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	Year	Reference	Coupling	Pathway	Preparation	Organism	Tissue;cell
Hagl 2015 Neurochem Int	2015	Hagl S, Kocher A, Schiborr C, Kolesova N, Frank J, Eckert GP (2015) Curcumin micelles improve mitochondrial function in neuronal PC12 cells and brains of NMRI mice - Impact on bioavailability. Neurochem Int 89:234-42.	LEAK OXPHOS ET	N S CIV	Isolated mitochondria	Mouse	Nervous system
Hanssen 2015 Diabetes	2015	Hanssen MJ, van der Lans AA, Brans B, Hoeks J, Jardon KM, Schaart G, Mottaghy FM, Schrauwen P, van Marken Lichtenbelt WD (2015) Short-term cold acclimation recruits brown adipose tissue in obese humans. Diabetes 65:1179-89.	LEAK OXPHOS ET	F N NS Other combinations	Permeabilized tissue	Human	Skeletal muscle
Hansson 2015 Eur J Pharmacol	2015	Hansson MJ, Llwyd O, Morin D, de Paulis D, Arnoux T, Gouarné C, Koul S, Engblom H, Bordet T, Tissier R, Arheden H, Erlinge D, Halestrap AP, Berdeaux A, Pruss RM, Schaller S (2015) Differences in the profile of protection afforded by TRO40303 and mild hypothermia in models of cardiac ischemia/reperfusion injury. Eur J Pharmacol 760:7-19.	LEAK OXPHOS ET	N S NS	Permeabilized tissue	Pig	Heart
Boss 2015 US Patent	2015	Boss OD, Crisan M, Giacobino JP, (2015) Brown adipocyte progenitors in human sceletal muscle. US Patent US 2015/0240206 A1.	LEAK ROUTINE ET	ROX	Permeabilized cells	Human Mouse	Skeletal muscle Endothelial;epithelial;mesothelial cell Fat
Zelenka 2015 Oxid Med Cell Longev	2015	Zelenka J, Dvořák A, Alán L (2015) L-lactate protects skin fibroblasts against aging-associated mitochondrial dysfunction via mitohormesis. Oxid Med Cell Longev 2015:351698.	LEAK ROUTINE ET	N S	Isolated mitochondria Intact cells	Rat	Liver Endothelial;epithelial;mesothelial cell Fibroblast
Khera 2015 Placenta	2015	Khera A, Dong LF, Holland OJ, Vanderlelie J, Pasdar EA, Neuzil J, Perkins AV (2015) Selenium supplementation induces mitochondrial biogenesis in trophoblasts. Placenta 36:863-9.	LEAK ROUTINE OXPHOS ET	N S CIV	Permeabilized cells Intact cells	Human	Genital Other cell lines
Porter 2015 Burns	2015	Porter C, Herndon DN, Bhattarai N, Ogunbileje JO, Szczesny B, Szabo C, Toliver-Kinsky T, Sidossis LS (2015) Differential acute and chronic effects of burn trauma on murine skeletal muscle bioenergetics. Burns 42:112-22.	LEAK OXPHOS ET	NS Other combinations	Permeabilized tissue	Mouse	Skeletal muscle
Ikaga 2015 Biochem Biophys Rep	2015	Ikaga R, Namekatac I, Kotiadisd VN, Ogawab H, Duchend MR, Tanakac H, Iida-Tanakab N (2015) Knockdown of aquaporin-8 induces mitochondrial dysfunction in 3T3-L1 cells. Biochem Biophys Rep 4:187–95.	LEAK ROUTINE ET	CIV ROX	Intact cells	Mouse	Fat Other cell lines
Du 2015 J Biol Chem	2015	Du J, Rountree A, Cleghorn WM, Contreras L, Lindsay KJ, Sadilek M, Gu H, Djukovic D, Raftery D, Satrustegui J, Kanow M, Chan L, Tsang SH, Sweet IR, Hurley JB (2015) Phototransduction influences metabolic flux and nucleotide metabolism in mouse retina. J Biol Chem 291:4698-710.	LEAK ROUTINE OXPHOS ET	N ROX	Isolated mitochondria	Mouse	Nervous system Islet cell;pancreas;thymus
Nelson 2015 Master Thesis	2015	Nelson MB (2015) The role of receptors for advanced glycation end-products (RAGE) and ceramide in cardiovascular disease. Master Thesis 1-53.	LEAK OXPHOS ET	N S NS	Permeabilized cells Permeabilized tissue	Mouse Rat	Heart Other cell lines
Assmann 2014 PhD Thesis	2015	Assmann N (2015) Impact of Fanconi-associated protein on the mitochonrial proteome. PhD Thesis 1-111.	LEAK ROUTINE OXPHOS ET	F N S CIV NS ROX	Permeabilized cells Intact cells	Pig	Kidney Other cell lines
Lourenco 2015 Front Aging Neurosci	2015	Lourenço CF, Ledo A, Dias C, Barbosa RM, Laranjinha J (2015) Neurovascular and neurometabolic derailment in aging and Alzheimer's disease. Front Aging Neurosci 7:103.	ROUTINE ET	ROX	Intact cells	Mouse	Nervous system
Lisak 2015 Cell Death Differ	2015	Lisak D, Schacht T, Gawlitza A, Albrecht P, Aktas O, Koop B, Gliem M, Hofstetter HH, Zanger K, Bultynck G, Parys JB, De Smedt H, Kindler T, Adams-Quack P, Hahn M, Waisman A, Reed JC, Hövelmeyer N, Methner A (2015) BAX inhibitor-1 is a Ca²⁺ channel critically important for immune cell function and survival. Cell Death Differ 23:358-68.	LEAK ROUTINE ET	ROX	Intact cells	Mouse	Blood cells Lymphocyte
Porter 2015 Am J Physiol Endocrinol Metab	2015	Porter C, Hurren NM, Cotter MV, Bhattarai N, Reidy PT, Dillon EL, Durham WJ, Tuvdendorj D, Sheffield-Moore M, Volpi E, Sidossis LS, Rasmussen BB, Børsheim E (2015) Mitochondrial respiratory capacity and coupling control decline with age in human skeletal muscle. Am J Physiol Endocrinol Metab 309:E224-32.	LEAK OXPHOS ET	F N NS Other combinations	Permeabilized tissue	Human	Skeletal muscle
Wessels 2015 Am J Physiol	2015	Wessels B, van den Broek NM, Ciapaite J, Houten SM, Wanders RJA, Nicolay K, Prompers JJ (2015) Carnitine supplementation in high-fat diet-fed rats does not ameliorate lipid-induced skeletal muscle mitochondrial dysfunction in vivo. Am J Physiol 309(7):E670-8.	LEAK OXPHOS ET	F N	Isolated mitochondria	Rat	Skeletal muscle
Dahl 2015 Acta Physiol (Oxf)	2015	Dahl R, Larsen S, Dohlmann TL, Qvortrup K, Helge JW, Dela F, Prats C (2015) Three dimensional reconstruction of the human skeletal muscle mitochondrial network as a tool to assess mitochondrial content and structural organization. Acta Physiol (Oxf) 213:145-55.	LEAK OXPHOS ET	N CIV NS	Permeabilized tissue	Human	Skeletal muscle
Smolkova 2015 Int J Biochem Cell Biol	2015	Smolková K, Dvořák A, Zelenka J, Vítek L, Ježek P (2015) Reductive carboxylation and 2-hydroxyglutarate formation by wild-type IDH2 in breast carcinoma cells. Int J Biochem Cell Biol 65:125-33.	LEAK ROUTINE ET	ROX	Intact cells	Human	Endothelial;epithelial;mesothelial cell Other cell lines
Weidinger 2015 Antioxid Redox Signal	2015	Weidinger A, Müllebner A, Paier-Pourani J, Banerjee A*, Miller I, Lauterböck L, Duvigneau JC, Skulachev VP, Redl H, Kozlov AV (2015) Vicious inducible nitric oxide synthase-mitochondrial reactive oxygen species cycle accelerates inflammatory response and causes liver injury in rats. Antioxid Redox Signal 22:572-86.	LEAK OXPHOS ET	N S	Homogenate	Rat	Liver
Sheldon 2015 Am J Physiol Gastrointest Liver Physiol	2015	Sheldon RD, Padilla J, Jenkins NT, Laughlin MH, Rector RS (2015) Chronic NOS inhibition accelerates NAFLD progression in an obese rat model. Am J Physiol Gastrointest Liver Physiol 308:G540-9.	LEAK OXPHOS ET	N NS	Isolated mitochondria	Rat	Liver
Maiti 2015 PhD Thesis	2015	Maiti P (2015) The role of caseinolytic mitochondrial matrix peptidase proteolytic subunit (CLPP) in regulation of mitochondrial ribosome biogenesis in mammals. PhD Thesis 1-120.	LEAK OXPHOS ET	N S NS ROX	Isolated mitochondria	Mouse	Heart
Vincent 2015 Front Physiol	2015	Vincent G, Lamon S, Gant N, Vincent PJ, MacDonald JR, Markworth JF, Edge JA, Hickey AJ (2015) Changes in mitochondrial function and mitochondria associated protein expression in response to 2-weeks of high intensity interval training. Front Physiol 6:51.	LEAK OXPHOS ET	N S ROX	Permeabilized tissue	Human	Skeletal muscle
Ortiz 2015 J Pineal Res	2015	Ortiz F, Acuña-Castroviejo D, Doerrier C, Dayoub JC, López LC, Venegas C, García JA, López A, Volt H, Luna-Sánchez M, Escames G (2015) Melatonin blunts the mitochondrial/NLRP3 connection and protects against radiation-induced oral mucositis. J Pineal Res 58:34-49.	LEAK OXPHOS ET	N S	Homogenate Isolated mitochondria
Beier 2015 FASEB J	2015	Beier UH, Angelin A, Akimova T, Wang L, Liu Y, Xiao H, Koike MA, Hancock SA, Bhatti TR, Han R, Jiao J, Veasey SC, Sims CA, Baur JA, Wallace DC, Hancock WW (2015) Essential role of mitochondrial energy metabolism in Foxp3⁺ T-regulatory cell function and allograft survival. FASEB J 29:2315-26. https://doi.org/10.1096/fj.14-268409	LEAK OXPHOS ET	N S NS ROX	Homogenate	Mouse	Nervous system
Flatters 2015 Prog Mol Biol Transl Sci	2015	Flatters SJ (2015) The contribution of mitochondria to sensory processing and pain. Prog Mol Biol Transl Sci 131:119-46.	OXPHOS ET	N S CIV NS	Homogenate Isolated mitochondria	Rat	Nervous system
Montero 2015 J Physiol	2015	Montero D, Cathomen A, Jacobs RA, Flück D, de Leur J, Keiser S, Bonne T, Kirk N, Lundby AK, Lundby C (2015) Haematological rather than skeletal muscle adaptations contribute to the increase in peak oxygen uptake induced by moderate endurance training. J Physiol 593:4677-88.	OXPHOS ET		Permeabilized tissue	Human	Skeletal muscle
Jeger 2015 BioMed Res Internat	2015	Jeger V, Brandt S, Porta F, Jakob SM, Takala J, Djafarzadeh S (2015) Dose response of Endotoxin on hepatocyte and muscle mitochondrial respiration in vitro. BioMed Res Internat Article ID 353074:1-13.	LEAK ROUTINE OXPHOS ET	N S CIV NS ROX	Permeabilized cells Isolated mitochondria Intact cells	Human	Skeletal muscle Liver Other cell lines
Ehinger 2015 J Neurol	2015	Ehinger JK, Morota S, Hansson MJ, Paul G, Elmér E (2015) Mitochondrial dysfunction in blood cells from amyotrophic lateral sclerosis patients. J Neurol 262:1493-503.	LEAK ROUTINE OXPHOS ET	N S CIV NS ROX	Permeabilized cells Intact cells	Human	Blood cells Lymphocyte Platelet
Hals 2015 PLoS One	2015	Hals IK, Bruerberg SG, Ma Z, Scholz H, Björklund A, Grill V (2015) Mitochondrial respiration in insulin-producing β-cells: general characteristics and adaptive effects of hypoxia. PLoS One 10:e0138558.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Permeabilized cells Intact cells	Rat	Islet cell;pancreas;thymus Other cell lines
Ziak 2015 Mitochondrion	2015	Ziak J, Krajcova A, Jiroutkova K, Nemcova V, Dzupa V, Duska F (2015) Assessing the function of mitochondria in cytosolic context in human skeletal muscle: Adopting high-resolution respirometry to homogenate of needle biopsy tissue samples. Mitochondrion 21:106-12.	LEAK OXPHOS ET	N S NS ROX	Homogenate Isolated mitochondria	Human	Skeletal muscle
Senyilmaz 2015 Nature	2015	Senyilmaz D, Virtue S, Xu X, Tan CY, Griffin JL, Miller AK, Vidal-Puig A, Teleman AA (2015) Regulation of mitochondrial morphology and function by stearoylation of TFR1. Nature 525:124-8.	OXPHOS ET	N S CIV NS	Permeabilized tissue	Drosophila
Kluckova 2015 Methods Mol Biol	2015	Kluckova K, Dong L, Bajzikova M, Rohlena J, Neuzil J (2015) Evaluation of respiration of mitochondria in cancer cells exposed to mitochondria-targeted agents. Methods Mol Biol 1265:181-94.	LEAK OXPHOS ET	N S NS ROX	Permeabilized cells Homogenate Intact cells	Mouse	Endothelial;epithelial;mesothelial cell Genital Other cell lines
Zhunussova 2015 Am J Cancer Res	2015	Zhunussova A, Sen B, Friedman L, Tuleukhanov S, Brooks AD, Sensenig R, Orynbayeva Z (2015) Tumor microenvironment promotes dicarboxylic acid carrier-mediated transport of succinate to fuel prostate cancer mitochondria. Am J Cancer Res 5:1665-79.	ROUTINE ET	S	Permeabilized cells Intact cells	Human Rat	Endothelial;epithelial;mesothelial cell Genital Other cell lines
Christiansen 2015 J Vet Med Sci	2015	Christiansen LB, Dela F, Koch J, Yokota T (2015) Tissue-specific and substrate-specific mitochondrial bioenergetics in feline cardiac and skeletal muscles. J Vet Med Sci 77:669-75.	LEAK OXPHOS ET	F N S CIV NS Other combinations ROX	Permeabilized tissue	Cat	Heart Skeletal muscle
Errea 2015 J Neuroinflammation	2015	Errea O, Moreno B, Gonzalez-Franquesa A, Garcia-Roves PM, Villoslada P (2015) The disruption of mitochondrial axonal transport is an early event in neuroinflammation. J Neuroinflammation 12:152.	LEAK OXPHOS ET	N S CIV NS ROX	Homogenate	Mouse	Nervous system
Warne 2015 J Biol Chem	2015	Warne J, Pryce G, Hill JM, Shi X, Lennerås F, Puentes F, Kip M, Hilditch L, Walker P, Simone MI, Chan AWE, Towers GJ, Coker AR, Duchen MR, Szabadkai G, Baker D, Selwood DL (2015) Selective inhibition of the mitochondrial permeability transition pore protects against neuro-degeneration in experimental multiple sclerosis. J Biol Chem 291:4356-73.	LEAK OXPHOS ET	N ROX	Isolated mitochondria	Mouse	Liver
Negmadjanov 2015 PLOS ONE	2015	Negmadjanov U, Godic Z, Rizvi F, Emelyanova L, Ross G, Richards J, Holmuhamedov EL, Jahangir A (2015) TGF-β1-mediated differentiation of fibroblasts is associated with increased mitochondrial content and cellular respiration. PLOS ONE 10:e0123046. doi: 10.1371/journal.pone.0123046.	LEAK ROUTINE ET	ROX		Mouse	Fibroblast
Drechsler 2015 Intensive Care Medicine Experimental	2015	Drechsler S, Weixelbaumer KM, Weidinger A, Raeven P, Khadem A, Redl H, van Griensven M, Bahrami S, Remick D, Kozlov A, Osuchowski MF (2015) Why do they die? Comparison of selected aspects of organ injury and dysfunction in mice surviving and dying in acute abdominal sepsis. Intensive Care Medicine Experimental 3:12.	LEAK OXPHOS ET	N S	Homogenate	Mouse	Liver Kidney
Llobet 2015 Dis Model Mech	2015	Llobet L, Toivonen JM, Montoya J, Ruiz-Pesini E, López-Gallardo E (2015) OXPHOS xenobiotics alter adipogenic differentiation at concentrations found in human blood. Dis Model Mech 8:1441-55.	LEAK ROUTINE ET		Intact cells	Human	Fat Stem cells
Bock 2015 Thesis	2015	Bock UB (2015) Auswirkung von normobarer Hyperoxie auf die mitochondriale Atmung von Alveolarmakrophagen. Dissertation p80.	LEAK ROUTINE OXPHOS ET	N S CIV NS ROX	Permeabilized cells Intact cells	Mouse	Lung;gill Macrophage-derived
Labieniec-Watala 2015 Int J Pharm Sci Res	2015	Labieniec-Watala M, Przygodzki T, Siewiera K, Podsedek A, Watala C (2015) Facts and artifacts in the evaluation of the anti-diabetic activity of spent hop extract in rat hearts in the “experimental model of diabetes. Int J Pharm Sci Res 1:106.	LEAK OXPHOS ET	S ROX	Isolated mitochondria	Rat	Heart
Miwa 2015 Free Radic Biol Med	2015	Miwa S, Treumann A, Bell A, Vistoli G, Nelson G, Hay S, von Zglinicki T (2015) Carboxylesterase converts Amplex red to resorufin: Implications for mitochondrial H₂O₂ release assays. Free Radic Biol Med 90:173-83.	LEAK OXPHOS ET	N S ROX	Isolated mitochondria	Mouse	Liver
Iftikar 2015 Comp Biochem Physiol A Mol Integr Physiol	2015	Iftikar FI, Morash AJ, Cook DG, Herbert NA, Hickey AJ (2015) Temperature acclimation of mitochondria function from the hearts of a temperate wrasse (Notolabrus celidotus). Comp Biochem Physiol A Mol Integr Physiol 184:46-55.	LEAK OXPHOS ET	N S CIV NS ROX	Permeabilized tissue	Fishes	Heart
Houben 2015 Mitochondrion	2015	Houben R, Leleu C, Fraipont A, Serteyn D, Votion DM (2015) Determination of muscle mitochondrial respiratory capacity in Standardbred racehorses as an aid to predicting exertional rhabdomyolysis. Mitochondrion 24:99-104.	OXPHOS ET	N S NS ROX	Permeabilized tissue	Horse	Skeletal muscle
Patil 2015 J Nutr Biochem	2015	Patil YN, Dille KN, Burk DH, Cortez CC, Gettys TW (2015) Cellular and molecular remodeling of inguinal adipose tissue mitochondria by dietary methionine restriction. J Nutr Biochem 26:1235-47.	LEAK OXPHOS ET	F N S Gp ROX	Isolated mitochondria	Mouse	Skeletal muscle Liver Fat
Seillier 2015 EMBO Mol Med	2015	Seillier M, Pouyet L, N'Guessan P, Nollet M, Capo F, Guillaumond F, Peyta L, Dumas JF, Varrault A, Bertrand G, Bonnafous S, Tran A, Meur G, Marchetti P, Ravier MA, Dalle S, Gual P, Muller D, Rutter GA, Servais S, Iovanna JL, Carrier A (2015) Defects in mitophagy promote redox-driven metabolic syndrome in the absence of TP53INP1. EMBO Mol Med 7:802-18.	LEAK ROUTINE OXPHOS ET	F CIV NS ROX	Permeabilized cells Intact cells	Human Mouse	Fibroblast
Canto 2015 Curr Protoc Mouse Biol	2015	Cantó C, Garcia-Roves PM (2015) High-resolution respirometry for mitochondrial characterization of ex vivo mouse tissues. Curr Protoc Mouse Biol 5:135-53.	LEAK OXPHOS ET	N S NS	Permeabilized tissue Homogenate	Mouse	Heart Skeletal muscle Nervous system Liver Fat
Coupling-control protocol	2015	Gnaiger E (2015) From PCP to CCP. Mitochondr Physiol Network 2015-01-11.	LEAK ROUTINE OXPHOS ET
Hansen 2015 Shock	2015	Hansen ME, Simmons KJ, Tippetts TS, Thatcher MO, Saito RR, Hubbard ST, Trumbull AM, Parker BA, Taylor OJ, Bikman BT (2015) Lipopolysaccharide disrupts mitochondrial physiology in skeletal muscle via disparate effects on sphingolipid metabolism. Shock 44:585-92.	OXPHOS LEAK ET	N NS ROX	Permeabilized cells Permeabilized tissue	Mouse	Skeletal muscle Other cell lines
Ramos-Filho 2015 PLoS One	2015	Ramos-Filho D, Chicaybam G, de-Souza-Ferreira E, Guerra Martinez C, Kurtenbach E, Casimiro-Lopes G, Galina A (2015) High intensity interval training (HIIT) induces specific changes in respiration and electron leakage in the mitochondria of different rat skeletal muscles. PLoS One 10:e0131766.	LEAK OXPHOS ET	F N S Gp NS ROX	Permeabilized tissue	Rat	Skeletal muscle
Schirris 2015 Cell Metab	2015	Schirris TJ, Renkema GH, Ritschel T, Voermans NC, Bilos A, van Engelen BG, Brandt U, Koopman WJ, Beyrath JD, Rodenburg RJ, Willems PH, Smeitink JA, Russel FG (2015) Statin-induced myopathy is associated with mitochondrial complex III inhibition. Cell Metab 22:399-407.	ROUTINE OXPHOS ET	N S Gp CIV NS ROX	Permeabilized cells	Human Mouse	Skeletal muscle Other cell lines
Bowen 2015 Eur J Heart Fail	2015	Bowen TS, Rolim NP, Fischer T, Baekkerud FH, Medeiros A, Werner S, Brønstad E, Rognmo O, Mangner N, Linke A, Schuler G, Silva GJ, Wisløff U, Adams V (2015) Heart failure with preserved ejection fraction induces molecular, mitochondrial, histological, and functional alterations in rat respiratory and limb skeletal muscle. Eur J Heart Fail 17:263-72.	LEAK OXPHOS ET	N NS	Permeabilized tissue	Rat	Skeletal muscle
Madsen 2015 Nat Commun	2015	Madsen CT, Sylvestersen KB, Young C, Larsen SC, Poulsen JW, Andersen MA, Palmqvist EA, Hey-Mogensen M, Jensen PB, Treebak JT, Lisby M, Nielsen ML (2015) Biotin starvation causes mitochondrial protein hyperacetylation and partial rescue by the SIRT3-like deacetylase Hst4p. Nat Commun 6:7726.	ROUTINE ET		Intact cells	Saccharomyces cerevisiae
