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From Bioblast
Year | Reference | Coupling | Pathway | Preparation | Organism | Tissue;cell | |
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Cervoni 2017 J Exp Biol | 2017 | Cervoni MS, Cardoso-Júnior CAM, Craveiro G, Souza AO, Alberici LC, Hartfelder K (2017) Mitochondrial capacity, oxidative damage and hypoxia gene expression are associated with age-related division of labor in honey bee (Apis mellifera L.) workers. J Exp Biol 220:4035-46. | LEAK ROUTINE OXPHOS ET | N ROX | Intact cells | ||
Cunha-de 2017 Thesis | 2017 | Cunha-de Padua MM (2017) Mecanismos citotóxicos da galactomanana de sementes de Schizolobium amazonicum e seus complexos com oxovanádio em células de hepatocarcinoma humano (HepG2) e efeito do silenciamento da enzima glucose-6-fosfato isomerase (GPI) na sobrevivência de células de adenocarcinoma de cólon humano (LS174T). Doctoral Thesis p160. | LEAK ROUTINE OXPHOS ET | N NS ROX | Intact cells Permeabilized cells | Human | Liver Other cell lines |
Chin 2017 US Patent | 2017 | Chin MT, Chien WM, Dinca A (2017) Methods for treating and preventing cardiomyopathy. US Patent WO2016094791A1. | LEAK OXPHOS ET | N CIV ROX | Homogenate | Mouse | Heart |
Asseburg 2017 Thesis | 2017 | Asseburg H (2017) Untersuchungen zur nutritiven Prävention der Neurodegeneration – Wirkungen von Trauben- und Olivenpolyphenolen auf die mitochondriale und kognitive Dysfunktion bei der Gehirnalterung und Alzheimer-Erkrankung. Dissertation p296. | LEAK OXPHOS ET | N S CIV NS ROX | Permeabilized cells Isolated mitochondria Intact cells | Mouse Rat | Nervous system Other cell lines |
Selwood 2017 US Patent | 2017 | Selwood DL, Baker D, Szabadkai G, Duchen MR, Hill JM, Warne JND (2017) Quinolium conjugates of cyclosporin. US Patent US20170349632 A1. | LEAK OXPHOS ET | N ROX | Isolated mitochondria | Mouse | Liver |
Comelli 2017 J Bioenerg Biomembr | 2017 | Comelli M, Pretis I, Buso A, Mavelli I (2017) Mitochondrial energy metabolism and signalling in human glioblastoma cell lines with different PTEN gene status. J Bioenerg Biomembr 50:33-52. | LEAK ROUTINE OXPHOS ET | N Gp CIV NS ROX | Intact cells Permeabilized cells | Human | Nervous system |
Dent 2017 Mol Metab | 2017 | Dent JR, Martins VF, Svensson K, LaBarge SA, Schlenk NC, Esparza MC, Buckner EH, Meyer GA, Hamilton DL, Schenk S, Philp A (2017) Muscle-specific knockout of general control of amino acid synthesis 5 (GCN5) does not enhance basal or endurance exercise-induced mitochondrial adaptation. Mol Metab 6:1574-84. | LEAK OXPHOS ET | F N S NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
Scheede-Bergdahl 2017 Can J Physiol Pharmacol | 2017 | Scheede-Bergdahl C, Bergdahl A (2017) Adaptation of mitochondrial expression and ATP production in dedifferentiating vascular smooth muscle cells. Can J Physiol Pharmacol 95:1473-9. | LEAK OXPHOS | F N CIV NS ROX | Permeabilized tissue | Mouse | Endothelial;epithelial;mesothelial cell |
Tueller 2017 Biochem Biophys Res Commun | 2017 | Tueller DJ, Harley JS, Hancock CR (2017) Effects of curcumin and ursolic acid on the mitochondrial coupling efficiency and hydrogen peroxide emission of intact skeletal myoblasts. Biochem Biophys Res Commun 492:368-72. | LEAK ROUTINE OXPHOS | F N NS ROX | Permeabilized cells Intact cells | Skeletal muscle | |
Dechandt 2017 J Bioenerg Biomembr | 2017 | Dechandt CRP, Zuccolotto-Dos-Reis FH, Teodoro BG, Fernandes AMAP, Eberlin MN, Kettelhut IC, Curti C, Alberici LC (2017) Triacsin C reduces lipid droplet formation and induces mitochondrial biogenesis in primary rat hepatocytes. J Bioenerg Biomembr 49:399-411. | LEAK ROUTINE ET | F N ROX | Permeabilized cells Intact cells | Rat | Liver |
Stepanova 2017 J Cereb Blood Flow Metab | 2017 | Stepanova A, Kahl A, Konrad C, Ten V, Starkov AS, Galkin A (2017) Reverse electron transfer results in a loss of flavin from mitochondrial complex I: Potential mechanism for brain ischemia-reperfusion injury. J Cereb Blood Flow Metab 37:3649-58. | OXPHOS ET LEAK | N NS ROX | Isolated mitochondria | Mouse | Nervous system |
Yu 2017 Free Radic Biol Med | 2017 | Yu Y, Wang L, Delguste F, Durand A, Guilbaud A, Rousselin C, Schmidt AM, Tessier F, Boulanger E, Neviere R (2017) Advanced glycation end products receptor RAGE controls myocardial dysfunction and oxidative stress in high-fat fed mice by sustaining mitochondrial dynamics and autophagy-lysosome pathway. Free Radic Biol Med 112:397-410. | LEAK OXPHOS | F N CIV ROX | Permeabilized tissue | Mouse | Heart |
De Velasco 2017 Br J Nutr | 2017 | de Velasco PC, Chicaybam G, Ramos-Filho DM, Dos Santos RMAR, Mairink C, Sardinha FLC, El-Bacha T, Galina A, Tavares-do-Carmo MDG (2017) Maternal intake of trans-unsaturated or interesterified fatty acids during pregnancy and lactation modifies mitochondrial bioenergetics in the liver of adult offspring in mice. Br J Nutr 118:41-52. | LEAK OXPHOS ET | N NS ROX | Isolated mitochondria | Mouse | Liver |
Yeh 2017 Thesis | 2017 | Yeh A (2017) Modulation of mitochondrial function as an indicator for sublethal effects of contaminants of emerging concern. Dissertation p117. | LEAK OXPHOS ET | N CIV NS ROX | Permeabilized cells Permeabilized tissue | Human Fishes | Liver |
Rowley 2017 Thesis | 2017 | Rowley TJ (2017) The effect of cocoa flavanols on β-cell mass and function. Master's Thesis p131. | OXPHOS ET | N NS ROX | Permeabilized cells | Rat | Islet cell;pancreas;thymus |
Wu 2017 Sci Rep | 2017 | Wu LH, Chang SC, Fu TC, Huang CH, Wang JS (2017) High-intensity interval training improves mitochondrial function and suppresses thrombin generation in platelets undergoing hypoxic stress. Sci Rep 7:4191. | LEAK OXPHOS ET ROUTINE | N NS ROX CIV | Permeabilized cells Intact cells | Human | Blood cells Platelet |
Briston 2017 Sci Rep | 2017 | Briston T, Roberts M, Lewis S, Powney B, M Staddon J, Szabadkai G, Duchen MR (2017) Mitochondrial permeability transition pore: sensitivity to opening and mechanistic dependence on substrate availability. Sci Rep 7:10492. | OXPHOS ET | N S NS ROX | Isolated mitochondria | Rat | Liver |
Lopez 2017 Sci Rep | 2017 | Lopez Sanchez MIG, Waugh HS, Tsatsanis A, Wong BX, Crowston JG, Duce JA, Trounce IA (2017) Amyloid precursor protein drives down-regulation of mitochondrial oxidative phosphorylation independent of amyloid beta. Sci Rep 7:9835. | LEAK OXPHOS ET | N NS ROX | Permeabilized cells | Human | |
Thomsen 2017 Neurobiol Aging | 2017 | Thomsen K, Yokota T, Hasan-Olive MM, Sherazi N, Fakouri NB, Desler C, Regnell CE, Larsen S, Rasmussen LJ, Dela F, Bergersen LH, Lauritzen M (2017) Initial brain aging: heterogeneity of mitochondrial size is associated with decline in complex I-linked respiration in cortex and hippocampus. Neurobiol Aging 61:215-24. | LEAK OXPHOS | N NS ROX | Mouse | Nervous system | |
Parajuli 2017 PLOS ONE | 2017 | Parajuli N, Shrum S, Tobacyk J, Harb A, Arthur JM, MacMillan-Crow LA (2017) Renal cold storage followed by transplantation impairs expression of key mitochondrial fission and fusion proteins. PLOS ONE 12:e0185542. | OXPHOS | N S ROX | Permeabilized tissue | Rat | Kidney |
Nan 2017 Circ Res | 2017 | Nan J, Hu H, Sun Y, Zhu L, Wang Y, Zhong Z, Zhao J, Zhang N, Wang Y, Wang Y, Ye J, Zhang L, Hu X, Zhu W, Wang J (2017) TNFR2 stimulation promotes mitochondrial fusion via Stat3- and NF-kB-dependent activation of OPA1 expression. Circ Res 121:392-410. | OXPHOS ET | N S NS ROX | Intact cells | Mouse | Heart |
Bombaca 2017 Free Radic Biol Med | 2017 | Bombaça ACS, Dias FA, Ennes-Vidal V, Garcia-Gomes ADS, Sorgine MHF, d'Avila-Levy CM, Menna-Barreto RFS (2017) Hydrogen peroxide resistance in Strigomonas culicis: Effects on mitochondrial functionality and Aedes aegypti interaction. Free Radic Biol Med 113:255-66. | ROUTINE | CIV ROX | Intact cells | Protists | |
Permer 2017 Bachelor Thesis | 2017 | Permer M (2017) Respirometrische Charakterisierung kryopräservierter HEK 239T Zellen. Bachelor Thesis 1-56. | LEAK ROUTINE OXPHOS ET | F N S Gp CIV NS ROX | Permeabilized cells Intact cells | Human | Other cell lines HEK |
Krylova 2017 Biomed Khim | 2017 | Krylova TD, Tsygankova PG, Itkis YS, Sheremet NL, Nevinitsyna TA, Mikhaylova SV, Zakharova EY (2017) High resolution respirometry in diagnostic of mitochondrial disorders caused by mitochondrial complex I deficiency. Biomed Khim 63:327-33. | ET | N S NS ROX | Permeabilized cells Intact cells | Human | Endothelial;epithelial;mesothelial cell Fibroblast |
Lang 2017 Aging (Albany NY) | 2017 | Lang A, Anand R, Altinoluk-Hambüchen S, Ezzahoini H, Stefanski A, Iram A, Bergmann L, Urbach J, Böhler P, Hänsel J, Franke M, Stühler K, Krutmann J, Scheller J, Stork B, Reichert AS, Piekorz RP (2017) SIRT4 interacts with OPA1 and regulates mitochondrial quality control and mitophagy. Aging (Albany NY) 9:2163-89. | LEAK ET ROUTINE | ROX | Intact cells | Human | Kidney HEK |
White 2017 Sci Rep | 2017 | White SH, Warren LK, Li C, Wohlgemuth SE (2017) Submaximal exercise training improves mitochondrial efficiency in the gluteus medius but not in the triceps brachii of young equine athletes. Sci Rep 7:14389. | LEAK OXPHOS ET | N NS ROX | Permeabilized tissue | Horse | Skeletal muscle |
Santos 2017 Sci Rep | 2017 | Santos GC, Zeidler JD, Pérez-Valencia JA, Sant'Anna-Silva ACB, Da Poian AT, El-Bacha T, Almeida FCL (2017) Metabolomic analysis reveals vitamin D-induced decrease in polyol pathway and subtle modulation of glycolysis in HEK293T cells. Sci Rep 7:9510. | LEAK ET | ROX | Human | Kidney HEK | |
Kanaan 2017 Redox Biol | 2017 | Kanaan GN, Ichim B, Gharibeh L, Maharsy W, Patten DA, Xuan JY, Reunov A, Marshall P, Veinot J, Menzies K, Nemer M, Harper ME (2017) Glutaredoxin-2 controls cardiac mitochondrial dynamics and energetics in mice, and protects against human cardiac pathologies. Redox Biol 14:509-21. | LEAK OXPHOS | N CIV NS ROX | Permeabilized tissue | Mouse | Heart |
Zholobenko 2017 PLOS ONE | 2017 | Zholobenko AV, Mouithys-Mickalad A, Dostal Z, Serteyn D, Modriansky M (2017) On the causes and consequences of the uncoupler-like effects of quercetin and dehydrosilybin in H9c2 cells. PLOS ONE 12:e0185691. | LEAK OXPHOS ET ROUTINE | F N S NS ROX | Permeabilized cells Intact cells | Rat | Heart |
JanssenDuijghuijsen 2017 Front Physiol | 2017 | JanssenDuijghuijsen LM, Grefte S, de Boer VCJ, Zeper L, van Dartel DAM, van der Stelt I, Bekkenkamp-Grovenstein M, van Norren K, Wichers HJ, Keijer J (2017) Mitochondrial ATP depletion disrupts Caco-2 monolayer integrity and internalizes Claudin 7. Front Physiol 8:794. | LEAK ROUTINE ET | ROX | Intact cells | Human | Endothelial;epithelial;mesothelial cell Other cell lines |
Ruiz 2017 Brain Pathol | 2017 | Ruiz M, Bégou M, Launay N, Ranea-Robles P, Bianchi P, López-Erauskin J, Morató L, Guilera C, Petit B, Vaurs-Barriere C, Guéret-Gonthier C, Bonnet-Dupeyron MN, Fourcade S, Auwerx J, Boespflug-Tanguy O, Pujol A (2017) Oxidative stress and mitochondrial dynamics malfunction are linked in Pelizaeus-Merzbacher disease. Brain Pathol 28:611-30. | LEAK ROUTINE ET | ROX | Intact cells | Human Mouse | Nervous system Fibroblast |
Djordjevic 2017 Neuroscience | 2017 | Djordjevic J, Thomson E, Chowdhury SR, Snow WM, Perez C, Wong TP, Fernyhough P, Albensi BC (2017) Brain region- and sex-specific alterations in mitochondrial function and NF-κB signaling in the TgCRND8 mouse model of Alzheimer's disease. Neuroscience 361:81-92. | ROUTINE OXPHOS ET | N S ROX | Isolated mitochondria | Mouse | Nervous system |
Mueller 2017 Orphanet J Rare Dis | 2017 | Mueller SM, Gehrig SM, Petersen JA, Frese S, Mihaylova V, Ligon-Auer M, Khmara N, Nuoffer JM, Schaller A, Lundby C, Toigo M, Jung HH (2017) Effects of endurance training on skeletal muscle mitochondrial function in Huntington disease patients. Orphanet J Rare Dis 12:184. | LEAK OXPHOS ET | F N S CIV NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Hu 2017 Proc Natl Acad Sci U S A | 2017 | Hu H, Nan J, Sun Y, Zhu D, Xiao C, Wang Y, Zhu L, Wu Y, Zhao J, Wu R, Chen J, Yu H, Hu X, Zhu W, Wang J (2017) Electron leak from NDUFA13 within mitochondrial complex I attenuates ischemia-reperfusion injury via dimerized STAT3. Proc Natl Acad Sci U S A 114:11908-13. | OXPHOS | N S CIV NS ROX | Isolated mitochondria | Mouse | |
MiPNet21.14 Reference sample HRR | 2016-10-19 | Development of a reference sample for HRR. | LEAK ROUTINE OXPHOS ET | F N S Gp CIV NS Other combinations ROX | Intact cells Permeabilized cells | Human | HEK |
MiPNet21.12 Comparison mt respiration media | 2016-10-18 | O2k-MultiSensor: Mitochondrial respiration media for HRR and simultaneous O2k-Fluorometry. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Intact cells Permeabilized cells | Human | HEK |
MiPNet21.13 Comparison mt-preparations | 2016-10-18 | O2k-Protocols: Mitochondrial preparations for HRR. | LEAK OXPHOS ET | N S NS ROX | Permeabilized cells Homogenate Isolated mitochondria | Mouse | Heart |
MiPNet10.04 CellRespiration | 2016-08-08 | An experiment with high-resolution respirometry: coupling control in cell respiration. | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Blood cells |
MiPNet21.07 MitoFit DatLab PT | 2016-07-20 | MitoFit DatLab proficiency test. | LEAK OXPHOS ET | F N S Gp CIV Other combinations ROX | Permeabilized cells | Human | |
Jang 2016 J Intensive Care Med | 2016 | Jang DH, Greenwood JC, Spyres MB, Eckmann D (2016) Measurement of mitochondrial respiration and motility in acute care: sepsis, trauma, and poisoning. J Intensive Care Med 32:86-94. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells Lymphocyte |
Barth 2016 Thesis | 2016 | Barth C (2016) Effekte einer intermittierenden Hyperoxie auf die mitochondriale Atmung in Alveolarmakrophagen. Dissertation p69. | LEAK ROUTINE OXPHOS | N S CIV NS ROX | Permeabilized cells Intact cells | Mouse | Lung;gill Macrophage-derived |
Dias 2016 Neurobiol Aging | 2016 | Dias C, Lourenço CF, Ferreiro E, Barbosa RM, Laranjinha J, Ledo A (2016) Age-dependent changes in the glutamate-nitric oxide pathway in the hippocampus of the triple transgenic model of Alzheimer's disease: implications for neurometabolic regulation. Neurobiol Aging 46:84-95. | LEAK ET | N S ROX | Permeabilized tissue | Mouse | Nervous system |
Jiroutkova 2016 JPEN J Parenter Enteral Nutr | 2016 | Jiroutková K, Krajčová A, Žiak J, Fric M, Gojda J, Džupa V, Kalous M, Tůmová J, Trnka J, Duška F (2016) Mitochondrial function in an in vitro model of skeletal muscle of patients with protracted critical illness and intensive care unit-acquired weakness. JPEN J Parenter Enteral Nutr 41:1213-21. | LEAK ET | F ROX | Human | Skeletal muscle Other cell lines | |
Price 2016 J Thermal Biol | 2016 | Price ER, Sirsat TS, Sirsat SKG, Kang G, Keereetaweep J, Aziz M, Chapman KD, Dzialowski EM (2016) Thermal acclimation in American alligators: Effects of temperature regime on growth rate, mitochondrial function, and membrane composition. J Thermal Biol p11. | LEAK OXPHOS ET | N S CIV NS ROX | Permeabilized tissue | Reptiles | Heart Skeletal muscle |
Lemieux 2016 Mitochondrion | 2016 | Lemieux H, Boemer F, van Galen G, Serteyn D, Amory H, Baise E, Cassart D, van Loon G, Marcillaud-Pitel C, Votion DM (2016) Mitochondrial function is altered in horse atypical myopathy. Mitochondrion 30:35-41. | OXPHOS ET | N S NS ROX | Permeabilized tissue | Horse | Skeletal muscle |
Kimball 2016 Thesis | 2016 | Kimball RL (2016) The role of hypoxia on pyruvate kinase M2, mammalian target of rapamycin, mitochondrial function, and cell invasion in the trophoblast. Master Thesis p55. | LEAK OXPHOS ET | N S NS ROX | Permeabilized cells | Human | Genital Other cell lines |
Gregg 2016 Diabetes | 2016 | Gregg T, Poudel C, Schmidt BA, Dhillon RS, Sdao SM, Truchan NA, Baar EL, Fernandez LA, Denu JM, Eliceiri KW, Rogers JD, Kimple ME, Lamming DW, Merrins MJ (2016) Pancreatic β cells from mice offset age-associated mitochondrial deficiency with reduced KATP channel activity. Diabetes 65:2700-10. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Human Mouse | Islet cell;pancreas;thymus Other cell lines |
Camacho-Pereira 2016 Cell Metab | 2016 | Camacho-Pereira J, Tarragó MG, Chini CC, Nin V, Escande C, Warner GM, Puranik AS, Schoon RA, Reid JM, Galina A, Chini EN (2016) CD38 dictates age-related NAD decline and mitochondrial dysfunction through an SIRT3-dependent mechanism. Cell Metab 23:1127-39. | LEAK ROUTINE OXPHOS ET | S ROX | Isolated mitochondria Intact cells | Human Mouse | Liver Lung;gill Other cell lines |
Ryan 2016 Diabetes | 2016 | Ryan TE, Schmidt CA, Green TD, Spangenburg EE, Neufer PD, McClung JM (2016) Targeted expression of catalase to mitochondria protects against ischemic myopathy in high fat fed mice. Diabetes 65:2553-68. | LEAK OXPHOS ET | N S CIV Other combinations ROX | Isolated mitochondria | Mouse | Skeletal muscle |
Franko 2016 Diabetes | 2016 | Franko A, Huypens P, Neschen S, Irmler M, Rozman J, Rathkolb B, Neff F, Prehn C, Dubois G, Baumann M, Massinger R, Gradinger D, Przemeck GK, Repp B, Aichler M, Feuchtinger A, Schommers P, Stöhr O, Sanchez-Lasheras C, Adamski J, Peter A, Prokisch H, Beckers J, Walch AK, Fuchs H, Wolf E, Schubert M, Wiesner RJ, Hrabě de Angelis M (2016) Bezafibrate improves insulin sensitivity and metabolic flexibility in STZ-treated diabetic mice. Diabetes 65:2540-52. | LEAK OXPHOS | N S CIV ROX | Permeabilized cells Permeabilized tissue | Human | Skeletal muscle Fibroblast |
Christensen 2016 J Appl Physiol (1985) | 2016 | Christensen PM, Jacobs RA, Bonne T, Flück D, Bangsbo J, Lundby C (2016) A short period of high-intensity interval training improves skeletal muscle mitochondrial function and pulmonary oxygen uptake kinetics. J Appl Physiol (1985) 120:1319-27. | LEAK OXPHOS ET | F N S CIV NS Other combinations ROX | Permeabilized tissue | Human | Skeletal muscle |
Ryan 2016 J Mol Cell Cardiol | 2016 | Ryan TE, Schmidt CA, Alleman RJ, Tsang AM, Green TD, Neufer PD, Brown DA, McClung JM (2016) Mitochondrial therapy improves limb perfusion and myopathy following hindlimb ischemia. J Mol Cell Cardiol 97:191-6. | LEAK OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Mouse | Skeletal muscle |
Wijermars 2016 Am J Transplant | 2016 | Wijermars LG, Schaapherder AF, Kostidis S, Wüst RC, Lindeman JH (2016) Succinate accumulation and ischemia reperfusion injury: of mice but not men - A study in renal ischemia reperfusion. Am J Transplant 16:2741-6. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Human Pig Mouse Rat | Kidney |
Peyta 2016 Biochim Biophys Acta | 2016 | Peyta L, Jarnouen K, Pinault M, Guimaraes C, Pais de Barros JP, Chevalier S, Dumas JF, Maillot F, Hatch GM, Loyer P, Servais S (2016) Reduced cardiolipin content decreases respiratory chain capacities and increases ATP synthesis yield in the human HepaRG cells. Biochim Biophys Acta 1857:443-53. | LEAK OXPHOS ET | N CIV NS ROX | Permeabilized cells | Human | Liver Other cell lines |
Kontro 2016 Thesis | 2016 | Kontro H (2016) Mitochondrial function and sirtuin expression in hippocampus of young and old high and low-capacity runner rats. Master's Thesis p35. | LEAK OXPHOS ET | N S NS ROX | Homogenate | Rat | Nervous system |
Reis 2016 Aging (Albany NY) | 2016 | Reis FC, Branquinho JL, Brandão BB, Guerra BA, Silva ID, Frontini A, Thomou T, Sartini L, Cinti S, Kahn CR, Festuccia WT, Kowaltowski AJ, Mori MA (2016) Fat-specific Dicer deficiency accelerates aging and mitigates several effects of dietary restriction in mice. Aging (Albany NY) 8:1201-22. | LEAK | N S ROX | Permeabilized cells | Mouse | Fat |
Sheremet 2016 Biochemistry (Moscow) | 2016 | Sheremet NL, Nevinitsyna TA, Zhorzholadze NV, Ronzina IA, Itkis YS, Krylova TD, Tsygankova PG, Malakhova VA, Zakharova EY, Tokarchuk AV, Panteleeva AA, Karger EM, Lyamzaev KG, Avetisov SE (2016) Previously unclassified mutation of mtDNA m.3472T>C: evidence of pathogenicity in Leber’s hereditary optic neuropathy. Biochemistry (Moscow) BM16-078. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | Endothelial;epithelial;mesothelial cell Fibroblast Platelet |
Scrima 2016 Biochim Biophys Acta | 2016 | Scrima R, Cela O, Merla G, Augello B, Rubino R, Quarato G, Fugetto S, Menga M, Fuhr L, Relógio A, Piccoli C, Mazzoccoli G, Capitanio N (2016) Clock-genes and mitochondrial respiratory activity: Evidence of a reciprocal interplay. Biochim Biophys Acta 1857:1344-51. | LEAK ROUTINE ET | ROX | Intact cells | Human | Liver Endothelial;epithelial;mesothelial cell Other cell lines Fibroblast |
Du 2016 Aquat Toxicol | 2016 | Du X, Crawford DL, Nacci DE, Oleksiak MF (2016) Heritable oxidative phosphorylation differences in a pollutant resistant Fundulus heteroclitus population. Aquat Toxicol 177:44-50. | LEAK OXPHOS ET | N S CIV Other combinations ROX | Permeabilized cells | Fishes | Liver |
Holandino 2016 Bioelectrochemistry | 2016 | Holandino C, Teixeira CA, de Oliveira FA, Barbosa GM, Siqueira CM, Messeder DJ, de Aguiar FS, da Veiga VF, Girard-Dias W, Miranda K, Galina A, Capella MA, Morales MM (2016) Direct electric current treatment modifies mitochondrial function and lipid body content in the A549 cancer cell line. Bioelectrochemistry 111:83-92. | LEAK ROUTINE ET | ROX | Intact cells | Human | Lung;gill Other cell lines |
