhabditis elegans | ||
Pasdar 2015 PLoS One | 2015 | Pasdar EA, Smits M, Stapelberg M, Bajzikova M, Stantic M, Goodwin J, Yan B, Stursa J, Kovarova J, Sachaphibulkij K, Bezawork-Geleta A, Sobol M, Filimonenko A, Tomasetti M, Zobalova R, Hozak P, Dong LF, Neuzil J (2015) Characterisation of mesothelioma-initiating cells and their susceptibility to anti-cancer agents. PLoS One 10:e0119549. | LEAK ROUTINE OXPHOS ET | N S NS | Permeabilized cells Intact cells | Human Mouse | Endothelial;epithelial;mesothelial cell Other cell lines |
Madsen 2015 Nat Commun | 2015 | Madsen CT, Sylvestersen KB, Young C, Larsen SC, Poulsen JW, Andersen MA, Palmqvist EA, Hey-Mogensen M, Jensen PB, Treebak JT, Lisby M, Nielsen ML (2015) Biotin starvation causes mitochondrial protein hyperacetylation and partial rescue by the SIRT3-like deacetylase Hst4p. Nat Commun 6:7726. | ROUTINE ET | Intact cells | Saccharomyces cerevisiae | ||
Ehinger 2015 J Neurol | 2015 | Ehinger JK, Morota S, Hansson MJ, Paul G, Elmér E (2015) Mitochondrial dysfunction in blood cells from amyotrophic lateral sclerosis patients. J Neurol 262:1493-503. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Intact cells | Human | Blood cells Lymphocyte Platelet |
Cagnone 2015 Methods Mol Biol | 2015 | Cagnone G, Vaghjiani V, Lee W, Sun C, Johnson J, Yeung KY, St John JC (2015) Analysis of the mitochondrial DNA and its replicative capacity in induced pluripotent stem cells. Methods Mol Biol 1357:231-67. | LEAK ROUTINE ET | ROX | Intact cells | Human | Stem cells |
Dueregger 2015 PLoS One | 2015 | Dueregger A, Schöpf B, Eder T, Höfer J, Gnaiger E, Aufinger A, Kenner L, Perktold B, Ramoner R, Klocker H, Eder IE (2015) Differential utilization of dietary fatty acids in benign and malignant cells of the prostate. PLoS One 10(8):e0135704. | LEAK ROUTINE OXPHOS ET | F N NS ROX | Permeabilized cells Permeabilized tissue | Human | Genital Other cell lines |
Yan 2015 BMC Cancer | 2015 | Yan B, Stantic M, Zobalova R, Bezawork-Geleta A, Stapelberg M, Stursa J, Prokopova K, Dong L, Neuzil J (2015) Mitochondrially targeted vitamin E succinate efficiently kills breast tumour-initiating cells in a complex II-dependent manner. BMC Cancer 15:401. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human Mouse | Genital Other cell lines |
Lourenco 2015 Front Aging Neurosci | 2015 | Lourenço CF, Ledo A, Dias C, Barbosa RM, Laranjinha J (2015) Neurovascular and neurometabolic derailment in aging and Alzheimer's disease. Front Aging Neurosci 7:103. | ROUTINE ET | ROX | Intact cells | Mouse | Nervous system |
Li 2015 Sci Rep | 2015 | Li P, Wang B, Sun F, Li Y, Li Q, Lang H, Zhao Z, Gao P, Zhao Y, Shang Q, Liu D, Zhu Z (2015) Mitochondrial respiratory dysfunctions of blood mononuclear cells link with cardiac disturbance in patients with early-stage heart failure. Sci Rep 5:10229. | LEAK ROUTINE OXPHOS ET | N S NS | Intact cells | Human | Blood cells Lymphocyte |
Mallick 2015 Cell Calcium | 2015 | Mallick RL, Kumari S, Singh N, Sonkar VK, Dash D (2015) Prion protein fragment (106-126) induces prothrombotic state by raising platelet intracellular calcium and microparticle release. Cell Calcium 57:300-11. | ROUTINE | ROX | Intact cells | Human | Blood cells Platelet |