Van Rahden 2015 Am J Hum Genet	2015	van Rahden VA, Fernandez-Vizarra E, Alawi M, Brand K, Fellmann F, Horn D, Zeviani M, Kutsche K (2015) Mutations in NDUFB11, encoding a complex I component of the mitochondrial respiratory chain, cause microphthalmia with linear skin defects syndrome. Am J Hum Genet 96:640-50.	LEAK ROUTINE ET		Intact cells	Human	HeLa
Kilbaugh 2015 J Am Heart Assoc	2015	Kilbaugh TJ, Sutton RM, Karlsson M, Hansson MJ, Naim MY, Morgan RW, Bratinov G, Lampe JW, Nadkarni VM, Becker LB, Margulies SS, Berg RA (2015) Persistently altered brain mitochondrial bioenergetics after apparently successful resuscitation from cardiac arrest. J Am Heart Assoc 4(9) pii: e002232.	LEAK OXPHOS ET	N S CIV NS ROX	Homogenate	Pig	Nervous system
Park 2015 Proc Natl Acad Sci USA	2015	Park JH, Kang HJ, Lee YK, Kang H, Kim J, Chung JH, Chang JS, McPherron AC, Lee SB (2015) Inactivation of EWS reduces PGC-1α protein stability and mitochondrial homeostasis. Proc Natl Acad Sci USA 112:6074-9.	LEAK ROUTINE ET	ROX	Intact cells	Mouse	Fat
Antoun 2015 JIMD Rep	2015	Antoun G, McBride S, Vanstone JR, Naas T, Michaud J, Redpath S, McMillan HJ, Brophy J, Daoud H, Chakraborty P, Dyment D, Holcik M, Harper ME, Lines MA (2015) Detailed biochemical and bioenergetic characterization of FBXL4-related encephalomyopathic mitochondrial DNA depletion. JIMD Rep 27:1-9.	LEAK OXPHOS ET	F N S CIV NS ROX	Permeabilized tissue	Human	Skeletal muscle
Duicu 2015 Biomed Res Int	2015	Duicu OM, Lighezan R, Sturza A, Ceausu RA, Borza C, Vaduva A, Noveanu L, Gaspar M, Ionac A, Feier H, Muntean DM, Mornos C (2015) Monoamine oxidases as potential contributors to oxidative stress in diabetes: time for a study in patients undergoing heart surgery. Biomed Res Int 2015:515437.	LEAK OXPHOS ET	N S ROX	Permeabilized tissue	Human	Heart
Hecker 2015 Methods Mol Biol	2015	Hecker M, Sommer N, Mayer K (2015) Assessment of short- and medium-chain fatty acids on mitochondrial function in severe Inflammation. Methods Mol Biol 1265:389-96.	LEAK ROUTINE ET	ROX	Intact cells	Human	Endothelial;epithelial;mesothelial cell
Dueregger 2015 PLoS One	2015	Dueregger A, Schöpf B, Eder T, Höfer J, Gnaiger E, Aufinger A, Kenner L, Perktold B, Ramoner R, Klocker H, Eder IE (2015) Differential utilization of dietary fatty acids in benign and malignant cells of the prostate. PLoS One 10(8):e0135704.	LEAK ROUTINE OXPHOS ET	F N NS ROX	Permeabilized cells Permeabilized tissue	Human	Genital Other cell lines
Hollis 2015 Proc Natl Acad Sci U S A	2015	Hollis F, van der Kooij MA, Zanoletti O, Lozano L, Cantó C, Sandi C (2015) Mitochondrial function in the brain links anxiety with social subordination. Proc Natl Acad Sci U S A 112:15486-91.	OXPHOS ET	N S NS ROX	Homogenate	Rat	Nervous system
Garama 2015 Mol Cell Biol	2015	Garama DJ, Harris TJ, White CL, Rossello FJ, Abdul-Hay M, Gough DJ, Levy DE (2015) A synthetic lethal interaction between glutathione synthesis and mitochondrial reactive oxygen species provides a tumor-specific vulnerability dependent on STAT3. Mol Cell Biol 35:3646-56.	LEAK ROUTINE ET		Intact cells	Mouse	Endothelial;epithelial;mesothelial cell Fibroblast
Bonsignore 2015 Mech Ageing Dev	2015	Bonsignore LA, Tooley JG, Van Hoose PM, Wang E, Cheng A, Cole MP, Schaner Tooley CE (2015) NRMT1 knockout mice exhibit phenotypes associated with impaired DNA repair and premature aging. Mech Ageing Dev 146-148:42-52.	LEAK OXPHOS ET	N ROX	Isolated mitochondria	Mouse	Liver
Banerjee 2015 Placenta	2015	Banerjee A, Weidinger A, Hofer M, Steinborn R, Lindenmair A, Hennerbichler-Lugscheider S, Eibl J, Redl H, Kozlov AV, Wolbank S (2015) Different metabolic activity in placental and reflected regions of the human amniotic membrane. Placenta 36:1329-32.	ROUTINE OXPHOS ET	N	Intact cells Permeabilized tissue	Human	Genital
Hanssen 2015 Diabetologia	2015	Hanssen MJ, Wierts R, Hoeks J, Gemmink A, Brans B, Mottaghy FM, Schrauwen P, van Marken Lichtenbelt WD (2015) Glucose uptake in human brown adipose tissue is impaired upon fasting-induced insulin resistance. Diabetologia 58:586-95.	LEAK ET	F	Isolated mitochondria	Human	Skeletal muscle
Harris 2015 Diabetes	2015	Harris LA, Skinner JR, Shew TM, Pietka TA, Abumrad NA, Wolins NE (2015) Perilipin 5-driven lipid droplet accumulation in skeletal muscle stimulates the expression of fibroblast growth factor 21. Diabetes 64:2757-68.	OXPHOS ET	N S NS ROX	Permeabilized tissue	Mouse	Skeletal muscle
Schwarzkopf 2015 Neuroscience	2015	Schwarzkopf TM, Koch K, Klein J (2015) Reduced severity of ischemic stroke and improvement of mitochondrial function after dietary treatment with the anaplerotic substance triheptanoin. Neuroscience 300:201-9.	LEAK OXPHOS ET	N S CIV NS ROX	Isolated mitochondria	Mouse	Nervous system
Kruse 2015 Aging Cell	2015	Kruse SE, Karunadharma PP, Basisty N, Johnson R, Beyer RP, MacCoss MJ, Rabinovitch PS, Marcinek DJ (2015) Age modifies respiratory complex I and protein homeostasis in a muscle type-specific manner. Aging Cell 15:89-99.	LEAK OXPHOS ET	N S CIV NS ROX	Permeabilized tissue	Mouse	Skeletal muscle
Victorino 2015 Tumour Biol	2015	Victorino VJ, Barroso WA, Assunção AK, Cury V, Jeremias IC, Petroni R, Chausse B, Ariga SK, Herrera AC, Panis C, Lima TM, Souza HP (2015) PGC-1β regulates HER2-overexpressing breast cancer cells proliferation by metabolic and redox pathways. Tumour Biol 37:6035-44.	LEAK ROUTINE ET	ROX	Intact cells	Human	Genital Other cell lines
Hwang 2015 EMBO Mol Med	2015	Hwang S, Disatnik MH, Mochly-Rosen D (2015) Impaired GAPDH-induced mitophagy contributes to the pathology of Huntington's disease. EMBO Mol Med 7:1307-26.	LEAK OXPHOS ET	ROX	Intact cells	Rat	Nervous system Other cell lines
Grabez 2015 J Anim Sci	2015	Grabež V, Kathri M, Phung V, Moe KM, Slinde E, Skaugen M, Saarem K, Egelandsdal B (2015) Protein expression and oxygen consumption rate of early postmortem mitochondria relate to meat tenderness. J Anim Sci 93:1967-79.	LEAK OXPHOS ET	F N S NS Other combinations ROX	Permeabilized tissue	Bovines	Skeletal muscle
Moore 2015 PhD Thesis	2015	Moore D (2015) Biostabilization of lipid bilayers: dealing with water stress in embryos of Artemia franciscana. PhD Thesis 1-111.	LEAK OXPHOS ET	S	Isolated mitochondria	Rat	Liver
Sobotka 2015 Physiol Res	2015	Sobotka O, Drahota Z, Kučera O, Endlicher R, Rauchová H, Červinková Z (2015) The effect of α-tocopheryl succinate on succinate respiration in rat liver mitochondria. Physiol Res 64 Suppl 5:S609-15.	OXPHOS ET	S	Permeabilized cells Homogenate Isolated mitochondria	Rat	Liver
Pasdar 2015 PLoS One	2015	Pasdar EA, Smits M, Stapelberg M, Bajzikova M, Stantic M, Goodwin J, Yan B, Stursa J, Kovarova J, Sachaphibulkij K, Bezawork-Geleta A, Sobol M, Filimonenko A, Tomasetti M, Zobalova R, Hozak P, Dong LF, Neuzil J (2015) Characterisation of mesothelioma-initiating cells and their susceptibility to anti-cancer agents. PLoS One 10:e0119549.	LEAK ROUTINE OXPHOS ET	N S NS	Permeabilized cells Intact cells	Human Mouse	Endothelial;epithelial;mesothelial cell Other cell lines
Gnaiger 2015 Scand J Med Sci Sports	2015	Gnaiger E, Boushel R, Søndergaard H, Munch-Andersen T, Damsgaard R, Hagen C, Díez-Sánchez C, Ara I, Wright-Paradis C, Schrauwen P, Hesselink M, Calbet JAL, Christiansen M, Helge JW, Saltin B (2015) Mitochondrial coupling and capacity of oxidative phosphorylation in skeletal muscle of Inuit and caucasians in the arctic winter. https://doi.org/10.1111/sms.12612	LEAK OXPHOS ET	F N S ROX	Permeabilized tissue	Human	Skeletal muscle
Khiati 2015 Proc Natl Acad Sci U S A	2015	Khiati S, Baechler SA, Factor VM, Zhang H, Huang SY, Dalla Rosa I, Sourbier C, Neckers L, Thorgeirsson SS, Pommier Y (2015) Lack of mitochondrial topoisomerase I (TOP1mt) impairs liver regeneration. Proc Natl Acad Sci U S A 112:11282-7.	LEAK ROUTINE ET		Intact cells	Human	Endothelial;epithelial;mesothelial cell Other cell lines
Ruiz-Perez 2015 J Biol Chem	2015	Ruiz-Pérez MV, Medina MÁ, Urdiales JL, Keinänen TA, Sánchez-Jiménez F (2015) Polyamine metabolism is sensitive to glycolysis inhibition in human neuroblastoma cells. J Biol Chem 290:6106-19.	LEAK ROUTINE ET	ROX	Intact cells	Human	Nervous system Other cell lines Neuroblastoma
Kelly 2015 Biotechnol J	2015	Kelly PS, Breen L, Gallagher C, Kelly S, Henry M, Lao NT, Meleady P, O'Gorman D, Clynes M, Barron N (2015) Re-programming CHO cell metabolism using miR-23 tips the balance towards a highly productive phenotype. Biotechnol J 10:1029-40.	LEAK ROUTINE OXPHOS ET	N S CIV NS ROX	Intact cells Permeabilized cells		CHO
Hendricks 2015 Thesis	2015	Hendricks EW (2015) The impact of aging and estrogen therapy on synaptic mitochondrial bioenergetics in an Alzheimer's mouse model. Master Thesis 1-67.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Permeabilized cells Isolated mitochondria Intact cells	Mouse	Nervous system
Schoettl 2015 Mol Metab	2015	Schöttl T, Kappler L, Fromme T, Klingenspor M (2015) Limited OXPHOS capacity in white adipocytes is a hallmark of obesity in laboratory mice irrespective of the glucose tolerance status. Mol Metab 4:631-42.	LEAK ROUTINE OXPHOS ET	F N S ROX	Isolated mitochondria Intact cells	Mouse	Fat Other cell lines
Sjoevall 2015 US Patent	2015	Sjövall F, Ehinger J, Hansson M, Elmer E, Batcheller DG (2018) Mitochondrial toxicity test. US Patent US20150253306 A1.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Intact cells Permeabilized cells	Human	Blood cells Macrophage-derived Platelet
Wessels 2015 Diabetes Obes Metab	2015	Wessels B, Ciapaite J, van den Broek NM, Houten SM, Nicolay K, Prompers JJ (2015) Pioglitazone treatment restores in vivo muscle oxidative capacity in a rat model of diabetes. Diabetes Obes Metab 17:52-60.	LEAK OXPHOS ET	F N S	Isolated mitochondria	Rat	Skeletal muscle
Christiansen 2015 Am J Physiol Heart Circ Physiol	2015	Christiansen LB, Dela F, Koch J, Hansen CN, Leifsson PS, Yokota T (2015) Impaired cardiac mitochondrial oxidative phosphorylation and enhanced mitochondrial oxidative stress in feline hypertrophic cardiomyopathy. Am J Physiol Heart Circ Physiol 308:H1237-47.	LEAK OXPHOS ET	F N S CIV NS ROX	Permeabilized tissue Isolated mitochondria	Cat	Heart Skeletal muscle
Cassina 2015 Biol Reprod	2015	Cassina AM, Silveira P, Cantu L, Montes JM, Radi R, Sapiro R (2015) Defective human sperm cells are associated with mitochondrial dysfunction and oxidant production. Biol Reprod 93:119.	LEAK ROUTINE ET	ROX		Human	Genital
Lark 2015 Front Physiol	2015	Lark DS, Reese LR, Ryan TE, Torres MJ, Smith CD, Lin CT, Neufer PD (2015) Protein kinase A governs oxidative phosphorylation kinetics and oxidant emitting potential at complex I. https://doi.org/10.3389/fphys.2015.00332	LEAK ET OXPHOS	N S	Permeabilized tissue Isolated mitochondria	Mouse	Skeletal muscle Liver
Jiroutkova 2015 Crit Care	2015	Jiroutková K, Krajčová A, Ziak J, Fric M, Waldauf P, Džupa V, Gojda J, Němcova-Fürstová V, Kovář J, Elkalaf M, Trnka J, Duška F (2015) Mitochondrial function in skeletal muscle of patients with protracted critical illness and ICU-acquired weakness. Crit Care 19:448.	LEAK OXPHOS ET	N S Gp CIV NS Other combinations ROX	Homogenate	Human	Skeletal muscle
Cagnone 2015 Methods Mol Biol	2015	Cagnone G, Vaghjiani V, Lee W, Sun C, Johnson J, Yeung KY, St John JC (2015) Analysis of the mitochondrial DNA and its replicative capacity in induced pluripotent stem cells. Methods Mol Biol 1357:231-67.	LEAK ROUTINE ET	ROX	Intact cells	Human	Stem cells
Burtscher 2015 Mitochondrion	2015	Burtscher J, Zangrandi L, Schwarzer C, Gnaiger E (2015) Differences in mitochondrial function in homogenated samples from healthy and epileptic specific brain tissues revealed by high-resolution respirometry. Mitochondrion 25:104-12.	LEAK OXPHOS ET	N S CIV NS ROX	Permeabilized tissue Homogenate	Mouse	Nervous system
Orynbayeva 2015 Nanomedicine (Lond)	2015	Orynbayeva Z, Sensenig R, Polyak B (2015) Metabolic and structural integrity of magnetic nanoparticle-loaded primary endothelial cells for targeted cell therapy. Nanomedicine (Lond) 10:1555-68.	LEAK ROUTINE ET	ROX	Intact cells	Rat	Endothelial;epithelial;mesothelial cell
Petrus 2015 Can J Physiol Pharmacol	2015	Petruş A, Duicu OM, Sturza A, Noveanu L, Kiss L, Dănilă M, Baczkó I, Muntean DM, Jost N (2015) Modulation of mitochondrial respiratory function and ROS production by novel benzopyran analogues. Can J Physiol Pharmacol 93:811-8.	LEAK OXPHOS ET	N ROX	Isolated mitochondria	Rat	Heart
Castelein 2014 Exp Gerontol	2014	Castelein N, Muschol M, Dhondt I, Cai H, De Vos WH, Dencher NA, Braeckman BP (2014) Mitochondrial efficiency is increased in axenically cultured Caenorhabditis elegans. Exp Gerontol 56:26-36.	LEAK OXPHOS ET	N S NS	Isolated mitochondria	Caenorhabditis elegans
Iglesias-Gonzalez 2014 PhD Thesis	2014	Iglesias-Gonzalez J (2014) Neurotoxicity induced by oxidative stress and aluminium in relation to Parkinson’s disease: a mitochondrial bioenergetic approach by high-resolution respirometry. PhD Thesis 1-242.	LEAK OXPHOS ET	N S NS ROX	Isolated mitochondria	Rat	Nervous system
Brandt 2014 Chem Biol Interact	2014	Brandt AP, do Rocio Andrade Pires A, Rocha ME, Noleto GR, Acco A, de Souza CE, Echevarria A, Dos Santos Canuto AV, Cadena SM (2014) Sydnone SYD-1 affects the metabolic functions of isolated rat hepatocytes. Chem Biol Interact 218C:107-14.	LEAK ROUTINE ET	ROX	Intact cells	Rat	Liver
Shama 2014 Funct Ecol	2014	Shama LNS, Strobel A, Mark FC, Wegner KM (2014) Transgenerational plasticity in marine sticklebacks: maternal effects mediate impacts of a warming ocean. Funct Ecol 28:1482–93.	LEAK OXPHOS ET	N ROX	Permeabilized tissue	Fishes	Heart
Dogan 2014 Cell Metab	2014	Dogan SA, Pujol C, Maiti P, Kukat A, Wang S, Hermans S, Senft K, Wibom R, Rugarli EI, Trifunovic A (2014) Tissue-specific loss of DARS2 activates stress responses independently of respiratory chain deficiency in the heart. Cell Metab 19:458-69.	LEAK OXPHOS ET	N S	Permeabilized tissue Isolated mitochondria	Mouse	Heart Skeletal muscle Liver
Phielix 2014 Diabetologia	2014	Phielix E, Jelenik T, Nowotny P, Szendroedi J, Roden M (2014) Reduction of non-esterified fatty acids improves insulin sensitivity and lowers oxidative stress, but fails to restore oxidative capacity in type 2 diabetes: a randomised clinical trial. Diabetologia 57:572-81.	LEAK OXPHOS ET	N NS	Permeabilized tissue Isolated mitochondria	Human	Skeletal muscle
Kukat 2014 PLoS Genet	2014	Kukat A, Dogan SA, Edgar D, Mourier A, Jacoby C, Maiti P, Mauer J, Becker C, Senft K, Wibom R, Kudin AP, Hultenby K, Flögel U, Rosenkranz S, Ricquier D, Kunz WS, Trifunovic A (2014) Loss of UCP2 attenuates mitochondrial dysfunction without altering ROS production and uncoupling activity. https://doi.org/10.1371/journal.pgen.1004385	LEAK OXPHOS ET	F N S NS ROX	Isolated mitochondria	Mouse	Heart
Doridot 2014 Antioxid Redox Signal	2014	Doridot LD Chatre LD, Ducat A, Vilotte JL, Lombes A, Méhats C, Barbaux S, Calicchio R, Ricchetti M, Vaiman D (2014) Nitroso-redox balance and mitochondrial homeostasis are regulated by STOX1, a pre-eclampsia associated gene. Antioxid Redox Signal 21:819-34.	LEAK ROUTINE ET	ROX		Human	Endothelial;epithelial;mesothelial cell Other cell lines
Karabatsiakis 2014 Transl Psychiatry	2014	Karabatsiakis A, Boeck C, Salinas-Manrique J, Kolassa S, Calzia E, Dietrich DE, Kolassa IT (2014) Mitochondrial respiration in peripheral blood mononuclear cells correlates with depressive subsymptoms and severity of major depression. Transl Psychiatry 4:e397.	LEAK ROUTINE ET	ROX	Intact cells	Human	Blood cells
Hoevenaars 2014 Mol Nutr Food Res	2014	Hoevenaars FP, Bekkenkamp-Grovenstein M, Janssen RJ, Heil SG, Bunschoten A, Hoek-van den Hil EF, Snaas-Alders S, Teerds K, van Schothorst EM, Keijer J (2014) Thermoneutrality results in prominent diet-induced body weight differences in C57BL/6J mice, not paralleled by diet-induced metabolic differences. Mol Nutr Food Res 58:799-807.	LEAK OXPHOS ET	N NS	Isolated mitochondria	Mouse	Skeletal muscle
Hort 2014 Biochimie	2014	Hort MA, Straliotto MR, de Oliveira J, Amoêdo ND, da Rocha JB, Galina A, Ribeiro-do-Valle RM, de Bem AF (2014) Diphenyl diselenide protects endothelial cells against oxidized low density lipoprotein-induced injury: Involvement of mitochondrial function. Biochimie 105:172-81.	LEAK ROUTINE ET		Intact cells	Bovines	Other cell lines
Zambrano 2014 J Cell Biol	2014	Zambrano A, García-Carpizo V, Gallardo ME, Villamuera R, Gómez-Ferrería MA, Pascual A, Buisine N, Sachs LM, Garesse R, Aranda A (2014) The thyroid hormone receptor induces DNA damage and premature senescence. J Cell Biol 204:129-46.	LEAK OXPHOS ET	N ROX	Intact cells	Mouse
Cotoia 2014 PLoS One	2014	Cotoia A, Scrima R, Gefter JV, Piccoli C, Cinnella G, Dambrosio M, Fink MP, Capitanio N (2014) p-Hydroxyphenylpyruvate, an intermediate of the Phe/ Tyr catabolism, improves mitochondrial oxidative metabolism under stressing conditions and prolongs survival in rats subjected to profound hemorrhagic shock. PLoS One 9:e90917.	LEAK ROUTINE ET		Intact cells	Rat
Tippets 2014 BMC Cardiovasc Disord	2014	Tippetts TS, Winden DR, Swensen AC, Nelson MB, Thatcher MO, Saito RR, Condie TB, Simmons KJ, Judd AM, Reynolds PR, Bikman BT (2014) Cigarette smoke increases cardiomyocyte ceramide accumulation and inhibits mitochondrial respiration. BMC Cardiovasc Disord 14:165.	LEAK OXPHOS ET	N S NS ROX	Permeabilized cells Permeabilized tissue Isolated mitochondria	Mouse Rat	Heart Other cell lines
Schoerner 2014 Thesis University Giessen	2014	Schörner S (2014) Changes in function of mitochondrial respiratory chain in pulmonary artery smooth muscle cells under conditions of chronic hypoxia : measurements by respirometry and remission-spectrophotometry. Thesis University Giessen 130 pp.	LEAK ROUTINE ET	ROX		Rabbit	Endothelial;epithelial;mesothelial cell