Hamilton 2016 Am J Physiol Heart Circ Physiol | 2016 | Hamilton DJ, Zhang A, Li S, Cao TN, Smith JA, Vedula I, Cordero-Reyes AM, Youker KA, Torre-Amione G, Gupte AA (2016) Combination of angiotensin II and l-NG-nitroarginine methyl ester exacerbates mitochondrial dysfunction and oxidative stress to cause heart failure. Am J Physiol Heart Circ Physiol 310:H667-80. | LEAK OXPHOS | F N S NS Other combinations ROX | Permeabilized tissue Isolated mitochondria | Mouse | Heart |
Sengupta 2016 Free Radic Biol Med | 2016 | Sengupta S, Yang G, O'Donnell JC, Hinson MD, McCormack SE, Falk MJ, La P, Robinson MB, Williams ML, Yohannes MT, Polyak E, Nakamaru-Ogiso E, Dennery PA (2016) The circadian gene Rev-erbα improves cellular bioenergetics and provides preconditioning for protection against oxidative stress. Free Radic Biol Med 93:177-89. | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Lung;gill Fibroblast |
Berschneider 2016 Thesis | 2016 | Berschneider K (2016) Connecting the functions of the proteasome and mitochondria in the lung. Dissertation p161. | LEAK ROUTINE ET | ROX | Permeabilized cells | Mouse | Lung;gill |
Watala 2016 Int J Pharm | 2016 | Watala C, Karolczak K, Kassassir H, Siewiera K, Maczynska K, Pieniazek A, Labieniec-Watala M (2016) How do the full-generation poly(amido)amine (PAMAM) dendrimers activate blood platelets? Platelet membrane zeta potential and other membrane-associated phenomena. Int J Pharm 500:379-89. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells Platelet |
Brandt 2016 Chem Biol Interact | 2016 | Brandt AP, Gozzi GJ, Pires Ado R, Martinez GR, Dos Santos Canuto AV, Echevarria A, Di Pietro A, Cadena SM (2016) Impairment of oxidative phosphorylation increases the toxicity of SYD-1 on hepatocarcinoma cells (HepG2). Chem Biol Interact 256:154-60. | LEAK ROUTINE ET | ROX | Intact cells | Human | Liver Other cell lines |
Liu 2016 EMBO Mol Med | 2016 | Liu J, Liang X, Zhou D, Lai L, Xiao L, Liu L, Fu T, Kong Y, Zhou Q, Vega RB, Zhu MS, Kelly DP, Gao X, Gan Z (2016) Coupling of mitochondrial function and skeletal muscle fiber type by a miR-499/Fnip1/AMPK circuit. EMBO Mol Med 8:1212-1228. | LEAK OXPHOS ET | N ROX | Permeabilized cells Permeabilized tissue | Mouse | Skeletal muscle |
Granata 2016 FASEB J | 2016 | Granata C, Oliveira RS, Little JP, Renner K, Bishop DJ (2016) Mitochondrial adaptations to high-volume exercise training are rapidly reversed after a reduction in training volume in human skeletal muscle. FASEB J 30:3413-23. https://doi.org/10.1096/fj.201500100R | LEAK OXPHOS ET | N S CIV NS ROX | Permeabilized tissue | Human | Skeletal muscle |
McCourt 2016 PLOS ONE | 2016 | McCourt AC, Jakobsson L, Larsson S, Holm C, Piel S, Elmér E, Björkqvist M (2016) White adipose tissue browning in the R6/2 mouse model of Huntington's disease. PLOS ONE 11:e0159870. | LEAK OXPHOS ET | NS ROX | Permeabilized cells | Mouse | Fat |
Kilbaugh 2016 Mitochondrion | 2016 | Kilbaugh TJ, Karlsson M, Duhaime AC, Hansson MJ, Elmer E, Margulies SS (2016) Mitochondrial response in a toddler-aged swine model following diffuse non-impact traumatic brain injury. Mitochondrion 26:19-25. | LEAK OXPHOS ET | N S CIV NS ROX | Homogenate | Pig | Nervous system |
Tsai 2016 Sci Rep | 2016 | Tsai HH, Chang SC, Chou CH, Weng TP, Hsu CC, Wang JS (2016) Exercise training alleviates hypoxia-induced mitochondrial dysfunction in the lymphocytes of sedentary males. Sci Rep 6:35170. | LEAK ROUTINE OXPHOS ET | F N S NS Other combinations ROX | Permeabilized cells Intact cells | Human | Lymphocyte Blood cells |
Peruzzo 2016 Cell Cycle | 2016 | Peruzzo P, Comelli M, Di Giorgio E, Franforte E, Mavelli I, Brancolini C (2016) Transformation by different oncogenes relies on specific metabolic adaptations. Cell Cycle 15:2656-68. | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Fibroblast |
Anand 2016 PLOS ONE | 2016 | Anand R, Strecker V, Urbach J, Wittig I, Reichert AS (2016) Mic13 is essential for formation of crista junctions in mammalian cells. PLOS ONE 11:e0160258. | LEAK ROUTINE OXPHOS ET | N CIV NS Other combinations ROX | Permeabilized cells Intact cells | HEK | |
Takahashi 2016 Exp Gerontol | 2016 | Takahashi K, Ohsawa I, Shirasawa T, Takahashi M (2016) Early-onset motor impairment and increased accumulation of phosphorylated α-synuclein in the motor cortex of normal aging mice are ameliorated by coenzyme Q. Exp Gerontol 81:65-75. | OXPHOS | N S ROX | Isolated mitochondria | Mouse | Nervous system |
Boeck 2016 Mitochondrion | 2016 | Boeck C, Koenig AM, Schury K, Geiger ML, Karabatsiakis A, Wilker S, Waller C, Gündel H, Fegert JM, Calzia E, Kolassa IT (2016) Inflammation in adult women with a history of child maltreatment: The involvement of mitochondrial alterations and oxidative stress. Mitochondrion 30:197-207. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells Lymphocyte |
Li 2016 Sci Rep | 2016 | Li N, Guenancia C, Rigal E, Hachet O, Chollet P, Desmoulins L, Leloup C, Rochette L, Vergely C (2016) Short-term moderate diet restriction in adulthood can reverse oxidative, cardiovascular and metabolic alterations induced by postnatal overfeeding in mice. Sci Rep 6:30817 | LEAK OXPHOS | N NS ROX | Permeabilized tissue | Mouse | Heart |
Gehrig 2016 Orphanet J Rare Dis | 2016 | Gehrig SM, Mihaylova V, Frese S, Mueller SM, Ligon-Auer M, Spengler CM, Petersen JA, Lundby C, Jung HH (2016) Altered skeletal muscle (mitochondrial) properties in patients with mitochondrial DNA single deletion myopath. Orphanet J Rare Dis 11:105. | LEAK OXPHOS | F N S CIV NS Other combinations ROX | Permeabilized tissue | Human | Skeletal muscle |
Moon 2016 J Biol Chem | 2016 | Moon SH, Mancuso DJ, Sims HF, Liu X, Nguyen AL, Yang K, Guan S, Dilthey BG, Jenkins CM, Weinheimer CJ, Kovacs A, Abendschein D, Gross RW (2016) Cardiac myocyte-specific knock-out of calcium-independent phospholipase A2γ (iPLA2γ) decreases oxidized fatty acids during ischemia/reperfusion and reduces infarct size. J Biol Chem 291:19687-700. | LEAK OXPHOS | F N S NS Other combinations ROX | Isolated mitochondria | Mouse | Heart |
Vevera 2016 Physiol Res | 2016 | Vevera J, Fišar Z, Nekovářová T, Vrablík M, Zlatohlávek L, Hroudová J, Singh N, Raboch J, Valeš K (2016) Statin-induced changes in mitochondrial respiration in blood platelets in rats and human with dyslipidemia. Physiol Res 65:777-88. | LEAK ROUTINE OXPHOS ET | N S NS Other combinations ROX | Intact cells Permeabilized cells | Human Rat | Blood cells Platelet |
Teulier 2016 Proc Biol Sci | 2016 | Teulier L, Weber JM, Crevier J, Darveau CA (2016) Proline as a fuel for insect flight: enhancing carbohydrate oxidation in hymenopterans. Proc Biol Sci 283: 20160333. | OXPHOS | F N S Gp NS Other combinations ROX | Permeabilized tissue | Hexapods | Skeletal muscle |
Hagl 2016 Neuromolecular Med | 2016 | Hagl S, Asseburg H, Heinrich M, Sus N, Blumrich EM, Dringen R, Frank J, Eckert GP (2016) Effects of long-term rice bran extract supplementation on survival, cognition and brain mitochondrial function in aged NMRI mice. Neuromolecular Med 18:347-63. | LEAK OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Mouse | Nervous system |
Oliveira 2016 PLOS ONE | 2016 | Oliveira MP, Correa Soares JB, Oliveira MF (2016) Sexual preferences in nutrient utilization regulate oxygen consumption and reactive oxygen species generation in Schistosoma mansoni: potential implications for parasite redox biology. PLOS ONE 11:e0158429. | LEAK ROUTINE | F ROX | Intact organism | Other invertebrates | |
Schoenenberger 2016 Cancer Res | 2016 | Schönenberger D, Harlander S, Rajski M, Jacobs RA, Lundby AK, Adlesic M, Hejhal T, Wild PJ, Lundby C, Frew IJ (2016) Formation of renal cysts and tumors in Vhl/Trp53-deficient mice requires HIF1α and HIF2α. Cancer Res 76:2025-36. | OXPHOS ET | F N S CIV NS ROX | Permeabilized tissue | Mouse | Nervous system |
Wang 2016 Toxicol Sci | 2016 | Wang L, Espinoza HM, MacDonald JW, Bammler TK, Williams CR, Yeh A, Louie KW, Marcinek DJ, Gallagher EP (2016) Olfactory Transcriptional Analysis of Salmon Exposed to Mixtures of Chlorpyrifos and Malathion Reveal Novel Molecular Pathways of Neurobehavioral Injury. Toxicol Sci 149:145-57. | LEAK OXPHOS ET | N S CIV NS ROX | Permeabilized tissue | Fishes | Endothelial;epithelial;mesothelial cell |
Jang 2016 Clin Toxicol (Phila) | 2016 | Jang DH, Shofer FS, Weiss SL, Becker LB (2016) Impairment of mitochondrial respiration following ex vivo cyanide exposure in peripheral blood mononuclear cells. Clin Toxicol (Phila) 54:303-7. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells Lymphocyte |
Johnson 2016 Diabetes | 2016 | Johnson ML, Distelmaier K, Lanza IR, Irving BA, Robinson MM, Konopka AR, Shulman GI, Nair KS (2016) Mechanism by which caloric restriction improves insulin sensitivity in sedentary obese adults. Diabetes 65:74-84. | LEAK OXPHOS ET | N S NS ROX | Isolated mitochondria | Human | Skeletal muscle |
Li 2016 J Appl Physiol (1985) | 2016 | Li C, White SH, Warren LK, Wohlgemuth SE (2016) Effects of aging on mitochondrial function in skeletal muscle of quarter horses. J Appl Physiol (1985) 121:299-311. | LEAK OXPHOS ET | N NS ROX | Permeabilized tissue | Horse | Skeletal muscle |
Chu 2016 World J Gastroenterol | 2016 | Chu MJ, Premkumar R, Hickey AJ, Jiang Y, Delahunt B, Phillips AR, Bartlett A (2016) Steatotic livers are susceptible to normothermic ischemia-reperfusion injury from mitochondrial Complex-I dysfunction. World J Gastroenterol 22:4673-84. | LEAK OXPHOS ET | N S NS ROX | Homogenate | Rat | Liver |
Schoepf 2016 FEBS J | 2016 | Schöpf B, Schäfer G, Weber A, Talasz H, Eder IE, Klocker H, Gnaiger E (2016) Oxidative phosphorylation and mitochondrial function differ between human prostate tissue and cultured cells. https://doi.org/10.1111/febs.13733 | LEAK OXPHOS ET | F N S NS Other combinations ROX | Permeabilized cells Permeabilized tissue | Human | Endothelial;epithelial;mesothelial cell Genital Other cell lines Fibroblast |
Puskarich 2016 J Crit Care | 2016 | Puskarich MA, Kline JA, Watts JA, Shirey K, Hosler J, Jones AE (2016) Early alterations in platelet mitochondrial function are associated with survival and organ failure in patients with septic shock. J Crit Care 31:63-7. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells Platelet |
Strifler 2016 PLOS ONE | 2016 | Strifler G, Tuboly E, Szél E, Kaszonyi E, Cao C, Kaszaki J, Mészáros A, Boros M, Hartmann P (2016) Inhaled methane limits the mitochondrial electron transport chain dysfunction during experimental liver ischemia-reperfusion injury. PLOS ONE 11:e0146363. | LEAK OXPHOS | N S CIV NS ROX | Homogenate Isolated mitochondria | Rat | Liver |
Farsijani 2016 J Clin Invest | 2016 | Farsijani NM, Liu Q, Kobayashi H, Davidoff O, Sha F, Fandrey J, Ikizler TA, O'Connor PM, Haase VH (2016) Renal epithelium regulates erythropoiesis via HIF-dependent suppression of erythropoietin. J Clin Invest 126:1425-37. | LEAK OXPHOS | N S CIV ROX | Permeabilized tissue | Mouse | Nervous system |
Wolff 2016 J Evol Biol | 2016 | Wolff JN, Pichaud N, Camus MF, Côté G, Blier PU, Dowling DK (2016) Evolutionary implications of mitochondrial genetic variation: mitochondrial genetic effects on OXPHOS respiration and mitochondrial quantity change with age and sex in fruit flies. J Evol Biol 29:736-47. | LEAK OXPHOS ET | N Gp CIV Other combinations ROX | Permeabilized tissue | Drosophila | Skeletal muscle |
Siewiera 2016 Life Sci | 2016 | Siewiera K, Kassassir H, Talar M, Wieteska L, Watala C (2016) Higher mitochondrial potential and elevated mitochondrial respiration are associated with excessive activation of blood platelets in diabetic rats. Life Sci 148:293-304. | LEAK ROUTINE ET | ROX | Intact cells | Rat | Blood cells Platelet |
Salin 2016 J Exp Biol | 2016 | Salin K, Auer SK, Anderson GJ, Selman C, Metcalfe NB (2016) Inadequate food intake at high temperatures is related to depressed mitochondrial respiratory capacity. J Exp Biol 219:1356-62. | LEAK OXPHOS | N S CIV NS Other combinations ROX | Permeabilized tissue | Fishes | Skeletal muscle Liver |
Pamenter 2016 Biol Lett | 2016 | Pamenter ME, Gomez CR, Richards JG, Milsom WK (2016) Mitochondrial responses to prolonged anoxia in brain of red-eared slider turtles. Biol Lett 12. pii: 20150797. | LEAK OXPHOS ET | N S CIV ROX | Permeabilized tissue | Reptiles | Nervous system |
Lim 2016 FASEB J | 2016 | Lim SC, Hroudová J, Van Bergen NJ, Lopez Sanchez MI, Trounce IA, McKenzie M (2016) Loss of mitochondrial DNA-encoded protein ND1 results in disruption of complex I biogenesis during early stages of assembly. FASEB J 30:2236-48. | OXPHOS ET | N S NS ROX | Permeabilized cells | Human | Other cell lines |
Xiong 2016 Hypertension | 2016 | Xiong S, Wang P, Ma L, Gao P, Gong L, Li L, Li Q, Sun F, Zhou X, He H, Chen J, Yan Z, Liu D, Zhu Z (2016) Ameliorating endothelial mitochondrial dysfunction restores coronary function via transient receptor potential vanilloid 1-mediated protein kinase A/uncoupling protein 2 pathway. Hypertension 67:451-60. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Intact cells Permeabilized cells | Human | Endothelial;epithelial;mesothelial cell Other cell lines |
Castellano-Gonzalez 2016 Oncotarget | 2016 | Castellano-González G, Pichaud N, Ballard JW, Bessede A, Marcal H, Guillemin GJ (2016) Epigallocatechin-3-gallate induces oxidative phosphorylation by activating cytochrome c oxidase in human cultured neurons and astrocytes. Oncotarget 7:7426-40 | LEAK ROUTINE ET | ROX | Intact cells | Human | Nervous system |
Cheng 2016 Nat Immunol | 2016 | Cheng SC, Scicluna BP, Arts RJ, Gresnigt MS, Lachmandas E, Giamarellos-Bourboulis EJ, Kox M, Manjeri GR, Wagenaars JA, Cremer OL, Leentjens J, van der Meer AJ, van de Veerdonk FL, Bonten MJ, Schultz MJ, Willems PH, Pickkers P, Joosten LA, van der Poll T, Netea MG (2016) Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis. Nat Immunol 17:406-13. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells Lymphocyte |
Cagnone 2016 Sci Rep | 2016 | Cagnone GL, Tsai TS, Makanji Y, Matthews P, Gould J, Bonkowski MS, Elgass KD, Wong AS, Wu LE, McKenzie M, Sinclair DA, John JC (2016) Restoration of normal embryogenesis by mitochondrial supplementation in pig oocytes exhibiting mitochondrial DNA deficiency. Sci Rep 6:23229. | LEAK OXPHOS ET | S ROX | Isolated mitochondria | Pig | Genital |
Ejaz 2016 Diabetes | 2016 | Ejaz A, Martinez-Guino L, Goldfine AB, Ribas-Aulinas F, De Nigris V, Ribó S, Gonzalez-Franquesa A, Garcia-Roves PM, Li E, Dreyfuss JM, Gall W, Kim JK, Bottiglieri T, Villarroya F, Gerszten RE, Patti ME, Lerin C (2016) Dietary betaine supplementation increases Fgf21 levels to improve glucose homeostasis and reduce hepatic lipid accumulation in mice. Diabetes 65:902-12. | LEAK OXPHOS | NS Other combinations ROX | Homogenate | Mouse | Fat |
Lund 2016 J Physiol | 2016 | Lund MT, Kristensen M, Hansen M, Tveskov L, Floyd AK, Støckel M, Vainer B, Poulsen SS, Helge JW, Prats C, Dela F (2016) Hepatic mitochondrial oxidative phosphorylation is normal in obese patients with and without type 2 diabetes. J Physiol 594:4351-8. | LEAK OXPHOS ET | F N S CIV NS ROX | Permeabilized tissue | Human | Liver |
Shama 2016 Evol Appl | 2016 | Shama LNS, Mark FC, Strobel A, Lokmer A, John U, Wegner KM (2016) Transgenerational effects persist down the maternal line in marine sticklebacks: gene expression matches physiology in a warming ocean. Evol Appl 10013/epic.47323. | LEAK OXPHOS ET | NS ROX | Permeabilized tissue | Fishes | Heart |
Baeder 2016 Int J Dent | 2016 | Baeder AC, Napa K, Richardson ST, Taylor OJ, Andersen SG, Wilcox SH, Winden DR, Reynolds PR, Bikman BT (2016) Oral gingival cell cigarette smoke exposure induces muscle cell metabolic disruption. Int J Dent 2016:2763160. | LEAK OXPHOS ET | N NS ROX | Permeabilized cells | Mouse | Skeletal muscle |
Jacobs 2016 J Physiol | 2016 | Jacobs RA, Lundby AM, Fenk S, Gehrig S, Siebenmann C, Flück D, Kirk N, Hilty MP, Lundby C (2016) Twenty-eight days of exposure to 3,454 m increases mitochondrial volume density in human skeletal muscle. J Physiol 594:1151-66. | LEAK OXPHOS ET | F N S CIV NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Wijermars 2016 Kidney Int | 2016 | Wijermars LG, Schaapherder AF, de Vries DK, Verschuren L, Wuest RC, Kostidis S, Mayboroda OA, Prins F, Ringers J, Bierau J, Bakker JA, Kooistra T, Lindeman JH (2016) Defective postreperfusion metabolic recovery directly associates with incident delayed graft function. Kidney Int 90:181-91. | OXPHOS | N S NS ROX | Permeabilized tissue | Human | Kidney |
Assmann 2016 Cell Rep | 2016 | Assmann N, Dettmer K, Simbuerger JM, Broeker C, Nuernberger N, Renner K, Courtneidge H, Klootwijk ED, Duerkop A, Hall A, Kleta R, Oefner PJ, Reichold M, Reinders J (2016) Renal fanconi syndrome is caused by a mistargeting-based mitochondriopathy. Cell Rep 15:1423-9. | LEAK OXPHOS ET | F N S NS Other combinations ROX | Intact cells | Pig | Kidney Other cell lines |
Yavari 2016 Cell Metab | 2016 | Yavari A, Stocker CJ, Ghaffari S, Wargent ET, Steeples V, Czibik G, Pinter K, Bellahcene M, Woods A, Martinez de Morentin PB, Cansell C, Lam BY, Chuster A, Petkevicius K, Nguyen-Tu MS, Martinez-Sanchez A, Pullen TJ, Oliver PL, Stockenhuber A, Nguyen C, Lazdam M, O'Dowd JF, Harikumar P, Toth M, Beall C, Kyriakou T, Parnis J, Sarma D, Katritsis G, Wortmann DD, Harper AR, Brown LA, Willows R, Gandra S, Poncio V, de Oliveira Figueiredo MJ, Qi NR, Peirson SN, McCrimmon RJ, Gereben B, Tretter L, Fekete C, Redwood C, Yeo GS, Heisler LK, Rutter GA, Smith MA, Withers DJ, Carling D, Sternick EB, Arch JR, Cawthorne MA, Watkins H, Ashrafian H (2016) Chronic activation of γ2 AMPK induces obesity and reduces β cell function. Cell Metab 23:821-36. | LEAK OXPHOS ET | N NS ROX | Homogenate | Mouse | Nervous system |
Gdynia 2016 Nat Commun | 2016 | Gdynia G, Sauer SW, Kopitz J, Fuchs D, Duglova K, Ruppert T, Miller M, Pahl J, Cerwenka A, Enders M, Mairbäurl H, Kamiński MM, Penzel R, Zhang C, Fuller JC, Wade RC, Benner A, Chang-Claude J, Brenner H, Hoffmeister M, Zentgraf H, Schirmacher P, Roth W (2016) The HMGB1 protein induces a metabolic type of tumour cell death by blocking aerobic respiration. Nat Commun 7:10764. | ROUTINE | ROX | Permeabilized cells | Human | Endothelial;epithelial;mesothelial cell Other cell lines |
Reynolds 2016 Am J Physiol Endocrinol Metab | 2016 | Reynolds MS, Hancock CR, Ray JD, Kener KB, Draney C, Garland K, Hardman J, Bikman BT, Tessem JS (2016) β-cell deletion of Nr4a1 and Nr4a3 nuclear receptors impedes mitochondrial respiration and insulin secretion. Am J Physiol Endocrinol Metab 311:E186-201. | LEAK ROUTINE OXPHOS ET | N S ROX | Permeabilized cells Intact cells | Rat | Islet cell;pancreas;thymus |
Sanchez-Calvo 2016 PLOS ONE | 2016 | Sánchez-Calvo B, Cassina A, Rios N, Peluffo G, Boggia J, Radi R, Rubbo H, Trostchansky A (2016) Nitro-arachidonic acid prevents Angiotensin II-induced mitochondrial dysfunction in a cell line of kidney proximal tubular cells. PLOS ONE 11:e0150459. | LEAK ROUTINE ET | ROX | Intact cells | Human | Kidney Other cell lines |
Lesage 2016 Am J Hum Genet | 2016 | Lesage S, Drouet V, Majounie E, Deramecourt V, Jacoupy M, Nicolas A, Cormier-Dequaire F, Hassoun SM, Pujol C, Ciura S, Erpapazoglou Z, Usenko T, Maurage CA, Sahbatou M, Liebau S, Ding J, Bilgic B, Emre M, Erginel-Unaltuna N, Guven G, Tison F, Tranchant C, Vidailhet M, Corvol JC, Krack P, Leutenegger AL, Nalls MA, Hernandez DG, Heutink P, Gibbs JR, Hardy J, Wood NW, Gasser T, Durr A, Deleuze JF, Tazir M, Destée A, Lohmann E, Kabashi E, Singleton A, Corti O, Brice A (2016) Loss of VPS13C function in autosomal-recessive parkinsonism causes mitochondrial dysfunction and increases PINK1/Parkin-Dependent Mitophagy. Am J Hum Genet 98:500-13. | LEAK ROUTINE ET | ROX | Intact cells | Other mammals | Kidney Other cell lines |
Zabielski 2016 Diabetes | 2016 | Zabielski P, Lanza IR, Gopala S, Holtz Heppelmann CJ, Bergen HR 3rd, Dasari S, Nair KS (2016) Altered skeletal muscle mitochondrial proteome as the basis of disruption of mitochondrial function in diabetic mice. Diabetes 65:561-73. | LEAK OXPHOS ET | F N S NS ROX | Permeabilized cells | Mouse | Skeletal muscle |
Bynum 2016 Transfusion | 2016 | Bynum JA, Adam Meledeo M, Getz TM, Rodriguez AC, Aden JK, Cap AP, Pidcoke HF (2016) Bioenergetic profiling of platelet mitochondria during storage: 4°C storage extends platelet mitochondrial function and viability. Transfusion 56 Suppl 1:S76-84. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells Platelet |
Hagl 2016 Nutr Neurosci | 2016 | Hagl S, Berressem D, Grewal R, Grebenstein N, Frank J, Eckert GP (2016) Rice bran extract improves mitochondrial dysfunction in brains of aged NMRI mice. Nutr Neurosci 19:1-10. | LEAK OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Mouse | Nervous system |
Leucci 2016 Nature | 2016 | Leucci E, Vendramin R, Spinazzi M, Laurette P, Fiers M, Wouters J, Radaelli E, Eyckerman S, Leonelli C, Vanderheyden K, Rogiers A, Hermans E, Baatsen P, Aerts S, Amant F, Van Aelst S, van den Oord J, de Strooper B, Davidson I, Lafontaine DL, Gevaert K, Vandesompele J, Mestdagh P, Marine JC (2016) Melanoma addiction to the long non-coding RNA SAMMSON. Nature 531:518-22. | LEAK OXPHOS ET | N CIV NS ROX | Permeabilized cells | Human | Endothelial;epithelial;mesothelial cell Other cell lines |