Zhunussova 2015 Am J Cancer Res | 2015 | Zhunussova A, Sen B, Friedman L, Tuleukhanov S, Brooks AD, Sensenig R, Orynbayeva Z (2015) Tumor microenvironment promotes dicarboxylic acid carrier-mediated transport of succinate to fuel prostate cancer mitochondria. Am J Cancer Res 5:1665-79. | ROUTINE ET | S | Permeabilized cells Intact cells | Human Rat | Endothelial;epithelial;mesothelial cell Genital Other cell lines |
Zelenka 2015 Oxid Med Cell Longev | 2015 | Zelenka J, Dvořák A, Alán L (2015) L-lactate protects skin fibroblasts against aging-associated mitochondrial dysfunction via mitohormesis. Oxid Med Cell Longev 2015:351698. | LEAK ROUTINE ET | N S | Isolated mitochondria Intact cells | Rat | Liver Endothelial;epithelial;mesothelial cell Fibroblast |
Orynbayeva 2015 Nanomedicine (Lond) | 2015 | Orynbayeva Z, Sensenig R, Polyak B (2015) Metabolic and structural integrity of magnetic nanoparticle-loaded primary endothelial cells for targeted cell therapy. Nanomedicine (Lond) 10:1555-68. | LEAK ROUTINE ET | ROX | Intact cells | Rat | Endothelial;epithelial;mesothelial cell |
Ma 2015 Int J Biol Sci | 2015 | Ma W, Jing L, Valladares A, Mehta SL, Wang Z, Li PA, Bang JJ (2015) Silver nanoparticle exposure induced mitochondrial stress, caspase-3 activation and cell death: amelioration by sodium selenite. Int J Biol Sci 11:860-7. | ROUTINE | Intact cells | Mouse | Nervous system Other cell lines | |
Duskova 2015 Mol Microbiol | 2015 | Dušková M, Ferreira C, Lucas C, Sychrová H (2015) Two glycerol uptake systems contribute to the high osmotolerance of Zygosaccharomyces rouxii. Mol Microbiol 97:541-59. | ROUTINE | Intact cells | Fungi | ||
Gupta 2015 PLoS Genet | 2015 | Gupta S, Radhakrishnan A, Raharja-Liu P, Lin G, Steinmetz LM, Gagneur J, Sinha H (2015) Temporal expression profiling identifies pathways mediating effect of causal variant on phenotype. PLoS Genet 11:e1005195. | ROUTINE | Intact cells | Fungi | ||
Kelly 2015 Biotechnol J | 2015 | Kelly PS, Breen L, Gallagher C, Kelly S, Henry M, Lao NT, Meleady P, O'Gorman D, Clynes M, Barron N (2015) Re-programming CHO cell metabolism using miR-23 tips the balance towards a highly productive phenotype. Biotechnol J 10:1029-40. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Intact cells Permeabilized cells | CHO | |
Khera 2015 Placenta | 2015 | Khera A, Dong LF, Holland OJ, Vanderlelie J, Pasdar EA, Neuzil J, Perkins AV (2015) Selenium supplementation induces mitochondrial biogenesis in trophoblasts. Placenta 36:863-9. | LEAK ROUTINE OXPHOS ET | N S CIV | Permeabilized cells Intact cells | Human | Genital Other cell lines |
Kilbaugh 2015 Exp Neurol | 2015 | Kilbaugh TJ, Karlsson M, Byro M, Bebee A, Ralston J, Sullivan S, Duhaime AC, Hansson MJ, Elmér E, Margulies SS (2015) Mitochondrial bioenergetic alterations after focal traumatic brain injury in the immature brain. Exp Neurol 271:136-144. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized tissue Homogenate | Pig | Nervous system |