DeLany 2014 J Clin Endocrinol Metab	2014	DeLany JP, Dube JJ, Standley RA, Distefano G, Goodpaster BH, Stefanovic-Racic M, Coen PM, Toledo FG (2014) Racial differences in peripheral insulin sensitivity and mitochondrial capacity in the absence of obesity. J Clin Endocrinol Metab 99:4307-14.	LEAK OXPHOS ET	Other combinations	Permeabilized tissue	Human	Skeletal muscle
Larsen 2014 Anal Biochem	2014	Larsen S, Kraunsøe R, Gram M, Gnaiger E, Helge JW, Dela F (2014) The best approach: homogenization or manual permeabilization of human skeletal muscle fibers for respirometry? Anal Biochem 446:64-8.	LEAK OXPHOS ET	N NS	Permeabilized tissue Homogenate	Human Mouse	Skeletal muscle
Miquel 2014 Free Radic Biol Med	2014	Miquel E, Cassina A, Martínez-Palma L, Souza JM, Bolatto C, Rodríguez-Bottero S, Logan A, Smith RA, Murphy MP, Barbeito L, Radi R, Cassina P (2014) Neuroprotective effects of the mitochondria-targeted antioxidant MitoQ in a model of inherited amyotrophic lateral sclerosis. Free Radic Biol Med 70:204-13.	LEAK OXPHOS ET	NS ROX	Permeabilized tissue	Mouse	Skeletal muscle Nervous system
Hagl 2014 J Alzheimers Dis b	2014	Hagl S, Heinrich M, Kocher A, Schiborr C, Frank J, Eckert GP (2014) Curcumin micelles improve mitochondrial function in a mouse model of Alzheimer’s disease. J Alzheimers Dis 1:80-3.	LEAK OXPHOS ET	N S CIV NS ROX	Isolated mitochondria	Mouse	Nervous system
Chini 2014 Clin Cancer Res	2014	Chini CC, Gonzalez Guerrico A, Nin V, Camacho-Pereira J, Escande C, Barbosa M, Chini EN (2014) Targeting of NAD metabolism in pancreatic cancer cells: potential novel therapy for pancreatic tumors. Clin Cancer Res 20:120-30.	ROUTINE ET		Intact cells	Human	Islet cell;pancreas;thymus Other cell lines
Chicco 2014 J Exp Biol	2014	Chicco AJ, Le CH, Schlater AE, Nguyen AD, Kaye SD, Beals JW, Scalzo RL, Bell C, Gnaiger E, Costa DP, Crocker DE, Kanatous SB (2014) High fatty acid oxidation capacity and phosphorylation control despite elevated leak and reduced respiratory capacity in northern elephant seal muscle mitochondria. J Exp Biol 217:2947-55.	LEAK OXPHOS ET	F N S NS	Permeabilized tissue	Human Other mammals	Skeletal muscle
Broeker 2014 Thesis	2014	Broeker C (2014) Mitochondriopathien als Ursache des renalen Fanconi-Syndroms. Dissertation 85pp.	LEAK OXPHOS ET	N CIV NS ROX	Permeabilized cells	Pig	Kidney Other cell lines
Porter 2014 Am J Physiol	2014	Porter C, Herndon DN, Børsheim E, Chao T, Reidy P, Borack M, Rasmussen BB, Chondronikola M, Saraf M, Sidossis LS (2014) Uncoupled skeletal muscle mitochondria contribute to hypermetabolism in severely burned adults. Am J Physiol 307:E462-7.	LEAK OXPHOS ET	N NS	Permeabilized tissue	Human	Skeletal muscle
Davoudi 2014 PLoS One	2014	Davoudi M, Kotarsky H, Hansson E, Fellman V (2014) Complex I function and supercomplex formation are preserved in liver mitochondria despite progressive Complex III deficiency. PLoS One 9:e86767.	LEAK OXPHOS ET	N S ROX	Isolated mitochondria	Mouse	Liver
Jiroutkova 2014 Intensive Care Medicine Experimental	2014	Jiroutkova K, Ziak J, Krajcova A, Fric M, Dzupa V, Duska F (2014) The role of mitochondrial dysfunction in the pathophysiology of icu-acquired weakness. Intensive Care Med 2:29.	LEAK OXPHOS ET	N S		Human	Skeletal muscle
Ost 2014 PLoS One	2014	Ost M, Werner F, Dokas J, Klaus S, Voigt A (2014) Activation of AMPKa2 is not crucial for mitochondrial uncoupling-induced metabolic effects but required to maintain skeletal muscle integrity. PLoS One 14:e94689.	LEAK OXPHOS ET	F N NS	Permeabilized tissue	Mouse	Skeletal muscle
Davoudi 2014 PhD Thesis	2014	Davoudi M (2014) Effect of experimental complex III deficiency on respiratory chain assembly and function. PhD Thesis 1-65.	LEAK OXPHOS ET	N S	Isolated mitochondria	Mouse	Liver
Matallo 2014 Nitric Oxide	2014	Matallo J, Vogt J, McCook O, Wachter U, Tillmans F, Groeger M, Szabo C, Georgieff M, Radermacher P, Calzia E (2014) Sulfide-inhibition of mitochondrial respiration at very low oxygen concentrations. Nitric Oxide 15:79-84.	ROUTINE ET		Intact cells	Mouse	Lung;gill Macrophage-derived
Mourier 2014 Hum Mol Genet	2014	Mourier A, Ruzzenente B, Brandt T, Kühlbrandt W, Larsson NG (2014) Loss of LRPPRC causes ATP synthase deficiency. Hum Mol Genet 23:2580-92.	LEAK OXPHOS ET	N S	Isolated mitochondria	Mouse	Heart
Hasenour 2014 J Biol Chem	2014	Hasenour CM, Ridley DE, Hughey CC, James FD, Donahue EP, Shearer J, Viollet B, Foretz M, Wasserman DH (2014) 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside (AICAR) effect on glucose production, but not energy metabolism, is independent of hepatic AMPK in vivo. J Biol Chem 289:5950-9.	LEAK OXPHOS ET	N ROX	Isolated mitochondria	Mouse	Liver
Krumschnabel 2014 Methods Enzymol	2014	Krumschnabel G, Eigentler A, Fasching M, Gnaiger E (2014) Use of safranin for the assessment of mitochondrial membrane potential by high-resolution respirometry and fluorometry. Methods Enzymol 542:163-81. https://doi.org/10.1016/B978-0-12-416618-9.00009-1	LEAK OXPHOS ET	N S ROX	Homogenate	Mouse	Nervous system
Baggio 2014 Nucleic Acids Res	2014	Baggio F, Bratic A, Mourier A, Kauppila TE, Tain LS, Kukat C, Habermann B, Partridge L, Larsson NG5 (2014) Drosophila melanogaster LRPPRC2 is involved in coordination of mitochondrial translation. Nucleic Acids Res 42:13920-38.	LEAK OXPHOS ET	N S Gp CIV Other combinations	Permeabilized tissue	Drosophila Hexapods
Zachariah 2014 Diabetes	2014	Zachariah Tom R, Garcia-Roves PM, Sjögren RJ, Jiang LQ, Holmström MH, Deshmukh AS, Vieira E, Chibalin AV, Björnholm M, Zierath JR (2014) Effects of AMPK activation on insulin sensitivity and metabolism in leptin-deficient ob/ob mice. Diabetes 63:1560-71.	LEAK OXPHOS ET	N NS	Permeabilized tissue	Mouse	Skeletal muscle
Afshordel 2014 Prostaglandins Leukot Essent Fatty Acids	2014	Afshordel S, Hagl S, Werner D, Roehner N, Koegel D, Bazan NG, Eckert GP (2014) Omega-3 polyunsaturated fatty acids improve mitochondrial dysfunction in brain aging - impact of Bcl-2 and NPD-1 like metabolites. Prostaglandins Leukot Essent Fatty Acids 92:23-31.	LEAK OXPHOS ET	N S CIV NS ROX	Isolated mitochondria	Mouse	Nervous system
Hereng 2014 Human Reprod	2014	Hereng TH, Elgstoen KBP, Eide L, Rosendal KR, Skalhegg BS (2014) Serum albumin and HCO3 2 regulate separate pools of ATP in human spermatozoa. Human Reprod 29:918-30.	LEAK ROUTINE ET		Intact cells	Human	Genital
Nunez-Figueredo 2014 Brain Res Bull	2014	Nunez-Figueredo Y, Pardo-Andreu GL, Ramirez-Sanchez J, Delgado-Hernandez R, Ochoa-Rodriguez E, Verdecia-Reyes Y, Naal Z, Muller AP, Portela LV, Souza DO (2014) Antioxidant effects of JM-20 on rat brain mitochondria and synaptosomes: Mitoprotection against Ca²⁺-induced mitochondrial impairment. Brain Res Bull 109:68-76.	ET	N S	Isolated mitochondria	Rat	Nervous system
Boutant 2014 Mol Metab	2014	Boutant M, Joffraud M, Kulkarni SS, Garcia-Casarrubios E, Garcia-Roves PM, Ratajczak J, Fernandez-Marcos PJ, Valverde AM, Serrano M, Canto C (2014) SIRT1 enhances glucose tolerance by potentiating brown adipose tissue function. Mol Metab 4:118-31.	LEAK OXPHOS ET	N S NS ROX	Permeabilized tissue Homogenate	Mouse	Skeletal muscle Liver Fat
Casanova 2014 J Nutr Biochem	2014	Casanova E, Baselga-Escudero L, Ribas-Latre A, Cedó L, Arola-Arnal A, Pinent M, Bladé C, Arola L, Salvadó MJ (2014) Chronic intake of proanthocyanidins and docosahexaenoic acid improves skeletal muscle oxidative capacity in diet-obese rats. J Nutr Biochem 25:1003–10.	LEAK OXPHOS ET	F N S NS	Isolated mitochondria	Rat	Skeletal muscle
Schiffer 2014 FASEB J	2014	Schiffer TA, Ekblom B, Lundberg JO, Weitzberg E, Larsen FJ (2014) Dynamic regulation of metabolic efficiency explains tolerance to acute hypoxia in humans. FASEB J 28:4303-11.	LEAK OXPHOS ET	N S	Isolated mitochondria	Human	Skeletal muscle
Felser 2014 Toxicology II	2014	Felser A, Lindinger PW, Schnell D, Kratschmar DV, Odermatt A, Mies S, Jenö P, Krähenbühl S (2014) Hepatocellular toxicity of benzbromarone: effects on mitochondrial function and structure. Toxicology 324:136-46.	LEAK ROUTINE OXPHOS ET	N S ROX	Intact cells	Human	Liver Other cell lines
Beiral 2014 Cell Transplant	2014	Beiral HJ, Rodrigues-Ferreira C, Fernandes AM, Gonsalez SR, Mortari NC, Takiya CM, Sorenson MM, Figueiredo-Freitas C, Galina A, Vieyra A (2014) The impact of stem cells on electron fluxes, proton translocation and ATP synthesis in kidney mitochondria after ischemia/reperfusion. Cell Transplant 23:207-20.	LEAK OXPHOS ET	S	Isolated mitochondria	Rat	Kidney Stem cells
Cedikova 2014 Evid Based Complement Alternat Med	2014	Cedikova M, Miklikova M, Stachova L, Grundmanova M, Tuma Z, Vetvicka V, Zech N, Kralickova M, Kuncova J (2014) Effects of the Czech propolis on sperm mitochondrial function. Evid Based Complement Alternat Med 248768.	LEAK OXPHOS ET	F N S CIV NS ROX	Permeabilized cells	Human	Genital
Glaser 2014 Thesis	2014	Glaser V (2014) Efeitos da hiperglicemia cronica e seus metabolitos, metilglioxal e produtos terminais de glicacao, na fisiologia e dinamica mitochondrial no sistema nervoso central. PhD Thesis 1-117.	LEAK ROUTINE ET	ROX	Intact cells	Rat	Nervous system Other cell lines
Solinas 2014 Mech Ageing Dev	2014	Solinas P, Fujioka H, Radivoyevitch T, Tandler B, Hoppel CL (2014) Aging effects on oxidative phosphorylation in rat adrenocortical 3 mitochondria. Mech Ageing Dev 138:10-4.	LEAK OXPHOS ET	N S CIV NS	Isolated mitochondria	Rat	Kidney
Thatcher 2014 Am J Physiol Endocrinol Metab	2014	Thatcher MO, Tippetts TS, Nelson MB, Swensen AC, Winden DR, Hansen ME, Anderson MC, Johnson IE, Porter JP, Reynolds PR, Bikman BT (2014) Ceramides mediate cigarette smoke-induced metabolic disruption in mice. Am J Physiol Endocrinol Metab 307:E919-27.	LEAK OXPHOS ET	N S NS ROX	Permeabilized cells Permeabilized tissue	Human Mouse	Skeletal muscle
Sjoevall 2014 PLoS One	2014	Sjövall F, Morota S, Asander Frostner E, Hansson Magnus J, Elmer E (2014) Cytokine and nitric oxide levels in patients with sepsis - temporal evolvement and relation to platelet mitochondrial respiratory function. PLoS One 9:e97673.	LEAK OXPHOS ET	N S CIV NS ROX	Permeabilized cells	Human	Blood cells Platelet
Fiuza 2014 Free Radic Res	2014	Fiuza B, Subelzú N, Calcerrada P, Straliotto MR, Piacenza L, Cassina A, Rocha JB, Radi R, de Bem AF, Peluffo G (2014) Impact of SIN-1-derived peroxynitrite flux on endothelial cell redox homeostasis and bioenergetics: protective role of diphenyl diselenide via induction of peroxiredoxins. Free Radic Res 49:122-32.	LEAK ROUTINE ET		Intact cells	Bovines	Endothelial;epithelial;mesothelial cell
Wessels 2014 PLoS One	2014	Wessels B, Ciapaite J, van den Broek NMA, Nicolay K, Prompers JJ (2014) Metformin impairs mitochondrial function in skeletal muscle of both lean and diabetic rats in a dose-dependent manner. PLoS One 9:e100525.	LEAK OXPHOS ET	N S	Isolated mitochondria	Rat	Skeletal muscle
Carriere 2014 Diabetes	2014	Carrière A, Jeanson Y, Berger-Müller S, André M, Chenouard V, Arnaud E, Barreau C, Walther R, Galinier A, Wdziekonski B, Villageois P, Louche K, Collas P, Moro C, Dani C, Villarroya F, Casteilla L (2014) Browning of white adipose cells by intermediate metabolites: an adaptive mechanism to alleviate redox pressure. Diabetes 63:3253-65.	LEAK ROUTINE ET		Intact cells	Mouse	Fat
Rossato 2014 PLoS One	2014	Rossato FA, Zecchin KG, La Guardia PG, Ortega RM, Alberici LC, Costa RA, Catharino RR, Graner E, Castilho RF, Vercesi AE (2014) Fatty acid synthase inhibitors induce apoptosis in non-tumorigenic Melan-A cells associated with inhibition of mitochondrial respiration. PLoS One 9:e101060.	LEAK OXPHOS ET	N S CIV NS	Permeabilized cells Intact cells	Mouse	Endothelial;epithelial;mesothelial cell Other cell lines
Power 2014 Physiol Rep	2014	Power A, Pearson N, Pham T, Cheung C, Phillips A, Hickey A (2014) Uncoupling of oxidative phosphorylation and ATP synthase reversal within the hyperthermic heart. Physiol Rep pii:e12138.	LEAK OXPHOS ET	N NS	Isolated mitochondria	Rat	Heart
Di Noia 2014 J Biol Chem	2014	Di Noia MA, Todisco S, Cirigliano A, Rinaldi T, Agrimi G, Iacobazzi V, Palmieri F (2014) The human SLC25A33 and SLC25A36 genes of solute carrier family 25 encode two mitochondrial pyrimidine nucleotide transporters. J Biol Chem 289:33137-48.	ROUTINE ET		Intact cells	Saccharomyces cerevisiae
Chakraborty 2014 J Cardiovasc Dis	2014	Chakraborty M, Phillips ARJ, Macdonald J, Windsor JA, Hickey AJR (2014) Mitochondrial respiration in mononuclear cells and heart fibers in spontaneously hypertensive rats. J Cardiovasc Dis ISSN:2330-459.	LEAK ROUTINE OXPHOS ET	N S Gp CIV NS ROX	Permeabilized cells Permeabilized tissue	Rat	Heart Blood cells
Doerrier 2014 Life Sci	2014	Doerrier C, García JA, Volt H, Díaz-Casado ME, Lima-Cabello E, Ortiz F, Luna-Sánchez M, Escames G, López LC, Acuña-Castroviejo D (2014) Identification of mitochondrial deficits and melatonin targets in liver of septic mice by high-resolution respirometry. Life Sci 121:158-65.	LEAK OXPHOS ET	N S NS	Homogenate Isolated mitochondria	Mouse	Liver
Jelenik 2014 Diabetes	2014	Jelenik T, Séquaris G, Kaul K, Ouwens DM, Phielix E, Kotzka J, Knebel B, Weiß J, Reinbeck AL, Janke L, Nowotny P, Partke HJ, Zhang D, Shulman GI, Szendroedi J, Roden M (2014) Tissue-specific differences in the development of insulin resistance in a mouse model for type 1 diabetes. Diabetes 63:3856-67.	OXPHOS ET	N NS ROX	Permeabilized tissue Isolated mitochondria	Mouse	Skeletal muscle Liver
Ambrosio 2014 Free Radic Biol Med	2014	Ambrosio F, Brown E, Stolz D, Ferrari R, Goodpaster BH, Deasy B, Distefano G, Roperti A, Cheikhi A, Garciafigueroa Y, Barchowsky A (2014) Arsenic induces sustained impairment of skeletal muscle and muscle progenitor cell ultrastructure and bioenergetics. Free Radic Biol Med 74C:64-73.	LEAK OXPHOS ET	F N NS	Permeabilized tissue	Mouse	Skeletal muscle
Bayot 2014 Biochimie	2014	Bayot A, Gareil M, Chavatte L, Hamon MP, L'hermitte-Stead C, Beaumatin F, Priault M, Rustin P, Lombès A, Friguet B, Bulteau AL (2014) Effect of Lon protease knockdown on mitochondrial function in HeLa cells. Biochimie 100:38-47.	LEAK ROUTINE ET			Human	Endothelial;epithelial;mesothelial cell HeLa
Koenemann 2014 Dissertation	2014	Koenemann B (2014) Einfluss der Hyperglykämie auf die mitochondriale Atmung von Leberzellen septischer Mäuse mit und ohne Imeglimin. PhD Thesis 1-61.	LEAK OXPHOS ET	F N S NS Other combinations ROX	Homogenate	Mouse	Liver
Grimpo 2014 Comp Biochem Physiol A Mol Integr Physiol	2014	Grimpo K, Kutschke M, Kastl A, Meyer CW, Heldmaier G, Exner C, Jastroch M (2014) Metabolic depression during warm torpor in the Golden spiny mouse (Acomys russatus) does not affect mitochondrial respiration and hydrogen peroxide release. Comp Biochem Physiol A Mol Integr Physiol 167:7-14.	LEAK OXPHOS ET	S	Isolated mitochondria	Other mammals	Heart Skeletal muscle Liver Kidney
Vigueira 2014 Cell Rep	2014	Vigueira PA, McCommis KS, Schweitzer GG, Remedi MS, Chambers KT, Fu X, McDonald WG, Cole SL, Colca JR, Kletzien RF, Burgess SC, Finck BN (2014) Mitochondrial pyruvate carrier 2 hypomorphism in mice leads to defects in glucose-stimulated insulin secretion. Cell Rep 7:2042-53.	ET	N S	Isolated mitochondria	Mouse	Heart Kidney
Divakaruni 2014 Curr Protoc Toxicol	2014	Divakaruni AS, Rogers GW, Murphy AN (2014) Measuring mitochondrial function in permeabilized cells using the Seahorse XF Analyzer or a clark-type oxygen electrode. Curr Protoc Toxicol 60:25.2.1-25.2.16.	LEAK OXPHOS ET	F N S Gp CIV ROX	Permeabilized cells	Mouse	Skeletal muscle Other cell lines
Slinde 2014 freepatentsonline.com	2014	Slinde E, Egelandsdal B (2014) Meat treatment and preservation method. Freepatentsonline.com 14/128207.	LEAK OXPHOS ET	F N NS ROX	Permeabilized tissue	Bovines	Skeletal muscle
Casanova 2014 Biochim Biophys Acta	2014	Casanova E, Baselga-Escudero L, Ribas-Latre A, Arola-Arnal A, Bladé C, Arola L, Salvadó MJ (2014) Epigallocatechin gallate counteracts oxidative stress in docosahexaenoxic acid-treated myocytes. Biochim Biophys Acta 1837:783-91.	LEAK ROUTINE ET	N	Intact cells	Rat	Skeletal muscle Other cell lines
Serteyn 2014 Bioenergetics	2014	Serteyn D, de la Rebière de Pouyade G, Sandersen C, Salciccia A, Grulke S, Mouithys-Mickalad A, Franck T, Lejeune JP, Ceusters Justine D (2014) Muscle mitochondrial dysfunction in horses affected by acute laminitis. Bioenergetics 3:1-7.	LEAK OXPHOS ET	N S NS ROX	Permeabilized tissue	Horse	Skeletal muscle
Garratt 2014 Proc Natl Acad Sci U S A	2014	Garratt M, Pichaud N, Glaros EN, Kee AJ, Brooks RC (2014) Superoxide dismutase deficiency impairs olfactory sexual signaling and alters bioenergetic function in mice. Proc Natl Acad Sci U S A 111:8119-24.	LEAK OXPHOS ET	F N S CIV NS ROX	Permeabilized tissue	Mouse	Liver
De Palma 2014 Skelet Muscle	2014	De Palma C, Morisi F, Pambianco S, Assi E, Touvier T, Russo S, Perrotta C, Romanello V, Carnio S, Cappello V, Pellegrino P, Moscheni C, Bassi MT, Sandri M, Cervia D, Clementi E (2014) Deficient nitric oxide signalling impairs skeletal muscle growth and performance: involvement of mitochondrial dysregulation. Skelet Muscle 4:22.	LEAK OXPHOS ET	N S CIV NS	Permeabilized tissue Isolated mitochondria	Mouse	Skeletal muscle
Hecker 2014 JPEN	2014	Hecker M, Sommer N, Voigtmann H, Pak O, Mohr A, Wolf M, Vadász I, Herold S, Weissmann N, Morty R, Seeger W, Mayer K (2014) Impact of short- and medium-chain fatty acids on mitochondrial function in severe inflammation. J Parenter Enteral Nutr 38:587-94.	LEAK ROUTINE ET		Intact cells	Human	Endothelial;epithelial;mesothelial cell Blood cells HUVEC
Kivelae 2014 EMBO Mol Med	2014	Kivelä R, Bry M, Robciuc MR, Räsänen M, Taavitsainen M, Silvola JM, Saraste A, Hulmi JJ, Anisimov A, Mäyränpää MI, Lindeman JH, Eklund L, Hellberg S, Hlushchuk R, Zhuang ZW, Simons M, Djonov V, Knuuti J, Mervaala E, Alitalo K (2016) VEGF-B-induced vascular growth leads to metabolic reprogramming and ischemia resistance in the heart. EMBO Mol Med 6:307-21.	LEAK OXPHOS ET	F N S NS	Homogenate	Rat	Heart