Tam 2016 Eur J Appl Physiol | 2016 | Tam E, Bruseghini P, Calabria E, Sacco LD, Doria C, Grassi B, Pietrangelo T, Pogliaghi S, Reggiani C, Salvadego D, Schena F, Toniolo L, Verratti V, Vernillo G, Capelli C (2016) Gokyo Khumbu/Ama Dablam Trek 2012: effects of physical training and high-altitude exposure on oxidative metabolism, muscle composition, and metabolic cost of walking in women. Eur J Appl Physiol 116:129-44. | LEAK OXPHOS | N S NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Grimm 2016 Methods Mol Biol | 2016 | Grimm A, Schmitt K, Eckert A (2016) Advanced mitochondrial respiration assay for evaluation of mitochondrial dysfunction in Alzheimer's disease. Methods Mol Biol 1303:171-83. | LEAK OXPHOS ET | N CIV ROX | Isolated mitochondria | Mouse | Nervous system |
Doerrier 2016 Mitochondrion | 2016 | Doerrier C, García JA, Volt H, Díaz-Casado ME, Luna-Sánchez M, Fernández-Gil B, Escames G, López LC, Acuña-Castroviejo D (2016) Permeabilized myocardial fibers as model to detect mitochondrial dysfunction during sepsis and melatonin effects without disruption of mitochondrial network. Mitochondrion 27:56-63. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Mouse | Heart |
Cacabelos 2016 Acta Neuropathol Commun | 2016 | Cacabelos D, Ramírez-Núñez O, Granado-Serrano AB, Torres P, Ayala V, Moiseeva V, Povedano M, Ferrer I, Pamplona R, Portero-Otin M, Boada J (2016) Early and gender-specific differences in spinal cord mitochondrial function and oxidative stress markers in a mouse model of ALS. Acta Neuropathol Commun 4:3. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized tissue Intact cells | Mouse | Nervous system Other cell lines |
Tunholi 2016 J Invertebr Pathol | 2016 | Tunholi VM, Tunholi-Alves VM, Santos AT, Garcia Jda S, Maldonado A Jr, da-Silva WS, Rodrigues Mde L, Pinheiro J (2016) Evaluation of the mitochondrial system in the gonad-digestive gland complex of Biomphalaria glabrata (Mollusca, Gastropoda) after infection by Echinostoma paraensei (Trematoda, Echinostomatidae). J Invertebr Pathol 136:136-41. | LEAK OXPHOS ET | N NS ROX | Permeabilized tissue | Molluscs | Genital |
Ehinger 2016 Mov Disord | 2016 | Ehinger JK, Morota S, Hansson MJ, Gesine P, Elmér E (2016) Mitochondrial respiratory function in peripheral blood cells from Huntington’s disease patients. Mov Disord doi:10.1002/mdc3.12308. | LEAK ROUTINE OXPHOS ET | N S CIV NS Other combinations ROX | Permeabilized cells Intact cells | Human | Blood cells Lymphocyte Platelet |
LaBarge 2016 FASEB J | 2016 | LaBarge SA, Migdal CW, Buckner EH, Okuno H, Gertsman I, Stocks B, Barshop BA, Nalbandian SR, Philp A, McCurdy CE, Schenk S (2016) p300 is not required for skeletal muscle metabolic adaptation to endurance exercise training. FASEB J 30:1623-33. | LEAK OXPHOS ET | F N NS ROX S Other combinations | Permeabilized tissue | Mouse | Skeletal muscle |
Scialo 2016 Cell Metab | 2016 | Scialò F, Sriram A, Fernández-Ayala D, Gubina N, Lõhmus M, Nelson G, Logan A, Cooper HM, Navas P, Enríquez JA, Murphy MP, Sanz A (2016) Mitochondrial ROS produced via reverse electron transport extend animal lifespan. Cell Metab 23:725-34. | LEAK OXPHOS | N Gp CIV Other combinations ROX | Homogenate | Drosophila | |
Yamada 2016 J Physiol | 2016 | Yamada T, Takakura H, Jue T, Hashimoto T, Ishizawa R, Furuichi Y, Kato Y, Iwanaka N, Masuda K (2016) Myoglobin and the regulation of mitochondrial respiratory chain complex IV. J Physiol 594:483-95. | LEAK OXPHOS | N S CIV Other combinations ROX | Mouse | Skeletal muscle Other cell lines | |
Birkenmeier 2016 Int J Cancer | 2016 | Birkenmeier Katrin, Droese Stefan, Wittig Ilka, Winkelmann Ria, Kaefer Viktoria, Doering Claudia, Hartmann Sylvia, Wenz Tina, Reichert Andreas S, Brandt Ulrich, Hansmann Martin‐Leo (2016) Hodgkin and Reed-Sternberg cells of classical Hodgkin lymphoma are highly dependent on oxidative phosphorylation. Int J Cancer 138:2231-46. | LEAK ROUTINE ET | ROX | Intact cells | Human | Other cell lines HeLa Macrophage-derived |
Silva 2016 Thesis | 2016 | Silva Luana Caroline Schüeler da (2016) Fucoxantina inibe a oxidação de LDL e ativação de macrófagos in vitro. PhD Thesis:93 pp. | LEAK ROUTINE ET | ROX | Intact cells | Human | |
Singh 2016 Mol Neurobiol | 2016 | Singh N, Hroudová J, Fišar Z (2016) In vitro effects of cognitives and nootropics on mitochondrial respiration and monoamine oxidase activity. Mol Neurobiol 54:5894-904. | LEAK | N S ROX | Isolated mitochondria | Pig | Nervous system |
Spendiff 2016 J Physiol | 2016 | Spendiff S, Vuda M, Gouspillou G, Aare S, Perez A, Morais JA, Jagoe RT, Filion ME, Glicksman R, Kapchinsky S, MacMillan NJ, Pion CH, Aubertin-Leheudre M, Hettwer S, Correa JA, Taivassalo T, Hepple RT (2016) Denervation drives mitochondrial dysfunction in skeletal muscle of octogenarians. J Physiol 594:7361-79. | OXPHOS LEAK | N CIV NS ROX | Permeabilized tissue | Human Mouse | Skeletal muscle |
Dutra 2016 Acta Trop | 2016 | Dutra FL, Oliveira MM, Santos RS, Silva WS, Alviano DS, Vieira DP, Lopes AH (2016) Effects of linalool and eugenol on the survival of Leishmania (L.) infantum chagasi within macrophages. Acta Trop 164:69-76. | ROUTINE | ROX | Intact organism Intact cells | Protists | |
Strecker 2016 Biochim Biophys Acta | 2016 | Strecker V, Kadeer Z, Heidler J, Cruciat CM, Angerer H, Giese H, Pfeiffer K, Stuart RA, Wittig I (2016) Supercomplex-associated Cox26 protein binds to cytochrome c oxidase. Biochim Biophys Acta 1863:1643-52. | ROUTINE ET | ROX | Intact cells | Saccharomyces cerevisiae | |
Gerber 2016 J Med Genet | 2016 | Gerber S, Ding MG, Gérard X, Zwicker K, Zanlonghi X, Rio M, Serre V, Hanein S, Munnich A, Rotig A, Bianchi L, Amati-Bonneau P, Elpeleg O, Kaplan J, Brandt U, Rozet JM (2016) Compound heterozygosity for severe and hypomorphic NDUFS2 mutations cause non-syndromic LHON-like optic neuropathy. J Med Genet 54:346-56. | LEAK ROUTINE ET | ROX | Intact cells | Human | Endothelial;epithelial;mesothelial cell Fibroblast |
Eisenberg 2016 Nat Med | 2016 | Eisenberg T, Abdellatif M, Schroeder S, Primessnig U, Stekovic S, Pendl T, Harger A, Schipke J, Zimmermann A, Schmidt A, Tong M, Ruckenstuhl C, Dammbrueck C, Gross AS, Herbst V, Magnes C, Trausinger G, Narath S, Meinitzer A, Hu Z, Kirsch A, Eller K, Carmona-Gutierrez D, Büttner S, Pietrocola F, Knittelfelder O, Schrepfer E, Rockenfeller P, Simonini C, Rahn A, Horsch M, Moreth K, Beckers J, Fuchs H, Gailus-Durner V, Neff F, Janik D, Rathkolb B, Rozman J, de Angelis MH, Moustafa T, Haemmerle G, Mayr M, Willeit P, von Frieling-Salewsky M, Pieske B, Scorrano L, Pieber T, Pechlaner R, Willeit J, Sigrist SJ, Linke WA, Mühlfeld C, Sadoshima J, Dengjel J, Kiechl S, Kroemer G, Sedej S, Madeo F (2016) Cardioprotection and lifespan extension by the natural polyamine spermidine. Nat Med 22:1428-38. | LEAK ET OXPHOS | N ROX | Isolated mitochondria | Mouse | Heart |
Safiedeen 2016 Antioxid Redox Signal | 2016 | Safiedeen Z, Rodríguez-Gómez I, Vergori L, Soleti R, Vaithilingam D, Douma I, Agouni A, Leiber D, Dubois S, Simard G, Zibara K, Andriantsitohaina R, Martínez MC (2016) Temporal cross talk between endoplasmic reticulum and mitochondria regulates oxidative stress and mediates microparticle-induced endothelial dysfunction. Antioxid Redox Signal 26:15-27. | LEAK ET ROUTINE | ROX | Intact cells | Human | Endothelial;epithelial;mesothelial cell |
Giraldos Jimenez 2016 Thesis | 2016 | Giraldos Jiménez D (2016) Oxidative phosphorylation system’s role in adipogenic differentiation. Thesis p25. | LEAK ROUTINE | ROX | |||
Chakraborty 2016 Pancreatology | 2016 | Chakraborty M, Hickey AJ, Petrov MS, Macdonald JR, Thompson N, Newby L, Sim D, Windsor JA, Phillips AR (2016) Mitochondrial dysfunction in peripheral blood mononuclear cells in early experimental and clinical acute pancreatitis. Pancreatology 16:739-47. | LEAK OXPHOS ROUTINE ET | N Gp CIV NS ROX S | Permeabilized cells | Human Rat | Blood cells |
Fisar 2016a Folia Biol (Praha) | 2016 | Fisar Z, Hroudova J (2016) Pig brain mitochondria as a biological model for study of mitochondrial respiration. Folia Biol (Praha) 62:15-25. | LEAK OXPHOS ET | N S NS ROX | Isolated mitochondria | Pig | Nervous system |
Nauta 2016 Thesis | 2016 | Nauta TD (2016) HIF-2α regulates in vitro neovascularization during hypoxia. Doctoral Dissertation p206. | LEAK ROUTINE ET | ROX | Intact cells | Human | Endothelial;epithelial;mesothelial cell |
Mesquita 2016 Thesis | 2016 | Mesquita Rodrigues C (2016) Efeito da depleção de ferro sobre Leishmania (Viannia) braziliensisuma análise ultraestrutural, proteômica e interação com matrizes de colágeno sintéticas. Doctoral Dissertation p210. | ROUTINE | ROX | Intact cells | Protists | |
Berressem 2016 PLOS ONE | 2016 | Berressem D, Koch K, Franke N, Klein J, Eckert GP (2016) Intravenous treatment with a long-chain omega-3 lipid emulsion provides neuroprotection in a murine model of ischemic stroke - a pilot study. PLOS ONE 11:e0167329. | LEAK OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Mouse | Nervous system |
Grundmanova 2016 Physiol Res | 2016 | Grundmanová M, Jarkovská D, Süß A, Tůma Z, Marková M, Grundman Z, El-Kadi A, Čedíková M, Štengl M, Kuncová J (2016) Propofol-induced mitochondrial and contractile dysfunction of the rat ventricular myocardium. Physiol Res 65:S601-9. | LEAK OXPHOS | N S CIV NS ROX | Permeabilized tissue | Rat | Heart |
Scott 2016 Thesis | 2016 | Scott KY (2016) Evaluation of cardiac mitochondrial function in the fructose-fed rat. Master's Thesis p98. | LEAK OXPHOS ET | F N S CIV ROX | Isolated mitochondria | Rat | Heart |
Schaefer 2016 PLOS ONE | 2016 | Schaefer PM, von Einem B, Walther P, Calzia E, von Arnim CA (2016) Metabolic characterization of intact cells reveals intracellular amyloid beta but not its precursor protein to reduce mitochondrial respiration. PLOS ONE 11:e0168157. | LEAK ROUTINE ET | CIV ROX | Intact cells | Human Mouse | Nervous system HEK |
Chubanov 2016 Elife | 2016 | Chubanov V, Ferioli S, Wisnowsky A, Simmons DG, Leitzinger C, Einer C, Jonas W, Shymkiv Y, Bartsch H, Braun A, Akdogan B, Mittermeier L, Sytik L, Torben F, Jurinovic V, van der Vorst EP, Weber C, Yildirim ÖA, Sotlar K, Schürmann A, Zierler S, Zischka H, Ryazanov AG, Gudermann T (2016) Epithelial magnesium transport by TRPM6 is essential for prenatal development and adult survival. Elife 5. pii: e20914. | ROUTINE ET | ROX | Intact cells | Human | Fibroblast Other cell lines |
Van Hoose 2016 J Nutr Biochem | 2016 | Van Hoose PM, Kelm NQ, Piell KM, Cole MP (2016) Conjugated linoleic acid and nitrite attenuate mitochondrial dysfunction during myocardial ischemia. J Nutr Biochem 34:8-16. | LEAK OXPHOS ET | N ROX | Isolated mitochondria | Mouse | Heart |
Bastow 2016 J Cell Sci | 2016 | Bastow EL, Peswani AR, Tarrant DS, Pentland DR, Chen X, Morgan A, Staniforth GL, Tullet JM, Rowe ML, Howard MJ, Tuite MF, Gourlay CW (2016) New links between SOD1 and metabolic dysfunction from a yeast model of amyotrophic lateral sclerosis. J Cell Sci 129:4118-29. | LEAK ROUTINE ET | ROX | Intact cells | Saccharomyces cerevisiae | |
Berger 2016 Nat Commun | 2016 | Berger E, Rath E, Yuan D, Waldschmitt N, Khaloian S, Allgäuer M, Staszewski O, Lobner EM, Schöttl T, Giesbertz P, Coleman OI, Prinz M, Weber A, Gerhard M, Klingenspor M, Janssen KP, Heikenwalder M, Haller D (2016) Mitochondrial function controls intestinal epithelial stemness and proliferation. Nat Commun 7:13171. | LEAK OXPHOS | S ROX | Mouse | Endothelial;epithelial;mesothelial cell | |
Hancock 2016 Amino Acids | 2016 | Hancock CN, Liu W, Alvord WG, Phang JM (2016) Co-regulation of mitochondrial respiration by proline dehydrogenase/oxidase and succinate. Amino Acids 48:859-72. | LEAK ROUTINE ET | S Other combinations ROX | Isolated mitochondria Oxidase;biochemical oxidation Intact cells | Mouse | Liver |
Kang 2016 Elife | 2016 | Kang Y, Baker MJ, Liem M, Louber J, McKenzie M, Atukorala I, Ang CS, Keerthikumar S, Mathivanan S, Stojanovski D (2016) Tim29 is a novel subunit of the human TIM22 translocase and is involved in complex assembly and stability. Elife 5:e17463. | ROUTINE ET | ROX | Intact cells | Human | |
Galli 2016 Am J Physiol Regul Integr Comp Physiol | 2016 | Galli GL, Crossley J, Elsey RM, Dzialowski EM, Shiels HA, Crossley DA 2nd (2016) Developmental plasticity of mitochondrial function in American alligators, Alligator mississippiensis. Am J Physiol Regul Integr Comp Physiol 311:R1164-72. | LEAK OXPHOS ET | N S CIV Other combinations ROX | Isolated mitochondria | Reptiles | Heart |
Karlsson 2016 Mitochondrion | 2016 | Karlsson M, Ehinger JK, Piel S, Sjövall F, Henriksnäs J, Höglund U, Hansson MJ, Elmér E (2016) Changes in energy metabolism due to acute rotenone-induced mitochondrial complex I dysfunction – an in vivo large animal model. Mitochondrion 31:56-62. | ET | N ROX | Intact cells | Pig | Skeletal muscle Platelet |
Hals 2016 Islets | 2016 | Hals IK, Singh R, Ma Z, Scholz H, Björklund A, Grill V (2016) Culture at low glucose up-regulates mitochondrial function in pancreatic β cells with accompanying effects on viability. Islets 8:165-76. | LEAK ET | ROX | Intact cells | Rat | Islet cell;pancreas;thymus |
Ferguson 2016 J Bioenerg Biomembr | 2016 | Ferguson MA, Sutton RM, Karlsson M, Sjövall F, Becker LB, Berg RA, Margulies SS, Kilbaugh TJ (2016) Increased platelet mitochondrial respiration after cardiac arrest and resuscitation as a potential peripheral biosignature of cerebral bioenergetic dysfunction. J Bioenerg Biomembr 48:269-79. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Homogenate Intact cells | Pig | Nervous system Platelet |
Maarman 2016 J Appl Physiol (1985) | 2016 | Maarman GJ, Andrew BM, Blackhurst DM, Ojuka EO (2016) Melatonin protects against uric acid-induced mitochondrial dysfunction, oxidative stress, and triglyceride accumulation in C2C12 myotubes. J Appl Physiol (1985) 122:1003-10. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Intact cells | Mouse | Skeletal muscle |
Hartmannova 2016 Hum Mol Genet | 2016 | Hartmannová H, Piherová L, Tauchmannová K, Kidd K, Acott PD, Crocker JF, Oussedik Y, Mallet M, Hodaňová K, Stránecký V, Přistoupilová A, Barešová V, Jedličková I, Živná M, Sovová J, Hůlková H, Robins V, Vrbacký M, Pecina P, Kaplanová V, Houštěk J, Mráček T, Thibeault Y, Bleyer AJ, Kmoch S (2016) Acadian variant of Fanconi syndrome is caused by mitochondrial respiratory chain complex I deficiency due to a non-coding mutation in complex I assembly factor NDUFAF6. Hum Mol Genet 25:4062-79. | LEAK OXPHOS ET | N S Gp CIV NS ROX | Permeabilized cells | Human | Fibroblast |
Dechandt 2016 Anal Biochem | 2016 | Dechandt CRP, Couto-Lima CA, Alberici LC (2016) Triglyceride depletion of brown adipose tissue enables analysis of mitochondrial respiratory function in permeabilized biopsies. Anal Biochem 515:55-60. | LEAK OXPHOS ET | N S ROX | Permeabilized tissue | Rat | Fat |
Salin 2016 Physiol Rep | 2016 | Salin K, Villasevil EM, Auer SK, Anderson GJ, Selman C, Metcalfe NB, Chinopoulos C (2016) Simultaneous measurement of mitochondrial respiration and ATP production in tissue homogenates and calculation of effective P/O ratios. Physiol Rep 10.14814/phy2.13007. | LEAK OXPHOS | N NS ROX | Homogenate | Fishes | Liver |
Reich 2016 Thesis | 2016 | Reich V (2016) Pathophysiologie und Verfahrensentwicklung: Mechanismen der Metabolisierung von Schwefelwasserstoff im mitochondrialen Atmungskreislauf von Lungenalveolarmakrophagen. Dissertation p91. | LEAK OXPHOS ET | N S CIV NS ROX | Intact cells Permeabilized cells | Mouse | Macrophage-derived |
Chowdhury 2015 Biosci Rep | 2016 | Chowdhury SK, Djordjevic J, Albensi B, Fernyhough P (2015) Simultaneous evaluation of substrate-dependent oxygen consumption rates and mitochondrial membrane potential by TMRM and safranin in cortical mitochondria. Biosci Rep 36:e00286. | LEAK OXPHOS ET | N S NS ROX | Homogenate Isolated mitochondria | Mouse | Nervous system |
Speijer 2016 Biochem J | 2016 | Speijer D (2016) Being right on Q: shaping eukaryotic evolution. Biochem J 473:4103-27. | F N ROX | ||||
Perna 2016 Amino Acids | 2016 | Perna MK, Kokenge AN, Miles KN, Udobi KC, Clark JF, Pyne-Geithman GJ, Khuchua Z, Skelton MR (2016) Creatine transporter deficiency leads to increased whole body and cellular metabolism. Amino Acids 48:2057-65. | LEAK OXPHOS ET | N NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
Salvadego 2016 J Appl Physiol (1985) | 2016 | Salvadego D, Keramidas ME, Brocca L, Domenis R, Mavelli I, Rittweger J, Eiken O, Mekjavic IB, Grassi B (2016) Separate and combined effects of a 10-d exposure to hypoxia and inactivity on oxidative function in vivo and mitochondrial respiration ex vivo in humans. J Appl Physiol (1985) 121:154-63. | LEAK OXPHOS ET | N ROX | Permeabilized tissue | Human | Skeletal muscle |
Fonseca-Berzal 2016 Parasitology | 2016 | Fonseca-Berzal C, DA Silva CF, Menna-Barreto RF, Batista MM, Escario JA, Arán VJ, Gómez-Barrio A, Soeiro Mde N (2016) Biological approaches to characterize the mode of action of two 5-nitroindazolinone prototypes on Trypanosoma cruzi bloodstream trypomastigotes. Parasitology 143:1469-78. | ROUTINE | ROX | Intact organism | Protists | |
Docherty 2016 Stem Cell Res Ther | 2016 | Docherty CK, Salt IP, Mercer JR (2016) Lin28A induces energetic switching to glycolytic metabolism in human embryonic kidney cells. Stem Cell Res Ther 7:78. | LEAK ET | ROX | Intact cells | Human | Kidney HEK |
Fisar 2016 Curr Alzheimer Res | 2016 | Fišar Z, Hroudová J, Hansíková H, Spáčilová J, Lelková P, Wenchich L, Jirák R, Zvěřová M, Zeman J, Martásek P, Raboch J (2016) Mitochondrial respiration in the platelets of patients with Alzheimer's disease. Curr Alzheimer Res 13:930-41. | LEAK OXPHOS ET | N S NS ROX | Intact cells Permeabilized cells | Human | Blood cells Platelet |
Fisar 2016b Folia Biol (Praha) | 2016 | Fisar Z, Hroudova J, Singh N, Koprivova A, Maceckova D (2016) Effect of simvastatin, coenzyme Q10, resveratrol, acetylcysteine and acetylcarnitine on mitochondrial respiration. Folia Biol (Praha) 62:53-66. | OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Pig | Nervous system |
Abdel-Rahman 2016 Oxid Med Cell Longev | 2016 | Abdel-Rahman EA, Mokhtar A, Aaliya A, Radwan Y, Yasseen B, Al-Okda A, Atwa A, Elhanafy E, Habashy M, Ali SS (2016) Resolving contributions of oxygen-consuming and ROS-generating enzymes at the synapse. Oxid Med Cell Longev p19. | LEAK OXPHOS | N NS ROX | Permeabilized cells | Mouse | Nervous system |
Macheiner 2016 Sci Rep | 2016 | Macheiner T, Fengler VH, Agreiter M, Eisenberg T, Madeo F, Kolb D, Huppertz B, Ackbar R, Sargsyan K (2016) Magnetomitotransfer: An efficient way for direct mitochondria transfer into cultured human cells. Sci Rep 6:35571. | LEAK ROUTINE ET | ROX | Human | Fibroblast Lung;gill | |
Ruiz 2016 J Photochem Photobiol B | 2016 | Ruiz VE, Interdonato R, Cerioni L, Albornoz P, Ramallo J, Prado FE, Hilal M, Rapisarda VA (2016) Short-term UV-B exposure induces metabolic and anatomical changes in peel of harvested lemons contributing in fruit protection against green mold. J Photochem Photobiol B 159:59-65. | CIV ROX | Intact cells | Plants | ||
Davuluri 2016 J Physiol | 2016 | Davuluri G, Allawy A, Thapaliya S, Rennison JH, Singh D, Kumar A, Sandlers Y, Van Wagoner DR, Flask CA, Hoppel C, Kasumov T, Dasarathy S (2016) Hyperammonaemia-induced skeletal muscle mitochondrial dysfunction results in cataplerosis and oxidative stress. J Physiol 594:7341-60. | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Skeletal muscle Other cell lines |
Pohland 2016 Neurochem Res | 2016 | Pohland M, Hagl S, Pellowska M, Wurglics M, Schubert-Zsilavecz M, Eckert GP (2016) MH84: a novel γ-secretase modulator/PPARγ agonist-improves mitochondrial dysfunction in a cellular model of Alzheimer's disease. Neurochem Res 41:231-42. | LEAK OXPHOS ET | N S CIV NS ROX | Permeabilized cells | Human | Kidney HEK |
Asseburg 2016 Neuromolecular Med | 2016 | Asseburg H, Schäfer C, Müller M, Hagl S, Pohland M, Berressem D, Borchiellini M, Plank C, Eckert GP (2016) Effects of grape skin extract on age-related mitochondrial dysfunction, memory and life span in C57BL/6J mice. Neuromolecular Med 18:378-95. | LEAK OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Mouse | Nervous system |
Svenkrtova 2016 Biogerontology | 2016 | Svenkrtova A, Belicova L, Volejnikova A, Sigler K, Jazwinski SM, Pichova A (2016) Stratification of yeast cells during chronological aging by size points to the role of trehalose in cell vitality. Biogerontology 17:395-408. | ROUTINE | CIV ROX | Intact cells | Saccharomyces cerevisiae | |
Salin 2016 Physiol Biochem Zool | 2016 | Salin K, Auer SK, Rudolf AM, Anderson GJ, Selman C, Metcalfe NB (2016) Variation in metabolic rate among individuals is related to tissue-specific differences in mitochondrial LEAK respiration. Physiol Biochem Zool 89:511-23. | LEAK OXPHOS | N CIV NS ROX | Homogenate | Fishes | Skeletal muscle Liver |