Grimm 2015 Exp Gerontol | 2015 | Grimm C, Osiewacz HD (2015) Manganese rescues adverse effects on lifespan and development in Podospora anserina challenged by excess hydrogen peroxide. Exp Gerontol 63:8-17. | ROUTINE | CIV ROX | Isolated mitochondria Intact cells | Fungi | |
Torelli 2015 Free Radic Biol Med | 2015 | Torelli NQ, Ferreira-Júnior JR, Kowaltowski AJ, da Cunha FM (2015) RTG1- and RTG2-dependent retrograde signaling controls mitochondrial activity and stress resistance in Saccharomyces cerevisiae. Free Radic Biol Med 81C:30-7. | LEAK ROUTINE OXPHOS ET | CIV ROX | Isolated mitochondria Intact cells | Saccharomyces cerevisiae | |
Schoettl 2015 Endocrinology | 2015 | Schöttl T, Kappler L, Braun K, Fromme T, Klingenspor M (2015) Limited mitochondrial capacity of visceral versus subcutaneous white adipocytes in male C57BL/6N mice. Endocrinology 156:923-33. | LEAK ROUTINE OXPHOS ET | N S ROX | Permeabilized cells Isolated mitochondria Intact cells | Mouse | Fat |
Coupling-control protocol | 2015 | Gnaiger E (2015) From PCP to CCP. Mitochondr Physiol Network 2015-01-11. | LEAK ROUTINE OXPHOS ET | ||||
Tan 2015 Cell Metab | 2015 | Tan AS, Baty JW, Dong L, Bezawork-Geleta A, Endaya B, Goodwin J, Bajzikova M, Kovarova J, Peterka M, Yan B, Pesdar EA, Sobol M, Filimonenko A, Stuart S, Vondrusova M, Kluckova K, Sachaphibulkij K, Rohlena J, Hozak P, Truksa J, Eccles D, Haupt LM, Griffiths LR, Neuzil J, Berridge MV (2015) Mitochondrial genome acquisition restores respiratory function and tumorigenic potential of cancer cells without mitochondrial DNA. Cell Metab 21:81-94. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Isolated mitochondria Intact cells | Human Mouse | Endothelial;epithelial;mesothelial cell Genital Other cell lines |
Blatzer 2015 Antioxid Redox Signal | 2015 | Blatzer M, Jukic E, Posch W, Schöpf B, Binder U, Steger M, Blum G, Hackl H, Gnaiger E, Lass-Flörl C, Wilflingseder D (2015) Amphotericin B resistance in Aspergillus terreus is overpowered by co-application of pro-oxidants. Antioxid Redox Signal 23:1424-38. https://doi.org/10.1089/ars.2014.6220 | ROUTINE | ROX | Intact cells | Fungi | |
Ruiz-Perez 2015 J Biol Chem | 2015 | Ruiz-Pérez MV, Medina MÁ, Urdiales JL, Keinänen TA, Sánchez-Jiménez F (2015) Polyamine metabolism is sensitive to glycolysis inhibition in human neuroblastoma cells. J Biol Chem 290:6106-19. | LEAK ROUTINE ET | ROX | Intact cells | Human | Nervous system Other cell lines Neuroblastoma |
Truksa 2015 Antioxid Redox Signal | 2015 | Truksa J, Dong L, Rohlena J, Stursa J, Vondrusova M, Goodwin J, Nguyen M, Kluckova K, Rychtarcikova Z, Lettlova S, Spacilova J, Stapelberg M, Zoratti M, Neuzil J (2015) Mitochondrially targeted vitamin E succinate modulates expression of mitochondrial DNA transcripts and mitochondrial biogenesis. Antioxid Redox Signal 22:883-900. | ROUTINE | S | Intact cells | Human Mouse | Genital Other cell lines |
Bernhardt 2015 Sci Rep | 2015 | Bernhardt D, Müller M, Reichert AS, Osiewacz HD (2015) Simultaneous impairment of mitochondrial fission and fusion reduces mitophagy and shortens replicative lifespan. Sci Rep 5:7885. | ROUTINE ET | ROX | Intact cells | Saccharomyces cerevisiae | |