Kramer 2014 J Vis Exp	2014	Kramer PA, Chacko BK, Ravi S, Johnson MS, Mitchell T, Darley-Usmar VM (2014) Bioenergetics and the oxidative burst: protocols for the isolation and evaluation of human leukocytes and platelets. J Vis Exp 2014 Mar 27(85). doi: 10.3791/51301.	LEAK ROUTINE ET		Intact cells	Human	Blood cells Platelet
Onukwufor 2013 J Exp Biol	2014	Onukwufor JO, Macdonald N, Kibenge F, Stevens D, Kamunde C (2013) Hypoxia-cadmium interactions on rainbow trout (Oncorhynchus mykiss) mitochondrial bioenergetics: attenuation of hypoxia-induced proton leak by low doses of cadmium. J Exp Biol 217:831-40.	LEAK OXPHOS ET	N	Isolated mitochondria	Fishes	Liver
Iftikar 2014 Thesis University of Auckland	2014	Iftikar FI (2014) Testing the role of heart mitochondrial stability and function in heart failure of ectotherms exposed to heat stress. Thesis University of Auckland:167pp.	LEAK OXPHOS ET	N CIV NS ROX	Permeabilized tissue	Fishes	Heart
Cordero-Reyes 2014 J Mol Cell Cardiol	2014	Cordero-Reyes AM, Gupte AA, Youker KA, Loebe M, Hsueh WA, Torre-Amione G, Taegtmeyer H, Hamilton DJ (2014) Freshly isolated mitochondria from failing human hearts exhibit preserved respiratory function. J Mol Cell Cardiol 68:98-105.	LEAK OXPHOS ET	N S ROX	Isolated mitochondria	Human	Heart
Brahma 2014 J Lipid Res	2014	Brahma MK, Adam RC, Pollak NM, Jaeger D, Zierler KA, Poecher N, Schreiber R, Romauch M, Moustafa T, Eder S, Ruelicke T, Preiss-Landl K, Lass A, Zechner R, Haemmerle G (2014) Fibroblast growth factor 21 is induced upon cardiac stress and alters cardiac lipid homeostasis. J Lipid Res 55:2229-41.	LEAK ROUTINE ET		Intact cells	Mouse Rat	Heart
Van Bergen 2014 Mitochondrion	2014	Van Bergen NJ, Blake RE, Crowston JG, Trounce IA (2014) Oxidative phosphorylation measurement in cell lines and tissues. Mitochondrion 15:24-33.	LEAK ROUTINE OXPHOS ET	N S NS	Permeabilized cells Isolated mitochondria Intact cells	Human Mouse	Nervous system Blood cells
Montaigne 2014 Circulation	2014	Montaigne D, Marechal X, Coisne A, Debry N, Modine T, Fayad G, Potelle C, El Arid JM, Mouton S, Sebti Y, Duez H, Preau S, Remy-Jouet I, Zerimech F, Koussa M, Richard V, Neviere R, Edme JL, Lefebvre P, Staels B (2014) Myocardial contractile dysfunction is associated with impaired mitochondrial function and dynamics in Type 2 Diabetic but not in obese patients. Circulation 130:554-64.	LEAK OXPHOS ET	F N S CIV NS	Permeabilized tissue	Human	Heart
Fletcher 2014 Med Sci Sports Exerc	2014	Fletcher JA, Meers GM, Linden MA, Kearney ML, Morris EM, Thyfault JP, Rector RS (2014) Impact of various exercise modalities on hepatic mitochondrial function. Med Sci Sports Exerc 46:1089-97.	LEAK OXPHOS ET	N S NS	Isolated mitochondria	Rat	Liver
Chu 2014 PLoS One	2014	Chu MJ, Hickey AJ, Tagaloa S, Zhang L, Dare AJ, MacDonald JR, Yeong ML, Bartlett AS, Phillips AR (2014) Ob/ob mouse livers show decreased oxidative phosphorylation efficiencies and anaerobic capacities after cold ischemia. PLoS One 9:e100609.	LEAK OXPHOS ET	N S CIV NS	Permeabilized tissue	Mouse	Liver
Diana 2014 Ann Surg	2014	Diana M, Noll E, Diemunsch P, Dallemagne B, Benahmed MA, Agnus V, Soler L, Barry B, Namer IJ, Demartines N, Charles AL, Geny B, Marescaux J (2014) Enhanced-reality video fluorescence: a real-time assessment of intestinal viability. Ann Surg 259:700-7.	ET	N S CIV Other combinations	Intact cells	Pig	Endothelial;epithelial;mesothelial cell
Corona 2014 Exp Neurol	2014	Corona JC, de Souza SC, Duchen MR (2014) PPARγ activation rescues mitochondrial function from inhibition of 2 complex I and loss of PINK1. Exp Neurol 253:16-27.	LEAK ROUTINE ET		Intact cells	Human	Neuroblastoma
Cheng 2014 Science	2014	Cheng SC, Quintin J, Cramer RA, Shepardson KM, Saeed S, Kumar V, Giamarellos-Bourboulis EJ, Martens JH, Rao NA, Aghajanirefah A, Manjeri GR6, Li Y, Ifrim DC, Arts RJ, van der Meer BM, Deen PM, Logie C, O'Neill LA, Willems P, van de Veerdonk FL, van der Meer JW, Ng A, Joosten LA, Wijmenga C, Stunnenberg HG, Xavier RJ, Netea MG (2014) mTOR- and HIF-1 α–mediated aerobic glycolysis as metabolic basis for trained immunity. Science 345:1250684.	LEAK ROUTINE ET			Human	Blood cells Other cell lines
Noncoupled respiration	2014	Gnaiger E (2014) Is respiration uncoupled - noncoupled - dyscoupled? Mitochondr Physiol Network 2014-04-18.	LEAK ET
Van Bree 2014 PhD Thesis	2014	van Bree B (2014) Mitochondria, lipotoxicity and skeletal muscle metabolism: implications for type 2 diabetes mellitus. PhD Thesis 1-150.	LEAK OXPHOS ET	F N	Isolated mitochondria	Mouse	Skeletal muscle
Gnaiger 2014 MitoPathways	2014	Gnaiger E (2014) Mitochondrial pathways and respiratory control. An introduction to OXPHOS analysis. 4^th ed. Mitochondr Physiol Network 19.12. Oroboros MiPNet Publications, Innsbruck:80 pp. — see 5^th edition: Gnaiger 2020 BEC MitoPathways.	LEAK ROUTINE OXPHOS ET	F N S Gp CIV NS ROX	Permeabilized cells Permeabilized tissue Homogenate Isolated mitochondria Intact cells	Human Mouse	Heart Skeletal muscle Fibroblast
Den Hollander 2014 Toxicol Sci	2014	den Hollander B, Sundström M, Pelander A, Ojanperä I, Mervaala E, Korpi ER, Kankuri E (2014) Keto amphetamine toxicity - focus on the redox reactivity of the cathinone designer drug mephedrone. Toxicol Sci 141:120-31.	LEAK OXPHOS ET	N S NS ROX	Homogenate	Mouse	Nervous system
Valenti 2014 Anal Biochem	2014	Valenti D, de Bari L, De Filippis B, Ricceri L, Vacca RA (2014) Preservation of mitochondrial functional integrity in mitochondria isolated from small cryopreserved mouse brain areas. Anal Biochem 444:25-31.	OXPHOS ET	N S ROX	Isolated mitochondria	Mouse	Nervous system
Khan 2014 J Comp Physiol	2014	Khan JR, Iftikar FI, Herbert NA, Gnaiger E, Hickey AJ (2014) Thermal plasticity of skeletal muscle mitochondrial activity and whole animal respiration in a common intertidal triplefin fish, Forsterygion lapillum (Family: Tripterygiidae). J Comp Physiol 184:991-1001.	LEAK OXPHOS ET	N S NS ROX	Permeabilized tissue	Fishes	Skeletal muscle
Boczek 2014 Biomed Res Int	2014	Boczek T, Lisek M, Ferenc B, Kowalski A, Wiktorska M, Zylinska L (2014) Silencing of plasma membrane Ca²⁺-ATPase isoforms 2 and 3 impairs energy metabolism in differentiating PC12 cells. Biomed Res Int 2014:735106.	LEAK ROUTINE ET			Rat	Nervous system Other cell lines
Konickova 2014 Annals Hepatol	2014	Konickova R, Vankova K, Vanikova J, Vanova K, Muchova L, Subhanova I, Zadoinova M, Zelenka J, Dvorak A, Kolar M,Strnad H, Rimpelova S, Ruml T, Wong RJ, Vitek L (2014) Anti-cancer effects of blue-green alga Spirulina platensis, a natural source of bilirubin-like tetrapyrrolic compounds. Annals Hepatol 13:273-83.	ROUTINE ET			Human	Other cell lines
Rudnicki 2014 United States Patent Application Publication	2014	Rudnicki MA, Yin Hang (2014) MICRORNA INHIBITORS. United States Patent Application Publication 1-49.	LEAK ROUTINE OXPHOS ET	F N S NS ROX	Permeabilized cells Intact cells	Mouse	Skeletal muscle Fat
Piel 2014 Acta Physiol (Oxf)	2014	Piel S, Ehinger JK, Elmér E, Hansson Magnus J (2014) Metformin induces lactate production in peripheral blood mononuclear cells and platelets through specific mitochondrial Complex I inhibition. Acta Physiol (Oxf) 213:171-80.	LEAK ROUTINE OXPHOS ET	N S CIV NS ROX	Permeabilized cells Intact cells	Human	Blood cells Other cell lines Platelet
Garnol 2014 Physiol Res	2014	Garnol T, Endlicher R, Kučera O, Drahota Z, Cervinková Z (2014) Impairment of mitochondrial function of rat hepatocytes by high fat diet and oxidative stress. Physiol Res 63:271-4.	LEAK OXPHOS ET	N S	Permeabilized cells Isolated mitochondria Intact cells	Rat	Liver
Abdurrachim 2014 Biochim Biophys Acta	2014	Abdurrachim D, Ciapaite J, Wessels B, Nabben M, Luiken JJ, Nicolay K, Prompers JJ (2014) Cardiac diastolic dysfunction in high-fat diet fed mice is associated with lipotoxicity without impairment of cardiac energetics in vivo. Biochim Biophys Acta 1842:1525-37.	LEAK OXPHOS ET	F N	Isolated mitochondria	Mouse	Heart
Fisar 2014 Toxicol Lett	2014	Fišar Z, Singh N, Hroudová J (2014) Cannabinoid-induced changes in respiration of brain mitochondria. Toxicol Lett 231:62-71.	LEAK OXPHOS ET	N S CIV ROX	Isolated mitochondria	Pig	Nervous system
Dube 2014 Am J Physiol Endocrinol Metab	2014	Dube JJ, Coen PM, DiStefano G, Chacon AC, Helbling NL, Desimone ME, Stafanovic-Racic M, Hames KC, Despines AA, Toledo FG, Goodpaster BH (2014) Effects of acute lipid overload on skeletal muscle insulin resistance, metabolic flexibility, and mitochondrial performance. Am J Physiol Endocrinol Metab 307:E1117-24.	LEAK OXPHOS ET		Permeabilized tissue	Human	Skeletal muscle
Pham 2014 Am J Physiol	2014	Pham T, Loiselle D, Power A, Hickey AJ (2014) Mitochondrial inefficiencies and anoxic ATP hydrolysis capacities in diabetic rat heart. Am J Physiol 307:C499–507.	LEAK OXPHOS ET	N NS ROX	Homogenate	Rat	Heart
Damiano 2014 PLoS One	2014	Damiano M, Gautier CA, Bulteau AL, Ferrando-Miguel R, Gouarne C, Paoli MG, Pruss R, Auchère F, L'Hermitte-Stead C, Bouillaud F, Brice A, Corti O, Lombès A (2014) Tissue- and cell-specific mitochondrial defect in Parkin- deficient mice. PLoS One 9:e99898.	LEAK OXPHOS ET	N ROX	Isolated mitochondria	Mouse	Nervous system
Logan 2014 Nat Genet	2014	Logan CV, Szabadkai G, Sharpe JA, Parry DA, Torelli S, Childs AM, Kriek M, Phadke R, Johnson CA, Roberts NY, Bonthron DT, Pysden KA, Whyte T, Munteanu I, Foley AR, Wheway G, Szymanska K, Natarajan S, Abdelhamed ZA, Morgan JE, Roper H, Santen GW, Niks EH, van der Pol WL, Lindhout D, Raffaello A, De Stefani D, den Dunnen JT, Sun Y, Ginjaar I, Sewry CA, Hurles M, Rizzuto R. UK10K Consortium, Duchen MR, Muntoni F, Sheridan E (2014) Loss-of-function mutations in MICU1 cause a brain and muscle disorder linked to primary alterations in mitochondrial calcium signaling. Nat Genet 46:188-93.	LEAK ROUTINE ET	ROX	Intact cells	Human	Fibroblast
Echevarría 2014 Biochem J	2014	Echevarría L, Clemente P, Hernández Sierra R, Gallardo ME, Fernández-Moreno MA, Garesse R (2014) Mammalian GatCAB is essential for mitochondrial translation 1 Glutamyl-tRNAGln amidotransferase is essential for mammalian mitochondrial translation in vivo. Biochem J 460:91-101.	LEAK ET	N	Intact cells	Human Mouse	Other cell lines HEK HeLa
Hirzel 2014 PhD Thesis	2014	Hirzel E (2014) Characterization of human bone marrow derived mesenchymal stem cells as a model for in vitro adipocytes studies. PhD Thesis 1-106.	LEAK ROUTINE OXPHOS ET	N NS	Permeabilized cells Intact cells	Human	Fat Other cell lines
Widmann 2014 Thesis	2014	Widmann M (2014) Effekte von Noradrenalin und LPS auf die mitochondriale Atmung von Alveolarmakrophagen. Thesis Universität Ulm, Medizinische Fakultät. 63 pp.	LEAK ROUTINE ET	ROX	Intact cells	Mouse	Lung;gill Other cell lines
Dickinson 2013 Thesis University of Warwick - Great Britain	2013	Dickinson A (2013) The role of mitochondrial DNA in tumorigenesis. Thesis University of Warwick - Great Britain 292pp.	LEAK ROUTINE ET	ROX	Intact cells	Human	Other cell lines
Vijgen 2013 Surg Obes Relat Dis	2013	Vijgen GH, Bouvy ND, Hoeks J, Wijers S, Schrauwen P, van Marken Lichtenbelt WD (2013) Impaired skeletal muscle mitochondrial function in morbidly obese patients is normalized one year after bariatric surgery. Surg Obes Relat Dis 9:936-41.	LEAK OXPHOS ET	N NS	Permeabilized tissue	Human	Skeletal muscle
Beaudoin 2013 Am J Physiol Regul Integr Comp Physiol	2013	Beaudoin MS, Snook LA, Arkell AM, Simpson JA, Holloway GP, Wright DC (2013) Resveratrol supplementation improves white adipose tissue function in a depot-specific manner in Zucker diabetic fatty rats. Am J Physiol Regul Integr Comp Physiol 305:542-51.	LEAK OXPHOS ET	N NS	Permeabilized cells	Rat	Fat
Gupte 2013 Endocrinology	2013	Gupte AA, Minze LJ, Reyes M, Ren Y, Wang X, Brunner G, Ghosn M, Cordero-Reyes AM, Ding K, Pratico D, Morrisett J, Shi ZZ, Hamilton DJ, Lyon CJ, Hsueh WA (2013) High fat feeding-induced hyperinsulinemia increases cardiac glucose uptake and mitochondrial function despite peripheral insulin resistance. Endocrinology 154:2650-62.	LEAK OXPHOS ET	N S ROX	Isolated mitochondria	Mouse	Heart
Karlsson 2013 Int J Biochem Cell Biol	2013	Karlsson M, Hempel C, Sjövall F, Hansson Magnus J, Kurtzhals JA, Elmér E (2013) Brain mitochondrial function in a murine model of cerebral malaria and the therapeutic effects of rhEPO. Int J Biochem Cell Biol 45:151-5.	LEAK OXPHOS ET		Homogenate	Mouse	Nervous system
Ceusters 2013 Mitochondrion	2013	Ceusters Justine D, Mouithys-Mickalad AA, Franck TJ, Derochette S, Vanderplasschen A, Deby-Dupont GP, Serteyn DA (2013) Effect of myeloperoxidase and anoxia/reoxygenation on mitochondrial respiratory function of cultured primary equine skeletal myoblasts. Mitochondrion 13:410-16.	LEAK ROUTINE OXPHOS ET		Permeabilized cells	Horse	Skeletal muscle
Pichaud 2013 J Bioenerg Biomembr	2013	Pichaud N, Ballard JWO, Tanguay RM, Blier PU (2013) Mitochondrial haplotype divergences affect specific temperature sensitivity of mitochondrial respiration. J Bioenerg Biomembr 45:25-35.	LEAK OXPHOS ET	N NS ROX	Permeabilized tissue	Hexapods	Skeletal muscle
Dickinson 2013 Cell Death Differ	2013	Dickinson A, Yeung KY, Donoghue J, Baker MJ, Kelly RDW, McKenzie M, Johns TG, St. John JC (2013) The regulation of mitochondrial DNA copy number in glioblastoma cells. Cell Death Differ 20:1644–53.	LEAK ROUTINE ET	ROX		Human	Nervous system Other cell lines
Hall 2013 Oncotarget	2013	Hall A, Meyle KD, Lange MK, Klima M, Sanderhoff M, Dahl C, Abildgaard C, Thorup K, Moghimi SM, Jensen PB, Bartek J, Guldberg P, Christensen C (2013) Dysfunctional oxidative phosphorylation makes malignant melanoma cells addicted to glycolysis driven by the (V600E)BRAF oncogene. Oncotarget 4:584-99.	LEAK OXPHOS ET	N ROX		Human	Other cell lines
Iftikar 2013 PLoS One	2013	Iftikar FI, Hickey AJ (2013) Do mitochondria limit hot fish hearts? Understanding the role of mitochondrial function with heat stress in Notolabrus celidotus. PLoS One 8:e64120.	LEAK OXPHOS ET	N CIV NS ROX	Permeabilized tissue	Fishes	Heart
Van Eunen 2013 PLoS Comput Biol	2013	van Eunen K, Simons SM, Gerding A, Bleeker A, den Besten G, Touw CM, Houten SM, Groen BK, Krab K, Reijngoud DJ, Bakker BM (2013) Biochemical competition makes fatty-acid β-oxidation vulnerable to substrate overload. PLoS Comput Biol 9:e1003186.	ET	F N	Isolated mitochondria	Rat	Liver
Hara 2013 Eur J Anaesthesiol	2013	Hara N, Karlsson M, Sjövall F, Hansson Magnus J, Elmér E, Uchino H (2013) Early brain mitochondrial dysfunction in a mouse model of sepsis: 7AP4‐9. Eur J Anaesthesiol 30,112-112.	LEAK OXPHOS ET	N S CIV NS	Homogenate	Mouse	Nervous system
Clarke 2013 Int J Biochem Cell Biol	2013	Clarke KJ, Porter RK (2013) Uncoupling protein 1 dependent reactive oxygen species production by thymus mitochondria. Int J Biochem Cell Biol 45:81-9.	LEAK ET	N S Gp	Isolated mitochondria	Rat	Islet cell;pancreas;thymus
Wredenberg 2013 PLoS Genet	2013	Wredenberg A, Lagouge M, Bratic A, Metodiev MD, Spåhr H, Mourier A, Freyer C, Ruzzenente B, Tain L, Grönke S, Baggio F, Kukat C, Kremmer E, Wibom R, Polosa PL, Habermann B, Partridge L, Park CB, Larsson NG (2013) MTERF3 regulates mitochondrial ribosome biogenesis in invertebrates and mammals. PLoS Genet 9:e1003178.	LEAK OXPHOS ET	N S Gp NS	Permeabilized tissue	Drosophila
Cavallo 2013 PLoS One	2013	Cavallo A, Priore P, Gnoni GV, Papa S, Zanotti F, Gnoni A (2013) 3,5-Diiodo-L-thyronine administration to hypothyroid rats rapidly enhances fatty acid oxidation rate and bioenergetic parameters in liver cells. PLoS One 8:e52328. doi: 10.1371/journal.pone.0052328	LEAK OXPHOS ET	F S NS	Isolated mitochondria	Rat	Liver
Viall 2013 J Autoimmun	2013	Viall CA, Chen Q, Liu B, Hickey A, Snowise S, Salmon JE, Stone PR, Chamley LW (2013) Antiphospholipid antibodies internalised by human syncytiotrophoblast cause aberrant cell death and the release of necrotic trophoblast debris. J Autoimmun 47:45-57.	LEAK OXPHOS ET	N S		Human	Genital
Karamercan 2013 Shock	2013	Karamercan MA, Weiss SL, Villarroel JP, Guan Y, Werlin E, Figueredo R, Becker LB, Sims C (2013) Can peripheral blood mononuclear cells be used as a proxy for mitochondrial dysfunction in vital organs during hemorrhagic shock and resuscitation? Shock 40:476-84.	LEAK ROUTINE OXPHOS ET	N S CIV	Intact cells Isolated mitochondria	Rat	Heart Liver Kidney Blood cells Lymphocyte
Henriques 2013 Thesis Universidade de Coimbra - Portugal	2013	Henriques TAF (2013) High-resolution respirometry for metabolic profiling of acute rat hippocampal slices. Thesis Universidade de Coimbra - Portugal 38pp.	LEAK ROUTINE ET	N S ROX	Intact cells	Rat	Nervous system
Cahill 2013 Biofouling	2013	Cahill PL, Heasman K, Hickey A, Mountfort D, Jeffs A, Kuhajek J (2013) Screening for negative effects of candidate ascidian antifoulant compounds on a target aquaculture species, Perna canaliculus Gmelin. Biofouling 29:29-37.	LEAK OXPHOS ET	N S ROX	Permeabilized tissue	Molluscs	Lung;gill
Yuzefovych 2013 Endocrinology	2013	Yuzefovych LV, Schuler AM, Chen J, Alvarez DF, Eide L, Ledoux SP, Wilson GL, Rachek LI (2013) Alteration of mitochondrial function and insulin sensitivity in primary mouse skeletal muscle cells isolated from transgenic and knockout mice: role of OGG1. Endocrinology 154:2640-9.	LEAK ET	N	Permeabilized tissue	Mouse	Skeletal muscle
Hall 2013 Biochim Biophys Acta	2013	Hall A, Larsen AK, Parhamifar L, Meyle KD, Wu LP, Moghimi SM (2013) High-resolution respirometry analysis of polyethylenimine-mediated mitochondrial energy crisis and cellular stress: Mitochondrial proton leak and inhibition of the electron transport system. Biochim Biophys Acta 1827:1213-25.	LEAK ROUTINE OXPHOS ET	N S CIV ROX	Isolated mitochondria SMP	Mouse	Liver Other cell lines