Nissinen 2016 Sci Rep | 2016 | Nissinen TA, Degerman J, Räsänen M, Poikonen AR, Koskinen S, Mervaala E, Pasternack A, Ritvos O, Kivelä R, Hulmi JJ (2016) Systemic blockade of ACVR2B ligands prevents chemotherapy-induced muscle wasting by restoring muscle protein synthesis without affecting oxidative capacity or atrogenes. Sci Rep 6:32695. | LEAK OXPHOS ET | N S CIV NS ROX | Homogenate | Mouse | Skeletal muscle |
Queliconi 2016 PLOS ONE | 2016 | Queliconi BB, Kowaltowski AJ, Gottlieb RA (2016) Bicarbonate increases ischemia-reperfusion damage by inhibiting mitophagy. PLOS ONE 11:e0167678. | LEAK OXPHOS ET | S ROX | Isolated mitochondria | Rat | Heart |
Roempler 2016 J Biol Chem | 2016 | Römpler K, Müller T, Juris L, Wissel M, Vukotic M, Hofmann K, Deckers M (2016) Overlapping role of respiratory supercomplex factor Rcf2 and its N-terminal homolog Rcf3 in Saccharomyces cerevisiae. J Biol Chem 291:23769-78. | LEAK OXPHOS | N CIV NS ROX | Isolated mitochondria | Saccharomyces cerevisiae | |
Tyrrell 2016 Redox Biol | 2016 | Tyrrell DJ, Bharadwaj MS, Jorgensen MJ, Register TC, Molina AJ (2016) Blood cell respirometry is associated with skeletal and cardiac muscle bioenergetics: Implications for a minimally invasive biomarker of mitochondrial health. Redox Biol 10:65-77. https://doi.org/10.1016/j.redox.2016.09.009 | OXPHOS LEAK ET | N NS ROX | Permeabilized tissue Isolated mitochondria Intact cells | Other mammals Human | Skeletal muscle Blood cells Platelet |
Du 2016 Thesis | 2016 | Du X (2016) Anthropogenic pollution effects on mitochondrial energy metabolism, gene expression, and genotypes of natural Fundulus heteroclitus populations. Dissertation p175. | LEAK OXPHOS ET | S CIV ROX N NS | Permeabilized cells | Fishes | Liver |
Chen 2016 Nat Chem Biol | 2016 | Chen YJ, Mahieu NG, Huang X, Singh M, Crawford PA, Johnson SL, Gross RW, Schaefer J, Patti GJ (2016) Lactate metabolism is associated with mammalian mitochondria. Nat Chem Biol 12:937-43. | LEAK OXPHOS ET | N NS ROX | Isolated mitochondria | Human | HeLa |
Drehmer 2016 Stem Cell Res | 2016 | Drehmer DL, de Aguiar AM, Brandt AP, Petiz L, Cadena SM, Rebelatto CK, Brofman PR, Filipak Neto F, Dallagiovanna B, Abud AP (2016) Metabolic switches during the first steps of adipogenic stem cells differentiation. Stem Cell Res 17:413-421. | LEAK ROUTINE ET | ROX | Intact cells | Human | Fat Stem cells |
Scialo 2016 PLOS ONE | 2016 | Scialo F, Sriram A, Stefanatos R, Sanz A (2016) Practical recommendations for the use of the GeneSwitch Gal4 system to knock-Down genes in Drosophila melanogaster. PLOS ONE 11:e0161817. | LEAK OXPHOS | N CIV Other combinations ROX Gp | Homogenate | Drosophila | |
Villani 2016 Mol Metab | 2016 | Villani LA, Smith BK, Marcinko K, Ford RJ, Broadfield LA, Green AE, Houde VP, Muti P, Tsakiridis T, Steinberg GR (2016) The diabetes medication Canagliflozin reduces cancer cell proliferation by inhibiting mitochondrial complex-I supported respiration. Mol Metab 5:1048-56. | OXPHOS | N S ROX | Permeabilized cells | Human | Genital |
Smith 2016 Diabetes | 2016 | Smith BK, Ford RJ, Desjardins EM, Green AE, Hughes MC, Houde VP, Day EA, Marcinko K, Crane JD, Mottillo EP, Perry CG, Kemp BE, Tarnopolsky MA, Steinberg GR (2016) Salsalate (Salicylate) uncouples mitochondria, improves glucose homeostasis, and reduces liver lipids independent of AMPK β1. Diabetes 65:3352-61. | LEAK OXPHOS ET | F N NS Other combinations ROX | Permeabilized cells Isolated mitochondria Permeabilized tissue | Mouse | Skeletal muscle Liver Fat |
Baris 2016 Am J Physiol Regul Integr Comp Physiol | 2016 | Baris TZ, Blier PU, Pichaud N, Crawford DL, Oleksiak MF (2016) Gene by environmental interactions affecting oxidative phosphorylation and thermal sensitivity. Am J Physiol Regul Integr Comp Physiol 311:R157-65. | LEAK OXPHOS ET | CIV NS ROX S | Permeabilized tissue | Fishes | Heart |
Timpani 2016 Neurotherapeutics | 2016 | Timpani CA, Trewin AJ, Stojanovska V, Robinson A, Goodman CA, Nurgali K, Betik AC, Stepto N, Hayes A, McConell GK, Rybalka E (2016) Attempting to compensate for reduced neuronal nitric oxide synthase protein with nitrate supplementation cannot overcome metabolic dysfunction but rather has detrimental effects in Dystrophin-deficient mdx muscle. Neurotherapeutics 14:429-46. | LEAK OXPHOS ET | N CIV NS Other combinations ROX S | Permeabilized tissue | Mouse | Skeletal muscle |
Briston 2016 Sci Rep | 2016 | Briston T, Lewis S, Koglin M, Mistry K, Shen Y, Hartopp N, Katsumata R, Fukumoto H, Duchen MR, Szabadkai G, Staddon JM, Roberts M, Powney B (2016) Identification of ER-000444793, a Cyclophilin D-independent inhibitor of mitochondrial permeability transition, using a high-throughput screen in cryopreserved mitochondria. Sci Rep 6:37798. | LEAK OXPHOS ET | N S ROX | Isolated mitochondria | Rat | Liver |
Witt 2016 Metab Brain Dis | 2016 | Witt AM, Larsen FS, Bjerring PN (2016) Accumulation of lactate in the rat brain during hyperammonaemia is not associated with impaired mitochondrial respiratory capacity. Metab Brain Dis 32:461-70. | LEAK OXPHOS ET | N S NS ROX | Homogenate | Rat | Nervous system |
Pambianco 2016 Cell Rep | 2016 | Pambianco S, Giovarelli M, Perrotta C, Zecchini S, Cervia D3, Di Renzo I, Moscheni C, Ripolone M, Violano R, Moggio M, Bassi MT, Puri PL, Latella L, Clementi E, De Palma C (2016) Reversal of defective mitochondrial biogenesis in limb-girdle muscular dystrophy 2D by independent modulation of histone and PGC-1α acetylation. Cell Rep 17:3010-23. | LEAK OXPHOS | F N S NS ROX | Permeabilized cells Isolated mitochondria Permeabilized tissue | Mouse | Skeletal muscle |
Valek 2016 Redox Biol | 2016 | Valek L, Häussler A, Dröse S, Eaton P, Schröder K, Tegeder I (2016) Redox-guided axonal regrowth requires cyclic GMP dependent protein kinase 1: Implication for neuropathic pain. Redox Biol 11:176-91. | OXPHOS LEAK | N S CIV ROX | Homogenate | Mouse | Nervous system |
Strifler 2016b PLOS ONE | 2016 | Strifler G, Tuboly E, Görbe A, Boros M, Pécz D, Hartmann P (2016) Targeting mitochondrial dysfunction with L-alpha glycerylphosphorylcholine. PLOS ONE 11:e0166682. | LEAK OXPHOS ET | N S NS Other combinations ROX | Homogenate | Rat | Liver |
Torres 2016 Redox Biol | 2016 | Torres S, Matías N, Baulies A, Nuñez S, Alarcon-Vila C, Martinez L, Nuño N, Fernandez A, Caballeria J, Levade T, Gonzalez-Franquesa A, Garcia-Rovés P, Balboa E, Zanlungo S, Fabrías G, Casas J, Enrich C, Garcia-Ruiz C, Fernández-Checa JC (2016) Mitochondrial GSH replenishment as a potential therapeutic approach for Niemann Pick type C disease. Redox Biol 11:60-72. | LEAK ROUTINE OXPHOS ET | N S ROX | Homogenate Intact cells | Human Mouse | Nervous system Liver Endothelial;epithelial;mesothelial cell Fibroblast |
Heimer 2016 Am J Hum Genet | 2016 | Heimer G, Kerätär JM, Riley LG, Balasubramaniam S, Eyal E, Pietikäinen LP, Hiltunen JK, Marek-Yagel D, Hamada J, Gregory A, Rogers C, Hogarth P, Nance MA, Shalva N, Veber A, Tzadok M, Nissenkorn A, Tonduti D, Renaldo F, Kraoua I, Panteghini C, Valletta L, Garavaglia B, Cowley MJ, Gayevskiy V, Roscioli T, Silberstein JM, Hoffmann C, Raas-Rothschild A, Tiranti V, Anikster Y, Christodoulou J, Kastaniotis AJ, Ben-Zeev B, Hayflick SJ (2016) MECR mutations cause childhood-onset dystonia and optic atrophy, a mitochondrial fatty acid synthesis disorder. Am J Hum Genet 99:1229-44. | LEAK ROUTINE ET | ROX | Intact cells | Human | Fibroblast |
Strifler 2016 Magyar Sebeszet | 2016 | Strifler G, Meszaros A, Pecz D, Ficzere A, Barath B, Mihaly B, Hartmann P (2016) A májfunkció vizsgálata respirometriával - Examination of liver mitochondria with respirometry. Magyar Sebészet 69:194–8. | OXPHOS LEAK | N S CIV NS ROX Other combinations | Homogenate | Rat | Liver |
Loureiro 2016 Oxid Med Cell Longev | 2016 | Loureiro AC, do Rêgo-Monteiro IC, Louzada RA, Ortenzi VH, de Aguiar AP, de Abreu ES, Cavalcanti-de-Albuquerque JP, Hecht F, de Oliveira AC, Ceccatto VM, Fortunato RS, Carvalho DP (2016) Differential expression of NADPH oxidases depends on skeletal muscle fiber type in rats. Oxid Med Cell Longev 2016:6738701. | LEAK OXPHOS | N CIV NS ROX | Permeabilized tissue | Rat | Skeletal muscle |
Stier 2016 Methods Ecol Evol | 2016 | Stier A, Romestaing C, Schull Q, Lefol E, Robin JP, Roussel D, Bize P (2016) How to measure mitochondrial function in birds using red blood cells: a case study in the king penguin and perspectives in ecology and evolution. Methods Ecol Evol doi:10.1111/2041-210X.12724. | LEAK ROUTINE OXPHOS ET | N S ROX | Permeabilized tissue Intact cells | Birds | Skeletal muscle Blood cells |
Brecht 2016 Toxicol In Vitro | 2016 | Brecht K, Riebel V, Couttet P, Paech F, Wolf A, Chibout SD, Pognan F, Krähenbühl S, Uteng M (2016) Mechanistic insights into selective killing of OXPHOS-dependent cancer cells by arctigenin. Toxicol In Vitro 40:55-65. | LEAK OXPHOS ET | N S CIV Other combinations ROX DQ | Permeabilized cells | Human | Islet cell;pancreas;thymus |
Moll 2016 bioRxiv | 2016 | Moll CWI, Lindtner RA, Vogel GF, Brunner M, Gutleben K, Blauth M, Krumschnabel G, Ebner HL (2016) Bone marrow mesenchymal stem cells from osteoporotic patients do not show altered mitochondrial energetics or ultrastructure. bioRxiv doi.org/10.1101/046300. | LEAK ROUTINE OXPHOS ET | N S ROX | Intact cells Permeabilized cells | Human | Stem cells |
Yan 2015 BMC Cancer | 2015 | Yan B, Stantic M, Zobalova R, Bezawork-Geleta A, Stapelberg M, Stursa J, Prokopova K, Dong L, Neuzil J (2015) Mitochondrially targeted vitamin E succinate efficiently kills breast tumour-initiating cells in a complex II-dependent manner. BMC Cancer 15:401. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human Mouse | Genital Other cell lines |
Imran 2015 J Neurochem | 2015 | Imran I, Hillert MH, Klein J (2015) Early metabolic responses to lithium/pilocarpine-induced status epilepticus in rat brain. J Neurochem 135:1007-18. | LEAK OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Rat | Nervous system |
Mallick 2015 Cell Calcium | 2015 | Mallick RL, Kumari S, Singh N, Sonkar VK, Dash D (2015) Prion protein fragment (106-126) induces prothrombotic state by raising platelet intracellular calcium and microparticle release. Cell Calcium 57:300-11. | ROUTINE | ROX | Intact cells | Human | Blood cells Platelet |
Ikaga 2015 Biochem Biophys Rep | 2015 | Ikaga R, Namekatac I, Kotiadisd VN, Ogawab H, Duchend MR, Tanakac H, Iida-Tanakab N (2015) Knockdown of aquaporin-8 induces mitochondrial dysfunction in 3T3-L1 cells. Biochem Biophys Rep 4:187–95. | LEAK ROUTINE ET | CIV ROX | Intact cells | Mouse | Fat Other cell lines |
Schwarzkopf 2015 Neuroscience | 2015 | Schwarzkopf TM, Koch K, Klein J (2015) Reduced severity of ischemic stroke and improvement of mitochondrial function after dietary treatment with the anaplerotic substance triheptanoin. Neuroscience 300:201-9. | LEAK OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Mouse | Nervous system |
Wahrheit 2015 Eng Life Sci | 2015 | Wahrheit J, Nonnenmacher Y, Sperber S, Heinzle E (2015) High-throughput respiration screening of single mitochondrial substrates using permeabilized CHO cells highlights control of mitochondria metabolism. Eng Life Sci 15:184-94. | LEAK OXPHOS | N S ROX | Permeabilized cells | Other mammals | Genital |
Cagnone 2015 Methods Mol Biol | 2015 | Cagnone G, Vaghjiani V, Lee W, Sun C, Johnson J, Yeung KY, St John JC (2015) Analysis of the mitochondrial DNA and its replicative capacity in induced pluripotent stem cells. Methods Mol Biol 1357:231-67. | LEAK ROUTINE ET | ROX | Intact cells | Human | Stem cells |
Labieniec-Watala 2015 Int J Pharm Sci Res | 2015 | Labieniec-Watala M, Przygodzki T, Siewiera K, Podsedek A, Watala C (2015) Facts and artifacts in the evaluation of the anti-diabetic activity of spent hop extract in rat hearts in the “experimental model of diabetes. Int J Pharm Sci Res 1:106. | LEAK OXPHOS ET | S ROX | Isolated mitochondria | Rat | Heart |
Lourenco 2015 Front Aging Neurosci | 2015 | Lourenço CF, Ledo A, Dias C, Barbosa RM, Laranjinha J (2015) Neurovascular and neurometabolic derailment in aging and Alzheimer's disease. Front Aging Neurosci 7:103. | ROUTINE ET | ROX | Intact cells | Mouse | Nervous system |
Kluckova 2015 Cell Death Dis | 2015 | Kluckova K, Sticha M, Cerny J, Mracek T, Dong L, Drahota Z, Gottlieb E, Neuzil J, Rohlena J (2015) Ubiquinone-binding site mutagenesis reveals the role of mitochondrial complex II in cell death initiation. Cell Death Dis 6:e1749. | OXPHOS ET | S ROX | Permeabilized cells Isolated mitochondria | Other mammals | Lung;gill Other cell lines Fibroblast |
Rovenko 2015 Comp Biochem Physiol A Mol Integr Physiol | 2015 | Rovenko BM, Kubrak OI, Gospodaryov DV, Yurkevych IS, Sanz A, Lushchak OV, Lushchak VI (2015) Restriction of glucose and fructose causes mild oxidative stress independently of mitochondrial activity and reactive oxygen species in Drosophila melanogaster. Comp Biochem Physiol A Mol Integr Physiol 187:27-39. | OXPHOS | N Gp CIV Other combinations ROX | Homogenate | Drosophila | |
Park 2015 Proc Natl Acad Sci USA | 2015 | Park JH, Kang HJ, Lee YK, Kang H, Kim J, Chung JH, Chang JS, McPherron AC, Lee SB (2015) Inactivation of EWS reduces PGC-1α protein stability and mitochondrial homeostasis. Proc Natl Acad Sci USA 112:6074-9. | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Fat |
Blatzer 2015 Antioxid Redox Signal | 2015 | Blatzer M, Jukic E, Posch W, Schöpf B, Binder U, Steger M, Blum G, Hackl H, Gnaiger E, Lass-Flörl C, Wilflingseder D (2015) Amphotericin B resistance in Aspergillus terreus is overpowered by co-application of pro-oxidants. Antioxid Redox Signal 23:1424-38. https://doi.org/10.1089/ars.2014.6220 | ROUTINE | ROX | Intact cells | Fungi | |
Koliaki 2015 Cell Metab | 2015 | Koliaki C, Szendroedi J, Kaul K, Jelenik T, Nowotny P, Jankowiak F, Herder C, Carstensen M, Krausch M, Knoefel WT, Schlensak M, Roden M (2015) Adaptation of hepatic mitochondrial function in humans with non-alcoholic fatty liver is lost in steatohepatitis. Cell Metab 21:739-46. | LEAK OXPHOS ET | F N NS Other combinations ROX | Homogenate Isolated mitochondria | Human | Liver |
Smolkova 2015 Int J Biochem Cell Biol | 2015 | Smolková K, Dvořák A, Zelenka J, Vítek L, Ježek P (2015) Reductive carboxylation and 2-hydroxyglutarate formation by wild-type IDH2 in breast carcinoma cells. Int J Biochem Cell Biol 65:125-33. | LEAK ROUTINE ET | ROX | Intact cells | Human | Endothelial;epithelial;mesothelial cell Other cell lines |
Kilbaugh 2015 Exp Neurol | 2015 | Kilbaugh TJ, Karlsson M, Byro M, Bebee A, Ralston J, Sullivan S, Duhaime AC, Hansson MJ, Elmér E, Margulies SS (2015) Mitochondrial bioenergetic alterations after focal traumatic brain injury in the immature brain. Exp Neurol 271:136-144. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized tissue Homogenate | Pig | Nervous system |
Hwang 2015 EMBO Mol Med | 2015 | Hwang S, Disatnik MH, Mochly-Rosen D (2015) Impaired GAPDH-induced mitophagy contributes to the pathology of Huntington's disease. EMBO Mol Med 7:1307-26. | LEAK OXPHOS ET | ROX | Intact cells | Rat | Nervous system Other cell lines |
Houben 2015 Mitochondrion | 2015 | Houben R, Leleu C, Fraipont A, Serteyn D, Votion DM (2015) Determination of muscle mitochondrial respiratory capacity in Standardbred racehorses as an aid to predicting exertional rhabdomyolysis. Mitochondrion 24:99-104. | OXPHOS ET | N S NS ROX | Permeabilized tissue | Horse | Skeletal muscle |
Ramos-Filho 2015 PLoS One | 2015 | Ramos-Filho D, Chicaybam G, de-Souza-Ferreira E, Guerra Martinez C, Kurtenbach E, Casimiro-Lopes G, Galina A (2015) High intensity interval training (HIIT) induces specific changes in respiration and electron leakage in the mitochondria of different rat skeletal muscles. PLoS One 10:e0131766. | LEAK OXPHOS ET | F N S Gp NS ROX | Permeabilized tissue | Rat | Skeletal muscle |
Larsen 2015 Physiol Rep | 2015 | Larsen S, Scheede-Bergdahl C, Whitesell T, Boushel R, Bergdahl A (2015) Increased intrinsic mitochondrial respiratory capacity in skeletal muscle from rats with streptozotocin-induced hyperglycemia. Physiol Rep 3 pii:e12467. | LEAK OXPHOS | F N CIV NS Other combinations ROX | Permeabilized tissue | Rat | Skeletal muscle |
Schoettl 2015 Mol Metab | 2015 | Schöttl T, Kappler L, Fromme T, Klingenspor M (2015) Limited OXPHOS capacity in white adipocytes is a hallmark of obesity in laboratory mice irrespective of the glucose tolerance status. Mol Metab 4:631-42. | LEAK ROUTINE OXPHOS ET | F N S ROX | Isolated mitochondria Intact cells | Mouse | Fat Other cell lines |
Sundstroem 2015 PhD Thesis | 2015 | Sundstrøm T (2015) Experimental modeling and novel therapeutic strategies in melanoma brain metastasis. PhD Thesis 1-146. | ET | N S NS ROX | Mouse | Nervous system | |
Correa 2015 Critical Care Horizon | 2015 | Corrêa TD, Jakob SM, Takala J (2015) Mitochondrial function in sepsis. Critical Care Horizon 1:31-41 . | LEAK OXPHOS | N S CIV ROX | Isolated mitochondria | Pig | Liver |
Dueregger 2015 PLoS One | 2015 | Dueregger A, Schöpf B, Eder T, Höfer J, Gnaiger E, Aufinger A, Kenner L, Perktold B, Ramoner R, Klocker H, Eder IE (2015) Differential utilization of dietary fatty acids in benign and malignant cells of the prostate. PLoS One 10(8):e0135704. | LEAK ROUTINE OXPHOS ET | F N NS ROX | Permeabilized cells Permeabilized tissue | Human | Genital Other cell lines |
Grevengoed 2015 J Lipid Res | 2015 | Grevengoed TJ, Martin SA, Katunga L, Cooper DE, Anderson EJ, Murphy RC, Coleman RA (2015) Acyl-CoA synthetase 1 deficiency alters cardiolipin species and impairs mitochondrial function. J Lipid Res 56:1572-82. | LEAK OXPHOS | F N NS ROX | Permeabilized tissue | Mouse | Heart Other cell lines HEK |
Johnson 2015 Aging Cell | 2015 | Johnson ML, Lalia AZ, Dasari S, Pallauf M, Fitch M, Hellerstein MK, Lanza IR (2015) Eicosapentaenoic acid but not docosahexaenoic acid restores skeletal muscle mitochondrial oxidative capacity in old mice. Aging Cell 14:734-43. | LEAK OXPHOS | F N S NS ROX | Isolated mitochondria | Mouse | Skeletal muscle |
Du 2015 Aquat Toxicol | 2015 | Du X, Crawford DL, Oleksiak MF (2015) Effects of anthropogenic pollution on the oxidative phosphorylation pathway of hepatocytes from natural populations of Fundulus heteroclitus. Aquat Toxicol 165:231-40. | LEAK OXPHOS ET | N S CIV ROX | Permeabilized cells | Fishes | Liver |
Gainutdinov 2015 Arch Biochem Biophys | 2015 | Gainutdinov T, Molkentin JD, Siemen D, Ziemer M, Debska-Vielhaber G, Vielhaber S, Gizatullina Z, Orynbayeva Z, Gellerich FN (2015) Knockout of cyclophilin D in Ppif(-/-) mice increases stability of brain mitochondria against Ca(2+) stress. Arch Biochem Biophys 579:40-6. | LEAK OXPHOS | N S ROX | Isolated mitochondria | Mouse | Nervous system |
Kelly 2015 Biotechnol J | 2015 | Kelly PS, Breen L, Gallagher C, Kelly S, Henry M, Lao NT, Meleady P, O'Gorman D, Clynes M, Barron N (2015) Re-programming CHO cell metabolism using miR-23 tips the balance towards a highly productive phenotype. Biotechnol J 10:1029-40. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Intact cells Permeabilized cells | CHO | |
Orynbayeva 2015 Nanomedicine (Lond) | 2015 | Orynbayeva Z, Sensenig R, Polyak B (2015) Metabolic and structural integrity of magnetic nanoparticle-loaded primary endothelial cells for targeted cell therapy. Nanomedicine (Lond) 10:1555-68. | LEAK ROUTINE ET | ROX | Intact cells | Rat | Endothelial;epithelial;mesothelial cell |
Singh 2015 Free Radic Biol Med | 2015 | Singh P, Sharma R, McElhanon K, Allen CD, Megyesi JK, Beneš H, Singh SP (2015) Sulforaphane protects the heart from doxorubicin-induced toxicity. Free Radic Biol Med 86:90-101. | OXPHOS | N S CIV ROX | Permeabilized tissue | Mouse | Heart Other cell lines |
Boerma 2015 Radiat Res | 2015 | Boerma M, Singh P, Sridharan V, Tripathi P, Sharma S, Singh SP (2015) Effects of local heart irradiation in a glutathione S-transferase alpha 4-null mouse model. Radiat Res 183:610-9. | OXPHOS | N S CIV ROX | Permeabilized tissue | Mouse | Heart |
Cahill 2015 J Biol Chem | 2015 | Cahill TJ, Leo V, Kelly M, Stockenhuber A, Kennedy NW, Bao L, Cereghetti G, Harper AR, Czibik G, Lao C, Bellahcene M, Steeples V, Ghaffari S, Yavari A, Mayer A, Poulton J, Ferguson D, Scorrano L, Hettiarachchi NT, Peers C, Boyle J, Hill RB, Simmons A, Watkins H, Dear TN, Ashrafian H (2015) Resistance of dynamin-related protein 1 oligomers to disassembly impairs mitophagy resulting in myocardial inflammation and heart failure. J Biol Chem 290:25907-19. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Mouse | Heart |
Konopka 2015 Diabetes | 2015 | Konopka AR, Asante A, Lanza IR, Robinson MM, Johnson ML, Dalla Man C, Cobelli C, Amols MH, Irving BA, Nair KS (2015) Defects in mitochondrial efficiency and H2O2 emissions in obese women are restored to a lean phenotype with aerobic exercise training. Diabetes 64:2104-15. | LEAK OXPHOS ET | N S NS ROX | Isolated mitochondria | Human | Skeletal muscle |
Kluckova 2015 Methods Mol Biol | 2015 | Kluckova K, Dong L, Bajzikova M, Rohlena J, Neuzil J (2015) Evaluation of respiration of mitochondria in cancer cells exposed to mitochondria-targeted agents. Methods Mol Biol 1265:181-94. | LEAK OXPHOS ET | N S NS ROX | Permeabilized cells Homogenate Intact cells | Mouse | Endothelial;epithelial;mesothelial cell Genital Other cell lines |