Hecker 2015 Methods Mol Biol | 2015 | Hecker M, Sommer N, Mayer K (2015) Assessment of short- and medium-chain fatty acids on mitochondrial function in severe Inflammation. Methods Mol Biol 1265:389-96. | LEAK ROUTINE ET | ROX | Intact cells | Human | Endothelial;epithelial;mesothelial cell |
Kuznetsov 2015 Biochim Biophys Acta | 2015 | Kuznetsov AV, Javadov S, Sickinger S, Frotschnig S, Grimm M (2014) H9c2 and HL-1 cells demonstrate distinct features of energy metabolism, mitochondrial function and sensitivity to hypoxia-reoxygenation. Biochim Biophys Acta 1853:276-84. | ROUTINE ET | Intact cells | Rat | Heart Other cell lines | |
Jeger 2015 BioMed Res Internat | 2015 | Jeger V, Brandt S, Porta F, Jakob SM, Takala J, Djafarzadeh S (2015) Dose response of Endotoxin on hepatocyte and muscle mitochondrial respiration in vitro. BioMed Res Internat Article ID 353074:1-13. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Isolated mitochondria Intact cells | Human | Skeletal muscle Liver Other cell lines |
Negmadjanov 2015 PLOS ONE | 2015 | Negmadjanov U, Godic Z, Rizvi F, Emelyanova L, Ross G, Richards J, Holmuhamedov EL, Jahangir A (2015) TGF-β1-mediated differentiation of fibroblasts is associated with increased mitochondrial content and cellular respiration. PLOS ONE 10:e0123046. doi: 10.1371/journal.pone.0123046. | LEAK ROUTINE ET | ROX | Mouse | Fibroblast | |
Luevano-Martinez 2015 Biochim Biophys Acta | 2015 | Luévano-Martínez LA, Forni MF, Dos Santos VT, Souza-Pinto NC, Kowaltowski AJ (2015) Cardiolipin is a key determinant for mtDNA stability and segregation during mitochondrial stress. Biochim Biophys Acta 1847:587-98. | ROUTINE ET | ROX | Intact cells | Saccharomyces cerevisiae Fungi | |
Aroor 2015 Diabetes | 2015 | Aroor AR, Habibi J, Ford DA, Nistala R, Lastra G, Manrique C, Dunham MM, Ford KD, Thyfault JP, Parks EJ, Sowers JR, Rector RS (2015) Dipeptidyl peptidase-4 inhibition ameliorates western diet-induced hepatic steatosis and insulin resistance through hepatic lipid remodeling and modulation of hepatic mitochondrial function. Diabetes 64:1988-2001. | LEAK ROUTINE OXPHOS ET | F N S NS | Isolated mitochondria | Mouse | Liver |
Rodrigues 2015 J Cell Biochem | 2015 | Rodrigues MF, Carvalho É, Pezzuto P, Rumjanek FD, Amoêdo ND (2015) Reciprocal modulation of histone deacetylase inhibitors sodium butyrate and trichostatin a on the energy metabolism of breast cancer cells. Int J Biochem Cell Biol 116:797-808. | LEAK ROUTINE OXPHOS ET | ROX | Intact cells | Human | Endothelial;epithelial;mesothelial cell Other cell lines |
Hendricks 2015 Thesis | 2015 | Hendricks EW (2015) The impact of aging and estrogen therapy on synaptic mitochondrial bioenergetics in an Alzheimer's mouse model. Master Thesis 1-67. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Isolated mitochondria Intact cells | Mouse | Nervous system |
Keane 2015 Clin Sci (Lond) | 2015 | Keane KN, Calton EK, Cruzat VF, Soares MJ, Newsholme P (2015) The impact of cryopreservation on human peripheral blood leukocyte bioenergetics. Clin Sci (Lond) 128:723–33. | ROUTINE ET | Intact cells | Human | Blood cells | |