Gilliam 2013 Free Radic Biol Med	2013	Gilliam LA, Fisher-Wellman KH, Lin CT, Maples JM, Cathey BL, Neufer PD (2013) The anticancer agent doxorubicin disrupts mitochondrial energy metabolism and redox balance in skeletal muscle. Free Radic Biol Med 65:988-96.	OXPHOS ET	N S	Permeabilized tissue	Rat	Skeletal muscle
Constant-Urban 2013 Bioorg Med Chem Lett	2013	Constant-Urban C, Charif M, Goffin E, Van Heugen JC, Elmoualij B, Chiap P, Mouithys-Mickalad A, Serteyn D, Lebrun P, Pirotte B, De Tullio P (2013) Triphenylphosphonium salts of 1,2,4-benzothiadiazine 1,1-dioxides related to diazoxide targeting mitochondrial ATP-sensitive potassium channels. Bioorg Med Chem Lett 23:5878-81.	LEAK ROUTINE ET			Rat	Other cell lines
Chacko 2013 Lab Invest	2013	Chacko BK, Kramer PA, Ravi S, Johnson MS, Hardy RW, Ballinger SW, Darley-Usmar VM (2013) Methods for defining distinct bioenergetic profiles in platelets, lymphocytes, monocytes, and neutrophils, and the oxidative burst from human blood. Lab Invest 93:690-700.	LEAK ROUTINE ET	ROX	Intact cells	Human	Blood cells Other cell lines Lymphocyte Platelet
Weber 2013 Thesis East Carolina University	2013	Weber T (2013) The effect of contractile activity and substrate challenges on metabolic flexibility in human primary myotubes. Thesis East Carolina University - USA:105 pp.	LEAK OXPHOS ET	N S NS	Permeabilized cells	Human	Skeletal muscle Other cell lines
Volejnikova 2013 FEMS Yeast Res	2013	Volejníková A, Hlousková J, Sigler K, Pichová A (2013) Vital mitochondrial functions show profound changes during yeast culture ageing. FEMS Yeast Res 13:7-15.	ROUTINE ET		Isolated mitochondria Intact cells	Saccharomyces cerevisiae Fungi
Muller 2013 Exp Neurol	2013	Muller AP, Haas CB, Camacho-Pereira J, Brochier AW, Gnoatto J, Zimmer ER, de Souza DO, Galina A, Portela LV (2013) Insulin prevents mitochondrial generation of H₂O₂ in rat brain. Exp Neurol 247:66-72.	LEAK OXPHOS ET	N S		Rat	Nervous system
Smith 2013 Biochem J	2013	Smith ME, Tippetts TS, Brassfield ES, Tucker BJ, Ockey A, Swensen AC, Anthonymuthu TS, Washburn TD, Kane DA, Prince JT, Bikman BT (2013) Mitochondrial fission mediates ceramide-induced metabolic disruption in skeletal muscle. Biochem J 456:427-39.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Permeabilized tissue Intact cells	Mouse	Skeletal muscle Other cell lines
Wohlwend 2013 Thesis	2013	Wohlwend M (2013) Mitochondrial function in health and disease - high-resolution respirometry in rats inbred for high vs. low running capacity. Thesis Norwegian University of Science and Technology - Trondheim: 44pp.	LEAK OXPHOS ET	F N S NS	Permeabilized tissue	Rat	Heart Skeletal muscle
Dos Santos 2013 Bio Open	2013	Dos Santos RS, Galina A, Da-Silva WS (2013) Cold acclimation increases mitochondrial oxidative capacity without inducing mitochondrial uncoupling in goldfish white skeletal muscle. Bio Open 2:82-7.	LEAK OXPHOS ET	N S	Permeabilized tissue Isolated mitochondria	Fishes	Skeletal muscle
Ghozlan 2013 Thesis University of Calgary - Canada	2013	Ghozlan M (2013) The effect of myostatin on glucose metabolism and insulin sensitivity. Thesis University of Calgary - Canada 104pp.	LEAK ROUTINE ET		Intact cells	Mouse	Skeletal muscle Liver Other cell lines
Hagl 2013 Pharmacol Res	2013	Hagl S, Kocher A, Schiborr C, Eckert SH, Ciobanu I, Birringer M, El-Askary H, Helal A, Khayyal MT, Frank J, Muller WE, Eckert GP (2013) Rice bran extract protects from mitochondrial dysfunction in guinea pig brains. Pharmacol Res 76C:17-27.	LEAK OXPHOS ET	N S CIV NS ROX	Isolated mitochondria	Guinea pig	Nervous system
Casanova 2013 Thesis Universitat Rovira i Virgili - Spain	2013	Casanova Vallvé E (2013) Modulation of Mmuscle energy metabolism by bioactive compounds. Thesis Universitat Rovira i Virgili - Spain 117pp.	ROUTINE ET	N S NS ROX	Intact cells	Rat	Skeletal muscle
Monteiro 2013 Thesis	2013	Monteiro Siqueira C (2013) Avaliação de medicamentos homeopáticos para gripe humana por ensaios in vitro, pré-clínico e clínico. Dissertation p152.	LEAK ROUTINE ET	CIV ROX	Intact cells	Dog	Kidney Other cell lines
Chu 2013 PLoS One	2013	Chu MJ, Phillips AR, Hosking AW, Macdonald JR, Bartlett AS, Hickey AJ (2013) Hepatic mitochondrial function analysis using needle liver biopsy samples. PLoS One 8:e79097.	LEAK OXPHOS ET	N ROX	Permeabilized tissue	Human Rat	Liver
Bhattacharyya 2013 PLoS One	2013	Bhattacharyya S, Saha S, Giri K, Lanza IR, Nair KS, Jennings NB, Rodriguez-Aguayo C, Lopez-Berestein G, Basal E, Weaver AL, Visscher DW, Cliby W, Sood AK, Bhattacharya R, Mukherjee P (2013) Cystathionine Beta-Synthase (CBS) contributes to advanced ovarian cancer progression and drug resistance. PLoS One 8:e79167.	ROUTINE ET		Intact cells	Human	Genital Other cell lines
Sjövall 2013 Thesis Lund University - Sweden	2013	Sjövall F (2013) Mitochondrial function in sepsis - temporal evolvement of respiratory capacity in human blood cells. Thesis Lund University - Sweden 83pp.	LEAK ROUTINE OXPHOS ET	N S ROX	Intact cells Permeabilized cells	Human	Blood cells Platelet
Aidt 2013 PLoS Curr	2013	Aidt FH, Nielsen SM, Kanters J, Pesta D, Nielsen TT, Nørremølle A, Hasholt L, Christiansen M, Hagen CM (2013) Dysfunctional mitochondrial respiration in the striatum of the Huntington's disease transgenic R6/2 mouse model. PLoS Curr 5. pii:ecurrents.hd.d8917b4862929772c5a2f2a34ef1c201.	LEAK OXPHOS ET	N S CIV NS ROX	Homogenate	Mouse	Nervous system
Van der Laans 2013 J Clin Invest	2013	van der Lans AA, Hoeks J, Brans B, Vijgen GH, Visser MG, Vosselman MJ, Hansen J, Jörgensen JA, Wu J, Mottaghy FM, Schrauwen P, van Marken Lichtenbelt WD (2013) Cold acclimation recruits human brown fat and increases nonshivering thermogenesis. J Clin Invest 123:3395-403.	LEAK OXPHOS ET	N NS	Permeabilized tissue Isolated mitochondria	Human	Skeletal muscle
Hroudova 2013 Mitochondrion	2013	Hroudová J, Fišar Z, Kitzlerová E, Zvěřová M, Raboch J (2013) Mitochondrial respiration in blood platelets of depressive patients. Mitochondrion 13:795-800.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Permeabilized cells Intact cells	Human	Blood cells Platelet
Zeh 2013 Thesis	2013	Zeh RM (2013) Neurological and molecular biological characterisation of the mutant mouse line Tom40. Thesis Technische Universität München 243pp.	OXPHOS ET	N S ROX	Isolated mitochondria	Rat	Heart Nervous system
Hirzel 2013 J Recept Signal Transduct Res	2013	Hirzel E, Lindinger PW, Maseneni S, Giese M, Rhein VV, Eckert A, Hoch M, Krähenbühl S, Eberle AN (2013) Differential modulation of ROS signals and other mitochondrial parameters by the antioxidants MitoQ, resveratrol and curcumin in human adipocytes. J Recept Signal Transduct Res 33:304-12.	ROUTINE ET	N NS	Permeabilized cells	Human	Fat Other cell lines
Vijgen 2013 J Clin Endocrinol Metab	2013	Vijgen GH, Sparks LM, Bouvy ND, Schaart G, Hoeks J, van Marken Lichtenbelt WD, Schrauwen P (2013) Increased oxygen consumption in human adipose tissue from the "brown adipose tissue" region. J Clin Endocrinol Metab 98:E1230-4.	LEAK ROUTINE ET		Permeabilized tissue	Human	Fat
Villarroel 2013 J Trauma Acute Care Surg	2013	Villarroel JP, Guan Y, Werlin E, Selak MA, Becker LB, Sims CA (2013) Hemorrhagic shock and resuscitation are associated with peripheral blood mononuclear cell mitochondrial dysfunction and immunosuppression. J Trauma Acute Care Surg 75:24-31.	LEAK ROUTINE ET	S ROX	Intact cells	Rat	Blood cells Lymphocyte
Stride 2013 Eur J Heart Fail	2013	Stride N, Larsen S, Hey-Mogensen M, Sander K, Lund JT, Gustafsson F, Kober L, Dela F (2013) Decreased mitochondrial oxidative phosphorylation capacity in the human heart with left ventricular systolic dysfunction. Eur J Heart Fail 15:150-7.	OXPHOS ET	N S CIV NS	Permeabilized tissue	Human	Heart
Smith 2013 Thesis The University of Guelph - Canada	2013	Smith BK (2013) Investigations into the regulation of skeletal muscle mitochondrial metabolism. Thesis The University of Guelph - Canada 139pp.	LEAK OXPHOS ET	N NS ROX	Permeabilized tissue	Rat	Skeletal muscle
Martinez 2013 Marine Biol	2013	Martinez E, Menze MA, Torres JJ (2013) Mitochondrial energetics of benthic and pelagic Antarctic teleosts. Marine Biol 160:2813-23.	LEAK OXPHOS ET	N S NS	Homogenate	Fishes	Liver
Hughey 2013 Cardiovasc Diabetol	2013	Hughey CC, Ma L, James FD, Bracy DP, Wang Z, Wasserman DH, Rottman JN, Hittel DS, Shearer J (2013) Mesenchymal stem cell transplantation for the infarcted heart: therapeutic potential for insulin resistance beyond the heart. Cardiovasc Diabetol 12:128.	OXPHOS ET	N NS	Permeabilized tissue	Mouse	Heart
Li 2013 Free Radic Biol Med	2013	Li H, Kumar Sharma L, Li Y, Hu P, Idowu A, Liu Danhui, Lu J, Bai Y (2013) Comparative bioenergetic study of neuronal and muscle mitochondria during aging. Free Radic Biol Med 63:30-40.	LEAK ET	N S CIV	Intact cells	Mouse	Skeletal muscle Nervous system
Rojahn 2013 Thesis Norwegian University of Life Sciences - Ås	2013	Rojahn L (2013) Effects of micronutrients on survival and mitochondrial viability in honey bees (Apis mellifera). Thesis Norwegian University of Life Sciences - Ås: 41 pp.	OXPHOS ET	N S ROX	Permeabilized tissue	Hexapods	Skeletal muscle
Jacobs 2013 Exp Physiol	2013	Jacobs R, Boushel RC, Wright-Paradis C, Calbet JA, Robach P, Gnaiger E, Lundby C (2013) Mitochondrial function in human skeletal muscle following high altitude exposure. Exp Physiol 98:245-55.	LEAK OXPHOS ET	F N S NS	Permeabilized tissue	Human	Skeletal muscle
Strobel 2013 PLoS One	2013	Strobel A, Graeve M, Poertner HO, Mark FC (2013) Mitochondrial acclimation capacities to ocean warming and acidification are limited in the antarctic nototheniid fish, Notothenia rossii and Lepidonotothen squamifrons. PLoS One 8:e68865.	LEAK OXPHOS ET	N S NS ROX	Isolated mitochondria	Fishes	Liver
Segalés 2013 Am J Physiol Endocrinol Metab	2013	Segalés J, Paz JC, Hernández-Alvarez MI, Sala D, Muñoz JP, Noguera E, Pich S, Palacín M, Enríquez JA, Zorzano A (2013) A form of mitofusin 2 (Mfn2) lacking the transmembrane domains and the COOH-terminal end stimulates metabolism in muscle and liver cells. Am J Physiol Endocrinol Metab 305:1208-21.	LEAK ROUTINE OXPHOS ET	N	Intact cells Permeabilized tissue	Mouse	Skeletal muscle Liver Other cell lines
Goo 2013 Clin Exp Pharmacol Physiol	2013	Goo S, Pham T, Han JC, Nielsen P, Taberner A, Hickey A, Loiselle D (2013) Multiscale measurement of cardiac energetics. Clin Exp Pharmacol Physiol 40:671-81.	LEAK OXPHOS ET	N NS	Permeabilized cells Homogenate Isolated mitochondria	Rat	Heart
Schwarzkopf 2013 Pharmazie	2013	Schwarzkopf TM, Hagl S, Eckert GP, Klein J (2013) Neuroprotection by bilobalide in ischemia: improvement of mitochondrial function. Pharmazie 68:584-9.	LEAK OXPHOS ET	N S CIV ROX	Isolated mitochondria	Mouse	Nervous system
Sjoevall 2013 Mitochondrion	2013	Sjövall F, Ehinger JK, Marelsson SE, Morota S, Asander Frostner E, Uchino H, Lundgren J, Arnbjörnsson E, Hansson Magnus J, Fellman V, Elmér E (2013) Mitochondrial respiration in human viable platelets - methodology and influence of gender, age and storage. Mitochondrion 13:7-14.	LEAK ROUTINE OXPHOS ET	N ROX	Permeabilized cells Intact cells	Human	Blood cells Platelet
Schneeberger 2013 Cell	2013	Schneeberger M, Dietrich MO, Sebastián D, Imbernón M, Castaño C, Garcia A, Esteban Y, Gonzalez-Franquesa A, Rodríguez IC, Bortolozzi A, Garcia-Roves PM, Gomis R, Nogueiras R, Horvath TL, Zorzano A, Claret M (2013) Mitofusin 2 in POMC neurons connects ER stress with leptin resistance and energy imbalance. Cell 155:172-87.	LEAK OXPHOS ET	N NS ROX	Homogenate	Mouse	Nervous system
De Castro IP 2013 Cell Death Dis	2013	de Castro IP, Costa AC, Celardo I, Tufi R, Dinsdale D, Loh SH, Martins LM (2013) Drosophila ref(2)P is required for the parkin-mediated suppression of mitochondrial dysfunction in pink1 mutants. Cell Death Dis 24:e873.	LEAK OXPHOS ET	N S	Homogenate	Drosophila
Mayeur 2013 PhD Thesis	2013	Mayeur S (2013) Retard de croissance intra-utérin et vulnérabilité au syndrome métabolique: recherche de marqueurs placentaires dans un modèle de dénutrition maternelle prénatale et chez l'Homme. PhD Thesis 1-225.	LEAK OXPHOS ET	N S CIV NS ROX	Isolated mitochondria	Rat	Genital
Costa 2013 Cell Death Dis	2013	Costa AC, Loh SH, Martins LM (2013) Drosophila Trap1 protects against mitochondrial dysfunction in a PINK1/parkin model of Parkinson's disease. Cell Death Dis 4:e467.	OXPHOS ET	N S	Permeabilized tissue	Drosophila
Jacobs 2013 J Appl Physiol	2013	Jacobs R, Flück D, Bonne TC, Bürgi S, Christensen PM, Toigo M, Lundby C (2013) Improvements in exercise performance 1 with high-intensity interval training 2 coincide with an increase in skeletal muscle mitochondrial content and function. J Appl Physiol 115:785-93.	LEAK OXPHOS ET	F N S CIV NS ROX	Permeabilized tissue	Human	Skeletal muscle
Montaigne 2013 J Am Coll Cardiol	2013	Montaigne D, Marechal X, Lefebvre P, Modine T, Fayad G, Dehondt H, Hurt C, Coisne A, Koussa M, Remy-Jouet I, Zerimech F, Boulanger E, Lacroix D, Staels B, Neviere R (2013) Mitochondrial dysfunction as an arrhythmogenic substrate. J Am Coll Cardiol 62:1466-73.	LEAK OXPHOS ET	N S	Permeabilized tissue	Human	Heart
Bresciani Martins de Andrade P 2013 J Bioenerg Biomembr	2013	Bresciani Martins de Andrade P, Glaser V, da Luz Scheffer D, de Paula Ferreira PM, Wannmacher CM, Farina M, de Oliveira PA, Prediger RD, Latini A (2013) Platelet oxygen consumption as a peripheral blood marker of brain energetics in a mouse model of severe neurotoxicity. J Bioenerg Biomembr 45:449-57.	ROUTINE ET			Mouse	Blood cells Platelet
Hagenbuchner 2013 Oncogene	2013	Hagenbuchner J, Kuznetsov AV, Obexer P, Ausserlechner MJ (2013) BIRC5/Survivin enhances aerobic glycolysis and drug resistance by altered regulation of the mitochondrial fusion/fission machinery. Oncogene 32:4748-57.	OXPHOS ET	N S CIV	Permeabilized cells Intact cells	Human	Other cell lines
Pak 2013 Am J Respir Cell Mol Biol	2013	Pak O, Sommer N, Hoeres T, Bakr A, Waisbrod S, Sydykov A, Haag D, Esfandiary A, Kojonazarov B, Veit F, Fuchs B, Weisel FC, Hecker M, Schermuly RT, Grimminger F, Ghofrani HA, Seeger W, Weissmann N (2013) Mitochondrial hyperpolarization in pulmonary vascular remodeling - UCP2 deficiency as disease model. Am J Respir Cell Mol Biol 49:358-67.	LEAK ROUTINE ET	N S	Intact cells	Human Rat	Lung;gill
Stephenson 2013 Thesis Royal Melbourne Institute of Technology - Melbourne	2013	Stephenson EJ (2013) Mitochondrial function in metabolic health. Thesis Royal Melbourne Institute of Technology - Melbourne: 106pp.	LEAK OXPHOS ET	N S NS ROX	Permeabilized tissue	Rat	Skeletal muscle
Thompson 2013 J Surg Res	2013	Thompson JR, Swanson SA, Casale GP, Johanning JM, Papoutsi E, Koutakis P, Miserlis D, Zhu Z, Pipinos II (2013) Gastrocnemius mitochondrial respiration: are there any differences between men and women? J Surg Res 185:206-11.	OXPHOS ET	N S CIV	Permeabilized tissue	Human	Skeletal muscle
Sjoevall 2013 Crit Care	2013	Sjoevall F, Morota S, Persson J, Hansson Magnus J, Elmer E (2013) Patients with sepsis exhibit increased mitochondrial respiratory capacity in peripheral blood immune cells. Crit Care 17:R152.	LEAK ROUTINE OXPHOS ET	N S CIV NS ROX	Permeabilized cells Intact cells	Human	Blood cells
Perevoshchikova 2013 Free Radic Biol Med	2013	Perevoshchikova IV, Quinlan CL, Orr AL, Gerencser AA, Brand MD (2013) Sites of superoxide and hydrogen peroxide production during fatty acid oxidation in rat skeletal muscle mitochondria. Free Radic Biol Med 61:298-309. doi: 10.1016/j.freeradbiomed.2013.04.006	LEAK OXPHOS ET	F S	Isolated mitochondria	Rat	Skeletal muscle
Zhang 2013 PLoS One	2013	Zhang Z, Tsukikawa M, Peng M, Polyak E, Nakamaru-Ogiso E, Ostrovsky J, McCormack S, Place E, Clarke C, Reiner G, McCormick E, Rappaport E, Haas R, Baur JA, Falk MJ (2013) Primary respiratory chain disease causes tissue-specific dysregulation of the global transcriptome and nutrient-sensing signaling network. PLoS One 8:e69282.	LEAK ROUTINE OXPHOS ET	N	Permeabilized cells Intact cells	Human	Fibroblast
Glancy 2013 Biochemistry	2013	Glancy B, Willis WT, Chess DJ, Balaban RS (2013) Effect of calcium on the oxidative phosphorylation cascade in skeletal muscle mitochondria. Biochemistry 52:2793-809.	OXPHOS ET	N CIV	Intact organ Isolated mitochondria		Skeletal muscle
Munro 2013 Aging Cell	2013	Munro D, Pichaud N, Paquin F, Kemeid V, Blier PU (2013) Low hydrogen peroxide production in mitochondria of the long-lived Arctica islandica: underlying mechanisms for slow aging. Aging Cell 12:5845-92.	LEAK OXPHOS ET	N S CIV NS ROX	Isolated mitochondria	Molluscs	Endothelial;epithelial;mesothelial cell
Gottfried 2013 PLoS One	2013	Gottfried E, Lang SA, Renner K, Bosserhoff A, Gronwald W, Rehli M, Einhell S, Gedig I, Singer K, Seilbeck A, Mackensen A, Grauer O, Hau P, Dettmer K, Andreesen R, Oefner PJ, Kreutz M (2013) New aspects of an old drug - Diclofenac targets MYC and glucose metabolism in tumor cells. PLoS One 8:e66987.	LEAK ROUTINE ET		Intact cells	Human Mouse	Endothelial;epithelial;mesothelial cell Blood cells Other cell lines Lymphocyte
Freitas-Correa 2013 Stem Cell Res	2013	Freitas-Correa L, Lourenco MV, Acquarone M, da Costa RF, Galina A, Rehen SK, Ferreira ST (2013) 2,4-Dinitrophenol induces neural differentiation of murine embryonic stem cells. Stem Cell Res 11:1407-16.	ET		Intact cells	Mouse	Stem cells
Hernandez-Alvarez 2013 Antioxid Redox Signal	2013	Hernández-Alvarez MI, Paz JC, Sebastián D, Muñoz JP, Liesa M, Segalés J, Palacín M, Zorzano A (2013) Glucocorticoid modulation of mitochondrial function in hepatoma cells requires the mitochondrial fission protein Drp1. Antioxid Redox Signal 19:366-78.	OXPHOS ET	N S NS ROX	Homogenate	Rat	Liver Other cell lines
Dos Santos 2013 J Bioenerg Biomembr	2013	dos Santos RS, Peçanha FL, da-Silva WS (2013) Functional characterization of an uncoupling protein in goldfish white skeletal muscle. J Bioenerg Biomembr 45:243-51.	LEAK OXPHOS ET	S	Isolated mitochondria	Fishes	Skeletal muscle