Hendricks 2015 Thesis | 2015 | Hendricks EW (2015) The impact of aging and estrogen therapy on synaptic mitochondrial bioenergetics in an Alzheimer's mouse model. Master Thesis 1-67. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Isolated mitochondria Intact cells | Mouse | Nervous system |
Vincent 2015 Front Physiol | 2015 | Vincent G, Lamon S, Gant N, Vincent PJ, MacDonald JR, Markworth JF, Edge JA, Hickey AJ (2015) Changes in mitochondrial function and mitochondria associated protein expression in response to 2-weeks of high intensity interval training. Front Physiol 6:51. | LEAK OXPHOS ET | N S ROX | Permeabilized tissue | Human | Skeletal muscle |
Ping 2015 Oxid Med Cell Longev | 2015 | Ping Z, Zhang LF, Cui YJ, Chang YM, Jiang CW, Meng ZZ, Xu P, Liu HY, Wang DY, Cao XB (2015) The protective effects of Salidroside from exhaustive exercise-induced heart injury by enhancing the PGC-1𝛼–NRF1/NRF2 pathway and mitochondrial respiratory function in rats. Oxid Med Cell Longev Article ID 876825. | OXPHOS ET | N S CIV ROX | Permeabilized tissue | Rat | Heart |
Hasli 2015 Master Thesis | 2015 | Hasli PR (2015) Characterization of mitochondrial respiration and quality differences in diploid and triploid Atlantic salmon (Salmo salar L.) at 5 °C, 10 °C and 15 °C. Master Thesis:1-147. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue Homogenate | Fishes | Heart Skeletal muscle |
Cell ergometry | 2015 | Gnaiger E (2015) Cell ergometry and OXPHOS. Mitochondr Physiol Network 2015-01-18. | LEAK OXPHOS ET | N S NS ROX | |||
Krumschnabel 2015 Methods Mol Biol | 2015 | Krumschnabel G, Fontana-Ayoub M, Sumbalova Z, Heidler J, Gauper K, Fasching M, Gnaiger E (2015) Simultaneous high-resolution measurement of mitochondrial respiration and hydrogen peroxide production. Methods Mol Biol 1264:245-61. | LEAK OXPHOS ET | N S NS ROX | Isolated mitochondria | Mouse | Nervous system |
Rodrigues 2015 J Cell Biochem | 2015 | Rodrigues MF, Carvalho É, Pezzuto P, Rumjanek FD, Amoêdo ND (2015) Reciprocal modulation of histone deacetylase inhibitors sodium butyrate and trichostatin a on the energy metabolism of breast cancer cells. Int J Biochem Cell Biol 116:797-808. | LEAK ROUTINE OXPHOS ET | ROX | Intact cells | Human | Endothelial;epithelial;mesothelial cell Other cell lines |
Grimm 2015 Exp Gerontol | 2015 | Grimm C, Osiewacz HD (2015) Manganese rescues adverse effects on lifespan and development in Podospora anserina challenged by excess hydrogen peroxide. Exp Gerontol 63:8-17. | ROUTINE | CIV ROX | Isolated mitochondria Intact cells | Fungi | |
Hecker 2015 Methods Mol Biol | 2015 | Hecker M, Sommer N, Mayer K (2015) Assessment of short- and medium-chain fatty acids on mitochondrial function in severe Inflammation. Methods Mol Biol 1265:389-96. | LEAK ROUTINE ET | ROX | Intact cells | Human | Endothelial;epithelial;mesothelial cell |
Wuest 2015 J Physiol | 2015 | Wüst RC, Helmes M, Stienen GJ (2015) Rapid changes in NADH and flavin autofluorescence in rat cardiac trabeculae reveal large mitochondrial complex II reserve capacity. J Physiol 593:1829-40. | LEAK OXPHOS | N S NS ROX | Permeabilized tissue | Rat | Heart |
Bernhardt 2015 Sci Rep | 2015 | Bernhardt D, Müller M, Reichert AS, Osiewacz HD (2015) Simultaneous impairment of mitochondrial fission and fusion reduces mitophagy and shortens replicative lifespan. Sci Rep 5:7885. | ROUTINE ET | ROX | Intact cells | Saccharomyces cerevisiae | |
Ruiz-Perez 2015 J Biol Chem | 2015 | Ruiz-Pérez MV, Medina MÁ, Urdiales JL, Keinänen TA, Sánchez-Jiménez F (2015) Polyamine metabolism is sensitive to glycolysis inhibition in human neuroblastoma cells. J Biol Chem 290:6106-19. | LEAK ROUTINE ET | ROX | Intact cells | Human | Nervous system Other cell lines Neuroblastoma |
Torelli 2015 Free Radic Biol Med | 2015 | Torelli NQ, Ferreira-Júnior JR, Kowaltowski AJ, da Cunha FM (2015) RTG1- and RTG2-dependent retrograde signaling controls mitochondrial activity and stress resistance in Saccharomyces cerevisiae. Free Radic Biol Med 81C:30-7. | LEAK ROUTINE OXPHOS ET | CIV ROX | Isolated mitochondria Intact cells | Saccharomyces cerevisiae | |
Schoettl 2015 Endocrinology | 2015 | Schöttl T, Kappler L, Braun K, Fromme T, Klingenspor M (2015) Limited mitochondrial capacity of visceral versus subcutaneous white adipocytes in male C57BL/6N mice. Endocrinology 156:923-33. | LEAK ROUTINE OXPHOS ET | N S ROX | Permeabilized cells Isolated mitochondria Intact cells | Mouse | Fat |
Ziak 2015 Mitochondrion | 2015 | Ziak J, Krajcova A, Jiroutkova K, Nemcova V, Dzupa V, Duska F (2015) Assessing the function of mitochondria in cytosolic context in human skeletal muscle: Adopting high-resolution respirometry to homogenate of needle biopsy tissue samples. Mitochondrion 21:106-12. | LEAK OXPHOS ET | N S NS ROX | Homogenate Isolated mitochondria | Human | Skeletal muscle |
Hagl 2015 J Alzheimers Dis | 2015 | Hagl S, Grewal R, Ciobanu I, Helal A, Khayyal MT, Muller WE, Eckert GP (2015) Rice bran extract compensates mitochondrial dysfunction in a cellular model of early Alzheimer’s disease. J Alzheimers Dis 43:927-38. | LEAK OXPHOS ET | N S CIV NS ROX | Permeabilized cells | Rat | Nervous system Kidney Other cell lines |
Jeger 2015 BioMed Res Internat | 2015 | Jeger V, Brandt S, Porta F, Jakob SM, Takala J, Djafarzadeh S (2015) Dose response of Endotoxin on hepatocyte and muscle mitochondrial respiration in vitro. BioMed Res Internat Article ID 353074:1-13. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Isolated mitochondria Intact cells | Human | Skeletal muscle Liver Other cell lines |
Tan 2015 Cell Metab | 2015 | Tan AS, Baty JW, Dong L, Bezawork-Geleta A, Endaya B, Goodwin J, Bajzikova M, Kovarova J, Peterka M, Yan B, Pesdar EA, Sobol M, Filimonenko A, Stuart S, Vondrusova M, Kluckova K, Sachaphibulkij K, Rohlena J, Hozak P, Truksa J, Eccles D, Haupt LM, Griffiths LR, Neuzil J, Berridge MV (2015) Mitochondrial genome acquisition restores respiratory function and tumorigenic potential of cancer cells without mitochondrial DNA. Cell Metab 21:81-94. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Isolated mitochondria Intact cells | Human Mouse | Endothelial;epithelial;mesothelial cell Genital Other cell lines |
Seillier 2015 EMBO Mol Med | 2015 | Seillier M, Pouyet L, N'Guessan P, Nollet M, Capo F, Guillaumond F, Peyta L, Dumas JF, Varrault A, Bertrand G, Bonnafous S, Tran A, Meur G, Marchetti P, Ravier MA, Dalle S, Gual P, Muller D, Rutter GA, Servais S, Iovanna JL, Carrier A (2015) Defects in mitophagy promote redox-driven metabolic syndrome in the absence of TP53INP1. EMBO Mol Med 7:802-18. | LEAK ROUTINE OXPHOS ET | F CIV NS ROX | Permeabilized cells Intact cells | Human Mouse | Fibroblast |
Beauchamp 2015 Biosci Rep | 2015 | Beauchamp B, Thrush AB, Quizi J, Antoun G, McIntosh N, Al-Dirbashi OY, Patti ME, Harper ME (2015) Undernutrition during pregnancy in mice leads to dysfunctional cardiac muscle respiration in adult offspring. Biosci Rep 35. pii:e00200. | LEAK OXPHOS | F NS Other combinations ROX | Homogenate | Mouse | Heart Liver |
Garcia 2015 FASEB J | 2015 | García JA, Volt H, Venegas C, Doerrier C, Escames G, López LC, Acuña-Castroviejo D (2015) Disruption of the NF-κB/NLRP3 connection by melatonin requires retinoid-related orphan receptor-α and blocks the septic response in mice. FASEB J 29:3863-75. | OXPHOS | NS ROX | Permeabilized tissue | Mouse | Heart |
Chu 2015 Liver Transpl | 2015 | Chu MJ, Hickey AJ, Jiang Y, Petzer A, Bartlett AS, Phillips AR (2015) Mitochondrial dysfunction in steatotic rat livers occurs because a defect in complex I makes the liver susceptible to prolonged cold ischemia. Liver Transpl 21:396-407. | LEAK OXPHOS ET | N S ROX | Homogenate | Rat | Liver |
Kake-Guena 2015 J Exp Zool A Ecol Genet Physiol | 2015 | Kake-Guena SA, Touisse K, Vergilino R, Dufresne F, Blier PU, Lemieux H1 (2015) Assessment of mitochondrial functions in Daphnia pulex clones using high-resolution respirometry. J Exp Zool A Ecol Genet Physiol 323:292-300. | LEAK OXPHOS | N S CIV NS ROX | Permeabilized tissue | Crustaceans | |
Luevano-Martinez 2015 Biochim Biophys Acta | 2015 | Luévano-Martínez LA, Forni MF, Dos Santos VT, Souza-Pinto NC, Kowaltowski AJ (2015) Cardiolipin is a key determinant for mtDNA stability and segregation during mitochondrial stress. Biochim Biophys Acta 1847:587-98. | ROUTINE ET | ROX | Intact cells | Saccharomyces cerevisiae Fungi | |
Bonsignore 2015 Mech Ageing Dev | 2015 | Bonsignore LA, Tooley JG, Van Hoose PM, Wang E, Cheng A, Cole MP, Schaner Tooley CE (2015) NRMT1 knockout mice exhibit phenotypes associated with impaired DNA repair and premature aging. Mech Ageing Dev 146-148:42-52. | LEAK OXPHOS ET | N ROX | Isolated mitochondria | Mouse | Liver |
Makrecka-Kuka 2015 Biomolecules | 2015 | Makrecka-Kuka M, Krumschnabel G, Gnaiger E (2015) High-resolution respirometry for simultaneous measurement of oxygen and hydrogen peroxide fluxes in permeabilized cells, tissue homogenate and isolated mitochondria. https://doi.org/10.3390/biom5031319 | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Homogenate Isolated mitochondria Intact cells | Human Mouse | Heart Nervous system HEK |
Grabez 2015 J Anim Sci | 2015 | Grabež V, Kathri M, Phung V, Moe KM, Slinde E, Skaugen M, Saarem K, Egelandsdal B (2015) Protein expression and oxygen consumption rate of early postmortem mitochondria relate to meat tenderness. J Anim Sci 93:1967-79. | LEAK OXPHOS ET | F N S NS Other combinations ROX | Permeabilized tissue | Bovines | Skeletal muscle |
Ehinger 2015 J Neurol | 2015 | Ehinger JK, Morota S, Hansson MJ, Paul G, Elmér E (2015) Mitochondrial dysfunction in blood cells from amyotrophic lateral sclerosis patients. J Neurol 262:1493-503. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Intact cells | Human | Blood cells Lymphocyte Platelet |
Soares 2015 PLoS One | 2015 | Soares JB, Gaviraghi A, Oliveira MF (2015) Mitochondrial physiology in the major arbovirus vector Aedes aegypti: substrate preferences and sexual differences define respiratory capacity and superoxide production. PLoS One 10:e0120600. | LEAK OXPHOS ET | N S Gp NS Other combinations ROX | Permeabilized tissue Isolated mitochondria | Hexapods | Skeletal muscle |
Christiansen 2015 Am J Physiol Heart Circ Physiol | 2015 | Christiansen LB, Dela F, Koch J, Hansen CN, Leifsson PS, Yokota T (2015) Impaired cardiac mitochondrial oxidative phosphorylation and enhanced mitochondrial oxidative stress in feline hypertrophic cardiomyopathy. Am J Physiol Heart Circ Physiol 308:H1237-47. | LEAK OXPHOS ET | F N S CIV NS ROX | Permeabilized tissue Isolated mitochondria | Cat | Heart Skeletal muscle |
Melo Hanchuk 2015 Cell Signal | 2015 | Melo Hanchuk TD, Papa PF, La Guardia PG, Vercesi AE, Kobarg J (2015) Nek5 interacts with mitochondrial proteins and interferes negatively in mitochondrial mediated cell death and respiration. Cell Signal 27:1168-77. | LEAK OXPHOS | N S CIV ROX | Permeabilized cells | Human | HEK |
Venter 2015 J Clin Cell Immunol | 2015 | Venter G, Wijers M, Oerlemans FTJJ, Manjeri G, Fransen JAM, Wieringa B (2015) Glycolytic metabolism is differentially coupled to proliferative potential and morphodynamic capacity in RAW 264.7 and Mafb/C-Maf deficient macrophage lineages. J Clin Cell Immunol 6:1-11. | LEAK ROUTINE ET | ROX | Mouse | Blood cells Macrophage-derived | |
Teh 2015 Oncogene | 2015 | Teh JT, Zhu WL, Ilkayeva OR, Li Y, Gooding J, Casey PJ, Summers SA, Newgard CB, Wang M (2015) Isoprenylcysteine carboxylmethyltransferase regulates mitochondrial respiration and cancer cell metabolism. Oncogene 34:3296-304. | OXPHOS | N S DQ CIV ROX | Permeabilized cells | Human | Other cell lines |
Beier 2015 FASEB J | 2015 | Beier UH, Angelin A, Akimova T, Wang L, Liu Y, Xiao H, Koike MA, Hancock SA, Bhatti TR, Han R, Jiao J, Veasey SC, Sims CA, Baur JA, Wallace DC, Hancock WW (2015) Essential role of mitochondrial energy metabolism in Foxp3⁺ T-regulatory cell function and allograft survival. FASEB J 29:2315-26. https://doi.org/10.1096/fj.14-268409 | LEAK OXPHOS ET | N S NS ROX | Homogenate | Mouse | Nervous system |
Christiansen 2015 J Vet Med Sci | 2015 | Christiansen LB, Dela F, Koch J, Yokota T (2015) Tissue-specific and substrate-specific mitochondrial bioenergetics in feline cardiac and skeletal muscles. J Vet Med Sci 77:669-75. | LEAK OXPHOS ET | F N S CIV NS Other combinations ROX | Permeabilized tissue | Cat | Heart Skeletal muscle |
Iftikar 2015 Comp Biochem Physiol A Mol Integr Physiol | 2015 | Iftikar FI, Morash AJ, Cook DG, Herbert NA, Hickey AJ (2015) Temperature acclimation of mitochondria function from the hearts of a temperate wrasse (Notolabrus celidotus). Comp Biochem Physiol A Mol Integr Physiol 184:46-55. | LEAK OXPHOS ET | N S CIV NS ROX | Permeabilized tissue | Fishes | Heart |
Clemens 2015 Brain | 2015 | Clemens LE, Weber JJ, Wlodkowski TT, Yu-Taeger L, Michaud M, Calaminus C, Eckert SH, Gaca J, Weiss A, Magg JC, Jansson EK, Eckert GP, Pichler BJ, Bordet T, Pruss RM, Riess O, Nguyen HP (2015) Olesoxime suppresses calpain activation and mutant huntingtin fragmentation in the BACHD rat. Brain 138:3632-53. | LEAK OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Rat | Nervous system |
Petrus 2015 Can J Physiol Pharmacol | 2015 | Petruş A, Duicu OM, Sturza A, Noveanu L, Kiss L, Dănilă M, Baczkó I, Muntean DM, Jost N (2015) Modulation of mitochondrial respiratory function and ROS production by novel benzopyran analogues. Can J Physiol Pharmacol 93:811-8. | LEAK OXPHOS ET | N ROX | Isolated mitochondria | Rat | Heart |
Angebault 2015 Am J Hum Genet | 2015 | Angebault C, Guichet PO, Talmat-Amar Y, Charif M, Gerber S, Fares-Taie L, Gueguen N, Halloy F, Moore D, Amati-Bonneau P, Manes G, Hebrard M, Bocquet B, Quiles M, Piro-Mégy C, Teigell M, Delettre C, Rossel M, Meunier I, Preising M, Lorenz B, Carelli V, Chinnery PF, Yu-Wai-Man P, Kaplan J, Roubertie A, Barakat A, Bonneau D, Reynier P, Rozet JM, Bomont P, Hamel CP, Lenaers G (2015) Recessive mutations in RTN4IP1 cause isolated and syndromic optic neuropathies. Am J Hum Genet 97:754-60. | N S CIV NS ROX | Human | Endothelial;epithelial;mesothelial cell Fibroblast | ||
Czerniczyniec 2015 J Bioenerg Biomembr | 2015 | Czerniczyniec A, Lanza EM, Karadayian AG, Bustamante J, Lores-Arnaiz S (2015) Impairment of striatal mitochondrial function by acute paraquat poisoning. J Bioenerg Biomembr 47:395-408. | LEAK OXPHOS | N ROX | Isolated mitochondria | Rat | Nervous system |
Baris 2015 Am J Physiol Regul Integr Comp Physiol | 2015 | Baris TZ, Crawford DL, Oleksiak MF (2015) Acclimation and acute temperature effects on population differences in oxidative phosphorylation. Am J Physiol Regul Integr Comp Physiol 310:R185-96. | LEAK OXPHOS ET | N S CIV NS Other combinations ROX | Permeabilized tissue | Fishes | Heart |
Maiti 2015 PhD Thesis | 2015 | Maiti P (2015) The role of caseinolytic mitochondrial matrix peptidase proteolytic subunit (CLPP) in regulation of mitochondrial ribosome biogenesis in mammals. PhD Thesis 1-120. | LEAK OXPHOS ET | N S NS ROX | Isolated mitochondria | Mouse | Heart |
Victorino 2015 Tumour Biol | 2015 | Victorino VJ, Barroso WA, Assunção AK, Cury V, Jeremias IC, Petroni R, Chausse B, Ariga SK, Herrera AC, Panis C, Lima TM, Souza HP (2015) PGC-1β regulates HER2-overexpressing breast cancer cells proliferation by metabolic and redox pathways. Tumour Biol 37:6035-44. | LEAK ROUTINE ET | ROX | Intact cells | Human | Genital Other cell lines |
Hollis 2015 Proc Natl Acad Sci U S A | 2015 | Hollis F, van der Kooij MA, Zanoletti O, Lozano L, Cantó C, Sandi C (2015) Mitochondrial function in the brain links anxiety with social subordination. Proc Natl Acad Sci U S A 112:15486-91. | OXPHOS ET | N S NS ROX | Homogenate | Rat | Nervous system |
Lee 2015 Methods Mol Biol | 2015 | Lee W, Kelly RD, Yeung KY, Cagnone G, McKenzie M, John JC (2015) Analysis of mitochondrial DNA in induced pluripotent and embryonic stem cells. Methods Mol Biol 1330:219-52. | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Stem cells |
Rodrigues 2016 Biochem J | 2015 | Rodrigues MF, Obre E, Melo FH, Santos-Jr GC, Galina A, Jasiulionis MG, Rossignol R, Rumjanek FD, Amoedo ND (2016) Enhanced OXPHOS, glutaminolysis and beta-oxidation constitute the metastatic phenotype of melanoma cells. https://doi.org/10.1042/BJ20150645 | LEAK ROUTINE OXPHOS ET | F N S ROX | Permeabilized cells Intact cells | Mouse | Endothelial;epithelial;mesothelial cell Other cell lines |
Lages 2015 PeerJ | 2015 | Lages YM, Nascimento JM, Lemos GA, Galina A, Castilho LR, Rehen SK (2015) Low oxygen alters mitochondrial function and response to oxidative stress in human neural progenitor cells. PeerJ 3:e1486. | LEAK ROUTINE ET | ROX | Intact cells | Human | Stem cells |
Paeaesuke 2015 Oxid Med Cell Longev | 2015 | Pääsuke R, Eimre M, Piirsoo A, Peet N, Laada L, Kadaja L, Roosimaa M, Pääsuke M, Märtson A, Seppet E, Paju K (2015) Proliferation of human primary myoblasts is associated with altered energy metabolism in dependence of ageing in vivo and in vitro. Oxid Med Cell Longev 8296150:10p. | OXPHOS | N S CIV ROX | Permeabilized cells | Human | Skeletal muscle |
Harris 2015 Diabetes | 2015 | Harris LA, Skinner JR, Shew TM, Pietka TA, Abumrad NA, Wolins NE (2015) Perilipin 5-driven lipid droplet accumulation in skeletal muscle stimulates the expression of fibroblast growth factor 21. Diabetes 64:2757-68. | OXPHOS ET | N S NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
Patil 2015 J Nutr Biochem | 2015 | Patil YN, Dille KN, Burk DH, Cortez CC, Gettys TW (2015) Cellular and molecular remodeling of inguinal adipose tissue mitochondria by dietary methionine restriction. J Nutr Biochem 26:1235-47. | LEAK OXPHOS ET | F N S Gp ROX | Isolated mitochondria | Mouse | Skeletal muscle Liver Fat |
Errea 2015 J Neuroinflammation | 2015 | Errea O, Moreno B, Gonzalez-Franquesa A, Garcia-Roves PM, Villoslada P (2015) The disruption of mitochondrial axonal transport is an early event in neuroinflammation. J Neuroinflammation 12:152. | LEAK OXPHOS ET | N S CIV NS ROX | Homogenate | Mouse | Nervous system |
Sundaram 2015 Mol Microbiol | 2015 | Sundaram V, Petkova MI, Pujol-Carrion N, Boada J, de la Torre-Ruiz MA (2015) Tor1, Sch9 and PKA downregulation in quiescence rely on Mtl1 to preserve mitochondrial integrity and cell survival. Mol Microbiol 97:93-109. | LEAK ROUTINE ET | ROX | Intact cells | Saccharomyces cerevisiae | |
Kasvandik 2015 J Proteome Res | 2015 | Kasvandik S, Samuel K, Peters M, Eimre M, Peet N, Roost AM, Padrik L, Paju K, Peil L, Salumets A (2015) Deep quantitative proteomics reveals extensive metabolic reprogramming and cancer-like changes of ectopic endometriotic stromal cells. J Proteome Res 15:572-84. | LEAK ROUTINE ET | ROX | Human | Genital Other cell lines | |
Du 2015 J Biol Chem | 2015 | Du J, Rountree A, Cleghorn WM, Contreras L, Lindsay KJ, Sadilek M, Gu H, Djukovic D, Raftery D, Satrustegui J, Kanow M, Chan L, Tsang SH, Sweet IR, Hurley JB (2015) Phototransduction influences metabolic flux and nucleotide metabolism in mouse retina. J Biol Chem 291:4698-710. | LEAK ROUTINE OXPHOS ET | N ROX | Isolated mitochondria | Mouse | Nervous system Islet cell;pancreas;thymus |
Warne 2015 J Biol Chem | 2015 | Warne J, Pryce G, Hill JM, Shi X, Lennerås F, Puentes F, Kip M, Hilditch L, Walker P, Simone MI, Chan AWE, Towers GJ, Coker AR, Duchen MR, Szabadkai G, Baker D, Selwood DL (2015) Selective inhibition of the mitochondrial permeability transition pore protects against neuro-degeneration in experimental multiple sclerosis. J Biol Chem 291:4356-73. | LEAK OXPHOS ET | N ROX | Isolated mitochondria | Mouse | Liver |
Jiroutkova 2015 Crit Care | 2015 | Jiroutková K, Krajčová A, Ziak J, Fric M, Waldauf P, Džupa V, Gojda J, Němcova-Fürstová V, Kovář J, Elkalaf M, Trnka J, Duška F (2015) Mitochondrial function in skeletal muscle of patients with protracted critical illness and ICU-acquired weakness. Crit Care 19:448. | LEAK OXPHOS ET | N S Gp CIV NS Other combinations ROX | Homogenate | Human | Skeletal muscle |
Bock 2015 Thesis | 2015 | Bock UB (2015) Auswirkung von normobarer Hyperoxie auf die mitochondriale Atmung von Alveolarmakrophagen. Dissertation p80. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Intact cells | Mouse | Lung;gill Macrophage-derived |
Duicu 2015 Biomed Res Int | 2015 | Duicu OM, Lighezan R, Sturza A, Ceausu RA, Borza C, Vaduva A, Noveanu L, Gaspar M, Ionac A, Feier H, Muntean DM, Mornos C (2015) Monoamine oxidases as potential contributors to oxidative stress in diabetes: time for a study in patients undergoing heart surgery. Biomed Res Int 2015:515437. | LEAK OXPHOS ET | N S ROX | Permeabilized tissue | Human | Heart |
Fliri 2015 US Patent | 2015 | Fliri HG, Ford RL, Scowen DA, Batcheller DG, Ehinger J, Elmér E, Hansson MJ, Sjövall F (2015) Protected succinates for enhancing mitochondrial atp-production. US Patent US20150259317 A1. | ET | S NS ROX | Permeabilized cells Intact cells | Human | Blood cells Platelet |
Sjoevall 2015 US Patent | 2015 | Sjövall F, Ehinger J, Hansson M, Elmer E, Batcheller DG (2018) Mitochondrial toxicity test. US Patent US20150253306 A1. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Intact cells Permeabilized cells | Human | Blood cells Macrophage-derived Platelet |