Venter 2015 J Clin Cell Immunol | 2015 | Venter G, Wijers M, Oerlemans FTJJ, Manjeri G, Fransen JAM, Wieringa B (2015) Glycolytic metabolism is differentially coupled to proliferative potential and morphodynamic capacity in RAW 264.7 and Mafb/C-Maf deficient macrophage lineages. J Clin Cell Immunol 6:1-11. | LEAK ROUTINE ET | ROX | Mouse | Blood cells Macrophage-derived | |
Adlimoghaddam 2015 J Exp Biol | 2015 | Adlimoghaddam A, Boeckstaens M, Marini AM, Treberg JR, Brassinga AK, Weihrauch D (2015) Ammonia excretion in Caenorhabditis elegans: mechanism and evidence of ammonia transport of the Rhesus protein CeRhr-1. J Exp Biol 218:675-83. | ROUTINE | Intact organism | Caenorhabditis elegans | ||
Van Rahden 2015 Am J Hum Genet | 2015 | van Rahden VA, Fernandez-Vizarra E, Alawi M, Brand K, Fellmann F, Horn D, Zeviani M, Kutsche K (2015) Mutations in NDUFB11, encoding a complex I component of the mitochondrial respiratory chain, cause microphthalmia with linear skin defects syndrome. Am J Hum Genet 96:640-50. | LEAK ROUTINE ET | Intact cells | Human | HeLa | |
Lim 2015 Am J Cancer Res | 2015 | Lim SC, Carey KT, McKenzie M (2015) Anti-cancer analogues ME-143 and ME-344 exert toxicity by directly inhibiting mitochondrial NADH: ubiquinone oxidoreductase (Complex I). Am J Cancer Res 5:689-701. | LEAK ROUTINE OXPHOS | N S | Permeabilized cells Isolated mitochondria Intact cells | Human | Kidney Other cell lines HEK HeLa Fibroblast |
Seillier 2015 EMBO Mol Med | 2015 | Seillier M, Pouyet L, N'Guessan P, Nollet M, Capo F, Guillaumond F, Peyta L, Dumas JF, Varrault A, Bertrand G, Bonnafous S, Tran A, Meur G, Marchetti P, Ravier MA, Dalle S, Gual P, Muller D, Rutter GA, Servais S, Iovanna JL, Carrier A (2015) Defects in mitophagy promote redox-driven metabolic syndrome in the absence of TP53INP1. EMBO Mol Med 7:802-18. | LEAK ROUTINE OXPHOS ET | F CIV NS ROX | Permeabilized cells Intact cells | Human Mouse | Fibroblast |
Grefte 2015 Biochim Biophys Acta | 2015 | Grefte S, Wagenaars JA, Jansen R, Willems PH, Koopman WJ (2015) Rotenone inhibits primary murine myotube formation via Raf-1 and ROCK2. Biochim Biophys Acta 1853:1606-14. | ROUTINE | Intact cells | Mouse | Skeletal muscle Other cell lines | |
Makrecka-Kuka 2015 Biomolecules | 2015 | Makrecka-Kuka M, Krumschnabel G, Gnaiger E (2015) High-resolution respirometry for simultaneous measurement of oxygen and hydrogen peroxide fluxes in permeabilized cells, tissue homogenate and isolated mitochondria. https://doi.org/10.3390/biom5031319 | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Homogenate Isolated mitochondria Intact cells | Human Mouse | Heart Nervous system HEK |
Lages 2015 PeerJ | 2015 | Lages YM, Nascimento JM, Lemos GA, Galina A, Castilho LR, Rehen SK (2015) Low oxygen alters mitochondrial function and response to oxidative stress in human neural progenitor cells. PeerJ 3:e1486. | LEAK ROUTINE ET | ROX | Intact cells | Human | Stem cells |
Plecita-Hlavata 2015 J Bioenerg Biomembr | 2015 | Plecitá-Hlavatá L, Ježek J, Ježek P (2015) Aglycemia keeps mitochondrial oxidative phosphorylation under hypoxic conditions in HepG2 cells. J Bioenerg Biomembr 47(6):467-76. | LEAK ROUTINE ET | Intact cells | Human | Liver | |