Trumbeckaite 2013 Mitochondrion	2013	Trumbeckaite S, Gizatullina Z, Arandarcikaite O, Röhnert P, Vielhaber S, Malesevic M, Fischer G, Seppet E, Striggow F, Gellerich FN (2013) Oxygen glucose deprivation causes mitochondrial dysfunction in cultivated rat hippocampal slices: Protective effects of CsA, its immunosuppressive congener [D-Ser](8)CsA, the novel non-immunosuppressive cyclosporin derivative Cs9, and the NMDA receptor antagonist MK 801. Mitochondrion 13:539–47.	LEAK OXPHOS ET	N S	Homogenate	Rat	Nervous system
Hals 2013 J Diabetes Res	2013	Hals IK, Rokstad AM, Strand BL, Oberholzer J, Grill V (2013) Alginate microencapsulation of human islets does not increase susceptibility to acute hypoxia. J Diabetes Res 2013:374925.	ROUTINE ET	N ROX	Intact cells	Human	Islet cell;pancreas;thymus
Kenwood 2013 Mol Metab	2013	Kenwood BM, Weaver JL, Bajwa A, Poon IK, Byrne FL, Murrow BA, Calderone JA, Huang L, Divakaruni AS, Tomsig JL, Okabe K, Lo RH, Cameron Coleman G, Columbus L, Yan Z, Saucerman JJ, Smith JS, Holmes JW, Lynch KR, Ravichandran KS, Uchiyama S, Santos WL, Rogers GW, Okusa MD, Bayliss DA, Hoehn KL (2013) Identification of a novel mitochondrial uncoupler that does not depolarize the plasma membrane. Mol Metab 3:114-23.	ROUTINE ET		Intact organism Intact cells	Mouse
Alandijany 2013 J Neurovirol	2013	Alandijany T, Kammouni W, Roy Chowdhury SK, Fernyhough P, Jackson AC (2013) Mitochondrial dysfunction in rabies virus infection of neurons. J Neurovirol 19:537-49.	LEAK OXPHOS ET	N CIV ROX	Permeabilized cells	Rat	Nervous system
Jacobs 2013 J Gerontol A Biol Sci Med Sci	2013	Jacobs R, Diaz V, Soldini L, Haider T, Thomassen M, Nordsborg NB, Gassmann M, Lundby C (2013) Fast-twitch glycolytic skeletal muscle is predisposed to age-induced impairments in mitochondrial function. J Gerontol A Biol Sci Med Sci 68:1010-22.	LEAK OXPHOS ET	F N S NS ROX	Permeabilized tissue	Mouse	Skeletal muscle
Pichaud 2013 J Exp Biol	2013	Pichaud N, Garratt M, Ballard JWO, Brooks RC (2013) Physiological adaptations to reproduction II. Mitochondrial adjustments in livers of lactating mice. J Exp Biol 216:2889-95.	LEAK OXPHOS ET	N S NS ROX	Permeabilized tissue	Mouse	Liver
Manko 2013 Acta Physiol (Oxf)	2013	Manko BO, Manko VV (2013) Mechanisms of respiration intensification of rat pancreatic acini upon carbachol-induced Ca²⁺ release. Acta Physiol (Oxf) 208:387-99.	LEAK OXPHOS ET	N S	Permeabilized cells	Rat	Islet cell;pancreas;thymus
Perales Villarroel 2013 J Surg Res	2013	Perales Villarroel JP, Figueredo R, Guan Y, Tomaiuolo M, Karamercan MA, Welsh J, Selak MA, Becker LB, Sims C (2013) Increased platelet storage time is associated with mitochondrial dysfunction and impaired platelet function. J Surg Res 184:422-9.	ROUTINE OXPHOS ET	N S NS ROX	Permeabilized cells	Human	Blood cells Platelet
Claiborne 2013 Thesis	2013	Claiborne MS (2013) Exercice Training improves exercice capacity despite present muscle mitochondrial dysfunction in the TAZ shRNA mouse model of human barth syndrome. Master's Thesis 67pp.	LEAK OXPHOS ET	N	Isolated mitochondria	Mouse	Skeletal muscle
Kushnareva 2013 Cell Death Differ	2013	Kushnareva YE, Gerencser AA, Bossy B, Ju WK, White AD, Waggoner J, Ellisman MH, Perkins G, Bossy-Wetzel E (2013) Loss of OPA1 disturbs cellular calcium homeostasis and sensitizes for excitotoxicity. Cell Death Differ 20:353-65.	LEAK ROUTINE OXPHOS ET	N S	Intact cells Permeabilized cells	Human	Endothelial;epithelial;mesothelial cell HeLa
La Guardia 2013 Front Physiol	2013	La Guardia PG, Alberici LC, Ravagnani FG, Catharino RR, Vercesi AE (2013) Protection of rat skeletal muscle fibers by either L-carnitine or coenzyme Q₁₀ against statins toxicity mediated by mitochondrial reactive oxygen generation. Front Physiol 4:103.	LEAK OXPHOS ET	N S CIV	Permeabilized tissue	Rat	Skeletal muscle
Gomez-Duran 2012 Biochim Biophys Acta	2012	Gómez-Durán A, Pacheu-Grau D, Martínez-Romero I, López-Gallardo E, López-Pérez MJ, Montoya J, Ruiz-Pesini E (2012) Oxidative phosphorylation differences between mitochondrial DNA haplogroups modify the risk of Leber's hereditary optic neuropathy. Biochim Biophys Acta 1822:1216-22.	LEAK ROUTINE ET		Intact cells	Human	Blood cells Platelet
Thiede 2012 Biochim Biophys Acta	2012	Thiede A, Gellerich FN, Schönfeld P, Siemen D (2012) Complex effects of 17β-estradiol on mitochondrial function. Biochim Biophys Acta 1817:1747-53.	LEAK OXPHOS ET		Isolated mitochondria	Rat	Nervous system Liver
Hoeks 2012 J Cell Physiol	2012	Hoeks J, Arany Z, Phielix E, Moonen-Kornips E, Hesselink MK, Schrauwen P (2012) Enhanced lipid -but not carbohydrate- supported mitochondrial respiration in skeletal muscle of PGC-1α overexpressing mice. J Cell Physiol 227:1026-33.	LEAK OXPHOS ET	F N	Isolated mitochondria	Mouse	Skeletal muscle
Brown 2012 Am J Physiol Regul Integr Comp Physiol	2012	Brown JC, Chung DJ, Belgrave KR, Staples JF (2012) Mitochondrial metabolic suppression and reactive oxygen species production in liver and skeletal muscle of hibernating thirteen-lined ground squirrels. Am J Physiol Regul Integr Comp Physiol 302:R15-28.	LEAK OXPHOS ET	N S NS	Isolated mitochondria	Other mammals	Skeletal muscle Liver
Iglesias-Gonzalez 2012 Neurochem Res	2012	Iglesias-Gonzalez J, Sanchez-Iglesias S, Mendez-Alvarez E, Rose S, Hikima A, Jenner P, Soto-Otero R (2012) Differential toxicity of 6-hydroxydopamine in SH-SY5Y human neuroblastoma cells and rat brain mitochondria: protective role of catalase and superoxide dismutase. Neurochem Res 37:2150-60.	LEAK OXPHOS ET	N	Isolated mitochondria	Rat	Nervous system
Goo 2012 PLoS One	2012	Goo CK, Lim HY, Ho QS, Too HP, Clement MV, Wong KP (2012) PTEN/Akt signaling controls mitochondrial respiratory capacity through 4E-BP1. PLoS One 7:e45806.	LEAK ROUTINE ET	ROX	Intact cells	Mouse	Fibroblast
Usui 2012 Eur J Anaes	2012	Usui D, Isaksson M, Suzuki M, Sjovall F, Elmer E, Uchino H (2012) The influence of anesthetic agents on mitochondrial function as determined by high‐resolved respirometry of human blood cells: 9AP7‐9. Eur J Anaes 29:150.	ET	N S	Permeabilized cells	Human	Blood cells Platelet
Djafarzadeh 2012 PLoS One	2012	Djafarzadeh S, Vuda M, Takala J, Jakob SM (2012) Effect of remifentanil on mitochondrial oxygen consumption of cultured human hepatocytes. PLoS One 7:e45195.	LEAK OXPHOS ET	N S CIV	Isolated mitochondria	Human	Liver
Hughey 2012 Cell Regen (Lond)	2012	Hughey CC, Alfaro MP, Belke DD, Rottman JN, Young PP, Wasserman DH, Shearer J (2012) Increased oxygen consumption and OXPHOS potential in superhealer mesenchymal stem cells. Cell Regen (Lond) 1:3.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Intact cells Permeabilized cells	Mouse Rat	Heart Stem cells
Stephenson 2012 Am J Physiol Endocrinol Metab	2012	Stephenson EJ, Camera DM, Jenkins TA, Lee JS, Kosari S, Hawley JA, Stepto NK (2012) Skeletal muscle respiratory capacity is enhanced in rats consuming an obesogenic Western diet. Am J Physiol Endocrinol Metab 302:E1541-49.	LEAK OXPHOS ET	N S NS		Rat	Skeletal muscle
Hroudova 2012 European Psychiatry	2012	Hroudova J, Fisar Z, Korabecny J, Kuca K, Jirak R, Raboch J (2012) P-451 - changes of cellular respiration in patients with Alzheimer's disease. European Psychiatry 27:01.	LEAK OXPHOS ET	N	Permeabilized cells Intact cells	Human	Blood cells Platelet
Aoun 2012 Br J Nutr	2012	Aoun M, Feillet-Coudray C, Fouret G, Chabi B, Crouzier D, Ferreri C, Chatgilialoglu C, Wrutniak-Cabello C, Cristol JP, Carbonneau MA, Coudray C (2012) Rat liver mitochondrial membrane characteristics and mitochondrial functions are more profoundly altered by dietary lipid quantity than by dietary lipid quality: effect of different nutritional lipid patterns. Br J Nutr 107:647-59.	LEAK OXPHOS ET	NS	Isolated mitochondria	Rat	Liver
Stephenson 2012 J Appl Physiol (1985)	2012	Stephenson EJ, Stepto NK, Koch LG, Britton SL, Hawley JA (2012) Divergent skeletal muscle respiratory capacities in rats artificially selected for high and low running ability: a role for Nor1? J Appl Physiol (1985) 113:1403-12.	LEAK OXPHOS ET	F N S CIV NS Other combinations ROX	Permeabilized tissue	Rat	Skeletal muscle
Wu 2012 Cell	2012	Wu J, Boström P, Sparks LM, Ye L, Choi JH, Giang AH, Khandekar M, Virtanen KA, Nuutila P, Schaart G, Huang K, Tu H, van Marken Lichtenbelt WD, Hoeks J, Enerbäck S, Schrauwen P, Spiegelman BM (2012) Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human. Cell 150:366-76.	ROUTINE ET		Intact cells	Mouse	Fat
Correa 2012 Crit Care Med	2012	Corrêa TD, Vuda M, Blaser AR, Takala J, Djafarzadeh S, Dünser MW, Silva E, Lensch M, Wilkens L, Jakob SM (2012) Effect of treatment delay on disease severity and need for resuscitation in porcine fecal peritonitis. Crit Care Med 40:2841-9.	LEAK OXPHOS ET	N S CIV NS	Permeabilized tissue Isolated mitochondria	Pig	Heart Skeletal muscle Nervous system Liver
Lemieux 2012 J Bioenerg Biomembr	2012	Lemieux H, Warren BE (2012) An animal model to study human muscular diseases involving mitochondrial oxidative phosphorylation. J Bioenerg Biomembr 44:503-12.	LEAK OXPHOS ET		Permeabilized tissue	Other invertebrates
Silva 2012 PLOS ONE	2012	Silva da Costa L, Pereira da Silva AP, Da Poian AT, El-Bacha T (2012) Mitochondrial bioenergetic alterations in mouse neuroblastoma cells infected with Sindbis virus: implications to viral replication and neuronal death. PLoS One 7:e33871.	OXPHOS ET		Permeabilized cells	Mouse	Neuroblastoma
Jose 2012 Thesis	2012	Jose C (2012) Rôle des mitochondries dans la tumorigénèse: implications pour le traitement du cancer. PhD Thesis 272.	LEAK ROUTINE OXPHOS ET	N S	Intact cells Permeabilized cells	Human	Other cell lines HeLa
Cumero 2012 Br J Pharmacol	2012	Cumero S, Fogolari F, Domenis R, Zucchi R, Mavelli I, Contessi S (2012) F₀F₁-ATPsynthase as a molecular target of 3-Iodothyronamine. Br J Pharmacol 166:2331-47	OXPHOS ET				Heart
Duicu 2012 Rev Med Chir Soc Med Nat Iasi	2012	Duicu O, Gheorgheosu D, Mirica N, Trancota S, Cristina D, Fira-Mladinescu O, Muntean D (2012) High-resolution respirometry with multiple substrates titration in permeabilized myocardial fibers. Rev Med Chir Soc Med Nat Iasi 116:207-13.	LEAK OXPHOS ET	N S NS	Permeabilized tissue	Rat	Heart
Boushel 2012 Am J Physiol Regul Integr Comp Physiol	2012	Boushel RC, Fuentes T, Hellsten Y, Saltin B (2012) Opposing effects of nitric oxide and prostaglandin inhibition on muscle mitochondrial VO₂ during exercise . Am J Physiol Regul Integr Comp Physiol 303:94-100.	LEAK OXPHOS ET	N S NS	Permeabilized tissue	Human	Skeletal muscle
Hroudova 2012 Toxicol Lett	2012	Hroudova J, Fisar Z (2012) In vitro inhibition of mitochondrial respiratory rate by antidepressants. Toxicol Lett 213:345-52.	LEAK OXPHOS ET	N S	Isolated mitochondria	Pig	Nervous system
Freyer 2012 Nat Genet	2012	Freyer C, Cree LM, Mourier A, Stewart JB, Koolmeister C, Milenkovic D, Wai T, Floros VI, Hagström E, Chatzidaki EE, Wiesner RJ, Samuels DC, Larsson NG, Chinnery PF (2012) Variation in germline mtDNA heteroplasmy is determined prenatally but modified during subsequent transmission. Nat Genet 44:1282-5.	ET	N S	Isolated mitochondria	Mouse	Heart Liver
Kumari 2012 PLoS One	2012	Kumari S, Mehta SL, Li PA (2012) Glutamate induces mitochondrial dynamic imbalance and autophagy activation: preventive effects of selenium. PLoS One 7:e39382.	OXPHOS ET			Mouse	Nervous system Other cell lines
Oellermann 2012 J Exp Biol	2012	Oellermann M, Poertner HO, Mark FC (2012) Mitochondrial dynamics underlying thermal plasticity of cuttlefish (Sepia officinalis) hearts. J Exp Biol 215:2992-3000.	LEAK OXPHOS ET		Permeabilized tissue	Molluscs	Heart
Albertini 2012 Aging (Albany NY)	2012	Albertini E, Kozieł R, Duerr A, Neuhaus M, Jansen-Duerr P (2012) Cystathionine beta synthase modulates senescence of human endothelial cells. Aging (Albany NY) 4:664-73.	LEAK ROUTINE ET		Intact cells	Human	Endothelial;epithelial;mesothelial cell HUVEC
Pesta 2012 Methods Mol Biol	2012	Pesta D, Gnaiger E (2012) High-resolution respirometry. OXPHOS protocols for human cells and permeabilized fibers from small biopsies of human muscle. Methods Mol Biol 810:25-58. https://doi.org/10.1007/978-1-61779-382-0_3	LEAK ROUTINE OXPHOS ET	F N S NS ROX	Permeabilized cells Permeabilized tissue Intact cells	Human	Skeletal muscle Other cell lines HEK Fibroblast HUVEC
Kwak 2012 Free Radic Biol Med	2012	Kwak HB, Thalacker-Mercer A, Anderson EJ, Lin CT, Kane DA, Lee NS, Cortright RN, Bamman MM, Neufer PD (2012) Simvastatin impairs ADP-stimulated respiration and increases mitochondrial oxidative stress in primary human skeletal myotubes. Free Radic Biol Med 52:198-207.	LEAK OXPHOS ET	F N S NS	Permeabilized cells Intact cells	Human	Skeletal muscle Other cell lines
Votion 2012 PLoS One	2012	Votion DM, Gnaiger E, Lemieux H, Mouithys-Mickalad A, Serteyn D (2012) Physical fitness and mitochondrial respiratory capacity in horse skeletal muscle. PLoS One 7:e34890. https://doi.org/10.1371/journal.pone.0034890	LEAK OXPHOS ET	N S NS	Permeabilized tissue	Horse	Skeletal muscle
Moon 2012 J Biol Chem	2012	Moon SH, Jenkins CM, Kiebish MA, Sims HF, Mancuso DJ, Gross RW (2012) Genetic ablation of calcium-independent phospholipase A_2γ (iPLA_2γ) attenuates calcium-induced opening of the mitochondrial permeability transition pore and resultant cytochrome c release. J Biol Chem 287:29837-50.	LEAK OXPHOS ET	N S CIV	Isolated mitochondria	Mouse	Liver
Wuest 2012 Am J Physiol Heart Circ Physiol	2012	Wuest RC, Myers DS, Stones R, Benoist D, Robinson PA, Boyle JP, Peers C, White E, Rossiter HB (2012) Regional skeletal muscle remodeling and mitochondrial dysfunction in right ventricular heart failure. Am J Physiol Heart Circ Physiol 302: H402-H411.	LEAK OXPHOS ET	N S NS ROX	Permeabilized tissue	Rat	Skeletal muscle
Leuner 2012 Mol Neurobiol	2012	Leuner K, Schulz K, Schütt T, Pantel J, Prvulovic D, Rhein V, Savaskan E, Czech C, Eckert A, Müller WE (2012) Peripheral mitochondrial dysfunction in Alzheimer's disease: focus on lymphocytes. Mol Neurobiol 46:194-204.	LEAK OXPHOS ET	N	Permeabilized cells	Human	Blood cells Lymphocyte
Correa 2012 Mitochondrion	2012	Correa CC, Aw WC, Melvin RG, Pichaud N, Ballard JWO (2012) Mitochondrial DNA variants influence mitochondrial bioenergetics in Drosophila melanogaster. Mitochondrion 12:459-64.	LEAK OXPHOS ET	N S ROX	Permeabilized tissue Isolated mitochondria	Drosophila Hexapods	Skeletal muscle
Larsen 2012 J Physiol	2012	Larsen S, Nielsen J, Neigaard Nielsen C, Nielsen LB, Wibrand F, Stride N, Schroder HD, Boushel RC, Helge JW, Dela F, Hey-Mogensen M (2012) Biomarkers of mitochondrial content in skeletal muscle of healthy young human subjects. J Physiol 590:3349-60.	LEAK OXPHOS ET	F N S CIV NS	Permeabilized tissue	Human	Skeletal muscle
Jacobs 2012 FASEB J	2012	Jacobs R, Siebenmann C, Hug M, Toigo M, Meinild AK, Lundby C (2012) Twenty-eight days at 3454-m altitude diminishes respiratory capacity but enhances efficiency in human skeletal muscle mitochondria. FASEB J 90:5192-200.	LEAK OXPHOS ET	N S	Permeabilized tissue	Human	Skeletal muscle
De Paula Martins 2012 Thesis	2012	De Paula Martins R (2012) Altered mitochondrial ultrastructure, diminished content and energetics in the cerebral cortex from methylmercury-poisoned mice are prevented by diphenyl diselenide administration. Thesis Universidade Federal de Santa Catarina, Centro de Ciências Biológicas 104pp.	LEAK ROUTINE ET		Intact cells	Mouse	Blood cells Platelet
Hirsch 2012 PloS One	2012	Hirsch A, Hahn D, Kempná P, Hofer G, Mullis PE, Nuoffer JM, Flück CE (2012) Role of AMP-activated protein kinase on steroid hormone biosynthesis in adrenal NCI-H295R cells. PLoS One 7:e30956.	ROUTINE ET	N S NS	Intact cells Permeabilized cells	Human Pig	Other cell lines
Chowdhury 2012 Brain	2012	Chowdhury SK, Smith DR, Saleh A, Schapansky J, Marquez A, Gomes S, Akude E, Morrow D, Calcutt NA, Fernyhough P (2012) Impaired adenosine monophosphate-activated protein kinase signalling in dorsal root ganglia neurons is linked to mitochondrial dysfunction and peripheral neuropathy in diabetes. Brain 135:1751-66.	LEAK OXPHOS ET		Intact cells	Mouse Rat	Nervous system
Sugimura 2012 J Reprod Dev	2012	Sugimura S, Matoba S, Hashiyada Y, Aikawa Y, Ohtake M, Matsuda H, Kobayashi S, Konishi K, Imai K. (2012) Oxidative phosphorylation-linked respiration in individual bovine oocytes. J Reprod Dev 58:636-41.	LEAK ROUTINE ET		Intact cells	Bovines	Genital
Jacobs 2012 J Appl Physiol	2012	Jacobs R, Lundby C (2012) Mitochondria express enhanced quality as well as quantity in association with aerobic fitness across recreationally active individuals up to elite athletes. J Appl Physiol 114:344-50.	OXPHOS ET		Permeabilized tissue	Human	Skeletal muscle
Kelly 2011 Mitochondrion	2011	Kelly OM, McNamara YM, Manzke LH, Meegan MJ, Porter RK (2011) The preservation of in vivo phosphorylated and activated uncoupling protein 3 (UCP3) in isolated skeletal muscle mitochondria following administration of 3,4-methylenedioxymethamphetamine (MDMA aka ecstasy) to rats/mice. Mitochondrion. 12:110-19.	ET	S	Isolated mitochondria	Mouse Rat	Skeletal muscle Liver
Timmers 2011 Cell Metab	2011	Timmers S, Konings E, Bilet L, Houtkooper RH, van de Weijer T, Goossens GH, Hoeks J, van der Krieken S, Ryu D, Kersten S, Moonen-Kornips E, Hesselink MK, Kunz I, Schrauwen-Hinderling VB, Blaak EE, Auwerx J, Schrauwen P (2011) Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans. Cell Metab 14:612-22.	LEAK OXPHOS ET	F N NS Other combinations ROX	Permeabilized tissue	Human	Skeletal muscle
Lim 2011 PloS One	2011	Lim YA, Grimm A, Giese M, Mensah-Nyagan AG, Villafranca JE, Ittner LM, Eckert A, Götz J (2011) Inhibition of the mitochondrial enzyme ABAD restores the amyloid-β-mediated deregulation of estradiol. PloS One 6:e28887.	LEAK OXPHOS ET	N	Permeabilized cells	Human	Neuroblastoma