Morato 2015 Cell Death Differ | 2015 | Morató L, Ruiz M, Boada J, Calingasan NY, Galino J, Guilera C, Jové M, Naudí A, Ferrer I, Pamplona R, Serrano M, Portero-Otín M, Beal MF, Fourcade S, Pujol A (2015) Activation of sirtuin 1 as therapy for the peroxisomal disease adrenoleukodystrophy. Cell Death Differ 22:1742-53. | LEAK OXPHOS | N S NS ROX | Permeabilized tissue | Mouse | Nervous system |
Guadalupe-Grau 2015 J Sports Sci | 2015 | Guadalupe-Grau A, Plenge U, Helbo S, Kristensen M, Andersen PR, Fago A, Belhage B, Dela F, Helge JW (2015) Effects of an 8-weeks erythropoietin treatment on mitochondrial and whole body fat oxidation capacity during exercise in healthy males. J Sports Sci 33:570-8. | LEAK OXPHOS | F N NS Other combinations ROX | Permeabilized tissue | Human | Skeletal muscle |
Hansen 2015 Shock | 2015 | Hansen ME, Simmons KJ, Tippetts TS, Thatcher MO, Saito RR, Hubbard ST, Trumbull AM, Parker BA, Taylor OJ, Bikman BT (2015) Lipopolysaccharide disrupts mitochondrial physiology in skeletal muscle via disparate effects on sphingolipid metabolism. Shock 44:585-92. | OXPHOS LEAK ET | N NS ROX | Permeabilized cells Permeabilized tissue | Mouse | Skeletal muscle Other cell lines |
Negmadjanov 2015 PLOS ONE | 2015 | Negmadjanov U, Godic Z, Rizvi F, Emelyanova L, Ross G, Richards J, Holmuhamedov EL, Jahangir A (2015) TGF-β1-mediated differentiation of fibroblasts is associated with increased mitochondrial content and cellular respiration. PLOS ONE 10:e0123046. doi: 10.1371/journal.pone.0123046. | LEAK ROUTINE ET | ROX | Mouse | Fibroblast | |
Farrar 2015 US Patent | 2015 | Farrar GJ, Millington-Ward S, Chadderton N (2015) Variants of yeast ndi1 gene, and uses thereof in the treatment of disease associated with mitochondrial dysfunction. US Patent WO 2013093029 A3. | ROUTINE | ROX | Human | HeLa | |
Boss 2015 US Patent | 2015 | Boss OD, Crisan M, Giacobino JP, (2015) Brown adipocyte progenitors in human sceletal muscle. US Patent US 2015/0240206 A1. | LEAK ROUTINE ET | ROX | Permeabilized cells | Human Mouse | Skeletal muscle Endothelial;epithelial;mesothelial cell Fat |
Hals 2015 PLoS One | 2015 | Hals IK, Bruerberg SG, Ma Z, Scholz H, Björklund A, Grill V (2015) Mitochondrial respiration in insulin-producing β-cells: general characteristics and adaptive effects of hypoxia. PLoS One 10:e0138558. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Rat | Islet cell;pancreas;thymus Other cell lines |
Assmann 2014 PhD Thesis | 2015 | Assmann N (2015) Impact of Fanconi-associated protein on the mitochonrial proteome. PhD Thesis 1-111. | LEAK ROUTINE OXPHOS ET | F N S CIV NS ROX | Permeabilized cells Intact cells | Pig | Kidney Other cell lines |
Siewiera 2015 Platelets | 2015 | Siewiera K, Kassassir H, Talar M, Wieteska L, Watala C (2015) Long-term untreated streptozotocin-diabetes leads to increased expression and elevated activity of prostaglandin H2 synthase in blood platelets. Platelets 27:203-11. | F ROX | Rat | Blood cells Platelet | ||
Cassina 2015 Biol Reprod | 2015 | Cassina AM, Silveira P, Cantu L, Montes JM, Radi R, Sapiro R (2015) Defective human sperm cells are associated with mitochondrial dysfunction and oxidant production. Biol Reprod 93:119. | LEAK ROUTINE ET | ROX | Human | Genital | |
Antoun 2015 JIMD Rep | 2015 | Antoun G, McBride S, Vanstone JR, Naas T, Michaud J, Redpath S, McMillan HJ, Brophy J, Daoud H, Chakraborty P, Dyment D, Holcik M, Harper ME, Lines MA (2015) Detailed biochemical and bioenergetic characterization of FBXL4-related encephalomyopathic mitochondrial DNA depletion. JIMD Rep 27:1-9. | LEAK OXPHOS ET | F N S CIV NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Kilbaugh 2015 J Am Heart Assoc | 2015 | Kilbaugh TJ, Sutton RM, Karlsson M, Hansson MJ, Naim MY, Morgan RW, Bratinov G, Lampe JW, Nadkarni VM, Becker LB, Margulies SS, Berg RA (2015) Persistently altered brain mitochondrial bioenergetics after apparently successful resuscitation from cardiac arrest. J Am Heart Assoc 4(9) pii: e002232. | LEAK OXPHOS ET | N S CIV NS ROX | Homogenate | Pig | Nervous system |
Hagl 2015 Molecules | 2015 | Hagl S, Berressem D, Bruns B, Sus N, Frank J, Eckert GP (2015) Beneficial Effects of Ethanolic and Hexanic Rice Bran Extract on Mitochondrial Function in PC12 Cells and the Search for Bioactive Components. Molecules 20(9):16524-39. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells | Rat | Nervous system Other cell lines |
Burtscher 2015 Mitochondrion | 2015 | Burtscher J, Zangrandi L, Schwarzer C, Gnaiger E (2015) Differences in mitochondrial function in homogenated samples from healthy and epileptic specific brain tissues revealed by high-resolution respirometry. Mitochondrion 25:104-12. | LEAK OXPHOS ET | N S CIV NS ROX | Permeabilized tissue Homogenate | Mouse | Nervous system |
Schirris 2015 Cell Metab | 2015 | Schirris TJ, Renkema GH, Ritschel T, Voermans NC, Bilos A, van Engelen BG, Brandt U, Koopman WJ, Beyrath JD, Rodenburg RJ, Willems PH, Smeitink JA, Russel FG (2015) Statin-induced myopathy is associated with mitochondrial complex III inhibition. Cell Metab 22:399-407. | ROUTINE OXPHOS ET | N S Gp CIV NS ROX | Permeabilized cells | Human Mouse | Skeletal muscle Other cell lines |
Gnaiger 2015 Scand J Med Sci Sports | 2015 | Gnaiger E, Boushel R, Søndergaard H, Munch-Andersen T, Damsgaard R, Hagen C, Díez-Sánchez C, Ara I, Wright-Paradis C, Schrauwen P, Hesselink M, Calbet JAL, Christiansen M, Helge JW, Saltin B (2015) Mitochondrial coupling and capacity of oxidative phosphorylation in skeletal muscle of Inuit and caucasians in the arctic winter. https://doi.org/10.1111/sms.12612 | LEAK OXPHOS ET | F N S ROX | Permeabilized tissue | Human | Skeletal muscle |
Lisak 2015 Cell Death Differ | 2015 | Lisak D, Schacht T, Gawlitza A, Albrecht P, Aktas O, Koop B, Gliem M, Hofstetter HH, Zanger K, Bultynck G, Parys JB, De Smedt H, Kindler T, Adams-Quack P, Hahn M, Waisman A, Reed JC, Hövelmeyer N, Methner A (2015) BAX inhibitor-1 is a Ca2+ channel critically important for immune cell function and survival. Cell Death Differ 23:358-68. | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Blood cells Lymphocyte |
Schoeckel 2015 Cancer Metab | 2015 | Schöckel L, Glasauer A, Basit F, Bitschar K, Truong H, Erdmann G, Algire C, Hägebarth A, Willems PH, Kopitz C, Koopman WJ, Héroult M (2015) Targeting mitochondrial complex I using BAY 87-2243 reduces melanoma tumor growth. Cancer Metab 3:11. | ROUTINE | ROX | Intact cells | Human Mouse | Endothelial;epithelial;mesothelial cell Other cell lines |
Lehtola 2015 Master's Thesis | 2015 | Lehtola A (2015) Main protein component of high density lipoprotein, apolipoprotein A1, modulates leukocyte cell respiration. Master's Thesis 1-44. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Intact cells Permeabilized cells | Human | Blood cells Other cell lines Lymphocyte |
Crombie 2015 Biochem Biophys Rep | 2015 | Crombie DE, van Bergena N, Davidsona KC, Anjomani Virmounib S, Mckelviec PA, Chrysostomoua V, Conquesta A, Corbend LA, Pookb MA, Kulkarnia T, Trouncea IA, Peraf MF, Delatyckid MB, Pébaya A (2015) Characterization of the retinal pigment epithelium in Friedreich ataxia. Biochem Biophys Rep 4:141–7. | LEAK OXPHOS ET | N S NS ROX | Permeabilized cells | Human | Nervous system Endothelial;epithelial;mesothelial cell Stem cells |
Chekulayev 2015 Biochem Biophys Rep | 2015 | Chekulayev V, Mado K, Shevchuk I, Koit A, Kaldma A, Klepinin A, Timohhina N, Tepp K, Kandashvili M, Ounpuu L, Heck K, Truu L, Planken A, Valvere V, Kaambre T (2015) Metabolic remodeling in human colorectal cancer and surrounding tissues: alterations in regulation of mitochondrial respiration and metabolic fluxes. Biochem Biophys Rep 4:111-25. | OXPHOS | N S CIV ROX | Permeabilized tissue | Human | Endothelial;epithelial;mesothelial cell |
Falabella 2015 Oxid Med Cell Longev | 2015 | Falabella M, Forte E, Magnifico MC, Santini P, Arese M, Giuffrè A, Radić K, Chessa L, Coarelli G, Buscarinu MC, Mechelli R, Salvetti M, Sarti P (2015) Evidence for detrimental cross interactions between reactive oxygen and nitrogen species in Leber’s hereditary optic neuropathy cells. Oxid Med Cell Longev 3187560. | ROUTINE | ROX | Intact cells | Human | Blood cells Lymphocyte |
Miwa 2015 Free Radic Biol Med | 2015 | Miwa S, Treumann A, Bell A, Vistoli G, Nelson G, Hay S, von Zglinicki T (2015) Carboxylesterase converts Amplex red to resorufin: Implications for mitochondrial H2O2 release assays. Free Radic Biol Med 90:173-83. | LEAK OXPHOS ET | N S ROX | Isolated mitochondria | Mouse | Liver |
Kruse 2015 Aging Cell | 2015 | Kruse SE, Karunadharma PP, Basisty N, Johnson R, Beyer RP, MacCoss MJ, Rabinovitch PS, Marcinek DJ (2015) Age modifies respiratory complex I and protein homeostasis in a muscle type-specific manner. Aging Cell 15:89-99. | LEAK OXPHOS ET | N S CIV NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
Six 2015 Cell Death Dis | 2015 | Six E, Lagresle-Peyrou C, Susini S, De Chappedelaine C, Sigrist N, Sadek H, Chouteau M, Cagnard N, Fontenay M, Hermine O, Chomienne C, Reynier P, Fischer A, André-Schmutz I, Gueguen N, Cavazzana M (2015) AK2 deficiency compromises the mitochondrial energy metabolism required for differentiation of human neutrophil and lymphoid lineages. Cell Death Dis 6:e1856. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells Other cell lines |
Schoerner 2014 Thesis University Giessen | 2014 | Schörner S (2014) Changes in function of mitochondrial respiratory chain in pulmonary artery smooth muscle cells under conditions of chronic hypoxia : measurements by respirometry and remission-spectrophotometry. Thesis University Giessen 130 pp. | LEAK ROUTINE ET | ROX | Rabbit | Endothelial;epithelial;mesothelial cell | |
Forkink 2014 Biochim Biophys Acta | 2014 | Forkink M, Manjeri GR, Liemburg-Apers DC, Nibbeling E, Blanchard M, Wojtala A, Smeitink JA, Wieckowski MR, Willems PH, Koopman WJ (2014) Mitochondrial hyperpolarization during chronic Complex I inhibition is sustained by low activity of Complex II, III, IV and V. Biochim Biophys Acta 1837:1247-56. | LEAK OXPHOS | N S CIV NS ROX | Permeabilized cells | Human | HEK |
Karabatsiakis 2014 Transl Psychiatry | 2014 | Karabatsiakis A, Boeck C, Salinas-Manrique J, Kolassa S, Calzia E, Dietrich DE, Kolassa IT (2014) Mitochondrial respiration in peripheral blood mononuclear cells correlates with depressive subsymptoms and severity of major depression. Transl Psychiatry 4:e397. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells |
Pham 2014 Am J Physiol | 2014 | Pham T, Loiselle D, Power A, Hickey AJ (2014) Mitochondrial inefficiencies and anoxic ATP hydrolysis capacities in diabetic rat heart. Am J Physiol 307:C499–507. | LEAK OXPHOS ET | N NS ROX | Homogenate | Rat | Heart |
Jelenik 2014 Diabetes | 2014 | Jelenik T, Séquaris G, Kaul K, Ouwens DM, Phielix E, Kotzka J, Knebel B, Weiß J, Reinbeck AL, Janke L, Nowotny P, Partke HJ, Zhang D, Shulman GI, Szendroedi J, Roden M (2014) Tissue-specific differences in the development of insulin resistance in a mouse model for type 1 diabetes. Diabetes 63:3856-67. | OXPHOS ET | N NS ROX | Permeabilized tissue Isolated mitochondria | Mouse | Skeletal muscle Liver |
Widmann 2014 Thesis | 2014 | Widmann M (2014) Effekte von Noradrenalin und LPS auf die mitochondriale Atmung von Alveolarmakrophagen. Thesis Universität Ulm, Medizinische Fakultät. 63 pp. | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Lung;gill Other cell lines |
Den Hollander 2014 Toxicol Sci | 2014 | den Hollander B, Sundström M, Pelander A, Ojanperä I, Mervaala E, Korpi ER, Kankuri E (2014) Keto amphetamine toxicity - focus on the redox reactivity of the cathinone designer drug mephedrone. Toxicol Sci 141:120-31. | LEAK OXPHOS ET | N S NS ROX | Homogenate | Mouse | Nervous system |
Krumschnabel 2014 Methods Enzymol | 2014 | Krumschnabel G, Eigentler A, Fasching M, Gnaiger E (2014) Use of safranin for the assessment of mitochondrial membrane potential by high-resolution respirometry and fluorometry. Methods Enzymol 542:163-81. https://doi.org/10.1016/B978-0-12-416618-9.00009-1 | LEAK OXPHOS ET | N S ROX | Homogenate | Mouse | Nervous system |
Afshordel 2014 Prostaglandins Leukot Essent Fatty Acids | 2014 | Afshordel S, Hagl S, Werner D, Roehner N, Koegel D, Bazan NG, Eckert GP (2014) Omega-3 polyunsaturated fatty acids improve mitochondrial dysfunction in brain aging - impact of Bcl-2 and NPD-1 like metabolites. Prostaglandins Leukot Essent Fatty Acids 92:23-31. | LEAK OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Mouse | Nervous system |
Damiano 2014 PLoS One | 2014 | Damiano M, Gautier CA, Bulteau AL, Ferrando-Miguel R, Gouarne C, Paoli MG, Pruss R, Auchère F, L'Hermitte-Stead C, Bouillaud F, Brice A, Corti O, Lombès A (2014) Tissue- and cell-specific mitochondrial defect in Parkin- deficient mice. PLoS One 9:e99898. | LEAK OXPHOS ET | N ROX | Isolated mitochondria | Mouse | Nervous system |
Iftikar 2014 Thesis University of Auckland | 2014 | Iftikar FI (2014) Testing the role of heart mitochondrial stability and function in heart failure of ectotherms exposed to heat stress. Thesis University of Auckland:167pp. | LEAK OXPHOS ET | N CIV NS ROX | Permeabilized tissue | Fishes | Heart |
Ryu 2014 Cell Metab | 2014 | Ryu D, Jo YS, Lo Sasso G, Stein S, Zhang H, Perino A, Lee JU, Zeviani M, Romand R, Hottiger MO, Schoonjans K, Auwerx J (2014) A SIRT7-dependent acetylation switch of GABPβ1 controls mitochondrial function. Cell Metab 20:856-69. | LEAK OXPHOS | N S CIV NS Other combinations ROX | Homogenate | Mouse | Heart Nervous system Liver Lung;gill |
Cedikova 2014 Evid Based Complement Alternat Med | 2014 | Cedikova M, Miklikova M, Stachova L, Grundmanova M, Tuma Z, Vetvicka V, Zech N, Kralickova M, Kuncova J (2014) Effects of the Czech propolis on sperm mitochondrial function. Evid Based Complement Alternat Med 248768. | LEAK OXPHOS ET | F N S CIV NS ROX | Permeabilized cells | Human | Genital |
Soltysinska 2014 PLoS One | 2014 | Soltysinska E, Bentzen BH, Barthmes M, Hattel H, Thrush AB, Harper ME, Qvortrup K, Larsen FJ, Schiffer TA, Losa-Reyna J, Straubinger J, Kniess A, Thomsen MB, Brüggemann A, Fenske S, Biel M, Ruth P, Wahl-Schott C, Boushel RC, Olesen SP, Lukowski R (2014) KCNMA1 encoded cardiac BK channels afford protection against ischemia-reperfusion injury. PLoS One 9:e103402. | LEAK OXPHOS | N NS ROX | Permeabilized tissue Isolated mitochondria | Mouse | Heart Skeletal muscle |
Slinde 2014 freepatentsonline.com | 2014 | Slinde E, Egelandsdal B (2014) Meat treatment and preservation method. Freepatentsonline.com 14/128207. | LEAK OXPHOS ET | F N NS ROX | Permeabilized tissue | Bovines | Skeletal muscle |
Khan 2014 J Comp Physiol | 2014 | Khan JR, Iftikar FI, Herbert NA, Gnaiger E, Hickey AJ (2014) Thermal plasticity of skeletal muscle mitochondrial activity and whole animal respiration in a common intertidal triplefin fish, Forsterygion lapillum (Family: Tripterygiidae). J Comp Physiol 184:991-1001. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Fishes | Skeletal muscle |
Chakraborty 2014 J Cardiovasc Dis | 2014 | Chakraborty M, Phillips ARJ, Macdonald J, Windsor JA, Hickey AJR (2014) Mitochondrial respiration in mononuclear cells and heart fibers in spontaneously hypertensive rats. J Cardiovasc Dis ISSN:2330-459. | LEAK ROUTINE OXPHOS ET | N S Gp CIV NS ROX | Permeabilized cells Permeabilized tissue | Rat | Heart Blood cells |
Koenemann 2014 Dissertation | 2014 | Koenemann B (2014) Einfluss der Hyperglykämie auf die mitochondriale Atmung von Leberzellen septischer Mäuse mit und ohne Imeglimin. PhD Thesis 1-61. | LEAK OXPHOS ET | F N S NS Other combinations ROX | Homogenate | Mouse | Liver |
Stokich 2014 Cryobiology | 2014 | Stokich B, Osgood Q, Grimm D, Moorthy S, Chakraborty N, Menze MA (2014) Cryopreservation of hepatocyte (HepG2) cell monolayers: Impact of trehalose. Cryobiology 69:281-90. | LEAK OXPHOS | N S NS ROX | Permeabilized cells | Human | Liver |
Gram 2014 Exp Gerontol | 2014 | Gram M, Vigelsoe A, Yokota T, Hansen CN, Helge JW, Hey-Mogensen M, Dela F (2014) Two weeks of one-leg immobilization decreases skeletal muscle 2 respiratory capacity equally in young and elderly men. Exp Gerontol 58C:269-78. | LEAK OXPHOS | N NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Davoudi 2014 PLoS One | 2014 | Davoudi M, Kotarsky H, Hansson E, Fellman V (2014) Complex I function and supercomplex formation are preserved in liver mitochondria despite progressive Complex III deficiency. PLoS One 9:e86767. | LEAK OXPHOS ET | N S ROX | Isolated mitochondria | Mouse | Liver |
Neves 2014 J Nutr Biochem | 2014 | Neves FA, Cortez E, Bernardoa AF, Mattos ABM, Vieira AK, Malafaia TO, Thole AA, Rodrigues-Cunha ACS, Garcia-Souza EP, Sichieri R, Moura AS (2014) Heart energy metabolism impairment in Western-diet induced obese mice. J Nutr Biochem 25:50-57. | LEAK OXPHOS | N NS ROX | Permeabilized tissue | Mouse | Heart |
Larsen 2014 Biochim Biophys Acta | 2014 | Larsen S, Díez-Sánchez C, Rabøl R, Royo IA, Dela F, Helge JW (2014) Increased intrinsic mitochondrial function in humans with mitochondrial haplogroup H. Biochim Biophys Acta 1837:226-31. | LEAK OXPHOS | N NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Boutant 2014 Mol Metab | 2014 | Boutant M, Joffraud M, Kulkarni SS, Garcia-Casarrubios E, Garcia-Roves PM, Ratajczak J, Fernandez-Marcos PJ, Valverde AM, Serrano M, Canto C (2014) SIRT1 enhances glucose tolerance by potentiating brown adipose tissue function. Mol Metab 4:118-31. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue Homogenate | Mouse | Skeletal muscle Liver Fat |
Logan 2014 Nat Genet | 2014 | Logan CV, Szabadkai G, Sharpe JA, Parry DA, Torelli S, Childs AM, Kriek M, Phadke R, Johnson CA, Roberts NY, Bonthron DT, Pysden KA, Whyte T, Munteanu I, Foley AR, Wheway G, Szymanska K, Natarajan S, Abdelhamed ZA, Morgan JE, Roper H, Santen GW, Niks EH, van der Pol WL, Lindhout D, Raffaello A, De Stefani D, den Dunnen JT, Sun Y, Ginjaar I, Sewry CA, Hurles M, Rizzuto R. UK10K Consortium, Duchen MR, Muntoni F, Sheridan E (2014) Loss-of-function mutations in MICU1 cause a brain and muscle disorder linked to primary alterations in mitochondrial calcium signaling. Nat Genet 46:188-93. | LEAK ROUTINE ET | ROX | Intact cells | Human | Fibroblast |
Mandò 2014 Am J Physiol Endocrinol Metab | 2014 | Mandò C, De Palma C, Stampalija T, Anelli GM, Figus M, Novielli C, Parisi F, Clementi E, Ferrazzi E, Cetin I (2014) Placental mitochondrial content and function in intrauterine growth restriction and preeclampsia. Am J Physiol Endocrinol Metab 306:E404-13. | ROUTINE OXPHOS | N S CIV NS ROX | Intact cells Permeabilized cells | Human | Genital |
Zambrano 2014 J Cell Biol | 2014 | Zambrano A, García-Carpizo V, Gallardo ME, Villamuera R, Gómez-Ferrería MA, Pascual A, Buisine N, Sachs LM, Garesse R, Aranda A (2014) The thyroid hormone receptor induces DNA damage and premature senescence. J Cell Biol 204:129-46. | LEAK OXPHOS ET | N ROX | Intact cells | Mouse | |
Hasenour 2014 J Biol Chem | 2014 | Hasenour CM, Ridley DE, Hughey CC, James FD, Donahue EP, Shearer J, Viollet B, Foretz M, Wasserman DH (2014) 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside (AICAR) effect on glucose production, but not energy metabolism, is independent of hepatic AMPK in vivo. J Biol Chem 289:5950-9. | LEAK OXPHOS ET | N ROX | Isolated mitochondria | Mouse | Liver |
Cordero-Reyes 2014 J Mol Cell Cardiol | 2014 | Cordero-Reyes AM, Gupte AA, Youker KA, Loebe M, Hsueh WA, Torre-Amione G, Taegtmeyer H, Hamilton DJ (2014) Freshly isolated mitochondria from failing human hearts exhibit preserved respiratory function. J Mol Cell Cardiol 68:98-105. | LEAK OXPHOS ET | N S ROX | Isolated mitochondria | Human | Heart |
Sonkar 2014 FASEB J | 2014 | Sonkar VK, Kulkarni PP, Dash D (2014) Amyloid beta peptide stimulates platelet activation through RhoA-dependent modulation of actomyosin organization. FASEB J 28:1819-29. | LEAK ROUTINE | ROX | Intact cells | Human Mouse | Blood cells Platelet |
Brandt 2014 Chem Biol Interact | 2014 | Brandt AP, do Rocio Andrade Pires A, Rocha ME, Noleto GR, Acco A, de Souza CE, Echevarria A, Dos Santos Canuto AV, Cadena SM (2014) Sydnone SYD-1 affects the metabolic functions of isolated rat hepatocytes. Chem Biol Interact 218C:107-14. | LEAK ROUTINE ET | ROX | Intact cells | Rat | Liver |
Miquel 2014 Free Radic Biol Med | 2014 | Miquel E, Cassina A, Martínez-Palma L, Souza JM, Bolatto C, Rodríguez-Bottero S, Logan A, Smith RA, Murphy MP, Barbeito L, Radi R, Cassina P (2014) Neuroprotective effects of the mitochondria-targeted antioxidant MitoQ in a model of inherited amyotrophic lateral sclerosis. Free Radic Biol Med 70:204-13. | LEAK OXPHOS ET | NS ROX | Permeabilized tissue | Mouse | Skeletal muscle Nervous system |
Schmidl 2014 Blood | 2014 | Schmidl C, Renner K, Peter K, Eder R, Lassmann T, Balwierz PJ, Itoh M, Nagao-Sato S, Kawaji H, Carninci P, Suzuki H, Hayashizaki Y, Andreesen R, Hume DA, Hoffmann P, Forrest AR, Kreutz MP, Edinger M, Rehli M (2014) Transcription and enhancer profiling in human monocyte subsets. Blood 123:e90-9. | ROUTINE | CIV ROX | Permeabilized cells Intact cells | Human | Blood cells |