Schirris 2015 Cell Metab | 2015 | Schirris TJ, Renkema GH, Ritschel T, Voermans NC, Bilos A, van Engelen BG, Brandt U, Koopman WJ, Beyrath JD, Rodenburg RJ, Willems PH, Smeitink JA, Russel FG (2015) Statin-induced myopathy is associated with mitochondrial complex III inhibition. Cell Metab 22:399-407. | ROUTINE OXPHOS ET | N S Gp CIV NS ROX | Permeabilized cells | Human Mouse | Skeletal muscle Other cell lines |
Lisak 2015 Cell Death Differ | 2015 | Lisak D, Schacht T, Gawlitza A, Albrecht P, Aktas O, Koop B, Gliem M, Hofstetter HH, Zanger K, Bultynck G, Parys JB, De Smedt H, Kindler T, Adams-Quack P, Hahn M, Waisman A, Reed JC, Hövelmeyer N, Methner A (2015) BAX inhibitor-1 is a Ca2+ channel critically important for immune cell function and survival. Cell Death Differ 23:358-68. | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Blood cells Lymphocyte |
Schoeckel 2015 Cancer Metab | 2015 | Schöckel L, Glasauer A, Basit F, Bitschar K, Truong H, Erdmann G, Algire C, Hägebarth A, Willems PH, Kopitz C, Koopman WJ, Héroult M (2015) Targeting mitochondrial complex I using BAY 87-2243 reduces melanoma tumor growth. Cancer Metab 3:11. | ROUTINE | ROX | Intact cells | Human Mouse | Endothelial;epithelial;mesothelial cell Other cell lines |
Falabella 2015 Oxid Med Cell Longev | 2015 | Falabella M, Forte E, Magnifico MC, Santini P, Arese M, Giuffrè A, Radić K, Chessa L, Coarelli G, Buscarinu MC, Mechelli R, Salvetti M, Sarti P (2015) Evidence for detrimental cross interactions between reactive oxygen and nitrogen species in Leber’s hereditary optic neuropathy cells. Oxid Med Cell Longev 3187560. | ROUTINE | ROX | Intact cells | Human | Blood cells Lymphocyte |
Martos 2015 Plant Physiol Biochem | 2015 | Martos GG, Terán Mdel M, Díaz Ricci JC (2015) The defence elicitor AsES causes a rapid and transient membrane depolarization, a triphasic oxidative burst and the accumulation of nitric oxide. Plant Physiol Biochem 97:443-50. | ROUTINE | Intact cells | Plants | ||
Victorino 2015 Tumour Biol | 2015 | Victorino VJ, Barroso WA, Assunção AK, Cury V, Jeremias IC, Petroni R, Chausse B, Ariga SK, Herrera AC, Panis C, Lima TM, Souza HP (2015) PGC-1β regulates HER2-overexpressing breast cancer cells proliferation by metabolic and redox pathways. Tumour Biol 37:6035-44. | LEAK ROUTINE ET | ROX | Intact cells | Human | Genital Other cell lines |
Lee 2015 Methods Mol Biol | 2015 | Lee W, Kelly RD, Yeung KY, Cagnone G, McKenzie M, John JC (2015) Analysis of mitochondrial DNA in induced pluripotent and embryonic stem cells. Methods Mol Biol 1330:219-52. | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Stem cells |
Rodrigues 2016 Biochem J | 2015 | Rodrigues MF, Obre E, Melo FH, Santos-Jr GC, Galina A, Jasiulionis MG, Rossignol R, Rumjanek FD, Amoedo ND (2016) Enhanced OXPHOS, glutaminolysis and beta-oxidation constitute the metastatic phenotype of melanoma cells. https://doi.org/10.1042/BJ20150645 | LEAK ROUTINE OXPHOS ET | F N S ROX | Permeabilized cells Intact cells | Mouse | Endothelial;epithelial;mesothelial cell Other cell lines |