Pajuelo-Reguera 2011 Br J Nutr	2011	Pajuelo-Reguera D, Quesada H, Díaz S, Fernández-Iglesias A, Arola-Arnal A, Bladé C, Salvadó J, Arola L (2011) Chronic dietary supplementation of proanthocyanidins corrects the mitochondrial dysfunction of brown adipose tissue caused by diet-induced obesity in Wistar rats. Br J Nutr 28:1-9.	LEAK OXPHOS ET	F N	Isolated mitochondria	Rat	Fat
Eberhart 2011 Biochim Biophys Acta	2011	Eberhart K, Rainer J, Bindreither D, Ritter I, Gnaiger E, Kofler R, Oefner PJ, Renner K (2011) Glucocorticoid-induced alterations in mitochondrial membrane properties and respiration in childhood acute lymphoblastic leukemia. Biochim Biophys Acta 1807:719-25.	LEAK ROUTINE OXPHOS ET	N S NS	Permeabilized cells Intact cells	Human	Blood cells
Pesta 2011 Am J Physiol Regul Integr Comp Physiol	2011	Pesta D, Hoppel F, Macek C, Messner H, Faulhaber M, Kobel C, Parson W, Burtscher M, Schocke M, Gnaiger E (2011) Similar qualitative and quantitative changes of mitochondrial respiration following strength and endurance training in normoxia and hypoxia in sedentary humans. Am J Physiol Regul Integr Comp Physiol 301:R1078–87.	LEAK OXPHOS ET	F N S NS	Permeabilized tissue	Human	Skeletal muscle
Akude 2011 Diabetes	2011	Akude E, Zherebitskaya E, Chowdhury SK, Smith DR, Dobrowsky RT, Fernyhough P (2011) Diminished superoxide generation is associated with respiratory chain dysfunction and changes in the mitochondrial proteome of sensory neurons from diabetic rats. Diabetes 60:288-97.	LEAK OXPHOS ET	N CIV	Isolated mitochondria	Rat	Nervous system
Lemieux 2011 Int J Biochem Cell Biol	2011	Lemieux H, Semsroth S, Antretter H, Höfer D, Gnaiger E (2011) Mitochondrial respiratory control and early defects of oxidative phosphorylation in the failing human heart. Int J Biochem Cell Biol 43:1729–38. https://doi.org/10.1016/j.biocel.2011.08.008	LEAK OXPHOS ET	F N S CIV NS ROX	Permeabilized tissue	Human	Heart
Pecinova 2011 Mitochondrion	2011	Pecinova A, Drahota Z, Nuskova H, Pecina P, Houstek J (2011) Evaluation of basic mitochondrial functions using rat tissue homogenates. Mitochondrion 11:722-8.	LEAK OXPHOS ET	N ROX	Homogenate Isolated mitochondria	Rat	Heart Nervous system Liver Kidney
Zangl 2011 Thesis Universität Ulm - Germany	2011	Zangl Q (2011) Funktion hepatischer Mitochondrien nach Ischämie-Reperfusion und vorheriger Behandlung mit Schwefelwasserstoff im Großtierversuch. Thesis Universität Ulm - Germany 69pp.	LEAK OXPHOS ET	S NS ROX	Permeabilized cells	Pig	Liver
Jacobs 2011 J Appl Physiol	2011	Jacobs R, Rasmussen P, Siebenmann C, Díaz V, Pesta D, Gnaiger E, Nordsborg NB, Robach P, Lundby C (2011) Determinants of time trial performance and maximal incremental exercise in highly trained endurance athletes. J Appl Physiol 111:1422–30.	LEAK OXPHOS ET	F N S NS	Permeabilized tissue	Human	Skeletal muscle
Guillet 2011 FASEB J	2011	Guillet V, Gueguen N, Cartoni R, Chevrollier A, Desquiret V, Angebault C, Amati-Bonneau P, Procaccio V, Bonneau D, Martinou JC, Reynier P (2011) Bioenergetic defect associated with mKATP channel opening in a mouse model carrying a mitofusin 2 mutation. FASEB J 25:1618-27.	LEAK OXPHOS ET	N S Gp CIV ROX	Isolated mitochondria	Mouse	Nervous system
Strub 2011 FASEB J	2011	Strub GM, Paillard M, Liang J, Gomez L, Allegood JC, Hait NC, Maceyka M, Price MM, Chen Q, Simpson DC, Kordula T, Milstien S, Lesnefsky EJ, Spiegel S (2011) Sphingosine-1-phosphate produced by sphingosine kinase 2 in mitochondria interacts with prohibitin 2 to regulate Complex IV assembly and respiration. FASEB J 25:600-12.	LEAK OXPHOS ET		Isolated mitochondria Intact cells	Mouse	Heart
Anderson 2011 Am J Physiol Heart Circ Physiol	2011	Anderson EJ, Rodriguez E, Anderson CA, Thayne K, Chitwood WR, Kypson AP (2011) Increased propensity for cell death in diabetic human heart is mediated by mitochondrial-dependent pathways. Am J Physiol Heart Circ Physiol 300:H118-24.	OXPHOS ET		Permeabilized tissue	Human	Heart
Amoedo 2011 PLoS One	2011	Amoedo ND, Rodrigues MF, Pezzuto P, Galina A, da Costa RM, de Almeida FC, El-Bacha T, Rumjanek FD (2011) Energy metabolism in h460 lung cancer cells: effects of histone deacetylase inhibitors. PLoS One 6:e22264.	OXPHOS ET		Intact cells	Human	Lung;gill
Bratic 2011 PLoS Genet	2011	Bratic A, Wredenberg A, Grönke S, Stewart JB, Mourier A, Ruzzenente B, Kukat C, Wibom R, Habermann B, Partridge L, Larsson NG (2011) The bicoid stability factor controls polyadenylation and expression of specific mitochondrial mRNAs in Drosophila melanogaster. PLoS Genet 7:e1002324.	LEAK OXPHOS ET	N S Gp NS Other combinations	Permeabilized tissue	Drosophila
Smolkova 2010 J Bioenerg Biomembr	2010	Smolková K, Bellance N, Scandurra F, Génot E, Gnaiger E, Plecitá-Hlavatá L, Ježek P, Rossignol R (2010) Mitochondrial bioenergetic adaptations of breast cancer cells to aglycemia and hypoxia. https://doi.org/10.1007/s10863-009-9267-x	ROUTINE OXPHOS ET	N NS	Intact cells	Human	Fibroblast
Sjoevall 2010 Crit Care	2010	Sjoevall F, Morota S, Hansson Magnus J, Friberg H, Gnaiger E, Elmer E (2010) Temporal increase of platelet mitochondrial respiration is negatively associated with clinical outcome in patients with sepsis. Crit Care 14:R214.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Permeabilized cells Intact cells	Human	Blood cells Platelet
Baron 2010 Thesis	2010	Baron M (2010) Copy number variations of the mitochondrial DNA as potential cause of mitochondrial diseases. Thesis Rheinischen Friedrich-Wilhelms-Universitaet Bonn, Mathematisch-Naturwissenschaftlichen Fakultät, 110pp.	LEAK OXPHOS ET	N S	Permeabilized cells	Human	Endothelial;epithelial;mesothelial cell Fibroblast
Sommer 2010 Eur Respir J	2010	Sommer N, Pak O, Schörner S, Derfuss T, Krug A, Gnaiger E, Ghofrani HA, Schermuly RT, Huckstorf C, Seeger W, Grimminger F, Weissmann N (2010) Mitochondrial cytochrome redox states and respiration in acute pulmonary oxygen sensing. https://doi.org/10.1183/09031936.00013809	ROUTINE ET		Intact cells	Human	Lung;gill Endothelial;epithelial;mesothelial cell
Groeger 2010 Crit Care	2010	Groeger M, Wagner F, Baumgart K, Huber-Lang M, Knoeferl M, Georgieff M, Radermacher P, Szabo C, Calzia E (2010) Mitochondrial respiration and cytochrome c inhibition by sulfide in peritoneal macrophages in vitro: Effects of temperature and pH. Crit Care 14:P6.	ET	CIV NS	Permeabilized cells		Macrophage-derived
Hilton 2010 J Comp Physiol B	2010	Hilton Z, Clements KD, Hickey AJ (2010) Temperature sensitivity of cardiac mitochondria in intertidal and subtidal triplefin fishes. J Comp Physiol B 180:979-90.	OXPHOS LEAK ET	CIV NS ROX	Permeabilized tissue	Fishes	Heart
Votion 2010 Equine Vet J	2010	Votion DM, Fraipont A, Goachet AG, Robert C, van Erck E, Amory H, Ceusters Justine D, de la Rebière de Pouyade G, Franck T, Mouithys-Mickalad A, Niesten A, Serteyn D (2010) Alterations in mitochondrial respiratory function in response to endurance training and endurance racing. Equine Vet J 42 Suppl 38:268-74.	OXPHOS ET	N S NS	Permeabilized tissue	Horse	Skeletal muscle
Van den Berg 2010 Metabolism	2010	van den Berg SA, Nabben M, Bijland S, Voshol PJ, van Klinken JB, Havekes LM, Romijn JA, Hoeks J, Hesselink MK, Schrauwen P, van Dijk KW (2010) High levels of whole-body energy expenditure are associated with a lower coupling of skeletal muscle mitochondria in C57Bl/6 mice. Metabolism 59:1612-8.	OXPHOS ET		Isolated mitochondria	Mouse	Skeletal muscle
Aguirre 2010 Biochim Biophys Acta	2010	Aguirre E, Rodríguez-Juárez F, Bellelli A, Gnaiger E, Cadenas S (2010) Kinetic model of the inhibition of respiration by endogenous nitric oxide in intact cells. Biochim Biophys Acta 1797:557-65. https://doi.org/10.1016/j.bbabio.2010.01.033	LEAK ROUTINE ET	ROX	Intact cells Enzyme Oxidase;biochemical oxidation		HEK
Verschoor 2010 PLoS One	2010	Verschoor ML, Wilson LA, Verschoor CP, Singh G (2010) Ets-1 regulates energy metabolism in cancer cells. PLoS One 5: e13565.	LEAK OXPHOS ET		Intact cells	Human
Fernyhough 2010 Expert Rev Endocrinol Metab	2010	Fernyhough P, Roy Chowdhury SK, Schmidt RE (2010) Mitochondrial stress and the pathogenesis of diabetic neuropathy. Expert Rev Endocrinol Metab 5:39-49.	OXPHOS ET	N CIV	Isolated mitochondria	Rat	Nervous system
Dikov 2010 Exp Gerontol	2010	Dikov D, Aulbach A, Muster B, Dröse S, Jendrach M, Bereiter-Hahn J (2010) Do UCP2 and mild uncoupling improve longevity? Exp Gerontol 45:586-95.	LEAK ROUTINE ET		Intact cells		HeLa Fibroblast HUVEC
Hoeks 2010 Diabetes	2010	Hoeks J, van Herpen NA, Mensink M, Moonen-Kornips E, van Beurden D, Hesselink MK, Schrauwen P (2010) Prolonged fasting identifies skeletal muscle mitochondrial dysfunction as consequence rather than cause of human insulin resistance. Diabetes 59:2117-25.	LEAK OXPHOS ET	F N NS Other combinations	Permeabilized tissue	Human	Skeletal muscle
Lauritzen 2010 Mol Cell Biol	2010	Lauritzen KH, Moldestad O, Eide L, Carlsen H, Nesse G, Storm JF, Mansuy IM, Bergersen LH, Klungland A (2010) Mitochondrial DNA toxicity in forebrain neurons causes apoptosis, neurodegeneration, and impaired behavior. Mol Cell Biol 30:1357-67.	LEAK OXPHOS ET	N S	Isolated mitochondria	Mouse	Nervous system
Esteves 2010 J Neurochem	2010	Esteves AR, Lu J, Rodova M, Onyango I, Lezi E, Dubinsky R, Lyons KE, Pahwa R, Burns JM, Cardoso SM, Swerdlow RH (2010) Mitochondrial respiration and respiration-associated proteins in cell lines created through Parkinson's subject mitochondrial transfer. J Neurochem 113:674-82.	LEAK ROUTINE ET	N ROX	Intact cells	Human	Blood cells Platelet
Gomez-Duran 2010 Hum Mol Genet	2010	Gómez-Durán A, Pacheu-Grau D, López-Gallardo E, Díez-Sánchez C, Montoya J, López-Pérez MJ, Ruiz-Pesini E (2010) Unmasking the causes of multifactorial disorders: OXPHOS differences between mitochondrial haplogroups. Hum Mol Genet 19:3343-53.	LEAK ROUTINE ET		Intact cells	Human
Kane 2010 Free Radic Biol Med	2010	Kane DA, Anderson EJ, Price III JW, Woodlief TL, Lin C-T, Bikman BT, Cortright RN, Neufer PD (2010) Metformin selectively attenuates mitochondrial H₂O₂ emission without affecting respiratory capacity in skeletal muscle of obese rats. Free Radic Biol Med 49:1082–7.	LEAK OXPHOS ET			Rat	Skeletal muscle
Guitart 2010 J Biol Chem	2010	Guitart T, Leon Bernardo T, Sagalés J, Stratmann T, Bernués J, Ribas de Pouplana L (2010) New aminoacyl-tRNA synthetase-like protein in insecta with an essential mitochondrial function. J Biol Chem 285:38157-66.	LEAK OXPHOS ET	N S NS	Permeabilized tissue	Drosophila Hexapods
Kotarsky 2010 Mitochondrion	2010	Kotarsky H, Karikoski R, Mörgelin M, Marjavaara S, Bergman P, Zhang DL, Smet J, van Coster R, Fellman V (2010) Characterization of complex III deficiency and liver dysfunction in GRACILE syndrome caused by a BCS1L mutation. Mitochondrion 10:497-509.	LEAK OXPHOS ET		Intact cells	Human	Fibroblast
Hansson 2010 J Biol Chem	2010	Hansson Magnus J, Morota S, Teilum M, Mattiasson G, Uchino H, Elmer E (2010) Increased potassium conductance of brain mitochondria induces resistance to permeability transition by enhancing matrix volume. J Biol Chem 285:741-50.	LEAK OXPHOS ET		Isolated mitochondria	Rat	Nervous system
Pichaud 2010 J Exp Biol	2010	Pichaud N, Chatelain EH, Ballard JWO, Tanguay R, Morrow G, Blier PU (2010)Thermal sensitivity of mitochondrial metabolism in two distinct mitotypes of Drosophila simulans: Evaluation of mitochondrial plasticity. J Exp Biol 213:1665-75.	OXPHOS ET	N Gp	Isolated mitochondria	Drosophila	Skeletal muscle
Scandurra 2010 Adv Exp Med Biol	2010	Scandurra FM, Gnaiger E (2010) Cell respiration under hypoxia: facts and artefacts in mitochondrial oxygen kinetics. https://doi.org/10.1007/978-1-4419-1241-1_2	LEAK ROUTINE OXPHOS ET		Isolated mitochondria Intact cells	Mouse	Blood cells
Remels 2010 Mol Cell Endocrinol	2010	Remels AH, Langen RC, Schrauwen P, Schaart G, Schols AM, Gosker HR (2010) Regulation of mitochondrial biogenesis during myogenesis. Mol Cell Endocrinol 315:113-20.	ROUTINE OXPHOS ET	F	Permeabilized cells	Mouse Rat	Skeletal muscle Other cell lines
Anderson 2009 J Clin Invest	2009	Anderson EJ, Lustig ME, Boyle KE, Woodlief TL, Kane DA, Lin C-T, Price JW, Kang L, Rabinovitch PS, Szeto HH, Houmard JA, Cortright RN, Wasserman DH, Neufer PD (2009) Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans. J Clin Invest 119:573-81.	OXPHOS ET		Permeabilized tissue	Human Mouse Rat	Skeletal muscle
Keeney 2009 Hum Gene Ther	2009	Keeney PM, Quigley CK, Dunham LD, Papageorge CM, Iyer S, Thomas RR, Schwarz KM, Trimmer PA, Khan SM, Portell FR, Bergquist KE, Bennett JP (2009) Mitochondrial gene therapy augments mitochondrial physiology in a Parkinson's disease cell model. Hum Gene Ther 20:897-907.	OXPHOS LEAK ROUTINE ET	ROX	Intact cells	Human	Nervous system Neuroblastoma
Pereira 2009 Biochem J	2009	Pereira da Silva AP, El-Bacha T, Kyaw N, dos Santos RS, Da Silva WS, Almeida FC, Da Poian AT, Galina A (2009) Inhibition of energy-producing pathways of HepG2 cells by 3-bromopyruvate. Biochem J 417:717-26.	LEAK ROUTINE OXPHOS ET	S ROX	Permeabilized cells Intact cells	Human	Liver
Kwon 2009 Thesis	2009	Kwon OS (2009) Effect of acute exercise or fasting on mitochondrial function and high fat diet-induced insulin resistance. PhD Thesis 46.	LEAK OXPHOS ET	F N NS	Permeabilized tissue	Rat	Skeletal muscle
Rhein 2009 Proc Natl Acad Sci U S A	2009	Rhein V, Song X, Wiesner A, Ittner LM, Baysang G, Meier F, Ozmen L, Bluethmann H, Dröse S, Brandt U, Savaskan E, Czech C, Götz J, Eckert A (2009) Amyloid-beta and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice. Proc Natl Acad Sci U S A 106:20057-62.	LEAK OXPHOS ET	N CIV ROX	Isolated mitochondria	Mouse	Nervous system
Eberhart 2009 Leukemia	2009	Eberhart K, Renner K, Ritter I, Kastenberger M, Singer K, Hellerbrand C, Kreutz M, Kofler R, Oefner PJ (2009) Low doses of 2-deoxy-glucose sensitize acute lymphoblastic leukemia cells to glucocorticoid-induced apoptosis. Leukemia 23:2167-70.	LEAK ROUTINE ET	ROX	Intact cells	Human	Blood cells Lymphocyte
Samper 2009 Free Radic Biol Med	2009	Samper E, Morgado L, Estrada JC, Bernad A, Hubbard A, Cadenas S, Melov S (2009) Increase in mitochondrial biogenesis, oxidative stress, and glycolysis in murine lymphomas. Free Radic Biol Med 46:387-96.	OXPHOS ET
Lim 2009 PlosOne	2009	Lim S, Ahn SY, Song IC, Chung MH, Jang HC, Park KS, Lee KU, Pak YK, Lee HK (2009) Chronic exposure to the herbicide, atrazine, causes mitochondrial dysfunction and insulin resistance. PLoS One 4:e5186.	OXPHOS ET		Isolated mitochondria	Rat	Skeletal muscle Liver
Vajda 2009 FEBS J	2009	Vajda S, Mándi M, Konràd C, Kiss G, Ambrus A, Adam-Vizi V, Chinopoulos C (2009) A re-evaluation of the role of matrix acidification in uncoupler-induced Ca²⁺ release from mitochondria. FEBS J 276:2713-24.	ET		Isolated mitochondria	Rat	Liver
Plecita-Hlavata 2009 Int J Biochem Cell Biol	2009	Plecita-Hlavata L, Jezek J, Jezek P (2009) Pro-oxidant mitochondrial matrix-targeted ubiquinone MitoQ₁₀ acts as anti-oxidant at retarded electron transport or proton pumping within Complex I. Int J Biochem Cell Biol 41:1697-707.	LEAK OXPHOS ROUTINE ET	S NS	Isolated mitochondria Intact cells	Rat Human	Liver Other cell lines
Flamment 2009 Am J Physiol Endocrinol Metab	2009	Flamment M, Gueguen N, Wetterwald C, Simard G, Malthièry Y, Ducluzeau PH (2009) Effects of the cannabinoid CB1 antagonist rimonabant on hepatic mitochondrial function in rats fed a high-fat diet. Am J Physiol Endocrinol Metab 297:E1162-70.	LEAK OXPHOS ET	F N S CIV	Isolated mitochondria	Rat	Liver
Tahara 2009 Free Radic Biol Med	2009	Tahara EB, Navarete FD, Kowaltowski AJ (2009) Tissue-, substrate-, and site-specific characteristics of mitochondrial reactive oxygen species generation. Free Radic Biol Med 46:1283-97.	LEAK ET OXPHOS	F N NS ROX S Gp	Isolated mitochondria	Rat	Heart Skeletal muscle Nervous system Liver Kidney
Ahting 2009 Biochim Biophys Acta	2009	Ahting U, Floss T, Uez N, Schneider-Lohmar I, Becker L, Kling E, Iuso A, Bender A, de Angelis MH, Gailus-Durner V, Fuchs H, Meitinger T, Wurst W, Prokisch H, Klopstock T (2009) Neurological phenotype and reduced lifespan in heterozygous Tim23 knockout mice, the first mouse model of defective mitochondrial import. Biochim Biophys Acta 1787:371-76.	OXPHOS ET	N S	Permeabilized cells	Mouse	Stem cells
Holmuhamedov 2009 Arch Biochem Biophys	2009	Holmuhamedov E, Lemasters JJ (2009) Ethanol exposure decreases mitochondrial outer membrane permeability in cultured rat hepatocytes. Arch Biochem Biophys 481:226-33. https://doi.org/10.1016/j.abb.2008.10.036	OXPHOS ET	S	Permeabilized cells		Liver
Anderson 2009 J Am Coll Cardiol	2009	Anderson EJ, Kypson AP, Rodriguez E, Anderson CA, Lehr EJ, Neufer PD (2009) Substrate-specific derangements in mitochondrial metabolism and redox balance in the atrium of the type 2 diabetic human heart. J Am Coll Cardiol 54:1891-8.	OXPHOS ET		Permeabilized tissue	Human	Heart
Menna-Barreto 2009 Free Radic Biol Med	2009	Menna-Barreto RF, Goncalves RL, Costa EM, Silva RS, Pinto AV, Oliveira MF, de Castro SL (2009) The effects on Trypanosoma cruzi of novel synthetic naphthoquinones are mediated by mitochondrial dysfunction. Free Radic Biol Med 47:644-53.	OXPHOS ET			Protists
Gnaiger 2009 Int J Biochem Cell Biol	2009	Gnaiger E (2009) Capacity of oxidative phosphorylation in human skeletal muscle. New perspectives of mitochondrial physiology. Int J Biochem Cell Biol 41:1837-45. https://doi.org/10.1016/j.biocel.2009.03.013	LEAK OXPHOS ET	N S NS	Permeabilized tissue Isolated mitochondria	Human Mouse	Skeletal muscle
Spacek 2008 Int J Biochem Cell Biol	2008	Spacek T, Santorová J, Zacharovová K, Berková Z, Hlavatá L, Saudek F, Jezek P (2008) Glucose-stimulated insulin secretion of insulinoma INS-1E cells is associated with elevation of both respiration and mitochondrial membrane potential. Int J Biochem Cell Biol 40:1522-35.	LEAK ROUTINE ET	ROX	Intact cells	Rat	Islet cell;pancreas;thymus Other cell lines