Kukat 2014 PLoS Genet | 2014 | Kukat A, Dogan SA, Edgar D, Mourier A, Jacoby C, Maiti P, Mauer J, Becker C, Senft K, Wibom R, Kudin AP, Hultenby K, Flögel U, Rosenkranz S, Ricquier D, Kunz WS, Trifunovic A (2014) Loss of UCP2 attenuates mitochondrial dysfunction without altering ROS production and uncoupling activity. https://doi.org/10.1371/journal.pgen.1004385 | LEAK OXPHOS ET | F N S NS ROX | Isolated mitochondria | Mouse | Heart |
Doridot 2014 Antioxid Redox Signal | 2014 | Doridot LD Chatre LD, Ducat A, Vilotte JL, Lombes A, Méhats C, Barbaux S, Calicchio R, Ricchetti M, Vaiman D (2014) Nitroso-redox balance and mitochondrial homeostasis are regulated by STOX1, a pre-eclampsia associated gene. Antioxid Redox Signal 21:819-34. | LEAK ROUTINE ET | ROX | Human | Endothelial;epithelial;mesothelial cell Other cell lines | |
Sjoevall 2014 PLoS One | 2014 | Sjövall F, Morota S, Asander Frostner E, Hansson Magnus J, Elmer E (2014) Cytokine and nitric oxide levels in patients with sepsis - temporal evolvement and relation to platelet mitochondrial respiratory function. PLoS One 9:e97673. | LEAK OXPHOS ET | N S CIV NS ROX | Permeabilized cells | Human | Blood cells Platelet |
Garratt 2014 Proc Natl Acad Sci U S A | 2014 | Garratt M, Pichaud N, Glaros EN, Kee AJ, Brooks RC (2014) Superoxide dismutase deficiency impairs olfactory sexual signaling and alters bioenergetic function in mice. Proc Natl Acad Sci U S A 111:8119-24. | LEAK OXPHOS ET | F N S CIV NS ROX | Permeabilized tissue | Mouse | Liver |
Piel 2014 Acta Physiol (Oxf) | 2014 | Piel S, Ehinger JK, Elmér E, Hansson Magnus J (2014) Metformin induces lactate production in peripheral blood mononuclear cells and platelets through specific mitochondrial Complex I inhibition. Acta Physiol (Oxf) 213:171-80. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Intact cells | Human | Blood cells Other cell lines Platelet |
Cavalcanti-de-Albuquerque 2014 J Appl Physiol | 2014 | Cavalcanti-de-Albuquerque JP, Salvador IC, Martins EL, Jardim-Messeder D, Werneck-de-Castro JP, Galina A, Carvalho DP (2014) Role of estrogen on skeletal muscle mitochondrial function in ovariectomized rats: a time course study in different fiber types. J Appl Physiol 116:779-89. | LEAK OXPHOS | F N Gp NS ROX | Permeabilized tissue | Rat | Skeletal muscle |
Fisar 2014 Toxicol Lett | 2014 | Fišar Z, Singh N, Hroudová J (2014) Cannabinoid-induced changes in respiration of brain mitochondria. Toxicol Lett 231:62-71. | LEAK OXPHOS ET | N S CIV ROX | Isolated mitochondria | Pig | Nervous system |
Gnaiger 2014 MitoPathways | 2014 |
Gnaiger E (2014) Mitochondrial pathways and respiratory control. An introduction to OXPHOS analysis. 4th ed. Mitochondr Physiol Network 19.12. Oroboros MiPNet Publications, Innsbruck:80 pp. — see 5th edition: Gnaiger 2020 BEC MitoPathways. | LEAK ROUTINE OXPHOS ET | F N S Gp CIV NS ROX | Permeabilized cells Permeabilized tissue Homogenate Isolated mitochondria Intact cells | Human Mouse | Heart Skeletal muscle Fibroblast |
Divakaruni 2014 Curr Protoc Toxicol | 2014 | Divakaruni AS, Rogers GW, Murphy AN (2014) Measuring mitochondrial function in permeabilized cells using the Seahorse XF Analyzer or a clark-type oxygen electrode. Curr Protoc Toxicol 60:25.2.1-25.2.16. | LEAK OXPHOS ET | F N S Gp CIV ROX | Permeabilized cells | Mouse | Skeletal muscle Other cell lines |
Felser 2014 Toxicology II | 2014 | Felser A, Lindinger PW, Schnell D, Kratschmar DV, Odermatt A, Mies S, Jenö P, Krähenbühl S (2014) Hepatocellular toxicity of benzbromarone: effects on mitochondrial function and structure. Toxicology 324:136-46. | LEAK ROUTINE OXPHOS ET | N S ROX | Intact cells | Human | Liver Other cell lines |
Kaldma 2014 Int J Biochem Cell Biol | 2014 | Kaldma A, Klepinin A, Chekulayev V, Mado K, Shevchuk I, Timohhina N, Tepp K, Kandashvili M, Varikmaa M, Koit A, Planken M, Heck K, Truu L, Planken A, Valvere V, Rebane E, Kaambre T (2014) An in situ study of bioenergetic properties of human colorectal cancer: The regulation of mitochondrial respiration and distribution of flux control among the components of ATP synthasome. Int J Biochem Cell Biol 55C:171-86. | LEAK OXPHOS | N S CIV NS ROX | Permeabilized tissue | Human | Genital |
Pulliam 2014 Biochem J | 2014 | Pulliam DA, Deepa SS, Liu Y, Hill S, Lin AL, Bhattacharya A, Shi Y, Sloane L, Viscomi C, Zeviani M, Van Remmen H (2014) Complex IV-deficient Surf1(-/-) mice initiate mitochondrial stress responses. Biochem J 462:359-71. | LEAK OXPHOS | N ROX | Isolated mitochondria | Mouse | Heart Skeletal muscle |
Glaser 2014 Thesis | 2014 | Glaser V (2014) Efeitos da hiperglicemia cronica e seus metabolitos, metilglioxal e produtos terminais de glicacao, na fisiologia e dinamica mitochondrial no sistema nervoso central. PhD Thesis 1-117. | LEAK ROUTINE ET | ROX | Intact cells | Rat | Nervous system Other cell lines |
Hunter 2014 PhD Thesis | 2014 | Hunter FW (2014) Old target; new paradigm: Determinants of sensitivity to hypoxia-directed anticancer prodrugs. PhD Thesis:1-353. | S ROX | Intact cells | Other mammals | CHO | |
Shama 2014 Funct Ecol | 2014 | Shama LNS, Strobel A, Mark FC, Wegner KM (2014) Transgenerational plasticity in marine sticklebacks: maternal effects mediate impacts of a warming ocean. Funct Ecol 28:1482–93. | LEAK OXPHOS ET | N ROX | Permeabilized tissue | Fishes | Heart |
Broeker 2014 Thesis | 2014 | Broeker C (2014) Mitochondriopathien als Ursache des renalen Fanconi-Syndroms. Dissertation 85pp. | LEAK OXPHOS ET | N CIV NS ROX | Permeabilized cells | Pig | Kidney Other cell lines |
Valenti 2014 Anal Biochem | 2014 | Valenti D, de Bari L, De Filippis B, Ricceri L, Vacca RA (2014) Preservation of mitochondrial functional integrity in mitochondria isolated from small cryopreserved mouse brain areas. Anal Biochem 444:25-31. | OXPHOS ET | N S ROX | Isolated mitochondria | Mouse | Nervous system |
Frederick 2014 J Biol Chem | 2014 | Frederick DW, Davis JG, Dávila A Jr, Agarwal B, Michan S, Puchowicz MA, Nakamaru-Ogiso E, Baur JA (2014) Increasing NAD synthesis in muscle via nicotinamide phosphoribosyltransferase is not sufficient to promote oxidative metabolism.. J Biol Chem. 290:1546-58. | LEAK OXPHOS | F N S ROX | Isolated mitochondria | Mouse | Skeletal muscle |
Hagl 2014 J Alzheimers Dis b | 2014 | Hagl S, Heinrich M, Kocher A, Schiborr C, Frank J, Eckert GP (2014) Curcumin micelles improve mitochondrial function in a mouse model of Alzheimer’s disease. J Alzheimers Dis 1:80-3. | LEAK OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Mouse | Nervous system |
Tippets 2014 BMC Cardiovasc Disord | 2014 | Tippetts TS, Winden DR, Swensen AC, Nelson MB, Thatcher MO, Saito RR, Condie TB, Simmons KJ, Judd AM, Reynolds PR, Bikman BT (2014) Cigarette smoke increases cardiomyocyte ceramide accumulation and inhibits mitochondrial respiration. BMC Cardiovasc Disord 14:165. | LEAK OXPHOS ET | N S NS ROX | Permeabilized cells Permeabilized tissue Isolated mitochondria | Mouse Rat | Heart Other cell lines |
Iglesias-Gonzalez 2014 PhD Thesis | 2014 | Iglesias-Gonzalez J (2014) Neurotoxicity induced by oxidative stress and aluminium in relation to Parkinson’s disease: a mitochondrial bioenergetic approach by high-resolution respirometry. PhD Thesis 1-242. | LEAK OXPHOS ET | N S NS ROX | Isolated mitochondria | Rat | Nervous system |
Thatcher 2014 Am J Physiol Endocrinol Metab | 2014 | Thatcher MO, Tippetts TS, Nelson MB, Swensen AC, Winden DR, Hansen ME, Anderson MC, Johnson IE, Porter JP, Reynolds PR, Bikman BT (2014) Ceramides mediate cigarette smoke-induced metabolic disruption in mice. Am J Physiol Endocrinol Metab 307:E919-27. | LEAK OXPHOS ET | N S NS ROX | Permeabilized cells Permeabilized tissue | Human Mouse | Skeletal muscle |
Pecina 2014 Biochim Biophys Acta Clinical | 2014 | Pecina P, Houstkova H, Mracek T, Pecinova A, Nuskova H.Tesarova M, Hansikova H, Janota J, Zemanc J, Houstek J (2014) Noninvasive diagnostics of mitochondrial disorders in isolated lymphocytes with high resolution respirometry. Biochim Biophys Acta Clinical 2:62–71. | LEAK OXPHOS | N Gp CIV Other combinations ROX | Permeabilized cells | Human | Blood cells Lymphocyte |
Serteyn 2014 Bioenergetics | 2014 | Serteyn D, de la Rebière de Pouyade G, Sandersen C, Salciccia A, Grulke S, Mouithys-Mickalad A, Franck T, Lejeune JP, Ceusters Justine D (2014) Muscle mitochondrial dysfunction in horses affected by acute laminitis. Bioenergetics 3:1-7. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Horse | Skeletal muscle |
Bleier 2014 Free Radic Biol Med | 2014 | Bleier L, Wittig I, Heide H, Steger M, Brandt U, Droese S4 (2014) Generator-specific targets of mitochondrial reactive oxygen species. Free Radic Biol Med 78:1-10. | OXPHOS | N S ROX | Isolated mitochondria | Rat | Heart |
Rudnicki 2014 United States Patent Application Publication | 2014 | Rudnicki MA, Yin Hang (2014) MICRORNA INHIBITORS. United States Patent Application Publication 1-49. | LEAK ROUTINE OXPHOS ET | F N S NS ROX | Permeabilized cells Intact cells | Mouse | Skeletal muscle Fat |
Holm 2013 PLoS One | 2013 | Holm T, Brøgger-Jensen MR, Johnson L, Kessel L (2013) Glutathione preservation during storage of rat lenses in optisol-GS and castor oil. PLoS One 8:e79620. | LEAK OXPHOS | NS ROX | Homogenate | Rat | Endothelial;epithelial;mesothelial cell |
Smith 2013 Biochem J | 2013 | Smith ME, Tippetts TS, Brassfield ES, Tucker BJ, Ockey A, Swensen AC, Anthonymuthu TS, Washburn TD, Kane DA, Prince JT, Bikman BT (2013) Mitochondrial fission mediates ceramide-induced metabolic disruption in skeletal muscle. Biochem J 456:427-39. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized tissue Intact cells | Mouse | Skeletal muscle Other cell lines |
Reilly 2013 J Exp Biol | 2013 | Reilly BD, Hickey AJ, Cramp RL, Franklin CE (2013) Decreased hydrogen peroxide production and mitochondrial respiration in skeletal muscle but not cardiac muscle of the green-striped burrowing frog, a natural model of muscle disuse. J Exp Biol 217:1087-93. | LEAK OXPHOS | NS ROX | Permeabilized tissue | Amphibians | Heart Skeletal muscle |
Sjövall 2013 Thesis Lund University - Sweden | 2013 | Sjövall F (2013) Mitochondrial function in sepsis - temporal evolvement of respiratory capacity in human blood cells. Thesis Lund University - Sweden 83pp. | LEAK ROUTINE OXPHOS ET | N S ROX | Intact cells Permeabilized cells | Human | Blood cells Platelet |
Lanza 2013 Am J Physiol Endocrinol Metab | 2013 | Lanza IR, Blachnio-Zabielska A, Johnson ML, Schimke JM, Jakaitis DR, Lebrasseur NK, Jensen MD, Sreekumaran Nair K, Zabielski P (2013) Influence of fish oil on skeletal muscle mitochondrial energetics and lipid metabolites during high-fat diet. Am J Physiol Endocrinol Metab 304:E1391-403. | LEAK OXPHOS | F N S NS ROX | Isolated mitochondria | Mouse | Skeletal muscle |
Dickinson 2013 Thesis University of Warwick - Great Britain | 2013 | Dickinson A (2013) The role of mitochondrial DNA in tumorigenesis. Thesis University of Warwick - Great Britain 292pp. | LEAK ROUTINE ET | ROX | Intact cells | Human | Other cell lines |
Takahashi 2013 Mech Ageing Dev | 2013 | Takahashi K, Takahashi M (2013) Exogenous administration of coenzyme Q10 restores mitochondrial 3 oxygen consumption in the aged mouse brain. Mech Ageing Dev 134:580-6. | OXPHOS | N NS ROX | Isolated mitochondria | Mouse | Nervous system |
Henriques 2013 Thesis Universidade de Coimbra - Portugal | 2013 | Henriques TAF (2013) High-resolution respirometry for metabolic profiling of acute rat hippocampal slices. Thesis Universidade de Coimbra - Portugal 38pp. | LEAK ROUTINE ET | N S ROX | Intact cells | Rat | Nervous system |
Casanova 2013 Thesis Universitat Rovira i Virgili - Spain | 2013 | Casanova Vallvé E (2013) Modulation of Mmuscle energy metabolism by bioactive compounds. Thesis Universitat Rovira i Virgili - Spain 117pp. | ROUTINE ET | N S NS ROX | Intact cells | Rat | Skeletal muscle |
Pichaud 2013 J Bioenerg Biomembr | 2013 | Pichaud N, Ballard JWO, Tanguay RM, Blier PU (2013) Mitochondrial haplotype divergences affect specific temperature sensitivity of mitochondrial respiration. J Bioenerg Biomembr 45:25-35. | LEAK OXPHOS ET | N NS ROX | Permeabilized tissue | Hexapods | Skeletal muscle |
Alvarez-Fischer 2013 J Neurochem | 2013 | Alvarez-Fischer D, Noelker C, Grünewald A, Vulinović F, Guerreiro S, Fuchs J, Lu L, Lombès A, Hirsch EC, Oertel WH, Michel PP, Hartmann A (2013) Probenecid potentiates MPTP/MPP+ toxicity by interference with cellular energy metabolism. J Neurochem 127:782-92. | LEAK OXPHOS | N ROX | Mouse | ||
Gupte 2013 Endocrinology | 2013 | Gupte AA, Minze LJ, Reyes M, Ren Y, Wang X, Brunner G, Ghosn M, Cordero-Reyes AM, Ding K, Pratico D, Morrisett J, Shi ZZ, Hamilton DJ, Lyon CJ, Hsueh WA (2013) High fat feeding-induced hyperinsulinemia increases cardiac glucose uptake and mitochondrial function despite peripheral insulin resistance. Endocrinology 154:2650-62. | LEAK OXPHOS ET | N S ROX | Isolated mitochondria | Mouse | Heart |
Munro 2013 Aging Cell | 2013 | Munro D, Pichaud N, Paquin F, Kemeid V, Blier PU (2013) Low hydrogen peroxide production in mitochondria of the long-lived Arctica islandica: underlying mechanisms for slow aging. Aging Cell 12:5845-92. | LEAK OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Molluscs | Endothelial;epithelial;mesothelial cell |
Zeh 2013 Thesis | 2013 | Zeh RM (2013) Neurological and molecular biological characterisation of the mutant mouse line Tom40. Thesis Technische Universität München 243pp. | OXPHOS ET | N S ROX | Isolated mitochondria | Rat | Heart Nervous system |
Hall 2013 Oncotarget | 2013 | Hall A, Meyle KD, Lange MK, Klima M, Sanderhoff M, Dahl C, Abildgaard C, Thorup K, Moghimi SM, Jensen PB, Bartek J, Guldberg P, Christensen C (2013) Dysfunctional oxidative phosphorylation makes malignant melanoma cells addicted to glycolysis driven by the (V600E)BRAF oncogene. Oncotarget 4:584-99. | LEAK OXPHOS ET | N ROX | Human | Other cell lines | |
Hals 2013 J Diabetes Res | 2013 | Hals IK, Rokstad AM, Strand BL, Oberholzer J, Grill V (2013) Alginate microencapsulation of human islets does not increase susceptibility to acute hypoxia. J Diabetes Res 2013:374925. | ROUTINE ET | N ROX | Intact cells | Human | Islet cell;pancreas;thymus |
Pichaud 2013 J Exp Biol | 2013 | Pichaud N, Garratt M, Ballard JWO, Brooks RC (2013) Physiological adaptations to reproduction II. Mitochondrial adjustments in livers of lactating mice. J Exp Biol 216:2889-95. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Mouse | Liver |
Jacobs 2013 J Appl Physiol | 2013 | Jacobs R, Flück D, Bonne TC, Bürgi S, Christensen PM, Toigo M, Lundby C (2013) Improvements in exercise performance 1 with high-intensity interval training 2 coincide with an increase in skeletal muscle mitochondrial content and function. J Appl Physiol 115:785-93. | LEAK OXPHOS ET | F N S CIV NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Smith 2013 Thesis The University of Guelph - Canada | 2013 | Smith BK (2013) Investigations into the regulation of skeletal muscle mitochondrial metabolism. Thesis The University of Guelph - Canada 139pp. | LEAK OXPHOS ET | N NS ROX | Permeabilized tissue | Rat | Skeletal muscle |
Stephenson 2013 Thesis Royal Melbourne Institute of Technology - Melbourne | 2013 | Stephenson EJ (2013) Mitochondrial function in metabolic health. Thesis Royal Melbourne Institute of Technology - Melbourne: 106pp. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Rat | Skeletal muscle |
Rojahn 2013 Thesis Norwegian University of Life Sciences - Ås | 2013 | Rojahn L (2013) Effects of micronutrients on survival and mitochondrial viability in honey bees (Apis mellifera). Thesis Norwegian University of Life Sciences - Ås: 41 pp. | OXPHOS ET | N S ROX | Permeabilized tissue | Hexapods | Skeletal muscle |
Fetterman 2013 Biochem J | 2013 | Fetterman JL, Zelickson BR, Johnson LW, Moellering DR, Westbrook DG, Pompilius M, Sammy MJ, Johnson M, Dunham-Snary KJ, Cao X, Bradley WE, Zhang J, Wei CC, Chacko B, Schurr TG, Kesterson RA, Dell'italia LJ, Darley-Usmar VM, Welch DR, Ballinger SW (2013) Mitochondrial genetic background modulates bioenergetics and susceptibility to acute cardiac volume overload. Biochem J 455:157-67. | LEAK OXPHOS | N ROX | Isolated mitochondria | Mouse | Heart |
Dickinson 2013 Cell Death Differ | 2013 | Dickinson A, Yeung KY, Donoghue J, Baker MJ, Kelly RDW, McKenzie M, Johns TG, St. John JC (2013) The regulation of mitochondrial DNA copy number in glioblastoma cells. Cell Death Differ 20:1644–53. | LEAK ROUTINE ET | ROX | Human | Nervous system Other cell lines | |
Jacobs 2013 J Gerontol A Biol Sci Med Sci | 2013 | Jacobs R, Diaz V, Soldini L, Haider T, Thomassen M, Nordsborg NB, Gassmann M, Lundby C (2013) Fast-twitch glycolytic skeletal muscle is predisposed to age-induced impairments in mitochondrial function. J Gerontol A Biol Sci Med Sci 68:1010-22. | LEAK OXPHOS ET | F N S NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
Cahill 2013 Biofouling | 2013 | Cahill PL, Heasman K, Hickey A, Mountfort D, Jeffs A, Kuhajek J (2013) Screening for negative effects of candidate ascidian antifoulant compounds on a target aquaculture species, Perna canaliculus Gmelin. Biofouling 29:29-37. | LEAK OXPHOS ET | N S ROX | Permeabilized tissue | Molluscs | Lung;gill |
Strobel 2013 PLoS One | 2013 | Strobel A, Graeve M, Poertner HO, Mark FC (2013) Mitochondrial acclimation capacities to ocean warming and acidification are limited in the antarctic nototheniid fish, Notothenia rossii and Lepidonotothen squamifrons. PLoS One 8:e68865. | LEAK OXPHOS ET | N S NS ROX | Isolated mitochondria | Fishes | Liver |
Mayeur 2013 PhD Thesis | 2013 | Mayeur S (2013) Retard de croissance intra-utérin et vulnérabilité au syndrome métabolique: recherche de marqueurs placentaires dans un modèle de dénutrition maternelle prénatale et chez l'Homme. PhD Thesis 1-225. | LEAK OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Rat | Genital |
Sjoevall 2013 Crit Care | 2013 | Sjoevall F, Morota S, Persson J, Hansson Magnus J, Elmer E (2013) Patients with sepsis exhibit increased mitochondrial respiratory capacity in peripheral blood immune cells. Crit Care 17:R152. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Intact cells | Human | Blood cells |
Chu 2013 PLoS One | 2013 | Chu MJ, Phillips AR, Hosking AW, Macdonald JR, Bartlett AS, Hickey AJ (2013) Hepatic mitochondrial function analysis using needle liver biopsy samples. PLoS One 8:e79097. | LEAK OXPHOS ET | N ROX | Permeabilized tissue | Human Rat | Liver |
Schwarzkopf 2013 Pharmazie | 2013 | Schwarzkopf TM, Hagl S, Eckert GP, Klein J (2013) Neuroprotection by bilobalide in ischemia: improvement of mitochondrial function. Pharmazie 68:584-9. | LEAK OXPHOS ET | N S CIV ROX | Isolated mitochondria | Mouse | Nervous system |
Hernandez-Alvarez 2013 Antioxid Redox Signal | 2013 | Hernández-Alvarez MI, Paz JC, Sebastián D, Muñoz JP, Liesa M, Segalés J, Palacín M, Zorzano A (2013) Glucocorticoid modulation of mitochondrial function in hepatoma cells requires the mitochondrial fission protein Drp1. Antioxid Redox Signal 19:366-78. | OXPHOS ET | N S NS ROX | Homogenate | Rat | Liver Other cell lines |
Schneeberger 2013 Cell | 2013 | Schneeberger M, Dietrich MO, Sebastián D, Imbernón M, Castaño C, Garcia A, Esteban Y, Gonzalez-Franquesa A, Rodríguez IC, Bortolozzi A, Garcia-Roves PM, Gomis R, Nogueiras R, Horvath TL, Zorzano A, Claret M (2013) Mitofusin 2 in POMC neurons connects ER stress with leptin resistance and energy imbalance. Cell 155:172-87. | LEAK OXPHOS ET | N NS ROX | Homogenate | Mouse | Nervous system |
Perales Villarroel 2013 J Surg Res | 2013 | Perales Villarroel JP, Figueredo R, Guan Y, Tomaiuolo M, Karamercan MA, Welsh J, Selak MA, Becker LB, Sims C (2013) Increased platelet storage time is associated with mitochondrial dysfunction and impaired platelet function. J Surg Res 184:422-9. | ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells | Human | Blood cells Platelet |
Monteiro 2013 Thesis | 2013 | Monteiro Siqueira C (2013) Avaliação de medicamentos homeopáticos para gripe humana por ensaios in vitro, pré-clínico e clínico. Dissertation p152. | LEAK ROUTINE ET | CIV ROX | Intact cells | Dog | Kidney Other cell lines |
Hagl 2013 Pharmacol Res | 2013 | Hagl S, Kocher A, Schiborr C, Eckert SH, Ciobanu I, Birringer M, El-Askary H, Helal A, Khayyal MT, Frank J, Muller WE, Eckert GP (2013) Rice bran extract protects from mitochondrial dysfunction in guinea pig brains. Pharmacol Res 76C:17-27. | LEAK OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Guinea pig | Nervous system |
Aidt 2013 PLoS Curr | 2013 | Aidt FH, Nielsen SM, Kanters J, Pesta D, Nielsen TT, Nørremølle A, Hasholt L, Christiansen M, Hagen CM (2013) Dysfunctional mitochondrial respiration in the striatum of the Huntington's disease transgenic R6/2 mouse model. PLoS Curr 5. pii:ecurrents.hd.d8917b4862929772c5a2f2a34ef1c201. | LEAK OXPHOS ET | N S CIV NS ROX | Homogenate | Mouse | Nervous system |