Kawalec 2015 PLoS One | 2015 | Kawalec M, Boratyńska-Jasińska A, Beręsewicz M, Dymkowska D, Zabłocki K, Zabłocka B (2015) Mitofusin 2 deficiency affects energy metabolism and mitochondrial biogenesis in MEF cells. PLoS One 10:e0134162. | LEAK ROUTINE ET | Permeabilized cells | Mouse | Fibroblast | |
Sundaram 2015 Mol Microbiol | 2015 | Sundaram V, Petkova MI, Pujol-Carrion N, Boada J, de la Torre-Ruiz MA (2015) Tor1, Sch9 and PKA downregulation in quiescence rely on Mtl1 to preserve mitochondrial integrity and cell survival. Mol Microbiol 97:93-109. | LEAK ROUTINE ET | ROX | Intact cells | Saccharomyces cerevisiae | |
Kasvandik 2015 J Proteome Res | 2015 | Kasvandik S, Samuel K, Peters M, Eimre M, Peet N, Roost AM, Padrik L, Paju K, Peil L, Salumets A (2015) Deep quantitative proteomics reveals extensive metabolic reprogramming and cancer-like changes of ectopic endometriotic stromal cells. J Proteome Res 15:572-84. | LEAK ROUTINE ET | ROX | Human | Genital Other cell lines | |
Du 2015 J Biol Chem | 2015 | Du J, Rountree A, Cleghorn WM, Contreras L, Lindsay KJ, Sadilek M, Gu H, Djukovic D, Raftery D, Satrustegui J, Kanow M, Chan L, Tsang SH, Sweet IR, Hurley JB (2015) Phototransduction influences metabolic flux and nucleotide metabolism in mouse retina. J Biol Chem 291:4698-710. | LEAK ROUTINE OXPHOS ET | N ROX | Isolated mitochondria | Mouse | Nervous system Islet cell;pancreas;thymus |
Tesori 2015 Sci Rep | 2015 | Tesori V, Piscaglia AC, Samengo D, Barba M, Bernardini C, Scatena R, Pontoglio A, Castellini L, Spelbrink JN, Maulucci G, Puglisi MA, Pani G, Gasbarrini A (2015) The multikinase inhibitor Sorafenib enhances glycolysis and synergizes with glycolysis blockade for cancer cell killing. Sci Rep 5:9149. | LEAK ROUTINE ET | Intact cells | Rat | Liver Other cell lines Stem cells | |
Bock 2015 Thesis | 2015 | Bock UB (2015) Auswirkung von normobarer Hyperoxie auf die mitochondriale Atmung von Alveolarmakrophagen. Dissertation p80. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Intact cells | Mouse | Lung;gill Macrophage-derived |
Plecita-Hlavata 2015 Am J Respir Cell Mol Biol | 2015 | Plecitá-Hlavatá L, Tauber J, Li M, Zhang H, Flockton AR, Pullamsetti SS, Chelladurai P, D'alessandro A, El Kasmi KC, Ježek P, Stenmark KR (2015) Constitutive reprogramming of fibroblast mitochondrial metabolism in pulmonary hypertension. Am J Respir Cell Mol Biol 55:47-57. | LEAK ROUTINE OXPHOS ET | N CIV Other combinations | Isolated mitochondria Intact cells | Human Bovines | Endothelial;epithelial;mesothelial cell Fibroblast |
Khiati 2015 Proc Natl Acad Sci U S A | 2015 | Khiati S, Baechler SA, Factor VM, Zhang H, Huang SY, Dalla Rosa I, Sourbier C, Neckers L, Thorgeirsson SS, Pommier Y (2015) Lack of mitochondrial topoisomerase I (TOP1mt) impairs liver regeneration. Proc Natl Acad Sci U S A 112:11282-7. | LEAK ROUTINE ET | Intact cells | Human | Endothelial;epithelial;mesothelial cell Other cell lines | |
Schoettl 2015 Mol Metab | 2015 | Schöttl T, Kappler L, Fromme T, Klingenspor M (2015) Limited OXPHOS capacity in white adipocytes is a hallmark of obesity in laboratory mice irrespective of the glucose tolerance status. Mol Metab 4:631-42. | LEAK ROUTINE OXPHOS ET | F N S ROX | Isolated mitochondria Intact cells | Mouse | Fat Other cell lines |