Phielix 2008 Physiol Behav	2008	Phielix E, Mensink M (2008) Type 2 diabetes mellitus and skeletal muscle metabolic function. Physiol Behav 94:252-8.	OXPHOS ET				Skeletal muscle
Gnaiger 2008 POS	2008	Gnaiger E (2008) Polarographic oxygen sensors, the oxygraph and high-resolution respirometry to assess mitochondrial function. In: Mitochondrial dysfunction in drug-induced toxicity (Dykens JA, Will Y, eds) John Wiley & Sons, Inc, Hoboken, NJ:327-52.	LEAK ROUTINE ET	ROX	Permeabilized cells Permeabilized tissue Intact cells	Mouse	Blood cells
Aragones 2008 Nat Genet	2008	Aragonés J, Schneider M, Van Geyte K, Fraisl P, Dresselaers T, Mazzone M, Dirkx R, Zacchigna S, Lemieux H, Jeoung NH, Lambrechts D, Bishop T, Lafuste P, Diez-Juan A, K Harten S, Van Noten P, De Bock K, Willam C, Tjwa M, Grosfeld A, Navet R, Moons L, Vandendriessche T, Deroose C, Wijeyekoon B, Nuyts J, Jordan B, Silasi-Mansat R, Lupu F, Dewerchin M, Pugh C, Salmon P, Mortelmans L, Gallez B, Gorus F, Buyse J, Sluse F, Harris RA, Gnaiger Erich, Hespel P, Van Hecke P, Schuit F, Van Veldhoven P, Ratcliffe P, Baes M, Maxwell P, Carmeliet P (2008) Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism. Nat Genet 40:170-80.	LEAK OXPHOS ET	N S NS	Permeabilized tissue	Mouse	Skeletal muscle
Arruda 2008 Endocrinology	2008	Arruda AP, Ketzer LA, Nigro M, Galina A, Carvalho DP, de Meis L (2008) Cold tolerance in hypothyroid rabbits: role of skeletal muscle mitochondria and sarcoplasmic reticulum Ca2+ ATPase isoform 1 heat production. Endocrinology 149:6262-71.	OXPHOS ET			Rabbit	Skeletal muscle
Hansson 2008 Free Radic Biol Med	2008	Hansson Magnus J, Månsson R, Morota S, Uchino H, Kallur T, Sumi T, Ishii N, Shimazu M, Keep MF, Jegorov A, Elmér E (2008) Calcium-induced generation of reactive oxygen species in brain mitochondria is mediated by permeability transition. Free Radic Biol Med 45:284-94.	LEAK OXPHOS ET		Isolated mitochondria	Rat	Nervous system Liver
Saillan-Barreau 2008 J Acquir Immune Defic Syndr	2008	Saillan-Barreau C, Tabbakh O, Chavoin JP, Casteilla L, Pénicaud L (2008) Drug-specific effect of nelfinavir and stavudine on primary culture of human preadipocytes. J Acquir Immune Defic Syndr 48:20-5.	ET		Isolated mitochondria	Human	Fat
Rosca 2008 Cardiovasc Res	2008	Rosca MG, Vazquez EJ, Kerner J, Parland W, Chandler MP, Stanley W, Sabbah HN, Hoppel CL (2008) Cardiac mitochondria in heart failure: decrease in respirasomes and oxidative phosphorylation. Cardiovasc Res 80:30-39.	LEAK OXPHOS ET	N S CIV NS	Isolated mitochondria	Dog	Heart
Hoeks 2008 FEBS Lett	2008	Hoeks J, Briedé JJ, de Vogel J, Schaart G, Nabben M, Moonen-Kornips E, Hesselink MK, Schrauwen P (2008) Mitochondrial function, content and ROS production in rat skeletal muscle: Effect of high-fat feeding. FEBS Lett 582:510-16.	ROUTINE OXPHOS ET	F NS ROX	Isolated mitochondria	Rat	Skeletal muscle
Liem 2008 Transl Res	2008	Liem D, Manintveld O, Schoonderwoerd K, McFalls E, Heinen A, Verdouw P, Sluiter W, Duncker D (2008) Ischemic preconditioning modulates mitochondrial respiration, irrespective of the employed signal transduction pathway. Transl Res 151:17-26.	OXPHOS ET		Isolated mitochondria	Rat	Heart
Cannon 2008 Methods Mol Biol	2008	Cannon B, Nedergaard J (2008) Studies of thermogenesis and mitochondrial function in adipose tissues. Methods Mol Biol 456:109-21.	OXPHOS LEAK ET	N	Isolated mitochondria		Endothelial;epithelial;mesothelial cell
Schober 2007 Theriogenology	2007	Schober D, Aurich C, Nohl H, Gille L (2007) Influence of cryopreservation on mitochondrial functions in equine spermatozoa. Theriogenology 68:745-54.	ROUTINE ET		Intact cells	Horse	Genital
Wu 2007 Am J Physiol Cell Physiol	2007	Wu M, Neilson A, Swift AL, Moran R, Tamagnine J, Parslow D, Armistead S, Lemire K, Orrell J, Teich J, Chomicz S, Ferrick DA (2007) Multiparameter metabolic analysis reveals a close link between attenuated mitochondrial bioenergetic function and enhanced glycolysis dependency in human tumor cells. https://doi.org/10.1152/ajpcell.00247.2006	LEAK ROUTINE ET	ROX	Intact cells	Human
Lou 2007 Biochem J	2007	Lou PH, Hansen BS, Olsen PH, Tullin S, Murphy MP, Brand MD (2007) Mitochondrial uncouplers with an extraordinary dynamic range. Biochem J 407:129-40.	LEAK ET		Intact cells Isolated mitochondria	Rat	Skeletal muscle Liver Islet cell;pancreas;thymus
Boushel 2007 Diabetologia	2007	Boushel RC, Gnaiger E, Schjerling P, Skovbro M, Kraunsoee R, Dela F (2007) Patients with Type 2 diabetes have normal mitochondrial function in skeletal muscle. Diabetologia 50:790-6.	LEAK OXPHOS ET	N S NS	Permeabilized tissue	Human	Skeletal muscle
Stephenne 2007 Cell Transplant	2007	Stéphenne X, Najimi M, Ngoc DK, Smets F, Hue L, Guigas B, Sokal EM (2007) Cryopreservation of human hepatocytes alters the mitochondrial respiratory chain complex 1. Cell Transplant 16:409-19.	ROUTINE ET	N	Intact cells Permeabilized cells	Human Mouse	Liver
El-Bacha 2007 Biochim Biophys Acta	2007	El-Bacha T, Midlej V, Pereira da Silva AP, Silva da Costa L, Benchimol M, Galina A, Da Poian AT (2007) Mitochondrial and bioenergetic dysfunction in human hepatic cells infected with dengue 2 virus. Biochim Biophys Acta 1772:1158-66.	LEAK ROUTINE OXPHOS ET	N S ROX	Permeabilized cells Intact cells	Human	Liver
Deschauer 2006 Mol Genet Metab	2006	Deschauer M, Gizatullina Z, Schulze A, Pritsch M, Knöppel C, Knape M, Zierz S, Gellerich FN (2006) Molecular and biochemical investigations in fumarase deficiency. Mol Genet Metab 88:146-52.	LEAK OXPHOS ET	N S ROX	Permeabilized cells Intact cells	Human	Fibroblast
Nukala 2006 J Neurosci Methods	2006	Nukala VN, Singh IN, Davis LM, Sullivan PG (2006) Cryopreservation of brain mitochondria: A novel methodology for functional studies. J Neurosci Methods 152:48-54.	LEAK OXPHOS ET	N NS	Isolated mitochondria	Rat	Nervous system
Blakely 2006 Pediatr Res	2006	Blakely EL, Rennie KJ, Jones L, Elstner M, Chrzanowska-Lightowlers ZMA, White CB, Shield JPH, Pilz DT, Turnbull DM, Poulton J, Taylor RW (2006) Sporadic intragenic inversion of the mitochondrial DNA MTND1 gene causing fatal infantile lactic acidosis. Pediatr Res 59:440-4.	OXPHOS ET			Human	Fibroblast
Safiulina 2006 Toxicol Sci	2006	Safiulina D, Peet N, Seppet E, Zharkovsky A, Kaasik A (2006) Dehydroepiandrosterone inhibits Complex I of the mitochondrial respiratory chain and is neurotoxic in vitro and in vivo at high concentrations. Toxicol Sci 93:348-56.	OXPHOS ET	N	Isolated mitochondria	Rat	Nervous system
Stadlmann 2006 Cell Biochem Biophys	2006	Stadlmann S, Renner K, Pollheimer J, Moser PL, Zeimet AG, Offner FA, Gnaiger E (2006) Preserved coupling of oxidative phosphorylation but decreased mitochondrial respiratory capacity in IL-1ß treated human peritoneal mesothelial cells. Cell Biochem Biophys 44:179-86.	ROUTINE ET		Intact cells	Human	Endothelial;epithelial;mesothelial cell
David 2005 J Biol Chem	2005	David DC, Hauptmann S, Scherping I, Schuessel K, Keil U, Rizzu P, Ravid R, Dröse S, Brandt U, Muller WE, Eckert A, Götz J (2005) Proteomic and functional analysis reveal a mitochondrial dysfunction in P301L tau transgenic mice. J Biol Chem 280:23802-14.	OXPHOS ET		Isolated mitochondria	Mouse	Nervous system
Zacharovova 2005 Transplant Proc	2005	Zacharovova K, Berkova Z, Spacek T, Kriz J, Dovolilova E, Girman P, Koblas T, Jezek P, Saudek F (2005) In vitro assessment of pancreatic islet vitality by oxymetry. Transplant Proc 37:3454-6.	OXPHOS ET			Rat	Islet cell;pancreas;thymus
Toleikis 2005 Biosci Rep	2005	Toleikis A, Trumbeckaite S, Majiene D (2005) Cytochrome C effect on respiration of heart mitochondria: influence of various factors. Biosci Rep 25:387-97.	LEAK OXPHOS ET	F N S	Permeabilized tissue Isolated mitochondria	Human Rat Rabbit	Heart
Chowdhury 2005 Biochem Biophys Res Comm	2005	Chowdhury SK, Gemin A, Singh G (2005) High activity of mitochondrial glycerophosphate dehydrogenase and glycerophosphate-dependent ROS production in prostate cancer cell lines. Biochem Biophys Res Comm 333:1139-45.	LEAK OXPHOS ET	Gp	Permeabilized cells	Human	Genital
Anmann 2005 FEBS J	2005	Anmann T, Eimre M, Kuznetsov AV, Andrienko T, Kaambre T, Sikk P, Seppet E, Tiivel T, Vendelin M, Seppet EK, Saks VA (2005) Calcium-induced contraction of sarcomeres changes the regulation of mitochondrial respiration in permeabilized cardiac cells. FEBS J 272:3145-61.	OXPHOS ET		Permeabilized cells Permeabilized tissue	Rat	Heart
Huetter 2004 Biochem J	2004	Hütter E, Renner K, Pfister G, Stöckl P, Jansen-Dürr P, Gnaiger E (2004) Senescence-associated changes in respiration and oxidative phosphorylation in primary human fibroblasts. https://doi.org/10.1042/BJ20040095	LEAK ROUTINE ET		Intact cells	Human	Fibroblast
Greco 2003 FASEB J	2003	Greco M, Villani G, Mazzucchelli F, Bresolin N, Papa S, Attardi G (2003) Marked aging-related decline in efficiency of oxidative phosphorylation in human skin fibroblasts. FASEB J 17:1706-8.	LEAK ROUTINE OXPHOS ET	N CIV	Permeabilized cells Intact cells		Fibroblast
Renner 2003 Biochim Biophys Acta	2003	Renner K, Amberger A, Konwalinka G, Gnaiger E (2003) Changes of mitochondrial respiration, mitochondrial content and cell size after induction of apoptosis in leukemia cells. Biochim Biophys Acta 1642:115-23.	ROUTINE ET		Permeabilized cells Enzyme Oxidase;biochemical oxidation Intact cells	Human	Blood cells
Appaix 2003 Exp Physiol	2003	Appaix F, Kuznetsov AV, Usson Y, Kay L, Andrienko T, Olivares J, Kaambre T, Sikk P, Margreiter R, Saks V (2003) Possible role of cytoskeleton in intracellular arrangement and regulation of mitochondria. Exp Physiol 88:175-90.	OXPHOS ET		Permeabilized cells Isolated mitochondria	Rat	Heart Skeletal muscle
Pecina 2003 Biochim Biophys Acta	2003	Pecina P, Capkova M, Chowdhury SK, Drahota Z, Dubot A, Vojtiskova A, Hansikova H, Houstekova H, Zeman J, Godinot C, Houstek J (2003) Functional alteration of cytochrome c oxidase by SURF1 mutations in Leigh syndrome. Biochim Biophys Acta 1639:53-63.	LEAK OXPHOS ET	S CIV	Intact cells Permeabilized cells	Human	Endothelial;epithelial;mesothelial cell Fibroblast
Vrbacky 2003 Physiol Res	2003	Vrbacký M, Krijt J, Drahota Z, Mĕlková Z (2003) Inhibitory effects of Bcl-2 on mitochondrial respiration. Physiol Res 52:545-54.	ROUTINE OXPHOS ET	N S	Intact cells Permeabilized cells	Human Other mammals	Endothelial;epithelial;mesothelial cell Other cell lines HeLa
Rasmussen 2001 Am J Physiol Endocrinol Metab	2001	Rasmussen UF, Rasmussen HN, Krustrup P, Quistorff B, Saltin B, Bangsbo J (2001) Aerobic metabolism of human quadriceps muscle: in vivo data parallel measurements on isolated mitochondria. Am J Physiol Endocrinol Metab 280:E301-7.	LEAK OXPHOS ET	F N S Gp NS	Isolated mitochondria	Human	Skeletal muscle
Aguilaniu 2001 J Biol Chem	2001	Aguilaniu H, Gustafsson L, Rigoulet M, Nyström T (2001) Protein oxidation in G0 cells of Saccharomyces cerevisiae depends on the state rather than rate of respiration and is enhanced in pos9 but not yap1 mutants. J Biol Chem 276:35396-404.	OXPHOS ET			Saccharomyces cerevisiae Fungi
Appaix 2000 Biochim Biophys Acta	2000	Appaix F, Minatchy M-N, Riva-Lavieille C, Olivares J, Antonsson B, Saks VA (2000) Rapid spectrophotometric method for quantitation of cytochrome c release from isolated mitochondria or permeabilized cells revisited. Biochim Biophys Acta 1457:175-81.	OXPHOS ET		Permeabilized tissue Isolated mitochondria		Heart
Du 1999 Free Radic Biol Med	1999	Du G, Willet K, Mouithys-Mickalad A, Sluse-Goffart CM, Droy-Lefaix M-T, Sluse FE (1999) EGb 761 protects liver mitochondria against injury induced by in vitro anoxia/reoxygenation. Free Radic Biol Med 27:596-604.	OXPHOS ET		Isolated mitochondria	Rat	Liver
Gnaiger 1998 Biochim Biophys Acta	1998	Gnaiger E, Lassnig B, Kuznetsov AV, Margreiter R (1998) Mitochondrial respiration in the low oxygen environment of the cell: Effect of ADP on oxygen kinetics. Biochim Biophys Acta 1365:249-54. https://doi.org/10.1016/S0005-2728(98)00076-0	LEAK OXPHOS ET	N S CIV	Isolated mitochondria	Rat	Heart Liver
Villani 1998 J Biol Chem	1998	Villani G, Greco M, Papa S, Attardi G (1998) Low reserve of cytochrome c oxidase capacity in vivo in the respiratory chain of a variety of human cell types. J Biol Chem 273:31829-36.	ROUTINE ET	N S	Intact cells Permeabilized cells		Other cell lines Platelet
Skulachev 1998 Biochim Biophys Acta	1998	Skulachev VP (1998) Uncoupling: new approaches to an old problem of bioenergetics. Biochim Biophys Acta 1363:100-124.	LEAK ET		Isolated mitochondria
Du 1998 Free Radic Biol Med	1998	Du G, Mouithys-Mickalad A, Sluse FE (1998) Generation of superoxide anion by mitochondria and impairment of their functions during anoxia and reoxygenation. Free Radic Biol Med 25:1066-74.	OXPHOS ET
Steinlechner-Maran 1997 Transplantation	1997	Steinlechner-Maran R, Eberl T, Kunc M, Schröcksnadel H, Margreiter R, Gnaiger E (1997) Respiratory defect as an early event in preservation/reoxygenation injury in endothelial cells. Transplantation 63:136-42.	ROUTINE ET	ROX	Intact cells	Human	Endothelial;epithelial;mesothelial cell HUVEC
Devin 1997 Biochim Biophys Acta	1997	Devin A, Guerin B, Rigoulet M (1997) Control of oxidative phosphorylation in rat liver mitochondria: effect of ionic media. Biochim Biophys Acta 1319:293-300.	LEAK OXPHOS ET	N	Isolated mitochondria	Rat	Liver
Villani 1997 Proc Natl Acad Sci U S A	1997	Villani G, Attardi G (1997) In vivo control of respiration by cytochrome c oxidase in wild-type and mitochondrial DNA mutation-carrying human cells. Proc Natl Acad Sci U S A 94:1166-71.	ROUTINE ET OXPHOS	N S Gp ROX	Intact cells Permeabilized cells	Human	Fibroblast
Halangk 1997 Zentralbl Chir	1997	Halangk W, Matthias R, Nedelev B, Schild L, Meyer F, Schulz H-U, Lippert H (1997) Beeinträchtigung der Energiebereitstellung von Pankreasmitochondrien bei experimenteller akuter Pankreatitis. Zentralbl Chir 122:305-8.	OXPHOS ET
Steinlechner-Maran 1996 Am J Physiol Cell Physiol	1996	Steinlechner-Maran R, Eberl T, Kunc M, Margreiter R, Gnaiger E (1996) Oxygen dependence of respiration in coupled and uncoupled endothelial cells. Am J Physiol Cell Physiol 271:C2053-61. https://doi.org/10.1152/ajpcell.1996.271.6.C2053	ROUTINE ET		Intact cells	Human	Endothelial;epithelial;mesothelial cell HUVEC
Eberl 1994 BTK-288	1994	Eberl T, Steinlechner R, Salvenmoser W, Abendstein B, Rhomberg M, Schröcksnadel H, Schmid T, Gnaiger E, Margreiter R (1994) Endothelial cell cultures as a model for organ preservation studies. In: What is Controlling Life? (Gnaiger E, Gellerich FN, Wyss M, eds) Modern Trends in BioThermoKinetics 3. Innsbruck Univ Press:288-93.	ROUTINE ET		Intact cells	Human	Endothelial;epithelial;mesothelial cell HUVEC
SteinlechnerMaran 1994 BTK-283	1994	Steinlechner-Maran R, Eberl T, Margreiter R, Gnaiger E (1994) Oxygen dependence of cellular respiration in endothelial cells: A sensitive toxicological test. In: What is Controlling Life? (Gnaiger E, Gellerich FN, Wyss M, eds) Modern Trends in BioThermo-Kinetics 3. Innsbruck Univ Press:283-7.	ROUTINE ET		Intact cells	Human	Endothelial;epithelial;mesothelial cell HUVEC
Halestrap 1986 Biochem J	1986	Halestrap AP, Dunlop JL (1986) Intramitochondrial regulation of fatty acid beta-oxidation occurs between flavoprotein and ubiquinone. A role for changes in the matrix volume. Biochem J 239:559-65. https://doi.org/10.1042/bj2390559	LEAK OXPHOS ET	F N S DQ	Isolated mitochondria	Rat	Liver
Boveris 1973 Biochem J	1973	Boveris A, Chance B (1973) The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen. Biochem J 134:707-16.	LEAK OXPHOS ET	F N S NS	Isolated mitochondria	Rat Birds	Heart
Grav 1970 Eur J Biochem	1970	Grav HJ, Pedersen JI, Christiansen EN (1970) Conditions in vitro which affect respiratory control and capacity for respiration-linked phosphorylation in brown adipose tissue mitochondria. Eur J Biochem 12:11-23.	LEAK OXPHOS ET	N S	Isolated mitochondria	Guinea pig	Fat
Klingenberg 1970 Eur J Biochem	1970	Klingenberg M (1970) Localization of the glycerol-phosphate dehydrogenase in the outer phase of the mitochondrial inner membrane. Eur J Biochem 13:247-52.	ET	Gp	Isolated mitochondria
Tuena 1969 Eur J Biochem	1969	Tuena M, Gómez-Puyou A, Peña A, Chávez E, Sandoval F (1969) Effect of ATP on the oxidation of succinate in rat brain mitochondria. Eur J Biochem 11:283-90.	ET	S	Isolated mitochondria	Rat	Nervous system
Chance 1962 J Biol Chem	1962	Chance B, Hagihara B (1962) Activation and inhibition of succinate oxidation following adenosine diphosphate supplements to pigeon heart mitochondria. J Biol Chem 237:3540-5.	LEAK OXPHOS ET	S NS	Isolated mitochondria	Birds	Heart
Hatefi 1962 J Biol Chem-XLI	1962	Hatefi Y, Haavik AG, Griffiths DE (1962) Studies on the electron transfer system. XLI. Reduced coenzyme Q (QH2)-cytochrome c reductase. J Biol Chem 237:1681-5.	ET		Isolated mitochondria	Bovines	Heart
Hatefi 1962 J Biol Chem-XLII	1962	Hatefi Y, Haavik AG, Fowler LR, Griffiths DE (1962) Studies on the electron transfer system XLII. Reconstitution of the electron transfer system. J Biol Chem 237:2661-9. https://doi.org/10.1016/S0021-9258(19)73804-6	ET		Isolated mitochondria	Bovines	Heart
Azzone 1961 J Biol Chem	1961	Azzone GF, Ernster L (1961) Demonstration of a requirement of high energy phosphate for the aerobic oxidation of succinate in liver mitochondria. J Biol Chem 236:1518-25.	OXPHOS ET	S	Isolated mitochondria	Rat	Liver
Hatefi 1961 Biochim Biophys Acta	1961	Hatefi Y, Haavik AG, Jurtshuk P (1961) Studies on the electron transport system XXXI. DPNH-cytochrome c reductase II. Biochim Biophys Acta 52:106-18.	ET		Isolated mitochondria	Bovines	Heart

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