Hall 2013 Biochim Biophys Acta | 2013 | Hall A, Larsen AK, Parhamifar L, Meyle KD, Wu LP, Moghimi SM (2013) High-resolution respirometry analysis of polyethylenimine-mediated mitochondrial energy crisis and cellular stress: Mitochondrial proton leak and inhibition of the electron transport system. Biochim Biophys Acta 1827:1213-25. | LEAK ROUTINE OXPHOS ET | N S CIV ROX | Isolated mitochondria SMP | Mouse | Liver Other cell lines |
Sjoevall 2013 Mitochondrion | 2013 | Sjövall F, Ehinger JK, Marelsson SE, Morota S, Asander Frostner E, Uchino H, Lundgren J, Arnbjörnsson E, Hansson Magnus J, Fellman V, Elmér E (2013) Mitochondrial respiration in human viable platelets - methodology and influence of gender, age and storage. Mitochondrion 13:7-14. | LEAK ROUTINE OXPHOS ET | N ROX | Permeabilized cells Intact cells | Human | Blood cells Platelet |
Iftikar 2013 PLoS One | 2013 | Iftikar FI, Hickey AJ (2013) Do mitochondria limit hot fish hearts? Understanding the role of mitochondrial function with heat stress in Notolabrus celidotus. PLoS One 8:e64120. | LEAK OXPHOS ET | N CIV NS ROX | Permeabilized tissue | Fishes | Heart |
Weidinger 2013 Front Physiol | 2013 | Weidinger A, Dungel P, Perlinger M, Singer K, Ghebes C, Duvigneau JC, Müllebner A, Schäfer U, Redl H, Kozlov AV (2013) Experimental data suggesting that inflammation mediated rat liver mitochondrial dysfunction results from secondary hypoxia rather than from direct effects of inflammatory mediators. Front Physiol 4:138. | OXPHOS | N S ROX | Isolated mitochondria | Rat | |
Villarroel 2013 J Trauma Acute Care Surg | 2013 | Villarroel JP, Guan Y, Werlin E, Selak MA, Becker LB, Sims CA (2013) Hemorrhagic shock and resuscitation are associated with peripheral blood mononuclear cell mitochondrial dysfunction and immunosuppression. J Trauma Acute Care Surg 75:24-31. | LEAK ROUTINE ET | S ROX | Intact cells | Rat | Blood cells Lymphocyte |
Alandijany 2013 J Neurovirol | 2013 | Alandijany T, Kammouni W, Roy Chowdhury SK, Fernyhough P, Jackson AC (2013) Mitochondrial dysfunction in rabies virus infection of neurons. J Neurovirol 19:537-49. | LEAK OXPHOS ET | N CIV ROX | Permeabilized cells | Rat | Nervous system |
Gispert 2013 Hum Mol Genet | 2013 | Gispert S, Parganlija D, Klinkenberg M, Dröse S, Wittig I, Mittelbronn M, Grzmil P, Koob S, Hamann A, Walter M, Büchel F, Adler T, Hrabé de Angelis M, Busch DH, Zell A, Reichert AS, Brandt U, Osiewacz HD, Jendrach M, Auburger G (2013) Loss of mitochondrial peptidase Clpp leads to infertility, hearing loss plus growth retardation via accumulation of CLPX, mtDNA and inflammatory factors. Hum Mol Genet 22:4871-87. | LEAK OXPHOS | N S ROX | Isolated mitochondria | Mouse | Heart Nervous system Liver Genital |
Hroudova 2013 Mitochondrion | 2013 | Hroudová J, Fišar Z, Kitzlerová E, Zvěřová M, Raboch J (2013) Mitochondrial respiration in blood platelets of depressive patients. Mitochondrion 13:795-800. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | Blood cells Platelet |
Chacko 2013 Lab Invest | 2013 | Chacko BK, Kramer PA, Ravi S, Johnson MS, Hardy RW, Ballinger SW, Darley-Usmar VM (2013) Methods for defining distinct bioenergetic profiles in platelets, lymphocytes, monocytes, and neutrophils, and the oxidative burst from human blood. Lab Invest 93:690-700. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells Other cell lines Lymphocyte Platelet |
Jacobs 2013 Am J Physiol Endocrinol Metab | 2013 | Jacobs R, Meinild AK, Nordsborg NB, Lundby C (2013) Lactate oxidation in human skeletal muscle mitochondria. Am J Physiol Endocrinol Metab 304:686-94. | LEAK OXPHOS | F N S NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Wuest 2012 Am J Physiol Heart Circ Physiol | 2012 | Wuest RC, Myers DS, Stones R, Benoist D, Robinson PA, Boyle JP, Peers C, White E, Rossiter HB (2012) Regional skeletal muscle remodeling and mitochondrial dysfunction in right ventricular heart failure. Am J Physiol Heart Circ Physiol 302: H402-H411. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Rat | Skeletal muscle |
Strobel 2012 Front Zool | 2012 | Strobel A, Bennecke S, Leo E, Mintenbeck K, Pörtner HO, Mark FC (2012) Metabolic shifts in the Antarctic fish Notothenia rossii in response to rising temperature and PCO2. Front Zool 9:28. | LEAK OXPHOS | N S NS ROX | Isolated mitochondria | Fishes | Liver |
Friederich-Persson 2012 Diabetologia | 2012 | Friederich-Persson M, Franzén S, Catrina SB, Dallner G, Hansell P, Brismar K, Palm F (2012) Coenzyme Q10 prevents GDP-sensitive mitochondrial uncoupling, glomerular hyperfiltration and proteinuria in kidneys from db/db mice as a model of type 2 diabetes. Diabetologia 55:1535-43. | LEAK OXPHOS | N ROX | Isolated mitochondria | Mouse | Kidney |
Pesta 2012 Methods Mol Biol | 2012 | Pesta D, Gnaiger E (2012) High-resolution respirometry. OXPHOS protocols for human cells and permeabilized fibers from small biopsies of human muscle. Methods Mol Biol 810:25-58. https://doi.org/10.1007/978-1-61779-382-0_3 | LEAK ROUTINE OXPHOS ET | F N S NS ROX | Permeabilized cells Permeabilized tissue Intact cells | Human | Skeletal muscle Other cell lines HEK Fibroblast HUVEC |
Stephenson 2012 J Appl Physiol (1985) | 2012 | Stephenson EJ, Stepto NK, Koch LG, Britton SL, Hawley JA (2012) Divergent skeletal muscle respiratory capacities in rats artificially selected for high and low running ability: a role for Nor1? J Appl Physiol (1985) 113:1403-12. | LEAK OXPHOS ET | F N S CIV NS Other combinations ROX | Permeabilized tissue | Rat | Skeletal muscle |
Correa 2012 Mitochondrion | 2012 | Correa CC, Aw WC, Melvin RG, Pichaud N, Ballard JWO (2012) Mitochondrial DNA variants influence mitochondrial bioenergetics in Drosophila melanogaster. Mitochondrion 12:459-64. | LEAK OXPHOS ET | N S ROX | Permeabilized tissue Isolated mitochondria | Drosophila Hexapods | Skeletal muscle |
Colleoni 2012 Placenta | 2012 | Colleoni F, Morash AJ, Ashmore T, Monk M, Burton GJ, Murray AJ (2012) Cryopreservation of placental biopsies for mitochondrial respiratory analysis. Placenta 33:122-3. | LEAK OXPHOS | N ROX | Permeabilized tissue | Human | Genital |
Welchen 2012 Biochim Biophys Acta | 2012 | Welchen E, Hildebrandt TM, Lewejohann D, Gonzalez DH, Braun HP (2012) Lack of cytochrome c in Arabidopsis decreases stability of Complex IV and modifies redox metabolism without affecting Complexes I and III. Biochim Biophys Acta 1817:990-1001. | ROUTINE OXPHOS | S ROX | Isolated mitochondria Intact cells | Plants | |
Goo 2012 PLoS One | 2012 | Goo CK, Lim HY, Ho QS, Too HP, Clement MV, Wong KP (2012) PTEN/Akt signaling controls mitochondrial respiratory capacity through 4E-BP1. PLoS One 7:e45806. | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Fibroblast |
Hughey 2012 Cell Regen (Lond) | 2012 | Hughey CC, Alfaro MP, Belke DD, Rottman JN, Young PP, Wasserman DH, Shearer J (2012) Increased oxygen consumption and OXPHOS potential in superhealer mesenchymal stem cells. Cell Regen (Lond) 1:3. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Intact cells Permeabilized cells | Mouse Rat | Heart Stem cells |
Lanza 2012 Cell Metab | 2012 | Lanza IR, Zabielski P, Klaus KA, Morse DM, Heppelmann CJ, Bergen HR 3rd, Dasari S, Walrand S, Short KR, Johnson ML, Robinson MM, Schimke JM, Jakaitis DR, Asmann YW, Sun Z, Nair KS (2012) Chronic caloric restriction preserves mitochondrial function in senescence without increasing mitochondrial biogenesis. Cell Metab 16:777-88. | LEAK OXPHOS | N S NS ROX | Permeabilized tissue Isolated mitochondria | Mouse | Skeletal muscle |
Zangl 2011 Thesis Universität Ulm - Germany | 2011 | Zangl Q (2011) Funktion hepatischer Mitochondrien nach Ischämie-Reperfusion und vorheriger Behandlung mit Schwefelwasserstoff im Großtierversuch. Thesis Universität Ulm - Germany 69pp. | LEAK OXPHOS ET | S NS ROX | Permeabilized cells | Pig | Liver |
Timmers 2011 Cell Metab | 2011 | Timmers S, Konings E, Bilet L, Houtkooper RH, van de Weijer T, Goossens GH, Hoeks J, van der Krieken S, Ryu D, Kersten S, Moonen-Kornips E, Hesselink MK, Kunz I, Schrauwen-Hinderling VB, Blaak EE, Auwerx J, Schrauwen P (2011) Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans. Cell Metab 14:612-22. | LEAK OXPHOS ET | F N NS Other combinations ROX | Permeabilized tissue | Human | Skeletal muscle |
Pecinova 2011 Mitochondrion | 2011 | Pecinova A, Drahota Z, Nuskova H, Pecina P, Houstek J (2011) Evaluation of basic mitochondrial functions using rat tissue homogenates. Mitochondrion 11:722-8. | LEAK OXPHOS ET | N ROX | Homogenate Isolated mitochondria | Rat | Heart Nervous system Liver Kidney |
Lemieux 2011 Int J Biochem Cell Biol | 2011 | Lemieux H, Semsroth S, Antretter H, Höfer D, Gnaiger E (2011) Mitochondrial respiratory control and early defects of oxidative phosphorylation in the failing human heart. Int J Biochem Cell Biol 43:1729–38. https://doi.org/10.1016/j.biocel.2011.08.008 | LEAK OXPHOS ET | F N S CIV NS ROX | Permeabilized tissue | Human | Heart |
Djafarzadeh 2011 Mitochondrion | 2011 | Djafarzadeh S, Vuda M, Takala J, Ochs M, Jakob SM (2011) Toll-like receptor-3-induced mitochondrial dysfunction in cultured human hepatocytes. Mitochondrion 11:83-8. | LEAK OXPHOS | N S CIV ROX | Permeabilized cells | Human | Liver |
Guillet 2011 FASEB J | 2011 | Guillet V, Gueguen N, Cartoni R, Chevrollier A, Desquiret V, Angebault C, Amati-Bonneau P, Procaccio V, Bonneau D, Martinou JC, Reynier P (2011) Bioenergetic defect associated with mKATP channel opening in a mouse model carrying a mitofusin 2 mutation. FASEB J 25:1618-27. | LEAK OXPHOS ET | N S Gp CIV ROX | Isolated mitochondria | Mouse | Nervous system |
Esteves 2010 J Neurochem | 2010 | Esteves AR, Lu J, Rodova M, Onyango I, Lezi E, Dubinsky R, Lyons KE, Pahwa R, Burns JM, Cardoso SM, Swerdlow RH (2010) Mitochondrial respiration and respiration-associated proteins in cell lines created through Parkinson's subject mitochondrial transfer. J Neurochem 113:674-82. | LEAK ROUTINE ET | N ROX | Intact cells | Human | Blood cells Platelet |
Hilton 2010 J Comp Physiol B | 2010 | Hilton Z, Clements KD, Hickey AJ (2010) Temperature sensitivity of cardiac mitochondria in intertidal and subtidal triplefin fishes. J Comp Physiol B 180:979-90. | OXPHOS LEAK ET | CIV NS ROX | Permeabilized tissue | Fishes | Heart |
Sjoevall 2010 Crit Care | 2010 | Sjoevall F, Morota S, Hansson Magnus J, Friberg H, Gnaiger E, Elmer E (2010) Temporal increase of platelet mitochondrial respiration is negatively associated with clinical outcome in patients with sepsis. Crit Care 14:R214. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | Blood cells Platelet |
Aguirre 2010 Biochim Biophys Acta | 2010 | Aguirre E, Rodríguez-Juárez F, Bellelli A, Gnaiger E, Cadenas S (2010) Kinetic model of the inhibition of respiration by endogenous nitric oxide in intact cells. Biochim Biophys Acta 1797:557-65. https://doi.org/10.1016/j.bbabio.2010.01.033 | LEAK ROUTINE ET | ROX | Intact cells Enzyme Oxidase;biochemical oxidation | HEK | |
Fornuskova 2010 Thesis | 2010 | Fornůsková D (2010) Biochemical and molecular studies of cytochrome c oxidase and ATP synthase deficiencies. PhD Thesis p93. | LEAK OXPHOS | N S CIV NS ROX | Permeabilized cells Permeabilized tissue | Human | Heart Skeletal muscle Nervous system Liver HEK Fibroblast |
Lagoutte 2010 Biochim Biophys Acta | 2010 | Lagoutte E, Mimoun S, Andriamihaja M, Chaumontet C, Blachier F, Bouillaud F (2010) Oxidation of hydrogen sulfide remains a priority in mammalian cells and causes reverse electron transfer in colonocytes. Biochim Biophys Acta 1797:1500-11. | LEAK ROUTINE | Other combinations ROX | Isolated mitochondria Intact cells | Mouse | Heart Nervous system Liver Kidney CHO |
Sangle 2010 Free Radic Biol Med | 2010 | Sangle GV, Chowdhury SK, Xie X, Stelmack GL, Halayko AJ, Shen GX (2010) Impairment of mitochondrial respiratory chain activity in aortic endothelial cells induced by glycated low-density lipoprotein. Free Radic Biol Med 48:781-90. | OXPHOS | N S CIV NS ROX | Permeabilized cells | Pig | Endothelial;epithelial;mesothelial cell |
Eberhart 2009 Leukemia | 2009 | Eberhart K, Renner K, Ritter I, Kastenberger M, Singer K, Hellerbrand C, Kreutz M, Kofler R, Oefner PJ (2009) Low doses of 2-deoxy-glucose sensitize acute lymphoblastic leukemia cells to glucocorticoid-induced apoptosis. Leukemia 23:2167-70. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells Lymphocyte |
Keeney 2009 Hum Gene Ther | 2009 | Keeney PM, Quigley CK, Dunham LD, Papageorge CM, Iyer S, Thomas RR, Schwarz KM, Trimmer PA, Khan SM, Portell FR, Bergquist KE, Bennett JP (2009) Mitochondrial gene therapy augments mitochondrial physiology in a Parkinson's disease cell model. Hum Gene Ther 20:897-907. | OXPHOS LEAK ROUTINE ET | ROX | Intact cells | Human | Nervous system Neuroblastoma |
Rhein 2009 Cell Mol Neurobiol | 2009 | Rhein V, Baysang G, Rao S, Meier F, Bonert A, Müller-Spahn F, Eckert A (2009) Amyloid-beta leads to impaired cellular respiration, energy production and mitochondrial electron chain complex activities in human neuroblastoma cells. Cell Mol Neurobiol 29:1063-71. | LEAK | N S NS ROX | Permeabilized cells | Human | Nervous system Neuroblastoma |
Rhein 2009 Proc Natl Acad Sci U S A | 2009 | Rhein V, Song X, Wiesner A, Ittner LM, Baysang G, Meier F, Ozmen L, Bluethmann H, Dröse S, Brandt U, Savaskan E, Czech C, Götz J, Eckert A (2009) Amyloid-beta and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice. Proc Natl Acad Sci U S A 106:20057-62. | LEAK OXPHOS ET | N CIV ROX | Isolated mitochondria | Mouse | Nervous system |
Tahara 2009 Free Radic Biol Med | 2009 | Tahara EB, Navarete FD, Kowaltowski AJ (2009) Tissue-, substrate-, and site-specific characteristics of mitochondrial reactive oxygen species generation. Free Radic Biol Med 46:1283-97. | LEAK ET OXPHOS | F N NS ROX S Gp | Isolated mitochondria | Rat | Heart Skeletal muscle Nervous system Liver Kidney |
Pereira 2009 Biochem J | 2009 | Pereira da Silva AP, El-Bacha T, Kyaw N, dos Santos RS, Da Silva WS, Almeida FC, Da Poian AT, Galina A (2009) Inhibition of energy-producing pathways of HepG2 cells by 3-bromopyruvate. Biochem J 417:717-26. | LEAK ROUTINE OXPHOS ET | S ROX | Permeabilized cells Intact cells | Human | Liver |
Regueira 2009 Liver Int | 2009 | Regueira T, Lepper PM, Brandt S, Ochs M, Vuda M, Takala J, Jakob SM, Djafarzadeh S (2009) Hypoxia inducible factor-1alpha induction by tumour necrosis factor-alpha, but not by toll-like receptor agonists, modulates cellular respiration in cultured human hepatocytes. Liver Int 10:1582-92. | LEAK OXPHOS | N S CIV ROX | Permeabilized cells | Human | Liver |
Gnaiger 2008 POS | 2008 | Gnaiger E (2008) Polarographic oxygen sensors, the oxygraph and high-resolution respirometry to assess mitochondrial function. In: Mitochondrial dysfunction in drug-induced toxicity (Dykens JA, Will Y, eds) John Wiley & Sons, Inc, Hoboken, NJ:327-52. | LEAK ROUTINE ET | ROX | Permeabilized cells Permeabilized tissue Intact cells | Mouse | Blood cells |
Rostrup M 2008 Amino Acids | 2008 | Rostrup M, Fossbakk A, Hauge A, Kleppe R, Gnaiger E, Haavik J (2008) Oxygen dependence of tyrosine hydroxylase. Amino Acids 34:455-64. | ROX | Enzyme Oxidase;biochemical oxidation | Human | ||
Hoeks 2008 FEBS Lett | 2008 | Hoeks J, Briedé JJ, de Vogel J, Schaart G, Nabben M, Moonen-Kornips E, Hesselink MK, Schrauwen P (2008) Mitochondrial function, content and ROS production in rat skeletal muscle: Effect of high-fat feeding. FEBS Lett 582:510-16. | ROUTINE OXPHOS ET | F NS ROX | Isolated mitochondria | Rat | Skeletal muscle |
Spacek 2008 Int J Biochem Cell Biol | 2008 | Spacek T, Santorová J, Zacharovová K, Berková Z, Hlavatá L, Saudek F, Jezek P (2008) Glucose-stimulated insulin secretion of insulinoma INS-1E cells is associated with elevation of both respiration and mitochondrial membrane potential. Int J Biochem Cell Biol 40:1522-35. | LEAK ROUTINE ET | ROX | Intact cells | Rat | Islet cell;pancreas;thymus Other cell lines |
Giulivi 2008 Biochem J | 2008 | Giulivi C, Ross-Inta C, Horton AA, Luckhart S (2008) Metabolic pathways in Anopheles stephensi mitochondria. Biochem J 415:309-16. | LEAK OXPHOS | F N S Gp CIV Other combinations ROX | Isolated mitochondria | Human Rat Birds Hexapods | Skeletal muscle |
El-Bacha 2007 Biochim Biophys Acta | 2007 | El-Bacha T, Midlej V, Pereira da Silva AP, Silva da Costa L, Benchimol M, Galina A, Da Poian AT (2007) Mitochondrial and bioenergetic dysfunction in human hepatic cells infected with dengue 2 virus. Biochim Biophys Acta 1772:1158-66. | LEAK ROUTINE OXPHOS ET | N S ROX | Permeabilized cells Intact cells | Human | Liver |
Wu 2007 Am J Physiol Cell Physiol | 2007 | Wu M, Neilson A, Swift AL, Moran R, Tamagnine J, Parslow D, Armistead S, Lemire K, Orrell J, Teich J, Chomicz S, Ferrick DA (2007) Multiparameter metabolic analysis reveals a close link between attenuated mitochondrial bioenergetic function and enhanced glycolysis dependency in human tumor cells. https://doi.org/10.1152/ajpcell.00247.2006 | LEAK ROUTINE ET | ROX | Intact cells | Human | |
Deschauer 2006 Mol Genet Metab | 2006 | Deschauer M, Gizatullina Z, Schulze A, Pritsch M, Knöppel C, Knape M, Zierz S, Gellerich FN (2006) Molecular and biochemical investigations in fumarase deficiency. Mol Genet Metab 88:146-52. | LEAK OXPHOS ET | N S ROX | Permeabilized cells Intact cells | Human | Fibroblast |
Jarmuszkiewicz 2005 Biochim Biophys Acta | 2005 | Jarmuszkiewicz W, Czarna M, Sluse FE (2005) Substrate kinetics of the Acanthamoeba castellanii alternative oxidase and the effects of GMP. Biochim Biophys Acta 1708:71-8. | OXPHOS | ROX | Oxidase;biochemical oxidation | Protists | |
Kuznetsov 2004 Am J Physiol Heart Circ Physiol | 2004 | Kuznetsov AV, Schneeberger S, Seiler R, Brandacher G, Mark W, Steurer W, Saks V, Usson Y, Margreiter R, Gnaiger E (2004) Mitochondrial defects and heterogeneous cytochrome c release after cardiac cold ischemia and reperfusion. Am J Physiol Heart Circ Physiol 286:H1633–41. | LEAK OXPHOS | N S CIV ROX | Intact organ Permeabilized tissue SMP Enzyme | Rat | Heart |
Kraft 2004 Thesis Universität Halle-Wittenberg - Germany | 2004 | Kraft A (2004) Langzeitstabilität der Mitochondrienfunktion permeabilisierter Muskelfasern in der Diagnostik mitochondrialer Enzephalomyopathien. Thesis Universität Halle-Wittenberg - Germany 74pp. | LEAK OXPHOS | N S NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Gnaiger 2003 Adv Exp Med Biol | 2003 | Gnaiger E (2003) Oxygen conformance of cellular respiration. A perspective of mitochondrial physiology. https://doi.org/10.1007/978-1-4419-8997-0_4 | ROUTINE OXPHOS | N ROX | Intact cells Permeabilized cells Permeabilized tissue Isolated mitochondria Oxidase;biochemical oxidation | Human Rat | Heart Liver Endothelial;epithelial;mesothelial cell Fibroblast |
Rosenfeld 2003 Yeast | 2003 | Rosenfeld E, Beauvoit B (2003) Role of the non-respiratory pathways in the utilization of molecular oxygen by Saccharomyces cerevisiae. Yeast 20:1115-44. | ROX | Oxidase;biochemical oxidation Intact cells | Saccharomyces cerevisiae Fungi | ||
Kuznetsov 2002 Anal Biochem | 2002 | Kuznetsov AV, Strobl D, Ruttmann E, Königsrainer A, Margreiter R, Gnaiger E (2002) Evaluation of mitochondrial respiratory function in small biopsies of liver. Anal Biochem 305:186-94. | LEAK OXPHOS | N S CIV ROX | Permeabilized tissue | Pig | Liver |
Huetter 2002 Mol Biol Rep | 2002 | Hütter E, Renner K, Jansen-Dürr P, Gnaiger E (2002) Biphasic oxygen kinetics of cellular respiration and linear oxygen dependence of antimycin A inhibited oxygen consumption. Mol Biol Rep 29:83-7. | ROUTINE | ROX | Intact cells | Human | Fibroblast |
Rosenfeld 2002 Yeast | 2002 | Rosenfeld E, Beauvoit B, Rigoulet M, Salmon JM (2002) Non-respiratory oxygen consumption pathways in anaerobically-grown Saccharomyces cerevisiae: evidence and partial characterization. Yeast 19:1299-321. | ROX | Oxidase;biochemical oxidation Intact cells | Saccharomyces cerevisiae Fungi | Blood cells | |
Stadlmann 2002 Transplantation | 2002 | Stadlmann S, Rieger G, Amberger A, Kuznetsov AV, Margreiter R, Gnaiger E (2002) H2O2-mediated oxidative stress versus cold ischemia-reperfusion: mitochondrial respiratory defects in cultured human endothelial cells. Transplantation 74:1800-3. | LEAK ROUTINE OXPHOS | N S CIV ROX | Permeabilized cells Intact cells | Human | Endothelial;epithelial;mesothelial cell |
Villani 1997 Proc Natl Acad Sci U S A | 1997 | Villani G, Attardi G (1997) In vivo control of respiration by cytochrome c oxidase in wild-type and mitochondrial DNA mutation-carrying human cells. Proc Natl Acad Sci U S A 94:1166-71. | ROUTINE ET OXPHOS | N S Gp ROX | Intact cells Permeabilized cells | Human | Fibroblast |
Steinlechner-Maran 1997 Transplantation | 1997 | Steinlechner-Maran R, Eberl T, Kunc M, Schröcksnadel H, Margreiter R, Gnaiger E (1997) Respiratory defect as an early event in preservation/reoxygenation injury in endothelial cells. Transplantation 63:136-42. | ROUTINE ET | ROX | Intact cells | Human | Endothelial;epithelial;mesothelial cell HUVEC |
Vamecq 1987 Biochem J | 1987 | Vamecq J, Schepers L, Parmentier G, Mannaerts GP (1987) Inhibition of peroxisomal fatty acyl-CoA oxidase by antimycin A. Biochem J 248:603-7. | F ROX | Oxidase;biochemical oxidation | |||
Keilin 1929 Proc R Soc London Ser B | 1929 | Keilin D (1929) Cytochrome and respiratory enzymes. Proc R Soc London Ser B 104:206-52. | ROX |