Hals 2015 PLoS One | 2015 | Hals IK, Bruerberg SG, Ma Z, Scholz H, Björklund A, Grill V (2015) Mitochondrial respiration in insulin-producing β-cells: general characteristics and adaptive effects of hypoxia. PLoS One 10:e0138558. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Rat | Islet cell;pancreas;thymus Other cell lines |
Six 2015 Cell Death Dis | 2015 | Six E, Lagresle-Peyrou C, Susini S, De Chappedelaine C, Sigrist N, Sadek H, Chouteau M, Cagnard N, Fontenay M, Hermine O, Chomienne C, Reynier P, Fischer A, André-Schmutz I, Gueguen N, Cavazzana M (2015) AK2 deficiency compromises the mitochondrial energy metabolism required for differentiation of human neutrophil and lymphoid lineages. Cell Death Dis 6:e1856. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells Other cell lines |
Hagl 2015 Molecules | 2015 | Hagl S, Berressem D, Bruns B, Sus N, Frank J, Eckert GP (2015) Beneficial Effects of Ethanolic and Hexanic Rice Bran Extract on Mitochondrial Function in PC12 Cells and the Search for Bioactive Components. Molecules 20(9):16524-39. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells | Rat | Nervous system Other cell lines |
Cassina 2015 Biol Reprod | 2015 | Cassina AM, Silveira P, Cantu L, Montes JM, Radi R, Sapiro R (2015) Defective human sperm cells are associated with mitochondrial dysfunction and oxidant production. Biol Reprod 93:119. | LEAK ROUTINE ET | ROX | Human | Genital | |
Lehtola 2015 Master's Thesis | 2015 | Lehtola A (2015) Main protein component of high density lipoprotein, apolipoprotein A1, modulates leukocyte cell respiration. Master's Thesis 1-44. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Intact cells Permeabilized cells | Human | Blood cells Other cell lines Lymphocyte |
Taferner 2015 PLoS One | 2015 | Taferner A, Pircher H, Koziel R, von Grafenstein S, Baraldo G, Palikaras K, Liedl KR, Tavernarakis N, Jansen-Dürr P (2015) FAH domain containing protein 1 (FAHD-1) is required for mitochondrial function and locomotion activity in C. elegans. PLoS One 10(8):e0134161. | ROUTINE | Intact organism | Caenorhabditis elegans Nematodes | ||
Garama 2015 Mol Cell Biol | 2015 | Garama DJ, Harris TJ, White CL, Rossello FJ, Abdul-Hay M, Gough DJ, Levy DE (2015) A synthetic lethal interaction between glutathione synthesis and mitochondrial reactive oxygen species provides a tumor-specific vulnerability dependent on STAT3. Mol Cell Biol 35:3646-56. | LEAK ROUTINE ET | Intact cells | Mouse | Endothelial;epithelial;mesothelial cell Fibroblast | |
Ikaga 2015 Biochem Biophys Rep | 2015 | Ikaga R, Namekatac I, Kotiadisd VN, Ogawab H, Duchend MR, Tanakac H, Iida-Tanakab N (2015) Knockdown of aquaporin-8 induces mitochondrial dysfunction in 3T3-L1 cells. Biochem Biophys Rep 4:187–95. | LEAK ROUTINE ET | CIV ROX | Intact cells | Mouse | Fat Other cell lines |
Martinez 2015 Thesis | 2015 | Martínez Gasca B (2015) Generacion de modelos celulares para el estudio del efecto fenotipico de la variacion genetica en el mtDNA. Thesis 1-35. | ROUTINE | Intact cells | Human | Liver Other cell lines |